1  889 60 EFFECT OF YOGA-BASED AND FORCED UNINOSTRIL BREATHING ON THE AUTONOMIC NERVOUS SYSTEM. SOME REPORTS HAVE DESCRIBED THE EFFECTS OF FORCED UNINOSTRIL BREATHING ON AUTONOMIC ACTIVITY AS SEX-SPECIFIC, WHILE OTHER REPORTS DESCRIBED SELECTIVE EFFECTS OF BREATHING THROUGH A SPECIFIC NOSTRIL ON THE TWO DIVISIONS OF THE AUTONOMIC NERVOUS SYSTEM, IRRESPECTIVE OF SEX. THERE ARE ALSO YOGA BREATHING TECHNIQUES WHICH INVOLVE VOLUNTARY UNINOSTRIL BREATHING. THESE TECHNIQUES ALSO INFLUENCED THE AUTONOMIC ACTIVITY BASED ON THE PATENT NOSTRIL RATHER THAN SEX. THESE DESCRIPTIONS WERE IN LINE WITH EXPERIENTIAL OBSERVATIONS OF THE ANCIENT SAGES DESCRIBED IN CLASSICAL YOGA TEXTS. THIS PAPER SUMMARIZES THESE PERSPECTIVES ON UNINOSTRIL BREATHING.	2003	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
2 1810 23 PROCESSING OF PROPRIOCEPTIVE AND VESTIBULAR BODY SIGNALS AND SELF-TRANSCENDENCE IN ASHTANGA YOGA PRACTITIONERS. IN THE ROD AND FRAME TEST (RFT), PARTICIPANTS ARE ASKED TO SET A TILTED VISUAL LINEAR MARKER (I.E., A ROD), EMBEDDED IN A SQUARE, TO THE SUBJECTIVE VERTICAL, IRRESPECTIVE OF THE SURROUNDING FRAME. PEOPLE NOT INFLUENCED BY THE FRAME TILT ARE DEFINED AS FIELD-INDEPENDENT, WHILE PEOPLE BIASED IN THEIR ROD VERTICALITY PERCEPTION ARE FIELD-DEPENDENT. PERFORMING RFT REQUIRES THE INTEGRATION OF PROPRIOCEPTIVE, VESTIBULAR AND VISUAL SIGNALS WITH THE LATTER ACCOUNTING FOR FIELD-DEPENDENCY. STUDIES INDICATE THAT MOTOR EXPERTS IN BODY-RELATED, BALANCE-IMPROVING DISCIPLINES TEND TO BE FIELD-INDEPENDENT, I.E., BETTER AT VERTICALITY PERCEPTION, SUGGESTING THAT PROPRIOCEPTIVE AND VESTIBULAR EXPERTISE ACQUIRED BY SUCH EXERCISE MAY WEAKEN THE INFLUENCE OF IRRELEVANT VISUAL SIGNALS. WHAT REMAINS UNKNOWN IS WHETHER THE EFFECT OF BODY-RELATED EXPERTISE IN WEIGHTING PERCEPTUAL INFORMATION MIGHT ALSO BE MEDIATED BY PERSONALITY TRAITS, IN PARTICULAR THOSE INDEXING SELF-FOCUSING ABILITIES. TO EXPLORE THIS ISSUE, WE TESTED FIELD-DEPENDENCY IN A CLASS OF BODY EXPERTS, NAMELY YOGA PRACTITIONERS AND IN NON-EXPERT PARTICIPANTS. MOREOVER WE EXPLORED ANY LINK BETWEEN PERFORMANCE ON RFT AND SELF-TRANSCENDENCE (ST), A COMPLEX PERSONALITY CONSTRUCT, WHICH REFERS TO TENDENCY TO EXPERIENCE SPIRITUAL FEELINGS AND IDEAS. AS EXPECTED, YOGA PRACTITIONERS (I) WERE MORE ACCURATE IN ASSESSING THE ROD'S VERTICALITY ON THE RFT, AND (II) EXPRESSED SIGNIFICANTLY HIGHER ST. INTERESTINGLY, THE PERFORMANCE IN THESE TWO TESTS WAS NEGATIVELY CORRELATED. MORE SPECIFICALLY, WHEN ASKED TO PROVIDE VERTICALITY JUDGMENTS, HIGHLY SELF-TRANSCENDENT YOGA PRACTITIONERS WERE SIGNIFICANTLY LESS INFLUENCED BY A MISLEADING VISUAL CONTEXT. OUR RESULTS SUGGEST THAT BEING HIGHLY SELF-TRANSCENDENT MAY ENABLE YOGA PRACTITIONERS TO OPTIMIZE VERTICALITY JUDGMENT TASKS BY RELYING MORE ON INTERNAL (VESTIBULAR AND PROPRIOCEPTIVE) SIGNALS COMING FROM THEIR OWN BODY, RATHER THAN ON EXTEROCEPTIVE, VISUAL CUES.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
3 1695 21 P300 FOLLOWING FOUR VOLUNTARILY REGULATED YOGA BREATHING PRACTICES AND BREATH AWARENESS. ATTENTION WAS INFLUENCED BY YOGA BREATHING IN PREVIOUSLY PUBLISHED RESEARCH. EACH YOGA BREATHING PRACTICE UNIQUELY MODIFIES SPECIFIC BREATH CHARACTERISTICS. DIFFERENCES IN THE STUDY DESIGNS, ASSESSMENT METHODS AND INTERVENTIONS RESULTED IN DIFFICULTY IN COMPARING EFFECTS BETWEEN YOGA BREATHING PRACTICES. THIS STUDY AIMED (I) TO COMPARE FOUR YOGA BREATHING PRACTICES ON ATTENTION USING AN AUDITORY ODDBALL TASK AND (II) TO DETERMINE CARDIAC AUTONOMIC ACTIVITY ASSOCIATED WITH ATTENTION USING HEART RATE VARIABILITY. P300 EVENT RELATED POTENTIAL WAS RECORDED SIMULTANEOUSLY WITH HEART RATE VARIABILITY BEFORE AND AFTER 18-MINUTE PERIODS EACH OF (I) HIGH FREQUENCY YOGA BREATHING (WITH INCREASED BREATH FREQUENCY), (II) BELLOWS YOGA BREATHING (WITH INCREASED DEPTH OF RESPIRATION), (III) ALTERNATE NOSTRIL YOGA BREATHING (WITH ALTERNATE NOSTRIL PATENCY), (IV) BUMBLEBEE YOGA BREATHING (WITH PROLONGED EXHALE), (V) BREATH AWARENESS (WITH ATTENTION TO THE BREATH) AND (VI) QUIET SEATED REST AS CONTROL IN 38 YOGA EXPERIENCED MALES (AVERAGE AGE +/- SD; 24.08 +/- 4.01 YEARS). THE SIX SESSIONS WERE ON SEPARATE, RANDOMLY ALLOCATED DAYS. THE P300 PEAK AMPLITUDE RECORDED AT PZ WAS SIGNIFICANTLY INCREASED AFTER FOUR YOGA BREATHING PRACTICES (BONFERRONI ADJUSTED POST-HOC TESTS, REPEATED MEASURES ANOVA). NO SIGNIFICANT CHANGES WERE NOTED IN HEART RATE VARIABILITY FOLLOWING YOGA BREATHING OR CONTROL SESSIONS. THESE FINDINGS SUGGEST THAT THE FOUR YOGA BREATHING PRACTICES INCREASE THE ATTENTIONAL NEURAL RESOURCES ENGAGED FOR THIS AUDITORY ODDBALL TASK, IRRESPECTIVE OF THE CHARACTERISTIC OF BREATH UNIQUELY REGULATED IN THE FOUR YOGA BREATHING PRACTICES.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
4 1498 16 INTRAOCULAR PRESSURE CHANGES AND OCULAR BIOMETRY DURING SIRSASANA (HEADSTAND POSTURE) IN YOGA PRACTITIONERS. PURPOSE: TO STUDY THE INTRAOCULAR PRESSURE (IOP) CHANGES IN SIRSASANA (HEADSTAND POSTURE) DONE BY EXPERIENCED YOGA PRACTITIONERS AND CORRELATE THE OCULAR BIOMETRIC PARAMETERS WITH THE IOP CHANGES, AND TO SCREEN FOR THE PREVALENCE OF OCULAR HYPERTENSION IN THIS GROUP OF SUBJECTS. DESIGN: PROSPECTIVE CASE OBSERVATIONAL SERIES. PARTICIPANTS: SEVENTY-FIVE SUBJECTS (50 ASIAN INDIANS AND 25 CAUCASIANS) FROM A YOGA TRAINING INSTITUTE VOLUNTEERED FOR THE STUDY. METHODS: ALL PARTICIPANTS UNDERWENT A DETAILED OPHTHALMIC EXAMINATION ALONG WITH OCULAR BIOMETRY AND CORNEAL PACHYMETRY. INTRAOCULAR PRESSURE WAS RECORDED USING A TONOPEN BEFORE, DURING, AND AFTER THE SIRSASANA. CHANGES WERE COMPARED USING THE PAIRED T TEST. AGE, AXIAL LENGTH, ANTERIOR CHAMBER DEPTH, LENS THICKNESS, CORNEAL CURVATURE, CORNEAL THICKNESS, RACE, AND THE LENGTH OF TIME FOR WHICH THE PRACTITIONER WAS PERFORMING YOGA WERE CORRELATED WITH THE INDUCED IOP DIFFERENCE IN A RANDOMLY SELECTED EYE USING PEARSON'S CORRELATION COEFFICIENT WITH BONFERRONI CORRECTION FOR MULTIPLE COMPARISONS. MAIN OUTCOME MEASURES: OCULAR BIOMETRY AND INDUCED IOP DIFFERENCE. RESULTS: THE MEAN INCREASE IN IOP AT BASELINE AND IMMEDIATELY AFTER ASSUMING SIRSASANA WAS 15.1+/-4.1 MMHG (R = 0.07; P = 0.999) AND AFTER 5 MINUTES WAS 15.8+/-4.6 MMHG (R = -0.25; P = 0.357). THE INDUCED INCREASE IN IOP DURING THE POSTURE WAS TWICE THE BASELINE IOP. THERE WAS NO CORRELATION BETWEEN AGE, OCULAR BIOMETRY, AND ULTRASOUND PACHYMETRY WHEN COMPARED WITH THE INDUCED IOP DIFFERENCE. ONE SUBJECT (1.33%) WAS FOUND TO HAVE BASELINE IOP OF MORE THAN 21 MMHG. CONCLUSION: THERE WAS A UNIFORM 2-FOLD INCREASE IN THE IOP DURING SIRSASANA, WHICH WAS MAINTAINED DURING THE POSTURE IN ALL AGE GROUPS IRRESPECTIVE OF THE OCULAR BIOMETRY AND ULTRASOUND PACHYMETRY. WE DID NOT DEMONSTRATE A HIGHER PREVALENCE OF OCULAR HYPERTENSIVES IN THIS COHORT OF YOGA PRACTITIONERS NOR DID THE RISK FACTORS CONTRIBUTING TO GLAUCOMA SHOW ANY CORRELATION WITH MAGNITUDE OF IOP RAISE DURING THE POSTURE.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
5 1728 15 PERFORMANCE ON PSYCHOMOTOR TASKS FOLLOWING TWO YOGA-BASED RELAXATION TECHNIQUES. PREVIOUSLY CYCLIC MEDITATION AND SUPINE REST HAVE BEEN SHOWN TO IMPROVE PERFORMANCE IN A LETTER CANCELLATION TASK REQUIRING ATTENTION, VISUAL SCANNING, AND MOTOR SPEED. THE PRESENT STUDY ASSESSED THE PERFORMANCE IN 57 VOLUNTEERS (ALL MALE, M AGE = 26.5 YR., SD = 4.6) IN THREE TASKS, VIZ., A DIGIT-LETTER SUBSTITUTION TASK (DLST), A LETTER-COPYING TASK, AND A CIRCLE-DOTTING TASK. THE DLST ASSESSED ATTENTION AND SPEED OF INFORMATION PROCESSING, WHILE THE OTHER 2 TESTS ASSESSED MOTOR SPEED. EACH PARTICIPANT WAS ASSESSED BEFORE AND AFTER THREE TYPES OF SESSIONS: CYCLIC MEDITATION, SUPINE REST, AND CONTROL (NO INTERVENTION). DLST SCORES AND SCORES FOR LETTER-COPYING AND CIRCLE-DOTTING TASKS IMPROVED SIGNIFICANTLY AFTER CYCLIC MEDITATION; THE SAME SCORES ALSO IMPROVED AFTER SUPINE REST. THERE WAS NO CHANGE AFTER THE NO-INTERVENTION/CONTROL SESSION. FROM THE RESULTS IT WAS DIFFICULT TO CONCLUDE WHETHER IMPROVED DLST SCORES AFTER CYCLIC MEDITATION WERE DUE TO BETTER INFORMATION PROCESSING SPEED OR IMPROVED MOTOR SPEED.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
6 1354 18 IMMEDIATE EFFECT OF THREE YOGA BREATHING TECHNIQUES ON PERFORMANCE ON A LETTER-CANCELLATION TASK. THE EFFECTS OF THREE YOGA BREATHING PRACTICES WERE EVALUATED ON PERFORMANCE ON A LETTER-CANCELLATION TASK WHICH IS A LEFT-HEMISPHERE DOMINANT TASK. THE THREE YOGA BREATHING PRACTICES (RIGHT, LEFT, AND ALTERNATE NOSTRIL BREATHING) WERE SELECTED BECAUSE UNILATERAL FORCED NOSTRIL BREATHING STIMULATES THE CONTRALATERAL HEMISPHERE. THERE WERE 20 MALE VOLUNTEERS WHOSE AGES RANGED FROM 20 TO 45 YEARS (M AGE=28.4 YR., SD=5.7). ALL SUBJECTS WERE ASSESSED BEFORE AND AFTER FOUR SESSIONS, I.E., RIGHT NOSTRIL YOGA BREATHING, LEFT NOSTRIL YOGA BREATHING, ALTERNATE NOSTRIL YOGA BREATHING, AND BREATH AWARENESS AS A CONTROL. THE LETTER-CANCELLATION TASK SCORES WERE SIGNIFICANTLY IMPROVED, I.E., THERE WERE FEWER ERRORS FOLLOWING RIGHT AND ALTERNATE NOSTRIL YOGA BREATHING (WILCOXON PAIRED SIGNED-RANKS TEST). THE IMPROVED PERFORMANCE MAY BE RELATED TO THE ENHANCEMENT OF CONTRALATERAL HEMISPHERE FUNCTION FOUND WITH SELECTIVE NOSTRIL BREATHING.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
7  458 17 CHANGES IN P300 FOLLOWING TWO YOGA-BASED RELAXATION TECHNIQUES. CYCLIC MEDITATION (CM) IS A TECHNIQUE THAT COMBINES "STIMULATING" AND "CALMING" PRACTICES, BASED ON A STATEMENT IN ANCIENT YOGA TEXTS SUGGESTING THAT SUCH A COMBINATION MAY BE ESPECIALLY HELPFUL TO REACH A STATE OF MENTAL EQUILIBRIUM. THE CHANGES IN THE PEAK LATENCY AND PEAK AMPLITUDE OF P300 AUDITORY EVENT-RELATED POTENTIALS WERE STUDIED BEFORE AND AFTER THE PRACTICE OF CYCLIC MEDITATION COMPARED TO AN EQUAL DURATION OF SUPINE REST IN 42 VOLUNTEERS (GROUP MEAN AGE +/- SD, 27 +/- 6.3 YEARS), FROM FZ, CZ, AND PZ ELECTRODE SITES REFERENCED TO LINKED EARLOBES. THE SESSIONS WERE ONE DAY APART AND THE ORDER WAS ALTERNATED. THERE WAS REDUCTION IN THE PEAK LATENCIES OF P300 AFTER CYCLIC MEDITATION AT FZ, CZ, AND PZ COMPARED TO THE "PRE" VALUES. A SIMILAR TREND OF REDUCTION IN P300 PEAK LATENCIES AT FZ, CZ, AND PZ WAS ALSO OBSERVED AFTER SUPINE REST, COMPARED TO THE RESPECTIVE "PRE" VALUES, ALTHOUGH THE MAGNITUDE OF CHANGE IN EACH CASE WAS LESS AFTER SUPINE REST COMPARED TO AFTER CYCLIC MEDITATION. THE P300 PEAK AMPLITUDES AFTER CM WERE HIGHER AT FZ, CZ, AND PZ SITES COMPARED TO THE "PRE" VALUES. IN CONTRAST, NO SIGNIFICANT CHANGES WERE OBSERVED IN THE P300 PEAK AMPLITUDES AT FZ, CZ, AND PZ AFTER SUPINE REST COMPARED TO THE RESPECTIVE "PRE" STATE. THE PRESENT RESULTS SUPPORT THE IDEA THAT "CYCLIC" MEDITATION ENHANCES COGNITIVE PROCESSES UNDERLYING THE GENERATION OF THE P300.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
8  457 18 CHANGES IN P300 FOLLOWING ALTERNATE NOSTRIL YOGA BREATHING AND BREATH AWARENESS. THIS STUDY ASSESSED THE EFFECT OF ALTERNATE NOSTRIL YOGA BREATHING (NADISUDDHI PRANAYAMA) ON P300 AUDITORY EVOKED POTENTIALS COMPARED TO A SESSION OF BREATH AWARENESS OF EQUAL DURATION, IN 20 MALE ADULT VOLUNTEERS WHO HAD AN EXPERIENCE OF YOGA BREATHING PRACTICES FOR MORE THAN THREE MONTHS. PEAK AMPLITUDES AND PEAK LATENCIES OF THE P300 WERE ASSESSED BEFORE AND AFTER THE RESPECTIVE SESSIONS. THERE WAS A SIGNIFICANT INCREASE IN THE P300 PEAK AMPLITUDES AT FZ, CZ, AND PZ AND A SIGNIFICANT DECREASE IN THE PEAK LATENCY AT FZ ALONE FOLLOWING ALTERNATE NOSTRIL YOGA BREATHING. FOLLOWING BREATH AWARENESS THERE WAS A SIGNIFICANT INCREASE IN THE PEAK AMPLITUDE OF P300 AT CZ. THIS SUGGESTS THAT ALTERNATE NOSTRIL YOGA BREATHING POSITIVELY INFLUENCES COGNITIVE PROCESSES WHICH ARE REQUIRED FOR SUSTAINED ATTENTION AT DIFFERENT SCALP SITES (FRONTAL, VERTEX AND PARIETAL), WHEREAS BREATH AWARENESS BRINGS ABOUT CHANGES AT THE VERTEX ALONE.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
9 1355 14 IMMEDIATE EFFECT OF TWO YOGA-BASED RELAXATION TECHNIQUES ON ATTENTION IN CHILDREN. AIMS: TO INVESTIGATE THE EFFECT OF TWO YOGA-BASED RELAXATION TECHNIQUES, NAMELY, CYCLIC MEDITATION (CM) AND SUPINE REST (SR), USING THE SIX LETTER CANCELLATION TASK (SLCT). MATERIALS AND METHODS: THE SUBJECTS CONSISTED OF 208 SCHOOL STUDENTS, (132 BOYS, 76 GIRLS) IN THE AGE RANGE OF 13 - 16 YEARS. THE SUBJECTS WERE ASSESSED ON SLCT BEFORE AND IMMEDIATELY AFTER BOTH YOGA-BASED RELAXATION TECHNIQUES. RESULTS: AFTER BOTH PRACTICES, THE TOTAL AND NET SCORES WERE SIGNIFICANTLY INCREASED, ALTHOUGH THE MAGNITUDE OF CHANGE WAS MORE AFTER CM THAN AFTER SR IN THE NET SCORES (14.5 VERSUS 11.31%). THE NET SCORE CHANGE IN THE CM SESSION WAS SIGNIFICANTLY LARGER THAN THE CHANGE IN THE SR, WHEREAS, THERE WAS NO SIGNIFICANT CHANGE IN THE WRONG CANCELLATION SCORE. AFTER EITHER PRACTICE, THE TOTAL AND NET SCORES WERE SIGNIFICANTLY INCREASED, IRRESPECTIVE OF GENDER AND AGE. CONCLUSIONS: BOTH CM AND SR LED TO IMPROVEMENT IN PERFORMANCE, AS ASSESSED BY SLCT, BUT THE CHANGE CAUSED BY CM WAS LARGER THAN SR.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
10 1357 18 IMMEDIATE EFFECT OF TWO YOGA-BASED RELAXATION TECHNIQUES ON PERFORMANCE IN A LETTER-CANCELLATION TASK. THE PERFORMANCE IN A SIX-LETTER CANCELLATION TASK WAS ASSESSED WITH 69 MALE VOLUNTEERS, AGES 18 TO 48 YEARS, IMMEDIATELY BEFORE AND AFTER TWO YOGA-BASED RELAXATION TECHNIQUES AND A CONTROL SESSION OF EQUAL DURATION. THE TECHNIQUES WERE CYCLIC MEDITATION AND SUPINE REST. CYCLIC MEDITATION CONSISTS OF ALTERNATING CYCLES OF YOGA POSTURES AND SUPINE REST. AFTER BOTH PRACTICES, THE NET SCORES WERE SIGNIFICANTLY HIGHER, ALTHOUGH THE MAGNITUDE OF CHANGE WAS MORE AFTER CYCLIC MEDITATION THAN AFTER SUPINE REST (24.9% VERSUS 13.6%). THERE WAS REDUCTION IN SCORES FOR WRONG CANCELLATIONS AFTER CYCLIC MEDITATION AND NOT AFTER SUPINE REST. THE CONTROL GROUP SHOWED NO CHANGE. THE RESULTS SUGGEST THAT CYCLIC MEDITATION BRINGS ABOUT A GREATER IMPROVEMENT IN PERFORMANCE IN THIS TASK, WHICH REQUIRES SELECTIVE ATTENTION, CONCENTRATION, VISUAL SCANNING ABILITIES, AND A REPETITIVE MOTOR RESPONSE.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
11 2137 14 THE EFFECTS OF ACUTE YOGA ON ANXIETY SYMPTOMS IN RESPONSE TO A CARBON DIOXIDE INHALATION TASK IN WOMEN. PURPOSE: WE INVESTIGATED THE EFFICACY OF YOGA FOR IMPROVING COGNITIVE AND PHYSICAL ANXIETY SYMPTOMS, AND ITS POSSIBLE RESPIRATORY MECHANISM, IN HIGH-ANXIOUS WOMEN. METHODS: EIGHTEEN PARTICIPANTS COMPLETED 40MIN OF GUIDED YOGA AND A LIGHT STRETCHING PROTOCOL IN A RANDOMIZED, COUNTERBALANCED ORDER.THE 7.5%CO2-INHALATION TASK WAS ADMINISTERED BEFORE, IMMEDIATELY AFTER AND 1H AFTER THE EXPERIMENTAL CONDITIONS.STATE ANXIETY AND PANIC WERE MEASURED BEFORE AND AFTER EACH INHALATION TASK.TIDAL VOLUME, VENTILATION AND RESPIRATORY RATE WERE MEASURED DURING EVERY 7.5%CO2-INHALATION TASKS. RESULTS: THERE WAS NO SIGNIFICANT 3-WAY INTERACTION(P>.05).THERE WAS A SIGNIFICANT MAIN EFFECT OF CO2-INHALATION TASK ON PANIC AND RESPIRATORY MEASURES(P<.05).WHEN COLLAPSED OVER INHALATION TASK AND CONDITION, THERE WAS A SMALL REDUCTION IN COGNITIVE ANXIETY FROM BASELINE TO IMMEDIATELY POST AND 1-H POST-CONDITION(P<.05). CONCLUSIONS: THERE APPEARS TO BE AN OVERALL EFFECT OF GENERAL PHYSICAL ACTIVITY FOR ATTENUATING ANXIETY COGNITIONS IRRESPECTIVE OF THE PHYSIOLOGICAL CHANGES, INDICATING POSSIBLE DISSOCIATION BETWEEN THE COGNITIVE AND PHYSICAL SYMPTOMS OF ANXIETY AMONG WOMEN WITH ANXIETY SENSITIVITY.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
12 2511 19 YOGA BREATHING THROUGH A PARTICULAR NOSTRIL IS ASSOCIATED WITH CONTRALATERAL EVENT-RELATED POTENTIAL CHANGES. BACKGROUND: IN EARLIER STUDIES UNINOSTRIL YOGA BREATHING WAS SHOWN TO INFLUENCE THE ACTIVITY OF THE CEREBRAL HEMISPHERES DIFFERENTLY, BASED ON (I) AUDITORY EVOKED POTENTIALS RECORDED FROM BILATERAL SCALP SITES, AND (II) PERFORMANCE IN HEMISPHERE-SPECIFIC TASKS. BUT CHANGE IN P300 (EVENT-RELATED POTENTIAL GENERATED WHEN SUBJECTS ATTEND TO AND DISCRIMINATE BETWEEN STIMULI) FROM BILATERAL SCALP SITES WHEN SUBJECTS WERE PRACTICING UNI- AND ALTERNATE-NOSTRIL BREATHING ARE YET TO BE EXPLORED. AIM: THE PRESENT STUDY WAS DESIGNED TO DETERMINE WHETHER OR NOT IMMEDIATELY AFTER UNINOSTRIL OR ALTERNATE NOSTRIL YOGA BREATHING THERE WOULD BE A CHANGE IN THE ABILITY TO PAY ATTENTION TO A GIVEN STIMULUS. MATERIALS AND METHODS: TWENTY-NINE HEALTHY MALE VOLUNTEERS, WITH AGES BETWEEN 20 AND 45 YEARS WERE RANDOMLY ALLOCATED TO FIVE SESSIONS, VIZ., (I) RIGHT-, (II) LEFT-, (III) ALTERNATE-NOSTRIL YOGA BREATHING, (IV) BREATH AWARENESS AND (V) NO INTERVENTION, EACH FOR 45 MIN ON SEPARATE DAYS. THE P300 EVENT RELATED POTENTIAL WAS RECORDED USING AN AUDITORY ODDBALL PARADIGM FROM SITES ON THE LEFT (C3) AND RIGHT (C4), REFERENCED TO LINKED EARLOBES, BEFORE AND AFTER EACH SESSION. RESULTS: POST-HOC ANALYSIS WITH BONFERRONI ADJUSTMENT SHOWED THAT THE P300 PEAK LATENCY WAS SIGNIFICANTLY LOWER AT C3 COMPARED TO THAT AT C4, FOLLOWING RIGHT NOSTRIL YOGA BREATHING (P<0.05). CONCLUSION: THESE RESULTS SUGGEST THAT RIGHT NOSTRIL YOGA BREATHING FACILITATES THE ACTIVITY OF CONTRALATERAL (LEFT) HEMISPHERE, IN THE PERFORMANCE OF THE P300 TASK.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
13  454 18 CHANGES IN MIDLATENCY AUDITORY EVOKED POTENTIALS FOLLOWING TWO YOGA-BASED RELAXATION TECHNIQUES. PRACTICING MEDITATION WHILE FOCUSING ON A SOUND OR A SYMBOL INFLUENCED MIDLATENCY AUDITORY EVOKED POTENTIALS (MLAEPS). CYCLIC MEDITATION (CM) IS A TECHNIQUE COMBINING YOGA POSTURES WITH MEDITATION WHILE SUPINE, WHICH HAS INFLUENCED THE P300 EVENT-RELATED POTENTIAL. THE EFFECTS OF CM ON MLAEPS HAVE NOT BEEN PREVIOUSLY STUDIED. THE MLAEPS WERE STUDIED BEFORE AND AFTER THE PRACTICE OF CM COMPARED TO AN EQUAL DURATION OF SUPINE REST (SR) IN 47 MALE VOLUNTEERS (GROUP MEAN AGE 26.5 +/- 4.4 YEARS), RECORDED FROM THE VERTEX REFERENCED TO LINKED EARLOBES. THE SESSIONS WERE ONE DAY APART AND SUBJECTS WERE RANDOMLY ASSIGNED TO EACH SESSION. THE PA WAVE PEAK LATENCY AND NB WAVE PEAK LATENCY SIGNIFICANTLY INCREASED FOLLOWING CM COMPARED TO BEFORE CM (REPEATED MEASURES ANOVA, POST-HOC ANALYSIS WITH LEAST SIGNIFICANT DIFFERENCE, P<0.05). THERE WAS A SIGNIFICANT INCREASE IN THE PEAK AMPLITUDE OF THE NB WAVE (P<0.05) COMPARED TO BEFORE CM. POST SR THERE WAS A SIGNIFICANT INCREASE IN THE PEAK LATENCY OF THE NA WAVE (P<0.05) COMPARED TO BEFORE SR. IN CONCLUSION FOLLOWING CM THE LATENCIES OF NEURAL GENERATORS CORRESPONDING TO CORTICAL AREAS IS PROLONGED, WHEREAS FOLLOWING SR A SIMILAR CHANGE OCCURS AT MESENCEPHALIC-DIENCEPHALIC LEVELS.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
14  768 17 EFFECT OF TWO YOGA-BASED RELAXATION TECHNIQUES ON MEMORY SCORES AND STATE ANXIETY. BACKGROUND: A YOGA PRACTICE INVOLVING CYCLES OF YOGA POSTURES AND SUPINE REST (CALLED CYCLIC MEDITATION) WAS PREVIOUSLY SHOWN TO IMPROVE PERFORMANCE IN ATTENTION TASKS MORE THAN RELAXATION IN THE CORPSE POSTURE (SHAVASANA). THIS WAS ASCRIBED TO REDUCED ANXIETY, THOUGH THIS WAS NOT ASSESSED. METHODS: IN FIFTY-SEVEN MALE VOLUNTEERS (GROUP AVERAGE AGE +/- S.D., 26.6 +/- 4.5 YEARS) THE IMMEDIATE EFFECT OF TWO YOGA RELAXATION TECHNIQUES WAS STUDIED ON MEMORY AND STATE ANXIETY. ALL PARTICIPANTS WERE ASSESSED BEFORE AND AFTER (I) CYCLIC MEDITATION (CM) PRACTICED FOR 22:30 MINUTES ON ONE DAY AND (II) AN EQUAL DURATION OF SUPINE REST (SR) OR THE CORPSE POSTURE (SHAVASANA), ON ANOTHER DAY. SECTIONS OF THE WECHSLER MEMORY SCALE (WMS) WERE USED TO ASSESS; (I) ATTENTION AND CONCENTRATION (DIGIT SPAN FORWARD AND BACKWARD), AND (II) ASSOCIATE LEARNING. STATE ANXIETY WAS ASSESSED USING SPIELBERGER'S STATE-TRAIT ANXIETY INVENTORY (STAI). RESULTS: THERE WAS A SIGNIFICANT IMPROVEMENT IN THE SCORES OF ALL SECTIONS OF THE WMS STUDIED AFTER BOTH CM AND SR, BUT, THE MAGNITUDE OF CHANGE WAS MORE AFTER CM COMPARED TO AFTER SR. THE STATE ANXIETY SCORES DECREASED AFTER BOTH CM AND SR, WITH A GREATER MAGNITUDE OF DECREASE AFTER CM. THERE WAS NO CORRELATION BETWEEN PERCENTAGE CHANGE IN MEMORY SCORES AND STATE ANXIETY FOR EITHER SESSION. CONCLUSION: A CYCLICAL COMBINATION OF YOGA POSTURES AND SUPINE REST IN CM IMPROVED MEMORY SCORES IMMEDIATELY AFTER THE PRACTICE AND DECREASED STATE ANXIETY MORE THAN REST IN A CLASSICAL YOGA RELAXATION POSTURE (SHAVASANA).	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
15 2362 20 VOLITIONAL YOGA BREATHING INFLUENCES ATTENTION AND ANXIETY: AN EXPLORATORY RANDOMIZED CROSSOVER STUDY. BACKGROUND: PREVIOUS STUDIES ASSESSED YOGA BREATHING PRACTICES INDIVIDUALLY. THIS EXPLORATORY, RANDOMIZED CROSSOVER STUDY ASSESSED ATTENTION AND ANXIETY FOLLOWING FOUR YOGA BREATHING PRACTICES, BREATH AWARENESS, AND QUIET SEATED REST. MATERIALS AND METHODS: THIRTY-EIGHT MALE VOLUNTEERS BETWEEN 20 AND 37 YEARS (GROUP MEAN AGE +/- SD; 24.08 +/- 4.01 YEARS) WERE ASSESSED IN SIX SESSIONS IN RANDOM ORDER (WWW.RANDOMIZER.ORG) ON SEPARATE DAYS. THE SESSIONS WERE: (I) ALTERNATE NOSTRIL YOGA BREATHING, (II) BELLOWS YOGA BREATHING, (III) BUMBLEBEE YOGA BREATHING, (IV) HIGH-FREQUENCY YOGA BREATHING, (V) BREATH AWARENESS, AND (VI) QUIET SEATED REST. THE SESSIONS WERE FOR 18 MIN EACH. SIX LETTER CANCELLATION TEST (SLCT) AND SPIELBERGER'S STATE TRAIT ANXIETY INVENTORY-STATE (STAI-S) WERE ADMINISTERED PRE AND POST EACH SESSION. DATA ANALYSIS USED GENERAL LINEAR MIXED MODEL ANALYSIS, WITH FIXED EFFECT OF STATES (PRE AND POST) AND SESSIONS. RESULTS: A SIGNIFICANT MAIN EFFECT OF STATES WAS OBSERVED ON TOTAL ATTEMPTED (F1,407 = 5.374, P = 0.021) AND NET ATTEMPTED SCORES (F1,407 = 6.178, P = 0.013) OF THE SLCT, WITH A SIGNIFICANT INCREASE IN SCORES FOLLOWING HIGH-FREQUENCY YOGA BREATHING (PADJ = 0.031 FOR TOTAL ATTEMPTED SCORES; PADJ = 0.029 FOR NET ATTEMPTED SCORES). ALSO, A SIGNIFICANT MAIN EFFECT OF STATES ON STAI-S SCORES WAS OBSERVED (F1,407 = 33.979, P < 0.001), WITH A SIGNIFICANT DECREASE IN SCORES FOLLOWING ALTERNATE NOSTRIL YOGA BREATHING (PADJ = 0.001), BELLOWS YOGA BREATHING (PADJ = 0.008), BUMBLEBEE YOGA BREATHING (PADJ = 0.002), AND HIGH-FREQUENCY YOGA BREATHING (PADJ = 0.042) COMPARED TO THE CORRESPONDING PRE STATE. THERE WAS A SIGNIFICANT MAIN EFFECT OF SESSIONS (F5,407 = 3.043, P = 0.010) ON STAI-S SCORES, WITH SCORES POST ALTERNATE NOSTRIL YOGA BREATHING SIGNIFICANTLY LOWER THAN POST BREATH AWARENESS (PADJ = 0.037). CONCLUSION: FOLLOWING HIGH-FREQUENCY YOGA BREATHING SUSTAINED ATTENTION WAS BETTER THAN BEFORE WHILE STATE ANXIETY DECREASED IN POST-PRE COMPARISONS OF ALTERNATE NOSTRIL YOGA BREATHING, BELLOWS YOGA BREATHING, BUMBLEBEE YOGA BREATHING, AND HIGH-FREQUENCY YOGA BREATHING. THE DIFFERENCES BETWEEN BREATHING PRACTICES MAY BE DUE TO DIFFERENCES IN DEGREE OF VOLITIONAL REGULATION OF BREATHING AND IN THE BREATH PATTERNS MODIFIED VOLITIONALLY. THE GENERALIZABILITY OF THE FINDINGS WAS LIMITED BY INCLUDING AN ALL MALE, YOGA EXPERIENCED SAMPLE. FUTURE RESEARCH SHOULD INCLUDE PARTICIPANTS OF BOTH GENDERS AND COULD INCLUDE DIFFERENT LEVELS OF YOGA EXPERIENCE, WITH ASSESSMENTS INCLUDING OBJECTIVE MEASURES OF ATTENTION AND ANXIETY.	2022	

16 1599 20 MEDITATIVE STATES BASED ON YOGA TEXTS AND THEIR EFFECTS ON PERFORMANCE OF A LETTER-CANCELLATION TASK. PERFORMANCE IN A SIX-LETTER CANCELLATION TASK WAS STUDIED IN 35 MALE EXPERIENCED MEDITATORS WITH EXPERIENCE RANGING FROM 6 TO 12 MONTHS. EACH PARTICIPANT WAS STUDIED IN FOUR SESSIONS, TWO MEDITATION AND TWO CONTROL SESSIONS. THE CONTROL SESSIONS WERE (I) CANCALATA OR NONTARGETED THINKING AND (II) EKAGRATA OR FOCUSING ON A SINGLE TOPIC, IN THIS CASE, MEDITATION. THE MEDITATION SESSIONS WERE (I) DHARANA OR FOCUSING ON THE SYMBOL "OM" AND (II) DHYANA OR AN EFFORTLESS SINGLE-THOUGHT (OF OM) STATE. EKAGRATA AND DHARANA DIFFER IN THAT THE FORMER INVOLVES FOCUSING WITH MULTIPLE THOUGHTS WHEREAS THE LATTER INVOLVES FOCUSING WITH A SINGLE THOUGHT, I.E., THE SIGNIFICANCE OF OM. THE NET SCORES ON THE SIX-LETTER CANCELLATION TASK WERE SIGNIFICANTLY HIGHER AFTER A SESSION OF DHARANA AND LOWER AFTER THE CANCALATA SESSION, WHILE THERE WAS NO SIGNIFICANT CHANGE AFTER EKAGRATA AND DHYANA SESSIONS. FOCUSING ON THE SYMBOL OM IN DHARANA MAY FAVORABLY INFLUENCE SELECTIVE ATTENTION, CONCENTRATION, VISUAL SCANNING ABILITIES, AND A REPETITIVE MOTOR RESPONSE COMPARED TO OTHER SESSIONS.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
17  690 19 EFFECT OF COMBINED YOGA AND TRANSCRANIAL DIRECT CURRENT STIMULATION INTERVENTION ON WORKING MEMORY AND MINDFULNESS. TRANSCRANIAL DIRECT STIMULATION, A NON-INVASIVE NEUROSTIMULATION TECHNIQUE FOR MODULATING CORTICAL EXCITABILITY, AND YOGA HAVE BOTH RESPECTIVELY BEEN SHOWN TO POSITIVELY AFFECT COGNITION. WHILE PRELIMINARY RESEARCH HAS SHOWN THAT COMBINED TRANSCRANIAL DIRECT STIMULATION AND MEDITATION MAY HAVE SYNERGISTIC EFFECTS ON MOOD AND COGNITION, THIS WAS THE FIRST STUDY TO EXPLORE THE COMBINATION OF TRANSCRANIAL DIRECT STIMULATION AND YOGA. TWENTY-TWO HEALTHY VOLUNTEERS WITH A REGULAR YOGA PRACTICE WERE RANDOMIZED TO RECEIVE EITHER ACTIVE TRANSCRANIAL DIRECT STIMULATION (ANODAL LEFT, CATHODAL RIGHT DORSOLATERAL PREFRONTAL CORTEX) FOLLOWED BY YOGA INTERVENTION OR SHAM TRANSCRANIAL DIRECT STIMULATION FOLLOWED BY YOGA INTERVENTION A DOUBLE-BLIND, CROSS-OVER DESIGN OVER TWO SEPARATE INTERVENTION DAYS. OUTCOME MEASURES INCLUDED WORKING MEMORY PERFORMANCE, MEASURED WITH THE N-BACK TASK AND MINDFULNESS STATE, MEASURED WITH THE TORONTO MINDFULNESS SCALE, AND WERE CONDUCTED OFFLINE, WITH PRE-POST ASSESSMENTS. TWENTY PARTICIPANTS COMPLETED BOTH DAYS OF THE INTERVENTION. ACTIVE TRANSCRANIAL DIRECT STIMULATION DID NOT HAVE A SIGNIFICANT EFFECT ON WORKING MEMORY OR LEVELS OF MINDFULNESS. THERE WAS A SIGNIFICANT PLACEBO EFFECT, WITH BETTER PERFORMANCE ON DAY 1 OF THE INTERVENTION, IRRESPECTIVE OF WHETHER PARTICIPANTS RECEIVED ACTIVE OR SHAM TRANSCRANIAL DIRECT STIMULATION. THERE WAS NO SIGNIFICANT DIFFERENCE BETWEEN ACTIVE VERSUS SHAM TRANSCRANIAL DIRECT STIMULATION CONCERNING WORKING MEMORY PERFORMANCE AND MINDFULNESS, WHICH MAY BE ACCOUNTED BY THE SMALL SAMPLE SIZE, THE TRANSIENT NATURE OF THE INTERVENTION, THE FACT THAT YOGA AND TRANSCRANIAL DIRECT STIMULATION CONCERNING WERE NOT CONDUCTED SIMULTANEOUSLY, AND THE SPECIFIC SITE OF STIMULATION.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
18  868 19 EFFECT OF YOGA RELAXATION TECHNIQUES ON PERFORMANCE OF DIGIT-LETTER SUBSTITUTION TASK BY TEENAGERS. BACKGROUND/AIMS: MEMORY AND SELECTIVE ATTENTION ARE IMPORTANT SKILLS FOR ACADEMIC AND PROFESSIONAL PERFORMANCE. TECHNIQUES TO IMPROVE THESE SKILLS ARE NOT TAUGHT EITHER IN EDUCATION OR COMPANY TRAINING COURSES. ANY SYSTEM WHICH CAN SYSTEMATICALLY IMPROVE THESE SKILLS WILL BE OF VALUE IN SCHOOLS, UNIVERSITIES, AND WORKPLACES. AIMS: TO INVESTIGATE POSSIBLE IMPROVEMENTS IN MEMORY AND SELECTIVE ATTENTION, AS MEASURED BY THE DIGIT-LETTER SUBSTITUTION TASK (DLST), DUE TO PRACTICE OF CYCLIC MEDITATION (CM), A YOGA RELAXATION TECHNIQUE, AS COMPARED TO SUPINE REST (SR). MATERIALS AND METHODS: SUBJECTS CONSISTED OF 253 SCHOOL STUDENTS, 156 BOYS, 97 GIRLS, IN THE AGE RANGE 13-16 YEARS, WHO WERE ATTENDING A 10-DAY YOGA TRAINING COURSE DURING SUMMER VACATION. THE SELECTED SUBJECTS HAD ENGLISH AS THEIR MEDIUM OF INSTRUCTION IN SCHOOL AND THEY ACTED AS THEIR OWN CONTROLS. THEY WERE ALLOCATED TO TWO GROUPS, AND TESTED ON THE DLST, IMMEDIATELY BEFORE AND AFTER 22.5 MINUTES PRACTICE OF CM ON ONE DAY, AND IMMEDIATELY BEFORE AND AFTER AN EQUAL PERIOD OF SR ON THE OTHER DAY. THE FIRST GROUP PERFORMED CM ON DAY 9 AND SR ON DAY 10. FOR THE SECOND GROUP, THE ORDER WAS REVERSED. RESULTS: WITHIN EACH GROUP PRE-POST TEST DIFFERENCES WERE SIGNIFICANT FOR BOTH THE RELAXATION TECHNIQUES. THE MAGNITUDE OF NET SCORE IMPROVEMENT WAS GREATER AFTER SR (7.85%) COMPARED TO CM (3.95%). SIGNIFICANCE LEVELS WERE P < 0.4 X 10(-9)FOR SR AND P < 0.1 X 10(-3) FOR CM. THE NUMBER OF WRONG ATTEMPTS ALSO INCREASED SIGNIFICANTLY ON BOTH INTERVENTIONS, EVEN AFTER REMOVING TWO OUTLIER DATA POINTS ON DAY 1 IN THE SR GROUP. CONCLUSIONS: BOTH CM AND SR LEAD TO IMPROVEMENT IN PERFORMANCE ON THE DLST. HOWEVER, THESE RELAXATION TECHNIQUES LEAD TO MORE WRONG CANCELLATION ERRORS.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
19 2510 21 YOGA BREATHING THROUGH A PARTICULAR NOSTRIL INCREASES SPATIAL MEMORY SCORES WITHOUT LATERALIZED EFFECTS. UNINOSTRIL BREATHING FACILITATES THE PERFORMANCE ON SPATIAL AND VERBAL COGNITIVE TASKS, SAID TO BE RIGHT AND LEFT BRAIN FUNCTIONS, RESPECTIVELY. SINCE HEMISPHERIC MEMORY FUNCTIONS ARE ALSO KNOWN TO BE LATERALIZED, THE PRESENT STUDY ASSESSED THE EFFECTS OF UNINOSTRIL BREATHING ON THE PERFORMANCE IN VERBAL AND SPATIAL MEMORY TESTS. SCHOOL CHILDREN (N = 108 WHOSE AGES RANGED FROM 10 TO 17 YEARS) WERE RANDOMLY ASSIGNED TO FOUR GROUPS. EACH GROUP PRACTICED A SPECIFIC YOGA BREATHING TECHNIQUE: (I) RIGHT NOSTRIL BREATHING, (II) LEFT NOSTRIL BREATHING, (III) ALTERNATE NOSTRIL BREATHING, OR (IV) BREATH AWARENESS WITHOUT MANIPULATION OF NOSTRILS. THESE TECHNIQUES WERE PRACTICED FOR 10 DAYS. VERBAL AND SPATIAL MEMORY WAS ASSESSED INITIALLY AND AFTER 10 DAYS. AN AGE-MATCHED CONTROL GROUP OF 27 WERE SIMILARLY ASSESSED. ALL 4 TRAINED GROUPS SHOWED A SIGNIFICANT INCREASE IN SPATIAL TEST SCORES AT RETEST, BUT THE CONTROL GROUP SHOWED NO CHANGE. AVERAGE INCREASE IN SPATIAL MEMORY SCORES FOR THE TRAINED GROUPS WAS 84%. IT APPEARS YOGA BREATHING INCREASES SPATIAL RATHER THAN VERBAL SCORES, WITHOUT A LATERALIZED EFFECT.	1997	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
20 2241 15 THE INFLUENCE OF HATHA YOGA AS AN ADD-ON TREATMENT IN MAJOR DEPRESSION ON HYPOTHALAMIC-PITUITARY-ADRENAL-AXIS ACTIVITY: A RANDOMIZED TRIAL. OBJECTIVES: THE IMPACT OF HATHA YOGA AS ADD-ON TREATMENT TO QUETIAPINE FUMARATE EXTENDED RELEASE (QXR) OR ESCITALOPRAM (ESC) IN DEPRESSED PATIENTS ON HYPOTHALAMIC-PITUITARY-ADRENAL (HPA) AXIS ACTIVITY WAS ASSESSED. METHODS: 60 INPATIENTS SUFFERING FROM MAJOR DEPRESSIVE DISORDER (MDD) ACCORDING TO DSM-IV WERE RANDOMIZED FOR A 5 WEEK TREATMENT WITH YOGA OR NOT (CONTROL GROUP) AND WITH EITHER QXR (300 MG/DAY) OR ESC (10 MG/DAY). SERIAL DEXAMETHASONE/CORTICOTROPIN RELEASING HORMONE (DEX/CRH) TESTS WERE PERFORMED TO ASSESS HPA AXIS FUNCTION. THE HAMILTON DEPRESSION RATING SCALE (21-HAMD) WAS USED WEEKLY. RESULTS: A MORE PRONOUNCED DOWN REGULATION OF THE HPA AXIS ACTIVITY DUE TO YOGA COULD NOT BE DETECTED. THE STEPWISE LONG TERM CORTISOL REDUCTION WAS SEEN IN BOTH MEDICATION GROUPS, IRRESPECTIVELY OF YOGA ADD-ON TREATMENT. IN ADDITION, CORTISOL IMPROVERS IN WEEK 1 OF THERAPY (REDUCTION IN CORTISOL PEAK VALUE WITHIN THE DEX/CRH TEST) REACHED SIGNIFICANT GREATER AMELIORATION OF DEPRESSIVE SYMPTOMS AFTER 5 WEEKS. CONCLUSIONS: OUR RESULTS SUGGEST THAT ANTIDEPRESSANT AGENTS DOWN REGULATE HPA AXIS FUNCTION TO A GREATER EXTENT THAN ADDITIONAL HATHA YOGA TREATMENT. MOREOVER, AN EARLY REDUCTION OF HPA SYSTEM HYPERACTIVITY AFTER ONE WEEK OF PHARMACOLOGICAL TREATMENT SEEMS TO RAISE THE POSSIBILITY OF A FAVORABLE TREATMENT RESPONSE.	2014