1  369 88 AUTONOMIC FUNCTIONS IN RAJA-YOGA MEDITATORS. STRESS, AN INEVITABLE AND CONSTANT FEATURE THROUGHOUT THE LIFETIME, INDUCES AUTONOMIC DYSFUNCTIONS, FOR WHICH MEDITATION IS CONSIDERED TO BE AN ANTIDOTE. SO THE CASE CONTROL STUDY WAS PLANNED INCLUDING 50 RAJA-YOGA MEDITATORS PRACTICING MEDITATION FOR 5 YEARS AND 50 AGE MATCHED NON-MEDITATORS. AUTONOMIC FUNCTION TESTS WERE PERFORMED AND RESULTS WERE COMPARED USING THE STUDENT-T TEST. MEAN VALUES OF RESTING HR, SBP AND DBP WERE LESS IN MEDITATORS. GALVANIC SKIN RESPONSE IN MEDITATORS WAS SIGNIFICANTLY MORE (P < 0.001). MEAN INCREASE BP RESPONSE TO HAND GRIP TEST AND COLD PRESSOR TEST WAS SIGNIFICANTLY LESS IN MEDITATORS THAN NON-MEDITATORS (P < 0.001). STANDING: LYING RATIO, VALSALVA RATIO, INSPIRATION: EXPIRATION RATIO AND 30:15 RATIOS WERE SIGNIFICANTLY INCREASED IN MEDITATORS THAN NON-MEDITATORS. FROM THE RESULTS, THERE WAS SHIFTING OF THE AUTONOMIC BALANCE TO PARASYMPATHETIC SIDE IN RAJA-YOGA MEDITATORS, WHICH SUGGESTS ITS UTILITY TO COMBAT THE ILL EFFECTS OF STRESS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
2 1545 25 LARGER WHOLE BRAIN GREY MATTER ASSOCIATED WITH LONG-TERM SAHAJA YOGA MEDITATION: A DETAILED AREA BY AREA COMPARISON. OBJECTIVES: OUR PREVIOUS STUDY SHOWED THAT LONG-TERM PRACTITIONERS OF SAHAJA YOGA MEDITATION (SYM) HAD AROUND 7% LARGER GREY MATTER VOLUME (GMV) IN THE WHOLE BRAIN COMPARED WITH HEALTHY CONTROLS; HOWEVER, WHEN TESTING INDIVIDUAL REGIONS, ONLY 5 SMALL BRAIN AREAS WERE STATISTICALLY DIFFERENT BETWEEN GROUPS. UNDER THE HYPOTHESIS THAT THOSE RESULTS WERE STATISTICALLY CONSERVATIVE, WITH THE SAME DATASET, WE INVESTIGATED IN MORE DETAIL THE REGIONAL DIFFERENCES IN GMV ASSOCIATED WITH THE PRACTICE OF SYM, WITH A DIFFERENT STATISTICAL APPROACH. DESIGN: TWENTY-THREE EXPERIENCED PRACTITIONERS OF SYM AND 23 HEALTHY NON-MEDITATORS MATCHED ON AGE, SEX AND EDUCATION LEVEL, WERE SCANNED USING STRUCTURAL MAGNETIC RESONANCE IMAGING (MRI). THEIR GMV WERE EXTRACTED AND COMPARED USING VOXEL-BASED MORPHOMETRY (VBM). USING A NOVEL AD-HOC GENERAL LINEAR MODEL, STATISTICAL COMPARISONS WERE MADE TO OBSERVE IF THE GMV DIFFERENCES BETWEEN MEDITATORS AND CONTROLS WERE STATISTICALLY SIGNIFICANT. RESULTS: IN THE 16 LOBE AREA SUBDIVISIONS, GMV WAS STATISTICALLY SIGNIFICANTLY DIFFERENT IN 4 OUT OF 16 AREAS: IN RIGHT HEMISPHERIC TEMPORAL AND FRONTAL LOBES, LEFT FRONTAL LOBE AND BRAINSTEM. IN THE 116 AAL AREA SUBDIVISIONS, GMV DIFFERENCE WAS STATISTICALLY SIGNIFICANT IN 11 AREAS. THE GMV DIFFERENCES WERE STATISTICALLY MORE SIGNIFICANT IN RIGHT HEMISPHERIC BRAIN AREAS. CONCLUSIONS: THE STUDY SHOWS THAT LONG-TERM PRACTICE OF SYM IS ASSOCIATED WITH LARGER GMV OVERALL, AND WITH SIGNIFICANT DIFFERENCES MAINLY IN TEMPORAL AND FRONTAL AREAS OF THE RIGHT HEMISPHERE AND THE BRAINSTEM. THESE NEUROPLASTIC CHANGES MAY REFLECT EMOTIONAL AND ATTENTIONAL CONTROL MECHANISMS DEVELOPED WITH SYM. ON THE OTHER HAND, OUR STATISTICAL AD-HOC METHOD SHOWS THAT THERE WERE MORE BRAIN AREAS WITH STATISTICAL SIGNIFICANCE COMPARED TO THE TRADITIONAL METHODOLOGY WHICH WE THINK IS SUSCEPTIBLE TO CONSERVATIVE TYPE II ERRORS.	2020	
                                                                                      
3 1925 20 ROLE OF YOGA IN ALIENATING THE MEMORY DECLINE AND FRONTAL LOBE METABOLITE CHANGES IN TYPE 2 DIABETES. RECENT RESEARCH STUDIES HAVE ESTABLISHED THE FACT, THAT GLYCOSYLATION IS CAUSING THE MEMORY DECLINE AND THIS IS FURTHER SUPPORTED BY THE ALTERATION OF BRAIN METABOLITE CONCENTRATIONS IN DIABETES. THE PRESENT STUDY IS HYPOTHESIZED THAT YOGA IS HAVING ALIENATING ABILITY OF MEMORY DECLINE AND ALTERATION OF FRONTAL LOBE METABOLITE CONCENTRATIONS, WHICH ARE THE RESULT OF GLYCOSYLATION IN TYPE 2 DIABETES. FIVE TYPE 2 DIABETIC SUBJECTS OF BOTH THE SEX, AGED BETWEEN 35-55 YEARS, WHO PRACTICED YOGA OVER A PERIOD OF SIX MONTHS IN A YOGA INSTITUTE, WERE RECRUITED AS TEST GROUP. AGE AND SEX MATCHED FIVE TYPE 2 DIABETIC SUBJECTS WERE RECRUITED AS CONTROL GROUP, BOTH THE GROUP SUBJECTS ARE ON ORAL HYPOGLYCAEMIC AGENTS. GLYCOSYLATED HAEMOGLOBIN PERCENTAGE WAS ESTIMATED WITH BIO-RAD INSTRUMENT, FRONTAL LOBE METABOLITES WERE ESTIMATED WITH PROTON MAGNETIC RESONANCE SPECTROSCOPY (H-MRS), MEMORY WAS CALCULATED WITH PGI-MEMORY SCALE (PGIMS) THAT IS A PART OF PGI-BATTERY OF BRAIN DYSFUNCTION (PGI-BBD), WHICH IS A NEUROPSYCHOLOGICAL BATTERY. MEAN GLYCOSYLATED HAEMOGLOBIN PERCENTAGE AND MEMORY DYSFUNCTION RATING IN CONTROL AND TEST GROUP SUBJECTS ARE 6.9+/-0.4 & 7.8+/-1.84 (P=0.03), AND 14+/-1& 6+/-1 (P=0.0001) RESPECTIVELY. RIGHT AND LEFT FRONTAL LOBE N-ACETYL ASPARTATE (NAA) AND MYOIONOSITOL (MI) CONCENTRATIONS WERE MORE OR LESS SIMILAR IN BOTH THE GROUPS. YOGA IS HAVING A SIGNIFICANT ROLE IN ALIENATING THE DECLINE IN MEMORY CAUSED BY GLYCOSYLATION IN TYPE 2 DIABETES BUT NOT ON THE ALTERATION OF FRONTAL LOBE NAA AND MI CONCENTRATIONS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
4 1555 20 LONG-TERM ASHTANGA YOGA PRACTICE DECREASES MEDIAL TEMPORAL AND BRAINSTEM GLUCOSE METABOLISM IN RELATION TO YEARS OF EXPERIENCE. BACKGROUND: YOGA IS INCREASINGLY POPULAR WORLDWIDE WITH SEVERAL PHYSICAL AND MENTAL BENEFITS, BUT THE UNDERLYING NEUROBIOLOGY REMAINS UNCLEAR. WHEREAS MANY STUDIES HAVE FOCUSED ON PURE MEDITATIONAL ASPECTS, THE TRIAD OF YOGA INCLUDES MEDITATION, POSTURES, AND BREATHING. WE CONDUCTED A CROSS-SECTIONAL STUDY COMPARING EXPERIENCED YOGA PRACTITIONERS TO YOGA-NAIVE HEALTHY SUBJECTS USING A MULTIPARAMETRIC 2 X 2 DESIGN WITH SIMULTANEOUS POSITRON EMISSION TOMOGRAPHY/MAGNETIC RESONANCE (PET/MR) IMAGING. METHODS: (18)F-FDG PET, MORPHOMETRIC AND DIFFUSION TENSOR IMAGING, RESTING STATE FMRI, AND MR SPECTROSCOPY WERE ACQUIRED IN 10 EXPERIENCED (4.8 +/- 2.3 YEARS OF REGULAR YOGA EXPERIENCE) YOGA PRACTITIONERS AND 15 MATCHED CONTROLS IN REST AND AFTER A SINGLE PRACTICE (YOGA PRACTICE AND PHYSICAL EXERCISE, RESPECTIVELY). RESULTS: IN REST, DECREASED REGIONAL GLUCOSE METABOLISM IN THE MEDIAL TEMPORAL CORTEX, STRIATUM, AND BRAINSTEM WAS OBSERVED IN YOGA PRACTITIONERS COMPARED TO CONTROLS (P < 0.0001), WITH A SIGNIFICANT INVERSE CORRELATION OF RESTING PARAHIPPOCAMPAL AND BRAINSTEM METABOLISM WITH YEARS OF REGULAR YOGA PRACTICE (RHO < - 0.63, P < 0.05). A SINGLE YOGA PRACTICE RESULTED IN SIGNIFICANT HYPERMETABOLISM IN THE CEREBELLUM (P < 0.0001). NONE OF THE MR MEASURES DIFFERED, BOTH AT REST AND AFTER INTERVENTION. CONCLUSIONS: EXPERIENCED YOGA PRACTITIONERS SHOW REGIONAL LONG-TERM DECREASES IN GLUCOSE METABOLISM RELATED TO YEARS OF PRACTICE. TO ELUCIDATE A POTENTIAL CAUSALITY, A PROSPECTIVE LONGITUDINAL STUDY IN YOGA-NAIVE INDIVIDUALS IS WARRANTED.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                          
5 2400 24 YOGA AND DISC DEGENERATIVE DISEASE IN CERVICAL AND LUMBAR SPINE: AN MR IMAGING-BASED CASE CONTROL STUDY. THE OBJECTIVE OF THE CURRENT STUDY WAS TO FIND OUT WHETHER YOGA PRACTICE WAS BENEFICIAL TO THE SPINE BY COMPARING DEGENERATIVE DISC DISEASE IN THE SPINES OF LONG-TIME YOGA PRACTITIONERS AND NON-YOGA PRACTICING CONTROLS, USING AN OBJECTIVE MEASUREMENT TOOL, MAGNETIC RESONANCE IMAGING. THIS MATCHED CASE-CONTROL STUDY COMPRISED 18 YOGA INSTRUCTORS WITH TEACHING EXPERIENCE OF MORE THAN 10 YEARS AND 18 NON-YOGA PRACTICING ASYMPTOMATIC INDIVIDUALS RANDOMLY SELECTED FROM A HEALTH CHECKUP DATABASE. A VALIDATED GRADING SCALE WAS USED TO GRADE THE CONDITION OF CERVICAL AND LUMBAR DISCS SEEN IN MAGNETIC RESONANCE IMAGING OF THE SPINE, AND THE RESULTING DATA ANALYZED STATISTICALLY. THE MEAN NUMBER OF YEARS OF YOGA PRACTICE FOR THE YOGA GROUP WAS 12.9 +/- 7.5. THE OVERALL (CERVICAL + LUMBAR) DISC SCORES OF THE YOGA GROUP WERE SIGNIFICANTLY LOWER (INDICATING LESS DEGENERATIVE DISC DISEASE) THAN THOSE OF THE CONTROL GROUP (P < 0.001). THE SCORES FOR THE CERVICAL VERTEBRAL DISCS OF THE YOGA GROUP WERE ALSO SIGNIFICANTLY LOWER THAN THOSE OF THE CONTROL GROUP (P < 0.001), WHILE THE LOWER SCORES FOR THE YOGA GROUP IN THE LUMBAR GROUP APPROACHED, BUT DID NOT REACH, STATISTICAL SIGNIFICANCE (P = 0.055). THE SCORES FOR INDIVIDUAL DISCS OF YOGA PRACTITIONERS SHOWED SIGNIFICANTLY LESS DEGENERATIVE DISEASE AT THREE DISC LEVELS, C3/C4, L2/L3 AND L3/L4 (P < 0.05). MAGNETIC RESONANCE IMAGING SHOWED THAT THE GROUP OF LONG-TERM PRACTITIONERS OF YOGA STUDIED HAD SIGNIFICANTLY LESS DEGENERATIVE DISC DISEASE THAN A MATCHED CONTROL GROUP.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
6 1439 20 INCREASED GREY MATTER ASSOCIATED WITH LONG-TERM SAHAJA YOGA MEDITATION: A VOXEL-BASED MORPHOMETRY STUDY. OBJECTIVES: TO INVESTIGATE REGIONAL DIFFERENCES IN GREY MATTER VOLUME ASSOCIATED WITH THE PRACTICE OF SAHAJA YOGA MEDITATION. DESIGN: TWENTY THREE EXPERIENCED PRACTITIONERS OF SAHAJA YOGA MEDITATION AND TWENTY THREE NON-MEDITATORS MATCHED ON AGE, GENDER AND EDUCATION LEVEL, WERE SCANNED USING STRUCTURAL MAGNETIC RESONANCE IMAGING AND THEIR GREY MATTER VOLUME WERE COMPARED USING VOXEL-BASED MORPHOMETRY. RESULTS: GREY MATTER VOLUME WAS LARGER IN MEDITATORS RELATIVE TO NON-MEDITATORS ACROSS THE WHOLE BRAIN. IN ADDITION, GREY MATTER VOLUME WAS LARGER IN SEVERAL PREDOMINANTLY RIGHT HEMISPHERIC REGIONS: IN INSULA, VENTROMEDIAL ORBITOFRONTAL CORTEX, INFERIOR TEMPORAL AND PARIETAL CORTICES AS WELL AS IN LEFT VENTROLATERAL PREFRONTAL CORTEX AND LEFT INSULA. NO AREAS WITH LARGER GREY MATTER VOLUME WERE FOUND IN NON-MEDITATORS RELATIVE TO MEDITATORS. CONCLUSIONS: THE STUDY SHOWS THAT LONG-TERM PRACTICE OF SAHAJA YOGA MEDITATION IS ASSOCIATED WITH LARGER GREY MATTER VOLUME OVERALL, AND WITH REGIONAL ENLARGEMENT IN SEVERAL RIGHT HEMISPHERIC CORTICAL AND SUBCORTICAL BRAIN REGIONS THAT ARE ASSOCIATED WITH SUSTAINED ATTENTION, SELF-CONTROL, COMPASSION AND INTEROCEPTIVE PERCEPTION. THE INCREASED GREY MATTER VOLUME IN THESE ATTENTION AND SELF-CONTROL MEDIATING REGIONS SUGGESTS USE-DEPENDENT ENLARGEMENT WITH REGULAR PRACTICE OF THIS MEDITATION.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
7 2720 18 YOGA MEDITATION PRACTITIONERS EXHIBIT GREATER GRAY MATTER VOLUME AND FEWER REPORTED COGNITIVE FAILURES: RESULTS OF A PRELIMINARY VOXEL-BASED MORPHOMETRIC ANALYSIS. HATHA YOGA TECHNIQUES, INCLUDING PHYSICAL POSTURES (ASANAS), BREATHING EXERCISES (PRANAYAMA), AND MEDITATION, INVOLVE THE PRACTICE OF MINDFULNESS. IN TURN, YOGA MEDITATION PRACTICES MAY INDUCE THE STATE OF MINDFULNESS, WHICH, WHEN EVOKED RECURRENTLY THROUGH REPEATED PRACTICE, MAY ACCRUE INTO TRAIT OR DISPOSITIONAL MINDFULNESS. PUTATIVELY, THESE CHANGES MAY BE MEDIATED BY EXPERIENCE-DEPENDENT NEUROPLASTIC CHANGES. THOUGH PRIOR STUDIES HAVE IDENTIFIED DIFFERENCES IN GRAY MATTER VOLUME (GMV) BETWEEN LONG-TERM MINDFULNESS PRACTITIONERS AND CONTROLS, NO STUDIES TO DATE HAVE REPORTED ON WHETHER YOGA MEDITATION IS ASSOCIATED WITH GMV DIFFERENCES. THE PRESENT STUDY INVESTIGATED GMV DIFFERENCES BETWEEN YOGA MEDITATION PRACTITIONERS (YMP) AND A MATCHED CONTROL GROUP (CG). THE YMP GROUP EXHIBITED GREATER GM VOLUME IN FRONTAL, LIMBIC, TEMPORAL, OCCIPITAL, AND CEREBELLAR REGIONS; WHEREAS THE CG HAD NO GREATER REGIONAL GREATER GMV. IN ADDITION, THE YMP GROUP REPORTED SIGNIFICANTLY FEWER COGNITIVE FAILURES ON THE COGNITIVE FAILURES QUESTIONNAIRE (CFQ), THE MAGNITUDE OF WHICH WAS POSITIVELY CORRELATED WITH GMV IN NUMEROUS REGIONS IDENTIFIED IN THE PRIMARY ANALYSIS. LASTLY, GMV WAS POSITIVELY CORRELATED WITH THE DURATION OF YOGA PRACTICE. RESULTS FROM THIS PRELIMINARY STUDY SUGGEST THAT HATHA YOGA PRACTICE MAY BE ASSOCIATED WITH THE PROMOTION OF NEUROPLASTIC CHANGES IN EXECUTIVE BRAIN SYSTEMS, WHICH MAY CONFER THERAPEUTIC BENEFITS THAT ACCRUE WITH REPEATED PRACTICE.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
8 1288 20 GREATER CORTICAL THICKNESS IN ELDERLY FEMALE YOGA PRACTITIONERS-A CROSS-SECTIONAL STUDY. YOGA, A MIND-BODY ACTIVITY THAT REQUIRES ATTENTIONAL ENGAGEMENT, HAS BEEN ASSOCIATED WITH POSITIVE CHANGES IN BRAIN STRUCTURE AND FUNCTION, ESPECIALLY IN AREAS RELATED TO AWARENESS, ATTENTION, EXECUTIVE FUNCTIONS AND MEMORY. NORMAL AGING, ON THE OTHER HAND, HAS ALSO BEEN ASSOCIATED WITH STRUCTURAL AND FUNCTIONAL BRAIN CHANGES, BUT THESE GENERALLY INVOLVE DECREASED COGNITIVE FUNCTIONS. THE AIM OF THIS CROSS-SECTIONAL STUDY WAS TO COMPARE BRAIN CORTICAL THICKNESS (CT) IN ELDERLY YOGA PRACTITIONERS AND A GROUP OF AGE-MATCHED HEALTHY NON-PRACTITIONERS. WE TESTED 21 OLDER WOMEN WHO HAD PRACTICED HATHA YOGA FOR AT LEAST 8 YEARS AND 21 WOMEN NAIVE TO YOGA, MEDITATION OR ANY MIND-BODY INTERVENTIONS WHO WERE MATCHED TO THE FIRST GROUP IN AGE, YEARS OF FORMAL EDUCATION AND PHYSICAL ACTIVITY LEVEL. A T1-WEIGHTED MPRAGE SEQUENCE WAS ACQUIRED FOR EACH PARTICIPANT. YOGA PRACTITIONERS SHOWED SIGNIFICANTLY GREATER CT IN A LEFT PREFRONTAL LOBE CLUSTER, WHICH INCLUDED PORTIONS OF THE LATERAL MIDDLE FRONTAL GYRUS, ANTERIOR SUPERIOR FRONTAL GYRUS AND DORSAL SUPERIOR FRONTAL GYRUS. WE FOUND GREATER CT IN THE LEFT PREFRONTAL CORTEX OF HEALTHY ELDERLY WOMEN WHO TRAINED YOGA FOR A MINIMUM OF 8 YEARS COMPARED WITH WOMEN IN THE CONTROL GROUP.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
9 1354 17 IMMEDIATE EFFECT OF THREE YOGA BREATHING TECHNIQUES ON PERFORMANCE ON A LETTER-CANCELLATION TASK. THE EFFECTS OF THREE YOGA BREATHING PRACTICES WERE EVALUATED ON PERFORMANCE ON A LETTER-CANCELLATION TASK WHICH IS A LEFT-HEMISPHERE DOMINANT TASK. THE THREE YOGA BREATHING PRACTICES (RIGHT, LEFT, AND ALTERNATE NOSTRIL BREATHING) WERE SELECTED BECAUSE UNILATERAL FORCED NOSTRIL BREATHING STIMULATES THE CONTRALATERAL HEMISPHERE. THERE WERE 20 MALE VOLUNTEERS WHOSE AGES RANGED FROM 20 TO 45 YEARS (M AGE=28.4 YR., SD=5.7). ALL SUBJECTS WERE ASSESSED BEFORE AND AFTER FOUR SESSIONS, I.E., RIGHT NOSTRIL YOGA BREATHING, LEFT NOSTRIL YOGA BREATHING, ALTERNATE NOSTRIL YOGA BREATHING, AND BREATH AWARENESS AS A CONTROL. THE LETTER-CANCELLATION TASK SCORES WERE SIGNIFICANTLY IMPROVED, I.E., THERE WERE FEWER ERRORS FOLLOWING RIGHT AND ALTERNATE NOSTRIL YOGA BREATHING (WILCOXON PAIRED SIGNED-RANKS TEST). THE IMPROVED PERFORMANCE MAY BE RELATED TO THE ENHANCEMENT OF CONTRALATERAL HEMISPHERE FUNCTION FOUND WITH SELECTIVE NOSTRIL BREATHING.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
10 1208 27 EXPLORATION OF LOWER FREQUENCY EEG DYNAMICS AND CORTICAL ALPHA ASYMMETRY IN LONG-TERM RAJYOGA MEDITATORS. BACKGROUND: RAJYOGA MEDITATION IS TAUGHT BY PRAJAPITA BRAHMAKUMARIS WORLD SPIRITUAL UNIVERSITY (BRAHMAKUMARIS) AND HAS BEEN FOLLOWED BY MORE THAN ONE MILLION FOLLOWERS ACROSS THE GLOBE. HOWEVER, RARE STUDIES WERE CONDUCTED ON PHYSIOLOGICAL ASPECTS OF RAJYOGA MEDITATION USING ELECTROENCEPHALOGRAPHY (EEG). BAND POWER AND CORTICAL ASYMMETRY WERE NOT STUDIED WITH RAJYOGA MEDITATORS. AIMS: THIS STUDY AIMS TO INVESTIGATE THE EFFECT OF REGULAR MEDITATION PRACTICE ON EEG BRAIN DYNAMICS IN LOW-FREQUENCY BANDS OF LONG-TERM RAJYOGA MEDITATORS. SETTINGS AND DESIGN: SUBJECTS WERE MATCHED FOR AGE IN BOTH GROUPS. LOWER FREQUENCY EEG BANDS WERE ANALYZED IN RESTING AND DURING MEDITATION. MATERIALS AND METHODS: TWENTY-ONE MALE LONG-TERM MEDITATORS (LTMS) AND SAME NUMBER OF CONTROLS WERE SELECTED TO PARTICIPATE IN STUDY AS PAR INCLUSION CRITERIA. SEMI HIGH-DENSITY EEG WAS RECORDED BEFORE AND DURING MEDITATION IN LTM GROUP AND RESTING IN CONTROL GROUP. THE MAIN OUTCOME OF THE STUDY WAS SPECTRAL POWER OF ALPHA AND THETA BANDS AND CORTICAL (HEMISPHERICAL) ASYMMETRY CALCULATED USING BAND POWER. STATISTICAL ANALYSIS: ONE-WAY ANOVA WAS PERFORMED TO FIND THE SIGNIFICANT DIFFERENCE BETWEEN EEG SPECTRAL PROPERTIES OF GROUPS. PEARSON'S CHI-SQUARE TEST WAS USED TO FIND DIFFERENCE AMONG DEMOGRAPHICS DATA. RESULTS: RESULTS REVEAL HIGH-BAND POWER IN ALPHA AND THETA SPECTRA IN MEDITATORS. CORTICAL ASYMMETRY CALCULATED THROUGH EEG POWER WAS ALSO FOUND TO BE HIGH IN FRONTAL AS WELL AS PARIETAL CHANNELS. HOWEVER, NO CORRELATION WAS SEEN BETWEEN THE EXPERIENCE OF MEDITATION (YEARS, HOURS) PRACTICE AND EEG INDICES. CONCLUSION: OVERALL FINDINGS INDICATE CONTRIBUTION OF SMALLER FREQUENCIES (ALPHA AND THETA) WHILE MAINTAINING MEDITATIVE EXPERIENCE. THIS SUGGESTS A POSITIVE IMPACT OF MEDITATION ON FRONTAL AND PARIETAL AREAS OF BRAIN, INVOLVED IN THE PROCESSES OF REGULATION OF SELECTIVE AND SUSTAINED ATTENTION AS WELL AS PROVIDE EVIDENCE ABOUT THEIR INVOLVEMENT IN EMOTION AND COGNITIVE PROCESSING.	2018	

11  525 20 COMPARISON OF EFFECTS OF YOGA & PHYSICAL EXERCISE IN ATHLETES. THE EFFECT OF PRANAYAMA A CONTROLLED BREATHING PRACTICE, ON EXERCISE TESTS WAS STUDIED IN ATHLETES IN TWO PHASES; SUB-MAXIMAL AND MAXIMAL EXERCISE TESTS. AT THE END OF PHASE I (ONE YEAR) BOTH THE GROUPS (CONTROL AND EXPERIMENTAL) ACHIEVED SIGNIFICANTLY HIGHER WORK RATE AND REDUCTION IN OXYGEN CONSUMPTION PER UNIT WORK. THERE WAS A SIGNIFICANT REDUCTION IN BLOOD LACTATE AND AN INCREASE IN P/L RATIO IN THE EXPERIMENTAL GROUP, AT REST. AT THE END OF PHASE II (TWO YEARS), THE OXYGEN CONSUMPTION PER UNIT WORK WAS FOUND TO BE SIGNIFICANTLY REDUCED AND THE WORK RATE SIGNIFICANTLY INCREASED IN THE EXPERIMENTAL GROUP. BLOOD LACTATE DECREASED SIGNIFICANTLY AT REST IN THE EXPERIMENTAL GROUP ONLY. PYRUVATE AND PYRUVATE-LACTATE RATIO INCREASED SIGNIFICANTLY IN BOTH THE GROUPS AFTER EXERCISE AND AT REST IN THE EXPERIMENTAL GROUP. THE RESULTS IN BOTH PHASES SHOWED THAT THE SUBJECTS WHO PRACTISED PRANAYAMA COULD ACHIEVE HIGHER WORK RATES WITH REDUCED OXYGEN CONSUMPTION PER UNIT WORK AND WITHOUT INCREASE IN BLOOD LACTATE LEVELS. THE BLOOD LACTATE LEVELS WERE SIGNIFICANTLY LOW AT REST.	1994	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
12 1814 20 PROGRESSIVE INCREASE IN CRITICAL FLICKER FUSION FREQUENCY FOLLOWING YOGA TRAINING. THE CRITICAL FLICKER FUSION FREQUENCY (CFF) IS THE FREQUENCY AT WHICH A FLICKERING STIMULUS IS PERCEIVED TO BE STEADY, WITH HIGHER VALUES SUGGESTING GREATER PERCEPTUAL ACCURACY. THE CFF WAS MEASURED IN TWO AGE-MATCHED GROUPS OF HEALTHY MALE VOLUNTEERS WHOSE AGES RANGED FROM 25 TO 39 YEARS, WITH 18 SUBJECTS IN EACH GROUP. AFTER BASELINE ASSESSMENTS ONE GROUP (YOGA GROUP) RECEIVED YOGA TRAINING, WHILE THE OTHER GROUP (CONTROL GROUP) CARRIED ON WITH THEIR ROUTINE ACTIVITIES. YOGA PRACTICES INCLUDED ASANAS, PRANAYAMAS, KRIYAS, MEDITATION, DEVOTIONAL SESSIONS AND LECTURES ON THE THEORY OF YOGA. AFTER 10 DAYS NEITHER GROUP SHOWED A CHANGE IN CFF. HOWEVER, AT 20 AND AT 30 DAYS THE YOGA GROUP SHOWED SIGNIFICANT INCREASES IN CFF BY 11.1% AND 14.9%, RESPECTIVELY (TWO FACTOR ANOVA, TUKEY MULTIPLE COMPARISON TEST). THE CONTROL GROUP SHOWED NO CHANGE AT THE DAY 20 AND DAY 30 FOLLOWUP.	1997	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
13 2510 23 YOGA BREATHING THROUGH A PARTICULAR NOSTRIL INCREASES SPATIAL MEMORY SCORES WITHOUT LATERALIZED EFFECTS. UNINOSTRIL BREATHING FACILITATES THE PERFORMANCE ON SPATIAL AND VERBAL COGNITIVE TASKS, SAID TO BE RIGHT AND LEFT BRAIN FUNCTIONS, RESPECTIVELY. SINCE HEMISPHERIC MEMORY FUNCTIONS ARE ALSO KNOWN TO BE LATERALIZED, THE PRESENT STUDY ASSESSED THE EFFECTS OF UNINOSTRIL BREATHING ON THE PERFORMANCE IN VERBAL AND SPATIAL MEMORY TESTS. SCHOOL CHILDREN (N = 108 WHOSE AGES RANGED FROM 10 TO 17 YEARS) WERE RANDOMLY ASSIGNED TO FOUR GROUPS. EACH GROUP PRACTICED A SPECIFIC YOGA BREATHING TECHNIQUE: (I) RIGHT NOSTRIL BREATHING, (II) LEFT NOSTRIL BREATHING, (III) ALTERNATE NOSTRIL BREATHING, OR (IV) BREATH AWARENESS WITHOUT MANIPULATION OF NOSTRILS. THESE TECHNIQUES WERE PRACTICED FOR 10 DAYS. VERBAL AND SPATIAL MEMORY WAS ASSESSED INITIALLY AND AFTER 10 DAYS. AN AGE-MATCHED CONTROL GROUP OF 27 WERE SIMILARLY ASSESSED. ALL 4 TRAINED GROUPS SHOWED A SIGNIFICANT INCREASE IN SPATIAL TEST SCORES AT RETEST, BUT THE CONTROL GROUP SHOWED NO CHANGE. AVERAGE INCREASE IN SPATIAL MEMORY SCORES FOR THE TRAINED GROUPS WAS 84%. IT APPEARS YOGA BREATHING INCREASES SPATIAL RATHER THAN VERBAL SCORES, WITHOUT A LATERALIZED EFFECT.	1997	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
14 1134 21 EFFICACY OF YOGA IN PREGNANT WOMEN WITH ABNORMAL DOPPLER STUDY OF UMBILICAL AND UTERINE ARTERIES. TO STUDY THE EFFICACY OF YOGA ON THE OUTCOME OF COMPLICATED PREGNANCY, 121 WOMEN ATTENDING ANTENATAL CLINIC AT GUNASHEELA SURGICAL AND MATERNITY HOSPITAL (GSMH) IN BANGALORE, INDIA, WERE ENROLLED BETWEEN 18-20 WEEKS OF PREGNANCY IN A PROSPECTIVE, MATCHED, OBSERVATIONAL STUDY. SIXTY-EIGHT WOMEN WERE IN THE YOGA GROUP AND 53 WOMEN IN THE CONTROL GROUP. WOMEN WERE MATCHED FOR AGE, GRAVIDA AND DOPPLER VELOCIMETRY SCORES OF UMBILICAL AND UTERINE ARTERIES. YOGA PRACTICES INCLUDING PHYSICAL POSTURES, BREATHING AND MEDITATION WERE PRACTISED BY THE YOGA GROUP, ONE HOUR DAILY, FROM THE DATE OF ENTRY INTO THE STUDY UNTIL DELIVERY. THE CONTROL GROUP WALKED HALF AN HOUR TWICE A DAY DURING THE STUDY PERIOD. COMPLIANCE IN BOTH THE GROUPS WAS ENSURED. IN BABIES THE BIRTH-WEIGHT IS SIGNIFICANTLY HIGHER (P < 0.018) IN THE YOGA GROUP (2.78 +/- 0.52 KG), COMPARED TO THE CONTROL GROUP (2.55 +/- 0.52 KG). OCCURRENCE OF COMPLICATIONS OF PREGNANCY (PREGNANCY-INDUCED HYPERTENSION, INTRAUTERINE GROWTH RETARDATION, PRE-TERM DELIVERY) SHOWS LOWER TRENDS IN YOGA GROUP.	2005	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
15  751 11 EFFECT OF SHORT TERM YOGA PRACTICE ON VENTILATORY FUNCTION TESTS. TWENTYFIVE NORMAL MALE VOLUNTEERS UNDERGOING A TEN WEEKS COURSE IN THE PRACTICE OF YOGA HAVE BEEN STUDIED BY SOME PARAMETERS OF VENTILATORY FUNCTIONS TESTS. THE OBSERVATIONS RECORDED AT THE END OF TEN WEEKS OF THE COURSE HAVE SHOWN IMPROVED VENTILATORY FUNCTIONS IN THE FORM OF LOWERED RESPIRATORY RATE, INCREASED FORCED VITAL CAPACITY, FEV1, MAXIMUM BREATHING CAPACITY AND BREATH HOLDING TIME, WHILE TIDAL VOLUME AND %FEV1, DID NOT REVEAL ANY SIGNIFICANT CHANGE. THUS, A COMBINED PRACTICE OF YOGA SEEMS TO BE BENEFICIAL ON RESPIRATORY EFFICIENCY.	1988	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
16 1641 17 MONITORING THE NEURAL ACTIVITY OF THE STATE OF MENTAL SILENCE WHILE PRACTICING SAHAJA YOGA MEDITATION. OBJECTIVE: TO IDENTIFY THE NEURAL CORRELATES OF THE STATE OF MENTAL SILENCE AS EXPERIENCED THROUGH SAHAJA YOGA MEDITATION. DESIGN: NINETEEN EXPERIENCED MEDITATORS UNDERWENT FUNCTIONAL MAGNETIC RESONANCE IMAGING DURING THREE SHORT CONSECUTIVE MEDITATION PERIODS, CONTRASTED WITH A CONTROL RELAXATION CONDITION. RESULTS: RELATIVE TO BASELINE, AT THE BEGINNING OF THE MEDITATION SESSIONS THERE WAS A SIGNIFICANT INCREASE OF ACTIVATION IN BILATERAL INFERIOR FRONTAL AND TEMPORAL REGIONS. ACTIVATION BECAME PROGRESSIVELY MORE REDUCED WITH DEEPER MEDITATION STAGES AND IN THE LAST MEDITATION SESSION IT BECAME LOCALIZED TO THE RIGHT INFERIOR FRONTAL CORTEX/ RIGHT INSULA AND RIGHT MIDDLE/SUPERIOR TEMPORAL CORTEX. FURTHERMORE, RIGHT INFERIOR FRONTAL ACTIVATION WAS DIRECTLY ASSOCIATED WITH THE SUBJECTIVE DEPTH OF THE MENTAL SILENCE EXPERIENCE. CONCLUSIONS: MEDITATORS APPEAR TO PASS THROUGH AN INITIAL INTENSE NEURAL SELF-CONTROL PROCESS NECESSARY TO SILENCE THEIR MIND. AFTER THIS THEY EXPERIENCE RELATIVELY REDUCED BRAIN ACTIVATION CONCOMITANT WITH THE DEEPENING OF THE STATE OF MENTAL SILENCE OVER RIGHT INFERIOR FRONTAL CORTEX, PROBABLY REFLECTING AN EFFORTLESS PROCESS OF ATTENTIONAL CONTEMPLATION ASSOCIATED WITH THIS STATE.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
17 1916 20 ROLE OF TEMPORALIS MUSCLE OVER ACTIVITY IN CHRONIC TENSION TYPE HEADACHE: EFFECT OF YOGA BASED MANAGEMENT. THE ROLE OF CENTRAL VERSUS PERIPHERAL MECHANISMS HAS ALWAYS BEEN QUESTIONED WHILE EXPLAINING THE ETIOPATHOGENESIS OF CHRONIC TENSION TYPE HEADACHE (CTTH). THE FOLLOWING STUDY WAS DONE TO STUDY THE ROLE OF MUSCLE SPASM IN CTTH. 15 PATIENTS OF CTTH AND 7 AGE MATCHED CONTROLS WERE INCLUDED IN THE STUDY AND THEIR M. TEMPORALIS EMG WAS RECORDED FOR ONE MINUTE EACH DURING REST, MENTAL ACTIVITY AND MAXIMAL VOLUNTARY CONTRACTION AND SUBJECTIVE PAIN SCORING WAS DONE BY VISUAL ANALOGUE SCALE. THE RESULTS REVEALED SIGNIFICANT OVERACTIVITY OF M.TEMPORALIS IN CTTH PATIENTS AT REST WHEN COMPARED WITH CONTROL SUBJECTS (P = 0.01 AND 0.03 LEFT AND RIGHT SIDE RESPECTIVELY). AFTER RESPECTIVE INTERVENTIONS NAMELY NON STEROIDAL ANTI INFLAMMATORY DRUGS, BOTULINUM TOXIN INJECTIONS AND YOGIC LIFE STYLE COURSE, THE EMG RECORDS REVEALED DECREASE IN THE MEAN EMG AMPLITUDE OF M. TEMPORALIS DURING REST AND MENTAL ACTIVITY MORE SIGNIFICANTLY AFTER YOGA BASED INTERVENTIONS (P = 0.03) AND SUBJECTIVE PAIN SCORES DECREASED FROM 7.00 +/- 2.10 TO 2.00 +/- 1.26 (P = 0.02) SUPPORTING THE BENEFICIAL EFFECT OF SUCH NON INVASIVE TECHNIQUES.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
18  821 14 EFFECT OF YOGA ON EXERCISE TOLERANCE IN NORMAL HEALTHY VOLUNTEERS. TWELVE NORMAL HEALTHY VOLUNTEERS (6 MALES AND 6 FEMALES) UNDERGOING YOGA TRAINING FOR 90 DAYS WERE STUDIED FOR THE EFFECT OF YOGA ON EXERCISE TOLERANCE. THEIR AGES RANGED FROM 18 TO 28 YEARS. THE VOLUNTEERS WERE TAUGHT ONLY PRANAYAMA FOR THE FIRST 20 DAYS AND LATER ON YOGIC ASANAS WERE ADDED. SUB-MAXIMAL EXERCISE TOLERANCE TEST WAS DONE ON A MOTORIZED TREADMILL BY USING BALKE'S MODIFIED PROTOCOL, INITIALLY, AFTER 20 DAYS (PHASE-I) AND AFTER 90 DAYS OF YOGA TRAINING (PHASE-II). PYRUVATE AND LACTATE IN VENOUS BLOOD AND BLOOD GASES IN CAPILLARY BLOOD WERE ESTIMATED IMMEDIATELY BEFORE AND AFTER THE EXERCISE. MINUTE VENTILATION AND OXYGEN CONSUMPTION WERE ESTIMATED BEFORE AND DURING THE TEST. POST EXERCISE BLOOD LACTATE WAS ELEVATED SIGNIFICANTLY DURING INITIAL AND PHASE-I, BUT NOT IN PHASE-II. THERE WAS SIGNIFICANT REDUCTION OF MINUTE VENTILATION AND OXYGEN CONSUMPTION ONLY IN MALES IN PHASE-I AND II AT THE TIME WHEN THE VOLUNTEERS REACHED THEIR 80% OF THE PREDICTED HEART RATE. FEMALE VOLUNTEERS WERE ABLE TO GO TO HIGHER LOADS OF EXERCISE IN PHASE-I AND II.	1986	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
19 1938 24 ROLE OF YOGA ON CARDIC AUTONOMIC FUNCTION TESTS AND COGNITION IN TYPE 2 DIABETES. ACCORDING TO INTERNATIONAL DIABETIC FEDERATION, TYPE 2 DIABETIC POPULATION IS ON THE RISE GLOBALLY AND COGNITIVE DECLINE IS ONE OF THE COMPLICATIONS SEEN IN TYPE 2 DIABETES. THE PRESENT STUDY IS AIMED AT EXPLORING THE ROLE OF REGULAR PRACTICE OF YOGA ON COGNITION IN TYPE 2 DIABETES AND ALSO TO STUDY THE RELATION BETWEEN THE COGNITION AND FUNCTIONAL STATUS OF AUTONOMIC NERVOUS SYSTEM BY CONSIDERING THE CARDIAC AUTONOMIC (CAN) FUNCTION TESTS. TEN TYPE 2 DIABETIC SUBJECTS OF BOTH THE SEX, AGED BETWEEN 35-55 YEARS, WHO PRACTICED YOGA FOR A PERIOD OF SIX MONTHS AT YOGI VEMANA YOGA RESEARCH INSTITUTE WERE RECRUITED AS TEST GROUP. AGE AND SEX MATCHED TEN TYPE 2 DIABETIC SUBJECTS WERE RECRUITED AS CONTROL GROUP; BOTH THE GROUP SUBJECTS ARE ON ORAL HYPOGLYCEMIC AGENTS. GLYCOSYLATED HEMOGLOBIN CONCENTRATION WAS ESTIMATED WITH BIO-RAD INSTRUMENT, COGNITION WAS ASSESSED WITH ADDENBROOKE'S COGNITIVE EXAMINATION REVISED BATTERY AND CARDIAC AUTONOMIC FUNCTION TESTS WERE ALSO CONDUCTED. UNPAIRED STUDENT T TEST WAS PERFORMED AND P<0.05 IS CONSIDERED STATISTICALLY SIGNIFICANT. THE MEAN HBA1C CONCENTRATION IN CONTROL AND TEST GROUP SUBJECTS IS 7.8+/-1.84 AND 6.9+/-0.4% (P=0.03) RESPECTIVELY. MEAN COGNITIVE SCORES IN TEST AND CONTROL GROUP SUBJECTS ARE 93+/-4.5 AND 85+/-4.0 (P=0.008) RESPECTIVELY. CAN TEST RESULTS DIDN'T SHOWED ANY SIGNIFICANCE BETWEEN THE TEST AND CONTROL GROUP. BUT CAN FUNCTIONS ARE AFFECTED IN BOTH THE GROUPS. REGULAR PRACTICE OF YOGA IN COMBINATION WITH ORAL HYPOGLYCEMIC AGENTS HAS A POSITIVE EFFECT ON COGNITION IN TYPE 2 DIABETES.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
20  436 17 CARDIORESPIRATORY AND METABOLIC CHANGES DURING YOGA SESSIONS: THE EFFECTS OF RESPIRATORY EXERCISES AND MEDITATION PRACTICES. THE NOVELTY OF THIS STUDY WAS TO INVESTIGATE THE CHANGES IN CARDIORESPIRATORY AND METABOLIC INTENSITY BROUGHT ABOUT BY THE PRACTICE OF PRANAYAMAS (BREATHING EXERCISES OF YOGA) AND MEDITATION DURING THE SAME HATHA-YOGA SESSION. THE TECHNIQUE APPLIED WAS THE ONE ADVOCATED BY THE HATHA-YOGA SYSTEM. NINE YOGA INSTRUCTORS-FIVE FEMALES AND FOUR MALES, MEAN AGE OF 44+/-11, 6, WERE SUBJECTED TO ANALYSIS OF THE GASES EXPIRED DURING THREE DISTINCT PERIODS OF 30 MIN: REST, RESPIRATORY EXERCISES AND MEDITATIVE PRACTICE. A METABOLIC OPEN CIRCUIT COMPUTERIZED SYSTEM WAS APPLIED (VO2000, MEDGRAPHICS-USA). THE OXYGEN UPTAKE (VO(2)) AND THE CARBON DIOXIDE OUTPUT (VCO(2)) WERE STATISTICALLY DIFFERENT (P <OR= 0.05) DURING MEDITATION AND PRANAYAMA PRACTICES WHEN COMPARED WITH REST. THE HEART RATE ALSO SUFFERED RELEVANT REDUCTIONS WHEN RESULTS AT REST WERE COMPARED WITH THOSE DURING MEDITATION. A SMALLER PROPORTION OF LIPIDS WAS METABOLIZED DURING MEDITATION PRACTICE COMPARED WITH REST. THE RESULTS SUGGEST THAT THE MEDITATION USED IN THIS STUDY REDUCES THE METABOLIC RATE WHEREAS THE SPECIFIC PRANAYAMA TECHNIQUE IN THIS STUDY INCREASES IT WHEN COMPARED WITH THE REST STATE.	2008