1 2333 96 TWELVE-MINUTE DAILY YOGA REGIMEN REVERSES OSTEOPOROTIC BONE LOSS. OBJECTIVE: ASSESS THE EFFECTIVENESS OF SELECTED YOGA POSTURES IN RAISING BONE MINERAL DENSITY (BMD). METHODS: TEN-YEAR STUDY OF 741 INTERNET-RECRUITED VOLUNTEERS COMPARING PREYOGA BMD CHANGES WITH POSTYOGA BMD CHANGES. OUTCOME MEASURES: DUAL-ENERGY X-RAY ABSORPTIOMETRIC SCANS. OPTIONAL RADIOGRAPHS OF HIPS AND SPINE AND BONE QUALITY STUDY (7 TESLA). RESULTS: BONE MINERAL DENSITY IMPROVED IN SPINE, HIPS, AND FEMUR OF THE 227 MODERATELY AND FULLY COMPLIANT PATIENTS. MONTHLY GAIN IN BMD WAS SIGNIFICANT IN SPINE (0.0029 G/CM(2), P = .005) AND FEMUR (0.00022 G/CM(2), P = .053), BUT IN 1 COHORT, ALTHOUGH MEAN GAIN IN HIP BMD WAS 50%, LARGE INDIVIDUAL DIFFERENCES RAISED THE CONFIDENCE INTERVAL AND THE GAIN WAS NOT SIGNIFICANT FOR TOTAL HIP (0.000357 G/CM(2)). NO YOGA-RELATED SERIOUS INJURIES WERE IMAGED OR REPORTED. BONE QUALITY APPEARED QUALITATIVELY IMPROVED IN YOGA PRACTITIONERS. CONCLUSION: YOGA APPEARS TO RAISE BMD IN THE SPINE AND THE FEMUR SAFELY.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
2 1111 27 EFFECTS OF YOGASANAS ON OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN. BACKGROUND: OSTEOPOROSIS IS COMMONLY ENCOUNTERED BY POSTMENOPAUSAL WOMEN. THERE IS AN INCREASED NEED FOR A LOW COST AND EFFICIENT TREATMENT ALTERNATIVE TO ADDRESS THIS POPULATION. AIMS: TO STUDY THE EFFECTS OF INTEGRATED YOGA ON BONE MINERAL DENSITY (BMD) IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS. SETTINGS AND DESIGNS: EXPERIMENTAL PRE-POST STUDY CONDUCTED IN A COMMUNITY SETTING. MATERIALS AND METHODS: 30 FEMALES IN THE AGE GROUP OF 45-62 YEARS SUFFERING FROM POSTMENOPAUSAL OSTEOPOROSIS WITH A DUAL-ENERGY X-RAY ABSORPTIOMETRY (DEXA) SCORE OF </=-2.5 UNDERWENT A 6 MONTHS FULLY SUPERVISED YOGA SESSION. ALL THE PARTICIPANTS COMPLETED THE STUDY. PRETRAINING AND POSTTRAINING BMD WAS CALCULATED. OUTCOME MEASURE: DEXA SCORE AT THE LUMBAR SPINE. STATISTICAL ANALYSIS: THE STUDY WAS STATISTICALLY ANALYZED USING PAIRED T-TEST TO SEE THE SIGNIFICANCE OF PRETRAINING AND POSTTRAINING EFFECTS OF A YOGA SESSION. RESULTS: IMPROVEMENT IN T-SCORE OF DEXA SCAN OF -2.55 +/- 0.25 AT POSTTRAINING AS COMPARED TO A PRETRAINING SCORE OF -2.69 +/- 0.17. CONCLUSIONS: INTEGRATED YOGA IS A SAFE MODE OF PHYSICAL ACTIVITY WHICH INCLUDES WEIGHT BEARING AS WELL AS NOT WEIGHT BEARING ASANAS, PRANAYAMA, AND SURYANAMASKAR, ALL OF WHICH HELPS INDUCE IMPROVEMENT IN BMD IN POSTMENOPAUSAL OSTEOPOROTIC FEMALES.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
3 2359 19 VERTEBRAL COMPRESSION FRACTURES ASSOCIATED WITH YOGA: A CASE SERIES. BACKGROUND: THE IMPORTANCE OF EXERCISE IN SKELETAL HEALTH IS INCREASINGLY RECOGNIZED BY BOTH PATIENTS AND PROVIDERS. HOWEVER, THE SAFETY OF PRESCRIBED OR RECREATIONAL EXERCISE IN AT-RISK POPULATIONS REMAINS UNDER-REPORTED AND UNDER-PUBLICIZED. YOGA HAS GAINED WIDESPREAD POPULARITY DUE TO ITS PHYSICAL AND PSYCHOLOGICAL BENEFITS. WHEN PRACTICED IN A POPULATION AT INCREASED FRACTURE RISK, HOWEVER, SOME YOGA POSES MAY INCREASE FRACTURE RISK, PARTICULARLY AT THE SPINE, RATHER THAN INCREASING BMD AS NOTED IN RECENT POPULAR PRESS REPORTS. CASE REPORT: NINE SUBJECTS (8 WOMEN) WITH A MEDIAN AGE OF 66 YEARS (RANGE 53-87), DEVELOPED VERTEBRAL COMPRESSION FRACTURE (VCF) ONE MONTH TO SIX YEARS AFTER INITIATING YOGA-ASSOCIATED SPINAL FLEXION EXERCISES (SFE). VCF PRESENTED WITH BACK PAIN AND OCCURRED IN THE THORACICSPINE (N.=6), LUMBAR-SPINE (N.=4) AND CERVICAL-SPINE (N.=1). FOUR PATIENTS HAD OSTEOPOROSIS BY BMD CRITERIA PRIOR TO VCF AND 2 HAD OSTEOPENIA (MEDIAN T-SCORE -2.35; RANGE -3.3 TO +2.0). INTERESTINGLY, ALL PATIENTS HAD THEIR LOWEST T-SCORES AT THE SPINE. THREE PATIENTS HAD A HISTORY OF FRAGILITY FRACTURE PRIOR TO THE INDEX VCF. WHILE ONE PATIENT HAD PRIMARY HYPERPARATHYROIDISM AND ANOTHER WAS TREATED WITH HIGH DOSE PREDNISONE, NO OTHER RISK FACTORS FOR BONE LOSS INCLUDING MEDICATIONS OR SECONDARY OSTEOPOROSIS CAUSES WERE IDENTIFIED IN THE OTHER PATIENTS. CLINICAL REHABILITATION IMPACT: THIS STUDY IDENTIFIED PATIENTS IN WHOM INCREASED TORSIONAL AND COMPRESSIVE MECHANICAL LOADING PRESSURES OCCURRING DURING YOGA SFE RESULTED IN DE NOVO VCF. DESPITE THE NEED FOR SELECTIVITY IN YOGA POSES IN POPULATIONS AT INCREASED FRACTURE RISK, BOTH SCIENTIFIC AND MEDIA REPORTS CONTINUE TO ADVERTISE YOGA AS A BONE PROTECTIVE ACTIVITY. ACCORDINGLY, YOGA IS MISCONCEIVED AS A 'ONESIZE-FITS-ALL' PRESCRIPTION. INSTEAD, THE APPROPRIATE SELECTION OF PATIENTS LIKELY TO BENEFIT FROM YOGA MUST BE A CORNERSTONE OF FRACTURE PREVENTION.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
4  914 28 EFFECTIVENESS OF PILATES AND YOGA TO IMPROVE BONE DENSITY IN ADULT WOMEN: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: THE AGEING POPULATION BRINGS ABOUT THE APPEARANCE OF AGE-RELATED HEALTH DISORDERS, SUCH AS OSTEOPOROSIS OR OSTEOPENIA. THESE DISORDERS ARE ASSOCIATED WITH FRAGILITY FRACTURES. THE IMPACT IS GREATER AMONG POSTMENOPAUSAL WOMEN DUE TO AN ACCELERATION OF BONE MINERAL DENSITY (BMD) LOSS. OBJECTIVE: TO ESTIMATE THE EFFECTIVENESS OF PILATES OR YOGA ON BMD IN ADULT WOMEN. METHODS: FIVE ELECTRONICS DATABASES WERE SEARCHED UP TO APRIL 2021. RANDOMIZED CONTROLLED TRIALS (RCTS), NON-RCTS AND PRE-POST STUDIES WERE INCLUDED. THE MAIN OUTCOME WAS BMD. RISK OF BIAS WAS EVALUATED USING THE COCHRANE RISK OF BIAS TOOL. A RANDOM EFFECTS MODEL WAS USED TO POOL DATA FROM PRIMARY STUDIES. SUBGROUP ANALYSES BASED ON THE TYPE OF EXERCISE WERE CONDUCTED. RESULTS: ELEVEN STUDIES INCLUDING 591 PARTICIPANTS AGED BETWEEN 45 AND 78 YEARS WERE INCLUDED. THE MEAN LENGTH OF THE INTERVENTIONS RANGED FROM 12 TO 32 WEEKS, AND TWO STUDIES WERE PERFORMED FOR A PERIOD OF AT LEAST ONE YEAR. THE POOLED EFFECT SIZE FOR THE EFFECT OF THE INTERVENTION (PILATES/YOGA) VS THE CONTROL GROUP WAS 0.07 (95% CONFIDENCE INTERVAL [CI]: -0.05 TO 0.19; I2 = 0.0%), AND 0.10 (95% CI: 0.01 TO 0.18; I2 = 18.4%) FOR THE SECONDARY ANALYSIS OF THE PRE-POST INTERVENTION. CONCLUSIONS: DESPITE OF THE NON-SIGNIFICANT RESULTS, THE BMD MAINTENANCE IN THE POSTMENOPAUSAL POPULATION, WHEN BMD DETRIMENTAL IS EXPECTED, COULD BE UNDERSTOOD AS A POSITIVE RESULT ADDED TO THE BENEFICIAL IMPACT OF PILATES-YOGA IN MULTIPLE FRACTURE RISK FACTORS, INCLUDING BUT NOT LIMITED TO, STRENGTH AND BALANCE.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
5 2777 26 YOGA SPINAL FLEXION POSITIONS AND VERTEBRAL COMPRESSION FRACTURE IN OSTEOPENIA OR OSTEOPOROSIS OF SPINE: CASE SERIES. OBJECTIVE: THE OBJECTIVE OF THIS REPORT IS TO RAISE AWARENESS OF THE EFFECT OF STRENUOUS YOGA FLEXION EXERCISES ON OSTEOPENIC OR OSTEOPOROTIC SPINES. WE PREVIOUSLY DESCRIBED SUBJECTS WITH KNOWN OSTEOPOROSIS IN WHOM VERTEBRAL COMPRESSION FRACTURES (VCFS) DEVELOPED AFTER SPINAL FLEXION EXERCISE (SFE) AND RECOMMENDED THAT SFES NOT BE PRESCRIBED IN PATIENTS WITH SPINAL OSTEOPOROSIS. METHODS: THIS REPORT DESCRIBES 3 HEALTHY PERSONS WITH LOW BONE MASS AND YOGA-INDUCED PAIN OR FRACTURE. RESULTS: ALL 3 PATIENTS HAD OSTEOPENIA, WERE IN GOOD HEALTH AND PAIN-FREE, AND HAD STARTED YOGA EXERCISES TO IMPROVE THEIR MUSCULOSKELETAL HEALTH. NEW PAIN AND FRACTURE AREAS OCCURRED AFTER PARTICIPATION IN YOGA FLEXION EXERCISES. CONCLUSIONS: THE DEVELOPMENT OF PAIN AND COMPLICATIONS WITH SOME FLEXION YOGA POSITIONS IN THE PATIENTS WITH OSTEOPENIA LEADS TO CONCERN THAT FRACTURE RISK WOULD INCREASE EVEN FURTHER IN OSTEOPOROSIS. ALTHOUGH EXERCISE HAS BEEN SHOWN TO BE EFFECTIVE FOR IMPROVING BONE MINERAL DENSITY AND DECREASING FRACTURE RISK, OUR SUBJECTS HAD DEVELOPMENT OF VCFS AND NECK AND BACK PAIN WITH YOGA EXERCISES. THIS FINDING SUGGESTS THAT FACTORS OTHER THAN BONE MASS SHOULD BE CONSIDERED FOR EXERCISE COUNSELING IN PATIENTS WITH BONE LOSS. THE INCREASED TORQUE PRESSURE APPLIED TO VERTEBRAL BODIES DURING SFES MAY BE A RISK. EXERCISE IS EFFECTIVE AND IMPORTANT FOR TREATMENT OF OSTEOPENIA AND OSTEOPOROSIS AND SHOULD BE PRESCRIBED FOR PATIENTS WITH VERTEBRAL BONE LOSS. SOME YOGA POSITIONS CAN CONTRIBUTE TO EXTREME STRAIN ON SPINES WITH BONE LOSS. ASSESSMENT OF FRACTURE RISK IN OLDER PERSONS PERFORMING SFES AND OTHER HIGH-IMPACT EXERCISES IS AN IMPORTANT CLINICAL CONSIDERATION.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
6 2160 21 THE EFFECTS OF WEIGHT BEARING YOGA TRAINING ON THE BONE RESORPTION MARKERS OF THE POSTMENOPAUSAL WOMEN. THIS STUDY WAS A PRELIMINARY REPORT TO INVESTIGATE THE EFFECTS OF THE WEIGHT BEARING YOGA TRAINING ON BOTH BONE RESORPTION MARKER AND THE QUALITY OF LIFE OF THE POSTMENOPAUSAL WOMEN. THE SAMPLES WERE RECRUITED BY THE PURPOSIVE SAMPLING FROM THE FEMALE CHULALONGKORN UNIVERSITY STAFF AGED BETWEEN 50-60 YEARS. THE SUBJECTS WERE DIVIDED INTO TWO GROUPS: EXPERIMENTAL GROUP AND CONTROL GROUP. THE BASELINE DEMOGRAPHIC DATA, THE BONE RESORPTION MARKER (BETA-CROSSLAPS), THE BONE FORMATION MARKER (P1NP) AND QUALITY OF LIFE (SF-36) DATA WERE COLLECTED. THE EXPERIMENTAL GROUP ATTENDED THE 12-WEEK WEIGHT-BEARING YOGA TRAINING 3 DAYS A WEEK, 50 MINUTES A DAY WHILE THE CONTROL GROUP LIVED THEIR NORMAL LIVES. AFTER 12TH WEEK, THE DATA COLLECTIONS WERE REPEATED IN BOTH GROUPS. THE EXPERIMENTAL GROUP (19 SUBJECTS, THE MEAN AGE 54.320 YRS) AND THE CONTROL GROUP (14 SUBJECTS, THE MEAN AGE 54.430 YRS) WERE RECRUITED. THE MEAN ULTRASOUND BMD OF BOTH HEELS IN BOTH GROUPS SHOWED NO OSTEOPENIA OR OSTEOPOROSIS. AFTER THE 12-WEEK TRAINING, THE MEAN BONE RESORPTION MARKER (BETA-CROSSLAPS) OF THE EXPERIMENTAL GROUP REDUCED FROM 0.464 TO 0.339 NG/ML (-26.939%) WHEREAS THE CONTROL GROUP REDUCED FROM 0.389 TO 0.386 NG/ML (-0.771%). THERE WAS A SIGNIFICANT DIFFERENCE (P < 0.05). THE MEAN OF THE BONE FORMATION MARKERS (PINP) IN THE EXPERIMENTAL GROUP REDUCED FROM 55.393 TO 42.401 NG/ML (-23.454%) AND THE BONE FORMATION MARKERS (PINP) IN THE CONTROL GROUP REDUCED FROM 61.903 TO 44.832 NG/ML (-27.577%). IN THE AREA OF THE LIFE QUALITY MEASUREMENT OF BOTH GROUPS, THE DATA OBTAINED FROM THE MEDICAL OUTCOMES STUDY SHORT-FORM SURVEY (SF-36) SHOWED THAT THERE WERE SIGNIFICANT DIFFERENCES AT 0.05 LEVELS FOR THE PHYSICAL FUNCTIONING, BODILY PAIN, GENERAL HEALTH, AND VITALITY. THE VARIANCE OF PERCENTAGE CHANGE VALUE OF THE EXPERIMENTAL GROUP INCREASED TO +25.299, +16.565, +15.309, AND +21.056. THE VARIANCE OF PERCENTAGE CHANGE VALUE OF THE CONTROL GROUP INCREASED TO +12.946, -1.221, -9.303 AND +2.291. THE WEIGH-BEARING YOGA TRAINING HAD A POSITIVE EFFECT ON BONE BY SLOWING DOWN BONE RESORPTION WHICH WAS A VERY ESSENTIAL INDICATOR FOR HUMAN HEALTH BECAUSE IT REDUCED THE OSTEOPOROSIS RISKS IN THE POSTMENOPAUSAL WOMEN. ADDITIONALLY, YOGA TRAINING PROMOTED BETTER QUALITY OF LIFE.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
7  968 34 EFFECTS OF AN 8-MONTH ASHTANGA-BASED YOGA INTERVENTION ON BONE METABOLISM IN MIDDLE-AGED PREMENOPAUSAL WOMEN: A RANDOMIZED CONTROLLED STUDY. ALTHOUGH YOGA HAS THE POTENTIAL TO BE AN ALTERNATIVE PHYSICAL ACTIVITY TO ENHANCE BONE HEALTH, THERE IS A LACK OF HIGH QUALITY EVIDENCE FOR THIS TYPE OF INTERVENTION. THE PURPOSE OF THIS RANDOMIZED CONTROLLED TRIAL WAS TO EXAMINE THE EFFECTS OF A PROGRESSIVE 8-MONTH ASHTANGA-BASED YOGA PROGRAM ON BONE TURNOVER MARKERS (BTM), AREAL BONE MINERAL DENSITY (ABMD) AND VOLUMETRIC BONE CHARACTERISTICS IN PREMENOPAUSAL WOMEN. THIRTY-FOUR PREMENOPAUSAL WOMEN (35-50 YEARS) WERE RANDOMLY ASSIGNED EITHER TO A YOGA GROUP (YE, N = 16) OR A CONTROL GROUP (CON, N = 18). PARTICIPANTS IN YE GROUP PERFORMED 60 MINUTES OF AN ASHTANGA-BASED YOGA SERIES 2 TIMES/WEEK WITH ONE DAY BETWEEN SESSIONS FOR 8 MONTHS, AND THE SESSION INTENSITY WAS PROGRESSIVELY INCREASED BY ADDING THE NUMBER OF SUN SALUTATIONS (SS). PARTICIPANTS IN CON WERE ENCOURAGED TO MAINTAIN THEIR NORMAL DAILY LIFESTYLES MONITORED BY THE BONE SPECIFIC PHYSICAL ACTIVITY QUESTIONNAIRE (BPAQ) AT 2 MONTH INTERVALS FOR 8 MONTHS. BODY COMPOSITION WAS MEASURED BY DUAL ENERGY X-RAY ABSORPTIOMETRY (DXA). BONE FORMATION (BONE ALKALINE PHOSPHATASE, BONE ALP) AND BONE RESORPTION (TARTRATE-RESISTANT ACID PHOSPHATASE-5B, TRAP5B) MARKERS WERE ASSESSED AT BASELINE AND AFTER 8 MONTHS. ABMD OF TOTAL BODY, LUMBAR SPINE AND DUAL PROXIMAL FEMUR AND TIBIA BONE CHARACTERISTICS WERE MEASURED USING DXA AND PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY (PQCT), RESPECTIVELY. WE FOUND THAT THE SERUM BONE ALP CONCENTRATIONS WERE MAINTAINED IN YE, BUT SIGNIFICANTLY (P = 0.005) DECREASED IN CON AFTER THE 8 MONTH INTERVENTION, AND THERE WERE SIGNIFICANT (P = 0.002) GROUP DIFFERENCES IN BONE ALP PERCENT CHANGES (YE 9.1 +/- 4.0% VS. CON -7.1 +/- 2.3%). NO CHANGES IN TRAP5B WERE FOUND IN EITHER GROUP. THE 8-MONTH YOGA PROGRAM DID NOT INCREASE ABMD OR TIBIA BONE STRENGTH VARIABLES. BODY COMPOSITION RESULTS SHOWED NO CHANGES IN WEIGHT, FAT MASS, OR % FAT, BUT SMALL SIGNIFICANT INCREASES IN BONE FREE LEAN BODY MASS OCCURRED IN BOTH GROUPS. THE FINDINGS OF THIS STUDY SUGGEST THAT REGULAR LONG-TERM ASHTANGA YOGA HAD A SMALL POSITIVE EFFECT ON BONE FORMATION BUT DID NOT ALTER ABMD OR TIBIA BONE CHARACTERISTICS IN PREMENOPAUSAL WOMEN. KEY POINTSREGULAR LONG-TERM ASHTANGA-BASED YOGA PROGRAM HAD A SMALL POSITIVE EFFECT ON BONE FORMATION, BUT NO EFFECTS WERE FOUND ON BONE RESORPTION.NONE OF THE BONE DENSITY OR GEOMETRY VARIABLES WERE CHANGED BY THE 8-MONTH ASHTANGA-BASED YOGA INTERVENTION.FUTURE YOGA INTERVENTIONS SHOULD FOCUS ON LONGER DURATION AND GREATER FREQUENCY TO ELICIT IMPROVEMENTS IN BONE MINERAL DENSITY.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
8 2722 20 YOGA MIGHT BE AN ALTERNATIVE TRAINING FOR THE QUALITY OF LIFE AND BALANCE IN POSTMENOPAUSAL OSTEOPOROSIS. AIM: OSTEOPOROTIC VERTEBRA AND HIP FRACTURES ARE MAJOR CAUSES OF DYSFUNCTION, DISABILITY, MORTALITY AND IMPAIRED LIFE QUALITY IN THE AGEING POPULATION. IN THE POSTMENOPAUSAL PERIOD, EXERCISES PREVENT RAPID BONE LOSS AND INCREASE MUSCLE STRENGTH, MOBILITY AND FLEXIBILITY THEREBY DECREASING THE RISK OF FALLS AND FRACTURES. YOGA EXERCISES, WHICH HAVE BEEN AN INSEPARABLE PART OF EASTERN CULTURE FOR HUNDREDS OF YEARS, ARE NOW BEING USED IN THE FIELD OF OSTEOPOROSIS REHABILITATION. YOGA HAS A POSITIVE EFFECT ON BALANCE, POSTURE, FLEXIBILITY, AND LIFE QUALITY RESULTING FROM ITS EFFECTS ON BALANCE, STRETCHING, RELAXATION AND STRENGTHENING. THE AIM OF THIS STUDY WAS TO EVALUATE THE EFFECT OF YOGA EXERCISES IN POSTMENOPAUSAL OSTEOPOROTIC WOMEN ON BALANCE AND LIFE QUALITY AND TO COMPARE THE RESULTS WITH A CLASSIC OSTEOPOROSIS EXERCISE PROGRAM. METHODS: TWENTY-SIX POSTMENOPAUSAL OSTEOPOROTIC WOMEN OVER 55 YEARS OF AGE WERE INCLUDED IN THE STUDY. A NEUROMUSCULAR TEST BATTERY AND THE QUALEFFO AS A LIFE QUALITY INDEX WERE USED FOR THE ASSESSMENT OF BALANCE AND LIFE QUALITY, RESPECTIVELY. RESULTS: THE RESULTS SHOWED THAT YOGA EDUCATION HAS A POSITIVE EFFECT ON PAIN, PHYSICAL FUNCTIONS, SOCIAL FUNCTIONS, GENERAL CONCLUSION: IN CONCLUSION, YOGA APPEARS TO BE AN ALTERNATIVE PHYSICAL ACTIVITY FOR THE REHABILITATION OF OSTEOPOROTIC SUBJECTS.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
9 2853 23 YOGA, VERTEBRAL FRACTURES, AND OSTEOPOROSIS: RESEARCH AND RECOMMENDATIONS. BACKGROUND: OSTEOPOROSIS IS CHARACTERIZED BY DECREASED BONE DENSITY THAT LEAVES BONES FRAGILE AND HIGHLY SUSCEPTIBLE TO FRACTURE. GLOBALLY, 1 IN 3 WOMEN AND 1 IN 5 MEN OLDER THAN 50 WILL SUFFER FROM AN OSTEOPOROTIC FRACTURE, AND THOSE INDIVIDUALS WILL EXPERIENCE A CONSIDERABLY HIGHER RISK OF POSTFRACTURE MORTALITY THAN WILL THE GENERAL POPULATION. GENTLE, WEIGHT-BEARING EXERCISES SUCH AS YOGA CAN HELP PREVENT OR CEASE THE PROGRESSION OF OSTEOPOROSIS; HOWEVER, THERE IS INSUFFICIENT DATA REGARDING WHICH YOGA POSES PRESENT THE LEAST RISK AND ARE MOST BENEFICIAL TO INDIVIDUALS WITH REDUCED BONE DENSITY. OBJECTIVES: REVIEW THE EXTANT LITERATURE ABOUT THE RISKS AND BENEFITS TO THE SPINE OF PARTICULAR FORMS OF MOVEMENT AND CONSIDER RECOMMENDATIONS RELATIVE TO THE PRACTICE OF YOGA. METHODS: A REVIEW OF THE PUBMED, MEDLINE, AND COCHRANE DATABASES WAS CONDUCTED THAT IDENTIFIED MANUSCRIPTS PUBLISHED BETWEEN 1966 AND 2011 ABOUT TOPICS RELATED TO OSTEOPOROSIS AND SPINAL MOVEMENT. CONCLUSIONS: MOVEMENTS INVOLVING SPINAL FLEXION CAN INCREASE RISK FOR VERTEBRAL COMPRESSION FRACTURES; HOWEVER, A COMBINATION OF MILD SPINAL FLEXION AND EXTENSION MAY PROVE BENEFICIAL. MODERATE, WEIGHT-BEARING ACTIVITIES THAT STRENGTHEN THE MUSCLES SUPPORTING THE SPINAL COLUMN, PROMOTE BALANCE, IMPROVE POSTURE, AND ENHANCE QUALITY OF LIFE APPEAR TO BE OF GREATEST BENEFIT. AMPLE EVIDENCE SUPPORTS THE IMPORTANCE OF VARIED SPINAL MOVEMENT FOR PRESERVING THE HEALTH AND STRENGTH OF THE VERTEBRAL BODIES. EXERCISE MODIFICATIONS SUITABLE FOR HIGH-RISK INDIVIDUALS MAY BE COUNTERPRODUCTIVE FOR THOSE AT LOW RISK FOR VERTEBRAL FRACTURES. YOGA THERAPISTS ARE CAUTIONED TO NOT APPLY A ONE-SIZE-FITS-ALL APPROACH WHEN WORKING WITH THIS POPULATION. WELL-DESIGNED EMPIRICAL STUDIES ARE NEEDED TO FURTHER OUR UNDERSTANDING OF WHICH YOGA POSES PRESENT THE LEAST RISK AND ARE OF GREATEST BENEFIT TO INDIVIDUALS WITH OSTEOPOROSIS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
10 2393 12 YOGA AND BONE HEALTH. OSTEOPOROSIS IS A PUBLIC HEALTH PROBLEM AFFECTING INDIVIDUALS GLOBALLY. YOGA HAS BEEN FOUND TO PREVENT AND REVERSE BONE LOSS. YOGA MAY RESULT IN BETTER BALANCE, IMPROVED POSTURE, AND GREATER RANGE OF MOTION, STRENGTH, AND COORDINATION, ALL FACTORS THAT ALSO MITIGATE THE RISK OF FALLS AND FRACTURES. A 12-MINUTE, 12-POSE YOGA REGIMEN IS DISCUSSED IN DETAIL. ONCE LEARNED, THE ONGOING USE OF YOGA IS SAFE, WITHOUT COST, AND MAY BE DONE LIFELONG.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
11 2599 22 YOGA FOR OSTEOARTHRITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. PURPOSE OF REVIEW: THIS STUDY AIMS TO SYSTEMATICALLY REVIEW AND SUMMARISE THE EFFICACY AND SAFETY OF YOGA FOR OSTEOARTHRITIS. MEDLINE (THROUGH PUBMED), SCOPUS, AND THE COCHRANE LIBRARY WERE SEARCHED THROUGH APRIL 2018 FOR RANDOMISED CONTROLLED TRIALS OF YOGA FOR OSTEOARTHRITIS. PRIMARY OUTCOMES WERE PAIN INTENSITY, FUNCTION, AND QUALITY OF LIFE; SECONDARY OUTCOMES WERE MENTAL HEALTH AND SAFETY. RISK OF BIAS WAS ASSESSED USING THE COCHRANE TOOL AND QUALITY OF EVIDENCE THROUGH GRADE. RECENT FINDINGS: NINE TRIALS INCLUDING 640 INDIVIDUALS WITH MAINLY LOWER EXTREMITY OSTEOARTHRITIS AGED 50-80 YEARS WERE IDENTIFIED, WITH 80.3% FEMALE PARTICIPANTS (MEDIAN). META-ANALYSES REVEALED VERY LOW-QUALITY EVIDENCE FOR THE EFFECTS OF YOGA ON PAIN (VS. EXERCISE: STANDARDISED MEAN DIFFERENCE (SMD) = - 1.07; 95%CI - 1.92, - 0.21; P = 0.01; VS. NON-EXERCISE: SMD = - 0.75; 95%CI - 1.18, - 0.31; P < 0.001), PHYSICAL FUNCTION (VS. EXERCISE: SMD = 0.80; 95%CI 0.36; 1.24; P < 0.001; VS. NON-EXERCISE: SMD = 0.60; 95%CI 0.30, 0.98; P < 0.001), AND STIFFNESS (VS. EXERCISE: SMD = - 0.92; 95%CI - 1.69, - 0.14; P = 0.008; VS. NON-EXERCISE: SMD = - 0.76; 95%CI - 1.26, - 0.26; P = 0.003) IN INDIVIDUALS WITH KNEE OSTEOARTHRITIS. EFFECTS WERE NOT ROBUST AGAINST POTENTIAL METHODOLOGICAL BIAS. NO EFFECTS WERE FOUND FOR QUALITY OF LIFE, AND DEPRESSION, OR FOR HAND OSTEOARTHRITIS. SAFETY WAS RARELY REPORTED. THE FINDINGS OF THIS META-ANALYSIS INDICATE THAT YOGA MAY BE EFFECTIVE FOR IMPROVING PAIN, FUNCTION, AND STIFFNESS IN INDIVIDUALS WITH OSTEOARTHRITIS OF THE KNEE, COMPARED TO EXERCISE AND NON-EXERCISE CONTROL GROUPS. DUE TO THE LOW METHODOLOGICAL QUALITY AND POTENTIAL RISK OF BIAS, ONLY A WEAK RECOMMENDATION CAN BE MADE AT THIS TIME FOR THE USE OF YOGA IN ADULTS WITH OSTEOARTHRITIS OF THE KNEE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
12  404 19 BIKRAM YOGA TRAINING AND PHYSICAL FITNESS IN HEALTHY YOUNG ADULTS. THERE HAS BEEN RELATIVELY LITTLE LONGITUDINAL CONTROLLED INVESTIGATION OF THE EFFECTS OF YOGA ON GENERAL PHYSICAL FITNESS, DESPITE THE WIDESPREAD PARTICIPATION IN THIS FORM OF EXERCISE. THE PURPOSE OF THIS EXPLORATORY STUDY WAS TO EXAMINE THE EFFECT OF SHORT-TERM BIKRAM YOGA TRAINING ON GENERAL PHYSICAL FITNESS. YOUNG HEALTHY ADULTS WERE RANDOMIZED TO YOGA TRAINING (N = 10, 29 +/- 6 YEARS, 24 SESSIONS IN 8 WEEKS) OR A CONTROL GROUP (N = 11, 26 +/- 7 YEARS). EACH YOGA TRAINING SESSION CONSISTED OF 90-MINUTE STANDARDIZED SUPERVISED POSTURES PERFORMED IN A HEATED AND HUMIDIFIED STUDIO. ISOMETRIC DEADLIFT STRENGTH, HANDGRIP STRENGTH, LOWER BACK/HAMSTRING AND SHOULDER FLEXIBILITY, RESTING HEART RATE AND BLOOD PRESSURE, MAXIMAL OXYGEN CONSUMPTION (TREADMILL), AND LEAN AND FAT MASS (DUAL-ENERGY X-RAY ABSORPTIOMETRY) WERE MEASURED BEFORE AND AFTER TRAINING. YOGA SUBJECTS EXHIBITED INCREASED DEADLIFT STRENGTH, SUBSTANTIALLY INCREASED LOWER BACK/HAMSTRING FLEXIBILITY, INCREASED SHOULDER FLEXIBILITY, AND MODESTLY DECREASED BODY FAT COMPARED WITH CONTROL GROUP. THERE WERE NO CHANGES IN HANDGRIP STRENGTH, CARDIOVASCULAR MEASURES, OR MAXIMAL AEROBIC FITNESS. IN SUMMARY, THIS SHORT-TERM YOGA TRAINING PROTOCOL PRODUCED BENEFICIAL CHANGES IN MUSCULOSKELETAL FITNESS THAT WERE SPECIFIC TO THE TRAINING STIMULUS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
13  825 18 EFFECT OF YOGA ON HEALTH-RELATED OUTCOMES IN PEOPLE AT RISK OF FRACTURES: A SYSTEMATIC REVIEW. WE SUMMARIZED THE EFFECTS OF YOGA ON HEALTH-RELATED OUTCOMES AND ADVERSE EVENTS IN MEN AND POSTMENOPAUSAL WOMEN >/=50 YEARS-OLD AT INCREASED RISK OF FRACTURE, TO INFORM THE UPDATED OSTEOPOROSIS CANADA CLINICAL PRACTICE GUIDELINES. SIX DATABASES WERE SEARCHED FOR OBSERVATIONAL STUDIES, RANDOMIZED CONTROLLED TRIALS AND CASE SERIES. CERTAINTY OF EVIDENCE WAS ASSESSED USING THE GRADING OF RECOMMENDATIONS, ASSESSMENT, DEVELOPMENT AND EVALUATION HANDBOOK. NINE STUDIES WERE INCLUDED AND REPORTED USING NARRATIVE SYNTHESES DUE TO THE LIMITED AVAILABLE EVIDENCE. OVERALL, THE AVAILABLE EVIDENCE WAS OF VERY LOW CERTAINTY. THERE WAS NO EFFECT OF YOGA ON HEALTH-RELATED QUALITY OF LIFE IN RANDOMIZED TRIALS. EFFECTS ON OTHER HEALTH-RELATED OUTCOMES WERE MIXED OR NOT AVAILABLE IN THE LITERATURE. FIVE STUDIES REPORTED NO ADVERSE EVENTS DIRECTLY RELATED TO THE STUDY INTERVENTION, AND 2 STUDIES DID NOT REPORT WHETHER ADVERSE EVENTS OCCURRED. HOWEVER, 2 CASE SERIES REPORTED VERTEBRAL FRACTURES RELATED TO YOGA PARTICIPATION, POSSIBLY DUE TO EXCESSIVE SPINAL FLEXION. DUE TO THE LIMITED AND VERY LOW CERTAINTY EVIDENCE, GUIDELINE DEVELOPERS WILL NEED TO DRAW INDIRECT EVIDENCE FROM YOGA STUDIES AMONG MIDDLE AGED OR OLDER ADULTS THAT ARE NOT AT FRACTURE RISK. PROSPERO: CRD42019124898. NOVELTY: EVIDENCE IN GENERAL WAS OF VERY LOW CERTAINTY. YOGA HAD NO EFFECT ON HEALTH-RELATED QUALITY OF LIFE IN RANDOMIZED TRIALS. EVIDENCE WAS MIXED OR UNAVAILABLE FOR OTHER OUTCOMES. CASE STUDIES REPORTED YOGA POSES INVOLVING SPINAL FLEXION COINCIDED WITH INCIDENTS OF VERTEBRAL COMPRESSION FRACTURE AMONG OLDER ADULTS WITH INCREASED FRACTURE RISK.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
14 1623 24 MINDFULNESS AND MODIFIED MEDICAL YOGA AS INTERVENTION IN OLDER WOMEN WITH OSTEOPOROTIC VERTEBRAL FRACTURE. BACKGROUND: PEOPLE WITH OSTEOPOROTIC VERTEBRAL COMPRESSION FRACTURES (VCFS) HAVE DECREASED HEALTH-RELATED QUALITY OF LIFE (HRQOL). YOGA AND MINDFULNESS ARE METHODS THAT CAN PROMOTE WELL-BEING. OBJECTIVE: THE AIM OF THIS ARTICLE WAS TO EXPLORE THE EFFECT OF MINDFULNESS AND MODIFIED MEDICAL YOGA ON HRQOL, STRESS, SLEEP, AND PAIN IN PEOPLE 60 YEARS OR OLDER WITH A DIAGNOSED OSTEOPOROTIC VCF. DESIGN: THE SCHOOL OF OSTEOPOROSIS IN LINKOPING (SOL) IS A PILOT STUDY WITH RANDOMIZED GROUPS. MATERIALS AND METHODS: THE SOL-STUDY WAS SCHEDULED TO ONCE A WEEK FOR 10 WEEKS. TEN PEOPLE WERE RANDOMIZED TO A THEORY (T) GROUP, AND TEN PEOPLE WERE RANDOMIZED TO A THEORY AND MINDFULNESS/MEDICAL YOGA (MMY) GROUP. THE EDUCATIONAL SESSIONS LASTED 60 MIN AND WERE SIMILAR FOR THE GROUPS, BUT THEY TOOK PLACE AT DIFFERENT FACILITIES. AN EXPERIENCED PHYSIOTHERAPIST SUPERVISED THE MMY SESSIONS FOR 60 MIN. SLEEP QUALITY AND PRESENT STRESS EXPERIENCE WERE MEASURED ON A SYMMETRIC LIKERT SCALE. THE NUMERIC RATING SCALE WAS USED FOR PAIN, AND EQ-5D, RAND-36, AND QUALEFFO-41 WERE USED FOR HRQOL. THE PATIENT ENABLEMENT INSTRUMENT (PEI) WAS USED TO REFLECT HOW THE PARTICIPANTS COPED WITH THEIR ILLNESS. RESULTS: EIGHT WOMEN IN THE MMY-GROUP AND SEVEN WOMEN IN THE T-GROUP COMPLETED THE SOL STUDY INTERVENTIONS. THE ADHERENCE TO THE INTERVENTION PROGRAM WAS 89% IN THE MMY-GROUP AND 87% IN THE T-GROUP. THERE WAS NO ADVERSE CONSEQUENCE OF THE MMY TRAINING. AFTER THE 10-WEEK INTERVENTION PERIOD, SLEEP QUALITY (P = 0.018) AND PRESENT STRESS (P = 0.043), BUT NOT PERCEIVED PAIN WERE IMPROVED IN THE MMY-GROUP. THE SOCIAL FUNCTION (SF) DOMAIN WAS IMPROVED IN THE MMY-GROUP THAT WAS MEASURED BY BOTH RAND-36 (P = 0.028) AND QUALEFFO-41 (P = 0.012). THERE WAS A TREND TOWARD A BETTER PEI-SCORE IN THE MMY-GROUP COMPARED WITH THE T-GROUP POSTINTERVENTION (P = 0.089). CONCLUSION: THIS ARTICLE SUGGESTS THAT MINDFULNESS AND MODIFIED MEDICAL YOGA SUPERVISED BY A SKILLED PHYSIOTHERAPIST MAY BE A FEASIBLE WAY TO IMPROVE SF, SLEEP, AND STRESS IN OLDER WOMEN WITH OSTEOPOROTIC VCFS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
15  834 21 EFFECT OF YOGA ON OXIDATIVE STRESS IN TYPE 2 DIABETES MELLITUS: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: DIABETES MELLITUS HAS A SIGNIFICANT IMPACT ON PUBLIC HEALTH. OXIDATIVE STRESS PLAYS A MAJOR ROLE IN THE PATHOPHYSIOLOGY OF TYPE 2 DIABETES MELLITUS (T2DM), LEADING TO VARIOUS COMPLICATIONS OF T2DM. YOGA IS BEING WIDELY USED IN THE MANAGEMENT OF T2DM. THE PRIMARY OBJECTIVE OF THIS SYSTEMATIC REVIEW AND META-ANALYSIS IS TO UNDERSTAND THE EFFECTS OF YOGA ON OXIDATIVE STRESS PARAMETERS AMONG ADULT PATIENTS DIAGNOSED WITH T2DM. MATERIALS AND METHODS: ELECTRONIC DATABASES SUCH AS PUBMED, SCOPUS, COCHRANE LIBRARY AND SCIENCE DIRECT FROM START OF THE STUDY TILL MARCH 2020 WERE SEARCHED TO OBTAIN ELIGIBLE STUDIES. STUDY DESIGNS OF ALL NATURE WERE INCLUDED (EXCEPT CASE STUDIES AND REVIEWS). THE PRIMARY OUTCOME WAS MALONDIALDEHYDE (MDA) AND SECONDARY OUTCOMES INCLUDED FASTING PLASMA GLUCOSE, HBA1C AND SUPEROXIDE DISMUTASE (SOD) LEVELS. RESULTS: A TOTAL OF FOUR TRIALS WITH A TOTAL OF 440 PATIENTS MET THE INCLUSION CRITERIA. THE RESULTS OF META-ANALYSIS INDICATED THAT YOGA SIGNIFICANTLY REDUCED MDA (SMD: -1.4; 95% CI -2.66 TO -0.13; P = 0.03; I2 = 97%), FASTING PLASMA GLUCOSE LEVELS (SMD: -1.87: 95% CI -3.83 TO -0.09; P = 0.06; I2= 99%), AND HBA1C (SMD: -1.92; 95% CI - 3.03 TO -0.81; P = 0.0007; I2 = 92%) IN PATIENTS WITH T2DM. NO SUCH EFFECT WAS FOUND FOR SOD (SMD: -1.01; 95% CI -4.41 TO 2.38; P = 0.56; I2= 99%). CONCLUSION: THE AVAILABLE EVIDENCE SUGGESTS THAT YOGA REDUCES MDA, FASTING PLASMA GLUCOSE AND HBA1C, AND THUS WOULD BE BENEFICIAL IN THE MANAGEMENT OF T2DM AS A COMPLEMENTARY THERAPY. HOWEVER, CONSIDERING THE LIMITED NUMBER OF STUDIES AND ITS HETEROGENEITY, FURTHER ROBUST STUDIES ARE NECESSARY TO STRENGTHEN OUR FINDINGS AND INVESTIGATE THE LONG-TERM BENEFITS OF YOGA.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
16 2128 28 THE EFFECTIVENESS OF YOGA IN MODIFYING RISK FACTORS FOR CARDIOVASCULAR DISEASE AND METABOLIC SYNDROME: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: YOGA, A POPULAR MIND-BODY PRACTICE, MAY PRODUCE CHANGES IN CARDIOVASCULAR DISEASE (CVD) AND METABOLIC SYNDROME RISK FACTORS. DESIGN: THIS WAS A SYSTEMATIC REVIEW AND RANDOM-EFFECTS META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS (RCTS). METHODS: ELECTRONIC SEARCHES OF MEDLINE, EMBASE, CINAHL, PSYCINFO, AND THE COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS WERE PERFORMED FOR SYSTEMATIC REVIEWS AND RCTS THROUGH DECEMBER 2013. STUDIES WERE INCLUDED IF THEY WERE ENGLISH, PEER-REVIEWED, FOCUSED ON ASANA-BASED YOGA IN ADULTS, AND REPORTED RELEVANT OUTCOMES. TWO REVIEWERS INDEPENDENTLY SELECTED ARTICLES AND ASSESSED QUALITY USING COCHRANE'S RISK OF BIAS TOOL. RESULTS: OUT OF 1404 RECORDS, 37 RCTS WERE INCLUDED IN THE SYSTEMATIC REVIEW AND 32 IN THE META-ANALYSIS. COMPARED TO NON-EXERCISE CONTROLS, YOGA SHOWED SIGNIFICANT IMPROVEMENT FOR BODY MASS INDEX (-0.77 KG/M(2) (95% CONFIDENCE INTERVAL -1.09 TO -0.44)), SYSTOLIC BLOOD PRESSURE (-5.21 MMHG (-8.01 TO -2.42)), LOW-DENSITY LIPOPROTEIN CHOLESTEROL (-12.14 MG/DL (-21.80 TO -2.48)), AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL (3.20 MG/DL (1.86 TO 4.54)). SIGNIFICANT CHANGES WERE SEEN IN BODY WEIGHT (-2.32 KG (-4.33 TO -0.37)), DIASTOLIC BLOOD PRESSURE (-4.98 MMHG (-7.17 TO -2.80)), TOTAL CHOLESTEROL (-18.48 MG/DL (-29.16 TO -7.80)), TRIGLYCERIDES (-25.89 MG/DL (-36.19 TO -15.60), AND HEART RATE (-5.27 BEATS/MIN (-9.55 TO -1.00)), BUT NOT FASTING BLOOD GLUCOSE (-5.91 MG/DL (-16.32 TO 4.50)) NOR GLYCOSYLATED HEMOGLOBIN (-0.06% HB (-0.24 TO 0.11)). NO SIGNIFICANT DIFFERENCE WAS FOUND BETWEEN YOGA AND EXERCISE. ONE STUDY FOUND AN IMPACT ON SMOKING ABSTINENCE. CONCLUSIONS: THERE IS PROMISING EVIDENCE OF YOGA ON IMPROVING CARDIO-METABOLIC HEALTH. FINDINGS ARE LIMITED BY SMALL TRIAL SAMPLE SIZES, HETEROGENEITY, AND MODERATE QUALITY OF RCTS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
17 2118 22 THE EFFECT OF YOGA PRACTICE ON GLYCEMIC CONTROL AND OTHER HEALTH PARAMETERS IN THE PREDIABETIC STATE: A SYSTEMATIC REVIEW AND META-ANALYSIS. A SYSTEMATIC REVIEW AND META-ANALYSIS WAS CONDUCTED TO INVESTIGATE THE EFFECTS OF YOGA ON GLYCEMIC CONTROL, LIPID PROFILES, BODY COMPOSITION AND BLOOD PRESSURE IN PEOPLE IN THE PRE-DIABETIC STATE. STUDIES ON THE EFFECTIVENESS OF YOGA ON POPULATION GROUPS UNDER HIGH RISK FOR DIABETES, CALLED PREDIABETIC OR SUFFERING FROM METABOLIC SYNDROMES WERE EXTRACTED FROM A THOROUGH SEARCH OF PUBMED, SCOPUS, COCHRANE LIBRARY, EBSCO AND INDMED DATABASES. BOTH RANDOMISED CONTROLLED TRIAL (RCT) AND NON-RCT STUDIES WERE INCLUDED IN THE SYSTEMATIC REVIEW AND META-ANALYSIS. STUDIES PUBLISHED BETWEEN JAN 2002 AND DEC 2018 WERE INCLUDED. STUDIES WERE CONSIDERED FOR EVALUATION IF THEY INVESTIGATED A YOGA INTERVENTION TO PREVENT T2DM, AGAINST A CONTROL GROUP, WHILE ALSO REPORTING GLYCEMIC CONTROL AND OTHER HEALTH PARAMETERS OF T2DM MANAGEMENT. SUMMARY EFFECT SIZES AND 95% CONFIDENCE INTERVALS (CI) WERE CALCULATED USING THE COMPREHENSIVE META-ANALYSIS SOFTWARE IN ADDITION TO PUBLICATION BIAS. OF THE 46,500 IDENTIFIED STUDIES, 14 STUDIES WITH 834 PARTICIPANTS OF WHOM WERE 50% WOMEN, WERE FOUND TO BE ELIGIBLE FOR INCLUSION IN OUR SYSTEMATIC REVIEW. OUR QUANTITATIVE SYNTHESIS INCLUDED 12 RANDOMIZED CONTROL TRIALS AND 2 NON-RANDOMIZED CONTROL TRIALS, WITH THE FOLLOW-UP PERIOD RANGING FROM 4 TO 52 WEEKS. COMPARED TO CONTROLS, YOGA INTERVENTION IMPROVED FASTING BLOOD GLUCOSE (FBG) [STANDARD MEAN DIFFERENCE (SMD -0.064 MG/DL (95% CI -0.201 TO 0.074)]; LOW DENSITY LIPOPROTEIN (LDL) [SMD-0.090 MG/DL (95% CI -0.270 TO 0.090)]; TRIGLYCERIDES [SMD -0.148 MG/DL (95% CI -0.285 TO -0.012)]; TOTAL CHOLESTEROL [SMD -0.058 MG/DL (95% CI -0.220 TO 0.104)] AND SYSTOLIC BLOOD PRESSURE [SMD -0.058 MM HG (95% CI -0.168 TO 0.053)]. THIS META-ANALYSIS UNCOVERED CLINICALLY IMPROVED EFFECTS OF YOGA INTERVENTION ON GLYCEMIC CONTROL, LIPID PROFILES AND OTHER PARAMETERS OF T2DM MANAGEMENT IN PREDIABETIC POPULATION. THESE RESULTS SUGGEST THAT YOGA INTERVENTION MAY BE CONSIDERED AS A COMPREHENSIVE AND ALTERNATIVE APPROACH TO PREVENTING T2DM. FURTHER ADEQUATELY POWERED, WELL DESIGNED RCTS ARE NEEDED TO SUPPORT OUR FINDINGS AND INVESTIGATE THE LONG-TERM EFFECTS OF YOGA IN T2DM PATIENTS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
18 1116 17 EFFICACY OF A VALIDATED YOGA PROTOCOL ON DYSLIPIDEMIA IN DIABETES PATIENTS: NMB-2017 INDIA TRIAL. BACKGROUND: DYSLIPIDEMIA IS CONSIDERED A RISK FACTOR IN TYPE 2 DIABETES MELLITUS (T2DM) RESULTING IN CARDIO-VASCULAR COMPLICATIONS. YOGA PRACTICES HAVE SHOWN PROMISING RESULTS IN ALLEVIATING TYPE 2 DIABETES PATHOLOGY. METHOD: IN THIS STRATIFIED TRIAL ON A YOGA BASED LIFESTYLE PROGRAM IN CASES WITH TYPE 2 DIABETES, IN THE RURAL AND URBAN POPULATION FROM ALL ZONES OF INDIA, A TOTAL OF 17,012 ADULTS (>20 YEARS) OF BOTH GENDERS WERE SCREENED FOR LIPID PROFILE AND SUGAR LEVELS. THOSE WHO SATISFIED THE SELECTION CRITERIA WERE TAUGHT THE DIABETES YOGA PROTOCOL (DYP) FOR THREE MONTHS AND THE DATA WERE ANALYZED. RESULTS: AMONG THOSE WITH DIABETES, 29.1% HAD ELEVATED TOTAL CHOLESTEROL (TC > 200 MG/DL) LEVELS THAT WERE HIGHER IN URBAN (69%) THAN RURAL (31%) DIABETES PATIENTS. THERE WAS A POSITIVE CORRELATION (P = 0.048) BETWEEN HBA1C AND TOTAL CHOLESTEROL LEVELS. DYP INTERVENTION HELPED IN REDUCING TC FROM 232.34 +/- 31.48 MG/DL TO 189.38 +/- 40.23 MG/DL WITH SIGNIFICANT PRE POST DIFFERENCE (P < 0.001). CONVERSION RATE FROM HIGH TC (>200 MG/DL) TO NORMAL TC (<200 MG/DL) WAS OBSERVED IN 60.3% OF CASES WITH TYPE 2 DIABETES MELLITUS (T2DM); FROM HIGH LDL (>130 MG/DL) TO NORMAL LDL (<130 MG/DL) IN 73.7%; FROM HIGH TRIGLYCERIDE (>200 MG/DL) TO NORMAL TRIGLYCERIDE LEVEL (<200 MG/DL) IN 63%; FROM LOW HDL (<45 MG/DL) TO NORMAL HDL (>45 MG/DL) IN 43.7% OF T2DM PATIENTS AFTER THREE MONTHS OF DYP. CONCLUSIONS: A YOGA LIFESTYLE PROGRAM DESIGNED SPECIFICALLY TO MANAGE DIABETES HELPS IN REDUCING THE CO-MORBIDITY OF DYSLIPIDEMIA IN CASES OF PATIENTS WITH T2DM.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
19 2518 35 YOGA COMPARED TO NON-EXERCISE OR PHYSICAL THERAPY EXERCISE ON PAIN, DISABILITY, AND QUALITY OF LIFE FOR PATIENTS WITH CHRONIC LOW BACK PAIN: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: CHRONIC LOW BACK PAIN (CLBP) IS A COMMON AND OFTEN DISABLING MUSCULOSKELETAL CONDITION. YOGA HAS BEEN PROVEN TO BE AN EFFECTIVE THERAPY FOR CHRONIC LOW BACK PAIN. HOWEVER, THERE ARE STILL CONTROVERSIES ABOUT THE EFFECTS OF YOGA AT DIFFERENT FOLLOW-UP PERIODS AND COMPARED WITH OTHER PHYSICAL THERAPY EXERCISES. OBJECTIVE: TO CRITICALLY COMPARE THE EFFECTS OF YOGA FOR PATIENTS WITH CHRONIC LOW BACK PAIN ON PAIN, DISABILITY, QUALITY OF LIFE WITH NON-EXERCISE (E.G. USUAL CARE, EDUCATION), PHYSICAL THERAPY EXERCISE. METHODS: THIS STUDY WAS REGISTERED IN PROSPERO, AND THE REGISTRATION NUMBER WAS CRD42020159865. RANDOMIZED CONTROLLED TRIALS (RCTS) OF ONLINE DATABASES INCLUDED PUBMED, WEB OF SCIENCE, COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS, EMBASE WHICH EVALUATED EFFECTS OF YOGA FOR PATIENTS WITH CHRONIC LOW BACK PAIN ON PAIN, DISABILITY, AND QUALITY OF LIFE WERE SEARCHED FROM INCEPTION TIME TO NOVEMBER 1, 2019. STUDIES WERE ELIGIBLE IF THEY ASSESSED AT LEAST ONE IMPORTANT OUTCOME, NAMELY PAIN, BACK-SPECIFIC DISABILITY, QUALITY OF LIFE. THE COCHRANE RISK OF BIAS TOOL WAS USED TO ASSESS THE METHODOLOGICAL QUALITY OF INCLUDED RANDOMIZED CONTROLLED TRIALS. THE CONTINUOUS OUTCOMES WERE ANALYZED BY CALCULATING THE MEAN DIFFERENCE (MD) OR STANDARDIZED MEAN DIFFERENCE (SMD) WITH 95% CONFIDENCE INTERVALS (CI) ACCORDING TO WHETHER COMBINING OUTCOMES MEASURED ON DIFFERENT SCALES OR NOT. RESULTS: A TOTAL OF 18 RANDOMIZED CONTROLLED TRIALS WERE INCLUDED IN THIS META-ANALYSIS. YOGA COULD SIGNIFICANTLY REDUCE PAIN AT 4 TO 8 WEEKS (MD = -0.83, 95% CI = -1.19 TO -0.48, P<0.00001, I2 = 0%), 3 MONTHS (MD = -0.43, 95% CI = -0.64 TO -0.23, P<0.0001, I2 = 0%), 6 TO 7 MONTHS (MD = -0.56, 95% CI = -1.02 TO -0.11, P = 0.02, I2 = 50%), AND WAS NOT SIGNIFICANT IN 12 MONTHS (MD = -0.52, 95% CI = -1.64 TO 0.59, P = 0.36, I2 = 87%) COMPARED WITH NON-EXERCISE. YOGA WAS BETTER THAN NON-EXERCISE ON DISABILITY AT 4 TO 8 WEEKS (SMD = -0.30, 95% CI = -0.51 TO -0.10, P = 0.003, I2 = 0%), 3 MONTHS (SMD = -0.31, 95% CI = -0.45 TO -0.18, P<0.00001, I2 = 30%), 6 MONTHS (SMD = -0.38, 95% CI = -0.53 TO -0.23, P<0.00001, I2 = 0%), 12 MONTHS (SMD = -0.33, 95% CI = -0.54 TO -0.12, P = 0.002, I2 = 9%). THERE WAS NO SIGNIFICANT DIFFERENCE ON PAIN, DISABILITY COMPARED WITH PHYSICAL THERAPY EXERCISE GROUP. FURTHERMORE, IT SUGGESTED THAT THERE WAS A NON-SIGNIFICANT DIFFERENCE ON PHYSICAL AND MENTAL QUALITY OF LIFE BETWEEN YOGA AND ANY OTHER INTERVENTIONS. CONCLUSION: THIS META-ANALYSIS PROVIDED EVIDENCE FROM VERY LOW TO MODERATE INVESTIGATING THE EFFECTIVENESS OF YOGA FOR CHRONIC LOW BACK PAIN PATIENTS AT DIFFERENT TIME POINTS. YOGA MIGHT DECREASE PAIN FROM SHORT TERM TO INTERMEDIATE TERM AND IMPROVE FUNCTIONAL DISABILITY STATUS FROM SHORT TERM TO LONG TERM COMPARED WITH NON-EXERCISE (E.G. USUAL CARE, EDUCATION). YOGA HAD THE SAME EFFECT ON PAIN AND DISABILITY AS ANY OTHER EXERCISE OR PHYSICAL THERAPY. YOGA MIGHT NOT IMPROVE THE PHYSICAL AND MENTAL QUALITY OF LIFE BASED ON THE RESULT OF A MERGING.	2020	

20 2607 25 YOGA FOR PRENATAL DEPRESSION: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: PRENATAL DEPRESSION CAN NEGATIVELY AFFECT THE PHYSICAL AND MENTAL HEALTH OF BOTH MOTHER AND FETUS. THE AIM OF THIS STUDY WAS TO DETERMINE THE EFFECTIVENESS OF YOGA AS AN INTERVENTION IN THE MANAGEMENT OF PRENATAL DEPRESSION. METHODS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS (RCTS) WAS CONDUCTED BY SEARCHING PUBMED, EMBASE, THE COCHRANE LIBRARY AND PSYCINFO FROM ALL RETRIEVED ARTICLES DESCRIBING SUCH TRIALS UP TO JULY 2014. RESULTS: SIX RCTS WERE IDENTIFIED IN THE SYSTEMATIC SEARCH. THE SAMPLE CONSISTED OF 375 PREGNANT WOMEN, MOST OF WHOM WERE BETWEEN 20 AND 40 YEARS OF AGE. THE DIAGNOSES OF DEPRESSION WERE DETERMINED BY THEIR SCORES ON STRUCTURED CLINICAL INTERVIEW FOR DSM-IV AND THE CENTER FOR EPIDEMIOLOGICAL STUDIES DEPRESSION SCALE. WHEN COMPARED WITH COMPARISON GROUPS (E.G., STANDARD PRENATAL CARE, STANDARD ANTENATAL EXERCISES, SOCIAL SUPPORT, ETC.), THE LEVEL OF DEPRESSION STATISTICALLY SIGNIFICANTLY REDUCED IN YOGA GROUPS (STANDARDIZED MEAN DIFFERENCE [SMD], -0.59; 95% CONFIDENCE INTERVAL [CI], -0.94 TO -0.25; P = 0.0007). ONE SUBGROUP ANALYSIS REVEALED THAT BOTH THE LEVELS OF DEPRESSIVE SYMPTOMS IN PRENATALLY DEPRESSED WOMEN (SMD, -0.46; CI, -0.90 TO -0.03; P = 0.04) AND NON-DEPRESSED WOMEN (SMD, -0.87; CI, -1.22 TO -0.52; P < 0.00001) WERE STATISTICALLY SIGNIFICANTLY LOWER IN YOGA GROUP THAN THAT IN CONTROL GROUP. THERE WERE TWO KINDS OF YOGA: THE PHYSICAL-EXERCISE-BASED YOGA AND INTEGRATED YOGA, WHICH, BESIDES PHYSICAL EXERCISES, INCLUDED PRANAYAMA, MEDITATION OR DEEP RELAXATION. THEREFORE, THE OTHER SUBGROUP ANALYSIS WAS CONDUCTED TO ESTIMATE EFFECTS OF THE TWO KINDS OF YOGA ON PRENATAL DEPRESSION. THE RESULTS SHOWED THAT THE LEVEL OF DEPRESSION WAS SIGNIFICANTLY DECREASED IN THE INTEGRATED YOGA GROUP (SMD, -0.79; CI, -1.07 TO -0.51; P < 0.00001) BUT NOT SIGNIFICANTLY REDUCED IN PHYSICAL-EXERCISE-BASED YOGA GROUP (SMD, -0.41; CI, -1.01 TO -0.18; P = 0.17). CONCLUSIONS: PRENATAL YOGA INTERVENTION IN PREGNANT WOMEN MAY BE EFFECTIVE IN PARTLY REDUCING DEPRESSIVE SYMPTOMS.	2015