1 2729 132 YOGA OF AWARENESS PROGRAM FOR MENOPAUSAL SYMPTOMS IN BREAST CANCER SURVIVORS: RESULTS FROM A RANDOMIZED TRIAL. GOAL OF WORK: BREAST CANCER SURVIVORS HAVE LIMITED OPTIONS FOR THE TREATMENT OF HOT FLASHES AND RELATED SYMPTOMS. FURTHER, THERAPIES WIDELY USED TO PREVENT RECURRENCE IN SURVIVORS, SUCH AS TAMOXIFEN, TEND TO INDUCE OR EXACERBATE MENOPAUSAL SYMPTOMS. THE AIM OF THIS PRELIMINARY, RANDOMIZED CONTROLLED TRIAL WAS TO EVALUATE THE EFFECTS OF A YOGA INTERVENTION ON MENOPAUSAL SYMPTOMS IN A SAMPLE OF SURVIVORS OF EARLY-STAGE BREAST CANCER (STAGES IA-IIB). MATERIALS AND METHODS: THIRTY-SEVEN DISEASE-FREE WOMEN EXPERIENCING HOT FLASHES WERE RANDOMIZED TO THE 8-WEEK YOGA OF AWARENESS PROGRAM (GENTLE YOGA POSES, MEDITATION, AND BREATHING EXERCISES) OR TO WAIT-LIST CONTROL. THE PRIMARY OUTCOME WAS DAILY REPORTS OF HOT FLASHES COLLECTED AT BASELINE, POSTTREATMENT, AND 3 MONTHS AFTER TREATMENT VIA AN INTERACTIVE TELEPHONE SYSTEM. DATA WERE ANALYZED BY INTENTION TO TREAT. MAIN RESULTS: AT POSTTREATMENT, WOMEN WHO RECEIVED THE YOGA PROGRAM SHOWED SIGNIFICANTLY GREATER IMPROVEMENTS RELATIVE TO THE CONTROL CONDITION IN HOT-FLASH FREQUENCY, SEVERITY, AND TOTAL SCORES AND IN LEVELS OF JOINT PAIN, FATIGUE, SLEEP DISTURBANCE, SYMPTOM-RELATED BOTHER, AND VIGOR. AT 3 MONTHS FOLLOW-UP, PATIENTS MAINTAINED THEIR TREATMENT GAINS IN HOT FLASHES, JOINT PAIN, FATIGUE, SYMPTOM-RELATED BOTHER, AND VIGOR AND SHOWED ADDITIONAL SIGNIFICANT GAINS IN NEGATIVE MOOD, RELAXATION, AND ACCEPTANCE. CONCLUSIONS: THIS PILOT STUDY PROVIDES PROMISING SUPPORT FOR THE BENEFICIAL EFFECTS OF A COMPREHENSIVE YOGA PROGRAM FOR HOT FLASHES AND OTHER MENOPAUSAL SYMPTOMS IN EARLY-STAGE BREAST CANCER SURVIVORS.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
2 1099  40 EFFECTS OF YOGA THERAPY ON POSTURAL STABILITY IN PATIENTS WITH SCHIZOPHRENIA-SPECTRUM DISORDERS: A SINGLE-BLIND RANDOMIZED CONTROLLED TRIAL. INTRODUCTION: POSTURAL INSTABILITY IS A SERIOUS CONCERN IN PATIENTS WITH SCHIZOPHRENIA-SPECTRUM DISORDERS SINCE IT IS EXPECTED TO INCREASE THE RISK OF FALLS THAT MAY LEAD TO FRACTURES. THE IMPACT OF YOGA THERAPY ON POSTURAL STABILITY HAS NOT BEEN INVESTIGATED. METHODS: IN THIS EIGHT-WEEK SINGLE-BLIND RANDOMIZED CONTROLLED STUDY WITH AN EIGHT-WEEK FOLLOW-UP, OUTPATIENTS WITH SCHIZOPHRENIA OR RELATED PSYCHOTIC DISORDER (ICD-10) WERE RANDOMLY ASSIGNED TO EITHER YOGA THERAPY OR A CONTROL GROUP. IN THE YOGA THERAPY GROUP, THE SUBJECTS RECEIVED WEEKLY SESSIONS OF 60-MIN YOGA THERAPY FOR EIGHT WEEKS IN ADDITION TO THEIR ONGOING TREATMENT. IN THE CONTROL GROUP, THE SUBJECTS RECEIVED A WEEKLY REGULAR DAY-CARE PROGRAM. THE ASSESSMENTS THAT WERE PERFORMED AT THE BASELINE AND ENDPOINT INCLUDED THE CLINICAL STABILOMETRIC PLATFORM (CSP), ANTEFLEXION IN STANDING. RESULTS: FORTY-NINE PATIENTS PARTICIPATED IN THIS STUDY (32 MEN; MEAN +/- SD AGE, 53.1 +/- 12.3 YEARS): YOGA THERAPY GROUP (N = 25) AND CONTROL GROUP (N = 24). IN THE YOGA GROUP, SIGNIFICANT IMPROVEMENTS WERE OBSERVED IN A TOTAL LENGTH OF TRUNK MOTION, THE ROMBERG RATIO, AND ANTEFLEXION IN STANDING AT WEEK 8 (MEAN +/- SD: 63.9 +/- 40.7-53.4 +/- 26.2 CM, 1.6 +/- 0.9-1.1 +/- 0.6, AND -8.7 +/- 9.5 TO -3.8 +/- 12.4 CM, RESPECTIVELY) WHILE THERE WERE NO SIGNIFICANT CHANGES IN THE CONTROL GROUP. HOWEVER, THOSE CLINICAL GAINS RETURNED TO THE BASELINE LEVEL AT WEEK 16. CONCLUSIONS: THE RESULTS CONFIRMED THE BENEFICIAL EFFECTS OF THE YOGA THERAPY ON POSTURAL STABILITY IN PATIENTS WITH SCHIZOPHRENIA. HOWEVER, THE THERAPEUTIC EFFECTS SEEMED TRANSIENT, WHICH WARRANTS FURTHER INVESTIGATIONS ON STRATEGIES TO SUSTAIN THE IMPROVEMENTS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
3 1373  28 IMPACT OF A YOGA INTERVENTION ON PHYSICAL ACTIVITY, SELF-EFFICACY, AND MOTIVATION IN WOMEN WITH PTSD SYMPTOMS. BACKGROUND: STUDIES USING YOGA HAVE DEMONSTRATED INITIAL EFFICACY FOR TREATING SYMPTOMS ACROSS ANXIETY DISORDERS, INCLUDING POSTTRAUMATIC STRESS DISORDER. OBJECTIVE: UNDERSTANDING HOW INTERVENTIONS INFLUENCE PARTICIPANTS' PHYSICAL ACTIVITY AND WHAT DETERMINANTS AFFECT CONTINUED PHYSICAL ACTIVITY BEHAVIOR CHANGE IS IMPORTANT BECAUSE MAINTENANCE OF THE BEHAVIOR MAY BE CRITICAL TO CONTINUED MENTAL HEALTH GAINS AND SYMPTOM REDUCTION. METHODS: THIS STUDY INVESTIGATED CHANGE IN PHYSICAL ACTIVITY AND POSSIBLE PSYCHOLOGICAL MECHANISMS OF PHYSICAL ACTIVITY BEHAVIOR CHANGE, INCLUDING SELF-EFFICACY AND REGULATORY MOTIVATION, IN A RANDOMIZED CONTROLLED TRIAL OF YOGA FOR WOMEN WITH POST-TRAUMATIC STRESS DISORDER SYMPTOMS (N=38). RESULTS: GROWTH CURVE MODELING RESULTS SHOWED NO SIGNIFICANT CHANGES IN PHYSICAL ACTIVITY OR SELF-EFFICACY FOR EITHER GROUP, WHEREAS EXTERNAL MOTIVATION DECREASED SIGNIFICANTLY IN THE YOGA GROUP BUT NOT IN THE CONTROL GROUP. CONCLUSIONS: INVESTIGATORS OF FUTURE YOGA INTERVENTIONS MAY WANT TO FOCUS ON INCREASING SELF-EFFICACY AND INTERNAL REGULATORY MOTIVATION, SO THAT PHYSICAL ACTIVITY AND RESULTANT SYMPTOM RELIEF CAN BE MAINTAINED.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
4 1942  36 SAFETY AND FEASIBILITY OF MODIFIED CHAIR-YOGA ON FUNCTIONAL OUTCOME AMONG ELDERLY AT RISK FOR FALLS. FALLS ARE AMONG THE MOST COMMON PROBLEMS AFFECTING OLDER ADULTS. AT LEAST 50% OF THOSE OVER THE AGE OF 80 FALL ANNUALLY. THE GOAL OF THIS PILOT STUDY WAS TO ASSESS THE SAFETY AND FEASIBILITY OF STRUCTURED YOGA IN AN ELDERLY POPULATION WITH FALL RISK. SENIORS AT RISK FOR FALLS WERE IDENTIFIED AND ENROLLED IN A SINGLE ARM PILOT TRIAL. A CHAIR BASED YOGA PROGRAM WAS PROVIDED TWICE A WEEK FOR 8 WEEKS. THE PROGRAM WAS DESIGNED FROM PREVIOUSLY PUBLISHED PILOT DATA. A BATTERY OF VALIDATED INSTRUMENTS WAS ADMINISTERED AT BASELINE AND WEEK EIGHT AND WAS USED TO IDENTIFY WHICH INSTRUMENTS MAY BE SENSITIVE TO CHANGE AS A RESULT OF A YOGA PROGRAM. AMONG SIXTEEN SENIORS (MEDIAN AGE OF 88) WITH A PREVIOUS HISTORY OF FALLS, 87% PROVIDED DATA FOR ASSESSMENT AT THE END OF THE INTERVENTION. TWO PATIENTS WITHDREW, ONE DUE TO A FALL OUTSIDE THE INSTITUTION AND THE OTHER DUE TO LACK OF TIME AND INTEREST. THERE WERE NO ADVERSE EVENTS DURING THE YOGA SESSIONS. PAIRED-T TESTS COMPARED PRE-POST CHANGES AND GAINS WERE NOTED IN FEAR OF FALLING (5.27 TO 2.60; P = 0.029) AND SPPB SIT TO STAND SUBSCALE (0.31 TO 1.00; P =.022). IMPROVED TRENDS WERE NOTED IN ANXIETY AND THE TIMED UP AND GO ASSESSMENTS. WE FOUND THE MODIFIED CHAIR-YOGA PROGRAM IS SAFE AND RECRUITMENT IS FEASIBLE. OUR DATA SUGGESTS THAT YOGA MAY BE BENEFICIAL IN IMPROVING MOBILITY AND REDUCING FEAR OF FALLING WHICH WARRANTS ADDITIONAL RESEARCH VIA RANDOMIZED CONTROLLED TRIAL.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
5 2372  34 WHAT HELPS OLDER PEOPLE PERSEVERE WITH YOGA CLASSES? A REALIST PROCESS EVALUATION OF A COVID-19-AFFECTED YOGA PROGRAM FOR FALL PREVENTION. BACKGROUND: FALLS AMONG OLDER PEOPLE ARE A MAJOR GLOBAL HEALTH CONCERN. THIS PROCESS EVALUATION INVESTIGATES THE EXPERIENCE OF PARTICIPANTS AGED 60+ IN A YOGA PROGRAM AIMED AT PREVENTING FALLS WHICH TRANSITIONED FROM STUDIO-BASED CLASSES TO ONLINE CLASSES IN RESPONSE TO COVID-19 RESTRICTIONS. WE SOUGHT TO UNDERSTAND HOW THE SUCCESSFUL AGEING (SAGE) YOGA PROGRAM FUNCTIONED IN BOTH SETTINGS AND AS A HYBRID PROGRAM, AND TO EXPLAIN WHY IT WORKED WELL FOR MOST PARTICIPANTS. METHODS: REALIST PROCESS EVALUATION WAS USED TO EXPLORE THE FACTORS THAT FACILITATED A SUCCESSFUL TRANSITION FOR MOST PARTICIPANTS, AND TO CONSIDER WHY IT DID NOT WORK FOR A MINORITY. THIS APPROACH DEVELOPS PROGRAM THEORIES THAT DESCRIBE WHICH MECHANISMS AN INTERVENTION IS (OR IS NOT) ACTIVATING, AND HOW THIS IS MEDIATED BY CONTEXT TO GENERATE PROCESS OUTCOMES. DATA INCLUDED INTERVIEWS WITH PARTICIPANTS (N = 21) AND YOGA INSTRUCTORS (N = 3), SELF-REPORT FEEDBACK FORMS (N = 46), OBSERVATION OF CLASSES AND ROUTINE PROCESS MEASURES. RESULTS: FACTORS THAT FACILITATED A SUCCESSFUL TRANSITION FOR MOST PARTICIPANTS INCLUDED THE QUALITY OF YOGA INSTRUCTION, THE PROGRAM FORMAT AND INHERENT CHARACTERISTICS OF YOGA. GAINS IN TRANSITIONING ONLINE INCLUDED CONTINUITY AND GREATER CONVENIENCE. LOSSES INCLUDED PERCEIVED REDUCTION IN THE EFFECTIVENESS OF YOGA INSTRUCTION. THERE WERE GREATER CHALLENGES FOR PEOPLE STRUGGLING WITH PAIN AND IN DISADVANTAGEOUS HOME ENVIRONMENTS. WE IDENTIFIED SIX PROGRAM THEORIES CONFIGURED AROUND 16 MECHANISMS: 1. IT'S WORTH THE EFFORT AND 2. IN EXPERT HANDS (THESE HAD THE SAME MECHANISMS: VALUE EXPECTANCY, THERAPEUTIC ALLIANCE AND ACHIEVEMENT/MASTERY), 3. A COMMUNAL EXPERIENCE (THESE MECHANISMS WERE SHARED EXPERIENCE, SOCIAL CONNECTION, SOCIAL COMPARISON AND PEER CHECKING), 4. PUTTING YOGA WITHIN REACH (ACCESSIBILITY, CONVENIENCE, GRATITUDE), 5. BUILDING YOGA HABITS (PURPOSEFUL STRUCTURE, MOMENTUM, ACCOUNTABILITY AND CONTINUITY), AND 6. YOGA'S SPECIAL PROPERTIES (EMBODIMENT AND MINDFULNESS). CONCLUSIONS: THIS STUDY SHOWED THAT ONLINE DELIVERY OF A YOGA PROGRAM FOR PEOPLE AGED 60+ RETAINED MUCH OF THE VALUE OF A FACE-TO-FACE PROGRAM FOR THE MAJORITY OF PARTICIPANTS, AND INCREASED THE VALUE FOR SOME. THE STRUCTURED, COMMUNAL NATURE OF AN ORGANISED GROUP PROGRAM DELIVERED BY A SKILLED INSTRUCTOR, TOGETHER WITH YOGA'S INTRINSIC FOCUS ON MINDFULNESS, FACILITATED CONTINUED ENGAGEMENT AND PERCEIVED HEALTH BENEFITS, DESPITE THE CHANGE IN DELIVERY MODE.	2022	

6 1291  27 GROUP ACUPUNCTURE THERAPY WITH YOGA THERAPY FOR CHRONIC NECK, LOW BACK, AND OSTEOARTHRITIS PAIN IN SAFETY NET SETTING FOR AN UNDERSERVED POPULATION: DESIGN AND RATIONALE FOR A FEASIBILITY PILOT. CHRONIC PAIN IS PREVALENT IN THE UNITED STATES, WITH IMPACT ON PHYSICAL AND PSYCHOLOGICAL FUNCTIONING AS WELL AS LOST WORK PRODUCTIVITY. MINORITY AND LOWER SOCIOECONOMIC POPULATIONS HAVE INCREASED PREVALENCE OF CHRONIC PAIN WITH LESS ACCESS TO PAIN CARE, POORER OUTCOMES, AND HIGHER RISK OF FATAL OPIOID OVERDOSE. ACUPUNCTURE THERAPY IS EFFECTIVE IN TREATING CHRONIC PAIN CONDITIONS INCLUDING CHRONIC LOW BACK PAIN, NECK PAIN, SHOULDER PAIN, AND KNEE PAIN FROM OSTEOARTHRITIS. ACUPUNCTURE THERAPY, INCLUDING GROUP ACUPUNCTURE, IS FEASIBLE AND EFFECTIVE, AND SPECIFICALLY SO FOR UNDERSERVED AND DIVERSE POPULATIONS AT RISK FOR HEALTH OUTCOME DISPARITIES. ACUPUNCTURE THERAPY ALSO ENCOURAGES PATIENT ENGAGEMENT AND ACTIVATION. AS CHRONIC PAIN IMPROVES, THERE IS A NATURAL PROGRESSION TO WANT AND NEED TO INCREASE ACTIVITY AND MOVEMENT RECOVERY. DIVERSE MOVEMENT APPROACHES ARE IMPORTANT FOR IMPROVING RANGE OF MOTION, MAINTAINING GAINS, STRENGTHENING, AND PROMOTING PATIENT ENGAGEMENT AND ACTIVATION. YOGA THERAPY IS AN ACTIVE THERAPY WITH PROVEN BENEFIT IN MUSCULOSKELETAL PAIN DISORDERS AND PAIN ASSOCIATED DISABILITY. THE AIM OF THIS QUASI-EXPERIMENTAL PILOT FEASIBILITY TRIAL IS TO TEST THE BUNDLING OF THESE 2 EFFECTIVE CARE OPTIONS FOR CHRONIC PAIN, TO INFORM BOTH THE DESIGN FOR A LARGER RANDOMIZED PRAGMATIC EFFECTIVENESS TRIAL AS WELL AS IMPLEMENTATION STRATEGIES ACROSS UNDERSERVED SETTINGS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
7  199  33 A RESEARCH PROTOCOL FOR A PILOT, RANDOMIZED CONTROLLED TRIAL DESIGNED TO EXAMINE THE FEASIBILITY OF A DYADIC VERSUS INDIVIDUAL YOGA PROGRAM FOR FAMILY CAREGIVERS OF GLIOMA PATIENTS UNDERGOING RADIOTHERAPY. BACKGROUND: ALTHOUGH THE DIAGNOSIS AND TREATMENT OF A PRIMARY BRAIN TUMOR PRESENT UNIQUE CHALLENGES TO PATIENTS AND THEIR FAMILY CAREGIVERS, EVIDENCE-BASED SUPPORTIVE CARE INTERVENTIONS ARE GENERALLY LACKING. THE PRIMARY AIM OF THIS RESEARCH PROTOCOL IS TO DETERMINE THE FEASIBILITY OF IMPLEMENTING A DYADIC YOGA (DY) VERSUS A CAREGIVER YOGA (CY) INTERVENTION OR A WAIT-LIST CONTROL (WLC) GROUP USING A RANDOMIZED CONTROLLED TRIAL DESIGN. METHODS: SEVENTY-FIVE GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR FAMILY CAREGIVERS ARE RANDOMIZED TO THE DY, CY, OR A WLC GROUP. PATIENT-CAREGIVER DYADS IN THE DY GROUP AND CAREGIVERS IN THE CY GROUP RECEIVE 15 SESSIONS (45 MIN EACH) OVER THE COURSE OF PATIENTS' STANDARD RADIOTHERAPY (6 WEEKS). PATIENTS AND CAREGIVERS IN ALL GROUPS COMPLETE BASELINE ASSESSMENTS OF SYMPTOMS, QUALITY OF LIFE (QOL), AND HEALTH UTILIZATION OUTCOMES PRIOR TO RANDOMIZATION. FOLLOW-UP ASSESSMENTS ARE PERFORMED 6 WEEKS AND THEN AGAIN 3 MONTHS LATER. THE PRIMARY OUTCOME IS FEASIBILITY (I.E., >/= 50% OF ELIGIBLE DYADS CONSENT, >/= 70% OF ENROLLED DYADS COMPLETE ALL ASSESSMENTS, AND >/= 50% OF ALL PRACTICE SESSIONS ARE ATTENDED). WE WILL ALSO PERFORM PRIMARILY DESCRIPTIVE ANALYSES OF THE SELF-REPORTED OUTCOMES (E.G., FATIGUE, OVERALL QOL) AND EXPLORE POTENTIAL INTERVENTION MODERATORS (E.G., PERFORMANCE STATUS) TO INFORM A LARGER FUTURE TRIAL. CONCLUSION: THIS TRIAL WILL PROVIDE IMPORTANT INFORMATION REGARDING THE FEASIBILITY OF A DYADIC VERSUS A CAREGIVER YOGA INTERVENTION REGARDING SYMPTOM, QOL, AND HEALTH UTILIZATION OUTCOMES IN GLIOMA PATIENTS AND THEIR CAREGIVERS. TRIAL REGISTRATION: CLINICALTRIALS.GOV NCT02481349.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
8  345  30 ASSESSING FEASIBILITY AND ACCEPTABILITY OF YOGA AND GROUP CBT FOR ADOLESCENTS WITH DEPRESSION: A PILOT RANDOMIZED CLINICAL TRIAL. PURPOSE: GIVEN INCREASING RATES OF DEPRESSION IN ADOLESCENTS, THERE IS A CLEAR NEED FOR INNOVATIVE TREATMENTS. IN THIS PILOT RANDOMIZED CLINICAL TRIAL, WE ASSESSED ACCEPTABILITY AND FEASIBILITY OF TWO GROUP-BASED INTERVENTIONS: YOGA AND COGNITIVE-BEHAVIORAL THERAPY (CBT). THE GOAL OF THIS WORK IS TO PREPARE FOR A FUTURE FULLY POWERED RANDOMIZED TRIAL TO TEST THE HYPOTHESIS THAT YOGA IS NOT INFERIOR TO AN ESTABLISHED ADOLESCENT DEPRESSION TREATMENT, NAMELY, GROUP CBT. METHODS: WE ENROLLED 42 ADOLESCENTS WITH ELEVATED DEPRESSION SYMPTOMS. PARTICIPANTS WERE RANDOMLY ASSIGNED TO A 12-WEEK GROUP-BASED INTERVENTION, YOGA OR CBT. WE HAD A PRIORI FEASIBILITY AND ACCEPTABILITY TARGETS, INCLUDING FOR RECRUITMENT RATE, RETENTION RATE, EXPECTANCY, CREDIBILITY, PROGRAM SATISFACTION, CLASS ATTENDANCE, ENGAGEMENT IN HOME PRACTICE, AND INSTRUCTOR/LEADER MANUAL ADHERENCE. WE ASSESSED ADVERSE EVENTS, AND WITHIN-SUBJECT CHANGES IN OUTCOMES (DEPRESSION, ANXIETY, IMPAIRMENT, SLEEP DISTURBANCE) AND POSSIBLE MEDIATORS (MINDFULNESS, SELF-COMPASSION). RESULTS: BOTH INTERVENTIONS MET MOST ACCEPTABILITY AND FEASIBILITY TARGETS. THE ONLY TARGET NOT MET RELATED TO LOW ENGAGEMENT IN HOME PRACTICE. PARTICIPANTS WITHIN EACH STUDY ARM SHOWED DECREASED DEPRESSION SYMPTOMS OVER TIME AND INCREASED SELF-COMPASSION. CONCLUSIONS: A YOGA INTERVENTION APPEARS TO BE ACCEPTABLE AND FEASIBLE TO ADOLESCENTS WITH DEPRESSION. HOWEVER, IT MAY BE CHALLENGING FOR THIS GROUP TO ENGAGE IN UNSTRUCTURED HOME PRACTICE.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
9 2762  40 YOGA PROGRAM FOR HIGH-GRADE GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR FAMILY CAREGIVERS. BACKGROUND: DESPITE THEIR HIGH SYMPTOM BURDEN AND POOR PROGNOSIS, EVIDENCE-BASED SUPPORTIVE CARE INTERVENTIONS FOR ADULTS WITH HIGH-GRADE GLIOMA (HGG) AND THEIR CAREGIVERS ARE LACKING. THUS, WE AIMED TO ESTABLISH FEASIBILITY OF A PATIENT-CAREGIVER DYADIC YOGA PROGRAM (DYP) FOR NEWLY DIAGNOSED HGG PATIENTS AND THEIR FAMILY CAREGIVERS TARGETING QUALITY-OF-LIFE (QOL) OUTCOMES. METHOD: IN THIS SINGLE-ARM PILOT TRIAL, DYADS PARTICIPATED IN A 12-SESSION DYP PROGRAM ACROSS THE COURSE OF PATIENTS' RADIOTHERAPY. THE INTERVENTION FOCUSED ON BREATHING EXERCISES, GENTLE MOVEMENTS, AND GUIDED MEDITATIONS. WE TRACKED FEASIBILITY DATA AND ASSESSED LEVELS OF CANCER-RELATED SYMPTOMS (MD ANDERSON SYMPTOM INVENTORY [MDASI]), DEPRESSIVE SYMPTOMS (CENTERS FOR EPIDEMIOLOGICAL STUDIES-DEPRESSION SCALE), FATIGUE (BRIEF FATIGUE INVENTORY), SLEEP DISTURBANCES (PITTSBURGH SLEEP QUALITY INDEX [PSQI]), AND OVERALL MENTAL AND PHYSICAL QOL (36-ITEM SHORT-FORM SURVEY [SF-36]) AT BASELINE AND POST-DYP, WHICH WAS AT THE END OF RADIOTHERAPY. RESULTS: WE APPROACHED 6 DYADS OF WHICH 5 DYADS (86%) CONSENTED AND COMPLETED ALL 12 SESSIONS AND PRE/POST ASSESSMENTS. ALL PATIENTS (MEAN AGE: 52 YEARS, 80% FEMALE, 80% GRADE IV) AND CAREGIVERS (MEAN AGE: 58 YEARS, 80% FEMALE, 60% SPOUSES) PERCEIVED BENEFIT FROM THE PROGRAM. PAIRED T TESTS REVEALED A MARGINALLY SIGNIFICANT, YET CLINICALLY MEANINGFUL, DECREASE IN PATIENT'S CANCER SYMPTOMS ( T = 2.32, P = .08; MDASI MEAN; PRE = 1.75, POST = 1.04). THERE WERE CLINICALLY SIGNIFICANT REDUCTIONS IN PATIENT SLEEP DISTURBANCES (PSQI MEAN: PRE = 10.75, POST = 8.00) AND IMPROVEMENTS IN PATIENT AND CAREGIVER MENTAL QOL (MCS OF SF-36 MEAN: PRE = 42.35, POST = 52.34, AND PRE = 45.14, POST = 51.43, RESPECTIVELY). CONCLUSIONS: THIS NOVEL SUPPORTIVE CARE PROGRAM APPEARS TO BE SAFE, FEASIBLE, ACCEPTABLE, AND SUBJECTIVELY USEFUL FOR HGG PATIENTS AND THEIR CAREGIVERS. THERE WAS ALSO PRELIMINARY EVIDENCE REGARDING QOL TREATMENT GAINS FOR BOTH PATIENTS AND CAREGIVERS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
10 1194  35 EXAMINING MEDIATORS AND MODERATORS OF YOGA FOR WOMEN WITH BREAST CANCER UNDERGOING RADIOTHERAPY. HYPOTHESIS THIS STUDY EXAMINES MODERATORS AND MEDIATORS OF A YOGA INTERVENTION TARGETING QUALITY-OF-LIFE (QOL) OUTCOMES IN WOMEN WITH BREAST CANCER RECEIVING RADIOTHERAPY.METHODS WOMEN UNDERGOING 6 WEEKS OF RADIOTHERAPY WERE RANDOMIZED TO A YOGA (YG; N = 53) OR STRETCHING (ST; N = 56) INTERVENTION OR A WAITLIST CONTROL GROUP (WL; N = 54). DEPRESSIVE SYMPTOMS AND SLEEP DISTURBANCES WERE MEASURED AT BASELINE. MEDIATOR (POSTTRAUMATIC STRESS SYMPTOMS, BENEFIT FINDING, AND CORTISOL SLOPE) AND OUTCOME (36-ITEM SHORT FORM [SF]-36 MENTAL AND PHYSICAL COMPONENT SCALES [MCS AND PCS]) VARIABLES WERE ASSESSED AT BASELINE, END-OF-TREATMENT, AND 1-, 3-, AND 6-MONTHS POSTTREATMENT. RESULTS BASELINE DEPRESSIVE SYMPTOMS (P = .03) AND SLEEP DISTURBANCES (P < .01) MODERATED THE GROUP X TIME EFFECT ON MCS, BUT NOT PCS. WOMEN WITH HIGH BASELINE DEPRESSIVE SYMPTOMS IN YG REPORTED MARGINALLY HIGHER 3-MONTH MCS THAN THEIR COUNTERPARTS IN WL (P = .11). WOMEN WITH HIGH BASELINE SLEEP DISTURBANCES IN YG REPORTED HIGHER 3-MONTHS MCS THAN THEIR COUNTERPARTS IN WL (P < .01) AND HIGHER 6-MONTH MCS THAN THEIR COUNTERPARTS IN ST (P = .01). YG LED TO GREATER BENEFIT FINDING THAN ST AND WL ACROSS THE FOLLOW-UP (P = .01). THREE-MONTH BENEFIT FINDING PARTIALLY MEDIATED THE EFFECT OF YG ON 6-MONTH PCS. POSTTRAUMATIC STRESS SYMPTOMS AND CORTISOL SLOPE DID NOT MEDIATE TREATMENT EFFECT ON QOL. CONCLUSION YOGA MAY PROVIDE THE GREATEST MENTAL-HEALTH-RELATED QOL BENEFITS FOR THOSE EXPERIENCING PRE-RADIOTHERAPY SLEEP DISTURBANCE AND DEPRESSIVE SYMPTOMS. YOGA MAY IMPROVE PHYSICAL-HEALTH-RELATED QOL BY INCREASING ABILITY TO FIND BENEFIT IN THE CANCER EXPERIENCE.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
11  252  29 A YOGA PROGRAM FOR THE SYMPTOMS OF POST-TRAUMATIC STRESS DISORDER IN VETERANS. THE PURPOSE OF THIS PILOT STUDY WAS TO EVALUATE THE FEASIBILITY AND EFFECTIVENESS OF A YOGA PROGRAM AS AN ADJUNCTIVE THERAPY FOR IMPROVING POST-TRAUMATIC STRESS DISORDER (PTSD) SYMPTOMS IN VETERANS WITH MILITARY-RELATED PTSD. VETERANS (N = 12) PARTICIPATED IN A 6 WEEK YOGA INTERVENTION HELD TWICE A WEEK. THERE WAS SIGNIFICANT IMPROVEMENT IN PTSD HYPERAROUSAL SYMPTOMS AND OVERALL SLEEP QUALITY AS WELL AS DAYTIME DYSFUNCTION RELATED TO SLEEP. THERE WERE NO SIGNIFICANT IMPROVEMENTS IN THE TOTAL PTSD, ANGER, OR QUALITY OF LIFE OUTCOME SCORES. THESE RESULTS SUGGEST THAT THIS YOGA PROGRAM MAY BE AN EFFECTIVE ADJUNCTIVE THERAPY FOR IMPROVING HYPERAROUSAL SYMPTOMS OF PTSD INCLUDING SLEEP QUALITY. THIS STUDY DEMONSTRATES THAT THE YOGA PROGRAM IS ACCEPTABLE, FEASIBLE, AND THAT THERE IS GOOD ADHERENCE IN A VETERAN POPULATION.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
12 1748  36 PILOT RANDOMIZED, CONTROLLED TRIAL OF A DYADIC YOGA PROGRAM FOR GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR FAMILY CAREGIVERS. BACKGROUND: WHILE THE USE OF BEHAVIORAL MEDICINE IN MANAGING GLIOMA PATIENTS' SYMPTOMS IS NOT WELL STUDIED, THE HIGH SYMPTOM BURDEN IN PATIENTS AND THEIR FAMILY CAREGIVERS IS WELL ESTABLISHED. WE CONDUCTED A PILOT RANDOMIZED, CONTROLLED TRIAL TO EXAMINE THE FEASIBILITY AND PRELIMINARY EFFICACY OF A DYADIC YOGA (DY) INTERVENTION AS A SUPPORTIVE CARE STRATEGY. METHODS: GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR CAREGIVERS WERE RANDOMIZED TO A 12-SESSION DY OR WAITLIST CONTROL (WLC) GROUP. PRIOR TO RADIOTHERAPY AND RANDOMIZATION, BOTH GROUPS COMPLETED MEASURES OF CANCER-RELATED SYMPTOMS (MD ANDERSON SYMPTOM INVENTORY-BRAIN TUMOR MODULE), DEPRESSIVE SYMPTOMS (CENTER FOR EPIDEMIOLOGICAL STUDIES-DEPRESSION MEASURE), FATIGUE (BRIEF FATIGUE INVENTORY), AND OVERALL QUALITY OF LIFE (QOL; MEDICAL OUTCOMES STUDY 36-ITEM SHORT-FORM SURVEY). DYADS WERE REASSESSED AT THE LAST DAY OF RADIOTHERAPY. RESULTS: TWENTY PATIENTS (MEAN AGE: 46 YEARS, 50% FEMALE, 80% WHO GRADE IV AND CAREGIVERS (MEAN AGE: 50 YEARS, 70% FEMALE, 50% SPOUSES) PARTICIPATED IN THE TRIAL. A PRIORI FEASIBILITY CRITERIA WERE MET REGARDING CONSENT (70%), ADHERENCE (88%), AND RETENTION (95%) RATES. CONTROLLING FOR RELEVANT COVARIATES, CHANGE SCORE ANALYSES REVEALED CLINICALLY SIGNIFICANT IMPROVEMENTS FOR PATIENTS IN THE DY COMPARED WITH THE WLC GROUP FOR OVERALL CANCER SYMPTOM SEVERITY (D = 0.96) AND SYMPTOM INTERFERENCE (D = 0.74), DEPRESSIVE SYMPTOMS (D = 0.71), AND MENTAL QOL (D = 0.69). CAREGIVERS IN THE DY GROUP REPORTED CLINICALLY SIGNIFICANT IMPROVEMENTS IN DEPRESSIVE SYMPTOMS (D = 1.12), FATIGUE (D = 0.89), AND MENTAL QOL (D = 0.49) RELATIVE TO THOSE IN THE WLC GROUP. CONCLUSION: A DY INTERVENTION APPEARS TO BE A FEASIBLE AND BENEFICIAL SYMPTOM AND QOL MANAGEMENT STRATEGY FOR GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR CAREGIVERS. AN EFFICACY TRIAL WITH A MORE STRINGENT CONTROL GROUP IS WARRANTED. CLINICAL TRIAL NUMBER: NCT02481349.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
13 1375  40 IMPACT OF DAILY YOGA-BASED EXERCISE ON PAIN, CATASTROPHIZING, AND SLEEP AMONGST INDIVIDUALS WITH FIBROMYALGIA. BACKGROUND: FIBROMYALGIA (FM) IS A CHRONIC WIDESPREAD PAIN DISORDER CHARACTERIZED BY NEGATIVE AFFECT, SLEEP DISTURBANCE, AND FATIGUE. THIS UNCONTROLLED PILOT STUDY INVESTIGATED THE EFFICACY OF DAILY YOGA-BASED EXERCISE TO IMPROVE FM SYMPTOMS AND EXPLORED BASELINE PHENOTYPIC CHARACTERISTICS ASSOCIATED WITH THE GREATEST BENEFIT. METHODS: FM PATIENTS (N=46, WITH 36 COMPLETERS) REPORTED PSYCHOSOCIAL FUNCTIONING AND A RANGE OF FM SYMPTOMS USING VALIDATED INSTRUMENTS BEFORE AND AFTER PARTICIPATION IN SATYANANDA YOGA, WHICH INCLUDED WEEKLY IN-PERSON PAIN-TAILORED GROUP CLASSES FOR 6 WEEKS AND DAILY HOME YOGA VIDEO PRACTICE. RESULTS: CHANGES IN FM SYMPTOMS FROM PRE- TO POST-YOGA WERE VARIABLE AMONGST PARTICIPANTS. GROUP MEANS FOR PAIN DECREASED, AS REPORTED BY AVERAGE DAILY DIARY AND BRIEF PAIN INVENTORY, WITH GREATER HOME PRACTICE MINUTES ASSOCIATED WITH A GREATER DECREASE IN PAIN. AVERAGE DAILY RATINGS OF SLEEP AND FATIGUE IMPROVED. PAIN CATASTROPHIZING WAS DECREASED OVERALL, WITH GREATER CHANGE CORRELATED TO A DECREASE IN FM SYMPTOMS. WE DID NOT OBSERVE ANY GROUP MEAN CHANGES IN ACTIGRAPHY SLEEP EFFICIENCY, PATIENT-REPORTED OUTCOMES MEASUREMENT INFORMATION SYSTEM-ANXIETY AND THE REVISED FIBROMYALGIA IMPACT QUESTIONNAIRE. MULTILEVEL MODELING ANALYSIS REVEALED A SIGNIFICANT INTERACTION BETWEEN ANXIETY AND CATASTROPHIZING FOR END-STUDY SLEEP EFFICIENCY, FATIGUE, AND PAIN, SUCH THAT PATIENTS WITH HIGHER BASELINE CATASTROPHIZING AND LOWER BASELINE ANXIETY REPORTED LESS PAIN AND FATIGUE, AND HIGHER SLEEP EFFICIENCY AFTER THE SIXTH WEEK OF YOGA PRACTICE. CONCLUSION: THIS PILOT STUDY SUGGESTS THAT YOGA MAY REDUCE PAIN AND CATASTROPHIZING, AS WELL AS IMPROVE SLEEP, BUT THESE CHANGES WERE MODEST ACROSS STUDY PARTICIPANTS. GREATER UPTAKE OF HOME YOGA PRACTICE AS WELL AS A PHENOTYPE OF HIGHER BASELINE CATASTROPHIZING COMBINED WITH LOWER BASELINE ANXIETY WERE ASSOCIATED WITH GREATER IMPACT. FUTURE RANDOMIZED, CONTROLLED TRIALS COMPARING DIFFERENT TYPES OF YOGA OR EXERCISE WILL ALLOW DETERMINATION OF THE MOST EFFECTIVE TREATMENTS FOR FM AND ALLOW CLOSER TARGETING TO THE PATIENTS WHO WILL BENEFIT MOST FROM THEM.	2019	
                                                                                                                                                                                                                                                                                                                                                                            
14 1164  42 EVALUATING THE EFFECTS OF A YOGA-BASED PROGRAM INTEGRATED WITH THIRD-WAVE COGNITIVE BEHAVIORAL THERAPY COMPONENTS ON SELF-REGULATION IN CHILDREN ON THE AUTISM SPECTRUM: A PILOT RANDOMIZED CONTROLLED TRIAL. LAY ABSTRACT: CHILDREN ON THE AUTISM SPECTRUM MAY EXPERIENCE DIFFICULTIES WITH THE REGULATION OF ATTENTION, THOUGHTS, EMOTIONS, AND BEHAVIOR, UNDERSTANDING, AND EXPRESSING THEIR EMOTIONS APPROPRIATELY, AS WELL AS ANXIETY, AND SLEEP. IN AUTISM RESEARCH, CONTEMPLATIVE PRACTICES THAT WORK THROUGH BOTH BODY AND MIND HAVE SHOWN TENTATIVELY PROMISING RESULTS. HOWEVER, THERE ARE LIMITED STUDIES ON THIS TOPIC, AND THE USE OF YOGA TO FACILITATE EXECUTIVE CONTROL HAS NOT BEEN RESEARCHED YET. THE INCREDIBLE EXPLORERS (6-WEEK PROGRAM), A YOGA-INFORMED INTERVENTION PROGRAM FOR CHILDREN (8-12 YEARS), WAS DEVELOPED TO UNDERSTAND WHETHER, FOR CHILDREN ON THE AUTISM SPECTRUM, THE TRAINING COULD IMPROVE THE ABILITY TO SELF-REGULATE, REDUCE ANXIETY AND SLEEP PROBLEMS, AND INCREASE AWARENESS OF EMOTIONS. IN OUR SAMPLE, 61 CHILDREN WITH ONE OF THEIR PARENTS COMPLETED THE PROGRAM. HALF OF THE GROUP RECEIVED THE INTERVENTION, AND THE OTHER HALF HAD TO WAIT UNTIL THE YOGA GROUP COMPLETED THEIR TRIAL. THE PARTICIPANTS WERE ASKED TO GIVE THEIR FEEDBACK IMMEDIATELY AFTER PROGRAM COMPLETION AND AT 6-WEEK FOLLOW-UP. COMPARED TO THE GROUP THAT WAS WAITING TO RECEIVE THE INTERVENTION, PARENTS IN THE YOGA GROUP REPORTED SIGNIFICANT GAINS FOR THEIR CHILDREN IN REGULATING THEIR OVERALL EXECUTIVE CONTROL IMMEDIATELY AFTER THE SESSION AND AGAIN AT FOLLOW-UP. THE PARENTS REPORTED A REDUCTION IN SOME OF THE SLEEP PROBLEMS POST-TREATMENT. CHILDREN INDICATED AN IMPROVED ABILITY TO COMMUNICATE THEIR FEELINGS AND WILLINGNESS TO ANALYZE THEIR EMOTIONS POST-INTERVENTION. HOWEVER, THE STUDY HAD SEVERAL SHORTCOMINGS AND GIVEN THAT THIS WAS THE FIRST TRIAL OF THE PROGRAM, THE RESULTS NEED TO BE INTERPRETED WITH CAUTION. FURTHER RESEARCH IS RECOMMENDED.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
15 1267  47 FOLLOW-UP OF YOGA OF AWARENESS FOR FIBROMYALGIA: RESULTS AT 3 MONTHS AND REPLICATION IN THE WAIT-LIST GROUP. OBJECTIVES: PUBLISHED PRELIMINARY FINDINGS FROM A RANDOMIZED-CONTROLLED TRIAL SUGGEST THAT AN 8-WEEK YOGA OF AWARENESS INTERVENTION MAY BE EFFECTIVE FOR IMPROVING SYMPTOMS, FUNCTIONAL DEFICITS, AND COPING ABILITIES IN FIBROMYALGIA. THE PRIMARY AIMS OF THIS STUDY WERE TO EVALUATE THE SAME INTERVENTION'S POSTTREATMENT EFFECTS IN A WAIT-LIST GROUP AND TO TEST THE INTERVENTION'S EFFECTS AT 3-MONTH FOLLOW-UP IN THE IMMEDIATE TREATMENT GROUP. METHODS: UNPAIRED T TESTS WERE USED TO COMPARE DATA FROM A PER PROTOCOL SAMPLE OF 21 WOMEN IN THE IMMEDIATE TREATMENT GROUP WHO HAD COMPLETED TREATMENT AND 18 WOMEN IN THE WAIT-LIST GROUP WHO HAD COMPLETED TREATMENT. WITHIN-GROUP PAIRED T TESTS WERE PERFORMED TO COMPARE POSTTREATMENT DATA WITH 3-MONTH FOLLOW-UP DATA IN THE IMMEDIATE TREATMENT GROUP. THE PRIMARY OUTCOME MEASURE WAS THE FIBROMYALGIA IMPACT QUESTIONNAIRE REVISED (FIQR). MULTILEVEL RANDOM-EFFECTS MODELS WERE ALSO USED TO EXAMINE ASSOCIATIONS BETWEEN YOGA PRACTICE RATES AND OUTCOMES. RESULTS: POSTTREATMENT RESULTS IN THE WAIT-LIST GROUP LARGELY MIRRORED RESULTS SEEN AT POSTTREATMENT IN THE IMMEDIATE TREATMENT GROUP, WITH THE FIQR TOTAL SCORE IMPROVING BY 31.9% ACROSS THE 2 GROUPS. FOLLOW-UP RESULTS SHOWED THAT PATIENTS SUSTAINED MOST OF THEIR POSTTREATMENT GAINS, WITH THE FIQR TOTAL SCORE REMAINING 21.9% IMPROVED AT 3 MONTHS. YOGA PRACTICE RATES WERE GOOD, AND MORE PRACTICE WAS ASSOCIATED WITH MORE BENEFIT FOR A VARIETY OF OUTCOMES. DISCUSSION: THESE FINDINGS INDICATE THAT THE BENEFITS OF YOGA OF AWARENESS IN FIBROMYALGIA ARE REPLICABLE AND CAN BE MAINTAINED.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
16  249  31 A YOGA INTERVENTION FOR YOUNG CHILDREN: SELF-REGULATION AND EMOTION REGULATION. YOGA-BASED INTERVENTIONS HAVE BEEN IMPLEMENTED IN SCHOOLS AND DEMONSTRATED PROMISING RESULTS ON STUDENTS' SELF-REGULATION OUTCOMES. NEVERTHELESS, THERE IS LIMITED LITERATURE ON THE EFFECTS THAT YOGA MAY HAVE FOR CHILDREN IN THE EARLY PRIMARY GRADES, DESPITE THE EVIDENCE DEMONSTRATING THAT THIS IS AN OPPORTUNE PERIOD IN DEVELOPMENT FOR EARLY SELF-REGULATION. FEW STUDIES HAVE FOCUSED ON YOUNG CHILDREN LIVING IN THE CONTEXT OF ECONOMIC DIFFICULTY, WHICH CAN HINDER CHILDREN'S DEVELOPMENT OF SELF-REGULATORY SKILLS AND EDUCATIONAL TRAJECTORIES. THE EFFECTS OF AN EIGHT-WEEK YOGA INTERVENTION ON ECONOMICALLY DISADVANTAGED PRE-KINDERGARTEN AND KINDERGARTEN CHILDREN'S SELF-REGULATION AND EMOTION REGULATION WERE EXAMINED VIA A PAIRED WITHIN-SUBJECTS COMPARISON STUDY. NINE CLASSROOMS WERE ASSIGNED TO THE YOGA INTERVENTION (TREATMENT FIRST, TXFIRST; N = 90) OR A WAIT-LIST CONTROL GROUP (TREATMENT SECOND, TXSECOND; N = 64). ALL CHILDREN WERE ASSESSED AT PRE-INTERVENTION (TIME 1), POST-INTERVENTION ASSESSMENT FOR TXFIRST (TIME 2), AND POST-INTERVENTION ASSESSMENT FOR TXSECOND (TIME 3). CHILDREN DEMONSTRATED SIGNIFICANT PREDICTED GAINS ON A BEHAVIORAL TASK OF SELF-REGULATION AND DECLINES IN TEACHER-RATED SUBMISSIVE VENTING AND TOTAL BEHAVIOR PROBLEMS. IMPLICATIONS FOR FUTURE RESEARCH ARE DISCUSSED, WITH A FOCUS ON INCLUDING FOLLOW-UP ASSESSMENTS AND MULTIPLE DIMENSIONS OF FIDELITY OF IMPLEMENTATION.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
17 2604  49 YOGA FOR PERSISTENT FATIGUE IN BREAST CANCER SURVIVORS: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: CANCER-RELATED FATIGUE AFFLICTS UP TO 33% OF BREAST CANCER SURVIVORS, YET THERE ARE NO EMPIRICALLY VALIDATED TREATMENTS FOR THIS SYMPTOM. METHODS: THE AUTHORS CONDUCTED A 2-GROUP RANDOMIZED CONTROLLED TRIAL TO DETERMINE THE FEASIBILITY AND EFFICACY OF AN IYENGAR YOGA INTERVENTION FOR BREAST CANCER SURVIVORS WITH PERSISTENT POST-TREATMENT FATIGUE. PARTICIPANTS WERE BREAST CANCER SURVIVORS WHO HAD COMPLETED CANCER TREATMENTS (OTHER THAN ENDOCRINE THERAPY) AT LEAST 6 MONTHS BEFORE ENROLLMENT, REPORTED SIGNIFICANT CANCER-RELATED FATIGUE, AND HAD NO OTHER MEDICAL CONDITIONS THAT WOULD ACCOUNT FOR FATIGUE SYMPTOMS OR INTERFERE WITH YOGA PRACTICE. BLOCK RANDOMIZATION WAS USED TO ASSIGN PARTICIPANTS TO A 12-WEEK, IYENGAR-BASED YOGA INTERVENTION OR TO 12 WEEKS OF HEALTH EDUCATION (CONTROL). THE PRIMARY OUTCOME WAS CHANGE IN FATIGUE MEASURED AT BASELINE, IMMEDIATELY POST-TREATMENT, AND 3 MONTHS AFTER TREATMENT COMPLETION. ADDITIONAL OUTCOMES INCLUDED CHANGES IN VIGOR, DEPRESSIVE SYMPTOMS, SLEEP, PERCEIVED STRESS, AND PHYSICAL PERFORMANCE. INTENT-TO-TREAT ANALYSES WERE CONDUCTED WITH ALL RANDOMIZED PARTICIPANTS USING LINEAR MIXED MODELS. RESULTS: THIRTY-ONE WOMEN WERE RANDOMLY ASSIGNED TO YOGA (N = 16) OR HEALTH EDUCATION (N = 15). FATIGUE SEVERITY DECLINED SIGNIFICANTLY FROM BASELINE TO POST-TREATMENT AND OVER A 3-MONTH FOLLOW-UP IN THE YOGA GROUP RELATIVE TO CONTROLS (P = .032). IN ADDITION, THE YOGA GROUP HAD SIGNIFICANT INCREASES IN VIGOR RELATIVE TO CONTROLS (P = .011). BOTH GROUPS HAD POSITIVE CHANGES IN DEPRESSIVE SYMPTOMS AND PERCEIVED STRESS (P < .05). NO SIGNIFICANT CHANGES IN SLEEP OR PHYSICAL PERFORMANCE WERE OBSERVED. CONCLUSIONS: A TARGETED YOGA INTERVENTION LED TO SIGNIFICANT IMPROVEMENTS IN FATIGUE AND VIGOR AMONG BREAST CANCER SURVIVORS WITH PERSISTENT FATIGUE SYMPTOMS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
18   19  31 "WE REALLY NEED THIS": TRAUMA-INFORMED YOGA FOR VETERAN WOMEN WITH A HISTORY OF MILITARY SEXUAL TRAUMA. OBJECTIVES: UP TO 70% OF WOMEN SERVICE MEMBERS IN THE UNITED STATES REPORT MILITARY SEXUAL TRAUMA (MST); MANY DEVELOP POST-TRAUMATIC STRESS DISORDER (PTSD) AND CO-OCCURRING DISORDERS. TRAUMA-INFORMED YOGA (TIY) IS SUGGESTED TO IMPROVE PSYCHIATRIC SYMPTOMS AND SHOWN FEASIBLE AND ACCEPTABLE IN EMERGING RESEARCH, YET NO WORK HAS EVALUATED TIY IN MST SURVIVORS. THE CURRENT QUALITY IMPROVEMENT PROJECT AIMED TO EXAMINE TIY'S FEASIBILITY, ACCEPTABILITY, AND PERCEIVED EFFECTS IN THE CONTEXT OF MST. DESIGN: COLLECTIVE CASE SERIES (N = 7). SETTING: NEW ENGLAND VET CENTER. INTERVENTIONS: EXTANT TIY PROGRAM (MINDFUL YOGA THERAPY) ADAPTED FOR VETERAN WOMEN WITH MST IN CONCURRENT PSYCHOTHERAPY. MAIN OUTCOME MEASURES: ATTRITION AND ATTENDANCE; QUALITATIVE EXIT INTERVIEW; VALIDATED SELF-REPORT MEASURE OF NEGATIVE AFFECT PRE/POST EACH YOGA CLASS, AND SYMPTOM SEVERITY ASSESSMENTS AND SURVEYS BEFORE (T1; TIME 1) AND AFTER THE YOGA PROGRAM (T2; TIME 2). RESULTS: FEASIBILITY WAS DEMONSTRATED AND WOMEN REPORTED TIY WAS ACCEPTABLE. IN QUALITATIVE INTERVIEWS, WOMEN REPORTED IMPROVED SYMPTOM SEVERITY, DIET, EXERCISE, ALCOHOL USE, SLEEP, AND PAIN; REDUCED MEDICATION USE; AND THEMES RELATED TO STRESS REDUCTION, MINDFULNESS, AND SELF-COMPASSION. REGARDING QUANTITATIVE CHANGE, RESULTS SUGGEST ACUTE REDUCTIONS IN NEGATIVE AFFECT FOLLOWING YOGA SESSIONS ACROSS PARTICIPANTS, AS WELL AS IMPROVED AFFECT DYSREGULATION, SHAME, AND MINDFULNESS T1 TO T2. CONCLUSIONS: TIY IS BOTH FEASIBLE AND ACCEPTABLE TO VETERAN WOMEN MST SURVIVORS IN ONE SPECIFIC VET CENTER, WITH PERCEIVED BEHAVIORAL HEALTH BENEFITS. RESULTS SUGGEST TIY MAY TARGET PSYCHOSOCIAL MECHANISMS IMPLICATED IN HEALTH BEHAVIOR CHANGE (STRESS REDUCTION, MINDFULNESS, AFFECT REGULATION, SHAME). FORMAL RESEARCH SHOULD BE CONDUCTED TO CONFIRM THESE QI PROJECT RESULTS.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
19  108  56 A PILOT RANDOMIZED CONTROLLED TRIAL OF THE YOGA OF AWARENESS PROGRAM IN THE MANAGEMENT OF FIBROMYALGIA. A MOUNTING BODY OF LITERATURE RECOMMENDS THAT TREATMENT FOR FIBROMYALGIA (FM) ENCOMPASS MEDICATIONS, EXERCISE AND IMPROVEMENT OF COPING SKILLS. HOWEVER, THERE IS A SIGNIFICANT GAP IN DETERMINING AN EFFECTIVE COUNTERPART TO PHARMACOTHERAPY THAT INCORPORATES BOTH EXERCISE AND COPING. THE AIM OF THIS RANDOMIZED CONTROLLED TRIAL WAS TO EVALUATE THE EFFECTS OF A COMPREHENSIVE YOGA INTERVENTION ON FM SYMPTOMS AND COPING. A SAMPLE OF 53 FEMALE FM PATIENTS WERE RANDOMIZED TO THE 8-WEEK YOGA OF AWARENESS PROGRAM (GENTLE POSES, MEDITATION, BREATHING EXERCISES, YOGA-BASED COPING INSTRUCTIONS, GROUP DISCUSSIONS) OR TO WAIT-LISTED STANDARD CARE. DATA WERE ANALYZED BY INTENTION TO TREAT. AT POST-TREATMENT, WOMEN ASSIGNED TO THE YOGA PROGRAM SHOWED SIGNIFICANTLY GREATER IMPROVEMENTS ON STANDARDIZED MEASURES OF FM SYMPTOMS AND FUNCTIONING, INCLUDING PAIN, FATIGUE, AND MOOD, AND IN PAIN CATASTROPHIZING, ACCEPTANCE, AND OTHER COPING STRATEGIES. THIS PILOT STUDY PROVIDES PROMISING SUPPORT FOR THE POTENTIAL BENEFITS OF A YOGA PROGRAM FOR WOMEN WITH FM.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
20 2361  36 VIVEKANANDA YOGA PROGRAM FOR PATIENTS WITH ADVANCED LUNG CANCER AND THEIR FAMILY CAREGIVERS. BACKGROUND: THE PRIMARY PURPOSE OF THIS STUDY WAS TO ESTABLISH THE FEASIBILITY OF A COUPLE-BASED VIVEKANANDA YOGA (VKC) INTERVENTION IN LUNG CANCER PATIENTS AND CAREGIVERS. SECONDLY, WE EXAMINED PRELIMINARY EFFICACY REGARDING QUALITY OF LIFE (QOL) OUTCOMES. METHOD: IN THIS SINGLE-ARM FEASIBILITY TRIAL, PATIENTS WITH LUNG CANCER UNDERGOING RADIOTHERAPY AND THEIR CAREGIVERS PARTICIPATED IN A 15-SESSION VKC PROGRAM THAT FOCUSED ON THE INTERCONNECTEDNESS OF THE DYAD. WE ASSESSED PRE-AND POST-INTERVENTION LEVELS OF FATIGUE, SLEEP DISTURBANCES, PSYCHOLOGICAL DISTRESS, OVERALL QOL, SPIRITUALITY, AND RELATIONAL CLOSENESS. WE TRACKED FEASIBILITY DATA, AND PARTICIPANTS COMPLETED PROGRAM EVALUATIONS. RESULTS: WE APPROACHED 28 ELIGIBLE DYADS OF WHICH 15 (53%) CONSENTED AND 9 (60%) COMPLETED THE INTERVENTION. PATIENTS (MEAN AGE = 73 YEARS, 63% FEMALE, ALL STAGE III) AND CAREGIVERS (MEAN AGE = 62 YEARS, 38% FEMALE, 63% SPOUSES) COMPLETED A MEAN OF 10 SESSIONS AND 95.5% OF THEM RATED THE PROGRAM AS VERY USEFUL. PAIRED T TESTS REVEALED A SIGNIFICANT INCREASE IN PATIENTS' MENTAL HEALTH (D = 0.84; P = .04) AND A SIGNIFICANT DECREASE IN CAREGIVERS' SLEEP DISTURBANCES (D = 1.44; P = .02). ALTHOUGH NOT STATISTICALLY SIGNIFICANT, FOR PATIENTS, EFFECT SIZES FOR CHANGE SCORES WERE MEDIUM FOR BENEFIT FINDING AND SMALL FOR DISTRESS (D = 0.65 AND 0.37, RESPECTIVELY). FOR CAREGIVERS, MEDIUM EFFECTS WERE FOUND FOR IMPROVEMENT IN PHYSICAL FUNCTIONING (D = 0.50). CONCLUSION: THIS NOVEL SUPPORTIVE CARE PROGRAM APPEARS TO BE SAFE, FEASIBLE, ACCEPTABLE, AND SUBJECTIVELY USEFUL FOR LUNG CANCER PATIENTS AND THEIR CAREGIVERS AND LENDS SUPPORT FOR FURTHER STUDY.	2015