1 1396 85 IMPACT OF YOGA IN A CASE OF VOCAL CORD DYSFUNCTION WITH DYSAUTONOMIA. A 23-YEAR-OLD FEMALE WITH A PAST MEDICAL HISTORY OF GASTROESOPHAGEAL REFLUX DISEASE PRESENTED WITH SHORTNESS OF BREATH INDUCED BY EXERCISE AND CERTAIN ODORS. SHE REPORTED THE SYMPTOMS OF AUTONOMIC DYSFUNCTION INCLUDING FATIGUE, CHEST PAIN, LIGHTHEADEDNESS, HEADACHES, NUMBNESS/TINGLING IN THE ARMS AND LEGS, AND EXERCISE INTOLERANCE. VITAL SIGNS WERE SIGNIFICANT FOR ORTHOSTATIC INTOLERANCE. VOLUME FLOW LOOP IN THE PULMONARY FUNCTION TESTS SHOWED A FLATTENING OF THE INSPIRATORY PORTION CHARACTERISTIC OF VOCAL CORD DYSFUNCTION. LARYNGOSCOPY SHOWED DYSKINESIA OF THE LEFT VOCAL CORD, ESPECIALLY AFTER EXERCISE. MULTIFACTORIAL APPROACH WAS USED INCLUDING INCREASED FLUID INTAKE AND BREATHING EXERCISES. AFTER 6 WEEKS OF BREATHING AND ISOMETRIC EXERCISES, THE PATIENT REPORTED IMPROVEMENT IN DYSPNEA AFTER EXERCISE. THIS CASE REPORT DEMONSTRATES THE THERAPEUTIC ROLE OF BREATHING AND ISOMETRIC EXERCISES IN THE MANAGEMENT OF VOCAL CORD AND AUTONOMIC DYSFUNCTION.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
2 2759 13 YOGA PRACTITIONERS EXHIBIT HIGHER PARASYMPATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY AND BETTER ADAPTABILITY TO 40 MM HG LOWER-BODY NEGATIVE PRESSURE. YOGA HAS BEEN SHOWN TO IMPROVE AUTONOMIC CONDITIONING IN HUMANS, AS EVIDENCED BY THE ENHANCEMENT OF PARASYM-PATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY. THEREFORE, WE HYPOTHESIZED THAT THE EXPERIENCE OF YOGA MAY RESULT IN ADAPTATION TO ACUTE HEMODYNAMIC CHANGES. TO DECIPHER THE LONG-TERM EFFECTS OF YOGA ON CARDIOVASCULAR VARIABILITY, YOGA PRACTITIONERS WERE COMPARED TO YOGA-NAIVE SUBJECTS DURING EXPOSURE TO -40 MM HG LOWER-BODY NEGATIVE PRESSURE (LBNP). A COMPARATIVE STUDY WAS CONDUCTED ON 40 YOGANAIVE SUBJECTS AND 40 YOGA PRACTITIONERS WITH AN AVERAGE AGE OF 31.08 +/- 7.31 YEARS AND 29.93 +/- 7.57 YEARS, RESPECTIVELY. HEART RATE VARIABILITY, BLOOD PRESSURE VARIABILITY, BAROREFLEX SENSITIVITY, AND CORRELATION BETWEEN SYSTOLIC BLOOD PRESSURE AND RR INTERVAL WERE EVALUATED AT REST AND DURING LBNP. IN YOGA PRACTITIONERS, THE HEART RATE WAS LOWER IN SUPINE REST (P = 0.011) AND DURING LBNP (P = 0.043); THE PNN50 MEASURE OF HEART RATE VARIABILITY WAS HIGHER IN SUPINE REST (P = 0.011) AND DURING LBNP (P = 0.034). THE YOGA PRACTITIONERS' STANDARD DEVIATION OF SUCCESSIVE BEAT-TO-BEAT BLOOD PRESSURE INTERVALS OF SYSTOLIC BLOOD PRESSURE VARIABILITY WAS LOWER IN SUPINE REST (P = 0.034) AND DURING LBNP (P = 0.007), WITH HIGHER SEQUENCE BAROREFLEX SENSITIVITY (P = 0.019) AND ~ HIGH-FREQUENCY BAROREFLEX SENSITIVITY. MEAN SYSTOLIC BLOOD PRESSURE AND RR INTERVAL WERE INVERSELY CORRELATED IN THE YOGA GROUP (R = -0.317, P = 0.049). THE YOGA PRACTITIONERS EXHIBITED HIGHER PARASYMPATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY WITH LOWER SYSTOLIC BLOOD PRESSURE VARIABILITY, INDICATING BETTER ADAPTABILITY TO LBNP COMPARED TO THE YOGA-NAIVE GROUP. OUR FINDINGS INDICATE THAT THE YOGA MODULE WAS HELPFUL IN CONDITIONS OF HYPOVOLEMIA IN HEALTHY SUBJECTS; IT IS PROPOSED TO BE BENEFICIAL IN CLINICAL CONDITIONS ASSOCIATED WITH SYMPATHETIC DOMINANCE, IMPAIRED BARORE-FLEX SENSITIVITY, AND ORTHOSTATIC INTOLERANCE.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
3 1045 18 EFFECTS OF YOGA INTERVENTIONS PRACTISED IN HEATED AND THERMONEUTRAL CONDITIONS ON ENDOTHELIUM-DEPENDENT VASODILATATION: THE BIKRAM YOGA HEART STUDY. NEW FINDINGS: WHAT IS THE CENTRAL QUESTION OF THIS STUDY? DOES THE HEATED PRACTICE ENVIRONMENT ENHANCE THE EFFECTS OF BIKRAM YOGA ON ENDOTHELIUM-DEPENDENT VASODILATATION IN HEALTHY, MIDDLE-AGED ADULTS? WHAT IS THE MAIN FINDING AND ITS IMPORTANCE? THE PRIMARY FINDING FROM THIS INVESTIGATION IS THAT THE HATHA YOGA POSTURES IN THE BIKRAM YOGA SERIES PRODUCE SIMILAR ENHANCEMENTS IN ENDOTHELIUM-DEPENDENT VASODILATATION IN HEALTHY, MIDDLE-AGED ADULTS REGARDLESS OF ENVIRONMENTAL TEMPERATURE. THESE FINDINGS HIGHLIGHT THE EFFICACY OF YOGA POSTURES IN PRODUCING IMPROVEMENTS IN VASCULAR HEALTH AND DOWNPLAY THE NECESSITY OF THE HEATED PRACTICE ENVIRONMENT IN INDUCING VASCULAR ADAPTATIONS. ABSTRACT: WE HAVE PREVIOUSLY DOCUMENTED IMPROVEMENTS IN ENDOTHELIUM-DEPENDENT VASODILATATION WITH A BIKRAM (HOT) YOGA INTERVENTION IN MIDDLE-AGED ADULTS. AT PRESENT, THE EFFECT OF ENVIRONMENTAL TEMPERATURE IN HOT YOGA ON ENDOTHELIAL FUNCTION IS UNKNOWN. THE PURPOSE OF THIS INVESTIGATION WAS TO DETERMINE THE EFFECTS OF BIKRAM YOGA INTERVENTIONS PERFORMED IN HEATED OR THERMONEUTRAL CONDITIONS ON ENDOTHELIUM-DEPENDENT VASODILATATION. FIFTY-TWO SEDENTARY BUT APPARENTLY HEALTHY ADULTS AGED 40-60 YEARS WERE RANDOMLY ASSIGNED TO ONE OF THREE GROUPS: BIKRAM YOGA PRACTISED AT 40.5 DEGREES C (N = 19), BIKRAM YOGA PRACTISED AT 23 DEGREES C (N = 14) OR SEDENTARY TIME CONTROL (N = 19). THE YOGA INTERVENTIONS CONSISTED OF 90 MIN BIKRAM YOGA CLASSES THREE TIMES A WEEK FOR 12 WEEKS. ENDOTHELIUM-DEPENDENT VASODILATATION WAS MEASURED NON-INVASIVELY USING BRACHIAL ARTERY FLOW-MEDIATED DILATATION (FMD). BODY FAT PERCENTAGE DETERMINED VIA DUAL-ENERGY X-RAY ABSORPTIOMETRY WAS SIGNIFICANTLY LOWER IN THE HOT YOGA GROUP AFTER THE INTERVENTION THAN IN THE THERMONEUTRAL YOGA AND CONTROL CONDITIONS. BRACHIAL ARTERY FMD INCREASED (P < 0.05) IN THE THERMONEUTRAL YOGA GROUP AND TENDED TO INCREASE IN THE HOT YOGA GROUP (P = 0.056). NO CHANGES OCCURRED IN THE CONTROL GROUP. THERE WERE NO SIGNIFICANT DIFFERENCES IN FMD CHANGE SCORES BETWEEN GROUPS. WE CONCLUDE THAT BIKRAM YOGA PRACTISED IN THERMONEUTRAL CONDITIONS IMPROVED ENDOTHELIUM-DEPENDENT VASODILATATION IN HEALTHY, MIDDLE-AGED ADULTS. THESE NEW FINDINGS HIGHLIGHT THE EFFECTIVENESS OF HATHA YOGA POSTURES ALONE, IN THE ABSENCE OF A HEATED PRACTICE ENVIRONMENT, IN IMPROVING VASCULAR HEALTH AND ARE OF CLINICAL SIGNIFICANCE GIVEN THE INCREASED PROPENSITY FOR HEAT INTOLERANCE IN AGEING ADULTS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
4  370 16 AUTONOMIC TONE AND BAROREFLEX SENSITIVITY DURING 70 DEGREES HEAD-UP TILT IN YOGA PRACTITIONERS. INTRODUCTION: THE INTERVENTION OF YOGA WAS SHOWN TO IMPROVE THE AUTONOMIC CONDITIONING IN HUMANS EVIDENT FROM THE ENHANCEMENT OF PARASYMPATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY (BRS). FROM THE DOCUMENTED HEALTH BENEFITS OF YOGA, WE HYPOTHESIZED THAT THE EXPERIENCE OF YOGA MAY RESULT IN ADAPTATION TO THE ORTHOSTATIC STRESS DUE TO ENHANCED BRS. AIM: TO DECIPHER THE EFFECTS OF YOGA IN THE MODULATION OF AUTONOMIC FUNCTION DURING ORTHOSTATIC CHALLENGE. MATERIALS AND METHODS: THIS WAS A COMPARATIVE STUDY DESIGN CONDUCTED IN AUTONOMIC FUNCTION TEST LAB, OF THE DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA. HEART RATE VARIABILITY (HRV), BLOOD PRESSURE VARIABILITY, AND BRS WERE ANALYZED ON FORTY NAIVE TO YOGA (NY) SUBJECTS AND FORTY YOGA PRACTITIONERS WITH AN AVERAGE AGE OF 31.08 +/- 7.31 YEARS AND 29.93 +/- 7.57 YEARS, RESPECTIVELY. ALL PARTICIPANTS WERE HEALTHY. SEVENTY DEGREES HEAD UP TILT (HUT) WAS USED AS AN INTERVENTION TO EVALUATE THE CARDIOVASCULAR VARIABILITY DURING ORTHOSTATIC CHALLENGE. RESULTS: DURING HUT, THE R-R INTERVAL (P = 0.042), ROOT MEAN SQUARE OF SUCCESIVE R-R INTERVAL DIFFERENCES (RMSSD) (P = 0.039), STANDARD DEVIATION OF INSTANTANEOUS BEAT-TO-BEAT R-R INTERVAL VARIABILITY (SD1) (P = 0.039) OF HRV, AND SEQUENCE BRS (P = 0.017) AND ALPHA LOW FREQUENCY OF SPECTRAL BRS (P = 0.002) WERE HIGHER IN THE YOGA GROUP. THE DELTA DECREASE IN RRI (P = 0.033) AND BRS (P < 0.01) WAS HIGHER IN THE YOGA GROUP THAN THE NY GROUP. CONCLUSION: THE EFFERENT VAGAL ACTIVITY AND BRS WERE HIGHER IN YOGA PRACTITIONERS. THE DELTA CHANGE (DECREASE) IN PARASYMPATHETIC ACTIVITY AND BRS WAS HIGHER, WITH RELATIVELY STABLE SYSTOLIC BLOOD PRESSURE INDICATING AN ADAPTIVE RESPONSE TO ORTHOSTATIC CHALLENGE BY THE YOGA PRACTITIONERS COMPARED TO THE NY GROUP.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
5  993  9 EFFECTS OF HEATED AND THERMONEUTRAL YOGA INTERVENTIONS ON ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS. THE STUDY INVESTIGATED THE EFFICACY OF 12 WEEKS OF HEATED AND THERMONEUTRAL BIKRAM YOGA IN REDUCING ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS. FIFTY-FOUR SEDENTARY ADULTS (AGES 40-60 YEARS) COMPLETED 12 WEEKS OF YOGA AT 40.5 DEGREES C (N = 21), YOGA AT 23 DEGREES C (N = 14) OR TIME CONTROL (N = 19). BRACHIAL-ANKLE PULSE WAVE VELOCITY (PWV) WAS NOT SIGNIFICANTLY ALTERED BY HOT OR THERMONEUTRAL YOGA INTERVENTIONS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
6  758 15 EFFECT OF SLOW BREATHING ON AUTONOMIC TONE & BAROREFLEX SENSITIVITY IN YOGA PRACTITIONERS. BACKGROUND & OBJECTIVES: SLOW BREATHING INCREASES PARASYMPATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY (BRS) IN HEALTHY INDIVIDUALS, ALSO SIMILARLY OBSERVED IN YOGA PRACTITIONERS. PRANAYAMA WHICH IS AN IMPORTANT COMPONENT OF YOGA WHEN PRACTICED AT A SLOW PACE WAS AT A RESPIRATORY FREQUENCY OF AROUND 0.1 HZ (6 BREATHS/MIN). THEREFORE, IT WAS HYPOTHESIZED THAT YOGA PRACTITIONERS MIGHT HAVE ADAPTED TO SLOW BREATHING. THIS STUDY WAS AIMED TO DECIPHER THE ROLE OF YOGA ON CARDIOVASCULAR VARIABILITY DURING SLOW BREATHING (0.1 HZ) IN YOGA PRACTITIONERS. METHODS: A CROSS-SECTIONAL STUDY WAS UNDERTAKEN IN NAIVE-TO-YOGA INDIVIDUALS (N=40) AND YOGA PRACTITIONERS (N=40) WITH AN AVERAGE AGE OF 31.08 +/- 7.31 AND 29.93 +/- 7.57 YR, RESPECTIVELY. THE ANALYSIS OF HEART RATE VARIABILITY, BLOOD PRESSURE VARIABILITY (BPV) AND BRS DURING SPONTANEOUS AND SLOW BREATHING WAS COMPARED BETWEEN THE TWO GROUPS. RESULTS: DURING SLOW BREATHING, THE HEART RATE (P<0.01) WAS LOWER, RESPIRATORY RATE INTERVAL (P<0.05) AND PNN50 PER CENT (P=0.01) WERE HIGHER, MEAN SYSTOLIC BP (SBP) (P<0.05) AND SDSD (STANDARD DEVIATION OF SUCCESSIVE BEAT TO BEAT SYSTOLIC BLOOD PRESSURE DIFFERENCES) (P<0.01) OF SBP VARIABILITY WERE LOWER WITH SEQUENCE BRS (P<0.001) AND ALPHA LOW FREQUENCY (P<0.01) AND ALPHA HIGH FREQUENCY (P<0.001) OF SPECTRAL BRS WERE HIGHER IN YOGA PRACTITIONERS. INTERPRETATION & CONCLUSIONS: THE PRESENT STUDY INDICATED HIGHER PARASYMPATHETIC ACTIVITY AND BRS WITH LOWER SBP VARIABILITY AT REST AND DURING SLOW BREATHING IN YOGA PRACTITIONERS COMPARED TO NAIVE GROUP. FINDINGS INDICATE THAT THE SHORT-TERM PRACTICE OF SLOW BREATHING COMPLEMENTS THE AUGMENTED PARASYMPATHETIC ACTIVITY AND BRS IN THE YOGA GROUP.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
7 2065 22 THE CARDIOVASCULAR VARIABILITY DURING TRANSIENT 6 DEGREES HEAD DOWN TILT AND SLOW BREATHING IN YOGA EXPERIENCED HEALTHY INDIVIDUALS. OBJECTIVE: THE INTERVENTION OF YOGA HAS BEEN SHOWN TO IMPROVE AUTONOMIC CONDITIONING IN HUMANS AND BETTER ADAPTABILITY TO ORTHOSTATIC CHALLENGES. SIMILARLY, SLOW BREATHING AT 0.1 HZ AKIN TO PRANAYAMA ALSO INCREASES BAROREFLEX SENSITIVITY (BRS). HENCE, WE INTENDED TO INVESTIGATE WHETHER YOGA PRACTITIONERS HAVE DIFFERENT AUTONOMIC RESPONSES AT REST,DURING SLOW DEEP BREATHINGAS WELL AS DURING 6 DEGREES HEAD DOWN TILT (HDT) COMPARED TO NAIVE GROUP INDIVIDUALS. AIM: THE AIM OF THE STUDY WAS TO EVALUATE THE ACUTE EFFECTS OF SLOW BREATHING ON CARDIOVASCULAR VARIABILITY DURING HDT IN YOGA PRACTITIONERS COMPARED TO YOGA-NAIVE INDIVIDUALS. SETTINGS AND DESIGN: THIS WAS A COMPARATIVE STUDY WITH REPEATED MEASURES DESIGN CONDUCTED IN AUTONOMIC FUNCTION TEST LAB OF THE DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA. MATERIALS AND METHODS: TIME DOMAIN AND FREQUENCY DOMAIN PARAMETERS OF HEART RATE VARIABILITY, BLOOD PRESSURE VARIABILITY (BPV), AND BRS WERE EVALUATED DURING 6 DEGREES HDT AND SLOW BREATHING AT 0.1 HZ ON FORTY YOGA-NAIVE INDIVIDUALS AND FORTY YOGA PRACTITIONERS WITH AN AVERAGE AGE OF 31.08 +/- 7.31 YEARS AND 29.93 +/- 7.57 YEARS, RESPECTIVELY. ALL OF THE PARTICIPANTS WERE HEALTHY. STATISTICAL ANALYSIS USED: GENERAL LINEAR MIXED MODEL ANOVA WAS APPLIED WITH YOGA EXPERIENCE AS A BETWEEN-GROUP FACTOR IN REPEATED MEASURES. INDEPENDENT SAMPLE T-TEST WAS APPLIED FOR BETWEEN GROUP COMPARISON OF RESPIRATORY RATE, DEMOGRAPHIC, AND ANTHROPOMETRIC DATA. P <0.05 IS CONSIDERED STATISTICALLY SIGNIFICANT. RESULTS: BETWEEN-GROUP COMPARISON DURING HDT WITH SPONTANEOUS BREATHING HAS SHOWN A SIGNIFICANTLY LOWER HEART RATE (P = 0.004) WITH HIGHER RR INTERVAL (RRI) (P = 0.002) AND PNN50% (P = 0.019) IN YOGA PRACTITIONERS. THE SEQUENCE BRS (P < 0.0001) AND ALPHA LOW FREQUENCY (LF) OF SPECTRAL BRS (P = 0.035) WERE ALSO SIGNIFICANTLY HIGHER IN THE YOGA GROUP COMPARED TO THE NAIVE GROUP. SIMILARLY, DURING HDT WITH SLOW BREATHING, THE HEART RATE WAS LOWER (P = 0.01); WITH HIGHER RRI (P = 0.009); PNN50% (P = 0.048). STANDARD DEVIATION OF SUCCESSIVE RR INTERVAL DIFFERENCE OF SYSTOLIC BPV WAS LOWER (P = 0.024) WITH HIGHER SEQUENCE BRS (P = 0.001) AND ALPHA LF OF SPECTRAL BRS (P = 0.002) IN YOGA GROUP THAN NAIVE GROUP. CONCLUSION: THE YOGA EXPERIENCED INDIVIDUALS EXHIBIT HIGHER RESTING PARASYMPATHETIC ACTIVITY, LOWER SYSTOLIC BPV, AND HIGHER BRS THAN NAIVE TO YOGA INDIVIDUALS. IT IS INFERRED FROM THE FINDINGS THAT YOGA PRACTITIONERS WERE BETTER ADAPTED TO TRANSIENT CEPHALAD FLUID SHIFT THAT HAPPENS DURING 6 DEGREES HDT. FURTHERMORE, ACUTE SLOW BREATHING DURING 6 DEGREES HDT REDUCED THE SYSTOLIC BLOOD PRESSURE IN ALL THE PARTICIPANTS SUGGESTING THE BENEFICIAL ROLE OF SLOW BREATHING DURING EXPOSURE TO EXTREME CONDITIONS SUCH AS MICROGRAVITY WHICH MIGHT HELP IN THE PREVENTION OF ADVERSE EFFECTS OF CEPHALAD FLUID SHIFT DURING LONG-TERM WEIGHTLESSNESS AND MAINTAIN THE ASTRONAUT HEALTH. FUTURE MECHANISTIC STUDIES WITH ACTIVE YOGA INTERVENTION ARE NECESSARY TO UNDERSTAND THE ADAPTIVE MECHANISMS INVOLVING CENTRAL AND VASCULAR MODULATIONS CONTRIBUTING TO EITHER ATTENUATION OR ACCENTUATION OF THE CARDIOVAGAL BAROREFLEX DURING HDT AND SLOW BREATHING IN HEALTHY INDIVIDUALS.	2021	

8   86 14 A MINDFUL YOGA INTERVENTION FOR YOUNG WOMEN WITH MAJOR DEPRESSIVE DISORDER: DESIGN AND BASELINE SAMPLE CHARACTERISTICS OF A RANDOMIZED CONTROLLED TRIAL. OBJECTIVES: DESPITE THE GAINS MADE BY CURRENT FIRST-LINE INTERVENTIONS FOR MAJOR DEPRESSIVE DISORDER (MDD), MODEST RATES OF TREATMENT RESPONSE AND HIGH RELAPSE INDICATE THE NEED TO AUGMENT EXISTING INTERVENTIONS. FOLLOWING THEORY AND INITIAL RESEARCH INDICATING THE PROMISE OF MINDFUL YOGA INTERVENTIONS (MYIS), THIS STUDY EXAMINES MINDFUL YOGA AS A TREATMENT OF MDD. METHODS/DESIGN: THIS RANDOMIZED CONTROLLED TRIAL USES A SAMPLE OF YOUNG FEMALES (18-34 YEARS) TO EXAMINE THE EFFICACY AND COST-EFFECTIVENESS OF A 9-WEEK MANUALIZED MYI ADDED TO TREATMENT AS USUAL (TAU) VERSUS TAU ALONE. PRIMARY OUTCOME MEASURES CONSIST OF CLINICIAN-ADMINISTERED (HAMILTON DEPRESSION RATING SCALE) AND SELF-REPORT (DEPRESSION-ANXIETY-STRESS SCALES) MEASURES OF DEPRESSION. UNDERLYING MECHANISMS WILL BE EXAMINED, INCLUDING RUMINATION, NEGATIVE SELF-EVALUATION, INTOLERANCE OF UNCERTAINTY, INTEROCEPTIVE AWARENESS, AND DISPOSITIONAL MINDFULNESS. ASSESSMENTS WERE CONDUCTED AT PREINTERVENTION AND WILL BE CONDUCTED AT POSTINTERVENTION, 6-, AND 12-MONTH FOLLOW UP. RESULTS: THE BASELINE SAMPLE CONSISTS OF 171 FEMALES (88 WERE RANDOMIZED INTO THE MYI), REPORTING A BASELINE MAGE = 25.08 YEARS (SDAGE = 4.64), MHAMILTON-DEPRESSION = 18.39 (SDHAMILTON = 6.00), AND A MDASS-DEPRESSION = 21.02 (SDDASS = 9.36). CONCLUSION: THIS TRIAL WILL PROVIDE IMPORTANT INFORMATION REGARDING THE BENEFITS OF ADDING YOGA-BASED INTERVENTIONS TO TAU FOR YOUNG WOMEN WITH MDD AND THE MECHANISMS THROUGH WHICH SUCH BENEFITS MAY OCCUR.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
9 1298 16 HATHA YOGA AND VASCULAR FUNCTION: RESULTS FROM CROSS-SECTIONAL AND INTERVENTIONAL STUDIES. THE AIM OF THIS STUDY WAS TO DETERMINE THE EFFECT OF HATHA YOGA ON ARTERIAL ELASTICITY AND ENDOTHELIAL FUNCTION. FIRST, A CROSS-SECTIONAL STUDY WAS PERFORMED TO DETERMINE WHETHER YOGA PRACTITIONERS WOULD DEMONSTRATE GREATER ARTERIAL COMPLIANCE AND ENDOTHELIUM-DEPENDENT VASODILATION THAN THEIR SEDENTARY PEERS. SECOND, AN INTERVENTION STUDY INVOLVING 13 SEDENTARY MIDDLE-AGED AND OLDER ADULTS (51 +/- 7 YEARS) WAS PERFORMED TO DETERMINE WHETHER 12 WEEKS OF HATHA YOGA WOULD ELICIT INCREASES IN ARTERIAL COMPLIANCE AND ENDOTHELIAL FUNCTION. IN THE CROSS-SECTIONAL STUDY INVOLVING A TOTAL OF 34 SUBJECTS, THERE WERE NO GROUP DIFFERENCES IN BODY FATNESS, BLOOD LIPID AND LIPOPROTEIN CONCENTRATIONS, CAROTID ARTERY COMPLIANCE OR BRACHIAL ARTERY FLOW-MEDIATED DILATION (FMD). HEMOGLOBIN A1C WAS LOWER IN YOGA PRACTITIONERS THAN IN SEDENTARY ADULTS (P < 0.05). TOTAL CHOLESTEROL AND HEMOGLOBIN A1C DECREASED AFTER THE INTERVENTION (P < 0.05) WHILE CAROTID ARTERY COMPLIANCE AND BRACHIAL ARTERY FMD DID NOT CHANGE. THE RESULTS OF BOTH CROSS-SECTIONAL AND INTERVENTIONAL STUDIES INDICATE THAT REGULAR PRACTICE OF HATHA YOGA IS NOT ASSOCIATED WITH IMPROVEMENTS IN VASCULAR FUNCTIONS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
10  438 19 CARDIOVASCULAR AND RESPIRATORY EFFECT OF YOGIC SLOW BREATHING IN THE YOGA BEGINNER: WHAT IS THE BEST APPROACH? SLOW BREATHING INCREASES CARDIAC-VAGAL BAROREFLEX SENSITIVITY (BRS), IMPROVES OXYGEN SATURATION, LOWERS BLOOD PRESSURE, AND REDUCES ANXIETY. WITHIN THE YOGA TRADITION SLOW BREATHING IS OFTEN PAIRED WITH A CONTRACTION OF THE GLOTTIS MUSCLES. THIS RESISTANCE BREATH "UJJAYI" IS PERFORMED AT VARIOUS RATES AND RATIOS OF INSPIRATION/EXPIRATION. TO TEST WHETHER UJJAYI HAD ADDITIONAL POSITIVE EFFECTS TO SLOW BREATHING, WE COMPARED BRS AND VENTILATORY CONTROL UNDER DIFFERENT BREATHING PATTERNS (EQUAL/UNEQUAL INSPIRATION/EXPIRATION AT 6 BREATH/MIN, WITH/WITHOUT UJJAYI), IN 17 YOGA-NAIVE YOUNG HEALTHY PARTICIPANTS. BRS INCREASED WITH SLOW BREATHING TECHNIQUES WITH OR WITHOUT EXPIRATORY UJJAYI (P < 0.05 OR HIGHER) EXCEPT WITH INSPIRATORY + EXPIRATORY UJJAYI. THE MAXIMAL INCREASE IN BRS AND DECREASE IN BLOOD PRESSURE WERE FOUND IN SLOW BREATHING WITH EQUAL INSPIRATION AND EXPIRATION. THIS CORRESPONDED WITH A SIGNIFICANT IMPROVEMENT IN OXYGEN SATURATION WITHOUT INCREASE IN HEART RATE AND VENTILATION. UJJAYI SHOWED SIMILAR INCREASE IN OXYGEN SATURATION BUT SLIGHTLY LESSER IMPROVEMENT IN BAROREFLEX SENSITIVITY WITH NO CHANGE IN BLOOD PRESSURE. THE SLOW BREATHING WITH EQUAL INSPIRATION AND EXPIRATION SEEMS THE BEST TECHNIQUE FOR IMPROVING BAROREFLEX SENSITIVITY IN YOGA-NAIVE SUBJECTS. THE EFFECTS OF UJJAYI SEEMS DEPENDENT ON INCREASED INTRATHORACIC PRESSURE THAT REQUIRES GREATER EFFORT THAN NORMAL SLOW BREATHING.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
11 2076 17 THE EFFECT OF BIKRAM YOGA ON ENDOTHELIAL FUNCTION IN YOUNG AND MIDDLE-AGED AND OLDER ADULTS. THE PURPOSE OF THIS INVESTIGATION WAS TO DETERMINE IF BIKRAM YOGA, A STYLE OF HEATED HATHA YOGA, WOULD IMPROVE ENDOTHELIAL FUNCTION IN YOUNG AND MIDDLE-AGED AND OLDER, HEALTHY ADULTS. THIS TRIAL WAS PERFORMED IN 36 YOUNG (N = 17) AND MIDDLE-AGED AND OLDER ADULTS (N = 19) WHO COMPLETED 3 WEEKLY BIKRAM YOGA CLASSES FOR 8 WEEKS. HEIGHT, BODY WEIGHT AND BODY COMPOSITION WERE DETERMINED AND ENDOTHELIAL FUNCTION WAS MEASURED NONINVASIVELY USING BRACHIAL ARTERY FLOW-MEDIATED DILATION (FMD) BEFORE AND AFTER THE INTERVENTION. NO CHANGES IN BODY WEIGHT, BMI OR BODY FAT PERCENTAGE OCCURRED AS A RESULT OF THE INTERVENTION IN EITHER GROUP. BRACHIAL ARTERY FMD WAS SIGNIFICANTLY INCREASED IN MIDDLE-AGED AND OLDER (P < 0.05) BUT NOT IN YOUNG ADULTS AS A RESULT OF THE INTERVENTION. THE RESULTS DEMONSTRATE THAT A RELATIVELY SHORT-TERM BIKRAM YOGA PRACTICE MIGHT SIGNIFICANTLY IMPROVE VASCULAR ENDOTHELIAL FUNCTION IN MIDDLE-AGED AND OLDER ADULTS. WHILE APPARENTLY HEALTHY INDIVIDUALS IN THIS STUDY EXPERIENCED NO ADVERSE EVENTS, THOSE WITH PREEXISTING CONDITIONS SHOULD TAKE CAUTION AND CONSULT WITH A PHYSICIAN PRIOR TO ENGAGING IN THIS STYLE OF YOGA.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
12  967 15 EFFECTS OF AEROBIC EXERCISE TRAINING AND YOGA ON THE BAROREFLEX IN HEALTHY ELDERLY PERSONS. IT IS UNCLEAR WHETHER THE AGE-ASSOCIATED REDUCTION IN BAROREFLEX SENSITIVITY IS MODIFIABLE BY EXERCISE TRAINING. THE EFFECTS OF AEROBIC EXERCISE TRAINING AND YOGA, A NON-AEROBIC CONTROL INTERVENTION, ON THE BAROREFLEX OF ELDERLY PERSONS WAS DETERMINED. BAROREFLEX SENSITIVITY WAS QUANTIFIED BY THE ALPHA-INDEX, AT HIGH FREQUENCY (HF; 0.15-0.35 HZ, REFLECTING PARASYMPATHETIC ACTIVITY) AND MID-FREQUENCY (MF; 0.05-0.15 HZ, REFLECTING SYMPATHETIC ACTIVITY AS WELL), DERIVED FROM SPECTRAL AND CROSS-SPECTRAL ANALYSIS OF SPONTANEOUS FLUCTUATIONS IN HEART RATE AND BLOOD PRESSURE. TWENTY-SIX (10 WOMEN) SEDENTARY, HEALTHY, NORMOTENSIVE ELDERLY (MEAN 68 YEARS, RANGE 62-81 YEARS) SUBJECTS WERE STUDIED. FOURTEEN (4 WOMEN) OF THE SEDENTARY ELDERLY SUBJECTS COMPLETED 6 WEEKS OF AEROBIC TRAINING, WHILE THE OTHER 12 (6 WOMEN) SUBJECTS COMPLETED 6 WEEKS OF YOGA. HEART RATE DECREASED FOLLOWING YOGA (69 +/- 8 VS. 61 +/- 7 MIN-1, P < 0.05) BUT NOT AEROBIC TRAINING (66 +/- 8 VS. 63 +/- 9 MIN-1, P = 0.29). VO2 MAX INCREASED BY 11% FOLLOWING YOGA (P < 0.01) AND BY 24% FOLLOWING AEROBIC TRAINING (P < 0.01). NO SIGNIFICANT CHANGE IN ALPHA MF (6.5 +/- 3.5 VS. 6.2 +/- 3.0 MS MMHG-1, P = 0.69) OR ALPHA HF (8.5 +/- 4.7 VS. 8.9 +/- 3.5 MS MMHG-1, P = 0.65) OCCURRED AFTER AEROBIC TRAINING. FOLLOWING YOGA, ALPHA HF (8.0 +/- 3.6 VS. 11.5 +/- 5.2 MS MMHG-1, P < 0.01) BUT NOT ALPHA MF (6.5 +/- 3.0 VS. 7.6 +/- 2.8 MS MMHG-1, P = 0.29) INCREASED. SHORT-DURATION AEROBIC TRAINING DOES NOT MODIFY THE ALPHA-INDEX AT ALPHA MF OR ALPHA HF IN HEALTHY NORMOTENSIVE ELDERLY SUBJECTS. ALPHA HF BUT NOT ALPHA MF INCREASED FOLLOWING YOGA, SUGGESTING THAT THESE PARAMETERS ARE MEASURING DISTINCT ASPECTS OF THE BAROREFLEX THAT ARE SEPARATELY MODIFIABLE.	1997	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
13  369 16 AUTONOMIC FUNCTIONS IN RAJA-YOGA MEDITATORS. STRESS, AN INEVITABLE AND CONSTANT FEATURE THROUGHOUT THE LIFETIME, INDUCES AUTONOMIC DYSFUNCTIONS, FOR WHICH MEDITATION IS CONSIDERED TO BE AN ANTIDOTE. SO THE CASE CONTROL STUDY WAS PLANNED INCLUDING 50 RAJA-YOGA MEDITATORS PRACTICING MEDITATION FOR 5 YEARS AND 50 AGE MATCHED NON-MEDITATORS. AUTONOMIC FUNCTION TESTS WERE PERFORMED AND RESULTS WERE COMPARED USING THE STUDENT-T TEST. MEAN VALUES OF RESTING HR, SBP AND DBP WERE LESS IN MEDITATORS. GALVANIC SKIN RESPONSE IN MEDITATORS WAS SIGNIFICANTLY MORE (P < 0.001). MEAN INCREASE BP RESPONSE TO HAND GRIP TEST AND COLD PRESSOR TEST WAS SIGNIFICANTLY LESS IN MEDITATORS THAN NON-MEDITATORS (P < 0.001). STANDING: LYING RATIO, VALSALVA RATIO, INSPIRATION: EXPIRATION RATIO AND 30:15 RATIOS WERE SIGNIFICANTLY INCREASED IN MEDITATORS THAN NON-MEDITATORS. FROM THE RESULTS, THERE WAS SHIFTING OF THE AUTONOMIC BALANCE TO PARASYMPATHETIC SIDE IN RAJA-YOGA MEDITATORS, WHICH SUGGESTS ITS UTILITY TO COMBAT THE ILL EFFECTS OF STRESS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
14  439 15 CARDIOVASCULAR, CELLULAR, AND NEURAL ADAPTATIONS TO HOT YOGA VERSUS NORMAL-TEMPERATURE YOGA. CONTEXT: CHRONIC HEAT EXPOSURE PROMOTES CARDIOVASCULAR AND CELLULAR ADAPTATIONS, IMPROVING AN ORGANISM'S ABILITY TO TOLERATE SUBSEQUENT STRESSORS. HEAT EXPOSURE MAY ALSO PROMOTE NEURAL ADAPTATIONS AND ALTER THE NEURAL-HORMONAL STRESS RESPONSE. HOT-TEMPERATURE YOGA (HY) COMBINES MIND-BODY EXERCISE WITH HEAT EXPOSURE. THE ADDED HEAT COMPONENT IN HY MAY INDUCE CARDIOVASCULAR AND CELLULAR CHANGES, ALONG WITH NEURAL BENEFITS AND MODULATION OF STRESS HORMONES. AIMS: THE PURPOSE OF THE PRESENT STUDY IS TO COMPARE THE CARDIOVASCULAR, CELLULAR HEAT SHOCK PROTEIN 70 (HSP70), NEURAL, AND HORMONAL ADAPTATIONS OF HY VERSUS NORMAL-TEMPERATURE YOGA (NY). SETTINGS AND DESIGN: TWENTY-TWO SUBJECTS (MALES = 11 AND FEMALES = 11, 26 +/- 6 YEARS) COMPLETED 4 WEEKS OF NY (N = 11) OR HY (N = 11, 41 DEGREES C, 40% HUMIDITY). YOGA SESSIONS WERE PERFORMED 3 TIMES/WEEK FOLLOWING A MODIFIED BIKRAM PROTOCOL. SUBJECTS AND METHODS: PRE- AND POSTTESTING INCLUDED (1) HEMODYNAMIC MEASURES DURING A HEAT TOLERANCE TEST AND MAXIMAL AEROBIC FITNESS TEST; (2) NEURAL AND HORMONAL ADAPTATIONS USING SERUM BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) AND ADRENOCORTICOTROPIC HORMONE (ACTH), ALONG WITH A MENTAL STRESS QUESTIONNAIRE; AND (3) CELLULAR ADAPTATIONS (HSP70) IN PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS). STATISTICAL ANALYSIS: WITHIN- AND BETWEEN-GROUP STUDENT'S T-TEST ANALYSES WERE CONDUCTED TO COMPARE PRE- AND POST-VO2 MAX, PERCEIVED STRESS, BDNF, HSP70, AND ACTH IN HY AND NY GROUPS. RESULTS: MAXIMAL AEROBIC FITNESS INCREASED IN THE HY GROUP ONLY. NO EVIDENCE OF HEAT ACCLIMATION OR CHANGE IN MENTAL STRESS WAS OBSERVED. SERUM BDNF SIGNIFICANTLY INCREASED IN YOGA GROUPS COMBINED. ANALYSIS OF HSP70 SUGGESTED HIGHER EXPRESSION OF HSP70 IN THE HY GROUP ONLY. CONCLUSIONS: TWELVE SESSIONS OF HY PROMOTED CARDIOVASCULAR FITNESS AND CELLULAR THERMOTOLERANCE ADAPTATIONS. SERUM BDNF INCREASED IN RESPONSE TO YOGA (NY + HY) AND APPEARED TO NOT BE TEMPERATURE DEPENDENT.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
15 2775 21 YOGA RESPIRATORY TRAINING IMPROVES RESPIRATORY FUNCTION AND CARDIAC SYMPATHOVAGAL BALANCE IN ELDERLY SUBJECTS: A RANDOMISED CONTROLLED TRIAL. OBJECTIVES: SINCE AGEING IS ASSOCIATED WITH A DECLINE IN PULMONARY FUNCTION, HEART RATE VARIABILITY AND SPONTANEOUS BAROREFLEX, AND RECENT STUDIES SUGGEST THAT YOGA RESPIRATORY EXERCISES MAY IMPROVE RESPIRATORY AND CARDIOVASCULAR FUNCTION, WE HYPOTHESISED THAT YOGA RESPIRATORY TRAINING MAY IMPROVE RESPIRATORY FUNCTION AND CARDIAC AUTONOMIC MODULATION IN HEALTHY ELDERLY SUBJECTS. DESIGN: 76 HEALTHY ELDERLY SUBJECTS WERE ENROLLED IN A RANDOMISED CONTROL TRIAL IN BRAZIL AND 29 COMPLETED THE STUDY (AGE 68 +/- 6 YEARS, 34% MALES, BODY MASS INDEX 25 +/- 3 KG/M(2)). SUBJECTS WERE RANDOMISED INTO A 4-MONTH TRAINING PROGRAM (2 CLASSES/WEEK PLUS HOME EXERCISES) OF EITHER STRETCHING (CONTROL, N=14) OR RESPIRATORY EXERCISES (YOGA, N=15). YOGA RESPIRATORY EXERCISES (BHASTRIKA) CONSISTED OF RAPID FORCED EXPIRATIONS FOLLOWED BY INSPIRATION THROUGH THE RIGHT NOSTRIL, INSPIRATORY APNOEA WITH GENERATION OF INTRATHORACIC NEGATIVE PRESSURE, AND EXPIRATION THROUGH THE LEFT NOSTRIL. PULMONARY FUNCTION, MAXIMUM EXPIRATORY AND INSPIRATORY PRESSURES (PE(MAX) AND PI(MAX), RESPECTIVELY), HEART RATE VARIABILITY AND BLOOD PRESSURE VARIABILITY FOR SPONTANEOUS BAROREFLEX DETERMINATION WERE DETERMINED AT BASELINE AND AFTER 4 MONTHS. RESULTS: SUBJECTS IN BOTH GROUPS HAD SIMILAR DEMOGRAPHIC PARAMETERS. PHYSIOLOGICAL VARIABLES DID NOT CHANGE AFTER 4 MONTHS IN THE CONTROL GROUP. HOWEVER, IN THE YOGA GROUP, THERE WERE SIGNIFICANT INCREASES IN PE(MAX) (34%, P<0.0001) AND PI(MAX) (26%, P<0.0001) AND A SIGNIFICANT DECREASE IN THE LOW FREQUENCY COMPONENT (A MARKER OF CARDIAC SYMPATHETIC MODULATION) AND LOW FREQUENCY/HIGH FREQUENCY RATIO (MARKER OF SYMPATHOVAGAL BALANCE) OF HEART RATE VARIABILITY (40%, P<0.001). SPONTANEOUS BAROREFLEX DID NOT CHANGE, AND QUALITY OF LIFE ONLY MARGINALLY INCREASED IN THE YOGA GROUP. CONCLUSION: RESPIRATORY YOGA TRAINING MAY BE BENEFICIAL FOR THE ELDERLY HEALTHY POPULATION BY IMPROVING RESPIRATORY FUNCTION AND SYMPATHOVAGAL BALANCE. TRIAL REGISTRATION CINICALTRIALS.GOV IDENTIFIER: NCT00969345; TRIAL REGISTRY NAME: EFFECTS OF RESPIRATORY YOGA TRAINING (BHASTRIKA) ON HEART RATE VARIABILITY AND BAROREFLEX, AND QUALITY OF LIFE OF HEALTHY ELDERLY SUBJECTS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
16  741 16 EFFECT OF REGULAR YOGA PRACTICE ON RESPIRATORY REGULATION AND EXERCISE PERFORMANCE. YOGA ALTERS SPONTANEOUS RESPIRATORY REGULATION AND REDUCES HYPOXIC AND HYPERCAPNIC VENTILATORY RESPONSES. SINCE A LOWER VENTILATORY RESPONSE IS ASSOCIATED WITH AN IMPROVED ENDURANCE CAPACITY DURING WHOLE-BODY EXERCISE, WE TESTED WHETHER YOGIC SUBJECTS (YOGA) SHOW AN INCREASED ENDURANCE CAPACITY COMPARED TO MATCHED NON-YOGIC INDIVIDUALS (CON) WITH SIMILAR PHYSICAL ACTIVITY LEVELS. RESTING VENTILATION, THE VENTILATORY RESPONSE TO HYPERCAPNIA, PASSIVE LEG MOVEMENT AND EXERCISE, AS WELL AS ENDURANCE PERFORMANCE WERE ASSESSED. YOGA (N = 9), COMPARED TO CONTROL (N = 6), HAD A HIGHER TIDAL VOLUME AT REST (0.7+/-0.2 VS. 0.5+/-0.1 L, P = 0.034) AND A REDUCED VENTILATORY RESPONSE TO HYPERCAPNIA (33+/-15 VS. 47+/-15 L.MIN(-1), P = 0.048). A YOGA SUBGROUP (N = 6) WITH MAXIMAL PERFORMANCE SIMILAR TO CONTROL SHOWED A BLUNTED VENTILATORY RESPONSE TO PASSIVE CYCLING (11+/-2 VS. 14+/-2 L.MIN(-1), P = 0.039) AND A TENDENCY TOWARDS LOWER EXERCISE VENTILATION (33+/-2 VS. 36+/-3 L.MIN(-1), P = 0.094) WHILE CYCLING ENDURANCE (YOGA: 17.3+/-3.3; CON: 19.6+/-8.5 MIN, P = 0.276) DID NOT DIFFER. THUS, YOGA PRACTICE WAS NOT ASSOCIATED WITH IMPROVED EXERCISE CAPACITY NOR WITH SIGNIFICANT CHANGES IN EXERCISE VENTILATION DESPITE A SIGNIFICANTLY DIFFERENT RESPIRATORY REGULATION AT REST AND IN RESPONSE TO HYPERCAPNIA AND PASSIVE LEG MOVEMENT.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
17 2072 19 THE EFFECT OF A SIX-WEEK PROGRAM OF YOGA AND MEDITATION ON BRACHIAL ARTERY REACTIVITY: DO PSYCHOSOCIAL INTERVENTIONS AFFECT VASCULAR TONE? BACKGROUND: CHRONIC STRESS IS ESTIMATED TO INCREASE THE RISK OF CARDIOVASCULAR (CV) EVENTS TWO-FOLD. ALTHOUGH STRESS REDUCTION HAS BEEN LINKED TO A REDUCTION IN CV EVENTS, LITTLE IS KNOWN REGARDING ITS EXACT MECHANISM OF BENEFIT. HYPOTHESIS: YOGA AND MEDITATION WILL IMPROVE PARAMETERS OF ENDOTHELIAL FUNCTION. METHODS: WE EXAMINED THE EFFECTS OF YOGA AND MEDITATION ON HEMODYNAMIC AND LABORATORY PARAMETERS AS WELL AS ON ENDOTHELIAL FUNCTION IN A 6-WEEK PILOT STUDY. SYSTOLIC AND DIASTOLIC BLOOD PRESSURES, HEART RATE, BODY MASS INDEX (BMI), FASTING GLUCOSE, LIPIDS, HS C-REACTIVE PROTEIN (CRP), AND ENDOTHELIAL FUNCTION (AS ASSESSED BY BRACHIAL ARTERY REACTIVITY) WERE ALL STUDIED AT BASELINE AND AFTER 6 WEEKS OF YOGA PRACTICE. RESULTS: A COURSE IN YOGA AND MEDITATION WAS GIVEN TO THE SUBJECTS FOR 1.5 H THREE TIMES WEEKLY FOR 6 WEEKS AND SUBJECTS WERE INSTRUCTED TO CONTINUE THEIR EFFORTS AT HOME. THIS PROSPECTIVE COHORT STUDY INCLUDED 33 SUBJECTS (MEAN AGE 55 +/- 11 YEARS) BOTH WITH (30%) AND WITHOUT (70%) ESTABLISHED CORONARY ARTERY DISEASE (CAD). THERE WERE SIGNIFICANT REDUCTIONS IN BLOOD PRESSURE, HEART RATE, AND BMI IN THE TOTAL COHORT WITH YOGA. NONE OF THE LABORATORY PARAMETERS CHANGED SIGNIFICANTLY WITH YOGA. FOR THE TOTAL COHORT THERE WAS NO SIGNIFICANT IMPROVEMENT IN ENDOTHELIAL-DEPENDENT VASODILATATION WITH YOGA TRAINING AND MEDITATION COMPARED WITH BASELINE (16.7% RELATIVE IMPROVEMENT FROM 7.2-8.4%; P = 0.3). IN THE GROUP WITH CAD, ENDOTHELIAL-DEPENDENT VASODILATATION IMPROVED 69% WITH YOGA TRAINING (6.38-10.78%; P = 0.09). CONCLUSION: YOGA AND MEDITATION APPEAR TO IMPROVE ENDOTHELIAL FUNCTION IN SUBJECTS WITH CAD.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
18  404 16 BIKRAM YOGA TRAINING AND PHYSICAL FITNESS IN HEALTHY YOUNG ADULTS. THERE HAS BEEN RELATIVELY LITTLE LONGITUDINAL CONTROLLED INVESTIGATION OF THE EFFECTS OF YOGA ON GENERAL PHYSICAL FITNESS, DESPITE THE WIDESPREAD PARTICIPATION IN THIS FORM OF EXERCISE. THE PURPOSE OF THIS EXPLORATORY STUDY WAS TO EXAMINE THE EFFECT OF SHORT-TERM BIKRAM YOGA TRAINING ON GENERAL PHYSICAL FITNESS. YOUNG HEALTHY ADULTS WERE RANDOMIZED TO YOGA TRAINING (N = 10, 29 +/- 6 YEARS, 24 SESSIONS IN 8 WEEKS) OR A CONTROL GROUP (N = 11, 26 +/- 7 YEARS). EACH YOGA TRAINING SESSION CONSISTED OF 90-MINUTE STANDARDIZED SUPERVISED POSTURES PERFORMED IN A HEATED AND HUMIDIFIED STUDIO. ISOMETRIC DEADLIFT STRENGTH, HANDGRIP STRENGTH, LOWER BACK/HAMSTRING AND SHOULDER FLEXIBILITY, RESTING HEART RATE AND BLOOD PRESSURE, MAXIMAL OXYGEN CONSUMPTION (TREADMILL), AND LEAN AND FAT MASS (DUAL-ENERGY X-RAY ABSORPTIOMETRY) WERE MEASURED BEFORE AND AFTER TRAINING. YOGA SUBJECTS EXHIBITED INCREASED DEADLIFT STRENGTH, SUBSTANTIALLY INCREASED LOWER BACK/HAMSTRING FLEXIBILITY, INCREASED SHOULDER FLEXIBILITY, AND MODESTLY DECREASED BODY FAT COMPARED WITH CONTROL GROUP. THERE WERE NO CHANGES IN HANDGRIP STRENGTH, CARDIOVASCULAR MEASURES, OR MAXIMAL AEROBIC FITNESS. IN SUMMARY, THIS SHORT-TERM YOGA TRAINING PROTOCOL PRODUCED BENEFICIAL CHANGES IN MUSCULOSKELETAL FITNESS THAT WERE SPECIFIC TO THE TRAINING STIMULUS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
19 1322 17 HEMODYNAMIC AND PRESSOR RESPONSES TO COMBINATION OF YOGA AND BLOOD FLOW RESTRICTION. A COMBINATION OF YOGA AND BLOOD FLOW RESTRICTION, EACH OF WHICH ELICITS MARKED PRESSOR RESPONSES, MAY FURTHER INCREASE BLOOD PRESSURE AND MYOCARDIAL OXYGEN DEMAND. TO DETERMINE THE IMPACT OF A COMBINATION OF YOGA AND BLOOD FLOW RESTRICTION ON HEMODYNAMIC RESPONSES, TWENTY YOUNG HEALTHY PARTICIPANTS PERFORMED 20 YOGA POSES WITH/WITHOUT BLOOD FLOW RESTRICTION BANDS PLACED ON BOTH LEGS. AT BASELINE, THERE WERE NO SIGNIFICANT DIFFERENCES IN ANY OF THE VARIABLES BETWEEN THE BLOOD FLOW RESTRICTION AND NON-BLOOD FLOW RESTRICTION CONDITIONS. BLOOD PRESSURE AND HEART RATE INCREASED IN RESPONSE TO THE VARIOUS YOGA POSES (P<0.01) BUT WERE NOT DIFFERENT BETWEEN THE BLOOD FLOW RESTRICTION AND NON-BLOOD FLOW RESTRICTION CONDITIONS. RATE-PRESSURE PRODUCTS, AN INDEX OF MYOCARDIAL OXYGEN DEMAND, INCREASED SIGNIFICANTLY DURING YOGA EXERCISES WITH NO SIGNIFICANT DIFFERENCES BETWEEN THE TWO CONDITIONS. RATING OF PERCEIVED EXERTION WAS NOT DIFFERENT BETWEEN THE CONDITIONS. BLOOD LACTATE CONCENTRATION WAS SIGNIFICANTLY GREATER AFTER PERFORMING YOGA WITH BLOOD FLOW RESTRICTION BANDS (P=0.007). CARDIO-ANKLE VASCULAR INDEX, AN INDEX OF ARTERIAL STIFFNESS, DECREASED SIMILARLY AFTER YOGA EXERCISE IN BOTH CONDITIONS WHILE FLOW-MEDIATED DILATION REMAINED UNCHANGED. IN CONCLUSION, THE USE OF LOWER BODY BLOOD FLOW RESTRICTION BANDS IN COMBINATION WITH YOGA DID NOT RESULT IN ADDITIVE OR SYNERGISTIC HEMODYNAMIC AND PRESSOR RESPONSES.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
20  263 22 ACUTE CARDIOVASCULAR RESPONSES TO A SESSION OF BIKRAM YOGA: A PILOT UNCONTROLLED TRIAL. INTRODUCTION: MAIN CARDIOVASCULAR PARAMETERS SUCH AS HEART RATE (HR), BLOOD PRESSURE, AND MYOCARDIAL OXYGEN CONSUMPTION (MOC) ARE TIGHTLY REGULATED BY A MULTIFACTORIAL, NONLINEAR CONTROL SYSTEM. INCREASED HR BECAUSE OF PHYSICAL ACTIVITY IS OFTEN ACCOMPANIED BY AN INCREASE IN BLOOD PRESSURE. POSTURAL CHANGES HAVE AN EFFECT ON THE BARORECEPTORS, AND STRETCHING EXERCISES AND ISOMETRIC CONTRACTIONS MODULATE MUSCLE MECHANORECEPTORS ELICITING INCREASES IN BLOOD PRESSURE. HOWEVER, A HOT ENVIRONMENT INCREASES THE CORE TEMPERATURE INDUCING VASODILATION AND PLASMA VOLUME CHANGES THAT MIGHT CONTRIBUTE TO A DROP IN BLOOD PRESSURE. DURING THE PRACTICE OF BIKRAM YOGA, ALL THESE FACTORS CONVERGE AND LITTLE IS KNOWN ABOUT THE RESULTING CHANGES IN BLOOD PRESSURE AND MOC. METHODS: SIXTEEN APPARENTLY HEALTHY FEMALE VOLUNTEERS, REGULAR PRACTITIONERS OF BIKRAM YOGA, WERE EVALUATED DURING A 90 MIN SESSION. SYSTOLIC BLOOD PRESSURE (SBP) AND DIASTOLIC BLOOD PRESSURE (DBP) WERE MEASURED IMMEDIATELY AFTER EACH POSTURE AND HR WAS MEASURED CONTINUOUSLY DURING THE PRACTICE. RESULTS: HR AND ESTIMATED MOC INCREASED SIGNIFICANTLY OVER BASELINE DURING THE EXERCISE (+62.3% AND +63.6%, RESPECTIVELY). HR MEAN VALUE ACROSS THE ENTIRE BIKRAM YOGA SESSION WAS 126.6 +/- 14.3 BPM REACHING A MAXIMUM OF 168.1 +/- 20.2 BPM. SBP WAS NOT SIGNIFICANTLY INCREASED OVER BASELINE AT ANY TIME DURING THE PRACTICE WITH A MEAN VALUE OF 117.0 +/- 10.1 MMHG AND DBP WAS SIGNIFICANTLY DECREASED OVER BASELINE MOST OF THE TIME (-10.1%, MEAN 71.2 +/- 7.3 MMHG) WITH PARTICULAR DECLINE TOWARD THE END OF THE PRACTICE DURING THE FLOOR POSTURES. CONCLUSIONS: DBP DURING THE PRACTICE OF BIKRAM YOGA WAS SIGNIFICANTLY DIFFERENT FROM THAT PREVIOUSLY REPORTED FOR NONHEATED HATHA YOGA FOR NORMOTENSIVE SUBJECTS. FURTHER STUDIES EVALUATING THE SAME GROUP AT BOTH CONDITIONS ARE NEEDED TO BETTER CHARACTERIZE THE MAGNITUDE OF THE CHANGES IN HR, SBP, DBP, AND MOC.	2019