1  675 126 EFFECT OF A SIX-MONTH YOGA EXERCISE INTERVENTION ON FITNESS OUTCOMES FOR BREAST CANCER SURVIVORS. YOGA-BASED EXERCISE HAS PROVEN TO BE BENEFICIAL FOR PRACTITIONERS, INCLUDING CANCER SURVIVORS. THIS STUDY REPORTS ON THE IMPROVEMENTS IN PHYSICAL FITNESS FOR 20 BREAST CANCER SURVIVORS WHO PARTICIPATED IN A SIX-MONTH YOGA-BASED EXERCISE PROGRAM (YE). RESULTS ARE COMPARED TO A COMPREHENSIVE EXERCISE (CE) PROGRAM GROUP AND A COMPARISON (C) EXERCISE GROUP WHO CHOSE THEIR OWN EXERCISES. "PRE" AND "POST" FITNESS ASSESSMENTS INCLUDED MEASURES OF ANTHROPOMETRICS, CARDIORESPIRATORY CAPACITY, STRENGTH AND FLEXIBILITY. DESCRIPTIVE STATISTICS, EFFECT SIZE (D), DEPENDENT SAMPLE 'T' TESTS FOR ALL OUTCOME MEASURES WERE CALCULATED FOR THE YE GROUP. SIGNIFICANT IMPROVEMENTS INCLUDED: DECREASED % BODY FAT (-3.00%, D = -0.44, P < 0.001); INCREASED SIT TO STAND LEG STRENGTH REPETITIONS (2.05, D = 0.48, P = 0.003); FORWARD REACH (3.59 CM, D = 0.61, P = 0.01); AND RIGHT ARM SAGITTAL RANGE OF MOTION (6.50 DEGREES , D = 0.92, P = 0.05). TO COMPARE YE OUTCOMES WITH THE OTHER TWO GROUPS, A ONE-WAY ANALYSIS OF VARIANCE (ANOVA) WAS USED. YE PARTICIPANTS SIGNIFICANTLY OUTPERFORMED C PARTICIPANTS ON "FORWARD REACH" (3.59 CM GAINED VERSUS -2.44 CM LOST), (P = 0.009) AND OUTPERFORMED CE PARTICIPANTS (3.59 CM GAINED VERSUS 1.35 CM GAINED), BUT NOT STATISTICALLY SIGNIFICANT. OUR RESULTS SUPPORT YOGA-BASED EXERCISE MODIFIED FOR BREAST CANCER SURVIVORS AS SAFE AND EFFECTIVE.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
2 1018  87 EFFECTS OF SIX MONTHS OF YOGA ON INFLAMMATORY SERUM MARKERS PROGNOSTIC OF RECURRENCE RISK IN BREAST CANCER SURVIVORS. YOGA-BASED EXERCISE HAS PROVEN TO BE BENEFICIAL FOR PRACTITIONERS, INCLUDING CANCER SURVIVORS. THIS STUDY REPORTS ON THE EFFECT ON INFLAMMATORY BIOLOGICAL MARKERS FOR 20 BREAST CANCER SURVIVORS WHO PARTICIPATED IN A SIX-MONTH YOGA-BASED (YE) EXERCISE PROGRAM. RESULTS ARE COMPARED TO A COMPREHENSIVE EXERCISE (CE) PROGRAM GROUP AND A COMPARISON (C) EXERCISE GROUP WHO CHOSE THEIR OWN EXERCISES. "PRE" AND "POST" ASSESSMENTS INCLUDED MEASURES OF ANTHROPOMETRICS, CARDIORESPIRATORY CAPACITY, AND INFLAMMATORY MARKERS INTERLEUKIN 6 (IL-6), INTERLEUKIN 8 (IL-8), TUMOR NECROSIS FACTOR ALPHA (TNFALPHA) AND C-REACTIVE PROTEIN (CRP). DESCRIPTIVE STATISTICS, EFFECT SIZE (D), AND DEPENDENT SAMPLE 'T' TESTS FOR ALL OUTCOME MEASURES WERE CALCULATED FOR THE YE GROUP. SIGNIFICANT IMPROVEMENTS WERE SEEN IN DECREASED % BODY FAT, (-3.00%, D = -0.44, P = <.001) BUT NOT IN CARDIORESPIRATORY CAPACITY OR IN INFLAMMATORY SERUM MARKERS. TO COMPARE YE OUTCOMES WITH THE OTHER TWO GROUPS, A ONE-WAY ANALYSIS OF CO-VARIANCE (ANCOVA) WAS USED, CONTROLLING FOR AGE, BMI, CARDIORESPIRATORY CAPACITY AND SERUM MARKER BASELINE VALUES. WE FOUND NO DIFFERENCES BETWEEN GROUPS. MOREOVER, WE DID NOT SEE SIGNIFICANT CHANGES IN ANY INFLAMMATORY MARKER FOR ANY GROUP. OUR RESULTS SUPPORT THE EFFECTIVENESS OF YOGA-BASED EXERCISE MODIFIED FOR BREAST CANCER SURVIVORS FOR IMPROVING BODY COMPOSITION. LARGER STUDIES ARE NEEDED TO DETERMINE IF THERE ARE SIGNIFICANT CHANGES IN INFLAMMATORY SERUM MARKERS AS A RESULT OF SPECIFIC EXERCISE MODALITIES.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
3 1113  40 EFFICACY OF A BIOMECHANICALLY-BASED YOGA EXERCISE PROGRAM IN KNEE OSTEOARTHRITIS: A RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: CERTAIN EXERCISES COULD OVERLOAD THE OSTEOARTHRITIC KNEE. WE DEVELOPED AN EXERCISE PROGRAM FROM YOGA POSTURES WITH A MINIMAL KNEE ADDUCTION MOMENT FOR KNEE OSTEOARTHRITIS. THE PURPOSE WAS TO COMPARE THE EFFECTIVENESS OF THIS BIOMECHANICALLY-BASED YOGA EXERCISE (YE), WITH TRADITIONAL EXERCISE (TE), AND A NO-EXERCISE ATTENTION-EQUIVALENT CONTROL (NE) FOR IMPROVING PAIN, SELF-REPORTED PHYSICAL FUNCTION AND MOBILITY PERFORMANCE IN WOMEN WITH KNEE OSTEOARTHRITIS. DESIGN: SINGLE-BLIND, THREE-ARM RANDOMIZED CONTROLLED TRIAL. SETTING: COMMUNITY IN SOUTHWESTERN ONTARIO, CANADA. PARTICIPANTS: A CONVENIENCE SAMPLE OF 31 WOMEN WITH SYMPTOMATIC KNEE OSTEOARTHRITIS WAS RECRUITED THROUGH RHEUMATOLOGY, ORTHOPAEDIC AND PHYSIOTHERAPY CLINICS, NEWSPAPERS AND WORD-OF-MOUTH. INTERVENTIONS: PARTICIPANTS WERE STRATIFIED BY DISEASE SEVERITY AND RANDOMLY ALLOCATED TO ONE OF THREE 12-WEEK, SUPERVISED INTERVENTIONS. YE INCLUDED BIOMECHANICALLY-BASED YOGA EXERCISES; TE INCLUDED TRADITIONAL LEG STRENGTHENING ON MACHINES; AND NE INCLUDED MEDITATION WITH NO EXERCISE. PARTICIPANTS WERE ASKED TO ATTEND THREE 1-HOUR GROUP CLASSES/SESSIONS EACH WEEK. MEASUREMENTS: PRIMARY OUTCOMES WERE PAIN, SELF-REPORTED PHYSICAL FUNCTION AND MOBILITY PERFORMANCE. SECONDARY OUTCOMES WERE KNEE STRENGTH, DEPRESSION, AND HEALTH-RELATED QUALITY OF LIFE. ALL WERE ASSESSED BY A BLINDED ASSESSOR AT BASELINE AND IMMEDIATELY FOLLOWING THE INTERVENTION. RESULTS: THE YE GROUP DEMONSTRATED GREATER IMPROVEMENTS IN KOOS PAIN (MEAN DIFFERENCE OF 22.9 [95% CI, 6.9 TO 38.8; P = 0.003]), INTERMITTENT PAIN (MEAN DIFFERENCE OF -19.6 [95% CI, -34.8 TO -4.4; P = 0.009]) AND SELF-REPORTED PHYSICAL FUNCTION (MEAN DIFFERENCE OF 17.2 [95% CI, 5.2 TO 29.2; P = 0.003]) COMPARED TO NE. IMPROVEMENTS IN THESE OUTCOMES WERE SIMILAR BETWEEN YE AND TE. HOWEVER, TE DEMONSTRATED A GREATER IMPROVEMENT IN KNEE FLEXOR STRENGTH COMPARED TO YE (MEAN DIFFERENCE OF 0.1 [95% CI, 0.1 TO 0.2]. IMPROVEMENTS FROM BASELINE TO FOLLOW-UP WERE PRESENT IN QUALITY OF LIFE SCORE FOR YE AND KNEE FLEXOR STRENGTH FOR TE, WHILE BOTH ALSO DEMONSTRATED IMPROVEMENTS IN MOBILITY. NO IMPROVEMENT IN ANY OUTCOME WAS PRESENT IN NE. CONCLUSIONS: THE BIOMECHANICALLY-BASED YOGA EXERCISE PROGRAM PRODUCED CLINICALLY MEANINGFUL IMPROVEMENTS IN PAIN, SELF-REPORTED PHYSICAL FUNCTION AND MOBILITY IN WOMEN WITH CLINICAL KNEE OA COMPARED TO NO EXERCISE. WHILE NOT STATISTICALLY SIGNIFICANT, IMPROVEMENTS IN THESE OUTCOMES WERE LARGER THAN THOSE ELICITED FROM THE TRADITIONAL EXERCISE-BASED PROGRAM. THOUGH THIS MAY SUGGEST THAT THE YOGA PROGRAM MAY BE MORE EFFICACIOUS FOR KNEE OA, FUTURE RESEARCH STUDYING A LARGER SAMPLE IS REQUIRED. TRIAL REGISTRATION: CLINICALTRIALS.GOV (NCT02370667).	2018	

4  969  38 EFFECTS OF AN 8-MONTH YOGA INTERVENTION ON ARTERIAL COMPLIANCE AND MUSCLE STRENGTH IN PREMENOPAUSAL WOMEN. PREVIOUS STUDIES HAVE INDICATED THAT YOGA EXERCISE HAS A POSITIVE EFFECT ON REDUCING BLOOD PRESSURE AND HEART RATE. HOWEVER, NO RANDOMIZED CONTROLLED STUDIES TO DATE HAVE INVESTIGATED ITS EFFECTS ON ARTERIAL COMPLIANCE. THE PURPOSE OF THIS STUDY WAS TO INVESTIGATE THE EFFECTS OF AN 8-MONTH YOGA INTERVENTION ON ARTERIAL COMPLIANCE AND MUSCLE STRENGTH IN NORMAL PREMENOPAUSAL WOMEN 35-50 YEARS OF AGE. THIRTY-FOUR WOMEN WERE RANDOMLY ASSIGNED EITHER TO A YOGA EXERCISE GROUP (YE, N = 16) OR A CONTROL GROUP (CON, N = 18). PARTICIPANTS IN YE GROUP PERFORMED 60 MINUTES OF AN ASHTANGA YOGA SERIES 2 TIMES/WEEK WITH ONE DAY BETWEEN SESSIONS FOR 8 MONTHS. EACH YOGA SESSION CONSISTED OF 15 MINUTES OF WARM-UP EXERCISES, 35 MINUTES OF ASHTANGA YOGA POSTURES AND 10 MINUTES OF COOL-DOWN WITH RELAXATION; AND THE SESSION INTENSITY WAS PROGRESSIVELY INCREASED DURING THE 8 MONTHS. PARTICIPANTS IN CON WERE ENCOURAGED TO MAINTAIN THEIR NORMAL DAILY LIFESTYLES MONITORED BY THE BONE-SPECIFIC PHYSICAL ACTIVITY QUESTIONNAIRE AT 2 MONTH INTERVALS FOR 8 MONTHS. ARTERIAL COMPLIANCE (PULSE CONTOUR ANALYSIS) AND MUSCLE STRENGTH (1 REPETITION MAXIMUM) WERE ASSESSED AT BASELINE AND AFTER THE INTERVENTION. ARTERIAL COMPLIANCE OF THE LARGE AND SMALL ARTERIES WAS NOT AFFECTED BY THE 8 MONTH YOGA TRAINING (P > 0.05). ALSO, THERE WERE NO SIGNIFICANT (P > 0.05) GROUP, TIME, OR GROUP X TIME INTERACTION EFFECTS FOR CARDIOVASCULAR VARIABLES. YE GROUP SIGNIFICANTLY (P < 0.01) IMPROVED LEG PRESS MUSCLE STRENGTH COMPARED TO CON (11.4% VS. -6.5%). EIGHT MONTHS OF ASHTANGA YOGA TRAINING WAS BENEFICIAL FOR IMPROVING LEG PRESS STRENGTH, BUT NOT ARTERIAL COMPLIANCE IN PREMENOPAUSAL WOMEN. KEY POINTSTHE 8 MONTH YOGA TRAINING DID NOT AFFECT ARTERIAL COMPLIANCE OF THE LARGE AND SMALL ARTERIES.NONE OF THE CARDIOVASCULAR VARIABLES WERE CHANGED BY THE YOGA INTERVENTION.ISOTONIC MUSCLE STRENGTH WAS NOT ALTERED BY THE YOGA INTERVENTION, WITH THE EXCEPTION OF LEG PRESS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
5  968  37 EFFECTS OF AN 8-MONTH ASHTANGA-BASED YOGA INTERVENTION ON BONE METABOLISM IN MIDDLE-AGED PREMENOPAUSAL WOMEN: A RANDOMIZED CONTROLLED STUDY. ALTHOUGH YOGA HAS THE POTENTIAL TO BE AN ALTERNATIVE PHYSICAL ACTIVITY TO ENHANCE BONE HEALTH, THERE IS A LACK OF HIGH QUALITY EVIDENCE FOR THIS TYPE OF INTERVENTION. THE PURPOSE OF THIS RANDOMIZED CONTROLLED TRIAL WAS TO EXAMINE THE EFFECTS OF A PROGRESSIVE 8-MONTH ASHTANGA-BASED YOGA PROGRAM ON BONE TURNOVER MARKERS (BTM), AREAL BONE MINERAL DENSITY (ABMD) AND VOLUMETRIC BONE CHARACTERISTICS IN PREMENOPAUSAL WOMEN. THIRTY-FOUR PREMENOPAUSAL WOMEN (35-50 YEARS) WERE RANDOMLY ASSIGNED EITHER TO A YOGA GROUP (YE, N = 16) OR A CONTROL GROUP (CON, N = 18). PARTICIPANTS IN YE GROUP PERFORMED 60 MINUTES OF AN ASHTANGA-BASED YOGA SERIES 2 TIMES/WEEK WITH ONE DAY BETWEEN SESSIONS FOR 8 MONTHS, AND THE SESSION INTENSITY WAS PROGRESSIVELY INCREASED BY ADDING THE NUMBER OF SUN SALUTATIONS (SS). PARTICIPANTS IN CON WERE ENCOURAGED TO MAINTAIN THEIR NORMAL DAILY LIFESTYLES MONITORED BY THE BONE SPECIFIC PHYSICAL ACTIVITY QUESTIONNAIRE (BPAQ) AT 2 MONTH INTERVALS FOR 8 MONTHS. BODY COMPOSITION WAS MEASURED BY DUAL ENERGY X-RAY ABSORPTIOMETRY (DXA). BONE FORMATION (BONE ALKALINE PHOSPHATASE, BONE ALP) AND BONE RESORPTION (TARTRATE-RESISTANT ACID PHOSPHATASE-5B, TRAP5B) MARKERS WERE ASSESSED AT BASELINE AND AFTER 8 MONTHS. ABMD OF TOTAL BODY, LUMBAR SPINE AND DUAL PROXIMAL FEMUR AND TIBIA BONE CHARACTERISTICS WERE MEASURED USING DXA AND PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY (PQCT), RESPECTIVELY. WE FOUND THAT THE SERUM BONE ALP CONCENTRATIONS WERE MAINTAINED IN YE, BUT SIGNIFICANTLY (P = 0.005) DECREASED IN CON AFTER THE 8 MONTH INTERVENTION, AND THERE WERE SIGNIFICANT (P = 0.002) GROUP DIFFERENCES IN BONE ALP PERCENT CHANGES (YE 9.1 +/- 4.0% VS. CON -7.1 +/- 2.3%). NO CHANGES IN TRAP5B WERE FOUND IN EITHER GROUP. THE 8-MONTH YOGA PROGRAM DID NOT INCREASE ABMD OR TIBIA BONE STRENGTH VARIABLES. BODY COMPOSITION RESULTS SHOWED NO CHANGES IN WEIGHT, FAT MASS, OR % FAT, BUT SMALL SIGNIFICANT INCREASES IN BONE FREE LEAN BODY MASS OCCURRED IN BOTH GROUPS. THE FINDINGS OF THIS STUDY SUGGEST THAT REGULAR LONG-TERM ASHTANGA YOGA HAD A SMALL POSITIVE EFFECT ON BONE FORMATION BUT DID NOT ALTER ABMD OR TIBIA BONE CHARACTERISTICS IN PREMENOPAUSAL WOMEN. KEY POINTSREGULAR LONG-TERM ASHTANGA-BASED YOGA PROGRAM HAD A SMALL POSITIVE EFFECT ON BONE FORMATION, BUT NO EFFECTS WERE FOUND ON BONE RESORPTION.NONE OF THE BONE DENSITY OR GEOMETRY VARIABLES WERE CHANGED BY THE 8-MONTH ASHTANGA-BASED YOGA INTERVENTION.FUTURE YOGA INTERVENTIONS SHOULD FOCUS ON LONGER DURATION AND GREATER FREQUENCY TO ELICIT IMPROVEMENTS IN BONE MINERAL DENSITY.	2015	
                                                                                                                                      
6  170  30 A RANDOMIZED CONTROLLED PILOT STUDY OF THE EFFECTS OF 6-WEEK HIGH INTENSITY HATHA YOGA PROTOCOL ON HEALTH-RELATED OUTCOMES AMONG STUDENTS. OBJECTIVE: MODERN HATHA YOGA EXERCISES (YE) PROVIDE AN ALTERNATIVE FORM OF PHYSICAL ACTIVITY WHICH MAY REDUCE STRESS, FACILITATE RECOVERY AND IMPROVE HEALTH. THIS STUDY INVESTIGATED THE SHORT-TERM EFFECTS OF HIGH INTENSITY HATHA YOGA EXERCISES (HIY) ON HEALTH-RELATED OUTCOMES. METHODS: A 6-WEEK RANDOMIZED CONTROLLED STUDY WAS PERFORMED TO COMPARE HIY WITH A CONTROL GROUP NOT CHANGING THEIR EXERCISE BEHAVIOR. HEALTHY STUDENTS (N=44; MEDIAN AGE: 25 YEARS, RANGE 20-39 YEARS; HIY: N=21, INCLUDING 3 MEN; CONTROL GROUP: N=23, INCLUDING 3 MEN) NOVICE TO YOGA PARTICIPATED IN THE INTERVENTION WHICH INCLUDED ONE WEEKLY CLASS AND RECOMMENDED HOME TRAINING. PARTICIPANTS PROVIDED SELF-REPORTS IN QUESTIONNAIRES BEFORE AND AFTER THE INTERVENTION. SELF-REPORTS INCLUDED ANXIETY AND DEPRESSION (HOSPITAL ANXIETY AND DEPRESSION SCALE), STRESS (PERCEIVED STRESS SCALE), SLEEP QUALITY (PITTSBURGH SLEEP QUALITY INDEX), INSOMNIA (INSOMNIA SEVERITY INDEX), SUBJECTIVE HEALTH COMPLAINTS (COMMON SYMPTOMS IN GENERAL PRACTICE INDEX) AND SELF-RATED HEALTH (SINGLE-ITEM). RESULTS: AFTER THE 6-WEEK INTERVENTION, THERE WERE NO BETWEEN-GROUP DIFFERENCES IN ANXIETY, DEPRESSION, STRESS, SLEEP OR SELF-RATED HEALTH. HOWEVER, WHEN INVESTIGATING ASSOCIATIONS WITHIN THE HIY-GROUP, A HIGHER HIY-DOSE WAS RELATED TO LESS DEPRESSION (R=0.47; P=0.03), IMPROVED SLEEP QUALITY (R=0.55; P=0.01), AND LESS INSOMNIA (R=0.49; P=0.02). CONCLUSIONS: THERE WERE NO SHORT-TERM BETWEEN-GROUP EFFECTS OF HIY ON MENTAL DISTRESS, SLEEP OR SELF-RATED HEALTH. HOWEVER, WITHIN THE HIY-GROUP, A HIGHER DOSE WAS ASSOCIATED WITH IMPROVED MENTAL HEALTH IN TERMS OF DEPRESSION AND WITH IMPROVED SLEEP. ALTHOUGH FUTURE STUDIES WITH LARGER SAMPLES ARE NEEDED, THESE PRELIMINARY FINDINGS SUGGEST SHORT-TERM POSITIVE EFFECTS OF HIY ON HEALTH-RELATED OUTCOMES AMONG STUDENTS. TRIAL REGISTRATION NUMBER: NCT01305096.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
7 2193  31 THE EFFECTS OF YOGA TRAINING AND A SINGLE BOUT OF YOGA ON DELAYED ONSET MUSCLE SORENESS IN THE LOWER EXTREMITY. THE PURPOSE OF THIS STUDY WAS TO DETERMINE THE EFFECTS OF YOGA TRAINING AND A SINGLE BOUT OF YOGA ON THE INTENSITY OF DELAYED ONSET MUSCLE SORENESS (DOMS). 24 YOGA-TRAINED (YT; N = 12) AND NON-YOGA-TRAINED (CON; N = 12), MATCHED WOMEN VOLUNTEERS WERE ADMINISTERED A DOMS-INDUCING BENCH-STEPPING EXERCISE. MUSCLE SORENESS WAS ASSESSED AT BASELINE, 24, 48, 72, 96, AND 120 HOURS AFTER BENCH-STEPPING USING A VISUAL ANALOG SCALE (VAS). GROUPS WERE ALSO COMPARED ON BODY AWARENESS (BA), FLEXIBILITY USING THE SIT-AND-REACH TEST (SR), AND PERCEIVED EXERTION (RPE). STATISTICAL SIGNIFICANCE WAS ACCEPTED AT P </= 0.05. A 2 X 2 MIXED FACTORIAL ANOVA WITH REPEATED MEASURES AT 24 AND 48 HOURS REVEALED A SIGNIFICANT (P < 0.05) GROUP MAIN EFFECT WITH VAS SCORES GREATER FOR CON THAN YT. PAIRED T-TESTS REVEALED THAT IN YT, VAS SCORES WERE HIGHER BEFORE YOGA CLASS THAN AFTER YOGA CLASS AT 24 HOURS (21.4 [+/- 6.9] MM VS. 11.1 [+/- 4.1] MM; P = 0.02). THE SR WAS GREATER IN YT THAN IN CON (65.0 [+/- 7.9] CM VS. 33.3 [+/- 7.0] CM; P < 0.01); HOWEVER, NO DIFFERENCES WERE FOUND BETWEEN YOGA AND CONTROL IN BA (94.0 [+/- 4.4] UNITS VS. 83.8 [+/- 3.7] UNITS; P = 0.21) OR IN RPE AT 5-MINUTE INTERVALS (2.9 [+/- 0.3], 5.3 [+/- 0.8], 5.8 [+/- 0.9], AND 5.2 [+/- 0.8] VS. 2.5 [+/- 0.3], 4.0 [+/- 0.5], 4.2 [+/- 0.3], AND 4.9 [+/- 0.4]. YOGA TRAINING AND A SINGLE BOUT OF YOGA APPEAR TO ATTENUATE PEAK MUSCLE SORENESS IN WOMEN FOLLOWING A BOUT OF ECCENTRIC EXERCISE. THESE FINDINGS HAVE SIGNIFICANT IMPLICATIONS FOR COACHES, ATHLETES, AND THE EXERCISING PUBLIC WHO MAY WANT TO IMPLEMENT YOGA TRAINING AS A PRESEASON REGIMEN OR SUPPLEMENTAL ACTIVITY TO LESSEN THE SYMPTOMS ASSOCIATED WITH MUSCLE SORENESS.	2004	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
8  507  31 COMPARATIVE EFFECTIVENESS OF PILATES AND YOGA GROUP EXERCISE INTERVENTIONS FOR CHRONIC MECHANICAL NECK PAIN: QUASI-RANDOMISED PARALLEL CONTROLLED STUDY. OBJECTIVES: TO DETERMINE THE EFFECTIVENESS OF PILATES AND YOGA GROUP EXERCISE INTERVENTIONS FOR INDIVIDUALS WITH CHRONIC NECK PAIN (CNP). DESIGN: QUASI-RANDOMISED PARALLEL CONTROLLED STUDY. SETTING: COMMUNITY, UNIVERSITY AND PRIVATE PRACTICE SETTINGS IN FOUR LOCATIONS. PARTICIPANTS: FIFTY-SIX INDIVIDUALS WITH CNP SCORING >/=3/10 ON THE NUMERIC PAIN RATING SCALE FOR >3 MONTHS (CONTROLS N=17, PILATES N=20, YOGA N=19). INTERVENTIONS: EXERCISE PARTICIPANTS COMPLETED 12 SMALL-GROUP SESSIONS WITH MODIFICATIONS AND PROGRESSIONS SUPERVISED BY A PHYSIOTHERAPIST. MAIN OUTCOME MEASURES: THE PRIMARY OUTCOME MEASURE WAS THE NECK DISABILITY INDEX (NDI). SECONDARY OUTCOMES WERE PAIN RATINGS, RANGE OF MOVEMENT AND POSTURAL MEASUREMENTS COLLECTED AT BASELINE, 6 WEEKS AND 12 WEEKS. FOLLOW-UP WAS PERFORMED 6 WEEKS AFTER COMPLETION OF THE EXERCISE CLASSES (WEEK 18). RESULTS: NDI DECREASED SIGNIFICANTLY IN THE PILATES {BASELINE: 11.1 [STANDARD DEVIATION (SD) 4.3] VS WEEK 12: 6.8 (SD 4.3); MEAN DIFFERENCE -4.3 (95% CONFIDENCE INTERVAL -1.64 TO -6.7); P<0.001} AND YOGA GROUPS [BASELINE: 12.8 (SD 7.4) VS WEEK 12: 8.1 (SD 5.6); MEAN DIFFERENCE -4.7 (95% CONFIDENCE INTERVAL -2.1 TO -7.4); P<0.00], WITH NO CHANGE IN THE CONTROL GROUP. PAIN RATINGS ALSO IMPROVED SIGNIFICANTLY. MODERATE-TO-LARGE EFFECT SIZES (0.7 TO 1.8) AND LOW NUMBERS NEEDED TO TREAT WERE FOUND. THERE WERE NO DIFFERENCES IN OUTCOMES BETWEEN THE EXERCISE GROUPS OR ASSOCIATED ADVERSE EFFECTS. NO IMPROVEMENTS IN RANGE OF MOVEMENT OR POSTURE WERE FOUND. CONCLUSIONS: PILATES AND YOGA GROUP EXERCISE INTERVENTIONS WITH APPROPRIATE MODIFICATIONS AND SUPERVISION WERE SAFE AND EQUALLY EFFECTIVE FOR DECREASING DISABILITY AND PAIN COMPARED WITH THE CONTROL GROUP FOR INDIVIDUALS WITH MILD-TO-MODERATE CNP. PHYSIOTHERAPISTS MAY CONSIDER INCLUDING THESE APPROACHES IN A PLAN OF CARE. CLINICAL TRIAL REGISTRATION NUMBER: CLINICALTRIALS.GOV NCT01999283.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
9   90  35 A MODIFIED YOGA-BASED EXERCISE PROGRAM IN HEMODIALYSIS PATIENTS: A RANDOMIZED CONTROLLED STUDY. AIM: TO EVALUATE THE EFFECTS OF A YOGA-BASED EXERCISE PROGRAM ON PAIN, FATIGUE, SLEEP DISTURBANCE, AND BIOCHEMICAL MARKERS IN HEMODIALYSIS PATIENTS. MATERIALS AND METHODS: IN 2004 A RANDOMIZED CONTROLLED TRIAL WAS CARRIED OUT IN THE OUTPATIENT HEMODIALYSIS UNIT OF THE NEPHROLOGY DEPARTMENT, ULUDAG UNIVERSITY FACULTY OF MEDICINE. CLINICALLY STABLE HEMODIALYSIS PATIENTS (N=37) WERE INCLUDED AND FOLLOWED IN TWO GROUPS: THE MODIFIED YOGA-BASED EXERCISE GROUP (N=19) AND THE CONTROL GROUP (N=18). YOGA-BASED EXERCISES WERE DONE IN GROUPS FOR 30 MIN/DAY TWICE A WEEK FOR 3 MONTHS. ALL OF THE PATIENTS IN THE YOGA AND CONTROL GROUPS WERE GIVEN AN ACTIVE RANGE OF MOTION EXERCISES TO DO FOR 10 MIN AT HOME. THE MAIN OUTCOME MEASURES WERE PAIN INTENSITY (MEASURED BY THE VISUAL ANALOGUE SCALE, VAS), FATIGUE (VAS), SLEEP DISTURBANCE (VAS), AND GRIP STRENGTH (MMHG); BIOCHEMICAL VARIABLES-- UREA, CREATININE, CALCIUM, ALKALINE PHOSPHATASE, PHOSPHORUS, CHOLESTEROL, HDL-CHOLESTEROL, TRIGLYCERIDE, ERYTHROCYTE, HEMATOCRIT--WERE EVALUATED. RESULTS: AFTER A 12-WEEK INTERVENTION, SIGNIFICANT IMPROVEMENTS WERE SEEN IN THE VARIABLES: PAIN -37%, FATIGUE -55%, SLEEP DISTURBANCE -25%, GRIP STRENGTH +15%, UREA -29%, CREATININE -14%, ALKALINE PHOSPHATASE -15%, CHOLESTEROL -15%, ERYTHROCYTE +11%, AND HEMATOCRIT COUNT +13%; NO SIDE-EFFECTS WERE SEEN. IMPROVEMENT OF THE VARIABLES IN THE YOGA-BASED EXERCISE PROGRAM WAS FOUND TO BE SUPERIOR TO THAT IN THE CONTROL GROUP FOR ALL THE VARIABLES EXCEPT CALCIUM, PHOSPHORUS, HDL-CHOLESTEROL AND TRIGLYCERIDE LEVELS. CONCLUSION: A SIMPLIFIED YOGA-BASED REHABILITATION PROGRAM IS A COMPLEMENTARY, SAFE AND EFFECTIVE CLINICAL TREATMENT MODALITY IN PATIENTS WITH END-STAGE RENAL DISEASE.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
10 2828  38 YOGA VERSUS PHYSICAL EXERCISE FOR CARDIO-RESPIRATORY FITNESS IN ADOLESCENT SCHOOL CHILDREN: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND YOGA IS VERY EFFECTIVE IN IMPROVING HEALTH ESPECIALLY CARDIO-RESPIRATORY FITNESS AND ALSO OVERALL PERFORMANCE IN ADOLESCENTS. THERE ARE NO LARGE NUMBERS OF RANDOMIZED CONTROLLED STUDIES CONDUCTED ON COMPARING YOGA WITH PHYSICAL ACTIVITY FOR CARDIO-RESPIRATORY FITNESS IN ADOLESCENT SCHOOL CHILDREN WITH LARGE SAMPLE SIZE. OBJECTIVE AEROBIC TRAINING IS KNOWN TO IMPROVE PHYSICAL AND CARDIO-RESPIRATORY FITNESS IN CHILDREN. CARDIO-RESPIRATORY FITNESS IS AN IMPORTANT INDICATOR OF HEALTH IN CHILDREN. IN THIS STUDY WE EVALUATE THE EFFECTS OF YOGA VERSUS PHYSICAL EXERCISE TRAINING ON CARDIO-RESPIRATORY FITNESS IN ADOLESCENT SCHOOL CHILDREN. SUBJECTS EIGHT HUNDRED TWO SCHOOL STUDENTS FROM 10 SCHOOLS ACROSS FOUR DISTRICTS WERE RECRUITED FOR THIS STUDY. METHODS IN THIS PROSPECTIVE TWO ARM RCT AROUND 802 STUDENTS WERE RANDOMIZED TO RECEIVE DAILY ONE HOUR YOGA TRAINING (N = 411) OR PHYSICAL EXERCISE (N = 391) OVER A PERIOD OF TWO MONTHS. VO2 MAX WAS ESTIMATED USING 20 M SHUTTLE RUN TEST. HOWEVER, YOGA (N = 377) AND PHYSICAL EXERCISE (N = 371) STUDENTS CONTRIBUTED DATA TO THE ANALYSES. DATA WAS ANALYSED USING STUDENTS T TEST. RESULTS THERE WAS A SIGNIFICANT IMPROVEMENT IN VO2 MAX USING 20 M SHUTTLE RUN TEST IN BOTH YOGA (P < 0.001) AND EXERCISE (P < 0.001) GROUP FOLLOWING INTERVENTION. THERE WAS NO SIGNIFICANT CHANGE IN VO2 MAX BETWEEN YOGA AND PHYSICAL EXERCISE GROUP FOLLOWING INTERVENTION. HOWEVER, IN THE SUBGROUP WITH AN ABOVE MEDIAN CUT-OFF OF VO2 MAX; THERE WAS A SIGNIFICANT IMPROVEMENT IN YOGA GROUP COMPARED TO CONTROL GROUP FOLLOWING INTERVENTION (P = 0.03). CONCLUSION THE RESULTS SUGGEST YOGA CAN IMPROVE CARDIO-RESPIRATORY FITNESS AND AEROBIC CAPACITY AS PHYSICAL EXERCISE INTERVENTION IN ADOLESCENT SCHOOL CHILDREN.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
11  389  34 BENEFITS OF YOGA FOR AFRICAN AMERICAN HEART FAILURE PATIENTS. BACKGROUND: THE NUMBER OF AFRICAN AMERICAN (AA) PATIENTS LIVING WITH HEART FAILURE (HF) HAS BEEN INCREASING, ESPECIALLY AMONG THE ECONOMICALLY DISADVANTAGED. YOGA THERAPY HAS BEEN FOUND TO IMPROVE PHYSICAL AND PSYCHOLOGICAL PARAMETERS AMONG HEALTHY INDIVIDUALS, BUT ITS EFFECT IN PATIENTS WITH HF REMAINS UNKNOWN. THE PURPOSE OF THIS STUDY WAS TO EXAMINE THE EFFECTS OF YOGA THERAPY ON CARDIOVASCULAR ENDURANCE (VO2PEAK), FLEXIBILITY, QUALITY OF LIFE (QOL), AND INFLAMMATORY MARKERS ON MEDICALLY STABLE HF PATIENTS. METHODS: FORTY PATIENTS (38 AA, 1 ASIAN, AND 1 CAUCASIAN) WITH SYSTOLIC OR DIASTOLIC HF WERE RANDOMIZED TO THE YOGA GROUP (YG, N = 21) OR THE CONTROL GROUP (CG, N = 19). ALL PATIENTS WERE ASKED TO FOLLOW A HOME WALK PROGRAM. PREMEASUREMENT AND POSTMEASUREMENT INCLUDED A TREADMILL STRESS TEST TO PEAK EXERTION, FLEXIBILITY, INTERLEUKIN-6 (IL-6), C-REACTIVE PROTEIN (CRP), AND EXTRACELLULAR SUPEROXIDE DISMUTASE (EC-SOD). QOL WAS ASSESSED BY THE MINNESOTA LIVING WITH HEART FAILURE QUESTIONNAIRE (MLWHFQ). RESULTS: THE STATISTICAL ANALYSES (ASSESSED BY ANOVA AND T-TESTS) WERE SIGNIFICANT FOR FAVORABLE CHANGES IN THE YG, COMPARED WITH THOSE IN THE CG, FOR FLEXIBILITY (P = 0.012), TREADMILL TIME (P = 0.002), VO2PEAK (P = 0.003), AND THE BIOMARKERS (IL-6, P = 0.004; CRP, P = 0.016; AND EC-SOD, P = 0.012). WITHIN THE YG, PRETEST TO POSTTEST SCORES FOR THE TOTAL (P = 0.02) AND PHYSICAL SUBSCALES (P < 0.001) OF THE MLWHFQ WERE IMPROVED. CONCLUSIONS: YOGA THERAPY OFFERED ADDITIONAL BENEFITS TO THE STANDARD MEDICAL CARE OF PREDOMINANTLY AA HF PATIENTS BY IMPROVING CARDIOVASCULAR ENDURANCE, QOL, INFLAMMATORY MARKERS, AND FLEXIBILITY.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
12   34  34 A 12-WEEK IYENGAR YOGA PROGRAM IMPROVED BALANCE AND MOBILITY IN OLDER COMMUNITY-DWELLING PEOPLE: A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: EXERCISE THAT CHALLENGES BALANCE CAN IMPROVE MOBILITY AND PREVENT FALLS IN OLDER ADULTS. YOGA AS A PHYSICAL ACTIVITY OPTION FOR OLDER ADULTS IS NOT WELL STUDIED. THIS TRIAL EVALUATED THE FEASIBILITY AND EFFECT OF A 12-WEEK IYENGAR YOGA PROGRAM ON BALANCE AND MOBILITY IN OLDER PEOPLE. METHODS: WE CONDUCTED A BLINDED, PILOT RANDOMIZED CONTROLLED TRIAL WITH INTENTION-TO-TREAT ANALYSIS. PARTICIPANTS WERE 54 COMMUNITY DWELLERS (MEAN AGE 68 YEARS, SD 7.1) NOT CURRENTLY PARTICIPATING IN YOGA OR TAI CHI. THE INTERVENTION GROUP (N = 27) PARTICIPATED IN A 12-WEEK, TWICE-WEEKLY YOGA PROGRAM FOCUSED ON STANDING POSTURES AND RECEIVED A FALL PREVENTION EDUCATION BOOKLET. THE CONTROL GROUP (N = 27) RECEIVED THE EDUCATION BOOKLET ONLY. PRIMARY OUTCOME WAS STANDING BALANCE COMPONENT OF THE SHORT PHYSICAL PERFORMANCE BATTERY WITH ADDITION OF ONE-LEGGED STANCE TIME (STANDING BALANCE). SECONDARY OUTCOMES WERE THE TIMED SIT-TO-STAND TEST, TIMED 4-M WALK, ONE-LEGGED STAND WITH EYES CLOSED, AND SHORT FALLS EFFICACY SCALE-INTERNATIONAL. FEASIBILITY WAS MEASURED BY RECORDING CLASS ATTENDANCE AND ADVERSE EVENTS. RESULTS: FIFTY-TWO PARTICIPANTS COMPLETED FOLLOW-UP ASSESSMENTS. THE INTERVENTION GROUP SIGNIFICANTLY IMPROVED COMPARED WITH CONTROL GROUP ON STANDING BALANCE (MEAN DIFFERENCE = 1.52 SECONDS, 95% CI 0.10-2.96, P = .04), SIT-TO-STAND TEST (MEAN DIFFERENCE = -3.43 SECONDS, 95% CI -5.23 TO -1.64, P < .001), 4-M WALK (MEAN DIFFERENCE = -0.50 SECONDS, 95% CI -0.72 TO -0.28, P < .001), AND ONE-LEGGED STAND WITH EYES CLOSED (MEAN DIFFERENCE = 1.93 SECONDS, 95% CI 0.40-3.46, P = .02). AVERAGE CLASS ATTENDANCE WAS 20 OF 24 CLASSES (83%). NO SERIOUS ADVERSE EVENTS OCCURRED. CONCLUSIONS: THIS TRIAL DEMONSTRATES THE BALANCE AND MOBILITY-RELATED BENEFITS AND FEASIBILITY OF IYENGAR YOGA FOR OLDER PEOPLE. THE FALL PREVENTION EFFECT OF IYENGAR YOGA WARRANTS FURTHER INVESTIGATION.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
13  995  33 EFFECTS OF HIGH-INTENSITY HATHA YOGA ON CARDIOVASCULAR FITNESS, ADIPOCYTOKINES, AND APOLIPOPROTEINS IN HEALTHY STUDENTS: A RANDOMIZED CONTROLLED STUDY. BACKGROUND: YOGA EXERCISES ARE OFTEN USED AS A FORM OF BODY AND MIND EXERCISE TO INCREASE PERFORMANCE. HOWEVER, KNOWLEDGE ABOUT THE PHYSIOLOGIC EFFECTS OF PERFORMING HIGH-INTENSITY HATHA YOGA EXERCISES OVER A LONGER TIME PERIOD REMAINS LIMITED. OBJECTIVE: TO INVESTIGATE THE EFFECTS OF HIGH-INTENSITY YOGA (HIY) ON CARDIOVASCULAR FITNESS (MAXIMAL OXYGEN CONSUMPTION, ESTIMATED FROM THE COOPER RUNNING TEST), RATINGS OF PERCEIVED EXERTION (RPE), HEART RATE (HR), HEART RATE RECOVERY (HRR), BLOOD PRESSURE (BP), ADIPOCYTOKINES, APOLIPOPROTEIN A1 (APOA1), APOLIPOPROTEIN B (APOB), AND GLYCOSYLATED HEMOGLOBIN (HBA1C) IN HEALTHY STUDENTS. METHODS: THE 44 PARTICIPANTS (38 WOMEN AND 6 MEN; MEDIAN AGE, 25 YEARS [RANGE, 20-39 YEARS]) WERE RANDOMLY ASSIGNED TO AN HIY OR A CONTROL GROUP. THE HIY PROGRAM WAS HELD FOR 6 WEEKS (60 MINUTES ONCE A WEEK). CARDIOVASCULAR FITNESS, RPE, HR, HRR, BP, ADIPOCYTOKINES, HBA1C, APOA1, AND APOB WERE MEASURED AT BASELINE AND AFTER 6 WEEKS IN BOTH GROUPS. RESULTS: HIY HAD NO SIGNIFICANT EFFECTS ON CARDIOVASCULAR FITNESS (MEAN DOSE: 390 MINUTES [RANGE, 210-800 MINUTES]), HR, HRR, BP, OR ANY OF THE BLOOD PARAMETERS. HOWEVER, SECONDARY FINDINGS SHOWED THAT [CORRECTED] APOA1 (1.47 +/- 0.17 TO 1.55 +/- 0.16 G/L; P = 0.03) AND ADIPONECTIN (8.32 +/- 3.32 TO 9.68 +/- 3.83 MG/L; P = 0.003) LEVELS INCREASED SIGNIFICANTLY IN THE HIY GROUP AFTER 6 WEEKS. CONCLUSIONS: SIX WEEKS OF HIY DID NOT SIGNIFICANTLY IMPROVE CARDIOVASCULAR FITNESS. HOWEVER, SECONDARY FINDINGS SHOWED THAT [CORRECTED] APOA1 AND ADIPONECTIN LEVELS INCREASED SIGNIFICANTLY IN THE HIY GROUP. THIS FINDING SUGGESTS THAT HIY MAY HAVE POSITIVE EFFECTS ON BLOOD LIPIDS AND AN ANTI-INFLAMMATORY EFFECT.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
14 2507  31 YOGA BASED CARDIAC REHABILITATION AFTER CORONARY ARTERY BYPASS SURGERY: ONE-YEAR RESULTS ON LVEF, LIPID PROFILE AND PSYCHOLOGICAL STATES--A RANDOMIZED CONTROLLED STUDY. OBJECTIVE: TO COMPARE THE LONG TERM EFFECTS OF YOGA BASED CARDIAC REHABILITATION PROGRAM WITH ONLY PHYSIOTHERAPY BASED PROGRAM AS AN ADD-ON TO CONVENTIONAL REHABILITATION AFTER CORONARY ARTERY BYPASS GRAFTING (CABG) ON RISK FACTORS. METHODS: IN THIS SINGLE BLIND PROSPECTIVE RANDOMIZED PARALLEL TWO ARMED ACTIVE CONTROL STUDY, 1026 PATIENTS POSTED FOR CABG AT NARAYANA HRUDAYALAYA INSTITUTE OF CARDIAC SCIENCES, BENGALURU (INDIA) WERE SCREENED. OF THESE, 250 MALE PARTICIPANTS (35-65 YEARS) WHO SATISFIED THE SELECTION CRITERIA AND CONSENTED WERE RANDOMIZED INTO TWO GROUPS. WITHIN AND BETWEEN GROUP COMPARISONS WERE DONE AT THREE POINTS OF FOLLOW UP (I.E. 6TH WEEK, 6TH MONTH, AND 12TH MONTH) BY USING WILCOXON'S SIGNED RANKS TEST AND MANN WHITNEY U TEST RESPECTIVELY. RESULTS: YOGA GROUP HAD SIGNIFICANTLY (P = 0.001, MANN WHITNEY) BETTER IMPROVEMENT IN LVEF THAN CONTROL GROUP IN THOSE WITH ABNORMAL BASELINE EF (<53%) AFTER 1 YEAR. THERE WAS A BETTER REDUCTION IN BMI IN THE YOGA GROUP (P = 0.038, BETWEEN GROUPS) IN THOSE WITH HIGH BASELINE BMI (>/=23) AFTER 12 MONTHS. YOGA GROUP SHOWED SIGNIFICANT (P = 0.008, WILCOXON'S) REDUCTION IN BLOOD GLUCOSE AT ONE YEAR IN THOSE WITH HIGH BASELINE FBS >/=110 MG/DL. THERE WAS SIGNIFICANTLY BETTER IMPROVEMENT IN YOGA THAN THE CONTROL GROUP IN HDL (P = 0.003), LDL (P = 0.01) AND VLDL (P = 0.03) IN THOSE WITH ABNORMAL BASELINE VALUES. THERE WAS SIGNIFICANTLY BETTER IMPROVEMENT (P = 0.02, BETWEEN GROUPS) IN POSITIVE AFFECT IN YOGA GROUP. WITHIN YOGA GROUP, THERE WAS SIGNIFICANT DECREASE IN PERCEIVED STRESS (P = 0.001), ANXIETY (P = 0.001), DEPRESSION (P = 0.001), AND NEGATIVE AFFECT (P = 0.03) WHILE IN THE CONTROL GROUP THERE WAS REDUCTION (P = 0.003) ONLY IN SCORES ON ANXIETY. CONCLUSION: ADDITION OF YOGA BASED RELAXATION TO CONVENTIONAL POST-CABG CARDIAC REHABILITATION HELPS IN BETTER MANAGEMENT OF RISK FACTORS IN THOSE WITH ABNORMAL BASELINE VALUES AND MAY HELP IN PREVENTING RECURRENCE.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
15 1859  35 RANDOMIZED CONTROLLED PILOT TRIAL OF YOGA IN OVERWEIGHT AND OBESE BREAST CANCER SURVIVORS: EFFECTS ON QUALITY OF LIFE AND ANTHROPOMETRIC MEASURES. PURPOSE: TO OBTAIN ESTIMATES OF TIME TO RECRUIT THE STUDY SAMPLE, RETENTION, FACILITY-BASED CLASS ATTENDANCE AND HOME PRACTICE FOR A STUDY OF YOGA IN BREAST CANCER SURVIVORS, AND ITS EFFICACY ON FATIGUE, QUALITY OF LIFE (QOL), AND WEIGHT CHANGE. METHODS: SIXTY-THREE POST-TREATMENT STAGES 0-III BORDERLINE OVERWEIGHT AND OBESE (BODY MASS INDEX >/= 24 KG/M(2)) BREAST CANCER SURVIVORS WERE RANDOMLY ASSIGNED TO A 6-MONTH, FACILITY- AND HOME-BASED VINIYOGA INTERVENTION (N = 32) OR A WAITLIST CONTROL GROUP (N = 31). THE YOGA GOAL WAS FIVE PRACTICES PER WEEK. PRIMARY OUTCOME MEASURES WERE CHANGES IN QOL, FATIGUE, AND WEIGHT FROM BASELINE TO 6 MONTHS. SECONDARY OUTCOMES INCLUDED CHANGES IN WAIST AND HIP CIRCUMFERENCE. RESULTS: IT TOOK 12 MONTHS TO COMPLETE RECRUITMENT. PARTICIPANTS ATTENDED A MEAN OF 19.6 CLASSES AND PRACTICED AT HOME A MEAN OF 55.8 TIMES DURING THE 6-MONTH PERIOD. AT FOLLOW-UP, 90% OF PARTICIPANTS COMPLETED QUESTIONNAIRES AND 87% COMPLETED ANTHROPOMETRIC MEASUREMENTS. QOL AND FATIGUE IMPROVED TO A GREATER EXTENT AMONG WOMEN IN THE YOGA GROUP RELATIVE TO WOMEN IN THE CONTROL GROUP, ALTHOUGH NO DIFFERENCES WERE STATISTICALLY SIGNIFICANT. WAIST CIRCUMFERENCE DECREASED 3.1 CM (95% CI, -5.7 AND -0.4) MORE AMONG WOMEN IN THE YOGA COMPARED WITH THE CONTROL GROUP, WITH NO DIFFERENCE IN WEIGHT CHANGE. CONCLUSIONS: THIS STUDY PROVIDES IMPORTANT INFORMATION REGARDING RECRUITMENT, RETENTION, AND PRACTICE LEVELS ACHIEVED DURING A 6-MONTH, INTENSIVE YOGA INTERVENTION IN OVERWEIGHT AND OBESE BREAST CANCER SURVIVORS. YOGA MAY HELP DECREASE WAIST CIRCUMFERENCE AND IMPROVE QUALITY OF LIFE; FUTURE STUDIES ARE NEEDED TO CONFIRM THESE RESULTS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
16  944  26 EFFECTS OF A 12-WEEK HATHA YOGA INTERVENTION ON METABOLIC RISK AND QUALITY OF LIFE IN HONG KONG CHINESE ADULTS WITH AND WITHOUT METABOLIC SYNDROME. OBJECTIVE: TO DETERMINE THE EFFICACY OF A 12-WEEK HATHA YOGA INTERVENTION TO IMPROVE METABOLIC RISK PROFILES AND HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN CHINESE ADULTS WITH AND WITHOUT METABOLIC SYNDROME (METS). METHODS: WE CONDUCTED A CONTROLLED TRIAL WITHIN AN UNIVERSITY-AFFILIATED HOSPITAL. 173 CHINESE MEN AND WOMEN AGED 18 OR ABOVE WERE ASSIGNED TO EITHER THE YOGA INTERVENTION GROUP (N = 87) OR THE CONTROL GROUP (N = 86). PRIMARY OUTCOMES INCLUDED 12-WEEK CHANGE IN METABOLIC RISK FACTORS AND METS Z SCORE. SECONDARY OUTCOME WAS HRQOL (MEDICAL OUTCOMES SHORT FORM SURVEY AT 12 WEEKS). RESULTS: THE MEAN AGE OF PARTICIPANTS WAS 52.0 (SD 7.4, RANGE 31-71) YEARS. ANALYSIS INVOLVING THE ENTIRE STUDY POPULATION REVEALED THAT THE YOGA GROUP ACHIEVED GREATER DECLINE IN WAIST CIRCUMFERENCE (P<0.001), FASTING GLUCOSE (P<0.01), TRIGLYCERIDES (P<0.05), AND METS Z SCORE (P<0.01). YOGA TRAINING ALSO IMPROVED GENERAL HEALTH PERCEPTIONS (P<0.01), PHYSICAL COMPONENT SCORE (P<0.01), AND SOCIAL FUNCTIONING (P<0.01) DOMAINS SCORE OF HRQOL. HOWEVER, NO SIGNIFICANT DIFFERENCES BETWEEN GROUPS WERE OBSERVED IN THE MEAN CHANGE OF SYSTOLIC/DIASTOLIC BLOOD PRESSURES OR HIGH-DENSITY LIPID PROTEIN CHOLESTEROL (ALL P>0.05). THERE WERE NO SIGNIFICANT DIFFERENCES IN THE INTERVENTION EFFECTS ON WAIST CIRCUMFERENCE AND METS Z SCORE BETWEEN THE METS SUBGROUPS (BOTH P>0.05). CONCLUSION: A 12-WEEK HATHA YOGA INTERVENTION IMPROVES METABOLIC RISK PROFILES AND HRQOL IN CHINESE ADULTS WITH AND WITHOUT METS. TRIAL REGISTRATION: AUSTRALIAN NEW ZEALAND CLINICAL TRIALS REGISTRY ACTRN12613000816752.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
17  993  13 EFFECTS OF HEATED AND THERMONEUTRAL YOGA INTERVENTIONS ON ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS. THE STUDY INVESTIGATED THE EFFICACY OF 12 WEEKS OF HEATED AND THERMONEUTRAL BIKRAM YOGA IN REDUCING ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS. FIFTY-FOUR SEDENTARY ADULTS (AGES 40-60 YEARS) COMPLETED 12 WEEKS OF YOGA AT 40.5 DEGREES C (N = 21), YOGA AT 23 DEGREES C (N = 14) OR TIME CONTROL (N = 19). BRACHIAL-ANKLE PULSE WAVE VELOCITY (PWV) WAS NOT SIGNIFICANTLY ALTERED BY HOT OR THERMONEUTRAL YOGA INTERVENTIONS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
18  668  38 EFFECT OF A 16-WEEK BIKRAM YOGA PROGRAM ON HEART RATE VARIABILITY AND ASSOCIATED CARDIOVASCULAR DISEASE RISK FACTORS IN STRESSED AND SEDENTARY ADULTS: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: CHRONIC ACTIVATION OF THE STRESS-RESPONSE CAN CONTRIBUTE TO CARDIOVASCULAR DISEASE RISK, PARTICULARLY IN SEDENTARY INDIVIDUALS. THIS STUDY INVESTIGATED THE EFFECT OF A BIKRAM YOGA INTERVENTION ON THE HIGH FREQUENCY POWER COMPONENT OF HEART RATE VARIABILITY (HRV) AND ASSOCIATED CARDIOVASCULAR DISEASE (CVD) RISK FACTORS (I.E. ADDITIONAL DOMAINS OF HRV, HEMODYNAMIC, HEMATOLOGIC, ANTHROPOMETRIC AND BODY COMPOSITION OUTCOME MEASURES) IN STRESSED AND SEDENTARY ADULTS. METHODS: ELIGIBLE ADULTS WERE RANDOMIZED TO AN EXPERIMENTAL GROUP (N = 29) OR A NO TREATMENT CONTROL GROUP (N = 34). EXPERIMENTAL GROUP PARTICIPANTS WERE INSTRUCTED TO ATTEND THREE TO FIVE SUPERVISED BIKRAM YOGA CLASSES PER WEEK FOR 16 WEEKS AT LOCAL STUDIOS. OUTCOME MEASURES WERE ASSESSED AT BASELINE (WEEK 0) AND COMPLETION (WEEK 17). RESULTS: SIXTY-THREE ADULTS (37.2 +/- 10.8 YEARS, 79% WOMEN) WERE INCLUDED IN THE INTENTION-TO-TREAT ANALYSIS. THE EXPERIMENTAL GROUP ATTENDED 27 +/- 18 CLASSES. ANALYSES OF COVARIANCE REVEALED NO SIGNIFICANT CHANGE IN THE HIGH-FREQUENCY COMPONENT OF HRV (P = 0.912, PARTIAL ETA (2) = 0.000) OR IN ANY SECONDARY OUTCOME MEASURE BETWEEN GROUPS OVER TIME. HOWEVER, REGRESSION ANALYSES REVEALED THAT HIGHER ATTENDANCE IN THE EXPERIMENTAL GROUP WAS ASSOCIATED WITH SIGNIFICANT REDUCTIONS IN DIASTOLIC BLOOD PRESSURE (P = 0.039; PARTIAL ETA (2) = 0.154), BODY FAT PERCENTAGE (P = 0.001, PARTIAL ETA (2) = 0.379), FAT MASS (P = 0.003, PARTIAL ETA (2) = 0.294) AND BODY MASS INDEX (P = 0.05, PARTIAL ETA (2) = 0.139). CONCLUSIONS: A 16-WEEK BIKRAM YOGA PROGRAM DID NOT INCREASE THE HIGH FREQUENCY POWER COMPONENT OF HRV OR ANY OTHER CVD RISK FACTORS INVESTIGATED. AS REVEALED BY POST HOC ANALYSES, LOW ADHERENCE LIKELY CONTRIBUTED TO THE NULL EFFECTS. FUTURE STUDIES ARE REQUIRED TO ADDRESS BARRIERS TO ADHERENCE TO BETTER ELUCIDATE THE DOSE-RESPONSE EFFECTS OF BIKRAM YOGA PRACTICE AS A MEDIUM TO LOWER STRESS-RELATED CVD RISK. TRIAL REGISTRATION: RETROSPECTIVELY REGISTERED WITH AUSTRALIA NEW ZEALAND CLINICAL TRIALS REGISTRY ACTRN12616000867493 . REGISTERED 04 JULY 2016.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
19 1133  30 EFFICACY OF YOGA FOR VASOMOTOR SYMPTOMS: A RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: THIS STUDY AIMS TO DETERMINE THE EFFICACY OF YOGA IN ALLEVIATING VASOMOTOR SYMPTOMS (VMS) FREQUENCY AND BOTHER. METHODS: THIS STUDY WAS A THREE-BY-TWO FACTORIAL, RANDOMIZED CONTROLLED TRIAL. ELIGIBLE WOMEN WERE RANDOMIZED TO YOGA (N = 107), EXERCISE (N = 106), OR USUAL ACTIVITY (N = 142), AND WERE SIMULTANEOUSLY RANDOMIZED TO A DOUBLE-BLIND COMPARISON OF OMEGA-3 FATTY ACID (N = 177) OR PLACEBO (N = 178) CAPSULES. YOGA INTERVENTION CONSISTED OF 12 WEEKLY 90-MINUTE YOGA CLASSES WITH DAILY HOME PRACTICE. PRIMARY OUTCOMES WERE VMS FREQUENCY AND BOTHER ASSESSED BY DAILY DIARIES AT BASELINE, 6 WEEKS, AND 12 WEEKS. SECONDARY OUTCOMES INCLUDED INSOMNIA SYMPTOMS (INSOMNIA SEVERITY INDEX) AT BASELINE AND 12 WEEKS. RESULTS: AMONG 249 RANDOMIZED WOMEN, 237 (95%) COMPLETED 12-WEEK ASSESSMENTS. THE MEAN BASELINE VMS FREQUENCY WAS 7.4 PER DAY (95% CI, 6.6 TO 8.1) IN THE YOGA GROUP AND 8.0 PER DAY (95% CI, 7.3 TO 8.7) IN THE USUAL ACTIVITY GROUP. INTENT-TO-TREAT ANALYSES INCLUDED ALL PARTICIPANTS WITH RESPONSE DATA (N = 237). THERE WAS NO DIFFERENCE BETWEEN INTERVENTION GROUPS IN THE CHANGE IN VMS FREQUENCY FROM BASELINE TO 6 AND 12 WEEKS (MEAN DIFFERENCE [YOGA--USUAL ACTIVITY] FROM BASELINE AT 6 WK, -0.3 [95% CI, -1.1 TO 0.5]; MEAN DIFFERENCE [YOGA--USUAL ACTIVITY] FROM BASELINE AT 12 WK, -0.3 [95% CI, -1.2 TO 0.6]; P = 0.119 ACROSS BOTH TIME POINTS). RESULTS WERE SIMILAR FOR VMS BOTHER. AT WEEK 12, YOGA WAS ASSOCIATED WITH AN IMPROVEMENT IN INSOMNIA SYMPTOMS (MEAN DIFFERENCE [YOGA - USUAL ACTIVITY] IN THE CHANGE IN INSOMNIA SEVERITY INDEX, 1.3 [95% CI, -2.5 TO -0.1]; P = 0.007). CONCLUSIONS: AMONG HEALTHY WOMEN, 12 WEEKS OF YOGA CLASS PLUS HOME PRACTICE, COMPARED WITH USUAL ACTIVITY, DO NOT IMPROVE VMS FREQUENCY OR BOTHER BUT REDUCE INSOMNIA SYMPTOMS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
20 1194  28 EXAMINING MEDIATORS AND MODERATORS OF YOGA FOR WOMEN WITH BREAST CANCER UNDERGOING RADIOTHERAPY. HYPOTHESIS THIS STUDY EXAMINES MODERATORS AND MEDIATORS OF A YOGA INTERVENTION TARGETING QUALITY-OF-LIFE (QOL) OUTCOMES IN WOMEN WITH BREAST CANCER RECEIVING RADIOTHERAPY.METHODS WOMEN UNDERGOING 6 WEEKS OF RADIOTHERAPY WERE RANDOMIZED TO A YOGA (YG; N = 53) OR STRETCHING (ST; N = 56) INTERVENTION OR A WAITLIST CONTROL GROUP (WL; N = 54). DEPRESSIVE SYMPTOMS AND SLEEP DISTURBANCES WERE MEASURED AT BASELINE. MEDIATOR (POSTTRAUMATIC STRESS SYMPTOMS, BENEFIT FINDING, AND CORTISOL SLOPE) AND OUTCOME (36-ITEM SHORT FORM [SF]-36 MENTAL AND PHYSICAL COMPONENT SCALES [MCS AND PCS]) VARIABLES WERE ASSESSED AT BASELINE, END-OF-TREATMENT, AND 1-, 3-, AND 6-MONTHS POSTTREATMENT. RESULTS BASELINE DEPRESSIVE SYMPTOMS (P = .03) AND SLEEP DISTURBANCES (P < .01) MODERATED THE GROUP X TIME EFFECT ON MCS, BUT NOT PCS. WOMEN WITH HIGH BASELINE DEPRESSIVE SYMPTOMS IN YG REPORTED MARGINALLY HIGHER 3-MONTH MCS THAN THEIR COUNTERPARTS IN WL (P = .11). WOMEN WITH HIGH BASELINE SLEEP DISTURBANCES IN YG REPORTED HIGHER 3-MONTHS MCS THAN THEIR COUNTERPARTS IN WL (P < .01) AND HIGHER 6-MONTH MCS THAN THEIR COUNTERPARTS IN ST (P = .01). YG LED TO GREATER BENEFIT FINDING THAN ST AND WL ACROSS THE FOLLOW-UP (P = .01). THREE-MONTH BENEFIT FINDING PARTIALLY MEDIATED THE EFFECT OF YG ON 6-MONTH PCS. POSTTRAUMATIC STRESS SYMPTOMS AND CORTISOL SLOPE DID NOT MEDIATE TREATMENT EFFECT ON QOL. CONCLUSION YOGA MAY PROVIDE THE GREATEST MENTAL-HEALTH-RELATED QOL BENEFITS FOR THOSE EXPERIENCING PRE-RADIOTHERAPY SLEEP DISTURBANCE AND DEPRESSIVE SYMPTOMS. YOGA MAY IMPROVE PHYSICAL-HEALTH-RELATED QOL BY INCREASING ABILITY TO FIND BENEFIT IN THE CANCER EXPERIENCE.	2016