1 1296 130 GUINNESS WORLD RECORD ATTEMPT AS A METHOD TO PIVOT THE ROLE OF YOGA IN DIABETES MANAGEMENT. BACKGROUND: ATTEMPTS FOR GUINNESS WORLD RECORD HAVE CONTINUED WORLDWIDE BUT THESE ATTEMPTS WERE RARELY AIMED TO PROMOTE PUBLIC HEALTH. DIABETES IS ONE OF THE RAPIDLY GROWING LIFESTYLE DISORDERS IN INDIA WHICH REQUIRES AWARENESS REINFORCEMENTS AMONG THE LOCAL POPULATION. IN RECENT STUDIES, YOGA HAS PROVED TO BE USEFUL IN LIFESTYLE MODIFICATION AND DIABETES MANAGEMENT. HOWEVER, MOST INDIVIDUALS FROM RURAL AND URBAN LOCALITIES IN THE COUNTRY ARE UNAWARE OF THIS FACT. PURPOSE: THE PURPOSE WAS TO ORGANIZING A NATIONWIDE ATTEMPT UNDER THE NIYANTRIT MADHUMEH BHARAT (NMB) PROGRAMME TO BREAK THE WORLD RECORD TO BE THE LARGEST DIABETES LESSON, TO SPREAD AWARENESS AMONG GENERAL POPULATION. METHODS: PRESENT ARTICLE REPRESENTS THE PERSPECTIVE OF THE CHANDIGARH CHAPTER OF NMB PROGRAMME AND ITS EXPERIENCE IN GUINNESS WORLD RECORD ATTEMPT. DIABETES AWARENESS LESSON WAS ORGANIZED IN THE CITY AS PER THE STANDARDS DEFINED BY THE GUINNESS BOOK AND OUTCOMES OF THE ENTIRE CAMPAIGN WERE ASSESSED AT THE END OF THE CAMPAIGN. RESULT: TOTAL 498 INDIVIDUALS PARTICIPATED IN THE CAMPAIGN. AMONG THEM, 268 PARTICIPANTS WERE QUESTIONED AT THE END OF THE CAMPAIGN ABOUT THE ROLE OF YOGA IN DIABETES. 247 PARTICIPANTS (92%) WERE AGREED THAT DIABETES CAN BE MODIFIED BY YOGA AND 9 PARTICIPANTS (3%) DISAGREED. THE REMAINING 12 PARTICIPANTS (5%) DID NOT GIVE ANY RESPONSE. CONCLUSION: WE NOTICED THAT MOST OF THE PARTICIPANTS BECAME AWARE OF THE ROLE OF YOGA IN DIABETES.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
2 1540  44 KNOWLEDGE, ATTITUDE, AND PRACTICE OF YOGA IN RURAL AND URBAN INDIA, KAPY 2017: A NATIONWIDE CLUSTER SAMPLE SURVEY. : BACKGROUND: TO EXAMINE THE KNOWLEDGE, ATTITUDES, AND PRACTICE GAP OF YOGA ACROSS INDIA BASED ON IMPLICIT PERCEPTIONS. METHODS: THE PRESENT STUDY IS A NATIONWIDE DOOR-TO-DOOR SURVEY CONDUCTED USING A QUESTIONNAIRE/SCREENING FORM. THE DATA WERE COLLECTED FROM A NATIONAL SURVEY CONDUCTED UNDER THE NIYANTRIT MADHUMEH BHARAT (NMB) PROGRAM INITIATED BY THE MINISTRY OF AYURVEDA, YOGA, UNANI, SIDDHA, HOMEOPATHY (AYUSH), GOVERNMENT OF INDIA, FROM ALL MAJOR ZONES OF THE COUNTRY. A TOTAL OF 162,330 PARTICIPANTS WHO JOINED THE NMB PROGRAM WERE RECRUITED IN OUR STUDY. RESULTS: OUT OF THE TOTAL RESPONDENTS TO THE SURVEY, IT WAS OBSERVED THAT 11.8% [13,336/112,735] PRACTICE YOGA, WHICH WAS HIGHEST IN THE NORTH ZONE [4,567/112,735] AND LOWEST IN THE EAST ZONE [971/112,735]. OUT OF 101,643 RESPONDENTS, 94,135 OF THE INDIVIDUALS WHO PARTICIPATED IN THE SURVEY BELIEVED THAT YOGA IMPROVED THEIR LIFESTYLE, AND 90,102/98,518 BELIEVED THAT YOGA PREVENTED DIABETES, REVEALING A HUGE KNOWLEDGE-PRACTICE GAP. CONCLUSIONS: THE SCALE OF THE KNOWLEDGE-PRACTICE GAP COUPLED WITH THE GENERAL ACCEPTABILITY OF YOGA CALLS FOR A CHANGE IN THE CONVENTIONAL HEALTHCARE PROVISIONS BY ITS INTEGRATION WITH MODERN MEDICINE. THE POPULATION-WIDE POSITIVE PERCEPTIONS ABOUT YOGA AS A PREVENTIVE HEALTH TOOL CAN NOT ONLY CATALYZE CONSENSUS DISEASE-SPECIFIC YOGA MODULES BUT ALSO BRIDGE THE KNOWLEDGE-PRACTICE GAP THAT EXISTS BECAUSE OF LIMITED YOGA CENTERS AND PROFESSIONALS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
3  921  41 EFFECTIVENESS OF YOGA AS THE PUBLIC HEALTH INTERVENTION MODULE IN THE MANAGEMENT OF DIABETES AND DIABETES ASSOCIATED DEMENTIA IN SOUTH EAST ASIA: A NARRATIVE REVIEW. BACKGROUND: DIABETES MELLITUS (DM) IS WIDELY SPREAD IN SOUTH ASIAN (ASEAN) AND INDIAN SUB-CONTINENT. THE INCREASING HEALTHCARE COSTS OF DM CAN BE PREVENTED IN THE DEVELOPING WORLD BY IMPROVED PUBLIC HEALTHCARE INTERVENTIONS. MODIFIABLE RISK FACTORS OF DM LIKE SEDENTARY LIFESTYLE, OBESITY, AND STRESSFUL CONDITIONS ARE ASSOCIATED WITH ITS PROGRESSION; HOWEVER, THE EPIDEMIOLOGICAL DATA COLLECTED BY PUBLIC INSTITUTIONS ARE LIMITED. SUMMARY: A REVIEW OF PUBLISHED LITERATURE DESCRIBING GEOGRAPHIC DISTRIBUTION OF DM AND ASSOCIATED DEMENTIA IN SOUTH ASIAN REGION, PARTICULARLY INDIA, WAS CONDUCTED WITH THE PURPOSE OF ASSESSING THE FEASIBILITY AND CHALLENGES ASSOCIATED WITH THE YOGA-BASED RISK REDUCTION. PUBMED AND GOOGLE SCHOLAR DATABASES WERE SEARCHED FOR DM AND DEMENTIA-RELATED ARTICLES BY USING A COMBINATION OF KEYWORDS: DIABETES, DIABETES RELATED DEMENTIA SOUTHEAST ASIA, PRE-DIABETES, YOGA, LIFESTYLE MODIFICATION, DEMENTIA AND EXERCISE. THE EPIDEMIOLOGICAL DATA GENERATED FROM THESE DISEASES HAVE NOT PROMPTED TO ANY MAJOR PUBLIC HEALTH POLICIES. YOGA CAN BE A COST-EFFECTIVE INTERVENTION FOR THE PREVENTION OF TYPE 2 DM (T2DM) AND ITS ASSOCIATED COGNITIVE DECLINE WHEN DETECTED EARLY. IF NATIONWIDE INTERVENTION OF YOGA IS BROUGHT ABOUT BY THE STATE, ITS INTEGRATION IN HEALTH CARE WILL BECOME MORE MEANINGFUL AND ACCEPTABLE. KEY MESSAGE: STUDIES SUGGEST THAT YOGA AND CHANGE IN LIFESTYLE CAN MODIFY THE HEALTH RISKS ASSOCIATED WITH T2DM AND ASSOCIATED DEMENTIA IF IT IS MAINSTREAMED WITH THE PUBLIC HEALTH INITIATIVE OF AYUSHMAN BHARAT SCHEME.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
4  903  42 EFFECTIVENESS OF A YOGA-BASED LIFESTYLE PROTOCOL (YLP) IN PREVENTING DIABETES IN A HIGH-RISK INDIAN COHORT: A MULTICENTER CLUSTER-RANDOMIZED CONTROLLED TRIAL (NMB-TRIAL). INTRODUCTION: THOUGH SEVERAL LINES OF EVIDENCE SUPPORT THE UTILITY OF YOGA-BASED INTERVENTIONS IN DIABETES PREVENTION, MOST OF THESE STUDIES HAVE BEEN LIMITED BY METHODOLOGICAL ISSUES, PRIMARILY SAMPLE SIZE INADEQUACY. HENCE, WE TESTED THE EFFECTIVENESS OF YOGA-BASED LIFESTYLE INTERVENTION AGAINST DIABETES RISK REDUCTION IN MULTICENTRE, LARGE COMMUNITY SETTINGS OF INDIA, THROUGH A SINGLE-BLIND CLUSTER-RANDOMIZED CONTROLLED TRIAL, NIYANTRITA MADHUMEHA BHARAT ABHIYAN (NMB). RESEARCH DESIGN AND METHODS: NMB-TRIAL IS A MULTICENTRE CLUSTER-RANDOMIZED TRIAL CONDUCTED IN 80 CLUSTERS [COMPOSED OF RURAL UNITS (VILLAGES) AND URBAN UNITS (CENSUS ENUMERATION BLOCKS)] RANDOMLY ASSIGNED IN A 1:1 RATIO TO INTERVENTION AND CONTROL GROUPS. PARTICIPANTS WERE INDIVIDUALS (AGE, 20-70 YEARS) WITH PREDIABETES (BLOOD HBA1C VALUES IN THE RANGE OF 5.7-6.4%) AND IDRS >/= 60. THE INTERVENTION INCLUDED THE PRACTICE OF YOGA-BASED LIFESTYLE MODIFICATION PROTOCOL (YLP) FOR 9 CONSECUTIVE DAYS, FOLLOWED BY DAILY HOME AND WEEKLY SUPERVISED PRACTICES FOR 3 MONTHS. THE CONTROL CLUSTER RECEIVED STANDARD OF CARE ADVICE FOR DIABETES PREVENTION. STATISTICAL ANALYSES WERE PERFORMED ON AN INTENTION-TO-TREAT BASIS, USING AVAILABLE AND IMPUTED DATASETS. THE PRIMARY OUTCOME WAS THE CONVERSION FROM PREDIABETES TO DIABETES AFTER THE YLP INTERVENTION OF 3 MONTHS (DIAGNOSED BASED UPON HBA1C CUTOFF >6.5%). SECONDARY OUTCOME INCLUDED REGRESSION TO NORMOGLYCEMIA WITH HBA1C <5.7%. RESULTS: A TOTAL OF 3380 (75.96%) PARTICIPANTS WERE FOLLOWED UP AT 3 MONTHS. AT 3 MONTHS POST-INTERVENTION, OVERALL, DIABETES DEVELOPED IN 726 (21.44%) PARTICIPANTS. YLP WAS FOUND TO BE SIGNIFICANTLY EFFECTIVE IN HALTING PROGRESSION TO DIABETES AS COMPARED TO STANDARD OF CARE; ADJUSTED RRR WAS 63.81(95% CI = 56.55-69.85). THE YLP ALSO ACCELERATED REGRESSION TO NORMOGLYCEMIA [ADJUSTED ODDS RATIO (ADJOR) = 1.20 (95% CI, 1.02-1.43)]. IMPORTANTLY, YOUNGER PARTICIPANTS (</=40 YEARS) WERE FOUND TO REGRESS TO NORMOGLYCEMIA MORE EFFECTIVELY THAN THE OLDER PARTICIPANTS PINTERACTION<0.001. CONCLUSION: BASED ON THE SIGNIFICANT RISK REDUCTION DERIVED FROM THE LARGE SAMPLE SIZE, AND THE CAREFULLY DESIGNED RANDOMIZED YOGA-BASED INTERVENTION ON HIGH-RISK POPULATIONS, THE STUDY IS A PRELIMINARY BUT STRONG PROOF-OF-CONCEPT FOR YOGA AS A POTENTIAL LIFESTYLE-BASED TREATMENT TO CURB THE EPIDEMIC OF DIABETES. THE OBSERVED FINDINGS ALSO INDICATE A POTENTIAL OF YLP FOR DIABETES PREVENTION IN LOW/MODERATE RISK PROFILE INDIVIDUALS THAT NEEDS LARGE-SCALE VALIDATION. TRIAL REGISTRATION: CLINICAL TRIAL REGISTRATION NUMBER: CTRI/2018/03/012804.	2021	

5 1803  38 PREVALENCE OF DIABETES AND ITS DETERMINANTS IN THE YOUNG ADULTS INDIAN POPULATION-CALL FOR YOGA INTERVENTION. BACKGROUND: THE YOUNG INDIAN POPULATION, WHICH CONSTITUTES 65% OF THE COUNTRY, IS FAST ADAPTING TO A NEW LIFESTYLE, WHICH WAS NOT KNOWN EARLIER. THEY ARE AT A HIGH RISK OF THE INCREASING BURDEN OF DIABETES AND ASSOCIATED COMPLICATIONS. THE NEW EVOLVING LIFESTYLE IS NOT ONLY AFFECTING PEOPLE'S HEALTH BUT ALSO MOUNTING THE MONETARY BURDEN ON A DEVELOPING COUNTRY SUCH AS INDIA. AIM: WE AIMED TO COLLECT INFORMATION REGARDING THE PREVALENCE OF RISK OF DIABETES IN YOUNG ADULTS (<35 YEARS) IN THE 29 MOST POPULOUS STATES AND UNION TERRITORIES (7 ZONES) OF INDIA, USING A VALIDATED QUESTIONNAIRE. METHODS: A USER-FRIENDLY QUESTIONNAIRE-BASED SURVEY USING A MOBILE APPLICATION WAS CONDUCTED ON ALL ADULTS IN THE 29 MOST POPULOUS STATES/UNION TERRITORIES OF INDIA, AFTER OBTAINING ETHICAL CLEARANCE FOR THE STUDY. HERE, WE REPORT THE ESTIMATION OF THE PREVALENCE OF THE RISK OF DIABETES AND SELF-REPORTED DIABETES ON 58,821 YOUNG INDIVIDUALS BELOW THE AGE OF 35 YEARS. RISK FOR DIABETES WAS ASSESSED USING A STANDARDIZED INSTRUMENT, THE INDIAN DIABETES RISK SCORE (IDRS), THAT HAS 4 FACTORS (AGE, FAMILY HISTORY OF DIABETES, WAIST CIRCUMFERENCE, AND PHYSICAL ACTIVITY). SPEARMAN'S CORRELATION COEFFICIENT WAS USED TO CHECK THE CORRELATIONS. RESULTS: THE PREVALENCE OF HIGH (IDRS SCORE > 60), MODERATE (IDRS SCORE 30-50), AND LOW (IDRS < 30) DIABETES RISK IN YOUNG ADULTS (<35 YEARS) WAS 10.2%, 33.1%, AND 56.7%, RESPECTIVELY. THOSE WITH HIGH-RISK SCORES WERE HIGHEST (14.4%) IN THE JAMMU ZONE AND LOWEST (4.1%) IN THE CENTRAL ZONE. THE PREVALENCE OF SELF-REPORTED DIABETES WAS 1.8% WITH A SMALL DIFFERENCE BETWEEN MEN (1.7%) AND WOMEN (1.9%), AND THE HIGHEST (8.4%) IN THOSE WITH A PARENTAL HISTORY OF DIABETES. THE SOUTH ZONE HAD THE HIGHEST (2.5%), AND THE NORTH WEST ZONE HAD THE LOWEST (4.4%) PREVALENCE. CONCLUSIONS: INDIAN YOUTH ARE AT HIGH RISK FOR DIABETES, WHICH CALLS FOR AN URGENT ACTION PLAN THROUGH INTENSIVE EFFORTS TO PROMOTE LIFESTYLE BEHAVIOR MODIFICATIONS DURING THE PANDEMICS OF BOTH COMMUNICABLE AND NONCOMMUNICABLE DISEASES.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
6 1568  20 MAINSTREAMING OF AYURVEDA, YOGA, NATUROPATHY, UNANI, SIDDHA, AND HOMEOPATHY WITH THE HEALTH CARE DELIVERY SYSTEM IN INDIA. INDIA HAS A POPULATION OF 1.21 BILLION PEOPLE AND THERE IS A HIGH DEGREE OF SOCIO-CULTURAL, LINGUISTIC, AND DEMOGRAPHIC HETEROGENEITY. THERE IS A LIMITED NUMBER OF HEALTH CARE PROFESSIONALS, ESPECIALLY DOCTORS, PER HEAD OF POPULATION. THE NATIONAL RURAL HEALTH MISSION HAS DECIDED TO MAINSTREAM THE AYURVEDA, YOGA, NATUROPATHY, UNANI, SIDDHA, AND HOMEOPATHY (AYUSH) SYSTEM OF INDIGENOUS MEDICINE TO HELP MEET THE CHALLENGE OF THIS SHORTAGE OF HEALTH CARE PROFESSIONALS AND TO STRENGTHEN THE DELIVERY SYSTEM OF THE HEALTH CARE SERVICE. MULTIPLE INTERVENTIONS HAVE BEEN IMPLEMENTED TO ENSURE A SYSTEMATIC MERGER; HOWEVER, THE ANTICIPATED RESULTS HAVE NOT BEEN ACHIEVED AS A RESULT OF MULTIPLE CHALLENGES AND BARRIERS. TO ENSURE THE ACCESSIBILITY AND AVAILABILITY OF HEALTH CARE SERVICES TO ALL, POLICY-MAKERS NEED TO IMPLEMENT STRATEGIES TO FACILITATE THE MAINSTREAMING OF THE AYUSH SYSTEM AND TO SUPPORT THIS SYSTEM WITH STRINGENT MONITORING MECHANISMS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
7  625  30 DIABETIC YOGA PROTOCOL IMPROVES GLYCEMIC, ANTHROPOMETRIC AND LIPID LEVELS IN HIGH RISK INDIVIDUALS FOR DIABETES: A RANDOMIZED CONTROLLED TRIAL FROM NORTHERN INDIA. PURPOSE: TO STUDY THE EFFECTIVENESS OF DIABETIC YOGA PROTOCOL (DYP) AGAINST MANAGEMENT OF CARDIOVASCULAR RISK PROFILE IN A HIGH-RISK COMMUNITY FOR DIABETES, FROM CHANDIGARH, INDIA. METHODS: THE STUDY WAS A RANDOMIZED CONTROLLED TRIAL, CONDUCTED AS A SUB STUDY OF THE PAN INDIA TRIAL NIYANTRITA MADHUMEHA BHARATH (NMB). THE COHORT WAS IDENTIFIED THROUGH THE INDIAN DIABETES RISK SCORING (IDRS) (>/= 60) AND A TOTAL OF 184 INDIVIDUALS WERE RANDOMIZED INTO INTERVENTION (N = 91) AND CONTROL GROUPS (N = 93). THE DYP GROUP UNDERWENT THE SPECIFIC DYP TRAINING WHEREAS THE CONTROL GROUP FOLLOWED THEIR DAILY REGIMEN. THE STUDY OUTCOMES INCLUDED CHANGES IN GLYCEMIC AND LIPID PROFILE. ANALYSIS WAS DONE UNDER INTENT-TO-TREAT PRINCIPLE. RESULTS: THE 3 MONTHS DYP PRACTICE SHOWED DIVERSE RESULTS SHOWING GLYCEMIC AND LIPID PROFILE OF THE HIGH RISK INDIVIDUALS. THREE MONTHS OF DYP INTERVENTION WAS FOUND TO SIGNIFICANTLY REDUCE THE LEVELS OF POST-PRANDIAL GLUCOSE LEVELS (P = 0.035) AND LDL-C LEVELS (P = 0.014) AND WAIST CIRCUMFERENCE (P = 0.001). CONCLUSION: THE FINDINGS INDICATE THAT THE DYP INTERVENTION COULD IMPROVE THE METABOLIC STATUS OF THE HIGH-DIABETES-RISK INDIVIDUALS WITH RESPECT TO THEIR GLUCOSE TOLERANCE AND LIPID LEVELS, PARTIALLY EXPLAINED BY THE REDUCTION IN ABDOMINAL OBESITY. THE STUDY HIGHLIGHTS THE POTENTIAL ROLE OF YOGA INTERVENTION IN REAL TIME IMPROVEMENT OF CARDIOVASCULAR PROFILE IN A HIGH DIABETES RISK COHORT. TRIAL REGISTRATION: CTRI, CTRI/2018/03/012804. REGISTERED 01 MARCH 2018-RETROSPECTIVELY REGISTERED, HTTP://WWW.CTRI.NIC.IN/ CTRI/2018/03/012804.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
8 1911  26 ROLE OF AYURVEDA AND YOGA-BASED LIFESTYLE IN THE COVID-19 PANDEMIC - A NARRATIVE REVIEW. THE COVID-19 PANDEMIC HAS POSED AN IMMENSE CHALLENGE TO HEALTH CARE SYSTEMS AROUND THE GLOBE IN TERMS OF LIMITED HEALTH CARE FACILITIES AND PROVEN MEDICAL THERAPEUTICS TO ADDRESS THE SYMPTOMS OF THE INFECTION. THE CURRENT HEALTH CARE STRATEGIES ARE PRIMARILY FOCUSED ON EITHER THE PATHOGEN OR THE ENVIRONMENTAL FACTORS. HOWEVER, EFFORTS TOWARDS STRENGTHENING THE HOST IMMUNITY ARE IMPORTANT FROM PUBLIC HEALTH PERSPECTIVE TO PREVENT THE SPREAD OF INFECTION AND DOWNREGULATE THE POTENCY OF THE INFECTIOUS AGENT. WHILE A VACCINE CAN INDUCE SPECIFIC IMMUNITY IN THE HOST, NON-SPECIFIC WAYS OF IMPROVING OVERALL HOST IMMUNITY ARE NEEDED AS WELL. THIS SCENARIO HAS PAVED THE WAY FOR THE USE OF TRADITIONAL INDIAN THERAPIES SUCH AS AYURVEDA AND YOGA. THIS REVIEW AIMS AT COLLATING AVAILABLE EVIDENCE ON AYURVEDA, YOGA, AND COVID-19. FURTHER, IT DRAWS INFERENCES FROM RECENT STUDIES ON YOGA AND AYURVEDA ON IMMUNITY, RESPIRATORY HEALTH, AND MENTAL HEALTH RESPECTIVELY TO APPROXIMATE ITS PROBABLE ROLE IN PROPHYLAXIS AND AS AN ADD-ON MANAGEMENT OPTION FOR THE CURRENT PANDEMIC.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
9 2130  28 THE EFFECTIVENESS OF YOGA TO PREVENT DIABETES MELLITUS TYPE 2: A PROTOCOL FOR SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: TYPE 2 DIABETES MELLITUS (T2DM) IS BECOMING A LEADING PROBLEM WORLDWIDE. EMERGING REPORTS REVEAL ALARMING EVIDENCE OF INCREASING PREVALENCE OF T2DM THAT HAS REACHED PANDEMIC LEVELS. DESPITE THE SIGNIFICANT INCIDENCE, THERE ARE LIMITED RELIABLE DATA RESOURCES AND COMPREHENSIVE SYSTEMATIC REVIEW AND META-ANALYSIS ON THE EFFECTS OF YOGA ON PEOPLE WHO ARE A PREDIABETIC OR HIGH RISK FOR DEVELOPING T2DM. OBJECTIVE: THE OBJECTIVE OF THIS PROTOCOL IS TO CONDUCT A FULL-SCALE SYSTEMATIC REVIEW AND META-ANALYSES ON THE EFFECTS OF YOGA ON PEOPLE WHO ARE PREDIABETES OR HIGH RISK OF DEVELOPING T2DM. METHODS: THE ARTICLES ENROLLED IN THE STUDY WILL BE RETRIEVED FROM THE ONLINE DATABASES BETWEEN 2002 AND THE DATE THE SEARCHES ARE EXECUTED. THE SEARCHES WILL BE REPEATED JUST BEFORE THE FINAL ANALYSES AND FURTHER RELEVANT STUDIES FOR INCLUSION. WE WILL CONDUCT A BIBLIOGRAPHIC SEARCH IN DATABASES: MEDLINE/PUBMED, SCOPUS, COCHRANE LIBRARY, EBSCO, AND INDMED USING KEYWORDS INCLUDING PREDIABETES STATE, HIGH RISK FOR DIABETES, METABOLIC SYNDROME, AND YOGA. A DEFINED SEARCH STRATEGY WILL BE IMPLEMENTED ALONG WITH SELECTION CRITERIA TO OBTAIN FULL-TEXT ARTICLES OF RELEVANT STUDIES. THIS STUDY PROTOCOL WAS PREPARED ACCORDING TO THE PREFERRED REPORTING ITEMS FOR SYSTEMATIC REVIEWS AND META-ANALYSIS FOR PROTOCOLS 2015 GUIDELINES. THERE WILL BE NO LANGUAGE RESTRICTIONS. ETHICS AND DISSEMINATION: THE PROPOSED STUDY WILL BE BASED ON PUBLISHED STUDIES AND PUBLICLY AVAILABLE ANONYMIZED DATA WITHOUT DIRECTLY INVOLVING HUMAN PARTICIPANTS AND THEREFORE REQUIRES NEITHER FORMAL HUMAN ETHICAL REVIEW NOR APPROVAL BY A HUMAN RESEARCH ETHICS COMMITTEE. WE PUBLISHED AN OUTLINE OF THE PROTOCOL IN THE INTERNATIONAL PROSPECTIVE REGISTER OF SYSTEMATIC REVIEWS (PROSPERO) IN 2018. WE PLAN TO DISSEMINATE THE FINDINGS OF THIS SYSTEMATIC REVIEW AND META-ANALYSIS THROUGH PUBLICATION IN A PEER-REVIEWED JOURNAL AND PRESENTATION AT RELEVANT CONFERENCE PROCEEDINGS. IN ADDITION, WE BELIEVE THE RESULTS OF THE SYSTEMATIC REVIEW WILL HAVE IMPLICATIONS FOR POLICY AND PRACTICE. WE WILL PREPARE POLICYMAKER SUMMARY USING A VALIDATED FORMAT, DISSEMINATE THROUGH SOCIAL MEDIA AND EMAIL DISCUSSION GROUPS. REVIEW REGISTRATION NUMBER: PROSPERO REGISTRATION NUMBER CRD 42018106657.	2019	
                                                                                                                                                                                                                                                                                                                                                                                             
10 2057  21 THE BENEFITS OF YOGA FOR ADULTS WITH TYPE 2 DIABETES: A REVIEW OF THE EVIDENCE AND CALL FOR A COLLABORATIVE, INTEGRATED RESEARCH INITIATIVE. TYPE 2 DIABETES (T2DM) IS A GLOBAL PUBLIC HEALTH CRISIS. RESEARCH SUGGESTS THAT YOGA HOLDS PROMISE FOR T2DM MANAGEMENT. THIS ARTICLE SUMMARIZES EVIDENCE REGARDING THE EFFICACY OF YOGA FOR T2DM MANAGEMENT AND ENCOURAGES THE DEVELOPMENT OF AN INTEGRATED RESEARCH AGENDA AND A COLLABORATIVE WORK GROUP TO TEST IT. WE PRESENT A BRIEF OVERVIEW OF THE GLOBAL RISE IN T2DM AND ITS CONSEQUENCES AND COSTS, REVIEW THE EVIDENCE REGARDING THE POTENTIAL BENEFITS OF YOGA FOR T2DM MANAGEMENT, OUTLINE LIMITATIONS IN THE LITERATURE, DISCUSS POSSIBLE MECHANISMS UNDERLYING THE EFFECTS OF YOGA ON T2DM, AND SUGGEST HOW A COLLABORATIVE, MULTINATIONAL EFFORT BY YOGA THERAPIST AND RESEARCH COMMUNITIES MIGHT CONTRIBUTE TO RESEARCH AND INFORM CLINICAL PRACTICE. YOGA PROTOCOLS THAT SERVE T2DM PATIENTS AND A RESEARCH FRAMEWORK FOR CREATING AN EVIDENCE BASE TO SUPPORT THE USE OF YOGA FOR T2DM MANAGEMENT ARE CLEARLY NEEDED.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
11 2416  25 YOGA AND MEDITATION IN CARDIOVASCULAR DISEASE. YOGA IS A HOLISTIC MIND-BODY INTERVENTION AIMED AT PHYSICAL, MENTAL, EMOTIONAL AND SPIRITUAL WELL BEING. SEVERAL STUDIES HAVE SHOWN THAT YOGA AND/OR MEDITATION CAN CONTROL RISK FACTORS FOR CARDIOVASCULAR DISEASE LIKE HYPERTENSION, TYPE II DIABETES AND INSULIN RESISTANCE, OBESITY, LIPID PROFILE, PSYCHOSOCIAL STRESS AND SMOKING. SOME RANDOMIZED STUDIES SUGGEST THAT YOGA/MEDITATION COULD RETARD OR EVEN REGRESS EARLY AND ADVANCED CORONARY ATHEROSCLEROSIS. A RECENT STUDY SUGGESTS THAT TRANSCENDENTAL MEDITATION MAY BE EXTREMELY USEFUL IN SECONDARY PREVENTION OF CORONARY HEART DISEASE AND MAY REDUCE CARDIOVASCULAR EVENTS BY 48% OVER A 5-YEAR PERIOD. ANOTHER SMALL STUDY SUGGESTS THAT YOGA MAY BE HELPFUL IN PREVENTION OF ATRIAL FIBRILLATION. HOWEVER, MOST STUDIES HAVE SEVERAL LIMITATIONS LIKE LACK OF ADEQUATE CONTROLS, SMALL SAMPLE SIZE, INCONSISTENCIES IN BASELINE AND DIFFERENT METHODOLOGIES, ETC. AND THEREFORE LARGE TRIALS WITH IMPROVED METHODOLOGIES ARE REQUIRED TO CONFIRM THESE FINDINGS. HOWEVER, IN VIEW OF THE EXISTING KNOWLEDGE AND YOGA BEING A COST-EFFECTIVE TECHNIQUE WITHOUT SIDE EFFECTS, IT APPEARS APPROPRIATE TO INCORPORATE YOGA/MEDITATION FOR PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASE.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
12 2013  23 SUDARSHAN KRIYA YOGA: A BREATH OF HOPE DURING COVID-19 PANDEMIC. IMPORTANT COUNTER MEASURES TO COMBAT AN INFECTIOUS DISEASE PANDEMIC INCLUDE VACCINATION, ANTIVIRAL THERAPY, AND IMMUNOMODULATION THERAPY. VACCINATIONS ARE DISEASE SPECIFIC AND MOREOVER STRAIN SPECIFIC, SO THE PROTECTION PROVIDED IS ALSO SPECIFIC AND LIMITED. ANTIVIRAL THERAPIES ARE COSTLY AND REQUIRE BULK PRODUCTION OF DRUGS, HENCE GLOBALLY THERE IS AN INCREASED INTEREST TOWARD LOW-RISK, COST-EFFECTIVE COMPLEMENTARY ALTERNATIVE THERAPIES, SUCH AS YOGA AND AYURVEDA TO TACKLE THE INFECTIOUS PANDEMIC, CORONAVIRUS DISEASE 2019 (COVID-19). THERE IS CLINICAL EVIDENCE AVAILABLE ON THE POTENTIAL COMPLEMENTARY ROLE OF YOGIC PRACTICES IN THE MANAGEMENT OF NONCOMMUNICABLE AND COMMUNICABLE DISEASES. VARIOUS ONLINE DATABASES WERE SEARCHED FOR ARTICLES PUBLISHED BETWEEN 2000 AND 2020. DATABASES EXPLORED WERE MEDLINE, EMBASE, INDIAN CITATION INDEX, PSYCINFO, INDEX MEDICUS FOR SOUTH-EAST ASIA REGION, AND GOOGLE SCHOLAR. ALL SEARCH RESULTS WERE SCREENED, AND ARTICLES RELATED TO KEYWORDS SUCH AS COVID-19, YOGA THERAPY, AND SUDARSHAN KRIYA YOGA (SKY) WERE SELECTED FOR DATA EXTRACTION. QUALITY OF THE STUDIES INCLUDED WAS EVALUATED ON THE BASIS OF THE CONSTRUCT VALIDITY, CONTENT VALIDITY, RELEVANCE, BIAS, CREDIBILITY RELATING TO INFORMATION, AND DATA SOURCES. SKY IS A UNIQUE YOGIC PRACTICE THAT INCLUDES SPECIFIC SEQUENTIAL BREATHING TECHNIQUES. IT BALANCES THE AUTONOMIC NERVOUS SYSTEM AND THUS CAN ALLEVIATE ANXIETY, ROUTINE STRESS, DEPRESSION, STRESS-RELATED MEDICAL DISORDERS, AND POSTTRAUMATIC STRESS. IT POTENTIATES NATURAL HOST IMMUNE DEFENSES THAT ARE ESSENTIAL TO TACKLE A PLETHORA OF MICROBIAL INFECTIONS. THIS NARRATIVE REVIEW ARTICLE PROVIDES AN OVERVIEW OF POTENTIAL THERAPEUTIC BENEFITS THAT SKY CAN OFFER TO THE POPULATION AT LARGE DURING THIS COVID-19 PANDEMIC.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
13  613  28 DEVELOPMENT OF A YOGA PROGRAM FOR TYPE-2 DIABETES PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA. INTRODUCTION: MANY INDIANS ARE AT HIGH-RISK OF TYPE-2 DIABETES MELLITUS (T2DM). YOGA IS AN ANCIENT INDIAN MIND-BODY DISCIPLINE, THAT HAS BEEN ASSOCIATED WITH IMPROVED GLUCOSE LEVELS AND CAN HELP TO PREVENT T2DM. THE STUDY AIMED TO SYSTEMATICALLY DEVELOP A YOGA PROGRAM FOR T2DM PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA USING A COMPLEX INTERVENTION DEVELOPMENT APPROACH. MATERIALS AND METHODS: AS PART OF THE INTERVENTION, WE DEVELOPED A BOOKLET AND A HIGH-DEFINITION VIDEO FOR PARTICIPANTS AND A MANUAL FOR YOGA-DP INSTRUCTORS. A SYSTEMATIC ITERATIVE PROCESS WAS FOLLOWED TO DEVELOP THE INTERVENTION AND INCLUDED FIVE STEPS: (I) A SYSTEMATIC REVIEW OF THE LITERATURE TO GENERATE A LIST OF YOGIC PRACTICES THAT IMPROVES BLOOD GLUCOSE LEVELS AMONG ADULTS AT HIGH-RISK OF OR WITH T2DM, (II) VALIDATION OF IDENTIFIED YOGIC PRACTICES BY YOGA EXPERTS, (III) DEVELOPMENT OF THE INTERVENTION, (IV) CONSULTATION WITH YOGA, EXERCISE, PHYSICAL ACTIVITY, DIET, BEHAVIOR CHANGE, AND/OR DIABETES EXPERTS ABOUT THE INTERVENTION, AND (V) PRETEST THE INTERVENTION AMONG YOGA PRACTITIONERS AND LAY PEOPLE (THOSE AT RISK OF T2DM AND HAD NOT PRACTICED YOGA BEFORE) IN INDIA. RESULTS: YOGA-DP IS A STRUCTURED LIFESTYLE EDUCATION AND EXERCISE PROGRAM, PROVIDED OVER A PERIOD OF 24 WEEKS. THE EXERCISE PART IS BASED ON YOGA AND INCLUDES SHITHILIKARANA VYAYAMA (LOOSENING EXERCISES), SURYA NAMASKAR (SUN SALUTATION EXERCISES), ASANA (YOGIC POSES), PRANAYAMA (BREATHING PRACTICES), AND DHYANA (MEDITATION) AND RELAXATION PRACTICES. ONCE PARTICIPANTS COMPLETE THE PROGRAM, THEY ARE STRONGLY ENCOURAGED TO MAINTAIN A HEALTHY LIFESTYLE IN THE LONG-TERM. CONCLUSIONS: WE SYSTEMATICALLY DEVELOPED A NOVEL YOGA PROGRAM FOR T2DM PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA. A MULTI-CENTER FEASIBILITY RANDOMIZED CONTROLLED TRIAL IS IN PROGRESS IN INDIA.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
14   94  28 A NARRATIVE REVIEW ON ROLE OF YOGA AS AN ADJUVANT IN THE MANAGEMENT OF RISK FACTOR, DISEASE PROGRESSION AND THE COMPLICATIONS OF TYPE 2 DIABETES MELLITUS. TYPE 2 DIABETES MELLITUS (T2DM) IS ONE OF THE MAJOR HEALTH PROBLEMS IN THE WORLD AS WELL AS IN INDIA THAT GREATLY AFFECTS THE HEALTH CARE SECTOR AND ECONOMY. USE OF DRUGS HAS ITS OWN DRAWBACKS AND IN RECENT DAYS THE USE OF NON-MEDICAL MEASURES WERE REPORTED NOT ONLY TO MANAGE T2DM, BUT ALSO TO PREVENT ITS COMPLICATIONS. THROUGH THERE ARE VARIOUS REVIEW ARTICLES THAT ARE DEALING WITH THE EFFECT OF YOGA ON RISK PROFILES, MANAGEMENT ALONG WITH THE MECHANISMS OF ACTION OF YOGA IN T2DM SEPARATELY, THERE IS A LACK OF COMPREHENSIVE REVIEW ON THE EFFECT OF YOGA IN COMBINATION WITH ALL THE ABOVE MENTIONED INCLUDING THE EFFECT OF YOGA IN THE MANAGEMENT OF T2DM COMPLICATIONS. HENCE, WE PERFORMED A NARRATIVE REVIEW IN MEDLINE/PUBMED USING KEYWORD "YOGA AND DIABETES". ALL THE RELEVANT ARTICLES PUBLISHED TILL 08TH NOVEMBER 2016 WERE INCLUDED. BASED ON THE AVAILABLE LITERATURE, IT COULD BE CONCLUDED THAT YOGA PLAYS A VITAL ROLE AS AN ADJUVANT IN THE MANAGEMENT OF RISK FACTORS, DISEASE PROGRESSION AND THE COMPLICATIONS OF THE T2DM. FURTHER STUDIES ARE WARRANTED USING STANDARD RESEARCH DESIGNS AND VARIABLES TO FIND OUT THE VARIOUS MECHANISMS OF EFFECTS OF YOGA IN DETAIL.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
15 2275  33 THE ROLE OF YOGA IN WORKING FROM HOME DURING THE COVID-19 GLOBAL LOCKDOWN. BACKGROUND: THE COVID-19 PANDEMIC HAS BECOME A MAJOR CAUSE OF STRESS AND ANXIETY WORLDWIDE. DUE TO THE GLOBAL LOCKDOWN, WORK, EMPLOYMENT, BUSINESSES AND THE ECONOMIC CLIMATE HAVE BEEN SEVERELY AFFECTED. IT HAS GENERATED STRESS AMONG PEOPLE FROM ALL SECTIONS OF SOCIETY, ESPECIALLY TO WORKERS WHO HAVE BEEN ASSIGNED TO CATER TO HEALTHCARE SERVICE OR THOSE CONSTRAINED TO SECURE DAILY ESSENTIAL ITEMS. IT IS WIDELY PERCEIVED THAT ELDERLY OR THOSE AFFECTED BY DIABETES, HYPERTENSION AND OTHER CARDIOVASCULAR DISEASES ARE PRONE TO COVID-19. AS PER AN ONGOING SURVEY, THE INITIAL DATA SHOWS THAT THE ABOVE-MENTIONED ANXIETY AND STRESS CAUSE INSOMNIA, AND HAS THE CONSIDERABLE POTENTIAL TO WEAKEN THE IMMUNE SYSTEM, THE SOLE PROTECTION AGAINST THE VIRUS. OBJECTIVE: THIS STUDY FOCUSES ON THE NEED OF YOGA PRACTICE AT WORK PLACES AND AT HOME DURING THE GLOBAL LOCKDOWN DUE TO THE COVID-19 PANDEMIC. METHODS: LITERATURE WAS SEARCHED USING PUBMED AND GOOGLE SCHOLAR FOR COVID-19-RELATED STRESS AND ANXIETY AT WORK AND SOCIETY DUE TO THE WORLDWIDE LOCKDOWN. THE PREDISPOSING COMORBIDITIES, VIRAL MECHANISM OF ACTION AND TREATMENT REGIMEN WERE ALSO SEARCHED. YOGA-BASED INTERVENTION STUDIES AND ONLINE PROGRAMS WERE ALSO SEARCHED. RESULTS: AS THE LOCKDOWN CANNOT LAST FOREVER AND WORKPLACES WILL HAVE TO BE FUNCTIONAL SOON, THERE IS AN INCREASED POSSIBILITY OF RECURRENT INFECTION. THEREFORE, YOGA CAN PROVIDE THE NECESSARY TOOL FOR RISK REDUCTION, AMELIORATION OF STRESS AND ANXIETY AND STRENGTHENING OF THE IMMUNE FUNCTION. THE ONLINE PLATFORMS PROVIDE A GOOD MEDIA FOR YOGA TRAINING AT WORK PLACES AND HOMES. CONCLUSION: DUE TO SOCIAL DISTANCING NORMS, THE AVAILABILITY OF YOGA TRAINERS HAS BECOME RESTRICTED. YOGA PRACTICE IS ACTIVELY SOUGHT TO ACHIEVE REDUCED ANXIETY AND STRESS SO THAT IMPROVED SLEEP MAY POSITIVELY IMPACT IMMUNITY. AS A CONSEQUENCE, THERE IS A SPURT IN SOCIAL MEDIA, CATERING TO DAILY ONLINE YOGA SESSIONS WHICH APPARENTLY PROVE USEFUL IN PROVIDING ACCESSIBLE MEANS TO ACHIEVE MENTAL AS WELL AS PHYSICAL WELL-BEING.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
16  103  35 A PILOT CROSS-SECTIONAL SURVEY ON AWARENESS AND PRACTICE REGARDING TYPE 2 DIABETES MELLITUS AND ITS MANAGEMENT WITH YOGA. DIABETES MELLITUS IS A METABOLIC DISORDER OF MULTIPLE ETIOLOGY, CHARACTERIZED BY CHRONIC HYPERGLYCAEMIA WITH DISTURBANCE OF CARBOHYDRATE, FAT, AND PROTEIN METABOLISM RESULTING FROM DEFECT IN INSULIN SECRETION, INSULIN ACTION OR BOTH. IMPROPER LIFESTYLE CONTRIBUTES TO THE INCREASING NUMBER OF PEOPLE AFFECTED WITH TYPE 2 DIABETES MELLITUS (T2DM). SYSTEMATIC REVIEWS ON THE MANAGEMENT OF T2DM IN ADULTS THROUGH YOGA REPORTED SIGNIFICANT IMPROVEMENTS IN MULTIPLE MODIFIABLE INDICES OF DIABETES MELLITUS MANAGEMENT INCLUDING GLYCEMIC CONTROL, LIPID LEVELS, AND BODY COMPOSITION. AWARENESS LEVELS OF A CONDITION AMONG THE POPULATION PLAY A CRITICAL ROLE IN BEHAVIOUR CHANGE. HOWEVER, STUDIES RELATED TO ASSESSING THE AWARENESS AND PRACTICE OF YOGA FOR MANAGING DISEASES ARE LIMITED. HENCE, THIS STUDY WAS FORMULATED WITH THE OBJECTIVE OF ASSESSING THE AWARENESS LEVEL AND EXTENT OF KNOWLEDGE ABOUT DIABETES MELLITUS AND ITS MANAGEMENT THROUGH YOGA. A CROSS-SECTIONAL SURVEY WITH A SAMPLE SIZE OF 317 WAS CONDUCTED USING A STRUCTURED QUESTIONNAIRE AT 5 DISTRICTS IN TAMIL NADU AND KERALA. 95% OF THE STUDY POPULATION WERE AWARE OF DIABETES MELLITUS WHILE 61.2% RESPONDED THAT DIABETES CAN BE PREVENTED BY REGULAR EXERCISE AND HEALTHY DIET. 62.4% PEOPLE PERCEIVED THAT YOGA PRACTICES CAN PREVENT DIABETES MELLITUS AND 59% MENTIONED THAT REGULAR YOGA PRACTICE CAN HELP IN CONTROLLING DIABETES AND PREVENT FURTHER COMPLICATIONS. ONLY 13% REPORTED TO PRACTICE YOGA REGULARLY AT LEAST THREE DAYS A WEEK. IDENTIFYING A QUALIFIED YOGA TRAINER WAS REPORTED TO BE A LIMITING FACTOR FOR REGULAR YOGA PRACTICE. THE STUDY SUGGESTED THAT THERE IS A NEED TO INCREASE THE ACCESS TO QUALIFIED YOGA PROFESSIONALS AT COMMUNITY LEVEL. FURTHER LARGE SCALE STUDIES WITH RANDOM SAMPLING METHOD TO ASSESS THE AWARENESS LEVEL AND PRACTICE OF YOGA IN DIFFERENT SETTINGS IS INDICATED.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
17 2882  16 YOGA: A THERAPEUTIC APPROACH. YOGA, PRACTICED WIDELY IN THE EAST, IS NOW POPULAR IN THE WEST AS PART OF A HEALTHY LIFESTYLE. THIS ARTICLE BRINGS A MEDICAL PERSPECTIVE TO THE PRACTICE OF YOGA. SELECTED YOGA POSTURES THAT ARE BELIEVED TO BENEFIT CERTAIN MEDICAL CONDITIONS ARE HIGHLIGHTED. IN ADDITION, THE PHILOSOPHY, GENERAL GUIDELINES, AND MEDICAL BENEFITS OF YOGA PRACTICE ARE DESCRIBED.	2004	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
18  140  25 A PROSPECTIVE STUDY ON TYPE-2 DIABETIC COMPLICATIONS AND EFFICACY OF INTEGRATED YOGA: A PAN INDIA 2017. BACKGROUND: TYPE 2 DIABETES (T2DM) CONTRIBUTES TO HIGH MORTALITY AND MORBIDITY BECAUSE OF ITS MAJOR COMPLICATIONS RELATED TO KIDNEY, HEART, BRAIN, AND EYES. IT ALSO POSES A HIGH RISK FOR MORTALITY BECAUSE OF COVID-19. STUDIES SUGGEST THE POSSIBLE IMPLICATIONS OF YOGA IN DELAYING OR ATTENUATING SUCH COMPLICATIONS. METHODOLOGY: THIS WAS A PAN-INDIA MULTI CENTERED CLUSTER-RANDOMIZED (4 LEVEL) TWO-ARMED TRIAL IN THE RURAL AND URBAN POPULATION OF ALL POPULOUS STATES OF INDIA. DATA WERE OBTAINED USING MOBILE APP IN ALL ADULTS IN THE HOUSEHOLD OF THE SELECTED CLUSTERS. RESULTS: WE REPORT THE DIABETES RELATED COMPLICATIONS IN 16623 ADULTS (48% MALES, 52% FEMALES) FROM 65 DISTRICTS (1 IN 10 DISTRICTS, 2011 CENSUS) OF 29 (OUT OF 35) STATES AND UNION TERRITORIES OF INDIA; MEAN AGE WAS 48.2 +/- 12.46 YEARS. OUT OF THIS 40% LIVED IN RURAL AND 62% IN URBAN LOCATIONS. IN HIGH RISK DIABETES INDIVIDUALS (SCORED >/= 60 POINTS ON INDIAN DIABETES RISK SCORE KEY), 18.0% HAD SELF-REPORTED HISTORY OF (PERIPHERAL NEUROPATHY, 6.1% HAD H/O MAJOR STROKES, 5.5% HAD MINOR STROKES (TRANSIENT ISCHEMIC EPISODES), 18.1% HAD LOWER LIMB CLAUDICATION, 20.5% LEG ULCERS, 4.4% HAD H/O CARDIAC SURGERY, 4.8% ANGIOPLASTY, AND 15.1% HAD DIABETES RETINOPATHY. COMPLICATIONS WERE HIGHER IN RURAL THAN IN URBAN AREAS, HIGHER IN PEOPLE WITH EXTENDED DURATION OF DIABETES. INTEGRATED YOGA MODULE FOR THREE MONTHS (ONE HOUR DAILY) SHOWED SIGNIFICANTLY BETTER REDUCTION IN SYMPTOMS RELATED TO COMPLICATIONS AS COMPARED TO CONTROL GROUP (P < .001). CONCLUSION: THE ALARMING HIGH PREVALENCE OF COMPLICATIONS IN DIABETES POPULATION CALLS FOR URGENT ACTION, WHERE YOGA MAY SHOW THE BENEFITS IN REDUCTION OF SYMPTOMS OF COMPLICATIONS.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
19  926  26 EFFECTIVENESS OF YOGA LIFESTYLE ON LIPID METABOLISM IN A VULNERABLE POPULATION-A COMMUNITY BASED MULTICENTER RANDOMIZED CONTROLLED TRIAL. BACKGROUND: DYSLIPIDEMIA POSES A HIGH RISK FOR CARDIOVASCULAR DISEASE AND STROKE IN TYPE 2 DIABETES (T2DM). THERE ARE NO STUDIES ON THE IMPACT OF A VALIDATED INTEGRATED YOGA LIFESTYLE PROTOCOL ON LIPID PROFILES IN A HIGH-RISK DIABETES POPULATION. METHODS: HERE, WE REPORT THE RESULTS OF LIPID PROFILE VALUES OF 11,254 (YOGA 5932 AND CONTROL 5322) ADULTS (20-70 YEARS) OF BOTH GENDERS WITH HIGH RISK (>/=60 ON INDIAN DIABETES RISK SCORE) FOR DIABETES FROM A NATIONWIDE RURAL AND URBAN COMMUNITY-BASED TWO GROUP (YOGA AND CONVENTIONAL MANAGEMENT) CLUSTER RANDOMIZED CONTROLLED TRIAL. THE YOGA GROUP PRACTICED A VALIDATED INTEGRATED YOGA LIFESTYLE PROTOCOL (DYP) IN NINE DAY CAMPS FOLLOWED BY DAILY ONE-HOUR PRACTICE. BIOCHEMICAL PROFILING INCLUDED GLYCATED HEMOGLOBIN AND LIPID PROFILES BEFORE AND AFTER THREE MONTHS. RESULTS: THERE WAS A SIGNIFICANT DIFFERENCE BETWEEN GROUPS (P < 0.001 ANCOVA) WITH IMPROVED SERUM TOTAL CHOLESTEROL, TRIGLYCERIDES, LOW-DENSITY LIPOPROTEIN, AND HIGH-DENSITY LIPOPROTEIN IN THE YOGA GROUP COMPARED TO THE CONTROL GROUP. FURTHER, THE REGULATORY EFFECT OF YOGA WAS NOTED WITH A SIGNIFICANT DECREASE OR INCREASE IN THOSE WITH HIGH OR LOW VALUES OF LIPIDS, RESPECTIVELY, WITH MARGINAL OR NO CHANGE IN THOSE WITHIN THE NORMAL RANGE. CONCLUSION: YOGA LIFESTYLE IMPROVES AND REGULATES (LOWERED IF HIGH, INCREASED IF LOW) THE BLOOD LIPID LEVELS IN BOTH GENDERS OF PREDIABETIC AND DIABETIC INDIVIDUALS IN BOTH RURAL AND URBAN INDIAN COMMUNITIES.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
20 1212  32 EXPLORING KNOWLEDGE, ATTITUDE AND PRACTICE REGARDING YOGA AMONG PATIENTS ATTENDING CARDIOLOGY AND NEUROLOGY CLINICS IN A TERTIARY CARE HOSPITAL IN NORTHERN INDIA. BACKGROUND THE USE OF COMPLEMENTARY AND ALTERNATIVE MEDICINE, PARTICULARLY YOGA IS INCREASING IN NON-COMMUNICABLE DISEASES (NCDS). WE ASSESSED THE OVERALL AWARENESS REGARDING YOGA AMONG PATIENTS AND THEIR OPINION ABOUT IT AS AN ADJUNCT THERAPY FOR NCDS. METHODS WE INCLUDED 384 PATIENTS ATTENDING THE CARDIOLOGY AND NEUROLOGY CLINICS AT A TERTIARY CARE CENTRE IN NORTHERN INDIA. A QUESTIONNAIRE WAS DEVELOPED TO ASSESS THE KNOWLEDGE, ATTITUDE AND PRACTICE OF YOGA AS A THERAPY. RESULTS NINETY PER CENT OF PATIENTS WERE AWARE OF YOGA, MAINLY THROUGH PRINT AND ELECTRONIC MEDIA. OF THE SURVEYED PATIENTS, 22% PRACTISED YOGA. LACK OF TIME AND KNOWLEDGE WERE CITED AS THE MAIN REASONS FOR NON-PRACTICE AMONG THE NON-PRACTISING PATIENTS (88%), OF WHICH 82% BELIEVED THAT YOGA COULD BE PRACTISED ALONG WITH MODERN MEDICINE. IN ADDITION, 61% WERE READY TO ACCEPT TREATMENT IF OFFERED AT THE SURVEYED TERTIARY CARE CENTRE. CONCLUSIONS ADEQUATE KNOWLEDGE, AWARENESS AND ATTITUDE TOWARDS YOGA APPEARS TO BE PRESENT IN CONTRAST TO THE LOW PRACTICE AMONG THE PATIENT POPULATION SURVEYED. IF IMPLEMENTED IN AN INTEGRATED FASHION, THE PATIENTS WERE WILLING TO ACCEPT YOGA AS AN ADJUNCT THERAPY FOR THEIR CARDIAC AND NEUROLOGICAL DISORDERS-AN ENCOURAGING SIGN GIVEN THE BURDEN OF NCDS IN INDIA.	2022