1  625 131 DIABETIC YOGA PROTOCOL IMPROVES GLYCEMIC, ANTHROPOMETRIC AND LIPID LEVELS IN HIGH RISK INDIVIDUALS FOR DIABETES: A RANDOMIZED CONTROLLED TRIAL FROM NORTHERN INDIA. PURPOSE: TO STUDY THE EFFECTIVENESS OF DIABETIC YOGA PROTOCOL (DYP) AGAINST MANAGEMENT OF CARDIOVASCULAR RISK PROFILE IN A HIGH-RISK COMMUNITY FOR DIABETES, FROM CHANDIGARH, INDIA. METHODS: THE STUDY WAS A RANDOMIZED CONTROLLED TRIAL, CONDUCTED AS A SUB STUDY OF THE PAN INDIA TRIAL NIYANTRITA MADHUMEHA BHARATH (NMB). THE COHORT WAS IDENTIFIED THROUGH THE INDIAN DIABETES RISK SCORING (IDRS) (>/= 60) AND A TOTAL OF 184 INDIVIDUALS WERE RANDOMIZED INTO INTERVENTION (N = 91) AND CONTROL GROUPS (N = 93). THE DYP GROUP UNDERWENT THE SPECIFIC DYP TRAINING WHEREAS THE CONTROL GROUP FOLLOWED THEIR DAILY REGIMEN. THE STUDY OUTCOMES INCLUDED CHANGES IN GLYCEMIC AND LIPID PROFILE. ANALYSIS WAS DONE UNDER INTENT-TO-TREAT PRINCIPLE. RESULTS: THE 3 MONTHS DYP PRACTICE SHOWED DIVERSE RESULTS SHOWING GLYCEMIC AND LIPID PROFILE OF THE HIGH RISK INDIVIDUALS. THREE MONTHS OF DYP INTERVENTION WAS FOUND TO SIGNIFICANTLY REDUCE THE LEVELS OF POST-PRANDIAL GLUCOSE LEVELS (P = 0.035) AND LDL-C LEVELS (P = 0.014) AND WAIST CIRCUMFERENCE (P = 0.001). CONCLUSION: THE FINDINGS INDICATE THAT THE DYP INTERVENTION COULD IMPROVE THE METABOLIC STATUS OF THE HIGH-DIABETES-RISK INDIVIDUALS WITH RESPECT TO THEIR GLUCOSE TOLERANCE AND LIPID LEVELS, PARTIALLY EXPLAINED BY THE REDUCTION IN ABDOMINAL OBESITY. THE STUDY HIGHLIGHTS THE POTENTIAL ROLE OF YOGA INTERVENTION IN REAL TIME IMPROVEMENT OF CARDIOVASCULAR PROFILE IN A HIGH DIABETES RISK COHORT. TRIAL REGISTRATION: CTRI, CTRI/2018/03/012804. REGISTERED 01 MARCH 2018-RETROSPECTIVELY REGISTERED, HTTP://WWW.CTRI.NIC.IN/ CTRI/2018/03/012804.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
2  685  34 EFFECT OF AN INTEGRATED NATUROPATHY AND YOGA PROGRAM ON LONG-TERM GLYCEMIC CONTROL IN TYPE 2 DIABETES MELLITUS PATIENTS: A PROSPECTIVE COHORT STUDY. AIM: LIFESTYLE IS AN IMPORTANT RISK FACTOR FOR INCREASING THE PREVALENCE OF DIABETES IN THE INDIAN POPULATION. IN THIS STUDY, WE EVALUATE THE EFFECTS OF NATUROPATHY TREATMENT, SALT-RESTRICTED LOW-CALORIE DIETS, AND YOGA IN LONG-TERM GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. METHODS: IN THIS PROSPECTIVE, LONGITUDINAL, TWO-ARM COHORT STUDY, PATIENTS WITH TYPE 2 DIABETES MELLITUS REFERRED FROM A TERTIARY CARE CENTER UNDERGOING A 3-MONTH RESIDENTIAL NATUROPATHY TREATMENT WERE COMPARED WITH THOSE UNDERGOING ONLY CONVENTIONAL MANAGEMENT ON GLYCEMIC CONTROL. BOTH FASTING AND POSTPRANDIAL BLOOD GLUCOSE (PPBG) LEVELS WERE ASSESSED AT BASELINE, 3 MONTHS FOLLOWING INTERVENTION, AT 6 MONTHS, AND 12 MONTHS FROM THE STUDY START. DATA WERE ANALYZED USING REPEATED-MEASURES ANOVA WITH POST HOC BONFERRONI CORRECTION. RESULTS: NATUROPATHY AND YOGA INTERVENTION SIGNIFICANTLY REDUCED PPBG LEVELS (P < 0.001), GLYCATED HEMOGLOBIN LEVELS (P < 0.001), AND REDUCED REQUIREMENT FOR ANTIDIABETIC MEDICATIONS (P < 0.008) IN THE INTERVENTION GROUP COMPARED TO CONTROLS. THE EFFECTS WERE MORE PROFOUND IMMEDIATELY FOLLOWING INTERVENTION AND LASTED UP TO 6 MONTHS FROM THE START OF THE STUDY. CONCLUSION: THE RESULTS SUGGEST BENEFIT WITH AN INTENSIVE RESIDENTIAL NATUROPATHY-BASED LIFESTYLE INTERVENTION PROGRAM. RANDOMIZED CONTROLLED TRIALS ARE NEEDED TO FURTHER VALIDATE THE FINDINGS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
3  279  33 ADHERENCE AND RETENTION OF AFRICAN AMERICANS IN A RANDOMIZED CONTROLLED TRIAL WITH A YOGA-BASED INTERVENTION: THE EFFECTS OF HEALTH PROMOTING PROGRAMS ON CARDIOVASCULAR DISEASE RISK STUDY. OBJECTIVES: SEDENTARY LIFESTYLE IS A RISK FACTOR FOR CARDIOVASCULAR DISEASE (CVD). FEW ALTERNATIVE LIFESTYLE INTERVENTIONS, SUCH AS YOGA PRACTICE, FOCUS ON AFRICAN AMERICANS (AA), THE POPULATION MOST VULNERABLE TO CVD. OUR OBJECTIVE IS TO COMPARE THE RETENTION AND ADHERENCE RATES BETWEEN YOGA, WALKING, AND HEALTH EDUCATION INTERVENTIONS WHILE PROVIDING INFORMATION ABOUT THE ACCEPTANCE OF VARIOUS YOGA REGIMENS. DESIGN: THREE HUNDRED SEVENTY-FIVE AA PARTICIPANTS WERE RECRUITED EXCLUSIVELY FROM AN ACTIVE COHORT STUDY AND RANDOMIZED INTO A 48-WEEK STUDY (24 WEEKS INTERVENTION, 24 WEEKS FOLLOW-UP) WITH 5 HEALTH PROMOTION INTERVENTIONS: HIGH FREQUENCY YOGA, MODERATE FREQUENCY YOGA, LOW FREQUENCY YOGA, GUIDED WALKING, AND HEALTH EDUCATION. IN ADDITION TO EXAMINING THE SEPARATE YOGA INTERVENTIONS, A POOLED YOGA INTERVENTION IS CONSIDERED FOR COMPARISON TO GUIDED WALKING AND HEALTH EDUCATION. PARTICIPANT RETENTION, ADHERENCE, AND VITALS WERE MONITORED AT EACH INTERVENTION SESSION. PARTICIPANTS WERE ALSO SCHEDULED FOR FOUR CLINIC VISITS THROUGHOUT THE STUDY WHERE BLOOD PANELS, HEALTH BEHAVIOR, AND MEDICATION SURVEYS WERE ADMINISTERED. RESULTS: OF THE 375 PARTICIPANTS RECRUITED, 31.7% DID NOT COMPLETE THE STUDY. AT BASELINE, IN BOTH THE GUIDED WALKING GROUP AND THE HIGH FREQUENCY YOGA GROUP, THERE WERE SIGNIFICANT DIFFERENCES BETWEEN THOSE WHO COMPLETED THE STUDY AND THOSE WHO DID NOT. ALTHOUGH INTERVENTION RETENTION IN THE POOLED YOGA PROGRAM (78.3%) WAS HIGHER COMPARED TO THE WALKING (60%) AND EDUCATION PROGRAMS (74.3%) (P = 0.007), DIFFERENCES IN POST-INTERVENTION RETENTION WAS NOT SIGNIFICANT. MEDIAN ADHERENCE RATES FOR THE POOLED YOGA PROGRAM EXCEEDED RATES FOR GUIDED WALKING AND EDUCATION WITH MODERATE FREQUENCY YOGA OUT PERFORMING HIGH AND LOW FREQUENCY YOGA. CONCLUSION: STUDY-DEFINED RETENTION SUCCESS RATES WERE NOT REACHED BY ALL HEALTH PROMOTION PROGRAMS. HOWEVER, RETENTION AND ADHERENCE RATES FOR THE POOLED YOGA PROGRAM SHOW THAT OLDER AFRICAN AMERICANS ARE RECEPTIVE TO PARTICIPATING IN YOGA-BASED HEALTH PROMOTION PRACTICES.	2020	
                                                                                                                                                                                                                                                                                                               
4  926  50 EFFECTIVENESS OF YOGA LIFESTYLE ON LIPID METABOLISM IN A VULNERABLE POPULATION-A COMMUNITY BASED MULTICENTER RANDOMIZED CONTROLLED TRIAL. BACKGROUND: DYSLIPIDEMIA POSES A HIGH RISK FOR CARDIOVASCULAR DISEASE AND STROKE IN TYPE 2 DIABETES (T2DM). THERE ARE NO STUDIES ON THE IMPACT OF A VALIDATED INTEGRATED YOGA LIFESTYLE PROTOCOL ON LIPID PROFILES IN A HIGH-RISK DIABETES POPULATION. METHODS: HERE, WE REPORT THE RESULTS OF LIPID PROFILE VALUES OF 11,254 (YOGA 5932 AND CONTROL 5322) ADULTS (20-70 YEARS) OF BOTH GENDERS WITH HIGH RISK (>/=60 ON INDIAN DIABETES RISK SCORE) FOR DIABETES FROM A NATIONWIDE RURAL AND URBAN COMMUNITY-BASED TWO GROUP (YOGA AND CONVENTIONAL MANAGEMENT) CLUSTER RANDOMIZED CONTROLLED TRIAL. THE YOGA GROUP PRACTICED A VALIDATED INTEGRATED YOGA LIFESTYLE PROTOCOL (DYP) IN NINE DAY CAMPS FOLLOWED BY DAILY ONE-HOUR PRACTICE. BIOCHEMICAL PROFILING INCLUDED GLYCATED HEMOGLOBIN AND LIPID PROFILES BEFORE AND AFTER THREE MONTHS. RESULTS: THERE WAS A SIGNIFICANT DIFFERENCE BETWEEN GROUPS (P < 0.001 ANCOVA) WITH IMPROVED SERUM TOTAL CHOLESTEROL, TRIGLYCERIDES, LOW-DENSITY LIPOPROTEIN, AND HIGH-DENSITY LIPOPROTEIN IN THE YOGA GROUP COMPARED TO THE CONTROL GROUP. FURTHER, THE REGULATORY EFFECT OF YOGA WAS NOTED WITH A SIGNIFICANT DECREASE OR INCREASE IN THOSE WITH HIGH OR LOW VALUES OF LIPIDS, RESPECTIVELY, WITH MARGINAL OR NO CHANGE IN THOSE WITHIN THE NORMAL RANGE. CONCLUSION: YOGA LIFESTYLE IMPROVES AND REGULATES (LOWERED IF HIGH, INCREASED IF LOW) THE BLOOD LIPID LEVELS IN BOTH GENDERS OF PREDIABETIC AND DIABETIC INDIVIDUALS IN BOTH RURAL AND URBAN INDIAN COMMUNITIES.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
5 2867  30 YOGA-BASED LIFESTYLE TREATMENT AND COMPOSITE TREATMENT GOALS IN TYPE 2 DIABETES IN A RURAL SOUTH INDIAN SETUP- A RETROSPECTIVE STUDY. THIS MULTICENTRE RETROSPECTIVE STUDY EXAMINED THE EFFECTS OF ADJUNCT YOGA-TREATMENT IN ACHIEVING COMPOSITE CARDIOVASCULAR GOALS FOR TYPE 2 DIABETES (T2D), SET FORTH BY THE AMERICAN DIABETES ASSOCIATION (ADA) IN RURAL INDIAN SETTINGS. RECORDS WERE EXTRACTED FOR 146 T2D PATIENTS, AGED >/=20-70 YEARS, AND TREATED UNDER THE "APOLLO TOTAL HEALTH PROGRAMME" FOR RURAL DIABETES MANAGEMENT, FOR THE PERIOD APRIL 2016 TO NOVEMBER 2016. THE STUDY COHORT COMPRISED OF TWO TREATMENT GROUPS (N = 73 EACH); NON-YOGA GROUP (STANDARD OF CARE) AND YOGA GROUP (ADJUNCT YOGA-TREATMENT). PROPENSITY SCORE MATCHING WAS APPLIED BETWEEN THE STUDY GROUPS TO DEFINE THE COHORT. COMPOSITE CARDIOVASCULAR SCORES WERE BASED ON THE COMBINATION OF INDIVIDUAL ADA GOALS; A1C < 7%, BLOOD PRESSURE (BP) < 140/90 MMHG, STRINGENT BP (<130/80 MMHG) AND LIPID, LDL-C < 100 MG/DL [RISK FACTOR FOR ATHEROSCLEROTIC CARDIOVASCULAR DISEASE]. LOGISTIC REGRESSION WAS USED TO COMPARE BETWEEN THE TWO TREATMENT GROUPS. COMPARED TO STANDARD OF CARE, ADJUNCT YOGA-TREATMENT WAS FOUND TO SIGNIFICANTLY FACILITATE THE ATTAINMENT OF ADA COMPOSITE SCORE BY 8-FOLD; A1C, ~2-FOLD; LDL-C, ~2-FOLD; BP < 140/90 MMHG AND <130/80 MMHG BY ~8-AND ~6-FOLD RESPECTIVELY. THIS STUDY PROVIDES THE FIRST EVIDENCE FOR SIGNIFICANT EFFICACY OF ADJUNCT YOGA-TREATMENT FOR THE ATTAINMENT OF FAVOURABLE TREATMENT GOALS FOR T2D IN RURAL INDIAN SETTINGS. CLINICAL TRIAL REGISTRATION NUMBER: CTRI/2020/02/0232790.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
6 2733  26 YOGA PARTICIPATION AND ALL-CAUSE MORTALITY: NATIONAL PROSPECTIVE COHORT STUDY. BACKGROUND: THE RELATIVELY FEW STUDIES EXAMINING THE EFFECT OF YOGA PARTICIPATION ON CHRONIC DISEASE COME FROM SMALL, SHORT-TERM STUDIES. AS A RESULT, THE PURPOSE OF THIS STUDY WAS TO PROSPECTIVELY EXAMINE THE EFFECTS OF YOGA PARTICIPATION ON ALL-CAUSE MORTALITY IN A LARGE NATIONALLY REPRESENTATIVE STUDY WITH A RELATIVELY LONG FOLLOW-UP PERIOD (UP TO 12 YEAR FOLLOW-UP). METHODS: DATA FROM THE 1999-2006 NATIONAL HEALTH & NUTRITION EXAMINATION SURVEY WERE USED, WITH FOLLOW-UP THROUGH 2011. YOGA PARTICIPATION WAS SELF-REPORTED, WITH PARTICIPANT IDENTIFICATION LINKED TO DEATH CERTIFICATE DATA FROM THE NATIONAL DEATH INDEX TO ASCERTAIN MORTALITY STATUS. RESULTS: IN THE ANALYZED SAMPLE, WHICH INCLUDED 22,598 ADULT PARTICIPANTS, 240 PARTICIPANTS ENGAGED IN YOGA AND 3176 DIED OVER THE FOLLOW-UP PERIOD; THE MEDIAN FOLLOW-UP PERIOD WAS 102 MONTHS (8.5 YEARS). IN AN UNADJUSTED COX HAZARD MODEL, THOSE ENGAGING IN YOGA, COMPARED TO THOSE NOT ENGAGING IN YOGA, HAD A 63% REDUCED RISK OF PREMATURE ALL-CAUSE MORTALITY (HR=0.37; 95% CI: 0.18-0.74; P=.006). HOWEVER, AFTER ADJUSTING FOR AGE, THE ASSOCIATION WAS ATTENUATED AND NO LONGER STATISTICALLY SIGNIFICANT (HR(ADJUSTED)=0.82; 95% CI: 0.39-1.72; P=.60). CONCLUSION: IN CONCLUSION, YOGA PARTICIPATION WAS NOT SIGNIFICANTLY ASSOCIATED WITH REDUCED ALL-CAUSE MORTALITY RISK IN AN ADJUSTED MODEL.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
7 2072  35 THE EFFECT OF A SIX-WEEK PROGRAM OF YOGA AND MEDITATION ON BRACHIAL ARTERY REACTIVITY: DO PSYCHOSOCIAL INTERVENTIONS AFFECT VASCULAR TONE? BACKGROUND: CHRONIC STRESS IS ESTIMATED TO INCREASE THE RISK OF CARDIOVASCULAR (CV) EVENTS TWO-FOLD. ALTHOUGH STRESS REDUCTION HAS BEEN LINKED TO A REDUCTION IN CV EVENTS, LITTLE IS KNOWN REGARDING ITS EXACT MECHANISM OF BENEFIT. HYPOTHESIS: YOGA AND MEDITATION WILL IMPROVE PARAMETERS OF ENDOTHELIAL FUNCTION. METHODS: WE EXAMINED THE EFFECTS OF YOGA AND MEDITATION ON HEMODYNAMIC AND LABORATORY PARAMETERS AS WELL AS ON ENDOTHELIAL FUNCTION IN A 6-WEEK PILOT STUDY. SYSTOLIC AND DIASTOLIC BLOOD PRESSURES, HEART RATE, BODY MASS INDEX (BMI), FASTING GLUCOSE, LIPIDS, HS C-REACTIVE PROTEIN (CRP), AND ENDOTHELIAL FUNCTION (AS ASSESSED BY BRACHIAL ARTERY REACTIVITY) WERE ALL STUDIED AT BASELINE AND AFTER 6 WEEKS OF YOGA PRACTICE. RESULTS: A COURSE IN YOGA AND MEDITATION WAS GIVEN TO THE SUBJECTS FOR 1.5 H THREE TIMES WEEKLY FOR 6 WEEKS AND SUBJECTS WERE INSTRUCTED TO CONTINUE THEIR EFFORTS AT HOME. THIS PROSPECTIVE COHORT STUDY INCLUDED 33 SUBJECTS (MEAN AGE 55 +/- 11 YEARS) BOTH WITH (30%) AND WITHOUT (70%) ESTABLISHED CORONARY ARTERY DISEASE (CAD). THERE WERE SIGNIFICANT REDUCTIONS IN BLOOD PRESSURE, HEART RATE, AND BMI IN THE TOTAL COHORT WITH YOGA. NONE OF THE LABORATORY PARAMETERS CHANGED SIGNIFICANTLY WITH YOGA. FOR THE TOTAL COHORT THERE WAS NO SIGNIFICANT IMPROVEMENT IN ENDOTHELIAL-DEPENDENT VASODILATATION WITH YOGA TRAINING AND MEDITATION COMPARED WITH BASELINE (16.7% RELATIVE IMPROVEMENT FROM 7.2-8.4%; P = 0.3). IN THE GROUP WITH CAD, ENDOTHELIAL-DEPENDENT VASODILATATION IMPROVED 69% WITH YOGA TRAINING (6.38-10.78%; P = 0.09). CONCLUSION: YOGA AND MEDITATION APPEAR TO IMPROVE ENDOTHELIAL FUNCTION IN SUBJECTS WITH CAD.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
8  247  43 A YOGA INTERVENTION FOR TYPE 2 DIABETES RISK REDUCTION: A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: TYPE 2 DIABETES IS A MAJOR HEALTH PROBLEM IN MANY COUNTRIES INCLUDING INDIA. YOGA MAY BE AN EFFECTIVE TYPE 2 DIABETES PREVENTION STRATEGY IN INDIA, PARTICULARLY GIVEN ITS CULTURAL FAMILIARITY. METHODS: THIS WAS A PARALLEL, RANDOMIZED CONTROLLED PILOT STUDY TO COLLECT FEASIBILITY AND PRELIMINARY EFFICACY DATA ON YOGA FOR DIABETES RISK FACTORS AMONG PEOPLE AT HIGH RISK OF DIABETES. PRIMARY OUTCOMES INCLUDED: CHANGES IN BMI, WAIST CIRCUMFERENCE, FASTING BLOOD GLUCOSE, POSTPRANDIAL BLOOD GLUCOSE, INSULIN, INSULIN RESISTANCE, BLOOD PRESSURE, AND CHOLESTEROL. WE ALSO LOOKED AT MEASURES OF PSYCHOLOGICAL WELL-BEING INCLUDING CHANGES IN DEPRESSION, ANXIETY, POSITIVE AND NEGATIVE AFFECT AND PERCEIVED STRESS. FORTY-ONE PARTICIPANTS WITH ELEVATED FASTING BLOOD GLUCOSE IN BANGALORE, INDIA WERE RANDOMIZED TO EITHER YOGA (N = 21) OR A WALKING CONTROL (N = 20). PARTICIPANTS WERE ASKED TO EITHER ATTEND YOGA CLASSES OR COMPLETE MONITORED WALKING 3-6 DAYS PER WEEK FOR EIGHT WEEKS. RANDOMIZATION AND ALLOCATION WAS PERFORMED USING COMPUTER-GENERATED RANDOM NUMBERS AND GROUP ASSIGNMENTS DELIVERED IN SEALED, OPAQUE ENVELOPES GENERATED BY OFF-SITE STUDY STAFF. DATA WERE ANALYZED BASED ON INTENTION TO TREAT. RESULTS: THIS STUDY WAS FEASIBLE IN TERMS OF RECRUITMENT, RETENTION AND ADHERENCE. IN ADDITION, YOGA PARTICIPANTS HAD SIGNIFICANTLY GREATER REDUCTIONS IN WEIGHT, WAIST CIRCUMFERENCE AND BMI VERSUS CONTROL (WEIGHT -0.8 +/- 2.1 VS. 1.4 +/- 3.6, P = 0.02; WAIST CIRCUMFERENCE -4.2 +/- 4.8 VS. 0.7 +/- 4.2, P < 0.01; BMI -0.2 +/- 0.8 VS. 0.6 +/- 1.6, P = 0.05). THERE WERE NO BETWEEN GROUP DIFFERENCES IN FASTING BLOOD GLUCOSE, POSTPRANDIAL BLOOD GLUCOSE, INSULIN RESISTANCE OR ANY OTHER FACTORS RELATED TO DIABETES RISK OR PSYCHOLOGICAL WELL-BEING. THERE WERE SIGNIFICANT REDUCTIONS IN SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, TOTAL CHOLESTEROL, ANXIETY, DEPRESSION, NEGATIVE AFFECT AND PERCEIVED STRESS IN BOTH THE YOGA INTERVENTION AND WALKING CONTROL OVER THE COURSE OF THE STUDY. CONCLUSION: AMONG INDIANS WITH ELEVATED FASTING BLOOD GLUCOSE, WE FOUND THAT PARTICIPATION IN AN 8-WEEK YOGA INTERVENTION WAS FEASIBLE AND RESULTED IN GREATER WEIGHT LOSS AND REDUCTION IN WAIST CIRCUMFERENCE WHEN COMPARED TO A WALKING CONTROL. YOGA OFFERS A PROMISING LIFESTYLE INTERVENTION FOR DECREASING WEIGHT-RELATED TYPE 2 DIABETES RISK FACTORS AND POTENTIALLY INCREASING PSYCHOLOGICAL WELL-BEING. TRIAL REGISTRATION: CLINICALTRIALS.GOV IDENTIFIED NCT00090506.	2014	

9 1270  38 FRAMINGHAM RISK SCORE AND ESTIMATED 10-YEAR CARDIOVASCULAR DISEASE RISK REDUCTION BY A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION. OBJECTIVE: THE AIM OF THIS STUDY WAS TO EVALUATE THE EFFICACY OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION PROGRAM IN LOWERING FRAMINGHAM RISK SCORE (FRS) AND ESTIMATED 10-YEAR CARDIOVASCULAR RISK. METHODS: THIS WAS A SINGLE-ARM, PRE-POST INTERVENTIONAL STUDY INCLUDING DATA FROM A HISTORICAL COHORT WITH LOW TO MODERATE RISK FOR CARDIOVASCULAR DISEASE (CVD). IT WAS CONDUCTED IN A TERTIARY-CARE HOSPITAL. PARTICIPANTS WITH LOW (0 OR 1 CVD RISK FACTORS) TO MODERATELY HIGH RISK (10-YEAR RISK BETWEEN 10% AND 20% AND TWO OR MORE CVD RISK FACTORS) WERE INCLUDED. PARTICIPANTS WITH PREVIOUSLY DIAGNOSED CVD, DEFINED AS A HISTORY OF MYOCARDIAL INFARCTION, CONGESTIVE HEART FAILURE, OR CEREBROVASCULAR ACCIDENT, WERE EXCLUDED FROM THE ANALYSIS. HOWEVER, THOSE WITH CONTROLLED HYPERTENSION WERE INCLUDED. INTERVENTION INCLUDED A PRETESTED SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION, WHICH INCLUDED ASANAS (PHYSICAL POSTURES), PRANAYAMA (BREATHING EXERCISES), MEDITATION, RELAXATION TECHNIQUES, STRESS MANAGEMENT, GROUP SUPPORT, NUTRITION AWARENESS PROGRAM, AND INDIVIDUALIZED ADVICE. THE INTERVENTION WAS FOR 10 DAYS, SPREAD OVER 2 WEEKS. HOWEVER, PARTICIPANTS WERE ENCOURAGED TO INCLUDE IT IN THEIR DAY-TO-DAY LIFE. OUTCOMES INCLUDED CHANGES IN FRS, AND ESTIMATED 10-YEAR CVD RISK FROM BASELINE TO WEEK 2. A GENDER-BASED SUBGROUP ANALYSIS WAS ALSO DONE, AND CORRELATION BETWEEN CHANGES IN FRS AND CARDIOVASCULAR RISK FACTORS WAS EVALUATED. RESULTS: DATA FOR 554 SUBJECTS WERE SCREENED, AND 386 SUBJECTS (252 FEMALES) WERE INCLUDED IN THE ANALYSIS. THERE WAS A SIGNIFICANT REDUCTION IN FRS (P < 0.001) AND ESTIMATED 10-YEAR CARDIOVASCULAR RISK (P < 0.001) FOLLOWING THE SHORT-TERM YOGA-BASED INTERVENTION. THERE WAS A STRONG POSITIVE CORRELATION BETWEEN REDUCTION IN FRS AND SERUM TOTAL CHOLESTEROL (R = 0.60; P < 0.001). THERE WAS A MODERATE POSITIVE CORRELATION BETWEEN REDUCTION IN FRS AND LOW-DENSITY LIPOPROTEIN CHOLESTEROL (R = 0.58; P < 0.001), AND A WEAK BUT POSITIVE CORRELATION BETWEEN REDUCTION IN FRS AND TRIGLYCERIDES (R = 0.26; P </= 0.001), SERUM VERY-LOW-DENSITY LIPOPROTEIN CHOLESTEROL (R = 0.29; P < 0.001), AND SYSTOLIC BLOOD PRESSURE (R = 0.20; P </= 0.001). CONCLUSIONS: THIS YOGA-BASED LIFESTYLE INTERVENTION PROGRAM SIGNIFICANTLY REDUCED THE CVD RISK, AS SHOWN BY LOWERED FRS AND ESTIMATED 10-YEAR CVD RISK. FURTHER TESTING OF THIS PROMISING INTERVENTION IS WARRANTED IN THE LONG TERM.	2017	
          
10 2834  34 YOGA'S EFFECT ON INFLAMMATORY BIOMARKERS AND METABOLIC RISK FACTORS IN A HIGH RISK POPULATION - A CONTROLLED TRIAL IN PRIMARY CARE. BACKGROUND: YOGA CAN REDUCE BLOOD PRESSURE AND HAS ALSO BEEN SUGGESTED TO REDUCE INFLAMMATORY BIOMARKERS AND METABOLIC RISK FACTORS FOR CARDIOVASCULAR DISEASES (CVDS). WE AIMED TO ASSESS THE BENEFIT OF TWO YOGA INTERVENTIONS ON INFLAMMATORY BIOMARKERS AND METABOLIC RISK FACTORS IN A HIGH RISK POPULATION IN PRIMARY CARE. METHODS: ADULT PATIENTS FROM A HEALTH CARE CENTER IN SWEDEN, WITH DIAGNOSED HYPERTENSION, WERE INVITED TO UNDERGO A BASELINE CHECK AT THE HEALTH CARE CENTER. BASELINE CHECK INCLUDED STANDARDIZED BLOOD PRESSURE MEASUREMENT, BMI AND WEIGHT CIRCUMFERENCE MEASUREMENTS, BLOOD SAMPLING (HS-CRP, IL-6, FP-GLUCOSE, HBA1C, CHOLESTEROL, TG, LDL AND HDL) AND A QUESTIONNAIRE ON SELF-RATED QUALITY OF LIFE (WHOQOL-BREF). THERE WERE THREE GROUPS: 1) YOGA CLASS WITH YOGA INSTRUCTOR; 2) YOGA AT HOME; AND 3) A CONTROL GROUP. IN TOTAL, 83 PATIENTS WERE INCLUDED AND MATCHED AT THE GROUP LEVEL FOR SYSTOLIC BLOOD PRESSURE. A MAJORITY OF THE PATIENTS (92 %) WERE ON ANTIHYPERTENSIVE MEDICATION, WHICH THEY WERE REQUESTED NOT TO CHANGE DURING THE STUDY. AFTER 12 WEEKS OF INTERVENTION, THE ASSESSMENTS WERE PERFORMED AGAIN. RESULTS: WE RECORDED NO EVIDENCE THAT YOGA ALTERED INFLAMMATORY BIOMARKERS OR METABOLIC RISK FACTORS IN OUR STUDY POPULATION. A TOTAL OF 49 PARTICIPANTS (59 %) MET THE CRITERIA FOR METABOLIC SYNDROME. CONCLUSION: THE YOGA INTERVENTIONS PERFORMED IN OUR STUDY DID NOT AFFECT INFLAMMATORY BIOMARKERS OR METABOLIC RISK FACTORS ASSOCIATED WITH CVD IN THE STUDY POPULATION OF PRIMARY CARE PATIENTS WITH HYPERTENSION. FURTHER RANDOMIZED TRIALS ARE NEEDED TO ELUCIDATE THE EFFECTS OF YOGA ON CVD RISK FACTORS IN THIS PARTICULAR GROUP. TRAIL REGISTRATION: NCT01302535 , FEBRUARY 22, 2011.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
11 1658  28 MUSCULOSKELETAL PAIN ASSOCIATED WITH RECREATIONAL YOGA PARTICIPATION: A PROSPECTIVE COHORT STUDY WITH 1-YEAR FOLLOW-UP. BACKGROUND: YOGA IS A POPULAR COMPLEMENTARY THERAPY FOR MUSCULOSKELETAL PAIN. THERE ARE FEW STUDIES HOWEVER, THAT HAVE EXAMINED THE RISKS OF RECREATIONAL PARTICIPATION FOR CAUSING MUSCULOSKELETAL PAIN. OBJECTIVES: TO EXAMINE THE RELATIONSHIP BETWEEN MUSCULOSKELETAL PAIN AND RECREATIONAL YOGA PARTICIPATION. METHODS: THIS WAS A PROSPECTIVE COHORT STUDY WITH ONE-YEAR FOLLOW-UP. DATA WERE COLLECTED VIA ELECTRONIC QUESTIONNAIRES, ONE YEAR APART. OUTCOMES INCLUDED INCIDENCE AND IMPACT OF PAIN CAUSED BY YOGA AND PREVALENCE OF PAIN CAUSED, EXACERBATED, UNAFFECTED, AND IMPROVED BY YOGA. PREDICTORS INCLUDED AGE, EXPERIENCE, HOURS OF PARTICIPATION, AND INTENSITY OF PARTICIPATION. RESULTS: THE FINAL SAMPLE INCLUDED 354 PARTICIPANTS FROM TWO SUBURBAN YOGA STUDIOS. THE INCIDENCE RATE OF PAIN CAUSED BY YOGA WAS 10.7%. MORE THAN ONE-THIRD OF INCIDENT CASES RESULTED IN LOST YOGA PARTICIPATION TIME AND/OR SYMPTOMS LASTING MORE THAN 3 MONTHS. NONE OF THE RISK FACTORS AT BASELINE INCREASED THE RISK FOR SUBSEQUENT INCIDENT CASES OF PAIN CAUSED BY YOGA. CONCLUSIONS: YOGA CAN CAUSE MUSCULOSKELETAL PAIN. PARTICIPANTS MAY BENEFIT FROM DISCLOSURE OF PRACTICE TO THEIR HEALTHCARE PROFESSIONALS AND BY INFORMING TEACHERS OF INJURIES THEY MAY HAVE PRIOR TO PARTICIPATION. YOGA TEACHERS SHOULD ALSO DISCUSS THE RISKS FOR INJURY WITH THEIR STUDENTS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
12  687  44 EFFECT OF AN OFFICE WORKSITE-BASED YOGA PROGRAM ON HEART RATE VARIABILITY: OUTCOMES OF A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: CHRONIC WORK-RELATED STRESS IS AN INDEPENDENT RISK FACTOR FOR CARDIOMETABOLIC DISEASES AND ASSOCIATED MORTALITY, PARTICULARLY WHEN COMPOUNDED BY A SEDENTARY WORK ENVIRONMENT. THE PURPOSE OF THIS STUDY WAS TO DETERMINE IF AN OFFICE WORKSITE-BASED HATHA YOGA PROGRAM COULD IMPROVE PHYSIOLOGICAL STRESS, EVALUATED VIA HEART RATE VARIABILITY (HRV), AND ASSOCIATED HEALTH-RELATED OUTCOMES IN A COHORT OF OFFICE WORKERS. METHODS: THIRTY-SEVEN ADULTS EMPLOYED IN UNIVERSITY-BASED OFFICE POSITIONS WERE RANDOMIZED UPON THE COMPLETION OF BASELINE TESTING TO AN EXPERIMENTAL OR CONTROL GROUP. THE EXPERIMENTAL GROUP COMPLETED A 10-WEEK YOGA PROGRAM PRESCRIBED THREE SESSIONS PER WEEK DURING LUNCH HOUR (50 MIN PER SESSION). AN EXPERIENCED INSTRUCTOR LED THE SESSIONS, WHICH EMPHASIZED ASANAS (POSTURES) AND VINYASA (EXERCISES). THE PRIMARY OUTCOME WAS THE HIGH FREQUENCY (HF) POWER COMPONENT OF HRV. SECONDARY OUTCOMES INCLUDED ADDITIONAL HRV PARAMETERS, MUSCULOSKELETAL FITNESS (I.E. PUSH-UP, SIDE-BRIDGE, AND SIT & REACH TESTS) AND PSYCHOLOGICAL INDICES (I.E. STATE AND TRAIT ANXIETY, QUALITY OF LIFE AND JOB SATISFACTION). RESULTS: ALL MEASURES OF HRV FAILED TO CHANGE IN THE EXPERIMENTAL GROUP VERSUS THE CONTROL GROUP, EXCEPT THAT THE EXPERIMENTAL GROUP SIGNIFICANTLY INCREASED LF:HF (P = 0.04) AND REDUCED PNN50 (P = 0.04) VERSUS CONTROL, CONTRARY TO OUR HYPOTHESES. FLEXIBILITY, EVALUATED VIA SIT & REACH TEST INCREASED IN THE EXPERIMENTAL GROUP VERSUS THE CONTROL GROUP (P < 0.001). NO OTHER ADAPTATIONS WERE NOTED. POST HOC ANALYSIS COMPARING PARTICIPANTS WHO COMPLETED >/=70% OF YOGA SESSIONS (N = 11) TO CONTROL (N = 19) YIELDED THE SAME FINDINGS, EXCEPT THAT THE HIGH ADHERERS ALSO REDUCED STATE ANXIETY (P = 0.02) AND RMSSD (P = 0.05), AND TENDED TO IMPROVE THE PUSH-UP TEST (P = 0.07) VERSUS CONTROL. CONCLUSIONS: A 10-WEEK HATHA YOGA INTERVENTION DELIVERED AT THE OFFICE WORKSITE DURING LUNCH HOUR DID NOT IMPROVE HF POWER OR OTHER HRV PARAMETERS. HOWEVER, IMPROVEMENTS IN FLEXIBILITY, STATE ANXIETY AND MUSCULOSKELETAL FITNESS WERE NOTED WITH HIGH ADHERENCE. FUTURE INVESTIGATIONS SHOULD INCORPORATE STRATEGIES TO PROMOTE ADHERENCE, INVOLVE MORE FREQUENT AND LONGER DURATIONS OF YOGA TRAINING, AND ENROL COHORTS WHO SUFFER FROM HIGHER LEVELS OF WORK-RELATED STRESS. TRIAL REGISTRATION: ACTRN12611000536965.	2013	
                                                                                                             
13 2858  22 YOGA-BASED CARDIAC REHABILITATION: CURRENT PERSPECTIVES FROM RANDOMIZED CONTROLLED TRIALS IN CORONARY ARTERY DISEASE. CORONARY ARTERY DISEASE CARRIES A HIGH MORBIDITY AND MORTALITY WORLDWIDE, AND EXERCISE-BASED CARDIAC REHABILITATION PROGRAMMES PLAY A LARGE ROLE IN SECONDARY PREVENTION. EXERCISE-BASED REHABILITATION PROGRAMMES ARE EXPENSIVE, AND IN CERTAIN SUBGROUPS UPTAKE IS POOR. YOGA HAS BEEN SUGGESTED TO SHOW IMPROVEMENTS IN CARDIOVASCULAR HEALTH WHICH WOULD SUPPORT ITS USE IN CARDIAC REHABILITATION PROGRAMMES. WE CARRIED OUT A REVIEW OF CURRENT RANDOMIZED CONTROLLED TRIALS TO DETERMINE IF YOGA-BASED CARDIAC REHABILITATION LEADS TO REDUCED CARDIAC RISK FACTORS, AND IMPROVED PHYSIOLOGICAL AND PSYCHOLOGICAL OUTCOMES IN PATIENTS WITH CORONARY ARTERY DISEASE COMPARED TO STANDARD CARE. SIX RANDOMIZED CONTROLLED STUDIES WERE IDENTIFIED AFTER A MEDICAL DATABASE SEARCH, AND META-ANALYSIS WAS CARRIED OUT FOR THE DIFFERENT OUTCOMES. OVERALL, THE ADDITION OF YOGA TO STANDARD CARE RESULTED IN IMPROVED SUBJECTIVE FEELING OF CARDIAC HEALTH AND QUALITY OF LIFE. THERE WAS ALSO A TREND TOWARDS IMPROVEMENT IN LEFT VENTRICULAR SYSTOLIC FUNCTION. IMPROVEMENT IN CARDIAC RISK FACTORS, MACE AND PSYCHOLOGICAL HEALTH IN THIS COHORT HAS STILL TO BE PROVEN, BUT WAS NOT INFERIOR TO STANDARD OR ENHANCED CARE, AND THE BENEFITS BECAME MORE PRONOUNCED AT LONGER FOLLOW-UP. FUTURE STUDIES WITH LONGER FOLLOW-UP AND LARGER PATIENT NUMBERS WOULD AID IN ACCURATELY ASSESSING THE LONG-TERM BENEFIT OF YOGA-BASED REHABILITATION.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
14  668  42 EFFECT OF A 16-WEEK BIKRAM YOGA PROGRAM ON HEART RATE VARIABILITY AND ASSOCIATED CARDIOVASCULAR DISEASE RISK FACTORS IN STRESSED AND SEDENTARY ADULTS: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: CHRONIC ACTIVATION OF THE STRESS-RESPONSE CAN CONTRIBUTE TO CARDIOVASCULAR DISEASE RISK, PARTICULARLY IN SEDENTARY INDIVIDUALS. THIS STUDY INVESTIGATED THE EFFECT OF A BIKRAM YOGA INTERVENTION ON THE HIGH FREQUENCY POWER COMPONENT OF HEART RATE VARIABILITY (HRV) AND ASSOCIATED CARDIOVASCULAR DISEASE (CVD) RISK FACTORS (I.E. ADDITIONAL DOMAINS OF HRV, HEMODYNAMIC, HEMATOLOGIC, ANTHROPOMETRIC AND BODY COMPOSITION OUTCOME MEASURES) IN STRESSED AND SEDENTARY ADULTS. METHODS: ELIGIBLE ADULTS WERE RANDOMIZED TO AN EXPERIMENTAL GROUP (N = 29) OR A NO TREATMENT CONTROL GROUP (N = 34). EXPERIMENTAL GROUP PARTICIPANTS WERE INSTRUCTED TO ATTEND THREE TO FIVE SUPERVISED BIKRAM YOGA CLASSES PER WEEK FOR 16 WEEKS AT LOCAL STUDIOS. OUTCOME MEASURES WERE ASSESSED AT BASELINE (WEEK 0) AND COMPLETION (WEEK 17). RESULTS: SIXTY-THREE ADULTS (37.2 +/- 10.8 YEARS, 79% WOMEN) WERE INCLUDED IN THE INTENTION-TO-TREAT ANALYSIS. THE EXPERIMENTAL GROUP ATTENDED 27 +/- 18 CLASSES. ANALYSES OF COVARIANCE REVEALED NO SIGNIFICANT CHANGE IN THE HIGH-FREQUENCY COMPONENT OF HRV (P = 0.912, PARTIAL ETA (2) = 0.000) OR IN ANY SECONDARY OUTCOME MEASURE BETWEEN GROUPS OVER TIME. HOWEVER, REGRESSION ANALYSES REVEALED THAT HIGHER ATTENDANCE IN THE EXPERIMENTAL GROUP WAS ASSOCIATED WITH SIGNIFICANT REDUCTIONS IN DIASTOLIC BLOOD PRESSURE (P = 0.039; PARTIAL ETA (2) = 0.154), BODY FAT PERCENTAGE (P = 0.001, PARTIAL ETA (2) = 0.379), FAT MASS (P = 0.003, PARTIAL ETA (2) = 0.294) AND BODY MASS INDEX (P = 0.05, PARTIAL ETA (2) = 0.139). CONCLUSIONS: A 16-WEEK BIKRAM YOGA PROGRAM DID NOT INCREASE THE HIGH FREQUENCY POWER COMPONENT OF HRV OR ANY OTHER CVD RISK FACTORS INVESTIGATED. AS REVEALED BY POST HOC ANALYSES, LOW ADHERENCE LIKELY CONTRIBUTED TO THE NULL EFFECTS. FUTURE STUDIES ARE REQUIRED TO ADDRESS BARRIERS TO ADHERENCE TO BETTER ELUCIDATE THE DOSE-RESPONSE EFFECTS OF BIKRAM YOGA PRACTICE AS A MEDIUM TO LOWER STRESS-RELATED CVD RISK. TRIAL REGISTRATION: RETROSPECTIVELY REGISTERED WITH AUSTRALIA NEW ZEALAND CLINICAL TRIALS REGISTRY ACTRN12616000867493 . REGISTERED 04 JULY 2016.	2017	
                                                                                                                                                                                                                                                                                             
15  944  38 EFFECTS OF A 12-WEEK HATHA YOGA INTERVENTION ON METABOLIC RISK AND QUALITY OF LIFE IN HONG KONG CHINESE ADULTS WITH AND WITHOUT METABOLIC SYNDROME. OBJECTIVE: TO DETERMINE THE EFFICACY OF A 12-WEEK HATHA YOGA INTERVENTION TO IMPROVE METABOLIC RISK PROFILES AND HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN CHINESE ADULTS WITH AND WITHOUT METABOLIC SYNDROME (METS). METHODS: WE CONDUCTED A CONTROLLED TRIAL WITHIN AN UNIVERSITY-AFFILIATED HOSPITAL. 173 CHINESE MEN AND WOMEN AGED 18 OR ABOVE WERE ASSIGNED TO EITHER THE YOGA INTERVENTION GROUP (N = 87) OR THE CONTROL GROUP (N = 86). PRIMARY OUTCOMES INCLUDED 12-WEEK CHANGE IN METABOLIC RISK FACTORS AND METS Z SCORE. SECONDARY OUTCOME WAS HRQOL (MEDICAL OUTCOMES SHORT FORM SURVEY AT 12 WEEKS). RESULTS: THE MEAN AGE OF PARTICIPANTS WAS 52.0 (SD 7.4, RANGE 31-71) YEARS. ANALYSIS INVOLVING THE ENTIRE STUDY POPULATION REVEALED THAT THE YOGA GROUP ACHIEVED GREATER DECLINE IN WAIST CIRCUMFERENCE (P<0.001), FASTING GLUCOSE (P<0.01), TRIGLYCERIDES (P<0.05), AND METS Z SCORE (P<0.01). YOGA TRAINING ALSO IMPROVED GENERAL HEALTH PERCEPTIONS (P<0.01), PHYSICAL COMPONENT SCORE (P<0.01), AND SOCIAL FUNCTIONING (P<0.01) DOMAINS SCORE OF HRQOL. HOWEVER, NO SIGNIFICANT DIFFERENCES BETWEEN GROUPS WERE OBSERVED IN THE MEAN CHANGE OF SYSTOLIC/DIASTOLIC BLOOD PRESSURES OR HIGH-DENSITY LIPID PROTEIN CHOLESTEROL (ALL P>0.05). THERE WERE NO SIGNIFICANT DIFFERENCES IN THE INTERVENTION EFFECTS ON WAIST CIRCUMFERENCE AND METS Z SCORE BETWEEN THE METS SUBGROUPS (BOTH P>0.05). CONCLUSION: A 12-WEEK HATHA YOGA INTERVENTION IMPROVES METABOLIC RISK PROFILES AND HRQOL IN CHINESE ADULTS WITH AND WITHOUT METS. TRIAL REGISTRATION: AUSTRALIAN NEW ZEALAND CLINICAL TRIALS REGISTRY ACTRN12613000816752.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
16 1445  30 INCREASING TREND OF YOGA PRACTICE AMONG U.S. ADULTS FROM 2002 TO 2017. INTRODUCTION: BENEFITS, RISKS, AND THE INCREASING POPULARITY OF YOGA USE WARRANT ASSESSING YOGA PRACTICE PREVALENCE AND USERS' PROFILES. THIS STUDY DESCRIBES TRENDS IN YOGA PRACTICE EXCLUSIVELY AMONG AMERICAN ADULTS FROM 2002 TO 2017, COMPARES THE PROFILE OF YOGA USERS, AND IDENTIFIES FACTORS RELATED TO YOGA USE OVER TIME. MATERIALS AND METHODS: THIS STUDY IS A SECONDARY ANALYSIS DONE IN 2019 AND 2020 USING THE NATIONAL HEALTH INTERVIEW SURVEY (NHIS) 2002, 2007, 2012, AND 2017 DATA. POPULATION WEIGHTS WERE USED TO OBTAIN STATISTICALLY ACCURATE ESTIMATES OF YOGA USE PREVALENCE FOR THE U.S. POPULATION. DESCRIPTIVE STATISTICS WERE USED TO PROFILE THE SOCIODEMOGRAPHIC AND HEALTH-RELATED CHARACTERISTICS OF YOGA USERS. MULTIVARIABLE LOGISTIC REGRESSION WAS USED TO IDENTIFY FACTORS ASSOCIATED WITH YOGA USE IN EACH COHORT DEFINED BY THE NHIS YEAR. RESULTS: YOGA PRACTICE PREVALENCE NEARLY TRIPLED FROM 5.1% IN 2002 TO 13.7% IN 2017 (WEIGHTED ESTIMATE 10,386,456 AND 32,761,194 AMERICAN ADULTS, RESPECTIVELY). TYPICAL YOGA USERS WERE YOUNG NON-HISPANIC SINGLE WHITE FEMALE ADULTS WITH BACHELOR OR HIGHER EDUCATION AND HEALTH INSURANCE, AND RESIDED IN THE WEST REGION OF THE UNITED STATES. YOGA USE PATTERN CHANGE OVER TIME WAS SIGNIFICANTLY RELATED TO ONLY YOUNGER AGE (P < 0.001) BUT NOT TO OTHER SOCIODEMOGRAPHIC OR HEALTH-RELATED FACTORS. CONCLUSIONS: YOGA HAS GAINED INCREASING POPULARITY IN THE PAST TWO DECADES AMONG AMERICAN ADULTS, WITH YOUNGER ADULTS BEING THE DRIVING FORCE. YOGA APPEARS TO BE ADOPTED FOR GENERAL WELL-BEING OR PREVENTION MORE THAN FOR SPECIFIC DISEASE TREATMENT. FUTURE RESEARCH SHOULD EVALUATE HOW YOGA CAN BE EFFECTIVELY AND SAFELY INTEGRATED INTO PREVENTIVE MEDICINE STRATEGIES.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
17  660  39 EFFECT OF 12 WEEKS OF YOGA THERAPY ON QUALITY OF LIFE AND INDIAN DIABETES RISK SCORE IN NORMOTENSIVE INDIAN YOUNG ADULT PREDIABETICS AND DIABETICS: RANDOMIZED CONTROL TRIAL. INTRODUCTION: INDIA HAS BECOME THE EPICENTRE FOR DIABETES, A STRESS-RELATED DISORDER AFFECTING THE WORKING SKILLS AND DAY-TO-DAY LIFESTYLE MANAGEMENT OF YOUNGER POPULATION. MOST OF THE STUDIES HAVE REPORTED THE EFFECT OF YOGA ON IMPROVING QUALITY OF LIFE (QOL) IN DIABETIC PATIENTS WITH OTHER COMORBIDITIES. TILL DATE, NO RANDOMIZED CONTROL TRIAL REPORTS ARE AVAILABLE TO SHOW THE EFFECT OF YOGA THERAPY ON QOL AND INDIAN DIABETES RISK SCORE (IDRS) IN NORMOTENSIVE PREDIABETIC AND DIABETIC YOUNG INDIVIDUALS. AIM: TO DETERMINE THE EFFECT OF 12 WEEKS OF YOGA THERAPY ON QOL AND IDRS AMONG NORMOTENSIVE PREDIABETIC AND DIABETIC YOUNG INDIAN ADULTS. MATERIALS AND METHODS: A RANDOMIZED CONTROL TRIAL WAS CONDUCTED IN ENDOCRINOLOGY OUTPATIENT DEPARTMENT (OPD). NORMOTENSIVE PARTICIPANTS (N=310) AGED 18-45 YEARS WERE DIVIDED INTO HEALTHY CONTROLS (N=62), PREDIABETICS (N=124) AND DIABETICS (N=124). STUDY GROUP SUBJECTS WERE RANDOMLY ASSIGNED TO GROUP II (N=62, PREDIABETES-STANDARD TREATMENT), GROUP III (N=62, PREDIABETES-STANDARD TREATMENT + YOGA THERAPY), GROUP IV (N=62, DIABETES-STANDARD TREATMENT) AND GROUP V (N=62, DIABETES-STANDARD TREATMENT + YOGA THERAPY). FLANAGAN QOL SCALE, IDRS QUESTIONNAIRE, FASTING PLASMA GLUCOSE (FPG) AND INSULIN WERE ASSESSED PRE AND POST 12 WEEKS OF INTERVENTION. STATISTICAL ANALYSIS WAS DONE USING STUDENT'S PAIRED T-TEST AND ONE-WAY ANOVA. RESULTS: PRE-POST INTERVENTION ANALYSIS SHOWED SIGNIFICANT IMPROVEMENT IN QOL SCALE WITH P<0.01 IN GROUP II AND GROUP IV; P<0.001 IN GROUP III AND GROUP V RESPECTIVELY. THERE WAS SIGNIFICANT REDUCTION IN IDRS IN GROUP II (P<0.05); P<0.001 IN GROUP III, GROUP IV AND GROUP V RESPECTIVELY. SIGNIFICANT DIFFERENCE (P<0.001) IN QOL SCALE AND IDRS WERE FOUND WHEN STUDY GROUPS WITH STANDARD TREATMENT ALONG WITH YOGA THERAPY WERE COMPARED TO STANDARD TREATMENT ALONE. CONCLUSION: YOGA THERAPY ALONG WITH STANDARD TREATMENT FOR 12 WEEKS IMPROVED QOL AND ATTENUATED THE DIABETES RISK AMONG INDIAN PREDIABETICS AND DIABETICS COMPARED TO STANDARD TREATMENT ALONE.	2017	
                                                                                                                                                                                                                                                                                                                                                         
18  906  26 EFFECTIVENESS OF APP-BASED YOGA OF IMMORTALS (YOI) INTERVENTION FOR INSOMNIA IN ASIAN POPULATION DURING PANDEMIC RESTRICTIONS. THE CORONAVIRUS DISEASE 2019 (COVID-19) PANDEMIC CREATED SIGNIFICANT PSYCHOLOGICAL CHALLENGES WORLDWIDE, INCLUDING STRESS, EMOTIONAL DISTRESS, AND INSOMNIA. IN ADDITION, SOCIAL DISTANCING, TRAVEL RESTRICTIONS, AND SPREAD OF DISEASE HAVE RESULTED IN UNIQUE CHALLENGES, CREATING BARRIERS TO HEALTHCARE ACCESS. COMPARED TO THE RATE PRIOR TO THE COVID-19 PANDEMIC, A SIGNIFICANT INCREASE IN CLINICAL INSOMNIA RATES HAVE BEEN REPORTED. WITH WELL-KNOWN LIMITATIONS OF CURRENTLY ESTABLISHED TREATMENTS (E.G., COGNITIVE BEHAVIORAL THERAPY-INSOMNIA (CBT-I), PHARMACOTHERAPY), THERE IS A NEED TO EXPLORE OTHER EFFECTIVE AND SAFE TREATMENT MODALITIES TO TREAT INSOMNIA, ESPECIALLY THOSE THAT CAN BE USED REMOTELY. THE PURPOSE OF THIS STUDY IS TO ASSESS THE EFFECTIVENESS OF APP-BASED INTERVENTION TO TREAT INSOMNIA IN THE CURRENT ERA OF THE COVID-19 PANDEMIC (USING THE YOGA OF IMMORTALS (YOI) APP). THIS PROSPECTIVE COHORT STUDY WAS APPROVED BY THE INSTITUTIONAL REVIEW BOARD. ALL PARTICIPANTS IN THIS STUDY WERE ASKED TO COMPLETE AN ONLINE SURVEY INCLUDING DEMOGRAPHIC DATA AND VALIDATED INSOMNIA SEVERITY INDEX (ISI) AT BASELINE (15 MAY 2020), 4 WEEKS, AND 8 WEEKS AFTER STARTING THE YOI INTERVENTION. SURVEY DATA WAS EXPORTED USING MICROSOFT EXCEL. STATISTICAL ANALYSIS WAS DONE USING THE GRAPHPAD PRISM 8. YOI INTERVENTION SIGNIFICANTLY IMPROVED THE MEAN ISI SCORES IN ALL CATEGORIES OF INSOMNIA (SEVERE, MODERATE, AND SUBTHRESHOLD) AT EACH FOLLOW-UP (P </= 0.0001). THE IMPROVEMENT WAS SIGNIFICANT AMONG ALL AGE GROUPS AND IN BOTH GENDERS. IN OUR STUDY, YOI WAS A NOVEL AND EFFECTIVE INTERVENTION FOR IMPROVING INSOMNIA SYMPTOMS AND MAY BE A NEW ADDITION TO THE ARMAMENTARIUM OF INSOMNIA MANAGEMENT. BEING APP-BASED, THIS HAS POTENTIAL WIDER APPLICABILITY, ESPECIALLY DURING THE CURRENT COVID-19 PANDEMIC.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
19  938  39 EFFECTS OF 1-YEAR YOGA ON CARDIOVASCULAR RISK FACTORS IN MIDDLE-AGED AND OLDER ADULTS WITH METABOLIC SYNDROME: A RANDOMIZED TRIAL. BACKGROUND: METABOLIC SYNDROME (METS) IS A CLUSTERING OF CARDIOVASCULAR RISK FACTORS, WHICH IS ASSOCIATED WITH DIABETES MELLITUS AND CARDIOVASCULAR DISEASE. LIFESTYLE INTERVENTIONS APPLIED TO PEOPLE WITH METS HAS CONSIDERABLE BENEFICIAL EFFECTS ON DISEASE PREVENTIVE OUTCOMES. THIS STUDY AIMED TO EXAMINE THE EFFECTS OF 1-YEAR OF YOGA EXERCISE ON THE CARDIOVASCULAR RISK FACTORS INCLUDING CENTRAL OBESITY, HYPERTENSION, DYSLIPIDEMIA AND HYPERGLYCEMIA IN MIDDLE-AGED AND OLDER HONG KONG CHINESE ADULTS WITH METS. METHODS: ADULTS DIAGNOSED WITH METS USING NATIONAL CHOLESTEROL EDUCATION PROGRAM CRITERIA (N = 182; MEAN +/- SD AGE = 56 +/- 9.1) WERE RANDOMLY ASSIGNED TO A 1-YEAR YOGA INTERVENTION GROUP OR CONTROL GROUP. SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, WAIST CIRCUMFERENCE, FASTING PLASMA GLUCOSE, TRIGLYCERIDES, AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL WERE EXAMINED AT BASELINE, MIDWAY, AND ON COMPLETION OF THE STUDY. PHYSICAL ACTIVITY LEVEL AND CALORIC INTAKE WERE ASSESSED AND INCLUDED IN THE COVARIATE ANALYSES. RESULTS: A REDUCTION OF THE NUMBER OF DIAGNOSTIC COMPONENTS FOR METS WAS FOUND TO BE ASSOCIATED WITH THE YOGA INTERVENTION. WAIST CIRCUMFERENCE WAS SIGNIFICANTLY IMPROVED AFTER THE 1-YEAR YOGA INTERVENTION. A TREND TOWARDS A DECREASE IN SYSTOLIC BLOOD PRESSURE WAS OBSERVED FOLLOWING YOGA INTERVENTION. CONCLUSION: THESE RESULTS SUGGEST THAT YOGA EXERCISE IMPROVES THE CARDIOVASCULAR RISK FACTORS INCLUDING CENTRAL OBESITY AND BLOOD PRESSURE IN MIDDLE-AGED AND OLDER ADULTS WITH METS. THESE FINDINGS SUPPORT THE COMPLEMENTARY BENEFICIAL ROLE OF YOGA IN MANAGING METS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
20  674  30 EFFECT OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE IN OVERWEIGHT AND OBESE SUBJECTS. OBJECTIVE: TO STUDY THE EFFECT OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN OVERWEIGHT AND OBESE PERSONS. DESIGN AND SETTING: NONRANDOMIZED, SINGLE-ARM INTERVENTIONAL STUDY CONDUCTED FROM AUGUST 2012 TO MARCH 2015 AT INTEGRAL HEALTH CLINIC, DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA. PARTICIPANTS: OVERWEIGHT (BODY-MASS INDEX [BMI], 23-24.9 KG/M(2)) AND OBESE (BMI, >/=25 KG/M(2)) PERSONS (N = 279) AGED 20-60 YEARS. INTERVENTION: PRETESTED YOGA-BASED LIFESTYLE INTERVENTION, INCLUDING ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), RELAXATION TECHNIQUES, LECTURES, GROUP SUPPORT, NUTRITION AWARENESS PROGRAM, AND INDIVIDUALIZED ADVICE. OUTCOME MEASURES: PRIMARY OUTCOME MEASURE WAS HRQOL, MEASURED BY USING SHORT VERSION OF WORLD HEALTH ORGANIZATION QUALITY OF LIFE (WHOQOL-BREF) QUESTIONNAIRE. SECONDARY OUTCOME MEASURES WERE ANTHROPOMETRIC VARIABLES, SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, PULSE RATE, LIPID PROFILE, AND FASTING GLUCOSE. A SUBGROUP ANALYSIS ACCORDING TO SEX WAS ALSO PERFORMED. RESULTS: THE OVERALL QUALITY OF LIFE AND HEALTH IMPROVED AFTER SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION IN OVERWEIGHT AND OBESE PERSONS. PHYSICAL, PSYCHOLOGICAL AND ENVIRONMENTAL DOMAIN SCORES SIGNIFICANTLY INCREASED FROM BASELINE TO DAY 10, AND EFFICACY WAS NOTED IN BOTH MALE AND FEMALE SUBGROUPS. AFTER 10 DAYS OF INTERVENTION, THE FOLLOWING ALSO DECREASED SIGNIFICANTLY: BODY WEIGHT, BMI, TOTAL BODY FAT, WAIST AND HIP CIRCUMFERENCE, WAIST-TO-HIP RATIO, SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, TOTAL CHOLESTEROL, LOW-DENSITY LIPOPROTEIN, TRIGLYCERIDES, AND FASTING GLUCOSE. CONCLUSION: A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION HAD A POSITIVE EFFECT ON HRQOL IN OVERWEIGHT AND OBESE PERSONS.	2016