1 1269 153 FRAILTY MODIFIES THE INTERVENTION EFFECT OF CHAIR YOGA ON PAIN AMONG OLDER ADULTS WITH LOWER EXTREMITY OSTEOARTHRITIS: SECONDARY ANALYSIS OF A NONPHARMACOLOGICAL INTERVENTION TRIAL. OBJECTIVE: IN AN 8-WEEK NONPHARMACOLOGICAL PAIN INTERVENTION TRIAL AMONG OLDER ADULTS WITH LOWER EXTREMITY OSTEOARTHRITIS (OA), WE AIMED TO EXAMINE: A) THE BASELINE FRAILTY LEVEL OF THE PARTICIPANTS; B) WHETHER SUCH INTERVENTION IS MORE BENEFICIAL FOR BASELINE FRAILER OLDER ADULTS THAN FOR THEIR COUNTERPARTS WITH LESS FRAILTY; AND C) WHETHER THE INTERVENTION COULD ALSO ALTER FRAILTY. METHODS: PARTICIPANTS WERE RANDOMLY ASSIGNED TO EITHER CHAIR YOGA (CY) OR HEALTH EDUCATION PROGRAM (HEP) GROUPS AND ATTENDED TWICE-WEEKLY 45-MINUTE CY OR HEP SESSIONS FOR 8 WEEKS. FOLLOWING A STANDARD PROCEDURE, 82 VARIABLES WERE USED TO CONSTRUCT A FRAILTY INDEX (FI, 0-1). PRIMARY OUTCOMES WERE: WESTERN ONTARIO AND MCMASTER UNIVERSITIES (WOMAC) PAIN AND PAIN INTERFERENCE. LINEAR MIXED-EFFECTS MODELS WERE USED TO EVALUATE THE MODIFYING EFFECT OF BASELINE FRAILTY ON THE INTERVENTION EFFECT OF CY ON PRIMARY OUTCOMES. SIMILAR MODELS WERE USED TO EVALUATE THE EFFECT OF CY ON FRAILTY. RESULTS: A TOTAL OF 112 PARTICIPANTS (N = 63 CY, N = 49 HEP; 75.3 [SD = 7.5] YEARS) WITH 85 FEMALES (75.9%) WERE INCLUDED. THE MEAN VALUES OF BASELINE FI FOR THE CY AND HEP GROUPS WERE SIMILAR (0.428 [0.05] AND 0.433 [0.05], P = 0.355). EACH 0.01 INCREMENT IN BASELINE FI WAS ASSOCIATED WITH HIGHER WOMAC PAIN (BETA = 0.28, P < 0.001) AND PAIN INTERFERENCE (BETA = 0.51, P < 0.001). THERE WAS A SIGNIFICANT INTERACTION EFFECT BETWEEN INTERVENTION, TIME, AND BASELINE FI (P = 0.020 FOR WOMAC PAIN; P = 0.010 FOR PAIN INTERFERENCE), INDICATING THAT PARTICIPANTS WITH HIGHER LEVEL OF BASELINE FI HAD GREATER DECLINES IN WOMAC PAIN AND PAIN INTERFERENCE. THERE WAS NO SIGNIFICANTLY GREATER DECLINE IN FI FOR THE CY GROUP COMPARED TO THE HEP GROUP (BETWEEN-GROUP DIFFERENCE - 0.01; P = 0.509) AND THERE WERE NO SIGNIFICANT TREND CHANGES IN FI (P FOR INTERACTION = 0.605). CONCLUSIONS: FRAILTY MODIFIES THE INTERVENTION EFFECT OF CY ON PAIN AMONG OLDER ADULTS WITH LOWER EXTREMITY OA, UNDERSCORING THE IMPORTANCE OF ASSESSING FRAILTY TO IMPROVE THE MANAGEMENT OF PAIN IN THIS POPULATION.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
2 2078  47 THE EFFECT OF CHAIR YOGA ON BIOPSYCHOSOCIAL CHANGES IN ENGLISH- AND SPANISH-SPEAKING COMMUNITY-DWELLING OLDER ADULTS WITH LOWER-EXTREMITY OSTEOARTHRITIS. CHAIR YOGA (CY), A MIND-BODY THERAPY, IS A SAFE NONPHARMACOLOGICAL APPROACH FOR MANAGING OSTEOARTHRITIS (OA) IN OLDER ADULTS WHO CANNOT PARTICIPATE IN STANDING EXERCISE. HOWEVER, THERE IS NO LINGUISTICALLY TAILORED CY PROGRAM FOR THOSE WITH LIMITED ENGLISH PROFICIENCY (LEP). THIS 2-ARM RANDOMIZED CONTROLLED TRIAL COMPARED THE EFFECTS OF A LINGUISTICALLY TAILORED YOGA PROGRAM (ENGLISH AND SPANISH VERSIONS) ON THE OUTCOMES OF PAIN, PHYSICAL FUNCTION, AND PSYCHOSOCIAL FACTORS COMPARED TO THE EFFECTS OF A LINGUISTICALLY TAILORED HEALTH EDUCATION PROGRAM (HEP; ENGLISH AND SPANISH VERSIONS). PARTICIPANTS WITH LOWER-EXTREMITY OA, RECRUITED FROM 2 COMMUNITY SITES, COMPLETED THE SPANISH (N = 40) OR ENGLISH (N = 60) VERSION OF TWICE-WEEKLY 45-MIN CY OR HEP SESSIONS FOR 8 WEEKS. DATA WERE COLLECTED AT BASELINE, 4 WEEKS, 8 WEEKS, AND 1- AND 3-MONTH FOLLOW-UPS. ENGLISH AND SPANISH CY GROUPS (BUT NEITHER HEP LANGUAGE GROUP) SHOWED SIGNIFICANT DECREASES IN PAIN INTERFERENCE. MEASURES OF OA SYMPTOMS, BALANCE, DEPRESSION, AND SOCIAL ACTIVITIES WERE NOT SIGNIFICANTLY DIFFERENT BETWEEN ENGLISH AND SPANISH VERSIONS OF CY AND ENGLISH AND SPANISH VERSIONS OF HEP. IT WAS CONCLUDED THAT THE SPANISH AND ENGLISH VERSIONS OF CY AND HEP WERE EQUIVALENT. LINGUISTICALLY TAILORED CY COULD BE IMPLEMENTED IN AGING-SERVING COMMUNITIES FOR PERSONS WITH LEP.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
3  107  59 A PILOT RANDOMIZED CONTROLLED TRIAL OF THE EFFECTS OF CHAIR YOGA ON PAIN AND PHYSICAL FUNCTION AMONG COMMUNITY-DWELLING OLDER ADULTS WITH LOWER EXTREMITY OSTEOARTHRITIS. OBJECTIVES: TO DETERMINE EFFECTS OF SIT 'N' FIT CHAIR YOGA, COMPARED TO A HEALTH EDUCATION PROGRAM (HEP), ON PAIN AND PHYSICAL FUNCTION IN OLDER ADULTS WITH LOWER EXTREMITY OSTEOARTHRITIS (OA) WHO COULD NOT PARTICIPATE IN STANDING EXERCISE. DESIGN: TWO-ARM RANDOMIZED CONTROLLED TRIAL. SETTING: ONE HUD SENIOR HOUSING FACILITY AND ONE DAY SENIOR CENTER IN SOUTH FLORIDA. PARTICIPANTS: COMMUNITY-DWELLING OLDER ADULTS (N = 131) WERE RANDOMLY ASSIGNED TO CHAIR YOGA (N = 66) OR HEP (N = 65). THIRTEEN DROPPED AFTER ASSIGNMENT BUT PRIOR TO THE INTERVENTION; SIX DROPPED DURING THE INTERVENTION; 106 OF 112 COMPLETED AT LEAST 12 OF 16 SESSIONS (95% RETENTION RATE). INTERVENTIONS: PARTICIPANTS ATTENDED EITHER CHAIR YOGA OR HEP. BOTH INTERVENTIONS CONSISTED OF TWICE-WEEKLY 45-MINUTE SESSIONS FOR 8 WEEKS. MEASUREMENTS: PRIMARY: PAIN, PAIN INTERFERENCE; SECONDARY: BALANCE, GAIT SPEED, FATIGUE, FUNCTIONAL ABILITY MEASURED AT BASELINE, AFTER 4 WEEKS OF INTERVENTION, AT THE END OF THE 8-WEEK INTERVENTION, AND POST-INTERVENTION (1 AND 3 MONTHS). RESULTS: THE CHAIR YOGA GROUP SHOWED GREATER REDUCTION IN PAIN INTERFERENCE DURING THE INTERVENTION (P = .01), SUSTAINED THROUGH 3 MONTHS (P = .022). WOMAC PAIN (P = .048), GAIT SPEED (P = .024), AND FATIGUE (P = .037) WERE IMPROVED IN THE YOGA GROUP DURING THE INTERVENTION (P = .048) BUT IMPROVEMENTS WERE NOT SUSTAINED POST INTERVENTION. CHAIR YOGA HAD NO EFFECT ON BALANCE. CONCLUSION: AN 8-WEEK CHAIR YOGA PROGRAM WAS ASSOCIATED WITH REDUCTION IN PAIN, PAIN INTERFERENCE, AND FATIGUE, AND IMPROVEMENT IN GAIT SPEED, BUT ONLY THE EFFECTS ON PAIN INTERFERENCE WERE SUSTAINED 3 MONTHS POST INTERVENTION. CHAIR YOGA SHOULD BE FURTHER EXPLORED AS A NONPHARMACOLOGIC INTERVENTION FOR OLDER PEOPLE WITH OA IN THE LOWER EXTREMITIES. TRIAL REGISTRATION: CLINICALTRIALS.GOV: NCT02113410.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
4  120  25 A PILOT STUDY OF THE EFFECTS OF CHAIR YOGA AND CHAIR-BASED EXERCISE ON BIOPSYCHOSOCIAL OUTCOMES IN OLDER ADULTS WITH LOWER EXTREMITY OSTEOARTHRITIS. THIS PILOT STUDY EXAMINED WHETHER CHAIR YOGA AND CHAIR-BASED EXERCISE ARE EFFECTIVE IN MANAGING BIOPSYCHOSOCIAL OUTCOMES FOR OLDER ADULTS WITH LOWER EXTREMITY OSTEOARTHRITIS. BOTH INTERVENTIONS IMPROVED PHYSICAL FUNCTION AND MOBILITY OVER TIME, ALTHOUGH NO SIGNIFICANT DIFFERENCES BETWEEN THE 2 INTERVENTIONS WERE IDENTIFIED.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
5 2590  59 YOGA FOR MANAGING KNEE OSTEOARTHRITIS IN OLDER WOMEN: A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: OSTEOARTHRITIS (OA) IS A COMMON PROBLEM IN OLDER WOMEN THAT IS ASSOCIATED WITH PAIN AND DISABILITIES. ALTHOUGH YOGA IS RECOMMENDED AS AN EXERCISE INTERVENTION TO MANAGE ARTHRITIS, THERE IS LIMITED EVIDENCE DOCUMENTING ITS EFFECTIVENESS, WITH LITTLE KNOWN ABOUT ITS LONG TERM BENEFITS. THIS STUDY'S AIMS WERE TO ASSESS THE FEASIBILITY AND POTENTIAL EFFICACY OF A HATHA YOGA EXERCISE PROGRAM IN MANAGING OA-RELATED SYMPTOMS IN OLDER WOMEN WITH KNEE OA. METHODS: ELIGIBLE PARTICIPANTS (N=36; MEAN AGE 72 YEARS) WERE RANDOMLY ASSIGNED TO 8-WEEK YOGA PROGRAM INVOLVING GROUP AND HOME-BASED SESSIONS OR WAIT-LIST CONTROL. THE YOGA INTERVENTION PROGRAM WAS DEVELOPED BY A GROUP OF YOGA EXPERTS (N=5). THE PRIMARY OUTCOME WAS THE WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX (WOMAC) TOTAL SCORE THAT MEASURES KNEE OA PAIN, STIFFNESS, AND FUNCTION AT 8 WEEKS. THE SECONDARY OUTCOMES, PHYSICAL FUNCTION OF THE LOWER EXTREMITIES, BODY MASS INDEX (BMI), QUALITY OF SLEEP (QOS), AND QUALITY OF LIFE (QOL), WERE MEASURED USING WEIGHT, HEIGHT, THE SHORT PHYSICAL PERFORMANCE BATTERY (SPPB), THE PITTSBURGH SLEEP QUALITY INDEX (PSQI), THE CANTRIL SELF-ANCHORING LADDER, AND THE SF12V2 HEALTH SURVEY. DATA WERE COLLECTED AT BASELINE, 4 WEEKS AND 8 WEEKS, AND 20 WEEKS. RESULTS: THE RECRUITMENT TARGET WAS MET, WITH STUDY RETENTION AT 95%. BASED ON ANCOVAS, PARTICIPANTS IN THE TREATMENT GROUP EXHIBITED SIGNIFICANTLY GREATER IMPROVEMENT IN WOMAC PAIN (ADJUSTED MEANS [SE]) (8.3 [.67], 5.8 [.67]; P=.01), STIFFNESS (4.7 [.28], 3.4 [.28]; P=.002) AND SPPB (REPEATED CHAIR STANDS) (2.0 [.23], 2.8 [.23]; P=.03) AT 8 WEEKS. SIGNIFICANT TREATMENT AND TIME EFFECTS WERE SEEN IN WOMAC PAIN (7.0 [.46], 5.4 [.54]; P=.03), FUNCTION (24.5 [1.8], 19.9 [1.6]; P=.01) AND TOTAL SCORES (35.4 [2.3], 28.6 [2.1]; P=.01) FROM 4 TO 20 WEEKS. SLEEP DISTURBANCE WAS IMPROVED BUT THE PSQI TOTAL SCORE DECLINED SIGNIFICANTLY AT 20 WEEKS. CHANGES IN BMI AND QOL WERE NOT SIGNIFICANT. NO YOGA RELATED ADVERSE EVENTS WERE OBSERVED. CONCLUSIONS: A WEEKLY YOGA PROGRAM WITH HOME PRACTICE IS FEASIBLE, ACCEPTABLE, AND SAFE FOR OLDER WOMEN WITH KNEE OA, AND SHOWS THERAPEUTIC BENEFITS. TRIAL REGISTRATION: CLINICALTRIALS.GOV: NCT01832155.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
6  518  45 COMPARING ONCE- VERSUS TWICE-WEEKLY YOGA CLASSES FOR CHRONIC LOW BACK PAIN IN PREDOMINANTLY LOW INCOME MINORITIES: A RANDOMIZED DOSING TRIAL. BACKGROUND. PREVIOUS STUDIES HAVE DEMONSTRATED THAT ONCE-WEEKLY YOGA CLASSES ARE EFFECTIVE FOR CHRONIC LOW BACK PAIN (CLBP) IN WHITE ADULTS WITH HIGH SOCIOECONOMIC STATUS. THE COMPARATIVE EFFECTIVENESS OF TWICE-WEEKLY CLASSES AND GENERALIZABILITY TO RACIALLY DIVERSE LOW INCOME POPULATIONS ARE UNKNOWN. METHODS. WE CONDUCTED A 12-WEEK RANDOMIZED, PARALLEL-GROUP, DOSING TRIAL FOR 95 ADULTS RECRUITED FROM AN URBAN SAFETY-NET HOSPITAL AND FIVE COMMUNITY HEALTH CENTERS COMPARING ONCE-WEEKLY (N = 49) VERSUS TWICE-WEEKLY (N = 46) STANDARDIZED YOGA CLASSES SUPPLEMENTED BY HOME PRACTICE. PRIMARY OUTCOMES WERE CHANGE FROM BASELINE TO 12 WEEKS IN PAIN (11-POINT SCALE) AND BACK-RELATED FUNCTION (23-POINT MODIFIED ROLAND-MORRIS DISABILITY QUESTIONNAIRE). RESULTS. 82% OF PARTICIPANTS WERE NONWHITE; 77% HAD ANNUAL HOUSEHOLD INCOMES <$40,000. THE SAMPLE'S BASELINE MEAN PAIN INTENSITY [6.9 (SD 1.6)] AND FUNCTION [13.7 (SD 5.0)] REFLECTED MODERATE TO SEVERE BACK PAIN AND IMPAIRMENT. PAIN AND BACK-RELATED FUNCTION IMPROVED WITHIN BOTH GROUPS (P < 0.001). HOWEVER, THERE WERE NO DIFFERENCES BETWEEN ONCE-WEEKLY AND TWICE-WEEKLY GROUPS FOR PAIN REDUCTION [-2.1 (95% CI -2.9, -1.3) VERSUS -2.4 (95% CI -3.1, -1.8), P = 0.62] OR BACK-RELATED FUNCTION [-5.1 (95% CI -7.0, -3.2) VERSUS -4.9 (95% CI -6.5, -3.3), P = 0.83]. CONCLUSIONS. TWELVE WEEKS OF ONCE-WEEKLY OR TWICE-WEEKLY YOGA CLASSES WERE SIMILARLY EFFECTIVE FOR PREDOMINANTLY LOW INCOME MINORITY ADULTS WITH MODERATE TO SEVERE CHRONIC LOW BACK PAIN. THIS TRIAL IS REGISTERED WITH CLINICALTRIALS.GOV NCT01761617.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
7 1573  45 MANAGING KNEE OSTEOARTHRITIS WITH YOGA OR AEROBIC/STRENGTHENING EXERCISE PROGRAMS IN OLDER ADULTS: A PILOT RANDOMIZED CONTROLLED TRIAL. ALTHOUGH EXERCISE IS OFTEN RECOMMENDED FOR MANAGING OSTEOARTHRITIS (OA), LIMITED EVIDENCE-BASED EXERCISE OPTIONS ARE AVAILABLE FOR OLDER ADULTS WITH OA. THIS STUDY COMPARED THE EFFECTS OF HATHA YOGA (HY) AND AEROBIC/STRENGTHENING EXERCISES (ASE) ON KNEE OA. RANDOMIZED CONTROLLED TRIAL WITH THREE ARMS DESIGN WAS USED: HY, ASE, AND EDUCATION CONTROL. BOTH HY AND ASE GROUPS INVOLVED 8 WEEKLY 45-MIN GROUP CLASSES WITH 2-4 DAYS/WEEK HOME PRACTICE SESSIONS. CONTROL GROUP RECEIVED OA EDUCATION BROCHURES AND WEEKLY PHONE CALLS FROM STUDY STAFF. STANDARDIZED INSTRUMENTS WERE USED TO MEASURE OA SYMPTOMS, PHYSICAL FUNCTION, MOOD, SPIRITUAL HEALTH, FEAR OF FALLING, AND QUALITY OF LIFE AT BASELINE, 4 AND 8 WEEKS. HY/ASE ADHERENCES WERE ASSESSED WEEKLY USING CLASS ATTENDANCE RECORDS AND HOME PRACTICE VIDEO RECORDINGS. PRIMARY ANALYSIS OF THE DIFFERENCE IN THE CHANGE FROM BASELINE WAS BASED ON INTENT-TO-TREAT AND ADJUSTED FOR BASELINE VALUES. EIGHT-THREE ADULTS WITH SYMPTOMATIC KNEE OA COMPLETED THE STUDY (84% FEMALE; MEAN AGE 71.6 +/- 8.0 YEARS; MEAN BMI 29.0 +/- 7.0 KG/M(2)). RETENTION RATE WAS 82%. COMPARED TO THE ASE GROUP AT 8 WEEKS, PARTICIPANTS IN THE HY GROUP HAD A SIGNIFICANT IMPROVEMENT FROM BASELINE IN PERCEPTION OF OA SYMPTOMS (-9.6 [95% CI -15.3, -4]; P = .001), ANXIETY (-1.4 [95% CI -2.7, -0]; P = .04), AND FEAR OF FALLING (-4.6 [-7.5, -1.7]; P = .002). THERE WERE NO DIFFERENCES IN CLASS/HOME PRACTICE ADHERENCE BETWEEN HY AND ASE. THREE NON-SERIOUS ADVERSE EVENTS WERE REPORTED FROM THE ASE GROUP. BOTH HY AND ASE IMPROVED SYMPTOMS AND FUNCTION BUT HY MAY HAVE SUPERIOR BENEFITS FOR OLDER ADULTS WITH KNEE OA. TRIAL REGISTRATION THE FULL TRIAL PROTOCOL IS AVAILABLE AT CLINICALTRIALS.GOV (NCT02525341).	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
8  445  25 CHAIR YOGA: FEASIBILITY AND SUSTAINABILITY STUDY WITH OLDER COMMUNITY-DWELLING ADULTS WITH OSTEOARTHRITIS. THIS STUDY MEASURED THE FEASIBILITY OF COMPLETING A RANDOMIZED CONTROL TRIAL ON AN 8-WEEK SEATED YOGA PROGRAM FOR OLDER ADULTS WITH OSTEOARTHRITIS. PART OF THE FEASIBILITY OF THIS PROGRAM WAS TO DETERMINE WHETHER PARTICIPANTS WOULD CONTINUE THE YOGA PRACTICE AT HOME USING A GUIDE BOOK AFTER THE 8-WEEK PROGRAM. FINDINGS DEMONSTRATED THAT ONCE PARTICIPANTS WERE NOT IN A GROUP SETTING FOR THE YOGA, THEY DID NOT CONTINUE WITH YOGA PRACTICE. THIS OUTCOME DEMONSTRATES THE NEED FOR GROUP PROGRAMS FOR OLDER ADULTS TO PROMOTE ADHERENCE TO MOVEMENT-BASED PROGRAMS. (TRIAL REGISTRATION: CLINICALTRIALS.GOV: NCT02113410).	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
9   34  46 A 12-WEEK IYENGAR YOGA PROGRAM IMPROVED BALANCE AND MOBILITY IN OLDER COMMUNITY-DWELLING PEOPLE: A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: EXERCISE THAT CHALLENGES BALANCE CAN IMPROVE MOBILITY AND PREVENT FALLS IN OLDER ADULTS. YOGA AS A PHYSICAL ACTIVITY OPTION FOR OLDER ADULTS IS NOT WELL STUDIED. THIS TRIAL EVALUATED THE FEASIBILITY AND EFFECT OF A 12-WEEK IYENGAR YOGA PROGRAM ON BALANCE AND MOBILITY IN OLDER PEOPLE. METHODS: WE CONDUCTED A BLINDED, PILOT RANDOMIZED CONTROLLED TRIAL WITH INTENTION-TO-TREAT ANALYSIS. PARTICIPANTS WERE 54 COMMUNITY DWELLERS (MEAN AGE 68 YEARS, SD 7.1) NOT CURRENTLY PARTICIPATING IN YOGA OR TAI CHI. THE INTERVENTION GROUP (N = 27) PARTICIPATED IN A 12-WEEK, TWICE-WEEKLY YOGA PROGRAM FOCUSED ON STANDING POSTURES AND RECEIVED A FALL PREVENTION EDUCATION BOOKLET. THE CONTROL GROUP (N = 27) RECEIVED THE EDUCATION BOOKLET ONLY. PRIMARY OUTCOME WAS STANDING BALANCE COMPONENT OF THE SHORT PHYSICAL PERFORMANCE BATTERY WITH ADDITION OF ONE-LEGGED STANCE TIME (STANDING BALANCE). SECONDARY OUTCOMES WERE THE TIMED SIT-TO-STAND TEST, TIMED 4-M WALK, ONE-LEGGED STAND WITH EYES CLOSED, AND SHORT FALLS EFFICACY SCALE-INTERNATIONAL. FEASIBILITY WAS MEASURED BY RECORDING CLASS ATTENDANCE AND ADVERSE EVENTS. RESULTS: FIFTY-TWO PARTICIPANTS COMPLETED FOLLOW-UP ASSESSMENTS. THE INTERVENTION GROUP SIGNIFICANTLY IMPROVED COMPARED WITH CONTROL GROUP ON STANDING BALANCE (MEAN DIFFERENCE = 1.52 SECONDS, 95% CI 0.10-2.96, P = .04), SIT-TO-STAND TEST (MEAN DIFFERENCE = -3.43 SECONDS, 95% CI -5.23 TO -1.64, P < .001), 4-M WALK (MEAN DIFFERENCE = -0.50 SECONDS, 95% CI -0.72 TO -0.28, P < .001), AND ONE-LEGGED STAND WITH EYES CLOSED (MEAN DIFFERENCE = 1.93 SECONDS, 95% CI 0.40-3.46, P = .02). AVERAGE CLASS ATTENDANCE WAS 20 OF 24 CLASSES (83%). NO SERIOUS ADVERSE EVENTS OCCURRED. CONCLUSIONS: THIS TRIAL DEMONSTRATES THE BALANCE AND MOBILITY-RELATED BENEFITS AND FEASIBILITY OF IYENGAR YOGA FOR OLDER PEOPLE. THE FALL PREVENTION EFFECT OF IYENGAR YOGA WARRANTS FURTHER INVESTIGATION.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
10 1133  45 EFFICACY OF YOGA FOR VASOMOTOR SYMPTOMS: A RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: THIS STUDY AIMS TO DETERMINE THE EFFICACY OF YOGA IN ALLEVIATING VASOMOTOR SYMPTOMS (VMS) FREQUENCY AND BOTHER. METHODS: THIS STUDY WAS A THREE-BY-TWO FACTORIAL, RANDOMIZED CONTROLLED TRIAL. ELIGIBLE WOMEN WERE RANDOMIZED TO YOGA (N = 107), EXERCISE (N = 106), OR USUAL ACTIVITY (N = 142), AND WERE SIMULTANEOUSLY RANDOMIZED TO A DOUBLE-BLIND COMPARISON OF OMEGA-3 FATTY ACID (N = 177) OR PLACEBO (N = 178) CAPSULES. YOGA INTERVENTION CONSISTED OF 12 WEEKLY 90-MINUTE YOGA CLASSES WITH DAILY HOME PRACTICE. PRIMARY OUTCOMES WERE VMS FREQUENCY AND BOTHER ASSESSED BY DAILY DIARIES AT BASELINE, 6 WEEKS, AND 12 WEEKS. SECONDARY OUTCOMES INCLUDED INSOMNIA SYMPTOMS (INSOMNIA SEVERITY INDEX) AT BASELINE AND 12 WEEKS. RESULTS: AMONG 249 RANDOMIZED WOMEN, 237 (95%) COMPLETED 12-WEEK ASSESSMENTS. THE MEAN BASELINE VMS FREQUENCY WAS 7.4 PER DAY (95% CI, 6.6 TO 8.1) IN THE YOGA GROUP AND 8.0 PER DAY (95% CI, 7.3 TO 8.7) IN THE USUAL ACTIVITY GROUP. INTENT-TO-TREAT ANALYSES INCLUDED ALL PARTICIPANTS WITH RESPONSE DATA (N = 237). THERE WAS NO DIFFERENCE BETWEEN INTERVENTION GROUPS IN THE CHANGE IN VMS FREQUENCY FROM BASELINE TO 6 AND 12 WEEKS (MEAN DIFFERENCE [YOGA--USUAL ACTIVITY] FROM BASELINE AT 6 WK, -0.3 [95% CI, -1.1 TO 0.5]; MEAN DIFFERENCE [YOGA--USUAL ACTIVITY] FROM BASELINE AT 12 WK, -0.3 [95% CI, -1.2 TO 0.6]; P = 0.119 ACROSS BOTH TIME POINTS). RESULTS WERE SIMILAR FOR VMS BOTHER. AT WEEK 12, YOGA WAS ASSOCIATED WITH AN IMPROVEMENT IN INSOMNIA SYMPTOMS (MEAN DIFFERENCE [YOGA - USUAL ACTIVITY] IN THE CHANGE IN INSOMNIA SEVERITY INDEX, 1.3 [95% CI, -2.5 TO -0.1]; P = 0.007). CONCLUSIONS: AMONG HEALTHY WOMEN, 12 WEEKS OF YOGA CLASS PLUS HOME PRACTICE, COMPARED WITH USUAL ACTIVITY, DO NOT IMPROVE VMS FREQUENCY OR BOTHER BUT REDUCE INSOMNIA SYMPTOMS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
11 2090  24 THE EFFECT OF SIT 'N' FIT CHAIR YOGA AMONG COMMUNITY-DWELLING OLDER ADULTS WITH OSTEOARTHRITIS. THE STUDY MEASURED EFFECTS OF SIT 'N' FIT CHAIR YOGA ON PAIN AND PHYSICAL AND PSYCHOLOGICAL FUNCTIONING. A QUASI-EXPERIMENTAL RESEARCH DESIGN INCLUDED A YOGA INTERVENTION GROUP AND AN ATTENTION CONTROL GROUP. THERE WAS GREATER IMPROVEMENT IN DEPRESSION AND LIFE SATISFACTION IN THE YOGA GROUP THAN IN THE CONTROL GROUP.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
12 2077  26 THE EFFECT OF CHAIR YOGA IN OLDER ADULTS WITH MODERATE AND SEVERE ALZHEIMER'S DISEASE. USING A QUASI-EXPERIMENTAL SINGLE-GROUP DESIGN, THIS STUDY EXAMINED THE FEASIBILITY OF OLDER ADULTS WITH ALZHEIMER'S DISEASE (AD)-TYPE DEMENTIA TO COMPLETE THE SIT 'N' FIT CHAIR YOGA PROGRAM. PHYSICAL FUNCTION OF PARTICIPANTS WHO COMPLETED THE PROGRAM WAS MEASURED. THE NINE OLDER ADULTS WITH AD (MEAN AGE = 83) PARTICIPATED IN THE 8-WEEK SIT 'N' FIT CHAIR YOGA PROGRAM. TO MEASURE PHYSICAL FUNCTION, THE SIX-MINUTE WALK TEST, THE GAIT SPEED TEST, AND THE BERG BALANCE SCALE WERE ADMINISTERED AT PRE-INTERVENTION, 4 WEEKS, 8 WEEKS, AND 1 MONTH AFTER PROGRAM COMPLETION. ALL PARTICIPANTS COMPLETED THE PROGRAM. POSITIVE CHANGES WERE SEEN ACROSS ALL PHYSICAL MEASURES. FURTHER STUDY, USING A LARGER SAMPLE AND INCLUDING A CONTROL GROUP, IS NEEDED TO FULLY DETERMINE THE EFFECT OF THE SIT 'N' FIT CHAIR YOGA PROGRAM ON OLDER ADULTS WITH MODERATE TO SEVERE AD.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
13  521  47 COMPARING YOGA, EXERCISE, AND A SELF-CARE BOOK FOR CHRONIC LOW BACK PAIN: A RANDOMIZED, CONTROLLED TRIAL. BACKGROUND: CHRONIC LOW BACK PAIN IS A COMMON PROBLEM THAT HAS ONLY MODESTLY EFFECTIVE TREATMENT OPTIONS. OBJECTIVE: TO DETERMINE WHETHER YOGA IS MORE EFFECTIVE THAN CONVENTIONAL THERAPEUTIC EXERCISE OR A SELF-CARE BOOK FOR PATIENTS WITH CHRONIC LOW BACK PAIN. DESIGN: RANDOMIZED, CONTROLLED TRIAL. SETTING: A NONPROFIT, INTEGRATED HEALTH CARE SYSTEM. PATIENTS: 101 ADULTS WITH CHRONIC LOW BACK PAIN. INTERVENTION: 12-WEEK SESSIONS OF YOGA OR CONVENTIONAL THERAPEUTIC EXERCISE CLASSES OR A SELF-CARE BOOK. MEASUREMENTS: PRIMARY OUTCOMES WERE BACK-RELATED FUNCTIONAL STATUS (MODIFIED 24-POINT ROLAND DISABILITY SCALE) AND "BOTHERSOMENESS" OF PAIN (11-POINT NUMERICAL SCALE). THE PRIMARY TIME POINT WAS 12 WEEKS. CLINICALLY SIGNIFICANT CHANGE WAS CONSIDERED TO BE 2.5 POINTS ON THE FUNCTIONAL STATUS SCALE AND 1.5 POINTS ON THE BOTHERSOMENESS SCALE. SECONDARY OUTCOMES WERE DAYS OF RESTRICTED ACTIVITY, GENERAL HEALTH STATUS, AND MEDICATION USE. RESULTS: AFTER ADJUSTMENT FOR BASELINE VALUES, BACK-RELATED FUNCTION IN THE YOGA GROUP WAS SUPERIOR TO THE BOOK AND EXERCISE GROUPS AT 12 WEEKS (YOGA VS. BOOK: MEAN DIFFERENCE, -3.4 [95% CI, -5.1 TO - 1.6] [P < 0.001]; YOGA VS. EXERCISE: MEAN DIFFERENCE, -1.8 [CI, -3.5 TO - 0.1] [P = 0.034]). NO SIGNIFICANT DIFFERENCES IN SYMPTOM BOTHERSOMENESS WERE FOUND BETWEEN ANY 2 GROUPS AT 12 WEEKS; AT 26 WEEKS, THE YOGA GROUP WAS SUPERIOR TO THE BOOK GROUP WITH RESPECT TO THIS MEASURE (MEAN DIFFERENCE, -2.2 [CI, -3.2 TO - 1.2]; P < 0.001). AT 26 WEEKS, BACK-RELATED FUNCTION IN THE YOGA GROUP WAS SUPERIOR TO THE BOOK GROUP (MEAN DIFFERENCE, -3.6 [CI, -5.4 TO - 1.8]; P < 0.001). LIMITATIONS: PARTICIPANTS IN THIS STUDY WERE FOLLOWED FOR ONLY 26 WEEKS AFTER RANDOMIZATION. ONLY 1 INSTRUCTOR DELIVERED EACH INTERVENTION. CONCLUSIONS: YOGA WAS MORE EFFECTIVE THAN A SELF-CARE BOOK FOR IMPROVING FUNCTION AND REDUCING CHRONIC LOW BACK PAIN, AND THE BENEFITS PERSISTED FOR AT LEAST SEVERAL MONTHS.	2005	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
14 1113  50 EFFICACY OF A BIOMECHANICALLY-BASED YOGA EXERCISE PROGRAM IN KNEE OSTEOARTHRITIS: A RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: CERTAIN EXERCISES COULD OVERLOAD THE OSTEOARTHRITIC KNEE. WE DEVELOPED AN EXERCISE PROGRAM FROM YOGA POSTURES WITH A MINIMAL KNEE ADDUCTION MOMENT FOR KNEE OSTEOARTHRITIS. THE PURPOSE WAS TO COMPARE THE EFFECTIVENESS OF THIS BIOMECHANICALLY-BASED YOGA EXERCISE (YE), WITH TRADITIONAL EXERCISE (TE), AND A NO-EXERCISE ATTENTION-EQUIVALENT CONTROL (NE) FOR IMPROVING PAIN, SELF-REPORTED PHYSICAL FUNCTION AND MOBILITY PERFORMANCE IN WOMEN WITH KNEE OSTEOARTHRITIS. DESIGN: SINGLE-BLIND, THREE-ARM RANDOMIZED CONTROLLED TRIAL. SETTING: COMMUNITY IN SOUTHWESTERN ONTARIO, CANADA. PARTICIPANTS: A CONVENIENCE SAMPLE OF 31 WOMEN WITH SYMPTOMATIC KNEE OSTEOARTHRITIS WAS RECRUITED THROUGH RHEUMATOLOGY, ORTHOPAEDIC AND PHYSIOTHERAPY CLINICS, NEWSPAPERS AND WORD-OF-MOUTH. INTERVENTIONS: PARTICIPANTS WERE STRATIFIED BY DISEASE SEVERITY AND RANDOMLY ALLOCATED TO ONE OF THREE 12-WEEK, SUPERVISED INTERVENTIONS. YE INCLUDED BIOMECHANICALLY-BASED YOGA EXERCISES; TE INCLUDED TRADITIONAL LEG STRENGTHENING ON MACHINES; AND NE INCLUDED MEDITATION WITH NO EXERCISE. PARTICIPANTS WERE ASKED TO ATTEND THREE 1-HOUR GROUP CLASSES/SESSIONS EACH WEEK. MEASUREMENTS: PRIMARY OUTCOMES WERE PAIN, SELF-REPORTED PHYSICAL FUNCTION AND MOBILITY PERFORMANCE. SECONDARY OUTCOMES WERE KNEE STRENGTH, DEPRESSION, AND HEALTH-RELATED QUALITY OF LIFE. ALL WERE ASSESSED BY A BLINDED ASSESSOR AT BASELINE AND IMMEDIATELY FOLLOWING THE INTERVENTION. RESULTS: THE YE GROUP DEMONSTRATED GREATER IMPROVEMENTS IN KOOS PAIN (MEAN DIFFERENCE OF 22.9 [95% CI, 6.9 TO 38.8; P = 0.003]), INTERMITTENT PAIN (MEAN DIFFERENCE OF -19.6 [95% CI, -34.8 TO -4.4; P = 0.009]) AND SELF-REPORTED PHYSICAL FUNCTION (MEAN DIFFERENCE OF 17.2 [95% CI, 5.2 TO 29.2; P = 0.003]) COMPARED TO NE. IMPROVEMENTS IN THESE OUTCOMES WERE SIMILAR BETWEEN YE AND TE. HOWEVER, TE DEMONSTRATED A GREATER IMPROVEMENT IN KNEE FLEXOR STRENGTH COMPARED TO YE (MEAN DIFFERENCE OF 0.1 [95% CI, 0.1 TO 0.2]. IMPROVEMENTS FROM BASELINE TO FOLLOW-UP WERE PRESENT IN QUALITY OF LIFE SCORE FOR YE AND KNEE FLEXOR STRENGTH FOR TE, WHILE BOTH ALSO DEMONSTRATED IMPROVEMENTS IN MOBILITY. NO IMPROVEMENT IN ANY OUTCOME WAS PRESENT IN NE. CONCLUSIONS: THE BIOMECHANICALLY-BASED YOGA EXERCISE PROGRAM PRODUCED CLINICALLY MEANINGFUL IMPROVEMENTS IN PAIN, SELF-REPORTED PHYSICAL FUNCTION AND MOBILITY IN WOMEN WITH CLINICAL KNEE OA COMPARED TO NO EXERCISE. WHILE NOT STATISTICALLY SIGNIFICANT, IMPROVEMENTS IN THESE OUTCOMES WERE LARGER THAN THOSE ELICITED FROM THE TRADITIONAL EXERCISE-BASED PROGRAM. THOUGH THIS MAY SUGGEST THAT THE YOGA PROGRAM MAY BE MORE EFFICACIOUS FOR KNEE OA, FUTURE RESEARCH STUDYING A LARGER SAMPLE IS REQUIRED. TRIAL REGISTRATION: CLINICALTRIALS.GOV (NCT02370667).	2018	
                                                                                                                                                                                                                                                                                          
15 2836  44 YOGA'S IMPACT ON INFLAMMATION, MOOD, AND FATIGUE IN BREAST CANCER SURVIVORS: A RANDOMIZED CONTROLLED TRIAL. PURPOSE: TO EVALUATE YOGA'S IMPACT ON INFLAMMATION, MOOD, AND FATIGUE. PATIENTS AND METHODS: A RANDOMIZED CONTROLLED 3-MONTH TRIAL WAS CONDUCTED WITH TWO POST-TREATMENT ASSESSMENTS OF 200 BREAST CANCER SURVIVORS ASSIGNED TO EITHER 12 WEEKS OF 90-MINUTE TWICE PER WEEK HATHA YOGA CLASSES OR A WAIT-LIST CONTROL. THE MAIN OUTCOME MEASURES WERE LIPOPOLYSACCHARIDE-STIMULATED PRODUCTION OF PROINFLAMMATORY CYTOKINES INTERLEUKIN-6 (IL-6), TUMOR NECROSIS FACTOR ALPHA (TNF-ALPHA), AND INTERLEUKIN-1BETA (IL-1BETA), AND SCORES ON THE MULTIDIMENSIONAL FATIGUE SYMPTOM INVENTORY-SHORT FORM (MFSI-SF), THE VITALITY SCALE FROM THE MEDICAL OUTCOMES STUDY 36-ITEM SHORT FORM (SF-36), AND THE CENTER FOR EPIDEMIOLOGICAL STUDIES-DEPRESSION (CES-D) SCALE. RESULTS: IMMEDIATELY POST-TREATMENT, FATIGUE WAS NOT LOWER (P > .05) BUT VITALITY WAS HIGHER (P = .01) IN THE YOGA GROUP COMPARED WITH THE CONTROL GROUP. AT 3 MONTHS POST-TREATMENT, FATIGUE WAS LOWER IN THE YOGA GROUP (P = .002), VITALITY WAS HIGHER (P = .01), AND IL-6 (P = .027), TNF-ALPHA (P = .027), AND IL-1BETA (P = .037) WERE LOWER FOR YOGA PARTICIPANTS COMPARED WITH THE CONTROL GROUP. GROUPS DID NOT DIFFER ON DEPRESSION AT EITHER TIME (P > .2). PLANNED SECONDARY ANALYSES SHOWED THAT THE FREQUENCY OF YOGA PRACTICE HAD STRONGER ASSOCIATIONS WITH FATIGUE AT BOTH POST-TREATMENT VISITS (P = .019; P < .001), AS WELL AS VITALITY (P = .016; P = .0045), BUT NOT DEPRESSION (P > .05) THAN SIMPLE GROUP ASSIGNMENT; MORE FREQUENT PRACTICE PRODUCED LARGER CHANGES. AT 3 MONTHS POST-TREATMENT, INCREASING YOGA PRACTICE ALSO LED TO A DECREASE IN IL-6 (P = .01) AND IL-1BETA (P = .03) PRODUCTION BUT NOT IN TNF-ALPHA PRODUCTION (P > .05). CONCLUSION: CHRONIC INFLAMMATION MAY FUEL DECLINES IN PHYSICAL FUNCTION LEADING TO FRAILTY AND DISABILITY. IF YOGA DAMPENS OR LIMITS BOTH FATIGUE AND INFLAMMATION, THEN REGULAR PRACTICE COULD HAVE SUBSTANTIAL HEALTH BENEFITS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
16 1021  36 EFFECTS OF YOGA AND AEROBIC EXERCISE ON WELLBEING IN PHYSICALLY INACTIVE OLDER ADULTS: RANDOMIZED CONTROLLED TRIAL (FITFORAGE). OBJECTIVE: TO COMPARE THE EFFECTS OF YOGA AND AEROBIC EXERCISE (AE) ON WELLBEING IN PHYSICALLY INACTIVE, BUT OTHERWISE HEALTHY OLDER ADULTS. A SECONDARY OBJECTIVE WAS TO ASSESS AND COMPARE THE FREQUENCY OF ADVERSE EVENTS ASSOCIATED WITH YOGA AND AE. DESIGN: TWELVE-WEEK, THREE-GROUP, PARALLEL RANDOMIZED CONTROLLED TRIAL WITH BLINDED FOLLOW-UP ASSESSMENT. INTERVENTIONS: PARTICIPANTS WERE SUPPORTED TO COMPLETE >/= 3 HATHA YOGA CLASSES/WEEK OR >/= 3 AE SESSIONS/WEEK. A WAIT-LIST CONTROL (WLC) GROUP CONTINUED USUAL DAILY ACTIVITIES. MAIN OUTCOME MEASURE: CHANGE IN WELLBEING, ASSESSED USING THE SATISFACTION WITH LIFE SCALE (SWLS) AND LIFE SATISFACTION INDEX-Z (LSI),AT BASELINE AND AT 12-WEEK FOLLOW UP. RESULTS: IN TOTAL, 82 ADULTS (MEAN AGE 72.5 YEARS, RANGE 65-85, 77% FEMALE) WERE RECRUITED. OF THESE, 27 WERE RANDOMIZED TO YOGA, 29 TO AEROBIC EXERCISE AND 26 TO WAIT-LIST CONTROL. MEDIUM-MAGNITUDE TREATMENT EFFECTS (HEDGES' G) WERE SEEN FOR YOGA VERSUS WLC AND AE VERSUS WLC(SWLS, G = 0.65 AND 0.56; LSI, G = 0.54 AND 0.54, RESPECTIVELY). IN PER-PROTOCOL ANALYSES, LARGER EFFECT SIZES WERE FOUND (SWLS, G = 0.72 AND 0.66; LSI, G = 0.76 AND 0.76, RESPECTIVELY). ADVERSE EVENTS WERE LESS FREQUENT IN THE YOGA GROUP (6/27; 22%) COMPARED TO AE (10/27; 37%). CONCLUSIONS: AMONG PHYSICALLY INACTIVE OLDER ADULTS, PARTICIPATION IN YOGA OR AE WAS ASSOCIATED WITH BENEFICIAL EFFECTS ON SUBJECTIVE WELLBEING WHEN COMPARED TO A NON-ACTIVE CONTROL GROUP. YOGA WAS ASSOCIATED WITH FEWER INJURIES AND MAY BE ESPECIALLY SUITABLE FOR OLDER ADULTS (DRKS 00015093).	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
17 2134  35 THE EFFECTS OF A THERAPEUTIC YOGA PROGRAM ON POSTURAL CONTROL, MOBILITY, AND GAIT SPEED IN COMMUNITY-DWELLING OLDER ADULTS. OBJECTIVE: TO EXAMINE THE EFFECTS OF A 12-WEEK THERAPEUTIC YOGA PROGRAM ON GAIT SPEED, POSTURAL CONTROL, AND MOBILITY IN COMMUNITY-DWELLING OLDER ADULTS. DESIGN: QUASI-EXPERIMENTAL STUDY WITH A PRETEST/POST-TEST DESIGN. RESEARCHERS EVALUATED CHANGES OVER TIME (PRETEST TO POST-TEST) IN ALL OUTCOME MEASURES. PAIRED T-TESTS WERE USED TO ANALYZE NORMAL AND FAST GAIT SPEED, TIMED UP AND GO TEST, AND TIMED UP AND GO DUAL TASK. WILCOXON SIGNED-RANK TEST WAS USED TO EVALUATE SCORES FOR THE MINI-BESTEST (MBT). SETTING: YOGA CLASSES WERE PERFORMED AT A LOCAL SENIOR CENTER. BLIND EXAMINERS WHO WERE PREVIOUSLY TRAINED IN THE OUTCOME MEASURES PERFORMED ALL PRETESTS AND POST-TESTS AT THE SITE. PARTICIPANTS: THIRTEEN ADULTS (12 WOMEN AND 1 MAN, WITH A MEAN AGE+/-STANDARD DEVIATION OF 72+/-6.9 YEARS) COMPLETED THE STUDY. RESEARCH PARTICIPANTS HAD MINIMAL TO NO YOGA EXPERIENCE. INTERVENTIONS: A 12-WEEK, 60-MINUTE, BIWEEKLY KRIPALU YOGA CLASS DESIGNED SPECIFICALLY FOR COMMUNITY-DWELLING OLDER ADULTS. OUTCOME MEASURES: POSTURAL CONTROL (MBT), MOBILITY (TIMED UP AND GO TEST), AND GAIT SPEED (NORMAL AND FAST) WERE ASSESSED. RESULTS: ALL 13 PARTICIPANTS ATTENDED AT LEAST 19 OF THE 24 CLASSES (80% ATTENDANCE). STATISTICALLY SIGNIFICANT IMPROVEMENTS WERE SEEN IN THE MBT (P=0.039), NORMAL GAIT SPEED (P=0.015), FAST GAIT SPEED (P=0.001), TIMED UP AND GO TEST (P=0.045), AND TIMED UP AND GO DUAL-TASK (P=0.05). CONCLUSIONS: IMPROVEMENTS IN POSTURAL CONTROL AND MOBILITY AS MEASURED BY THE MBT AND TIMED UP AND GO GAIT AS MEASURED BY FAST GAIT SPEED INDICATE THAT RESEARCH PARTICIPANTS BENEFITTED FROM THE THERAPEUTIC YOGA INTERVENTION. THE YOGA PROGRAM DESIGNED FOR THIS STUDY INCLUDED ACTIVITIES IN STANDING, SITTING, AND LYING ON THE FLOOR AND MAY BE EFFECTIVE IN IMPROVING MOBILITY, POSTURAL CONTROL, AND GAIT SPEED IN COMMUNITY-DWELLING OLDER ADULTS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
18  444  26 CHAIR YOGA: BENEFITS FOR COMMUNITY-DWELLING OLDER ADULTS WITH OSTEOARTHRITIS. THE AIM OF THIS PILOT STUDY WAS TO EXAMINE WHETHER CHAIR YOGA WAS EFFECTIVE IN REDUCING PAIN LEVEL AND IMPROVING PHYSICAL FUNCTION AND EMOTIONAL WELL-BEING IN A SAMPLE OF COMMUNITY-DWELLING OLDER ADULTS WITH OSTEOARTHRITIS. ONE-WAY REPEATED MEASURES ANALYSIS OF VARIANCE WAS PERFORMED TO EXAMINE THE EFFECTIVENESS OF CHAIR YOGA AT BASELINE, MIDPOINT (4 WEEKS), AND END OF THE INTERVENTION (8 WEEKS). ALTHOUGH CHAIR YOGA WAS EFFECTIVE IN IMPROVING PHYSICAL FUNCTION AND REDUCING STIFFNESS IN OLDER ADULTS WITH OSTEOARTHRITIS, IT WAS NOT EFFECTIVE IN REDUCING PAIN LEVEL OR IMPROVING DEPRESSIVE SYMPTOMS. FUTURE RESEARCH PLANNED BY THIS TEAM WILL USE RIGOROUS STUDY METHODS, INCLUDING LARGER SAMPLES, RANDOMIZED CONTROLLED TRIALS, AND FOLLOW UP FOR MONITORING HOME PRACTICE AFTER THE INTERVENTIONS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
19 1007  51 EFFECTS OF MINDFULNESS YOGA VS STRETCHING AND RESISTANCE TRAINING EXERCISES ON ANXIETY AND DEPRESSION FOR PEOPLE WITH PARKINSON DISEASE: A RANDOMIZED CLINICAL TRIAL. IMPORTANCE: CLINICAL PRACTICE GUIDELINES SUPPORT EXERCISE FOR PATIENTS WITH PARKINSON DISEASE (PD), BUT TO OUR KNOWLEDGE, NO RANDOMIZED CLINICAL TRIALS HAVE TESTED WHETHER YOGA IS SUPERIOR TO CONVENTIONAL PHYSICAL EXERCISES FOR STRESS AND SYMPTOM MANAGEMENT. OBJECTIVE: TO COMPARE THE EFFECTS OF A MINDFULNESS YOGA PROGRAM VS STRETCHING AND RESISTANCE TRAINING EXERCISE (SRTE) ON PSYCHOLOGICAL DISTRESS, PHYSICAL HEALTH, SPIRITUAL WELL-BEING, AND HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN PATIENTS WITH MILD-TO-MODERATE PD. DESIGN, SETTING, AND PARTICIPANTS: AN ASSESSOR-MASKED, RANDOMIZED CLINICAL TRIAL USING THE INTENTION-TO-TREAT PRINCIPLE WAS CONDUCTED AT 4 COMMUNITY REHABILITATION CENTERS IN HONG KONG BETWEEN DECEMBER 1, 2016, AND MAY 31, 2017. A TOTAL OF 187 ADULTS (AGED >/=18 YEARS) WITH A CLINICAL DIAGNOSIS OF IDIOPATHIC PD WHO WERE ABLE TO STAND UNAIDED AND WALK WITH OR WITHOUT AN ASSISTIVE DEVICE WERE ENROLLED VIA CONVENIENCE SAMPLING. ELIGIBLE PARTICIPANTS WERE RANDOMIZED 1:1 TO MINDFULNESS YOGA OR SRTE. INTERVENTIONS: MINDFULNESS YOGA WAS DELIVERED IN 90-MINUTE GROUPS AND SRTE WERE DELIVERED IN 60-MINUTE GROUPS FOR 8 WEEKS. MAIN OUTCOMES AND MEASURES: PRIMARY OUTCOMES INCLUDED ANXIETY AND DEPRESSIVE SYMPTOMS ASSESSED USING THE HOSPITAL ANXIETY AND DEPRESSION SCALE. SECONDARY OUTCOMES INCLUDED SEVERITY OF MOTOR SYMPTOMS (MOVEMENT DISORDER SOCIETY UNIFIED PARKINSON'S DISEASE RATING SCALE [MDS-UPDRS], PART III MOTOR SCORE), MOBILITY, SPIRITUAL WELL-BEING IN TERMS OF PERCEIVED HARDSHIP AND EQUANIMITY, AND HRQOL. ASSESSMENTS WERE DONE AT BASELINE, 8 WEEKS (T1), AND 20 WEEKS (T2). RESULTS: THE 138 PARTICIPANTS INCLUDED 65 MEN (47.1%) WITH A MEAN (SD) AGE OF 63.7 (8.7) YEARS AND A MEAN (SD) MDS-UPDRS SCORE OF 33.3 (15.3). GENERALIZED ESTIMATING EQUATION ANALYSES REVEALED THAT THE YOGA GROUP HAD SIGNIFICANTLY BETTER IMPROVEMENT IN OUTCOMES THAN THE SRTE GROUP, PARTICULARLY FOR ANXIETY (TIME-BY-GROUP INTERACTION, T1: BETA, -1.79 [95% CI, -2.85 TO -0.69; P = .001]; T2: BETA, -2.05 [95% CI, -3.02 TO -1.08; P < .001]), DEPRESSION (T1: BETA, -2.75 [95% CI, -3.17 TO -1.35; P < .001]); T2: BETA, -2.75 [95% CI, -3.71 TO -1.79; P < .001]), PERCEIVED HARDSHIP (T1: BETA, -0.92 [95% CI, -1.25 TO -0.61; P < .001]; T2: BETA, -0.76 [95% CI, -1.12 TO -0.40; P < .001]), PERCEIVED EQUANIMITY (T1: BETA, 1.11 [95% CI, 0.79-1.42; P < .001]; T2: BETA, 1.19 [95% CI, 0.82-1.56; P < .001]), AND DISEASE-SPECIFIC HRQOL (T1: BETA, -7.77 [95% CI, -11.61 TO -4.38; P < .001]; T2: BETA, -7.99 [95% CI, -11.61 TO -4.38; P < .001]). CONCLUSIONS AND RELEVANCE: AMONG PATIENTS WITH MILD-TO-MODERATE PD, THE MINDFULNESS YOGA PROGRAM WAS FOUND TO BE AS EFFECTIVE AS SRTE IN IMPROVING MOTOR DYSFUNCTION AND MOBILITY, WITH THE ADDITIONAL BENEFITS OF A REDUCTION IN ANXIETY AND DEPRESSIVE SYMPTOMS AND AN INCREASE IN SPIRITUAL WELL-BEING AND HRQOL. TRIAL REGISTRATION: CENTRE FOR CLINICAL RESEARCH AND BIOSTATISTICS IDENTIFIER: CUHK_CCRB00522.	2019	

20 1429  40 IMPROVEMENTS IN PSYCHOLOGICAL AND OCCUPATIONAL WELL-BEING IN A PRAGMATIC CONTROLLED TRIAL OF A YOGA-BASED PROGRAM FOR PROFESSIONALS. OBJECTIVE: THE PURPOSE OF THIS PRAGMATIC CONTROLLED TRIAL WAS TO EXAMINE CHANGES IN PSYCHOLOGICAL AND OCCUPATIONAL WELL-BEING IN PROFESSIONALS WHO ATTENDED A YOGA-BASED PROGRAM. SETTING: THE 5-DAY RISE (RESILIENCE, INTEGRATION, SELF-AWARENESS, ENGAGEMENT) PROGRAM WAS DELIVERED AT THE KRIPALU CENTER FOR YOGA & HEALTH. RISE INCLUDED 5 H PER DAY OF YOGA, MEDITATION, LECTURES, AND EXPERIENTIAL ACTIVITIES. SUBJECTS: ADULT PROFESSIONALS FROM EDUCATION, CORRECTIONS, AND SOCIAL SERVICE INSTITUTIONS WERE PRAGMATICALLY ASSIGNED TO THE RISE GROUP (N = 61) OR A WAITLIST CONTROL GROUP (N = 60). OUTCOME MEASURES: MEASURES OF PSYCHOLOGICAL AND OCCUPATIONAL WELL-BEING WERE COMPLETED BEFORE RISE (BASELINE), IMMEDIATELY AFTER RISE (POSTPROGRAM), AND 2 MONTHS AFTER RISE (FOLLOW-UP). ANALYSES OF COVARIANCE WERE CONDUCTED TO COMPARE CHANGE SCORES BETWEEN GROUPS. RESULTS: EIGHTY-TWO PARTICIPANTS (RISE N = 41, CONTROL N = 41) COMPLETED BASELINE AND POSTMEASURES AND WERE INCLUDED IN THE ANALYSIS, AND 57 (RISE N = 27, CONTROL N = 30) ALSO COMPLETED THE FOLLOW-UP. RELATIVE TO CONTROLS, THE RISE GROUP REPORTED IMPROVEMENTS IN STRESS (P = 0.001, R(2) = 0.51), RESILIENCE (P = 0.028, R(2) = 0.34), POSITIVE AFFECT (P = 0.001, R(2) = 0.52), NEGATIVE AFFECT (P = 0.001, R(2) = 0.52), MINDFULNESS (P = 0.021, R(2) = 0.13), AND JOB SATISFACTION (P = 0.034, R(2) = 0.08) FROM BASELINE TO POSTPROGRAM. FROM BASELINE TO FOLLOW-UP, COMPARED WITH CONTROLS THE RISE GROUP SHOWED IMPROVEMENTS IN STRESS (P = 0.001, R(2) = 0.33), RESILIENCE (P = 0.001, R(2) = 0.24), POSITIVE AFFECT (P = 0.006, R(2) = 0.49), NEGATIVE AFFECT (P = 0.043, R(2) = 0.32), MINDFULNESS (P = 0.001, R(2) = 0.28), EMPOWERMENT (P = 0.005, R(2) = 0.20), AND SELF-COMPASSION (P = 0.011, R(2) = 0.19). CONCLUSIONS: THE RISE PROGRAM WAS ASSOCIATED WITH IMPROVEMENTS IN PSYCHOLOGICAL AND OCCUPATIONAL WELL-BEING IMMEDIATELY AFTER AND 2 MONTHS AFTER THE PROGRAM. FUTURE RESEARCH IS NEEDED TO CONFIRM THESE RESULTS.	2019