1 2277 69 THE ROLES OF EXERCISE AND YOGA IN AMELIORATING DEPRESSION AS A RISK FACTOR FOR COGNITIVE DECLINE. CURRENTLY, THERE ARE NO EFFECTIVE PHARMACEUTICAL TREATMENTS TO REDUCE COGNITIVE DECLINE OR PREVENT DEMENTIA. AT THE SAME TIME, THE GLOBAL POPULATION IS AGING, AND RATES OF DEMENTIA AND MILD COGNITIVE IMPAIRMENT (MCI) ARE ON THE RISE. AS SUCH, THERE IS AN INCREASING INTEREST IN COMPLEMENTARY AND ALTERNATIVE INTERVENTIONS TO TREAT OR REDUCE THE RISK OF COGNITIVE DECLINE. DEPRESSION IS ONE POTENTIALLY MODIFIABLE RISK FACTOR FOR COGNITIVE DECLINE AND DEMENTIA. NOTABLY, EXERCISE AND YOGA ARE TWO INTERVENTIONS KNOWN TO BOTH REDUCE SYMPTOMS OF DEPRESSION AND IMPROVE COGNITIVE FUNCTION. THE CURRENT REVIEW DISCUSSES THE EFFICACY OF EXERCISE AND YOGA TO AMELIORATE DEPRESSION AND THEREBY REDUCE THE RISK OF COGNITIVE DECLINE AND POTENTIALLY PREVENT DEMENTIA. POTENTIAL MECHANISMS OF CHANGE, TREATMENT IMPLICATIONS, AND FUTURE DIRECTIONS ARE DISCUSSED.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
2 2179 27 THE EFFECTS OF YOGA ON PATIENTS WITH MILD COGNITIVE IMPAIRMENT AND DEMENTIA: A SCOPING REVIEW. YOGA IS AN ANCIENT MIND BODY PRACTICE. ALTHOUGH YOGA HAS BEEN USED AS A COMPLEMENTARY HEALTH APPROACH FOR ENHANCING WELLNESS AND ADDRESSING A VARIETY OF HEALTH ISSUES, LITTLE IS KNOWN ABOUT THE IMPACT OF YOGA ON COGNITIVE FUNCTIONING IN ADULTS WITH MILD COGNITIVE IMPAIRMENT (MCI) AND DEMENTIA. WE CONDUCTED A LITERATURE REVIEW TO EXAMINE THE IMPACT OF YOGA ON PERSONS WITH MCI AND DEMENTIA. EIGHT STUDIES WERE IDENTIFIED THAT REPORTED ON YOGA AS EITHER THE PRIMARY INTERVENTION OR ONE COMPONENT OF A MULTI-COMPONENT INTERVENTION IN SAMPLES OF PERSONS WITH MCI OR DEMENTIA. RESULTS SUGGEST THAT YOGA MAY HAVE BENEFICIAL EFFECTS ON COGNITIVE FUNCTIONING, PARTICULARLY ON ATTENTION AND VERBAL MEMORY. FURTHER, YOGA MAY AFFECT COGNITIVE FUNCTIONING THROUGH IMPROVED SLEEP, MOOD, AND NEURAL CONNECTIVITY. THERE ARE A NUMBER OF LIMITATIONS OF THE EXISTING STUDIES, INCLUDING A LACK OF INTERVENTION DETAILS, AS WELL AS VARIABILITY IN THE FREQUENCY/DURATION AND COMPONENTS OF THE YOGA INTERVENTIONS. A FURTHER COMPLICATING ISSUE IS THE ROLE OF VARIOUS UNDERLYING ETIOLOGIES OF COGNITIVE IMPAIRMENT. DESPITE THESE LIMITATIONS, PROVIDERS MAY CONSIDER RECOMMENDING YOGA TO PERSONS WITH MCI OR DEMENTIA AS A SAFE AND POTENTIALLY BENEFICIAL COMPLEMENTARY HEALTH APPROACH.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
3  455 24 CHANGES IN NEURAL CONNECTIVITY AND MEMORY FOLLOWING A YOGA INTERVENTION FOR OLDER ADULTS: A PILOT STUDY. BACKGROUND: NO STUDY HAS EXPLORED THE EFFECT OF YOGA ON COGNITIVE DECLINE AND RESTING-STATE FUNCTIONAL CONNECTIVITY. OBJECTIVES: THIS STUDY EXPLORED THE RELATIONSHIP BETWEEN PERFORMANCE ON MEMORY TESTS AND RESTING-STATE FUNCTIONAL CONNECTIVITY BEFORE AND AFTER A YOGA INTERVENTION VERSUS ACTIVE CONTROL FOR SUBJECTS WITH MILD COGNITIVE IMPAIRMENT (MCI). METHODS: PARTICIPANTS ( >/= 55 Y) WITH MCI WERE RANDOMIZED TO RECEIVE A YOGA INTERVENTION OR ACTIVE "GOLD-STANDARD" CONTROL (I.E., MEMORY ENHANCEMENT TRAINING (MET)) FOR 12 WEEKS. RESTING-STATE FUNCTIONAL MAGNETIC RESONANCE IMAGING WAS USED TO MAP CORRELATIONS BETWEEN BRAIN NETWORKS AND MEMORY PERFORMANCE CHANGES OVER TIME. DEFAULT MODE NETWORKS (DMN), LANGUAGE AND SUPERIOR PARIETAL NETWORKS WERE CHOSEN AS NETWORKS OF INTEREST TO ANALYZE THE ASSOCIATION WITH CHANGES IN VERBAL AND VISUOSPATIAL MEMORY PERFORMANCE. RESULTS: FOURTEEN YOGA AND 11 MET PARTICIPANTS COMPLETED THE STUDY. THE YOGA GROUP DEMONSTRATED A STATISTICALLY SIGNIFICANT IMPROVEMENT IN DEPRESSION AND VISUOSPATIAL MEMORY. WE OBSERVED IMPROVED VERBAL MEMORY PERFORMANCE CORRELATED WITH INCREASED CONNECTIVITY BETWEEN THE DMN AND FRONTAL MEDIAL CORTEX, PREGENUAL ANTERIOR CINGULATE CORTEX, RIGHT MIDDLE FRONTAL CORTEX, POSTERIOR CINGULATE CORTEX, AND LEFT LATERAL OCCIPITAL CORTEX. IMPROVED VERBAL MEMORY PERFORMANCE POSITIVELY CORRELATED WITH INCREASED CONNECTIVITY BETWEEN THE LANGUAGE PROCESSING NETWORK AND THE LEFT INFERIOR FRONTAL GYRUS. IMPROVED VISUOSPATIAL MEMORY PERFORMANCE CORRELATED INVERSELY WITH CONNECTIVITY BETWEEN THE SUPERIOR PARIETAL NETWORK AND THE MEDIAL PARIETAL CORTEX. CONCLUSION: YOGA MAY BE AS EFFECTIVE AS MET IN IMPROVING FUNCTIONAL CONNECTIVITY IN RELATION TO VERBAL MEMORY PERFORMANCE. THESE FINDINGS SHOULD BE CONFIRMED IN LARGER PROSPECTIVE STUDIES.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
4  176 34 A RANDOMIZED CONTROLLED TRIAL OF KUNDALINI YOGA IN MILD COGNITIVE IMPAIRMENT. BACKGROUND: GLOBAL POPULATION AGING WILL RESULT IN INCREASING RATES OF COGNITIVE DECLINE AND DEMENTIA. THUS, EFFECTIVE, LOW-COST, AND LOW SIDE-EFFECT INTERVENTIONS FOR THE TREATMENT AND PREVENTION OF COGNITIVE DECLINE ARE URGENTLY NEEDED. OUR STUDY IS THE FIRST TO INVESTIGATE THE EFFECTS OF KUNDALINI YOGA (KY) TRAINING ON MILD COGNITIVE IMPAIRMENT (MCI). METHODS: OLDER PARTICIPANTS (>/=55 YEARS OF AGE) WITH MCI WERE RANDOMIZED TO EITHER A 12-WEEK KY INTERVENTION OR MEMORY ENHANCEMENT TRAINING (MET; GOLD-STANDARD, ACTIVE CONTROL). COGNITIVE (I.E. MEMORY AND EXECUTIVE FUNCTIONING) AND MOOD (I.E. DEPRESSION, APATHY, AND RESILIENCE) ASSESSMENTS WERE ADMINISTERED AT BASELINE, 12 WEEKS AND 24 WEEKS. RESULTS: AT BASELINE, 81 PARTICIPANTS HAD NO SIGNIFICANT BASELINE GROUP DIFFERENCES IN CLINICAL OR DEMOGRAPHIC CHARACTERISTICS. AT 12 WEEKS AND 24 WEEKS, BOTH KY AND MET GROUPS SHOWED SIGNIFICANT IMPROVEMENT IN MEMORY; HOWEVER, ONLY KY SHOWED SIGNIFICANT IMPROVEMENT IN EXECUTIVE FUNCTIONING. ONLY THE KY GROUP SHOWED SIGNIFICANT IMPROVEMENT IN DEPRESSIVE SYMPTOMS AND RESILIENCE AT WEEK 12. CONCLUSION: KY GROUP SHOWED SHORT- AND LONG-TERM IMPROVEMENTS IN EXECUTIVE FUNCTIONING AS COMPARED TO MET, AND BROADER EFFECTS ON DEPRESSED MOOD AND RESILIENCE. THIS OBSERVATION SHOULD BE CONFIRMED IN FUTURE CLINICAL TRIALS OF YOGA INTERVENTION FOR TREATMENT AND PREVENTION OF COGNITIVE DECLINE (NCT01983930).	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
5 1304 20 HATHA YOGA PRACTICE IMPROVES ATTENTION AND PROCESSING SPEED IN OLDER ADULTS: RESULTS FROM AN 8-WEEK RANDOMIZED CONTROL TRIAL. BACKGROUND: AGE-RELATED COGNITIVE DECLINE IS WELL DOCUMENTED ACROSS VARIOUS ASPECTS OF COGNITIVE FUNCTION, INCLUDING ATTENTION AND PROCESSING SPEED, AND LIFESTYLE BEHAVIORS SUCH AS PHYSICAL ACTIVITY PLAY AN IMPORTANT ROLE IN PREVENTING COGNITIVE DECLINE AND MAINTAINING OR EVEN IMPROVING COGNITIVE FUNCTION. PURPOSE: THE PURPOSE OF THIS STUDY WAS TO EVALUATE THE EFFECTS OF AN 8-WEEK HATHA YOGA INTERVENTION ON ATTENTION AND PROCESSING SPEED AMONG OLDER ADULTS. METHODS: PARTICIPANTS (N = 118; MEAN AGE, 62 +/- 5.59) WERE RANDOMLY ASSIGNED TO AN 8-WEEK HATHA YOGA GROUP OR A STRETCHING CONTROL GROUP AND COMPLETED COGNITIVE ASSESSMENTS-ATTENTION NETWORK TASK, TRAIL MAKING TEST PARTS A AND B, AND PATTERN COMPARISON TEST-AT BASELINE AND AFTER THE 8-WEEK INTERVENTION. RESULTS: ANALYSES OF COVARIANCE REVEALED SIGNIFICANTLY FASTER REACTION TIMES FOR THE YOGA GROUP ON THE ATTENTION NETWORK TASK'S NEUTRAL, CONGRUENT, AND INCONGRUENT CONDITIONS (P </= 0.04). THE YOGA INTERVENTION ALSO IMPROVED PARTICIPANTS' VISUOSPATIAL AND PERCEPTUAL PROCESSING ON THE TRAIL MAKING TEST PART B (P = 0.002) AND PATTERN COMPARISON (P < 0.001) TESTS. CONCLUSIONS: THESE RESULTS SUGGEST THAT YOGA PRACTICE THAT INCLUDES POSTURES, BREATHING, AND MEDITATIVE EXERCISES LEAD TO IMPROVED ATTENTIONAL AND INFORMATION PROCESSING ABILITIES. ALTHOUGH THE UNDERLYING MECHANISMS REMAIN LARGELY SPECULATIVE, MORE SYSTEMATIC TRIALS ARE NEEDED TO EXPLORE THE EXTENT OF COGNITIVE BENEFITS AND THEIR NEUROBIOLOGICAL MECHANISMS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
6 1626 22 MINDFULNESS TRAINING FOR IMPROVING ATTENTION REGULATION IN UNIVERSITY STUDENTS: IS IT EFFECTIVE? AND DO YOGA AND HOMEWORK MATTER? THE PRESENT STUDY EXAMINED THE EFFECTS OF MINDFULNESS TRAINING ON ATTENTION REGULATION IN UNIVERSITY STUDENTS AND WHETHER THE POTENTIAL BENEFITS OF IMPLEMENTATION ARE INFLUENCED BY THE YOGA COMPONENT OF MINDFULNESS-BASED INTERVENTIONS (MBIS) AND/OR BY MBI HOMEWORK PRACTICE. IN A NON-RANDOMIZED TRIAL WITH PRE- AND POST-ASSESSMENTS, N = 180 UNIVERSITY STUDENTS WERE ALLOCATED TO EITHER MINDFULNESS TRAINING (EXPERIMENTAL GROUPS), AWARENESS ACTIVITIES (ACTIVE CONTROL GROUP), OR NO TRAINING (PASSIVE CONTROL GROUP). MINDFULNESS WAS TAUGHT THROUGH TWO MBIS, ONE INCLUDING YOGA AND THE OTHER EXCLUDING YOGA. ATTENTION REGULATION WAS OPERATIONALIZED VIA BEHAVIORAL INDICATORS, NAMELY SUSTAINED ATTENTION, COGNITIVE FLEXIBILITY, COGNITIVE INHIBITION, AND DATA-DRIVEN INFORMATION PROCESSING. WITH THE EXCEPTION OF SPEED IN A COGNITIVE FLEXIBILITY TASK, THE RESULTS INDICATED NO SYSTEMATIC OR DIFFERENTIAL ADVANTAGE ARISING FROM MINDFULNESS TRAINING, WITH OR WITHOUT YOGA, REGARDING THE ASPECTS OF ATTENTION REGULATION. THERE WAS NO CONSISTENT INFLUENCE OF HOMEWORK QUANTITY OR QUALITY. THE IMPLICATIONS FOR MINDFULNESS TRAINING IN ACADEMIC CONTEXTS ARE DISCUSSED.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
7 2872 21 YOGA-ENHANCED COGNITIVE BEHAVIOURAL THERAPY (Y-CBT) FOR ANXIETY MANAGEMENT: A PILOT STUDY. COGNITIVE BEHAVIOURAL THERAPY (CBT) IS AN EFFECTIVE TREATMENT FOR GENERALIZED ANXIETY DISORDER, BUT THERE IS STILL ROOM FOR IMPROVEMENT. THE AIM OF THE PRESENT STUDY WAS TO EXAMINE THE POTENTIAL BENEFIT OF ENRICHING CBT WITH KUNDALINI YOGA (Y-CBT). PARTICIPANTS CONSISTED OF TREATMENT RESISTANT CLIENTS AT A COMMUNITY MENTAL HEALTH CLINIC. A TOTAL OF 32 PARTICIPANTS ENROLLED IN THE STUDY AND 22 COMPLETED THE PROGRAMME. AFTER THE Y-CBT INTERVENTION, PRE-POST COMPARISONS SHOWED STATISTICALLY SIGNIFICANT IMPROVEMENTS IN STATE AND TRAIT ANXIETY, DEPRESSION, PANIC, SLEEP AND QUALITY OF LIFE. RESULTS FROM THIS PRELIMINARY STUDY SUGGEST THAT Y-CBT MAY HAVE POTENTIAL AS A PROMISING TREATMENT FOR THOSE SUFFERING FROM GENERALIZED ANXIETY DISORDER. KEY PRACTITIONER MESSAGES: YOGA-ENHANCED COGNITIVE BEHAVIOURAL THERAPY (Y-CBT) MAY BE A PROMISING NEW TREATMENT FOR THOSE SUFFERING FROM GENERALIZED ANXIETY DISORDER. Y-CBT MAY ALSO REDUCE DEPRESSION IN THOSE SUFFERING FROM GENERALIZED ANXIETY. Y-CBT MAY REDUCE DEPRESSION AND ANXIETY IN A CLINIC POPULATION WHERE CLIENTS SUFFER FROM MULTIPLE DIAGNOSES INCLUDING GENERALIZED ANXIETY DISORDER.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
8   76 20 A HEURISTIC MODEL LINKING YOGA PHILOSOPHY AND SELF-REFLECTION TO EXAMINE UNDERLYING MECHANISMS OF ADD-ON YOGA TREATMENT IN SCHIZOPHRENIA. PRELIMINARY EVIDENCE SUGGESTS EFFICACY OF YOGA AS ADD-ON TREATMENT FOR SCHIZOPHRENIA, BUT THE UNDERLYING MECHANISM BY WHICH YOGA IMPROVES THE SYMPTOMS OF SCHIZOPHRENIA IS NOT COMPLETELY UNDERSTOOD. YOGA IMPROVES SELF-REFLECTION IN HEALTHY INDIVIDUALS, AND SELF-REFLECTION ABNORMALITIES ARE TYPICALLY SEEN IN SCHIZOPHRENIA. HOWEVER, WHETHER YOGA TREATMENT IMPROVES IMPAIRMENTS IN SELF-REFLECTION TYPICALLY SEEN IN PATIENTS WITH SCHIZOPHRENIA IS NOT EXAMINED. THIS PAPER DISCUSSES THE POTENTIAL MECHANISM OF YOGA IN THE TREATMENT OF SCHIZOPHRENIA AND PROPOSES A TESTABLE HYPOTHESIS FOR FURTHER EMPIRICAL STUDIES. IT IS PROPOSED THAT SELF-REFLECTION ABNORMALITIES IN SCHIZOPHRENIA IMPROVE WITH YOGA AND THE NEUROBIOLOGICAL CHANGES ASSOCIATED WITH THIS CAN BE EXAMINED USING EMPIRICAL BEHAVIOURAL MEASURES AND NEUROIMAGING MEASURES SUCH AS MAGNETIC RESONANCE IMAGING.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
9  644 21 DOES YOGA HAVE A ROLE IN SCHIZOPHRENIA MANAGEMENT? PURPOSE OF REVIEW: TO REVIEW THE EFFICACY OF ADD-ON YOGA THERAPY IN IMPROVING SYMPTOMS OF SCHIZOPHRENIA AND QUALITY OF LIFE AND EXAMINE THE POSSIBLE UNDERLYING BIOLOGICAL MECHANISMS OF YOGA IN SCHIZOPHRENIA. RECENT FINDINGS: QUALITY OF LIFE, COGNITIVE SYMPTOMS, AND NEGATIVE SYMPTOMS HAVE BEEN FOUND TO IMPROVE WITH ADD-ON YOGA THERAPY IN SCHIZOPHRENIA (POOLED MEAN EFFECT SIZE 0.8, 0.6, AND 0.4, RESPECTIVELY). YOGA ALSO SEEMS TO HAVE A SMALL EFFECT ON IMPROVING POSITIVE SYMPTOMS. LESS EXPLORED AREAS INCLUDE ADVERSE EFFECTS OF YOGA ITSELF AS WELL AS ITS EFFECTS ON ANTIPSYCHOTIC-INDUCED COMPLICATIONS. PRELIMINARY FINDINGS SUGGEST THAT THE EFFECTS OF YOGA MAY BE MEDIATED BY NEUROHORMONAL MECHANISMS AND FUNCTIONAL CHANGES IN BRAIN ACTIVITY. ADD-ON YOGA THERAPY IS A POTENTIAL TREATMENT OPTION FOR IMPROVING QUALITY OF LIFE, COGNITIVE SYMPTOMS, AND NEGATIVE SYMPTOMS IN SCHIZOPHRENIA. FUTURE STUDIES SHOULD EXPLORE EFFICACY IN MULTICENTRIC TRIALS AS WELL AS POSSIBLE NEUROBIOLOGICAL CHANGES UNDERLYING THE EFFECTS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
10  133 21 A PRAGMATIC PREFERENCE TRIAL OF THERAPEUTIC YOGA AS AN ADJUNCT TO GROUP COGNITIVE BEHAVIOUR THERAPY VERSUS GROUP CBT ALONE FOR DEPRESSION AND ANXIETY. BACKGROUND: YOGA HAS SEVERAL MECHANISMS THAT MAKE IT A PROMISING TREATMENT FOR DEPRESSION AND ANXIETY, INCLUDING PHYSICAL ACTIVITY, BEHAVIOURAL ACTIVATION, AND MINDFULNESS. FOLLOWING POSITIVE OUTCOMES FROM ADAPTED CBT INTERVENTIONS INCORPORATING MINDFULNESS-BASED PRACTICES, THIS STUDY EXPLORED THE EFFECTS OF A THERAPEUTIC YOGA PROGRAM AS AN ADJUNCT TO GROUP-BASED CBT FOR DEPRESSION OR ANXIETY. METHODS: THIS WAS A PRAGMATIC PREFERENCE TRIAL INVOLVING ADULTS DIAGNOSED WITH DEPRESSION OR ANXIETY IN A REGIONAL PRIMARY MENTAL HEALTHCARE SERVICE (N = 59), COMPARING TRANSDIAGNOSTIC GROUP CBT (N = 27) WITH TRANSDIAGNOSTIC GROUP CBT COMBINED WITH AN ADJUNCT THERAPEUTIC YOGA PROGRAM (N = 32). A PREFERENCE RECRUITMENT DESIGN ALLOWED ELIGIBLE PARTICIPANTS (N = 35) TO SELF-SELECT INTO THE ADJUNCT PROGRAM. THE DEPRESSION ANXIETY STRESS SCALE-21 (DASS) WAS ASSESSED AT BASELINE, POST-INTERVENTION, AND THREE-MONTHS FOLLOW UP. RESULTS: CBT + YOGA WAS AN ACCEPTABLE ALTERNATIVE TO CBT ALONE. SIGNIFICANT REDUCTIONS WERE OBSERVED IN TOTAL DASS SCORES AND THE 3 SUBSCALES OF THE DASS FOR BOTH GROUPS, HOWEVER CBT + YOGA SHOWED SIGNIFICANTLY LOWER DEPRESSIVE AND ANXIETY SYMPTOMS POST-INTERVENTION, COMPARED TO CBT ALONE. CBT + YOGA ALSO SHOWED SUSTAINED REDUCTIONS IN DEPRESSIVE SYMPTOMS OVER THREE-MONTHS, AND MORE RAPID REDUCTIONS IN DEPRESSIVE SYMPTOMS, COMPARED TO CBT ALONE. LIMITATIONS: THESE FINDINGS SHOULD BE CONSIDERED PRELIMINARY DUE TO THE MODERATE SAMPLE SIZE, WITH A RIGOROUS RANDOMISED CONTROL TRIAL NECESSARY TO DEFINITIVELY SUPPORT THE INTEGRATION OF YOGA WITHIN MENTAL HEALTH CARE TO AUGMENT THE BENEFITS AND UPTAKE OF TRANSDIAGNOSTIC CBT FOR DEPRESSION AND ANXIETY. CONCLUSIONS: COMPLEMENTING OTHER MINDFULNESS-BASED PRACTICES, THERAPEUTIC YOGA SHOWS PROMISE AS AN ADJUNCT TO TRANSDIAGNOSTIC CBT.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
11  778 14 EFFECT OF YOGA AND WORKING MEMORY TRAINING ON COGNITIVE COMMUNICATIVE ABILITIES AMONG MIDDLE AGED ADULTS. SEVERAL STUDIES HAVE REPORTED IMPROVEMENTS IN COGNITIVE COMMUNICATIVE ABILITIES WITH WORKING MEMORY TRAINING AND ALTERNATIVE THERAPEUTIC METHODS CONDUCTED SEPARATELY. THE PRESENT STUDY AIMED TO INVESTIGATE THE EFFECTS OF COMBINING YOGA AND WORKING MEMORY TRAINING AMONG HEALTHY MIDDLE AGED ADULTS. A TOTAL OF 45 PARTICIPANTS WERE RANDOMLY ASSIGNED INTO THREE GROUPS. GROUP 1 RECEIVED BOTH YOGA AND WORKING MEMORY TRAINING, GROUP 2 RECEIVED ONLY WORKING MEMORY TRAINING AND GROUP 3 SERVED AS THE CONTROL GROUP. WORKING MEMORY TRAINING WAS PROVIDED ON SIX TASKS. YOGA TRAINING INVOLVED PRANAYAMAS AND MUDRAS. EFFECTS OF TRAINING WERE ASSESSED ALONG WITH THE SELF-PERCEPTUAL RATING OF THE PARTICIPANTS TOWARDS TRAINING. RESULTS REVEAL GREATER TRAINING EFFECTS AMONG GROUP 1 PARTICIPANTS, FOLLOWED BY GROUP 2 AND GROUP 3. GROUP 1 ALSO REPORTED BETTER PERCEPTION OF TRAINING (P < 0.05) THAN GROUP 2. THE STUDY HIGHLIGHTS THAT YOGA IS NOT ONLY AN ALTERNATIVE APPROACH, BUT ALSO AUGMENTATIVE IN IMPROVING COGNITIVE COMMUNICATIVE ABILITIES.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
12 1164 21 EVALUATING THE EFFECTS OF A YOGA-BASED PROGRAM INTEGRATED WITH THIRD-WAVE COGNITIVE BEHAVIORAL THERAPY COMPONENTS ON SELF-REGULATION IN CHILDREN ON THE AUTISM SPECTRUM: A PILOT RANDOMIZED CONTROLLED TRIAL. LAY ABSTRACT: CHILDREN ON THE AUTISM SPECTRUM MAY EXPERIENCE DIFFICULTIES WITH THE REGULATION OF ATTENTION, THOUGHTS, EMOTIONS, AND BEHAVIOR, UNDERSTANDING, AND EXPRESSING THEIR EMOTIONS APPROPRIATELY, AS WELL AS ANXIETY, AND SLEEP. IN AUTISM RESEARCH, CONTEMPLATIVE PRACTICES THAT WORK THROUGH BOTH BODY AND MIND HAVE SHOWN TENTATIVELY PROMISING RESULTS. HOWEVER, THERE ARE LIMITED STUDIES ON THIS TOPIC, AND THE USE OF YOGA TO FACILITATE EXECUTIVE CONTROL HAS NOT BEEN RESEARCHED YET. THE INCREDIBLE EXPLORERS (6-WEEK PROGRAM), A YOGA-INFORMED INTERVENTION PROGRAM FOR CHILDREN (8-12 YEARS), WAS DEVELOPED TO UNDERSTAND WHETHER, FOR CHILDREN ON THE AUTISM SPECTRUM, THE TRAINING COULD IMPROVE THE ABILITY TO SELF-REGULATE, REDUCE ANXIETY AND SLEEP PROBLEMS, AND INCREASE AWARENESS OF EMOTIONS. IN OUR SAMPLE, 61 CHILDREN WITH ONE OF THEIR PARENTS COMPLETED THE PROGRAM. HALF OF THE GROUP RECEIVED THE INTERVENTION, AND THE OTHER HALF HAD TO WAIT UNTIL THE YOGA GROUP COMPLETED THEIR TRIAL. THE PARTICIPANTS WERE ASKED TO GIVE THEIR FEEDBACK IMMEDIATELY AFTER PROGRAM COMPLETION AND AT 6-WEEK FOLLOW-UP. COMPARED TO THE GROUP THAT WAS WAITING TO RECEIVE THE INTERVENTION, PARENTS IN THE YOGA GROUP REPORTED SIGNIFICANT GAINS FOR THEIR CHILDREN IN REGULATING THEIR OVERALL EXECUTIVE CONTROL IMMEDIATELY AFTER THE SESSION AND AGAIN AT FOLLOW-UP. THE PARENTS REPORTED A REDUCTION IN SOME OF THE SLEEP PROBLEMS POST-TREATMENT. CHILDREN INDICATED AN IMPROVED ABILITY TO COMMUNICATE THEIR FEELINGS AND WILLINGNESS TO ANALYZE THEIR EMOTIONS POST-INTERVENTION. HOWEVER, THE STUDY HAD SEVERAL SHORTCOMINGS AND GIVEN THAT THIS WAS THE FIRST TRIAL OF THE PROGRAM, THE RESULTS NEED TO BE INTERPRETED WITH CAUTION. FURTHER RESEARCH IS RECOMMENDED.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
13  629 22 DIFFERENCES IN BRAIN STRUCTURE AND FUNCTION AMONG YOGA PRACTITIONERS AND CONTROLS. BACKGROUND: YOGA IS A MIND-BODY BASED PHYSICAL ACTIVITY THAT HAS DEMONSTRATED A VARIETY OF PHYSIOLOGICAL, PSYCHOLOGICAL AND COGNITIVE HEALTH BENEFITS. ALTHOUGH YOGA PRACTICE HAS SHOWN TO IMPROVE COGNITIVE PERFORMANCE, FEW STUDIES HAVE EXAMINED THE UNDERLYING NEUROLOGICAL CORRELATES. OBJECTIVE: THE CURRENT STUDY AIMED TO DETERMINE THE DIFFERENCES IN GRAY MATTER VOLUME OF THE HIPPOCAMPUS, THALAMUS AND CAUDATE NUCLEUS AND BRAIN ACTIVATION DURING THE STERNBERG WORKING MEMORY TASK. METHOD: PARTICIPANTS WERE 13 EXPERIENCED YOGA PRACTITIONERS (MEAN AGE = 35.8), DEFINED AS HAVING MORE THAN 3 YEARS OF REGULAR YOGA PRACTICE, AND 13 AGE- AND SEX-MATCHED CONTROLS (MEAN AGE = 35.7). ALL PARTICIPANTS COMPLETED A 6-MIN WALK TEST TO ASSESS FITNESS, PSYCHOSOCIAL AND DEMOGRAPHIC QUESTIONNAIRES; AND UNDERWENT MAGNETIC RESONANCE IMAGING TO ASSESS GRAY MATTER VOLUME AND BRAIN ACTIVATION. RESULTS: THERE WERE NO GROUP DIFFERENCES ON DEMOGRAPHIC MEASURES OF INCOME, EDUCATION AND ON ESTIMATED VO2MAX OR PHYSICAL ACTIVITY LEVELS. GRAY MATTER VOLUME DIFFERENCES WERE OBSERVED IN THE LEFT HIPPOCAMPUS, SHOWING GREATER VOLUME IN EXPERIENCED YOGA PRACTITIONERS COMPARED TO CONTROLS (P = 0.017). THE FUNCTIONAL MRI RESULTS REVEALED LESS ACTIVATION IN THE DORSOLATERAL PREFRONTAL CORTEX IN YOGA PRACTITIONERS COMPARED TO CONTROLS DURING THE ENCODING PHASE OF THE STERNBERG TASK (P < 0.05). REACTION TIME AND ACCURACY ON THE TASK DID NOT DIFFER BETWEEN THE GROUPS. CONCLUSIONS: OUR RESULTS SUGGEST AN ASSOCIATION BETWEEN REGULAR LONG-TERM YOGA PRACTICE AND DIFFERENTIAL STRUCTURE AND FUNCTION OF SPECIFIC BRAIN REGIONS INVOLVED IN EXECUTIVE FUNCTION, SPECIFICALLY WORKING MEMORY, WHICH HAS PREVIOUSLY SHOWN TO IMPROVE WITH YOGA PRACTICE. FUTURE STUDIES NEED TO EXAMINE INTERVENTION EFFECTS OF YOGA AND EXPLORE ITS POTENTIAL TO MAINTAIN AND IMPROVE COGNITIVE HEALTH ACROSS THE LIFESPAN THROUGH LONGITUDINAL AND INTERVENTION STUDIES.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
14 2520 21 YOGA COMPLEMENTS COGNITIVE BEHAVIOUR THERAPY AS AN ADJUNCT TREATMENT FOR ANXIETY AND DEPRESSION: QUALITATIVE FINDINGS FROM A MIXED-METHODS STUDY. OBJECTIVES: COGNITIVE BEHAVIOUR THERAPY (CBT) IS RECOMMENDED FOR TREATING ANXIETY AND DEPRESSION, DEMONSTRATING GOOD EFFICACY AND MODERATE RATES OF ENGAGEMENT. TO FURTHER IMPROVE OUTCOMES AND ACCESS TO EVIDENCE-BASED TREATMENTS, RESEARCHERS HAVE SOUGHT TO ENHANCE CBT PROTOCOLS WITH MINDFULNESS-BASED APPROACHES, SUCH AS YOGA. THIS STUDY AIMED TO EXAMINE WHETHER YOGA IS AN ACCEPTABLE AND COMPLEMENTARY ADJUNCT TO CBT THROUGH EXPLORING THE LIVED EXPERIENCES OF ADULTS WITH ANXIETY AND DEPRESSION WHO ENGAGED IN AN ADJUNCT THERAPEUTIC YOGA PROGRAMME ALONGSIDE GROUP CBT. DESIGN: SINGLE-GROUP QUALITATIVE DESIGN WITH POST-INTERVENTION AND FOLLOW-UP TIMEPOINTS. METHODS: THIRTY-SIX ADULTS WITH ANXIETY AND DEPRESSION SELF-SELECTED INTO A THERAPEUTIC YOGA PROGRAMME AS AN ADJUNCT TO GROUP CBT. QUALITATIVE INTERVIEWS WERE CONDUCTED WITH 27 PARTICIPANTS IMMEDIATELY AFTER THE EIGHT-WEEK PROGRAMME AND AGAIN THREE MONTHS LATER. THEMATIC ANALYSIS WAS USED TO IDENTIFY COMMON THEMES FROM THE LIVED EXPERIENCES. RESULTS: THREE PRIMARY THEMES, WITH NINE SUBTHEMES, WERE IDENTIFIED WHICH REFLECT THE EXPERIENCES OF THE COMBINED THERAPIES, THE COMPLEMENTARY ELEMENTS, AND PROCESS OF ENGAGEMENT OVER TIME. THE ADJUNCT YOGA PROGRAMME WAS HIGHLY ACCEPTABLE TO ADULTS WITH ANXIETY AND DEPRESSION, ENHANCING ENGAGEMENT AND PERCEIVED OUTCOMES. YOGA WAS IDENTIFIED AS PROVIDING A UNIQUE COMBINATION OF ELEMENTS THAT COMPLEMENTED PROCESSES OF CBT, SUCH AS BEHAVIOURAL ACTIVATION AND THOUGHT DISPUTATION. YOGA PRACTICES REPRESENTED MENTAL HEALTH SELF-MANAGEMENT TOOLS THAT ARE ACCESSIBLE AND AVAILABLE AS RELAPSE PREVENTION STRATEGIES. CONCLUSIONS: THERAPEUTIC YOGA WARRANTS CONSIDERATION AS AN ADJUNCT TREATMENT FOR ANXIETY AND DEPRESSION AS IT OFFERS UNIQUE AND COMPLEMENTARY ELEMENTS TO CBT AND CAN ENHANCE ENGAGEMENT AND PERCEIVED CLINICAL OUTCOMES. PRACTITIONER POINTS: ADULTS WITH ANXIETY AND DEPRESSION EXPERIENCED A THERAPEUTIC YOGA PROGRAMME AS A SUITABLE AND APPEALING ADJUNCT THAT ENHANCED ENGAGEMENT WITH PSYCHOLOGICAL TREATMENT. YOGA OFFERS A UNIQUE COMBINATION OF ELEMENTS, INCLUDING A VALUES SYSTEM, BODY-BASED MINDFULNESS PRACTICES, AND BREATHING TECHNIQUES, THAT COMPLEMENT CBT PROCESSES, SUCH AS BEHAVIOURAL ACTIVATION, AWARENESS OF MALADAPTIVE PATTERNS, AND THOUGHT DISPUTATION. A THERAPEUTIC YOGA PROGRAMME PROVIDES ADULTS WITH ANXIETY AND DEPRESSION WITH AN ACCESSIBLE AND SUSTAINABLE MENTAL HEALTH SELF-MANAGEMENT TOOL. THERAPEUTIC YOGA CAN BE CONSIDERED FOR INTEGRATION TO MODELS OF MENTAL HEALTH SERVICE PROVISION TO ENHANCE ENGAGEMENT AND CLINICAL OUTCOMES FOR ADULTS WITH ANXIETY AND DEPRESSION.	2021	

15 2577 25 YOGA FOR GENERALIZED ANXIETY DISORDER: DESIGN OF A RANDOMIZED CONTROLLED CLINICAL TRIAL. GENERALIZED ANXIETY DISORDER (GAD) IS A COMMON DISORDER ASSOCIATED WITH SIGNIFICANT DISTRESS AND INTERFERENCE. ALTHOUGH COGNITIVE BEHAVIORAL THERAPY (CBT) HAS BEEN SHOWN TO BE THE MOST EFFECTIVE FORM OF PSYCHOTHERAPY, FEW PATIENTS RECEIVE OR HAVE ACCESS TO THIS INTERVENTION. YOGA THERAPY OFFERS ANOTHER PROMISING, YET UNDER-RESEARCHED, INTERVENTION THAT IS GAINING INCREASING POPULARITY IN THE GENERAL PUBLIC, AS AN ANXIETY REDUCTION INTERVENTION. THE PURPOSE OF THIS INNOVATIVE CLINICAL TRIAL PROTOCOL IS TO INVESTIGATE THE EFFICACY OF A KUNDALINI YOGA INTERVENTION, RELATIVE TO CBT AND A CONTROL CONDITION. KUNDALINI YOGA AND CBT ARE COMPARED WITH EACH OTHER IN A NONINFERIORITY TEST AND BOTH TREATMENTS ARE COMPARED TO STRESS EDUCATION TRAINING, AN ATTENTION CONTROL INTERVENTION, IN SUPERIORITY TESTS. THE SAMPLE WILL CONSIST OF 230 INDIVIDUALS WITH A PRIMARY DSM-5 DIAGNOSIS OF GAD. THIS RANDOMIZED CONTROLLED TRIAL WILL COMPARE YOGA (N=95) TO BOTH CBT FOR GAD (N=95) AND STRESS EDUCATION (N=40), A COMMONLY USED CONTROL CONDITION. ALL THREE TREATMENTS WILL BE ADMINISTERED BY TWO INSTRUCTORS IN A GROUP FORMAT OVER 12 WEEKLY SESSIONS WITH FOUR TO SIX PATIENTS PER GROUP. GROUPS WILL BE RANDOMIZED USING PERMUTED BLOCK RANDOMIZATION, WHICH WILL BE STRATIFIED BY SITE. TREATMENT OUTCOME WILL BE EVALUATED BI-WEEKLY AND AT 6MONTH FOLLOW-UP. FURTHERMORE, POTENTIAL MEDIATORS OF TREATMENT OUTCOME WILL BE INVESTIGATED. GIVEN THE INDIVIDUAL AND ECONOMIC BURDEN ASSOCIATED WITH GAD, IDENTIFYING ACCESSIBLE ALTERNATIVE BEHAVIORAL TREATMENTS WILL HAVE SUBSTANTIVE PUBLIC HEALTH IMPLICATIONS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
16 2369 23 WHAT ARE THE KNOWN EFFECTS OF YOGA ON THE BRAIN IN RELATION TO MOTOR PERFORMANCES, BODY AWARENESS AND PAIN? A NARRATIVE REVIEW. OBJECTIVE: THE CURRENT BODY OF LITERATURE WAS REVIEWED TO EVALUATE THE EFFECTS OF YOGA ON THE BRAIN IN RELATION TO MOTOR PERFORMANCE, BODY AWARENESS AND PAIN. BACKGROUND: YOGA HAS BEEN INCREASINGLY POPULAR IN THE WESTERN COUNTRIES ESPECIALLY FOR ITS UNIQUE INTEGRATION OF THE MIND AND BODY. YOGA HAS BEEN STUDIED MORE INTENSELY IN THE LAST DECADE. ALTHOUGH IT HAS BEEN SHOWN TO IMPROVE COGNITIVE FUNCTIONS, FEW STUDIES HAVE LOOKED INTO THE EFFECTS OF YOGA ON IMPROVING MOTOR PERFORMANCE, BODY AWARENESS OR PAIN AND THE POSSIBLE UNDERLYING BRAIN MECHANISMS ASSOCIATED WITH THEM. METHODS: A SEARCH OF THE CURRENT LITERATURE WAS MADE USING KEYWORDS SUCH AS: "YOGA BRAIN MOTOR", "YOGA BRAIN PAIN", "EFFECTS YOGA BRAIN" AND "EFFECTS YOGA BRAIN MOTOR PERFORMANCE". THE FINDINGS WERE THEN DISCUSSED IN RELATION TO MOTOR PERFORMANCE, BODY AWARENESS AND PAIN AND THEIR REPORTED MECHANISMS OF ACTION ON THE BRAIN. RESULTS: A TOTAL OF 61 ARTICLES WERE SELECTED, OUT OF WHICH 29 WERE EXCLUDED BECAUSE THEY DID NOT MEET OUR CRITERIA. A TOTAL OF THIRTY-TWO ARTICLES WERE INCLUDED IN THIS REVIEW, WHICH WE FURTHER SUBDIVIDED BY FOCUS: MOTOR PERFORMANCE (N=10), BODY AWARENESS (N=14) AND PAIN (N=8). DISCUSSION: OUR REVIEW SHOWS THAT YOGA HAS A POSITIVE EFFECT ON LEARNING RATE, SPEED AND ACCURACY OF A MOTOR TASK BY INCREASING ATTENTION AND DECREASING STRESS THROUGH A BETTER CONTROL OF SENSORIMOTOR RHYTHMS. YOGA ALSO SEEMS TO IMPROVE SENSORY AWARENESS AND INTEROCEPTION, REGULATE AUTONOMIC INPUT, INCREASE PARASYMPATHETIC ACTIVITY AND PROMOTE SELF-REGULATION. YOGA WAS ALSO SHOWN TO REDUCE THE THREAT SIGNAL, INCREASE PAIN TOLERANCE, DECREASE PAIN UNPLEASANTNESS AND DECREASE THE ANXIETY AND DISTRESS ASSOCIATED WITH PAIN. THOSE CHANGES ARE ASSOCIATED WITH THE RECRUITMENT OF SPECIFIC BRAIN AREAS SUCH AS THE INSULA, THE AMYGDALA AND THE HIPPOCAMPUS. CONCLUSION: BASED ON THE STUDIES REVIEWED IN THIS REPORT, WE FOUND THAT THE PRACTICE OF YOGA SEEMS TO FACILITATE MOTOR LEARNING, TO INCREASE BODY AWARENESS AND TO DECREASE PAIN. THESE ARE ASSOCIATED WITH A WIDE VARIETY OF CHANGES IN TERMS OF BRAIN ACTIVITY AND STRUCTURE. FURTHER STUDIES ARE NECESSARY TO REVEAL ITS PRECISE MECHANISM OF ACTION ON THE BRAIN AND TO VALIDATE ITS WIDER APPLICATION IN CLINICAL SETTINGS.	2019	
                                                                                                                                                                                                                                                                                                                                                                            
17 1668 17 NEUROCOGNITIVE CORRELATES OF THE EFFECTS OF YOGA MEDITATION PRACTICE ON EMOTION AND COGNITION: A PILOT STUDY. MINDFULNESS MEDITATION INVOLVES ATTENDING TO EMOTIONS WITHOUT COGNITIVE FIXATION OF EMOTIONAL EXPERIENCE. OVER TIME, THIS PRACTICE IS HELD TO PROMOTE ALTERATIONS IN TRAIT AFFECTIVITY AND ATTENTIONAL CONTROL WITH RESULTANT EFFECTS ON WELL-BEING AND COGNITION. HOWEVER, RELATIVELY LITTLE IS KNOWN REGARDING THE NEURAL SUBSTRATES OF MEDITATION EFFECTS ON EMOTION AND COGNITION. THE PRESENT STUDY INVESTIGATED THE NEUROCOGNITIVE CORRELATES OF EMOTION INTERFERENCE ON COGNITION IN YOGA PRACTITIONERS AND A MATCHED CONTROL GROUP (CG) UNDERWENT FMRI WHILE PERFORMING AN EVENT-RELATED AFFECTIVE STROOP TASK. THE TASK INCLUDES IMAGE VIEWING TRIALS AND STROOP TRIALS BRACKETED BY NEUTRAL OR NEGATIVE EMOTIONAL DISTRACTORS. DURING IMAGE VIEWING TRIALS, YOGA PRACTITIONERS EXHIBITED LESS REACTIVITY IN RIGHT DORSOLATERAL PREFRONTAL CORTEX (DLPFC) TO NEGATIVE AS COMPARED TO NEUTRAL IMAGES; WHEREAS THE CG HAD THE OPPOSITE PATTERN. A MAIN EFFECT OF VALENCE (NEGATIVE > NEUTRAL) WAS OBSERVED IN LIMBIC REGIONS (E.G., AMYGDALA), OF WHICH THE MAGNITUDE WAS INVERSELY RELATED TO DLPFC ACTIVATION. EXPLORATORY ANALYSES REVEALED THAT THE MAGNITUDE OF AMYGDALA ACTIVATION PREDICTED DECREASED SELF-REPORTED POSITIVE AFFECT IN THE CG, BUT NOT AMONG YOGA PRACTITIONERS. DURING STROOP TRIALS, YOGA PRACTITIONERS HAD GREATER ACTIVATION IN VENTROLATERAL PREFRONTAL CORTEX (VLPFC) DURING STROOP TRIALS WHEN NEGATIVE, COMPARED TO NEUTRAL, EMOTIONAL DISTRACTOR WERE PRESENTED; THE CG EXHIBITED THE OPPOSITE PATTERN. TAKEN TOGETHER, THESE DATA SUGGEST THAT THOUGH YOGA PRACTITIONERS EXHIBIT LIMBIC REACTIVITY TO NEGATIVE EMOTIONAL STIMULI, SUCH REACTIVITY DOES NOT HAVE DOWNSTREAM EFFECTS ON LATER MOOD STATE. THIS UNCOUPLING OF VIEWING NEGATIVE EMOTIONAL IMAGES AND AFFECT AMONG YOGA PRACTITIONERS MAY BE OCCASIONED BY THEIR SELECTIVE IMPLEMENTATION OF FRONTAL EXECUTIVE-DEPENDENT STRATEGIES TO REDUCE EMOTIONAL INTERFERENCE DURING COMPETING COGNITIVE DEMANDS AND NOT DURING EMOTIONAL PROCESSING PER SE.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
18  288 19 ADJUNCTIVE COGNITIVE REMEDIATION FOR SCHIZOPHRENIA USING YOGA: AN OPEN, NON-RANDOMIZED TRIAL. BACKGROUND: YOGA THERAPY (YT) IMPROVES COGNITIVE FUNCTION IN HEALTHY INDIVIDUALS, BUT ITS IMPACT ON COGNITIVE FUNCTION AMONG PERSONS WITH SCHIZOPHRENIA (SZ) HAS NOT BEEN INVESTIGATED. AIMS: EVALUATE ADJUNCTIVE YT FOR COGNITIVE DOMAINS IMPAIRED IN SZ. METHODS: PATIENTS WITH SZ RECEIVED YT OR TREATMENT AS USUAL (TAU; N = 65, N = 23, RESPECTIVELY). ACCURACY AND SPEED FOR SEVEN COGNITIVE DOMAINS WERE ASSESSED USING A COMPUTERIZED NEUROCOGNITIVE BATTERY (CNB), THUS MINIMIZING OBSERVER BIAS. SEPARATELY, YT WAS EVALUATED AMONG PATIENTS WITH BIPOLAR I DISORDER (N = 40), MAJOR DEPRESSIVE DISORDER (N = 37), AND CARDIOLOGY OUTPATIENTS (N = 68). ALL PATIENTS ALSO RECEIVED ROUTINE PHARMACOTHERAPY. PATIENTS WERE NOT RANDOMIZED TO YT OR TAU. RESULTS: COMPARED WITH THE SZ/TAU GROUP, THE SZ/YT GROUP SHOWED SIGNIFICANTLY GREATER IMPROVEMENT WITH REGARD TO MEASURES OF ATTENTION FOLLOWING CORRECTIONS FOR MULTIPLE COMPARISONS; THE CHANGES WERE MORE PROMINENT AMONG THE MEN. IN THE OTHER DIAGNOSTIC GROUPS, DIFFERING PATTERNS OF IMPROVEMENTS WERE NOTED WITH SMALL TO MEDIUM EFFECT SIZES. CONCLUSIONS: OUR INITIAL ANALYSES SUGGEST NOMINALLY SIGNIFICANT IMPROVEMENT IN COGNITIVE FUNCTION IN SCHIZOPHRENIA WITH ADJUNCTIVE THERAPIES SUCH AS YT. THE MAGNITUDE OF THE CHANGE VARIES BY COGNITIVE DOMAIN AND MAY ALSO VARY BY DIAGNOSTIC GROUP.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
19 2743 23 YOGA PRACTICE IMPROVES EXECUTIVE FUNCTION BY ATTENUATING STRESS LEVELS. BACKGROUND: PROLONGED ACTIVATION OF THE HYPOTHALAMUS-PITUITARY-ADRENAL SYSTEM IS THOUGHT TO HAVE DELETERIOUS EFFECTS ON BRAIN FUNCTION. NEUROENDOCRINE STUDIES SUGGEST THAT BRAIN EXPOSURE TO HIGHER CORTISOL CONCENTRATIONS CONTRIBUTE TO COGNITIVE DEFICITS AS WE AGE. MIND-BODY TECHNIQUES SUCH AS YOGA HAVE SHOWN TO IMPROVE STRESS LEVELS BY RESTORING THE BODY'S SYMPATHETIC-PARASYMPATHETIC BALANCE. THE OBJECTIVE OF THIS STUDY WAS TO DETERMINE WHETHER YOGA PRACTICE MODERATED THE STRESS RESPONSE RESULTING IN IMPROVED EXECUTIVE FUNCTION. METHODS: SEDENTARY COMMUNITY DWELLING OLDER ADULTS (N=118, MEAN AGE=62.02) WERE RANDOMIZED TO AN 8-WEEK YOGA INTERVENTION OR A STRETCHING CONTROL GROUP. AT BASELINE AND FOLLOWING 8 WEEKS, ALL PARTICIPANTS COMPLETED MEASURES OF EXECUTIVE FUNCTION, SELF-REPORTED STRESS AND ANXIETY AND PROVIDED SALIVA SAMPLES BEFORE AND AFTER COGNITIVE TESTING TO ASSESS CORTISOL. RESULTS: YOGA PARTICIPANTS SHOWED IMPROVED ACCURACY ON EXECUTIVE FUNCTION MEASURES AND AN ATTENUATED CORTISOL RESPONSE COMPARED TO THEIR STRETCHING COUNTERPARTS WHO SHOWED INCREASED CORTISOL LEVELS AND POOR COGNITIVE PERFORMANCE AT FOLLOW UP. THE CHANGE IN CORTISOL LEVELS AS WELL AS SELF-REPORTED STRESS AND ANXIETY LEVELS PREDICTED PERFORMANCE ON THE RUNNING SPAN TASK, N-BACK WORKING MEMORY AND TASK SWITCHING PARADIGM (BETA'S=0.27-0.38, P'S</=0.05 FOR YOGA AND BETA'S=-0.37-0.47, P'S</=0.01 FOR STRETCHING CONTROL). CONCLUSION: EIGHT WEEKS OF REGULAR YOGA PRACTICE RESULTED IN IMPROVED WORKING MEMORY PERFORMANCE THAT WAS MEDIATED BY AN ATTENUATED RESPONSE TO STRESS AS MEASURED BY SELF-REPORT STRESS AND OBJECTIVE SALIVARY CORTISOL MEASUREMENTS. THIS TRIAL OFFERS EVIDENCE FOR NON-TRADITIONAL PHYSICAL ACTIVITY INTERVENTIONS SUCH AS YOGA THAT MAY BE HELPFUL IN RESTORING HPA BALANCE IN OLDER ADULTS, THEREBY PREVENTING COGNITIVE DECLINE.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
20  542 22 COMPUTERIZED COGNITIVE TRAINING (CCT) VERSUS YOGA IMPACT ON 12 MONTH POST INTERVENTION COGNITIVE OUTCOME IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT. THERE IS CURRENTLY LIMITED AND MIXED EVIDENCE FOR THE COGNITIVE BENEFITS OF COMPUTERIZED COGNITIVE TRAINING (CCT) AND YOGA IN PERSONS WITH MILD COGNITIVE IMPAIRMENT (PWMCI). THE OBJECTIVE OF THIS STUDY WAS TO INVESTIGATE THE BENEFIT OF COMPUTERIZED COGNITIVE TRAINING (CCT) VS. PHYSICAL (YOGA) INTERVENTION ON COGNITIVE ABILITIES. PARTICIPANTS IN THIS STUDY WERE PART OF THE LARGER MAYO CLINIC'S HEALTHY ACTION TO BENEFIT INDEPENDENCE AND THINKING (HABIT) PROGRAM COMPARATIVE EFFECTIVENESS TRIAL. THE HABIT PROGRAM IS DESIGNED FOR PWMCI AND THEIR CARE PARTNER AND CONSISTS OF FIVE BEHAVIORAL INTERVENTIONS: CCT, MEMORY SUPPORT SYSTEM-CALENDAR (MSS-CALENDAR), WELLNESS EDUCATION, SUPPORT GROUPS, AND YOGA. THE SUBTRACTIVE STUDY DESIGN RANDOMLY WITHHELD ONE OF THE INTERVENTIONS FOR A TOTAL OF FIVE STUDY ARMS. LONGITUDINAL MIXED-EFFECTS REGRESSION MODELS WERE USED TO INVESTIGATE THE HYPOTHESIS THAT CCT AND YOGA HAS A GREATER POSITIVE IMPACT ON PSYCHOMOTOR AND BASIC ATTENTION ABILITIES AT 12 MONTHS POST-INTERVENTION AS COMPARED TO THE OTHER HABIT INTERVENTIONS. FINDINGS SHOWED CCT HAD A POSITIVE IMPACT COMPARED TO YOGA ON THE COGSTATE PSYCHOMOTOR/ATTENTION COMPOSITE AT 12 MONTHS POST-INTERVENTION (ES = 0.54; UNADJUSTED P VALUE = 0.007, ADJUSTED P VALUE = 0.021). THE IMPACT OF YOGA OR COMBINING CCT WITH YOGA DID NOT SHOW STATISTICALLY SIGNIFICANT IMPROVEMENT. CONTINUED CCT PRACTICE AT HOME SHOWED FURTHER BENEFIT ON PSYCHOMOTOR/ATTENTION AT 12 MONTHS POST-INTERVENTION. THERE WAS NO SIGNIFICANT BENEFIT OF CCT OR YOGA ON COGSTATE LEARNING/WORKING MEMORY COMPOSITE.	2021