1 1231 187 FEASIBILITY AND PILOT EFFICACY TESTING OF INTEGRATED YOGA AND SHIRODHARA (AYURVEDIC OIL-DRIPPING) INTERVENTION ON CLINICAL SYMPTOMS, COGNITIVE FUNCTIONS AND SLEEP QUALITY OF ADULTS WITH ANXIETY DISORDER. BACKGROUND: BENEFICIAL EFFECTS OF YOGA THERAPY IN ANXIETY DISORDERS (ADS) ARE KNOWN. TRADITIONAL TEXTS DESCRIBE USEFULNESS OF AYURVEDIC OIL-DRIPPING, SHIRODHARA TECHNIQUE, IN RELIEVING ANXIETY. THUS, PRESENT STUDY WAS PLANNED TO ASSESS THE FEASIBILITY AND SYNERGISTIC VALUE OF SHIRODHARA AS AN ADD-ON TO YOGA THERAPY IN ADULTS WITH AD. MATERIALS AND METHODS: THIRTY ADULTS (MALES = 14, FEMALES = 16) ADMITTED IN A RESIDENTIAL HOLISTIC HEALTH CARE CENTER WITH AN AGE RANGE OF 29.66 +/- 6.63 YEARS AND DIAGNOSIS OF ONE OF THE ADS (GENERALIZED AD, N = 18; SOCIAL PHOBIA, N = 8; AND PANIC AD, N = 4) AS PER MINI-INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW (M. I. N. I. ENGLISH VERSION 5.0) BY A PSYCHIATRIST WERE RANDOMLY DIVIDED INTO TWO GROUPS: (1) INTEGRATED YOGA-BASED LIFESTYLE PROGRAM (YT; N = 15) AND (2) YT + AYURVEDA (YA; N = 15). BOTH GROUPS CONTINUED TO RECEIVE CONVENTIONAL TREATMENT AND WERE ON STABLE MEDICATIONS THROUGHOUT THE STUDY PERIOD EXCEPT IN CASES OF EMERGENCY. ASSESSMENTS WERE DONE BY AN INDEPENDENT ASSESSOR AT BASELINE AND AFTER 2 WEEKS OF INTERVENTION FOR CLINICAL SYMPTOMS (HAM-A, STATE AND TRAIT ANXIETY INVENTORY, AND BRIEF PSYCHIATRIC RATING SCALE), SLEEP QUALITY (SLEEP RATING QUESTIONNAIRE), AND COGNITION (STROOP TEST AND DIGIT LETTER SUBSTITUTION TEST) USING STANDARD VALIDATED TOOLS. PARAMETRIC TESTS WERE APPLIED USING SPSS 10.0 TO ANALYZE THE DATA. RESULTS: TWELVE SUBJECTS IN YOGA GROUP AND THIRTEEN SUBJECTS IN YA GROUP COMPLETED THE TRIAL. NO SIDE EFFECTS WERE REPORTED IN ANY OF THE GROUPS. WITHIN-GROUP COMPARISONS SHOWED A SIGNIFICANT IMPROVEMENT IN CLINICAL SYMPTOMS, COGNITION AND SLEEP QUALITY IN BOTH THE GROUPS. BETWEEN-GROUP COMPARISONS SHOWED SIGNIFICANTLY BETTER SCORES IN STROOP WORD TASK FOR YA GROUP AS COMPARED TO YT GROUP. FURTHERMORE, THERE WAS A TREND TOWARD BETTER IMPROVEMENT IN SLEEP QUALITY FOR YA GROUP. CONCLUSION: ADDING OF SHIRODHARA TECHNIQUE TO YT WAS FEASIBLE AND MAY BE USEFUL IN IMPROVING EXECUTIVE MEMORY AND SLEEP QUALITY IN ADULTS WITH ADS.	2020	
                                                                                                                                                                  
2 1891  27 RELATIONSHIP BETWEEN THE PATIENT'S ATTITUDE TOWARDS YOGA AND THE TREATMENT OUTCOME. CORRELATIONS WERE OBTAINED BETWEEN SCORES ON THE P.G.I. YOGA ATTITUDE SCALE AND IMPROVEMENT IN A GROUP OF 20 PSYCHONEUROTIC PATIENTS UNDERTAKING YOGA THERAPY OF 4-6 WEEKS DURATION. A SIGNIFICANT POSITIVE CORRELATION WAS FOUND BETWEEN THE IMPROVEMENT IN SOCIAL AND VOCATIONAL DISABILITY AND SCORES ON THE P.G.I YOGA ATTITUDE SCALE AT INTAKE. HOWEVER, DURING TREATMENT AND FOLLOWUP, THERE WAS A SIGNIFICANT CHANGE IN THE ATTITUDE TOWARDS YOGA - IT BECAME MORE POSITIVE. CORRELATIONS WERE ALSO PERFORMED BETWEEN IMPROVEMENT AND CHANGE IN ATTITUDE OVER THE 5-MONTH STUDY PERIOD. SIGNIFICANT POSITIVE CORRELATION WAS SEEN ONLY ON PERSONAL DISTRESS. IMPROVEMENT IN THE OTHER SYMPTOMS OF NEUROSIS I.E. ANXIETY, DEPRESSION, MUSCULO-CUTANEOUS FEATURES, VEGETATIVE SYMPTOMS OF NEUROSIS I.E. ANXIETY, DEPRESSION, MUSCULO-CUTANEOUS FEATURES, VEGETATIVE SYMPTOMS AND THE OTHER NEUROTIC FEATURES I.E. HYSTERIA, HYPOCHONDRIASIS, OBSESSIONS-COMPULSIONS AND PHOBIA DID NOT SHOW ANY RELATIONSHIP WITH THE PATIENT'S ATTITUDE TOWARDS YOGA.	1987	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
3  875  51 EFFECT OF YOGA THERAPY ON PLASMA OXYTOCIN AND FACIAL EMOTION RECOGNITION DEFICITS IN PATIENTS OF SCHIZOPHRENIA. CONTEXT: YOGA THERAPY HAS BEEN DEMONSTRATED TO BE USEFUL IN TREATMENT OF NEGATIVE SYMPTOMS AND IMPROVING THE SOCIO-OCCUPATIONAL FUNCTIONING AND EMOTION RECOGNITION DEFICITS IN ANTIPSYCHOTIC-STABILIZED SCHIZOPHRENIA PATIENTS. OXYTOCIN HAS BEEN RECENTLY IMPLICATED IN SOCIAL COGNITION DEFICITS IN SCHIZOPHRENIA. THE EFFECT OF YOGA THERAPY ON OXYTOCIN LEVELS IN SCHIZOPHRENIA HAS NOT BEEN STUDIED. AIMS: THIS STUDY AIMED TO ASSESS THE EFFECT OF YOGA THERAPY ON SYMPTOMS, SOCIO-OCCUPATIONAL FUNCTIONING, FACIAL EMOTION RECOGNITION DEFICITS AND PLASMA OXYTOCIN LEVELS IN ANTIPSYCHOTIC STABILIZED SCHIZOPHRENIA PATIENTS. SETTINGS AND DESIGN: RANDOMIZED CONTROLLED STUDY ON 43 CONSENTING, MEDICATION STABILIZED PATIENTS WITH SCHIZOPHRENIA IN A TERTIARY PSYCHIATRIC CENTER USING YOGA INTERVENTION AND WAITLISTED GROUPS. MATERIALS AND METHODS: A TOTAL OF 43 SCHIZOPHRENIA PATIENTS WERE RANDOMIZED TO YOGA GROUP (N=15) OR WAITLIST GROUP (N=28). PATIENTS IN THE YOGA GROUP RECEIVED TRAINING IN A SPECIFIC YOGA THERAPY MODULE FOR SCHIZOPHRENIA. PATIENTS IN BOTH GROUPS WERE CONTINUED ON STABLE ANTIPSYCHOTIC MEDICATION. ASSESSMENTS INCLUDED SCALE FOR ASSESSMENT OF POSITIVE SYMPTOMS, SCALE FOR ASSESSMENT OF NEGATIVE SYMPTOMS, SOCIO-OCCUPATIONAL FUNCTIONING SCALE AND TOOL FOR RECOGNITION OF EMOTIONS IN NEUROPSYCHIATRIC DISORDERS (TRENDS) AND PLASMA OXYTOCIN LEVELS; PERFORMED AT BASELINE AND AT THE END OF 1 MONTH. RESULTS: A TOTAL OF 15 PATIENTS IN THE YOGA GROUP AND 12 IN WAITLIST GROUP COMPLETED THE STUDY. THE YOGA THERAPY GROUP SHOWED A SIGNIFICANT IMPROVEMENT IN SOCIO-OCCUPATIONAL FUNCTIONING, PERFORMANCE ON TRENDS (P<0.001) AND PLASMA INCREASE IN OXYTOCIN LEVELS (P=0.01) AS COMPARED WITH THE WAITLIST GROUP. CONCLUSION: THE STUDY SUPPORTED THE ROLE OF ADD-ON YOGA THERAPY IN MANAGEMENT OF SCHIZOPHRENIA AND DEMONSTRATED AN IMPROVEMENT IN ENDOGENOUS PLASMA OXYTOCIN LEVELS IN SCHIZOPHRENIA PATIENTS RECEIVING YOGA THERAPY.	2013	
                                                                                                                                                                                                                                                                                                                                                     
4  872  41 EFFECT OF YOGA THERAPY ON FACIAL EMOTION RECOGNITION DEFICITS, SYMPTOMS AND FUNCTIONING IN PATIENTS WITH SCHIZOPHRENIA. OBJECTIVE: FACIAL EMOTION RECOGNITION DEFICITS HAVE BEEN CONSISTENTLY DEMONSTRATED IN SCHIZOPHRENIA AND CAN IMPAIR SOCIO-OCCUPATIONAL FUNCTIONING IN THESE PATIENTS. TREATMENTS TO IMPROVE THESE DEFICITS IN ANTIPSYCHOTIC-STABILIZED PATIENTS HAVE NOT BEEN WELL STUDIED. YOGA THERAPY HAS BEEN DESCRIBED TO IMPROVE FUNCTIONING IN VARIOUS DOMAINS IN SCHIZOPHRENIA; HOWEVER, ITS EFFECT ON FERD IS NOT KNOWN. METHOD: ANTIPSYCHOTIC-STABILIZED PATIENTS RANDOMIZED TO RECEIVE YOGA (N=27), EXERCISE (N=17) OR WAITLIST GROUP (N=22) WERE ASSESSED AT BASELINE, 2ND MONTH, AND 4TH MONTH OF FOLLOW-UP BY RATERS BLIND TO GROUP STATUS. ASSESSMENTS INCLUDED POSITIVE AND NEGATIVE SYNDROME SCALE (PANSS), SOCIO-OCCUPATIONAL FUNCTIONING SCALE (SOFS), AND TOOL FOR RECOGNITION OF EMOTIONS IN NEUROPSYCHIATRIC DISORDERS (TRENDS). RESULTS: THERE WAS A SIGNIFICANT POSITIVE CORRELATION BETWEEN BASELINE FERD AND SOCIO-OCCUPATIONAL FUNCTIONING (R=0.3, P=0.01). PAIRED SAMPLES T TEST SHOWED SIGNIFICANT IMPROVEMENT IN POSITIVE AND NEGATIVE SYMPTOMS, SOCIO-OCCUPATIONAL FUNCTIONING AND PERFORMANCE ON TRENDS (P<0.05) IN THE YOGA GROUP, BUT NOT IN THE OTHER TWO GROUPS. MAXIMUM IMPROVEMENT OCCURRED AT THE END OF 2 MONTHS, AND IMPROVEMENT IN POSITIVE AND NEGATIVE SYMPTOMS PERSISTED AT THE END OF 4 MONTHS. CONCLUSION: YOGA THERAPY CAN BE A USEFUL ADD-ON TREATMENT TO IMPROVE PSYCHOPATHOLOGY, FERD, AND SOCIO-OCCUPATIONAL FUNCTIONING IN ANTIPSYCHOTIC-STABILIZED PATIENTS WITH SCHIZOPHRENIA.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
5 2796  35 YOGA THERAPY FOR OBSESSIVE COMPULSIVE DISORDER (OCD): A CASE SERIES FROM INDIA. YOGA IS AN ANCIENT SCIENCE WHICH HAS BEEN FOUND TO BE HELPFUL IN THE MANAGEMENT OF SEVERAL PSYCHIATRIC DISORDERS INCLUDING OBSESSIVE COMPULSIVE DISORDER (OCD). YOGA AS ADD-ON TREATMENT IN OCD MAY HELP ADDRESS ISSUES LIKE PARTIAL RESPONSE AND ADVERSE EFFECTS OF MEDICATIONS. HOWEVER, RESEARCH IN THIS AREA IS SPARSE, WHICH LED US TO EXPLORE IT THROUGH THIS CASE SERIES. IN THIS CASE SERIES WE HAVE DESCRIBED THE BENEFITS OF 1 MONTH OF YOGA AS ADD-ON TREATMENT IN PATIENTS WITH OCD. ALL PATIENTS WERE ON STABLE DOSES OF MEDICATIONS PRIOR TO AND DURING YOGA PRACTICE. PRE-POST ASSESSMENTS FOR THE CORE SYMPTOMS OF OBSESSION/COMPULSIONS AS WELL AS DEPRESSIVE AND ANXIETY SYMPTOMS WERE DONE. THE ASSESSMENTS SHOWED SIGNIFICANT IMPROVEMENT IN Y-BOCS AND HAM-D SCORES AFTER 1 MONTH OF YOGA. YOGA THERAPY COULD BE AN EFFECTIVE ADD-ON THERAPY FOR THE TREATMENT OF OCD.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
6  272  39 ADD-ON YOGA THERAPY FOR SOCIAL COGNITION IN SCHIZOPHRENIA: A PILOT STUDY. BACKGROUND: YOGA AS A MIND-BODY THERAPY IS USEFUL IN LIFESTYLE-RELATED DISORDERS INCLUDING NEUROPSYCHIATRIC DISORDERS. IN SCHIZOPHRENIA PATIENTS, YOGA HAS BEEN SHOWN TO SIGNIFICANTLY IMPROVE NEGATIVE SYMPTOMS, FUNCTIONING, AND PLASMA OXYTOCIN LEVEL. AIM: THE AIM OF THE STUDY WAS TO STUDY THE EFFECT OF ADD-ON YOGA THERAPY ON SOCIAL COGNITION IN SCHIZOPHRENIA PATIENTS. MATERIALS AND METHODS: IN A SINGLE PRE-POST, STUDY DESIGN, 15 SCHIZOPHRENIA PATIENTS STABILIZED ON ANTIPSYCHOTIC MEDICATION FOR 6 WEEKS WERE ASSESSED FOR SOCIAL COGNITION (THEORY OF MIND, FACIAL EMOTION RECOGNITION, AND SOCIAL PERCEPTION [SP]) AND CLINICAL SYMPTOMS (NEGATIVE AND POSITIVE SYMPTOMS AND SOCIAL DISABILITY) BEFORE AND AFTER TWENTY SESSIONS OF ADD-ON YOGA THERAPY. RESULTS: THERE WAS A SIGNIFICANT IMPROVEMENT IN THE SOCIAL COGNITION COMPOSITE SCORE AFTER 20 SESSIONS OF YOGA (T[13] = -5.37, P </= 0.001). CLINICAL SYMPTOMS ALSO REDUCED SIGNIFICANTLY AFTER TWENTY SESSIONS OF YOGA. CONCLUSION: RESULTS ARE PROMISING TO INTEGRATE YOGA IN CLINICAL PRACTICE, IF PROVEN IN WELL-CONTROLLED CLINICAL TRIALS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
7  746  49 EFFECT OF SAHAJ YOGA ON NEURO-COGNITIVE FUNCTIONS IN PATIENTS SUFFERING FROM MAJOR DEPRESSION. COGNITIVE FUNCTIONS ARE IMPAIRED IN MAJOR DEPRESSION. STUDIES ON THE EFFECTS OF YOGA ON COGNITIVE FUNCTIONS HAVE SHOWN IMPROVEMENT IN MEMORY, VIGILANCE AND ANXIETY LEVELS. 30 PATIENTS SUFFERING FROM MAJOR DEPRESSION (AGE 18 TO 45 YEARS) WERE RANDOMLY DIVIDED INTO TWO GROUPS: GROUP 1: (10 MALES AND 5 FEMALES) PATIENTS WHO PRACTISED SAHAJ YOGA MEDITATION AND ALSO RECEIVED CONVENTIONAL ANTI-DEPRESSANT MEDICATION. GROUP 2: (9 MALES AND 6 FEMALES) PATIENTS WHO ONLY RECEIVED CONVENTIONAL ANTIDEPRESSANT MEDICATION. GROUP 1 PATIENTS WERE ADMINISTERED SAHAJ YOGA PRACTICE FOR 8 WEEKS. NEURO-COGNITIVE TEST BATTERY CONSISTING OF LETTER CANCELLATION TEST (LCT), TRAIL MAKING TEST 'A' (TTA), TRAIL MAKING TEST 'B' (TTB), RUFF FIGURAL FLUENCY TEST (RFFT), FORWARD DIGIT SPAN (FDS) & REVERSE DIGIT SPAN TEST (RDS) WAS USED TO ASSESS FOLLOWING COGNITIVE DOMAINS: ATTENTION SPAN, VISUO-MOTOR SPEED, SHORT-TERM MEMORY, WORKING MEMORY AND EXECUTIVE FUNCTIONS. AFTER 8 WEEKS, BOTH GROUP 1 AND GROUP 2 SUBJECTS SHOWED SIGNIFICANT IMPROVEMENT IN LCT, TTA & TTB BUT IMPROVEMENT IN LCT WAS MORE MARKED IN GROUP 1 SUBJECTS. ALSO, THERE WAS SIGNIFICANT IMPROVEMENT IN RDS SCORES IN ONLY GROUP 1 SUBJECTS (P < 0.05). THE RESULTS THEREBY, DEMONSTRATE THAT SAHAJ YOGA PRACTICE IN ADDITION TO THE IMPROVEMENT IN VARIOUS OTHER COGNITIVE DOMAINS SEEN WITH CONVENTIONAL ANTI-DEPRESSANTS, CAN LEAD TO ADDITIONAL IMPROVEMENT IN EXECUTIVE FUNCTIONS LIKE MANIPULATION OF INFORMATION IN THE VERBAL WORKING MEMORY AND ADDED IMPROVEMENT IN ATTENTION SPAN AND VISUO-MOTOR SPEED OF THE DEPRESSIVES.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
8 2782  40 YOGA THERAPY AS AN ADD-ON TREATMENT IN THE MANAGEMENT OF PATIENTS WITH SCHIZOPHRENIA--A RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: TREATMENT OF SCHIZOPHRENIA HAS REMAINED UNSATISFACTORY DESPITE THE AVAILABILITY OF ANTIPSYCHOTICS. THIS STUDY EXAMINED THE EFFICACY OF YOGA THERAPY (YT) AS AN ADD-ON TREATMENT TO THE ONGOING ANTIPSYCHOTIC TREATMENT. METHOD: SIXTY-ONE MODERATELY ILL SCHIZOPHRENIA PATIENTS WERE RANDOMLY ASSIGNED TO YT (N = 31) AND PHYSICAL EXERCISE THERAPY (PT; N = 30) FOR 4 MONTHS. THEY WERE ASSESSED AT BASELINE AND 4 MONTHS AFTER THE START OF INTERVENTION, BY A RATER WHO WAS BLIND TO THEIR GROUP STATUS. RESULTS: FORTY-ONE SUBJECTS (YT = 21; PT = 20) WERE AVAILABLE AT THE END OF 4 MONTHS FOR ASSESSMENT. SUBJECTS IN THE YT GROUP HAD SIGNIFICANTLY LESS PSYCHOPATHOLOGY THAN THOSE IN THE PT GROUP AT THE END OF 4 MONTHS. THEY ALSO HAD SIGNIFICANTLY GREATER SOCIAL AND OCCUPATIONAL FUNCTIONING AND QUALITY OF LIFE. CONCLUSION: BOTH NON-PHARMACOLOGICAL INTERVENTIONS CONTRIBUTE TO REDUCTION IN SYMPTOMS, WITH YT HAVING BETTER EFFICACY.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
9  745  49 EFFECT OF SAHAJ YOGA ON DEPRESSIVE DISORDERS. SAHAJ YOGA IS A MEDITATIVE TECHNIQUE THAT HAS BEEN FOUND TO HAVE BENEFICIAL EFFECTS IN SOME PSYCHO-SOMATIC ILLNESSES. THE STUDY WAS CARRIED OUT ON 30 CASES (19 MALES, 11 FEMALES, AGE 18-45 YEARS) OF MAJOR DEPRESSION DIAGNOSED ON THE BASIS OF DSM IV CRITERIA. THE PATIENTS WERE THEN RANDOMLY DIVIDED INTO TWO GROUPS: GROUP 1: (10 MALES & 5 FEMALES) PATIENTS WHO WERE PRACTISING SAHAJ YOGA AND ALSO RECEIVED CONVENTIONAL ANTI-DEPRESSANTS. GROUP 2: (9 MALES & 6 FEMALES) PATIENTS WHO WERE ONLY RECEIVING CONVENTIONAL ANTI-DEPRESSANTS. TRAINING IN SAHAJ YOGA WAS CONDUCTED UNDER THE SUPERVISION OF A TRAINED SAHAJ YOGI FOR 8 WEEKS. AT START OF THE STUDY, ALL THE PATIENTS WERE SUBJECTED TO HAMILTON RATING SCALE FOR DEPRESSION (HAM-D) AND HAMILTON RATING SCALE FOR ANXIETY (HAM-A). ABOVE SCALES WERE AGAIN ASSESSED AFTER TWO MONTHS OF TREATMENT. THERE WAS SIGNIFICANT IMPROVEMENT IN HAM-D AS WELL AS HAM-A SCORES IN BOTH GROUP 1 AND GROUP 2 PATIENTS (P<0.001). HOWEVER, PERCENTAGE IMPROVEMENT IN HAM-D SCORES AND HAM-A SCORES IN PATIENTS RECEIVING SAHAJ YOGA WAS SIGNIFICANTLY HIGHER THAN IN GROUP 2 PATIENTS. THE NUMBER OF PATIENTS WHO WENT INTO REMISSION AFTER TWO MONTHS OF INTERVENTION WERE ALSO SIGNIFICANTLY HIGHER IN GROUP 1 PATIENTS (P=0.02). THE PRESENT STUDY DEMONSTRATES THAT SAHAJ YOGA HAS GOT A POTENTIAL ROLE AS A COMPONENT IN THE MANAGEMENT OF DEPRESSIVE DISORDERS.	2005	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
10  288  39 ADJUNCTIVE COGNITIVE REMEDIATION FOR SCHIZOPHRENIA USING YOGA: AN OPEN, NON-RANDOMIZED TRIAL. BACKGROUND: YOGA THERAPY (YT) IMPROVES COGNITIVE FUNCTION IN HEALTHY INDIVIDUALS, BUT ITS IMPACT ON COGNITIVE FUNCTION AMONG PERSONS WITH SCHIZOPHRENIA (SZ) HAS NOT BEEN INVESTIGATED. AIMS: EVALUATE ADJUNCTIVE YT FOR COGNITIVE DOMAINS IMPAIRED IN SZ. METHODS: PATIENTS WITH SZ RECEIVED YT OR TREATMENT AS USUAL (TAU; N = 65, N = 23, RESPECTIVELY). ACCURACY AND SPEED FOR SEVEN COGNITIVE DOMAINS WERE ASSESSED USING A COMPUTERIZED NEUROCOGNITIVE BATTERY (CNB), THUS MINIMIZING OBSERVER BIAS. SEPARATELY, YT WAS EVALUATED AMONG PATIENTS WITH BIPOLAR I DISORDER (N = 40), MAJOR DEPRESSIVE DISORDER (N = 37), AND CARDIOLOGY OUTPATIENTS (N = 68). ALL PATIENTS ALSO RECEIVED ROUTINE PHARMACOTHERAPY. PATIENTS WERE NOT RANDOMIZED TO YT OR TAU. RESULTS: COMPARED WITH THE SZ/TAU GROUP, THE SZ/YT GROUP SHOWED SIGNIFICANTLY GREATER IMPROVEMENT WITH REGARD TO MEASURES OF ATTENTION FOLLOWING CORRECTIONS FOR MULTIPLE COMPARISONS; THE CHANGES WERE MORE PROMINENT AMONG THE MEN. IN THE OTHER DIAGNOSTIC GROUPS, DIFFERING PATTERNS OF IMPROVEMENTS WERE NOTED WITH SMALL TO MEDIUM EFFECT SIZES. CONCLUSIONS: OUR INITIAL ANALYSES SUGGEST NOMINALLY SIGNIFICANT IMPROVEMENT IN COGNITIVE FUNCTION IN SCHIZOPHRENIA WITH ADJUNCTIVE THERAPIES SUCH AS YT. THE MAGNITUDE OF THE CHANGE VARIES BY COGNITIVE DOMAIN AND MAY ALSO VARY BY DIAGNOSTIC GROUP.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
11  915  48 EFFECTIVENESS OF RAJYOGA MEDITATION AS AN ADJUNCT TO FIRST-LINE TREATMENT IN PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER. BACKGROUND: YOGA IS A SET OF MENTAL, PHYSICAL, AND SPIRITUAL PRACTICES WITH ITS ORIGIN IN ANCIENT INDIA. THE RENEWED INTEREST IN YOGA HAS LED TO THE EXPLORATION OF ITS BENEFITS IN A VARIETY OF PSYCHIATRIC DISORDERS SUCH AS SCHIZOPHRENIA, DEPRESSION, AND ANXIETY DISORDERS. THERE IS A DEARTH OF LITERATURE ON THE EFFECT OF YOGA IN OBSESSIVE COMPULSIVE DISORDER (OCD) IN THE INDIAN CONTEXT. AIM: THE PRESENT STUDY WAS CONDUCTED TO FIND OUT THE EFFICACY OF RAJYOGA MEDITATION (RM) AS AN ADJUNCT TO THE FIRST-LINE TREATMENT IN THE TREATMENT OF OCD. MATERIALS AND METHODS: PATIENTS WITH OCD (DIAGNOSED ACCORDING TO DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS FIFTH EDITION) WERE DIVIDED INTO TWO GROUPS - (I) THE MEDITATION GROUP (MG), WHICH INCLUDED 28 PATIENTS AND (II) THE NONMEDITATIVE GROUP (NMG), WHICH INCLUDED 22 PATIENTS. MG PRACTICED RM PROTOCOL FOR 3 MONTHS DURATION IN ADDITION TO THE PHARMACOLOGICAL TREATMENT. THE NMG CONTINUED ON PHARMACOLOGICAL MANAGEMENT AS USUAL. THE SYMPTOMATOLOGY WAS ASSESSED AT BASELINE AND 3 MONTHS USING THE YALE-BROWN OBSESSIVE-COMPULSIVE SCALE (Y-BOCS). RESULTS: AT 3 MONTHS, BOTH GROUPS DEMONSTRATED IMPROVEMENT IN SYMPTOMS. THE IMPROVEMENT IN MG WAS STATISTICALLY SIGNIFICANT WITH A CHANGE OF 9.0 +/- 3.16 IN Y-BOCS AND A 49.76 +/- 9.52% REDUCTION IN SYMPTOMS. IMPROVEMENT SCORES OF NMG WERE ALSO STATISTICALLY SIGNIFICANT WITH A CHANGE OF 3.13 +/- 2.59 IN Y-BOCS AND 18.09 +/- 14.69% REDUCTION IN SYMPTOMS. MG SHOWED SIGNIFICANTLY MORE IMPROVEMENT IN Y-BOCS SCORES (49.76 +/- 9.52) AS COMPARED TO NMG (18.09 +/- 14.69) USING THE STUDENT'S PAIRED T-TEST (P < 0.001). CONCLUSION: THE PRESENT STUDY SUGGESTS THAT THE RM IS AN EFFECTIVE ADJUNCTIVE THERAPY TO REDUCE OBSESSIONS AND COMPULSIONS IN PATIENTS WITH OCD.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
12 1129  47 EFFICACY OF YOGA AS AN ADD-ON TREATMENT FOR IN-PATIENTS WITH FUNCTIONAL PSYCHOTIC DISORDER. CONTEXT: THE EFFICACY OF YOGA AS AN INTERVENTION FOR IN-PATIENTS WITH PSYCHOSIS IS AS YET UNKNOWN; ALTHOUGH, PREVIOUS STUDIES HAVE SHOWN EFFICACY IN STABILIZED OUT-PATIENTS WITH SCHIZOPHRENIA. AIM: THIS STUDY AIMED TO COMPARE THE EFFECT OF ADD-ON YOGA THERAPY OR PHYSICAL EXERCISE ALONG WITH STANDARD PHARMACOTHERAPY IN THE TREATMENT OF IN-PATIENTS WITH PSYCHOSIS. SETTINGS AND DESIGN: THIS STUDY WAS PERFORMED IN AN IN-PATIENT SETTING USING A RANDOMIZED CONTROLLED SINGLE BLIND DESIGN. MATERIALS AND METHODS: A TOTAL OF 88 CONSENTING IN-PATIENTS WITH PSYCHOSIS WERE RANDOMIZED INTO YOGA THERAPY GROUP (N=44) AND PHYSICAL EXERCISE GROUP (N=44). SIXTY PATIENTS COMPLETED THE STUDY PERIOD OF 1(1/2) MONTHS. PATIENTS WHO COMPLETED IN THE YOGA GROUP (N=35) AND IN THE EXERCISE GROUP (N=25) WERE SIMILAR ON THE DEMOGRAPHIC PROFILE, ILLNESS PARAMETERS AND PSYCHOPATHOLOGY SCORES AT BASELINE. RESULTS: THE TWO TREATMENT GROUPS WERE NOT DIFFERENT ON THE CLINICAL SYNDROME SCORES AT THE END OF 2 WEEKS. AT THE END OF 6 WEEKS, PATIENTS IN THE YOGA GROUP HOWEVER HAD LOWER MEAN SCORES ON CLINICAL GLOBAL IMPRESSION SEVERITY (CGIS), POSITIVE AND NEGATIVE SYNDROME SCALE (TOTAL AND GENERAL PSYCHOPATHOLOGY SUBSCALE) AND HAMILTON DEPRESSION RATING SCALE (HDRS) (P<0.05). REPEATED MEASURE ANALYSIS OF VARIANCE DETECTED AN ADVANTAGE FOR YOGA OVER EXERCISE IN REDUCING THE CLINICAL CGIS AND HDRS SCORES. CONCLUSION: ADDING YOGA INTERVENTION TO STANDARD PHARMACOLOGICAL TREATMENT IS FEASIBLE AND MAY BE BENEFICIAL EVEN IN THE EARLY AND ACUTE STAGE OF PSYCHOSIS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
13 2799  44 YOGA THERAPY FOR SOCIAL COGNITION IN SCHIZOPHRENIA: AN EXPERIMENTAL MEDICINE-BASED RANDOMIZED CONTROLLED TRIAL. NEGATIVE SYMPTOMS AND COGNITIVE DEFICITS ARE DIFFICULT-TO-TREAT SYMPTOMS OF SCHIZOPHRENIA. IN THIS SINGLE BLIND RANDOMIZED CONTROLLED STUDY, WE COMPARED CHANGE IN SOCIAL COGNITIVE PERFORMANCE IN PERSONS WITH SCHIZOPHRENIA (PWS) (AS PER DSM-5), AFTER 6 WEEKS OF YOGA INTERVENTION WITH A WAITLIST CONTROL GROUP. WE ALSO EXAMINED CHANGES IN PUTATIVE MIRROR NEURON SYSTEM (MNS) ACTIVITY MEASURED BY TRANSCRANIAL MAGNETIC STIMULATION (TMS) IN A SUBSET OF SAMPLE (N = 30). 51 PWS STABILIZED ON ANTIPSYCHOTIC MEDICATION FOR AT LEAST 6 WEEKS, WERE ASSIGNED TO ADD-ON YOGA THERAPY (YT) (N = 26) OR WAITLIST (WL) (N = 25). SUBJECTS IN THE YT GROUP RECEIVED ADD-ON YOGA THERAPY (20 SESSIONS IN 6 WEEKS). BOTH THE GROUPS CONTINUED THEIR STANDARD TREATMENT AND WERE ASSESSED AT BASELINE AND AFTER 6 WEEKS FOR SOCIAL COGNITION, CLINICAL SYMPTOMS AND SOCIAL DISABILITY. RM-ANOVA SHOWED SIGNIFICANT INTERACTION BETWEEN TIME AND GROUP FOR SOCIAL COGNITION COMPOSITE SCORE (SCCS) (F = 42.09 [1,44], P < 0.001); NEGATIVE SYMPTOMS (SANS) (F = 74.91 [1,45], P < 0.001); POSITIVE SYMPTOMS (SAPS) (F = 16.05 [1,45], P < 0.001) AND SOCIAL DISABILITY (GSDS) (F = 29.91 [1,46], P < 0.001). MNS ACTIVITY HAD INCREASED AFTER 6 WEEKS IN BOTH GROUPS BUT NOT OF STATISTICAL SIGNIFICANCE. THIS STUDY DEMONSTRATES THAT 6 WEEKS OF ADD-ON YOGA THERAPY COULD IMPROVE SOCIAL COGNITION IN PWS COMPARED TO WAITLIST CONTROL SUBJECTS. HOWEVER, THE CHANGE IN SOCIAL COGNITION WAS NOT ASSOCIATED WITH A CHANGE IN THE PUTATIVE MNS-ACTIVITY. IT NECESSIATATES FURTHER STUDIES TO INVESTIGATE THE MECHANISTIC PROCESSES OF YOGA AND REPLICATE THESE OBSERVATIONS IN A LARGER SAMPLE.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
14 1423  43 IMPROVEMENT IN NEUROCOGNITIVE FUNCTIONS AND SERUM BRAIN-DERIVED NEUROTROPHIC FACTOR LEVELS IN PATIENTS WITH DEPRESSION TREATED WITH ANTIDEPRESSANTS AND YOGA. CONTEXT AND AIMS: IMPAIRMENT IN COGNITION IS WELL-KNOWN IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER. THIS STUDY EXAMINED THE EFFECT OF YOGA THERAPY WITH OR WITHOUT ANTIDEPRESSANTS AND ANTIDEPRESSANTS ALONE ON CERTAIN NEUROPSYCHOLOGICAL FUNCTIONS IN PATIENTS WITH DEPRESSION. CORRELATION BETWEEN CHANGES IN NEUROPSYCHOLOGICAL TEST PERFORMANCE AND SERUM BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) LEVELS WAS ALSO EXPLORED. MATERIALS AND METHODS: ANTIDEPRESSANT-NAIVE/ANTIDEPRESSANT-FREE OUTPATIENTS WITH DEPRESSION RECEIVED ANTIDEPRESSANT MEDICATION ALONE (N = 23) OR YOGA THERAPY WITH (N = 26) OR WITHOUT (N = 16) ANTIDEPRESSANTS. DEPRESSION WAS ASSESSED USING THE HAMILTON DEPRESSION RATING SCALE. NEUROPSYCHOLOGICAL TESTS INCLUDED DIGIT-SPAN FORWARD AND BACKWARD, REY AUDITORY VERBAL LEARNING TEST, AND TRAIL MAKING TESTS (TMT-A AND B). THESE TESTS WERE ADMINISTERED BEFORE AND 3 MONTHS AFTER THE TREATMENT IN PATIENTS, AND ONCE IN HEALTHY COMPARISON SUBJECTS (N = 19). STATISTICAL ANALYSIS: BASELINE DIFFERENCES WERE ANALYZED USING INDEPENDENT SAMPLE T-TEST, CHI-SQUARE, AND ONE-WAY ANOVA. PAIRED T-TEST WAS USED TO ANALYZE THE CHANGE FROM BASELINE TO FOLLOW-UP. PEARSON'S CORRELATION WAS USED TO EXPLORE THE ASSOCIATION OF CHANGE BETWEEN 2 VARIABLES. RESULTS: PATIENTS HAD IMPAIRED PERFORMANCE ON MOST NEUROPSYCHOLOGICAL TESTS. AFTER 3 MONTHS, THERE WAS SIGNIFICANT IMPROVEMENT - PATIENTS' PERFORMANCE WAS COMPARABLE TO THAT OF HEALTHY CONTROLS ON MAJORITY OF THE TESTS. SIGNIFICANT INVERSE CORRELATION WAS OBSERVED BETWEEN INCREASE IN BDNF LEVELS AND IMPROVEMENT IN TMT "A" DURATION IN YOGA-ALONE GROUP (R = -0.647; P = 0.009). CONCLUSIONS: TO CONCLUDE THAT, YOGA THERAPY, ALONE OR IN COMBINATION WITH MEDICATIONS, IS ASSOCIATED WITH IMPROVED NEUROPSYCHOLOGICAL FUNCTIONS AND NEUROPLASTIC EFFECTS IN PATIENTS WITH DEPRESSION.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                      
15 1252  48 FEASIBILITY, ACCEPTABILITY AND EVALUATION OF MEDITATION TO AUGMENT YOGA PRACTICE AMONG PERSONS DIAGNOSED WITH SCHIZOPHRENIA. OBJECTIVE: TO DESIGN A MEDITATION PROTOCOL AND TEST ITS FEASIBILITY, ACCEPTABILITY AND EFFICACY IN CONJUNCTION WITH YT FOR PERSONS WITH SCHIZOPHRENIA (SZ). METHODS: THE MEDITATION PROTOCOL CONSISTED OF ANAPANA (OBSERVING NORMAL RESPIRATION) AND YOGA NIDRA (SUPINE, RESTFUL AWARENESS). IN A SINGLE BLIND RANDOMIZED CONTROLLED TRIAL, MEDICATED AND CLINICALLY STABLE OUTPATIENTS DIAGNOSED WITH SZ WERE RANDOMIZED TO RECEIVE TREATMENT AS USUAL (TAU), TAU AUGMENTED WITH YOGA TRAINING (YT), OR TAU AUGMENTED WITH MEDITATION AND YOGA TRAINING (MYT) FOR THREE WEEKS (N=145). ACCEPTABILITY, CLINICAL, SOCIAL AND COGNITIVE FUNCTIONS WERE ASSESSED AFTER 3 WEEKS AND 3 MONTHS POST RANDOMIZATION USING WITHIN GROUP AND BETWEEN GROUPS ANALYSES WITH REPEATED MEASURES MULTIVARIATE TESTS. RESULTS: NO GROUP-WISE DIFFERENCES IN COMPLIANCE, STUDY DISCONTINUATION, MAJOR/SERIOUS SIDE EFFECTS OR ADVERSE EVENTS WERE NOTED. FOR SIX ASSESSED CLINICAL VARIABLES, THE DIRECTION OF CHANGES WERE IN THE DESIRED DIRECTION AND THE EFFECT SIZES WERE GREATER IN THE MYT GROUP COMPARED WITH THE TAU GROUP AT BOTH TIME POINTS. CHANGES IN SOCIAL FUNCTION VARIABLES WERE GREATER AT 3 MONTHS THAN AT 3 WEEKS. NOMINALLY SIGNIFICANT IMPROVEMENT IN INDIVIDUAL COGNITIVE DOMAINS WERE NOTED IN ALL GROUPS AT BOTH TIME POINTS. ALL EFFECT SIZES WERE IN THE SMALL TO MEDIUM RANGE. CONCLUSION: MYT IS FEASIBLE, ACCEPTABLE AND SHOWS MODEST BENEFITS FOR PERSONS WITH SZ. MYT CAN ALSO IMPROVE QUALITY OF LIFE AND CLINICAL SYMPTOMS. LARGER STUDIES OF LONGER DURATION ARE WARRANTED.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
16 2293  51 THERAPEUTIC EFFICACY OF ADD-ON YOGASANA INTERVENTION IN STABILIZED OUTPATIENT SCHIZOPHRENIA: RANDOMIZED CONTROLLED COMPARISON WITH EXERCISE AND WAITLIST. BACKGROUND: SCHIZOPHRENIA IS A HIGHLY DISABLING ILLNESS. PREVIOUS STUDIES HAVE SHOWN YOGA TO BE A FEASIBLE ADD-ON THERAPY IN SCHIZOPHRENIA. AIMS: THE CURRENT STUDY AIMED TO TEST THE EFFICACY OF YOGA AS AN ADD-ON TREATMENT IN OUTPATIENTS WITH SCHIZOPHRENIA. SETTINGS AND DESIGN: THE STUDY DONE AT A TERTIARY PSYCHIATRY CENTER USED A SINGLE BLIND RANDOMIZED CONTROLLED DESIGN WITH ACTIVE CONTROL AND WAITLIST GROUPS. MATERIALS AND METHODS: CONSENTING PATIENTS WITH SCHIZOPHRENIA WERE RANDOMIZED INTO YOGA, EXERCISE, OR WAITLIST GROUP. THEY CONTINUED TO RECEIVE PHARMACOLOGICAL THERAPY THAT WAS UNCHANGED DURING THE STUDY. PATIENTS IN THE YOGA OR EXERCISE GROUP WERE OFFERED SUPERVISED DAILY PROCEDURES FOR ONE MONTH. ALL PATIENTS WERE ASSESSED BY A BLIND RATER AT THE START OF THE INTERVENTION AND AT THE END OF 4 MONTHS. RESULTS: KENDALL TAU, A NONPARAMETRIC STATISTICAL TEST, SHOWED THAT SIGNIFICANTLY MORE PATIENTS IN THE YOGA GROUP IMPROVED IN POSITIVE AND NEGATIVE SYNDROME SCALE (PANSS) NEGATIVE AND TOTAL PANSS SCORES AS WELL AS SOCIAL FUNCTIONING SCORES COMPARED WITH THE EXERCISE AND WAITLIST GROUP. ODDS RATIO ANALYSIS SHOWED THAT THE LIKELIHOOD OF IMPROVEMENT IN YOGA GROUP IN TERMS OF NEGATIVE SYMPTOMS WAS ABOUT FIVE TIMES GREATER THAN EITHER THE EXERCISE OR WAITLIST GROUPS. CONCLUSION: IN SCHIZOPHRENIA PATIENTS WITH SEVERAL YEARS OF ILLNESS AND ON STABILIZED PHARMACOLOGICAL THERAPY, ONE-MONTH TRAINING FOLLOWED BY THREE MONTHS OF HOME PRACTICES OF YOGA AS AN ADD-ON TREATMENT OFFERED SIGNIFICANT ADVANTAGE OVER EXERCISE OR TREATMENT AS USUAL. YOGA HOLDS PROMISE AS A COMPLEMENTARY INTERVENTION IN THE MANAGEMENT OF SCHIZOPHRENIA.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
17 1356  53 IMMEDIATE EFFECT OF TWO YOGA-BASED RELAXATION TECHNIQUES ON COGNITIVE FUNCTIONS IN PATIENTS SUFFERING FROM RELAPSING REMITTING MULTIPLE SCLEROSIS: A COMPARATIVE STUDY. COGNITIVE IMPAIRMENT (CI) IS AN IMPORTANT FEATURE OF RELAPSING REMITTING MULTIPLE SCLEROSIS (RRMS). YOGIC RELAXATION TECHNIQUES HAVE BEEN FOUND USEFUL IN IMPROVING VARIOUS COGNITIVE DOMAINS IN HEALTH AND DISEASE. EIGHTEEN SUBJECTS (13 FEMALES) IN THE AGE RANGE OF 51.5 +/- 12.72 YEARS WITH THE DIAGNOSIS OF RRMS BY A NEUROLOGIST (MCDONALD CRITERIA 2010) SINCE LAST 18.16 +/- 12.59 YEARS WERE RECRUITED INTO THE STUDY FROM A NEURO-REHABILITATION CENTRE IN GERMANY. ASSESSMENTS WERE DONE BEFORE AND IMMEDIATELY AFTER TWO RANDOMLY ALLOCATED 30-MIN SESSIONS OF YOGIC RELAXATION: CYCLIC MEDITATION (CM) AND SR (SUPINE REST OR SHAVASANA). ASSESSMENTS WERE DONE FOR ATTENTION, PSYCHOMOTOR PERFORMANCE, INFORMATION PROCESSING SPEED, EXECUTIVE FUNCTIONS, AND IMMEDIATE AND DELAYED RECALL USING STANDARD PSYCHOMETRIC TOOLS. RMANOVA WAS APPLIED TO ANALYSE THE DATA USING SPSS VERSION 10. BOTH CM AND SR SESSIONS IMPROVED SCORES ON DIGIT SYMBOL SUBSTITUTION TEST (DSST) (P < 0.01) AND AUDITORY VERBAL LEARNING TEST (AVLT) (P < 0.05). THERE WAS A SIGNIFICANTLY BETTER PERFORMANCE IN TRAIL MAKING TEST (TMT)-A AND FORWARD DIGIT SPAN (FDS) AFTER CM AS COMPARED TO SR (P < 0.01). YOGIC RELAXATION TECHNIQUES MAY HAVE AN IMMEDIATE ENHANCING EFFECT ON PROCESSING SPEED, PSYCHOMOTOR PERFORMANCE, AND RECALL OF RRMS PATIENTS. CM IS BETTER THAN SR IN IMPROVING PROCESSING SPEED, SHORT-TERM MEMORY, AND VERBAL WORKING MEMORY.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
18 1227  52 FEASIBILITY AND EFFICACY OF YOGA AS AN ADD-ON INTERVENTION IN ATTENTION DEFICIT-HYPERACTIVITY DISORDER: AN EXPLORATORY STUDY. CONTEXT: ATTENTION DEFICIT-HYPERACTIVITY DISORDER (ADHD) IS ONE OF THE MOST COMMON NEURODEVELOPMENTAL DISORDERS. STIMULANT MEDICATION IS FREQUENTLY USED IN MANAGEMENT, WITH SIGNIFICANT ADVERSE EFFECTS. THERE IS A GROWING INTEREST IN COMPLEMENTARY TREATMENTS LIKE YOGA. AIMS: TO STUDY THE EFFECTS OF YOGA AS A COMPLEMENTARY THERAPY IN CHILDREN WITH MODERATE TO SEVERE ADHD. SETTINGS AND DESIGN: THE STUDY WAS PERFORMED ON CHILDREN (CONSENT WAS TAKEN FROM PARENTS) ADMITTED IN A CHILD PSYCHIATRY UNIT USING AN OPEN-LABEL EXPLORATORY STUDY. MATERIALS AND METHODS: CHILDREN BETWEEN 5 AND 16 YEARS OF AGE DIAGNOSED WITH ADHD AND CO-OPERATIVE FOR YOGA WERE INCLUDED. SUBJECTS WITH OTHER SERIOUS PSYCHIATRIC AND MEDICAL ILLNESSES WERE EXCLUDED. THE PARTICIPANTS WERE GIVEN YOGA TRAINING DAILY DURING THEIR IN-PATIENT STAY. THEY WERE RATED ON CONNERS' ABBREVIATED RATING SCALE - (CARS), ADHD-RATING SCALE-IV (ADHD - RS IV) AND CLINICAL GLOBAL IMPRESSION (CGI)-SEVERITY, AT THE BEGINNING OF STUDY, AT DISCHARGE AND SUBSEQUENTLY AT THE END OF 1(ST), 2(ND) AND 3(RD) MONTH BY A RESEARCH ASSOCIATE NOT INVOLVED IN YOGA INSTRUCTION. PAIRED T-TEST WAS EMPLOYED TO COMPARE THE MEANS OF SCORES BETWEEN BASELINE AND FOLLOW-UPS. RESULTS: A TOTAL OF 9 CHILDREN (8 MALES, 1 FEMALE) WERE RECRUITED INTO THE STUDY. ALL, BUT ONE WERE ON MEDICATIONS. AN AVERAGE OF 8 YOGA TRAINING SESSIONS WAS GIVEN TO SUBJECTS. THEY WERE ABLE TO LEARN YOGA REASONABLY WELL. THERE WAS A SIGNIFICANT IMPROVEMENT IN THE ADHD SYMPTOMS AS ASSESSED ON CARS (P-0.014), ADHD-RS IV (P=0.021) AND CGI- S SCALES (P=0.004) AT THE TIME OF DISCHARGE.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
19   91  58 A MULTICOMPONENT YOGA-BASED, BREATH INTERVENTION PROGRAM AS AN ADJUNCTIVE TREATMENT IN PATIENTS SUFFERING FROM GENERALIZED ANXIETY DISORDER WITH OR WITHOUT COMORBIDITIES. OBJECTIVES: THE AIM OF THIS STUDY IS TO EVALUATE THE EFFICACY AND TOLERABILITY OF SUDARSHAN KRIYA YOGA (SKY) COURSE IN GENERALIZED ANXIETY DISORDER (GAD) OUTPATIENTS, WHO AFTER EIGHT WEEKS OF AN APPROPRIATE DOSE OF TRADITIONAL THERAPY HAD NOT YET ACHIEVED REMISSION. SUBJECTS: THE ADULT PARTICIPANTS (18-65 YEARS) WERE OUTPATIENTS WITH A PRIMARY DIAGNOSIS OF GAD WITH OR WITHOUT COMORBIDITIES ON THE MINI-INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW (MINI). PARTICIPANTS HAD A MINIMUM OF EIGHT WEEKS STANDARD TREATMENT WITH AN APPROPRIATE DOSE OF A STANDARD PRESCRIPTION ANXIOLYTIC, A CLINICIAN GLOBAL IMPRESSION-SEVERITY (CGI-S) SCORE OF 5-7, A HAMILTON ANXIETY SCALE (HAM-A) TOTAL SCORE >/=20 INCLUDING A SCORE OF >2 ON THE ANXIOUS MOOD AND TENSION ITEMS. MATERIALS AND METHODS: FORTY-ONE PATIENTS WERE ENROLLED IN AN OPEN-LABEL TRIAL OF THE SKY COURSE AS AN ADJUNCT TO STANDARD TREATMENT OF GAD AT THE START CLINIC FOR MOOD AND ANXIETY DISORDERS, A TERTIARY CARE MOOD AND ANXIETY DISORDER CLINIC IN TORONTO. THE SKY COURSE WAS ADMINISTERED OVER FIVE DAYS (22 H TOTAL). SUBJECTS WERE ENCOURAGED TO PRACTICE THE YOGA BREATHING TECHNIQUES AT HOME FOR 20 MIN PER DAY AFTER THE COURSE AND WERE OFFERED GROUP PRACTICE SESSIONS FOR 2 H ONCE A WEEK LED BY CERTIFIED YOGA INSTRUCTORS. THE PRIMARY OUTCOME MEASURE WAS THE MEAN CHANGE FROM PRE-TREATMENT ON THE HAM-A SCALE. PSYCHOLOGICAL MEASURES WERE OBTAINED AT BASELINE AND FOUR WEEKS AFTER COMPLETING THE INTERVENTION. RESULTS: THIRTY-ONE PATIENTS COMPLETED THE PROGRAM (MEAN AGE 42.6 +/- 13.3 YEARS). AMONG COMPLETERS, SIGNIFICANT REDUCTIONS OCCURRED IN THE PRE- AND POST-INTERVENTION MEAN HAM-A TOTAL SCORE (T=4.59; P<0.01) AND PSYCHIC SUBSCALE (T=5.00; P</=0.01). THE RESPONSE RATE WAS 73% AND THE REMISSION RATE 41% AS MEASURED ON THE HAM-A. CONCLUSION: THE RESULTS OF THIS SMALL PILOT TRIAL SUGGEST THAT THE SKY COURSE REPRESENTS A POTENTIALLY VALUABLE ADJUNCT TO STANDARD PHARMACOTHERAPY IN PATIENTS WITH GAD OR TREATMENT-RESISTANT GAD, AND WARRANTS FURTHER INVESTIGATION. IN PARTICULAR, CHANGES IN WORRY AND BODY SYMPTOMS SHOWED SIGNIFICANT IMPROVEMENTS THAT MAY FURTHER OUR UNDERSTANDING OF THE MECHANISM OF CHANGE IN THE TOLERANCE OF ANXIETY AND WORRY.	2012	

20  580  40 DESIGNING AND VALIDATION OF A YOGA-BASED INTERVENTION FOR OBSESSIVE COMPULSIVE DISORDER. SOME YOGA-BASED PRACTICES HAVE BEEN FOUND TO BE USEFUL FOR PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER (OCD). THE AUTHORS COULD NOT FIND A VALIDATED YOGA THERAPY MODULE AVAILABLE FOR OCD. THIS STUDY ATTEMPTED TO FORMULATE A GENERIC YOGA-BASED INTERVENTION MODULE FOR OCD. A YOGA MODULE WAS DESIGNED BASED ON TRADITIONAL AND CONTEMPORARY YOGA LITERATURE. THE MODULE WAS SENT TO 10 YOGA EXPERTS FOR CONTENT VALIDATION. THE EXPERTS RATED THE USEFULNESS OF THE PRACTICES ON A SCALE OF 1-5 (5 = EXTREMELY USEFUL). THE FINAL VERSION OF THE MODULE WAS PILOT-TESTED ON PATIENTS WITH OCD (N = 17) FOR BOTH FEASIBILITY AND EFFECT ON SYMPTOMS. EIGHTY-EIGHT PER CENT (22 OUT OF 25) OF THE ITEMS IN THE INITIAL MODULE WERE RETAINED, WITH MODIFICATIONS IN THE MODULE AS SUGGESTED BY THE EXPERTS ALONG WITH PATIENTS' INPUTS AND AUTHORS' EXPERIENCE. THE MODULE WAS FOUND TO BE FEASIBLE AND SHOWED AN IMPROVEMENT IN SYMPTOMS OF OCD ON TOTAL YALE-BROWN OBSESSIVE-COMPULSIVE SCALE (YBOCS) SCORE (P = 0.001). A GENERIC YOGA THERAPY MODULE FOR OCD WAS VALIDATED BY EXPERTS IN THE FIELD AND FOUND FEASIBLE TO PRACTICE IN PATIENTS. A DECREASE IN THE SYMPTOM SCORES WAS ALSO FOUND FOLLOWING YOGA PRACTICE OF 2 WEEKS. FURTHER CLINICAL VALIDATION IS WARRANTED TO CONFIRM EFFICACY.	2016