1 1904 145 RETARDATION OF CORONARY ATHEROSCLEROSIS WITH YOGA LIFESTYLE INTERVENTION. BACKGROUND: YOGA HAS POTENTIAL FOR BENEFIT FOR PATIENTS WITH CORONARY ARTERY DISEASE THOUGH OBJECTIVE, ANGIOGRAPHIC STUDIES ARE LACKING. MATERIAL AND METHODS: WE EVALUATED POSSIBLE ROLE OF LIFESTYLE MODIFICATION INCORPORATING YOGA, ON RETARDATION OF CORONARY ATHEROSCLEROTIC DISEASE. IN THIS PROSPECTIVE, RANDOMIZED, CONTROLLED TRIAL, 42 MEN WITH ANGIOGRAPHICALLY PROVEN CORONARY ARTERY DISEASE (CAD) WERE RANDOMIZED TO CONTROL (N = 21) AND YOGA INTERVENTION GROUP (N = 21) AND WERE FOLLOWED FOR ONE YEAR. THE ACTIVE GROUP WAS TREATED WITH A USER-FRIENDLY PROGRAM CONSISTING OF YOGA, CONTROL OF RISK FACTORS, DIET CONTROL AND MODERATE AEROBIC EXERCISE. THE CONTROL GROUP WAS MANAGED BY CONVENTIONAL METHODS I.E. RISK FACTOR CONTROL AND AMERICAN HEART ASSOCIATION STEP I DIET. RESULTS: AT ONE YEAR, THE YOGA GROUPS SHOWED SIGNIFICANT REDUCTION IN NUMBER OF ANGINAL EPISODES PER WEEK, IMPROVED EXERCISE CAPACITY AND DECREASE IN BODY WEIGHT. SERUM TOTAL CHOLESTEROL, LDL CHOLESTEROL AND TRIGLYCERIDE LEVELS ALSO SHOWED GREATER REDUCTIONS AS COMPARED WITH CONTROL GROUP. REVASCULARISATION PROCEDURES (CORONARY ANGIOPLASTY OR BYPASS SURGERY) WERE LESS FREQUENTLY REQUIRED IN THE YOGA GROUP (ONE VERSUS EIGHT PATIENTS; RELATIVE RISK = 5.45; P = 0.01). CORONARY ANGIOGRAPHY REPEATED AT ONE YEAR SHOWED THAT SIGNIFICANTLY MORE LESIONS REGRESSED (20% VERSUS 2%) AND LESS LESIONS PROGRESSED (5% VERSUS 37%) IN THE YOGA GROUP (CHI-SQUARE = 24.9; P < 0.0001). THE COMPLIANCE TO THE TOTAL PROGRAM WAS EXCELLENT AND NO SIDE EFFECTS WERE OBSERVED. CONCLUSION: YOGA LIFESTYLE INTERVENTION RETARDS PROGRESSION AND INCREASES REGRESSION OF CORONARY ATHEROSCLEROSIS IN PATIENTS WITH SEVERE CORONARY ARTERY DISEASE. IT ALSO IMPROVES SYMPTOMATIC STATUS, FUNCTIONAL CLASS AND RISK FACTOR PROFILE.	2000	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
2 1298  31 HATHA YOGA AND VASCULAR FUNCTION: RESULTS FROM CROSS-SECTIONAL AND INTERVENTIONAL STUDIES. THE AIM OF THIS STUDY WAS TO DETERMINE THE EFFECT OF HATHA YOGA ON ARTERIAL ELASTICITY AND ENDOTHELIAL FUNCTION. FIRST, A CROSS-SECTIONAL STUDY WAS PERFORMED TO DETERMINE WHETHER YOGA PRACTITIONERS WOULD DEMONSTRATE GREATER ARTERIAL COMPLIANCE AND ENDOTHELIUM-DEPENDENT VASODILATION THAN THEIR SEDENTARY PEERS. SECOND, AN INTERVENTION STUDY INVOLVING 13 SEDENTARY MIDDLE-AGED AND OLDER ADULTS (51 +/- 7 YEARS) WAS PERFORMED TO DETERMINE WHETHER 12 WEEKS OF HATHA YOGA WOULD ELICIT INCREASES IN ARTERIAL COMPLIANCE AND ENDOTHELIAL FUNCTION. IN THE CROSS-SECTIONAL STUDY INVOLVING A TOTAL OF 34 SUBJECTS, THERE WERE NO GROUP DIFFERENCES IN BODY FATNESS, BLOOD LIPID AND LIPOPROTEIN CONCENTRATIONS, CAROTID ARTERY COMPLIANCE OR BRACHIAL ARTERY FLOW-MEDIATED DILATION (FMD). HEMOGLOBIN A1C WAS LOWER IN YOGA PRACTITIONERS THAN IN SEDENTARY ADULTS (P < 0.05). TOTAL CHOLESTEROL AND HEMOGLOBIN A1C DECREASED AFTER THE INTERVENTION (P < 0.05) WHILE CAROTID ARTERY COMPLIANCE AND BRACHIAL ARTERY FMD DID NOT CHANGE. THE RESULTS OF BOTH CROSS-SECTIONAL AND INTERVENTIONAL STUDIES INDICATE THAT REGULAR PRACTICE OF HATHA YOGA IS NOT ASSOCIATED WITH IMPROVEMENTS IN VASCULAR FUNCTIONS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
3 2507  50 YOGA BASED CARDIAC REHABILITATION AFTER CORONARY ARTERY BYPASS SURGERY: ONE-YEAR RESULTS ON LVEF, LIPID PROFILE AND PSYCHOLOGICAL STATES--A RANDOMIZED CONTROLLED STUDY. OBJECTIVE: TO COMPARE THE LONG TERM EFFECTS OF YOGA BASED CARDIAC REHABILITATION PROGRAM WITH ONLY PHYSIOTHERAPY BASED PROGRAM AS AN ADD-ON TO CONVENTIONAL REHABILITATION AFTER CORONARY ARTERY BYPASS GRAFTING (CABG) ON RISK FACTORS. METHODS: IN THIS SINGLE BLIND PROSPECTIVE RANDOMIZED PARALLEL TWO ARMED ACTIVE CONTROL STUDY, 1026 PATIENTS POSTED FOR CABG AT NARAYANA HRUDAYALAYA INSTITUTE OF CARDIAC SCIENCES, BENGALURU (INDIA) WERE SCREENED. OF THESE, 250 MALE PARTICIPANTS (35-65 YEARS) WHO SATISFIED THE SELECTION CRITERIA AND CONSENTED WERE RANDOMIZED INTO TWO GROUPS. WITHIN AND BETWEEN GROUP COMPARISONS WERE DONE AT THREE POINTS OF FOLLOW UP (I.E. 6TH WEEK, 6TH MONTH, AND 12TH MONTH) BY USING WILCOXON'S SIGNED RANKS TEST AND MANN WHITNEY U TEST RESPECTIVELY. RESULTS: YOGA GROUP HAD SIGNIFICANTLY (P = 0.001, MANN WHITNEY) BETTER IMPROVEMENT IN LVEF THAN CONTROL GROUP IN THOSE WITH ABNORMAL BASELINE EF (<53%) AFTER 1 YEAR. THERE WAS A BETTER REDUCTION IN BMI IN THE YOGA GROUP (P = 0.038, BETWEEN GROUPS) IN THOSE WITH HIGH BASELINE BMI (>/=23) AFTER 12 MONTHS. YOGA GROUP SHOWED SIGNIFICANT (P = 0.008, WILCOXON'S) REDUCTION IN BLOOD GLUCOSE AT ONE YEAR IN THOSE WITH HIGH BASELINE FBS >/=110 MG/DL. THERE WAS SIGNIFICANTLY BETTER IMPROVEMENT IN YOGA THAN THE CONTROL GROUP IN HDL (P = 0.003), LDL (P = 0.01) AND VLDL (P = 0.03) IN THOSE WITH ABNORMAL BASELINE VALUES. THERE WAS SIGNIFICANTLY BETTER IMPROVEMENT (P = 0.02, BETWEEN GROUPS) IN POSITIVE AFFECT IN YOGA GROUP. WITHIN YOGA GROUP, THERE WAS SIGNIFICANT DECREASE IN PERCEIVED STRESS (P = 0.001), ANXIETY (P = 0.001), DEPRESSION (P = 0.001), AND NEGATIVE AFFECT (P = 0.03) WHILE IN THE CONTROL GROUP THERE WAS REDUCTION (P = 0.003) ONLY IN SCORES ON ANXIETY. CONCLUSION: ADDITION OF YOGA BASED RELAXATION TO CONVENTIONAL POST-CABG CARDIAC REHABILITATION HELPS IN BETTER MANAGEMENT OF RISK FACTORS IN THOSE WITH ABNORMAL BASELINE VALUES AND MAY HELP IN PREVENTING RECURRENCE.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
4  867  56 EFFECT OF YOGA REGIMEN ON LUNG FUNCTIONS INCLUDING DIFFUSION CAPACITY IN CORONARY ARTERY DISEASE PATIENTS: A RANDOMIZED CONTROLLED STUDY. BACKGROUND: LUNG FUNCTIONS ARE FOUND TO BE IMPAIRED IN CORONARY ARTERY DISEASE (CAD), CONGESTIVE HEART FAILURE, LEFT VENTRICULAR DYSFUNCTION, AND AFTER CARDIAC SURGERY. DIFFUSION CAPACITY PROGRESSIVELY WORSENS AS THE SEVERITY OF CAD INCREASES DUE TO REDUCTION IN LUNG TISSUE PARTICIPATING IN GAS EXCHANGE. AIMS AND OBJECTIVES: PRANAYAMA BREATHING EXERCISES AND YOGIC POSTURES MAY PLAY AN IMPRESSIVE ROLE IN IMPROVING CARDIO-RESPIRATORY EFFICIENCY AND FACILITATING GAS DIFFUSION AT THE ALVEOLO-CAPILLARY MEMBRANE. THIS STUDY WAS DONE TO SEE THE EFFECT OF YOGA REGIMEN ON LUNG FUNCTIONS PARTICULARLY DIFFUSION CAPACITY IN CAD PATIENTS. MATERIALS AND METHODS: A TOTAL OF 80 STABLE CAD PATIENTS BELOW 65 YEARS OF AGE OF BOTH SEXES WERE SELECTED AND RANDOMIZED INTO TWO GROUPS OF 40 EACH. GROUP I CAD PATIENTS WERE GIVEN YOGA REGIMEN FOR 3 MONTHS WHICH CONSISTED OF YOGIC POSTURES, PRANAYAMA BREATHING EXERCISES, DIETARY MODIFICATION, AND HOLISTIC TEACHING ALONG WITH THEIR CONVENTIONAL MEDICINE WHILE GROUP II CAD PATIENTS WERE PUT ONLY ON CONVENTIONAL MEDICINE. LUNG FUNCTIONS INCLUDING DIFFUSION CAPACITY WERE RECORDED THRICE IN BOTH THE GROUPS: 0 DAY AS BASELINE, 22(ND) DAY AND ON 90(TH) DAY BY USING COMPUTERIZED MS MEDISOFT CARDIO-RESPIRATORY INSTRUMENT, HYP'AIR COMPACT MODEL OF CARDIO-RESPIRATORY TESTING MACHINE WAS MANUFACTURED BY P K MORGAN, INDIA. THE RECORDED PARAMETERS WERE STATISTICALLY ANALYZED BY REPEATED MEASURES ANOVA FOLLOWED BY TUKEY'S TEST IN BOTH THE GROUPS. CARDIOVASCULAR PARAMETERS WERE ALSO COMPARED BEFORE AND AFTER INTERVENTION IN BOTH THE GROUPS. RESULTS: STATISTICALLY SIGNIFICANT IMPROVEMENTS WERE SEEN IN SLOW VITAL CAPACITY, FORCED VITAL CAPACITY, PEAK EXPIRATORY FLOW RATE, MAXIMUM VOLUNTARY VENTILATION, AND DIFFUSION FACTOR/ TRANSFER FACTOR OF LUNG FOR CARBON MONOXIDE AFTER 3 MONTHS OF YOGA REGIMEN IN GROUP I. FORCED EXPIRATORY VOLUME IN 1(ST) SEC (FEV1), AND FEV1 % ALSO SHOWED A TREND TOWARD IMPROVEMENT ALTHOUGH NOT STATISTICALLY SIGNIFICANT. HR, SBP AND DBP ALSO SHOWED SIGNIFICANT IMPROVEMENT IN GROUP-I PATIENTS WHO FOLLOWED YOGA REGIMEN. CONCLUSIONS: YOGA REGIMEN WAS FOUND TO IMPROVE LUNG FUNCTIONS AND DIFFUSION CAPACITY IN CAD PATIENTS BESIDES IMPROVING CARDIOVASCULAR FUNCTIONS. THUS, IT CAN BE USED AS A COMPLIMENTARY OR ADJUNCT THERAPY ALONG WITH THE CONVENTIONAL MEDICINE FOR THEIR TREATMENT AND REHABILITATION.	2015	
                                                                                                                                                                                                                                                                                                                   
5  739  35 EFFECT OF RAJA YOGA MEDITATION ON THE LIPID PROFILE OF POST-MENOPAUSAL WOMEN. BACKGROUND: CORONARY ARTERY DISEASE IS AN IMPORTANT CAUSE OF DEATH AND DISABILITY AMONG OLDER WOMEN. MODIFICATION IN LIPID PROFILE LOWERS THE RISK OF CORONARY ARTERY DISEASE. IT IS CLAIMED THAT YOGA AND TRANSCENDENTAL MEDITATION HAVE A CHOLESTEROL LOWERING EFFECT. THIS STUDY WAS DESIGNED TO ASSESS THE EFFECT OF RAJA YOGA MEDITATION OF BRAHMAKUMARIS WHICH IS VERY SIMPLE TO PRACTICE, ON SERUM LIPIDS IN NORMAL INDIAN WOMEN. METHODS AND RESULTS: 49 NORMAL FEMALE VOLUNTEERS WERE THE SUBJECTS. THEY WERE DIVIDED INTO PRE-MENOPAUSAL (N=23) AND POST-MENOPAUSAL (N=26) GROUPS. THEY WERE FURTHER DIVIDED INTO NON-MEDITATORS (WHO HAD NEVER DONE ANY KIND OF MEDITATION), SHORT-TERM MEDITATORS (MEDITATING FOR 6 MONTHS TO 5 YEARS) AND LONG-TERM MEDITATORS (MEDITATING FOR MORE THAN 5 YEARS). LIPID PROFILE WAS ASSESSED USING THEIR RESPECTIVE REAGENT SETS. SERUM CHOLESTEROL, TRIGLYCERIDE AND LOW-DENSITY LIPOPROTEIN-CHOLESTEROL IN NONMEDITATORS WERE SIGNIFICANTLY MORE IN POST-MENOPAUSAL WOMEN AS COMPARED TO PRE-MENOPAUSAL WOMEN. SERUM CHOLESTEROL AND LOW DENSITY LIPOPROTEIN-CHOLESTEROL WERE SIGNIFICANTLY LOWERED IN BOTH SHORT AND LONG TERM MEDITATORS AS COMPARED TO NON-MEDITATORS IN POST-MENOPAUSAL WOMEN. NO SIGNIFICANT DIFFERENCE WAS OBSERVED IN LIPID PROFILE IN PRE-MENOPAUSAL WOMEN. CONCLUSION: RAJA YOGA MEDITATION LOWERED SERUM CHOLESTEROL AND LOW-DENSITY LIPOPROTEIN-CHOLESTEROL IN POST-MENOPAUSAL WOMEN THUS REDUCING THE RISK OF CORONARY ARTERY DISEASE IN THEM.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
6 2072  44 THE EFFECT OF A SIX-WEEK PROGRAM OF YOGA AND MEDITATION ON BRACHIAL ARTERY REACTIVITY: DO PSYCHOSOCIAL INTERVENTIONS AFFECT VASCULAR TONE? BACKGROUND: CHRONIC STRESS IS ESTIMATED TO INCREASE THE RISK OF CARDIOVASCULAR (CV) EVENTS TWO-FOLD. ALTHOUGH STRESS REDUCTION HAS BEEN LINKED TO A REDUCTION IN CV EVENTS, LITTLE IS KNOWN REGARDING ITS EXACT MECHANISM OF BENEFIT. HYPOTHESIS: YOGA AND MEDITATION WILL IMPROVE PARAMETERS OF ENDOTHELIAL FUNCTION. METHODS: WE EXAMINED THE EFFECTS OF YOGA AND MEDITATION ON HEMODYNAMIC AND LABORATORY PARAMETERS AS WELL AS ON ENDOTHELIAL FUNCTION IN A 6-WEEK PILOT STUDY. SYSTOLIC AND DIASTOLIC BLOOD PRESSURES, HEART RATE, BODY MASS INDEX (BMI), FASTING GLUCOSE, LIPIDS, HS C-REACTIVE PROTEIN (CRP), AND ENDOTHELIAL FUNCTION (AS ASSESSED BY BRACHIAL ARTERY REACTIVITY) WERE ALL STUDIED AT BASELINE AND AFTER 6 WEEKS OF YOGA PRACTICE. RESULTS: A COURSE IN YOGA AND MEDITATION WAS GIVEN TO THE SUBJECTS FOR 1.5 H THREE TIMES WEEKLY FOR 6 WEEKS AND SUBJECTS WERE INSTRUCTED TO CONTINUE THEIR EFFORTS AT HOME. THIS PROSPECTIVE COHORT STUDY INCLUDED 33 SUBJECTS (MEAN AGE 55 +/- 11 YEARS) BOTH WITH (30%) AND WITHOUT (70%) ESTABLISHED CORONARY ARTERY DISEASE (CAD). THERE WERE SIGNIFICANT REDUCTIONS IN BLOOD PRESSURE, HEART RATE, AND BMI IN THE TOTAL COHORT WITH YOGA. NONE OF THE LABORATORY PARAMETERS CHANGED SIGNIFICANTLY WITH YOGA. FOR THE TOTAL COHORT THERE WAS NO SIGNIFICANT IMPROVEMENT IN ENDOTHELIAL-DEPENDENT VASODILATATION WITH YOGA TRAINING AND MEDITATION COMPARED WITH BASELINE (16.7% RELATIVE IMPROVEMENT FROM 7.2-8.4%; P = 0.3). IN THE GROUP WITH CAD, ENDOTHELIAL-DEPENDENT VASODILATATION IMPROVED 69% WITH YOGA TRAINING (6.38-10.78%; P = 0.09). CONCLUSION: YOGA AND MEDITATION APPEAR TO IMPROVE ENDOTHELIAL FUNCTION IN SUBJECTS WITH CAD.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
7  384  61 BENEFICIAL EFFECTS OF YOGA LIFESTYLE ON REVERSIBILITY OF ISCHAEMIC HEART DISEASE: CARING HEART PROJECT OF INTERNATIONAL BOARD OF YOGA. OBJECTIVES: YOGA BASED LIFESTYLE MODIFICATIONS HAVE BEEN EARLIER SHOWN TO BE BENEFICIAL IN CORONARY ARTERY DISEASE IN A SMALL NUMBER OF PATIENTS. WE EVALUATED THE ROLE OF LIFESTYLE MODIFICATION BASED ON YOGA TECHNIQUES, STRESS MANAGEMENT AND DIETARY MODIFICATIONS IN RETARDATION OF CORONARY ARTERY DISEASE. METHODS: THIS PROSPECTIVE, CONTROLLED, OPEN TRIAL INCLUDED ANGIOGRAPHICALLY PROVEN CORONARY ARTERY DISEASE PATIENTS (71 PATIENTS IN STUDY GROUP AND 42 PATIENTS IN CONTROL GROUP). THEY WERE ASSESSED CLINICALLY, BY BIOCHEMICAL PARAMETERS, STRESS MYOCARDIAL PERFUSION AND FUNCTION STUDIES AND CORONARY ANGIOGRAPHY AND ON PSYCHOLOGICAL PARAMETERS. THE STUDY GROUP PATIENTS WERE GIVEN A FAMILY BASED YOGA PROGRAMME WHICH INCLUDED, CONTROL OF RISK FACTORS, DIETARY MODIFICATIONS AND STRESS MANAGEMENT FOR A PERIOD OF ONE YEAR. THE PATIENTS WERE ASSESSED AT BASELINE, AT FREQUENT INTERVALS AND AT THE END OF ONE YEAR. RESULTS: AT THE END OF ONE YEAR OF YOGA TRAINING, STATISTICAL SIGNIFICANT CHANGES (P<0.05) WERE FOUND IN SERUM TOTAL CHOLESTEROL (REDUCTION BY 23.3% IN STUDY GROUP PATIENTS AS COMPARED TO 4.4% IN CONTROLS); SERUM LDL CHOLESTEROL (REDUCTION OF 26% IN STUDY GROUP PATIENTS AS COMPARED TO 2.6% IN THE CONTROL GROUP), REGRESSION OF DISEASE (43.7% OF STUDY GROUP PATIENTS V/S 31% CONTROL GROUP ON MPI AND 70.4% OF STUDY GROUP V/S 28% OF CONTROL GROUP ON ANGIOGRAPHY) ARREST OF PROGRESSION (46.5% STUDY GROUP V/S 33.3% CONTROL GROUP ON MPI) AND PROGRESSION (9.9% OF STUDY GROUP VS 35.7% OF CONTROLS ON MPI, 29.6% OF STUDY GROUP V/S 60.0% OF CONTROLS ON ANGIOGRAPHY). AT THE END OF THE STUDY IMPROVEMENT IN ANXIETY SCORES WAS CONCORDANT WITH THE IMPROVEMENT SEEN IN THE MPI. NO UNTOWARD EFFECTS OF THE THERAPY WERE OBSERVED. CONCLUSION: YOGA BASED LIFESTYLE MODIFICATIONS HELP IN REGRESSION OF CORONARY LESIONS AND IN IMPROVING MYOCARDIAL PERFUSION. THIS IS TRANSLATED INTO CLINICAL BENEFITS AND SYMPTOMATIC IMPROVEMENT.	2004	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
8   39  44 A BRIEF BUT COMPREHENSIVE LIFESTYLE EDUCATION PROGRAM BASED ON YOGA REDUCES RISK FACTORS FOR CARDIOVASCULAR DISEASE AND DIABETES MELLITUS. OBJECTIVES: THE OBJECTIVE OF THE STUDY WAS TO STUDY THE SHORT-TERM IMPACT OF A BRIEF LIFESTYLE INTERVENTION BASED ON YOGA ON SOME OF THE BIOCHEMICAL INDICATORS OF RISK FOR CARDIOVASCULAR DISEASE AND DIABETES MELLITUS. DESIGN: THE VARIABLES OF INTEREST WERE MEASURED AT THE BEGINNING (DAY 1) AND END (DAY 10) OF THE INTERVENTION USING A PRE-POST DESIGN. SETTING: THE STUDY IS THE RESULT OF OPERATIONAL RESEARCH CARRIED OUT IN OUR INTEGRAL HEALTH CLINIC (IHC). THE IHC IS AN OUTPATIENT FACILITY WHICH CONDUCTS 8-DAY LIFESTYLE MODIFICATION PROGRAMS BASED ON YOGA FOR PREVENTION AND MANAGEMENT OF CHRONIC DISEASE. A NEW COURSE BEGINS EVERY ALTERNATE WEEK OF THE YEAR. SUBJECTS: THE STUDY IS BASED ON DATA COLLECTED ON 98 SUBJECTS (67 MALE, 31 FEMALE), AGES 20-74 YEARS, WHO ATTENDED ONE OF OUR PROGRAMS. THE SUBJECTS WERE A HETEROGENEOUS GROUP OF PATIENTS WITH HYPERTENSION, CORONARY ARTERY DISEASE, DIABETES MELLITUS, AND A VARIETY OF OTHER ILLNESSES. INTERVENTION: THE INTERVENTION CONSISTED OF ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), RELAXATION TECHNIQUES, GROUP SUPPORT, INDIVIDUALIZED ADVICE, LECTURES AND FILMS ON THE PHILOSOPHY OF YOGA AND THE PLACE OF YOGA IN DAILY LIFE, MEDITATION, STRESS MANAGEMENT, NUTRITION, AND KNOWLEDGE ABOUT THE ILLNESS. OUTCOME MEASURES: THE OUTCOME MEASURES WERE FASTING PLASMA GLUCOSE AND SERUM LIPOPROTEIN PROFILE. THESE VARIABLES WERE DETERMINED IN FASTING BLOOD SAMPLES, TAKEN ON THE FIRST AND LAST DAY OF THE COURSE. RESULTS: FASTING PLASMA GLUCOSE, SERUM TOTAL CHOLESTEROL, LOW-DENSITY LIPOPROTEIN (LDL) CHOLESTEROL, VERY- LDL CHOLESTEROL, THE RATIO OF TOTAL CHOLESTEROL TO HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL, AND TOTAL TRIGLYCERIDES WERE SIGNIFICANTLY LOWER, AND HDL CHOLESTEROL SIGNIFICANTLY HIGHER, ON THE LAST DAY OF THE COURSE COMPARED TO THE FIRST DAY OF THE COURSE. THE CHANGES WERE MORE MARKED IN SUBJECTS WITH HYPERGLYCEMIA OR HYPERCHOLESTEROLEMIA. CONCLUSIONS: THE OBSERVATIONS SUGGEST THAT A SHORT LIFESTYLE MODIFICATION AND STRESS MANAGEMENT EDUCATION PROGRAM LEADS TO FAVORABLE METABOLIC EFFECTS WITHIN A PERIOD OF 9 DAYS.	2005	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
9 1045  36 EFFECTS OF YOGA INTERVENTIONS PRACTISED IN HEATED AND THERMONEUTRAL CONDITIONS ON ENDOTHELIUM-DEPENDENT VASODILATATION: THE BIKRAM YOGA HEART STUDY. NEW FINDINGS: WHAT IS THE CENTRAL QUESTION OF THIS STUDY? DOES THE HEATED PRACTICE ENVIRONMENT ENHANCE THE EFFECTS OF BIKRAM YOGA ON ENDOTHELIUM-DEPENDENT VASODILATATION IN HEALTHY, MIDDLE-AGED ADULTS? WHAT IS THE MAIN FINDING AND ITS IMPORTANCE? THE PRIMARY FINDING FROM THIS INVESTIGATION IS THAT THE HATHA YOGA POSTURES IN THE BIKRAM YOGA SERIES PRODUCE SIMILAR ENHANCEMENTS IN ENDOTHELIUM-DEPENDENT VASODILATATION IN HEALTHY, MIDDLE-AGED ADULTS REGARDLESS OF ENVIRONMENTAL TEMPERATURE. THESE FINDINGS HIGHLIGHT THE EFFICACY OF YOGA POSTURES IN PRODUCING IMPROVEMENTS IN VASCULAR HEALTH AND DOWNPLAY THE NECESSITY OF THE HEATED PRACTICE ENVIRONMENT IN INDUCING VASCULAR ADAPTATIONS. ABSTRACT: WE HAVE PREVIOUSLY DOCUMENTED IMPROVEMENTS IN ENDOTHELIUM-DEPENDENT VASODILATATION WITH A BIKRAM (HOT) YOGA INTERVENTION IN MIDDLE-AGED ADULTS. AT PRESENT, THE EFFECT OF ENVIRONMENTAL TEMPERATURE IN HOT YOGA ON ENDOTHELIAL FUNCTION IS UNKNOWN. THE PURPOSE OF THIS INVESTIGATION WAS TO DETERMINE THE EFFECTS OF BIKRAM YOGA INTERVENTIONS PERFORMED IN HEATED OR THERMONEUTRAL CONDITIONS ON ENDOTHELIUM-DEPENDENT VASODILATATION. FIFTY-TWO SEDENTARY BUT APPARENTLY HEALTHY ADULTS AGED 40-60 YEARS WERE RANDOMLY ASSIGNED TO ONE OF THREE GROUPS: BIKRAM YOGA PRACTISED AT 40.5 DEGREES C (N = 19), BIKRAM YOGA PRACTISED AT 23 DEGREES C (N = 14) OR SEDENTARY TIME CONTROL (N = 19). THE YOGA INTERVENTIONS CONSISTED OF 90 MIN BIKRAM YOGA CLASSES THREE TIMES A WEEK FOR 12 WEEKS. ENDOTHELIUM-DEPENDENT VASODILATATION WAS MEASURED NON-INVASIVELY USING BRACHIAL ARTERY FLOW-MEDIATED DILATATION (FMD). BODY FAT PERCENTAGE DETERMINED VIA DUAL-ENERGY X-RAY ABSORPTIOMETRY WAS SIGNIFICANTLY LOWER IN THE HOT YOGA GROUP AFTER THE INTERVENTION THAN IN THE THERMONEUTRAL YOGA AND CONTROL CONDITIONS. BRACHIAL ARTERY FMD INCREASED (P < 0.05) IN THE THERMONEUTRAL YOGA GROUP AND TENDED TO INCREASE IN THE HOT YOGA GROUP (P = 0.056). NO CHANGES OCCURRED IN THE CONTROL GROUP. THERE WERE NO SIGNIFICANT DIFFERENCES IN FMD CHANGE SCORES BETWEEN GROUPS. WE CONCLUDE THAT BIKRAM YOGA PRACTISED IN THERMONEUTRAL CONDITIONS IMPROVED ENDOTHELIUM-DEPENDENT VASODILATATION IN HEALTHY, MIDDLE-AGED ADULTS. THESE NEW FINDINGS HIGHLIGHT THE EFFECTIVENESS OF HATHA YOGA POSTURES ALONE, IN THE ABSENCE OF A HEATED PRACTICE ENVIRONMENT, IN IMPROVING VASCULAR HEALTH AND ARE OF CLINICAL SIGNIFICANCE GIVEN THE INCREASED PROPENSITY FOR HEAT INTOLERANCE IN AGEING ADULTS.	2018	
                                                                                                                                                                                                                                         
10 2075  38 THE EFFECT OF BIKRAM YOGA ON ARTERIAL STIFFNESS IN YOUNG AND OLDER ADULTS. BACKGROUND AND OBJECTIVE: BIKRAM YOGA IS THE MOST POPULAR FORM OF HOT YOGA, DESPITE THE LIMITED INFORMATION AVAILABLE ON ITS CARDIOVASCULAR BENEFITS. THIS STUDY SOUGHT TO DETERMINE THE EFFECT OF BIKRAM YOGA ON ARTERIAL STIFFNESS AND INSULIN RESISTANCE IN YOUNG AND OLDER ADULTS. METHODS: TWENTY-FOUR YOUNG (MEAN AGE+/-STANDARD DEVIATION, 30+/-1 YEARS) AND 18 MIDDLE-AGED AND OLDER (MEAN AGE, 53+/-2 YEARS) ADULTS COMPLETED AN 8-WEEK BIKRAM YOGA INTERVENTION. BIKRAM YOGA CLASSES WERE PERFORMED FOR 90 MINUTES PER SESSION, THREE TIMES PER WEEK, IN A ROOM HEATED TO 40.5 DEGREES C WITH 40%--60% RELATIVE HUMIDITY. RESULTS: BODY MASS, BODY FAT PERCENTAGE, BLOOD PRESSURE, AND FASTING BLOOD GLUCOSE AND TRIGLYCERIDE CONCENTRATIONS DID NOT SIGNIFICANTLY CHANGE AS A RESULT OF THE INTERVENTION IN EITHER THE YOUNG OR THE OLDER GROUP. TRUNK FLEXIBILITY, AS MEASURED BY THE SIT-AND-REACH TEST, INCREASED IN BOTH GROUPS (P<0.01). TOTAL (P<0.05) AND LOW-DENSITY LIPOPROTEIN CHOLESTEROL (P<0.05) LEVELS, PLASMA INSULIN CONCENTRATIONS (P<0.01), AND SCORES ON THE HOMEOSTATIC MODEL OF THE ASSESSMENT OF INSULIN RESISTANCE (P<0.01) DECREASED IN OLDER ADULTS, WHEREAS TOTAL AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL CONCENTRATIONS WERE REDUCED IN YOUNG ADULTS (ALL P<0.05). CAROTID ARTERY COMPLIANCE (P<0.05) WAS INCREASED AND BETA-STIFFNESS INDEX DECREASED IN YOUNG (P<0.05) BUT NOT IN OLDER ADULTS. CAROTID PULSE PRESSURE DID NOT SIGNIFICANTLY CHANGE IN EITHER GROUP. CONCLUSION: A RELATIVELY SHORT-TERM BIKRAM YOGA INTERVENTION IMPROVED ARTERIAL STIFFNESS IN YOUNG BUT NOT OLDER ADULTS AND SIGNIFICANTLY REDUCED INSULIN RESISTANCE INDEX IN OLDER BUT NOT YOUNG ADULTS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
11 1030  40 EFFECTS OF YOGA EXERCISE ON SERUM ADIPONECTIN AND METABOLIC SYNDROME FACTORS IN OBESE POSTMENOPAUSAL WOMEN. OBJECTIVE: REGULAR AND CONTINUOUS YOGA EXERCISE IS ONE OF THE MOST IMPORTANT NONPHARMACOLOGICAL METHODS OF IMPROVING SERUM LIPID CONCENTRATIONS, ADIPOSE TISSUE, AND METABOLIC SYNDROME FACTORS. THE PURPOSE OF THIS STUDY WAS TO ANALYZE THE EFFECTS OF YOGA EXERCISE ON SERUM ADIPONECTIN AND METABOLIC SYNDROME FACTORS IN OBESE POSTMENOPAUSAL KOREAN WOMEN. METHODS: SIXTEEN HEALTHY POSTMENOPAUSAL WOMEN AGED 54.50 +/- 2.75 YEARS WITH MORE THAN 36% BODY FAT WERE RANDOMLY ASSIGNED TO EITHER A YOGA EXERCISE GROUP (N = 8) OR TO A "NO EXERCISE" CONTROL GROUP (N = 8). THE VARIABLES OF BODY COMPOSITION, VISCERAL FAT, SERUM ADIPONECTIN, AND METABOLIC SYNDROME FACTORS WERE MEASURED IN ALL THE PARTICIPANTS BEFORE AND AFTER THE 16-WEEK STUDY. RESULTS: BODY WEIGHT, PERCENTAGE OF BODY FAT, LEAN BODY MASS, BODY MASS INDEX, WAIST CIRCUMFERENCE, AND VISCERAL FAT AREA HAD SIGNIFICANTLY DECREASED. HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND ADIPONECTIN HAD SIGNIFICANTLY INCREASED, BUT TOTAL CHOLESTEROL, TRIGLYCERIDE, LOW-DENSITY LIPOPROTEIN CHOLESTEROL, BLOOD PRESSURE, INSULIN, GLUCOSE, AND HOMOEOSTASIS MODEL ASSESSMENT-INSULIN RESISTANCE HAD SIGNIFICANTLY DECREASED. SERUM ADIPONECTIN CONCENTRATIONS WERE SIGNIFICANTLY CORRELATED WITH WAIST CIRCUMFERENCE, HIGH-DENSITY LIPOPROTEIN CHOLESTEROL, DIASTOLIC BLOOD PRESSURE, AND HOMOEOSTASIS MODEL ASSESSMENT-INSULIN RESISTANCE IN THE POSTYOGA EXERCISE GROUP. CONCLUSIONS: OUR FINDINGS INDICATE THAT YOGA EXERCISE IMPROVES ADIPONECTIN LEVEL, SERUM LIPIDS, AND METABOLIC SYNDROME RISK FACTORS IN OBESE POSTMENOPAUSAL WOMEN. CONSEQUENTLY, YOGA EXERCISE WILL BE EFFECTIVE IN PREVENTING CARDIOVASCULAR DISEASE CAUSED BY OBESITY IN OBESE POSTMENOPAUSAL KOREAN WOMEN.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
12 1374  43 IMPACT OF AN INTEGRATED YOGA THERAPY PROTOCOL ON INSULIN RESISTANCE AND GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. OBJECTIVE: DIABETES MELLITUS (DM), CHARACTERIZED BY CHRONIC HYPERGLYCEMIA, IS ATTRIBUTED TO RELATIVE INSULIN DEFICIENCY OR RESISTANCE, OR BOTH. STUDIES HAVE SHOWN THAT YOGA CAN MODULATE PARAMETERS OF INSULIN RESISTANCE. THE PRESENT STUDY EXPLORED THE POSSIBLE BENEFICIAL EFFECTS OF INTEGRATED YOGA THERAPY WITH REFERENCE TO GLYCEMIC CONTROL AND INSULIN RESISTANCE (IR) IN INDIVIDUALS WITH DIABETES MAINTAINED ON STANDARD ORAL MEDICAL CARE WITH YOGA THERAPY, COMPARED TO THOSE ON STANDARD ORAL MEDICAL CARE ALONE. METHODS: IN THIS STUDY, THE SUBJECTS ON YOGA INTERVENTION COMPRISED 35 TYPE 2 DIABETICS, AND AN EQUAL NUMBER OF VOLUNTEERS CONSTITUTED THE CONTROL GROUP. SUBJECTS RANGED IN AGE FROM 30 TO 70 YEARS, WITH HEMOGLOBIN A1C (HBA1C) TEST MORE THAN 7%, AND WERE MAINTAINED ON DIABETIC DIET AND ORAL HYPOGLYCEMIC AGENTS. BLOOD SAMPLES WERE DRAWN PRIOR TO AND AFTER 120 DAYS OF INTEGRATED YOGA THERAPY INTERVENTION. FASTING BLOOD GLUCOSE (FBG), POST-PRANDIAL BLOOD GLUCOSE (PPBG), HBA1C, INSULIN, AND LIPID PROFILE WERE ASSESSED IN BOTH THE INTERVENTION AND CONTROL GROUPS. RESULTS: THE INTERVENTION GROUP REVEALED SIGNIFICANT IMPROVEMENTS IN BODY MASS INDEX (BMI) (0.7 KG/M(2) MEDIAN DECREASE; P=0.001), FBG (20 MG/DL MEDIAN DECREASE; P<0.001), PPBG (33 MG/DL MEDIAN DECREASE; P<0.001), HBA1C (0.4% MEDIAN DECREASE; P<0.001), HOMEOSTATIC MODEL ASSESSMENT FOR INSULIN RESISTANCE (HOMA-IR) (1.2 MEDIAN DECREASE; P<0.001), CHOLESTEROL (13 MG/DL MEDIAN DECREASE, P=0.006), TRIACYLGLYCEROL (22 MG/DL MEDIAN DECREASE; P=0.027), LOW-DENSITY LIPOPROTEIN (6 MG/DL MEDIAN DECREASE; P=0.004), AND VERY-LOW-DENSITY LIPOPROTEIN LEVELS (4 MG/DL MEDIAN DECREASE; P=0.032). INCREASES IN HIGH-DENSITY LIPOPROTEIN AFTER 120 DAYS WERE NOT SIGNIFICANT (6 MG/DL MEDIAN INCREASE; P=0.15). HOWEVER, WHEN COMPARED TO CHANGES OBSERVED IN PATIENTS IN THE CONTROL GROUP, ALL THESE IMPROVEMENTS PROVED TO BE SIGNIFICANT. CONCLUSION: ADMINISTRATION OF INTEGRATED YOGA THERAPY TO INDIVIDUALS WITH DIABETES LEADS TO A SIGNIFICANT IMPROVEMENT IN GLYCEMIC CONTROL, INSULIN RESISTANCE, AND KEY BIOCHEMICAL PARAMETERS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
13  993  16 EFFECTS OF HEATED AND THERMONEUTRAL YOGA INTERVENTIONS ON ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS. THE STUDY INVESTIGATED THE EFFICACY OF 12 WEEKS OF HEATED AND THERMONEUTRAL BIKRAM YOGA IN REDUCING ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS. FIFTY-FOUR SEDENTARY ADULTS (AGES 40-60 YEARS) COMPLETED 12 WEEKS OF YOGA AT 40.5 DEGREES C (N = 21), YOGA AT 23 DEGREES C (N = 14) OR TIME CONTROL (N = 19). BRACHIAL-ANKLE PULSE WAVE VELOCITY (PWV) WAS NOT SIGNIFICANTLY ALTERED BY HOT OR THERMONEUTRAL YOGA INTERVENTIONS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
14 1477  55 INTEGRATED YOGA PRACTICE IN CARDIAC REHABILITATION PROGRAM: A RANDOMIZED CONTROL TRIAL. BACKGROUND: CORONARY ARTERY DISEASE (CAD) IS A DETRIMENTAL NONCOMMUNICABLE DISEASE, WHICH IS INCREASING DUE TO SEDENTARY LIFESTYLE AND URBANIZATION IN THE YOUNG POPULATION. IT IS FURTHER ELEVATED WITH RISK FACTORS SUCH AS STRESS, ANXIETY, DEPRESSION, AN INCREASE IN TRIGLYCERIDES, DYSLIPIDEMIA, HYPERGLYCEMIA, HYPERTENSION, AND SO ON, WHICH MANIFESTS AS ATHEROSCLEROTIC DISEASE. YOGA-BASED LIFESTYLE INTERVENTION IS A NONINVASIVE EFFECTIVE TREATMENT METHOD TO CONTROL AND PREVENT CARDIAC RISK FACTORS IN CAD PATIENTS. YOGA HAS BEEN USED IN INDIA AS A THERAPEUTIC METHOD TO MANAGE HYPERTENSION AND OTHER CHRONIC DISORDERS AND IS FAST GAINING POPULARITY AS AN EFFECTIVE MEANS FOR THE ALLEVIATION OF STRESS, IMPROVEMENT OF FITNESS, AND ENHANCEMENT OF WELL-BEING. THIS STUDY AIMED TO DETERMINE THE FEASIBILITY OF INTRODUCING THE INTEGRATED APPROACH OF YOGA THERAPY (IAYT) IN A CARDIAC REHABILITATION CENTER IN INDIA AND UNDERSTAND ITS USEFULNESS IN IMPROVING THE CARDIAC FUNCTION AND MANAGING THE CARDIAC RISK FACTORS IN ACUTE MYOCARDIAL INFARCTION PATIENTS WITH LEFT VENTRICULAR DYSFUNCTION. METHODS AND DESIGN: CARDIAC PATIENTS WERE RANDOMIZED TO A YOGA-PRACTICING GROUP (N = 33) AND A CONTROL GROUP (N = 33). THE YOGA-PRACTICING GROUP WAS INSTRUCTED TO ATTEND THREE SUPERVISED IAYT CLASSES 3 DAYS PER WEEK FOR 12 WEEKS AT THE HOSPITAL YOGA CENTER. THE CONTROL GROUP RECEIVED STANDARD CARE THAT INCLUDED PHARMACOLOGIC TREATMENT AND THE INSTRUCTIONS OF THE CARDIOLOGIST. THE OUTCOME MEASURES WERE ASSESSED AT BASELINE (T1 = 0) AND COMPLETION (T2 = 3 MONTHS). THE PRIMARY OUTCOME MEASURE WAS THE LEFT VENTRICULAR EJECTION FRACTION (LVEF). RESULTS: THERE WAS NO STATISTICALLY SIGNIFICANT DIFFERENCE IN LVEF (U = 420.500, P VALUE = 0.218) BETWEEN THE TWO GROUPS. HOWEVER, THE YOGA-PRACTICING GROUP SHOWED SIGNIFICANT REDUCTION IN DEPRESSION (CARDIAC DEPRESSION SCALE [CDS], U = 71, P VALUE = 0.0), ANXIETY (HAMILTON ANXIETY RATING SCALE [HAM-A], U = 128, P VALUE = 0.0), AND A SIGNIFICANT INCREASE IN QUALITY OF LIFE (QOL) SCORES (DUKE ACTIVITY STATUS INDEX [DASI], U = 146, P VALUE = 0.0; AND METABOLIC EQUIVALENTS (METS), U = 136, P VALUE = 0.0) AT 3 MONTHS COMPARED TO CONTROL. OVERALL, THE CAD PATIENTS PRACTICING YOGA SHOWED A FAVORABLE PROFILE COMPARED TO CONTROL INDIVIDUALS ON CDS, HAM-A, DASI, AND MET OUTCOMES. CONTROL AND YOGA PRACTICING GROUPS DID NOT DIFFER SIGNIFICANTLY IN THE LIPID LEVELS. CONCLUSION: THIS STUDY INDICATED THAT THE INTEGRATION OF YOGA PRACTICE IN A CARDIAC REHABILITATION PROGRAM IS FEASIBLE AND HAS NO ADDED BENEFIT IN IMPROVING THE CARDIAC FUNCTION. HOWEVER, THE ADDITION OF YOGA TO CARDIAC REHABILITATION MAY BE BENEFICIAL IN REDUCING DEPRESSION AND ANXIETY AND IMPROVING QOL IN PATIENTS.	2020	

15 1328  37 HIGH-DENSITY LIPOPROTEIN CHOLESTEROL INCREASES FOLLOWING A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION: A NON-PHARMACOLOGICAL MODULATION. OBJECTIVES: THE OBJECTIVE OF THE STUDY WAS TO ASSESS THE EFFECT OF A BRIEF BUT COMPREHENSIVE YOGA-BASED LIFESTYLE INTERVENTION ON HIGH-DENSITY LIPOPROTEIN CHOLESTEROL (HDL-C). METHODS: THIS PROSPECTIVE INTERVENTIONAL STUDY WAS PERFORMED AT THE INTEGRAL HEALTH CLINIC (IHC), AN OUTPATIENT FACILITY AT ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, A TERTIARY HEALTH CARE CENTRE, CONDUCTING YOGA-BASED LIFESTYLE INTERVENTION PROGRAMMES FOR PREVENTION AND MANAGEMENT OF CHRONIC DISEASES. THE STUDY INCLUDED APPARENTLY HEALTHY NORMAL WEIGHT, OVERWEIGHT AND OBESE SUBJECTS WHO UNDERWENT A PRETESTED 10-DAY YOGA-BASED PROGRAMME INCLUDING ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), MEDITATION, GROUP DISCUSSIONS, LECTURES AND INDIVIDUALIZED ADVICE ON STRESS MANAGEMENT AND HEALTHY DIET. THE PRIMARY OUTCOME MEASURE WAS CHANGE IN SERUM HDL-C AT DAY 10 VERSUS DAY 0. RESULTS: 238 PARTICIPANTS (147 WOMEN, 91 MEN, 38.81+/-11.40 YEARS) WERE INCLUDED IN THE STUDY. THERE WAS A SIGNIFICANT INCREASE IN HDL-C LEVELS FROM BASELINE TO DAY 10 (42.93+/-5.00 VS 43.52+/-5.07 MG/DL, P = 0.043). NOTABLY, HDL-C WAS SIGNIFICANTLY IMPROVED IN THOSE FOR WHOM THE BASELINE HDL-C LEVELS WERE LOWER THAN THE RECOMMENDED VALUES. ALSO, THERE WAS A REDUCTION IN BLOOD PRESSURE, FASTING BLOOD GLUCOSE, AND IMPROVEMENT IN OTHER LIPID PROFILE VARIABLES. CONCLUSION: THIS YOGA-BASED LIFESTYLE INTERVENTION SIGNIFICANTLY INCREASED HDL-C LEVELS IN A SHORT DURATION OF 10 DAYS. THIS HAS ADDITIONAL CLINICAL RELEVANCE AS HDL-C IS SUGGESTED TO BE ONE OF THE STRONGEST STATISTICALLY INDEPENDENT PREDICTORS OF MAJOR CARDIOVASCULAR EVENTS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
16 2242  35 THE INFLUENCE OF PHYSICAL ACTIVITY AND YOGA ON CENTRAL ARTERIAL STIFFNESS. PURPOSE: CENTRAL ARTERIAL STIFFNESS IS AN ACCEPTED RISK FACTOR FOR CARDIOVASCULAR DISEASE. WHILE AEROBIC ACTIVITY IS ASSOCIATED WITH REDUCED STIFFNESS THE INFLUENCE OF PRACTICING YOGA IS UNKNOWN. THE AIMS OF THIS STUDY WERE TO: 1) EVALUATE ARTERIAL STIFFNESS IN MIDDLE-AGED ADULTS WHO REGULARLY PRACTICED YOGA, PERFORMED REGULAR EXERCISE, OR WERE INACTIVE, 2) EVALUATE THE REPRODUCIBILITY OF ARTERIAL STIFFNESS MEASURED IN THE LEFT AND RIGHT CAROTID ARTERY AND BY PULSE WAVE VELOCITY (PWV). METHODS: TWENTY SIX HEALTHY SUBJECTS (MALE AND FEMALE, 40-65 YRS OLD) WERE TESTED ON TWO SEPARATE DAYS. CAROTID ARTERY DISTENSIBILITY (DC) WAS MEASURED WITH ULTRASOUND. PHYSICAL ACTIVITY WAS DETERMINED BY QUESTIONNAIRE. RESULTS: YOGA AND AEROBIC SUBJECTS HAD SIMILAR PHYSICAL ACTIVITY LEVELS. YOGA AND AEROBIC GROUPS WERE NOT DIFFERENT IN EITHER DC (P = 0.26) OR PWV (P = 0.21). THE SEDENTARY GROUP HAD LOWER DC AND HIGHER PWV COMPARED TO THE AEROBIC AND YOGA GROUPS (BOTH, P < 0.001). STIFFNESS MEASURES WERE RELIABLE DAY TO DAY (COEFFICIENTS OF VARIATION APPROXIMATELY 2.5%) AND SIMILAR BETWEEN LEFT AND RIGHT ARTERIES (CV = 2.2%). CONCLUSION: PHYSICAL ACTIVITY WAS A STRONG PREDICTOR OF BOTH MEASURES OF ARTERIAL STIFFNESS, ALTHOUGH OTHER FACTORS SUCH AS NUTRITIONAL STATUS NEED TO BE ACCOUNTED FOR. AN INDEPENDENT EFFECT OF PRACTICING YOGA COULD NOT BE DETECTED. STIFFNESS MEASURES WERE REPRODUCIBLE AND LEFT AND RIGHT SIDES WERE CONSISTENT WITH EACH OTHER.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
17 2076  30 THE EFFECT OF BIKRAM YOGA ON ENDOTHELIAL FUNCTION IN YOUNG AND MIDDLE-AGED AND OLDER ADULTS. THE PURPOSE OF THIS INVESTIGATION WAS TO DETERMINE IF BIKRAM YOGA, A STYLE OF HEATED HATHA YOGA, WOULD IMPROVE ENDOTHELIAL FUNCTION IN YOUNG AND MIDDLE-AGED AND OLDER, HEALTHY ADULTS. THIS TRIAL WAS PERFORMED IN 36 YOUNG (N = 17) AND MIDDLE-AGED AND OLDER ADULTS (N = 19) WHO COMPLETED 3 WEEKLY BIKRAM YOGA CLASSES FOR 8 WEEKS. HEIGHT, BODY WEIGHT AND BODY COMPOSITION WERE DETERMINED AND ENDOTHELIAL FUNCTION WAS MEASURED NONINVASIVELY USING BRACHIAL ARTERY FLOW-MEDIATED DILATION (FMD) BEFORE AND AFTER THE INTERVENTION. NO CHANGES IN BODY WEIGHT, BMI OR BODY FAT PERCENTAGE OCCURRED AS A RESULT OF THE INTERVENTION IN EITHER GROUP. BRACHIAL ARTERY FMD WAS SIGNIFICANTLY INCREASED IN MIDDLE-AGED AND OLDER (P < 0.05) BUT NOT IN YOUNG ADULTS AS A RESULT OF THE INTERVENTION. THE RESULTS DEMONSTRATE THAT A RELATIVELY SHORT-TERM BIKRAM YOGA PRACTICE MIGHT SIGNIFICANTLY IMPROVE VASCULAR ENDOTHELIAL FUNCTION IN MIDDLE-AGED AND OLDER ADULTS. WHILE APPARENTLY HEALTHY INDIVIDUALS IN THIS STUDY EXPERIENCED NO ADVERSE EVENTS, THOSE WITH PREEXISTING CONDITIONS SHOULD TAKE CAUTION AND CONSULT WITH A PHYSICIAN PRIOR TO ENGAGING IN THIS STYLE OF YOGA.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
18  435  37 CARDIOPULMONARY AND METABOLIC EFFECTS OF YOGA IN HEALTHY VOLUNTEERS. BACKGROUND: YOGA THE SPIRITUAL UNION OF MIND WITH THE DIVINE INTELLIGENCE OF THE UNIVERSE AIMS TO LIBERATE A HUMAN BEING FROM CONFLICTS OF BODY-MIND DUALITY. BENEFICIAL CARDIOVASCULAR AND PULMONARY EFFECTS OF YOGA ARE IN PAR WITH AEROBIC EXERCISE, EVEN AMOUNTING TO REPLACE THE EXERCISE MODEL. WE CONDUCTED AN INTERVENTIONAL STUDY IN HEALTHY VOLUNTEERS, TO ANALYZE THE IMPACT OF SHORT-TERM YOGA TRAINING ON CARDIOVASCULAR, PULMONARY, AUTONOMIC FUNCTION TESTS, LIPID PROFILE, AND THYROID FUNCTION TESTS. MATERIALS AND METHODS: A SAMPLE OF FIFTY NEW RECRUITS ATTENDING THE DISTRICT YOGA CENTER WAS SUBJECT TO 75 MIN YOGA PRACTICE A DAY FOR 41 DAYS. BASAL VALUES OF CARDIOVASCULAR, PULMONARY, AUTONOMIC FUNCTION TESTS, LIPID PROFILE, AND THYROID FUNCTION TESTS WERE RECORDED BEFORE YOGA TRAINING AND WERE REASSESSED FOR POSTYOGA CHANGES AFTER 41 DAYS. RESULTS: AFTER YOGA PRACTICE THERE WAS A SIGNIFICANT REDUCTION IN THE RESTING HEART RATE, SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE, AND MEAN BLOOD PRESSURE OF THE PARTICIPANTS. EFFECTS ON AUTONOMIC FUNCTION TESTS WERE VARIABLE AND INCONCLUSIVE. THERE WAS A SIGNIFICANT INCREASE IN FORCED VITAL CAPACITY, FORCED EXPIRATORY VOLUME IN 1 S, AND PEAK EXPIRATORY FLOW RATE AFTER YOGA. A SIGNIFICANT REDUCTION IN BODY MASS INDEX WAS OBSERVED. EFFECTS ON METABOLIC PARAMETERS WERE PROMISING WITH A SIGNIFICANT REDUCTION IN FASTING BLOOD SUGAR LEVEL, SERUM TOTAL CHOLESTEROL, SERUM TRIGLYCERIDES SERUM LOW-DENSITY LIPOPROTEIN LEVELS, AND SIGNIFICANT INCREASE IN HIGH-DENSITY LIPOPROTEIN. THERE WAS NO SIGNIFICANT CHANGE IN THYROID FUNCTION TESTS AFTER YOGA. CONCLUSION: SHORT-TERM YOGA PRACTICE HAS NO EFFECT ON THYROID FUNCTIONS. YOGA PRACTICE WAS FOUND BENEFICIAL IN MAINTAINING PHYSIOLOGICAL MILIEU PERTAINING TO CARDIOVASCULAR AND OTHER METABOLIC PARAMETERS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
19  679  35 EFFECT OF A YOGA PROGRAM ON GLUCOSE METABOLISM AND BLOOD LIPID LEVELS IN ADOLESCENT GIRLS WITH POLYCYSTIC OVARY SYNDROME. OBJECTIVE: TO ASSESS THE EFFICACY OF YOGA THERAPY ON GLUCOSE METABOLISM AND BLOOD LIPID VALUES IN ADOLESCENT GIRLS WITH POLYCYSTIC OVARY SYNDROME (PCOS). METHODS: A PROSPECTIVE, RANDOMIZED, INTERVENTIONAL CONTROLLED TRIAL RECRUITED 90 ADOLESCENTS AGED BETWEEN 15 AND 18 YEARS WHO MET THE ROTTERDAM CRITERIA FOR PCOS. A YOGA GROUP PRACTICED SURYANAMASKARA, ASANAS, PRANAYAMA, AND MEDITATION 1 HOUR PER DAY EACH DAY FOR 12 WEEKS WHILE ANOTHER GROUP PRACTICED CONVENTIONAL PHYSICAL EXERCISES. THE MANN-WHITNEY U TEST WAS USED TO COMPARE SCORE CHANGES BETWEEN THE 2 GROUPS. RESULTS: THE CHANGES IN FASTING INSULIN, FASTING BLOOD GLUCOSE, AND HOMEOSTASIS MODEL ASSESSMENT OF INSULIN RESISTANCE WERE SIGNIFICANTLY DIFFERENT IN THE 2 GROUPS (P<0.05). EXCEPT FOR HIGH-DENSITY LIPOPROTEIN CHOLESTEROL, THE CHANGES IN BLOOD LIPID VALUES WERE ALSO SIGNIFICANTLY DIFFERENT (P<0.05). THE CHANGES IN BODY MASS INDEX, WAIST CIRCUMFERENCE, HIP CIRCUMFERENCE, AND WAIST-TO-HIP RATIO, HOWEVER, WERE NOT SIGNIFICANTLY DIFFERENT (P>0.05). CONCLUSION: YOGA WAS FOUND TO BE MORE EFFECTIVE THAN CONVENTIONAL PHYSICAL EXERCISES IN IMPROVING GLUCOSE, LIPID, AND INSULIN VALUES, INCLUDING INSULIN RESISTANCE VALUES, IN ADOLESCENT GIRLS WITH PCOS INDEPENDENT OF ANTHROPOMETRIC CHANGES. CENTRAL TRIAL REGISTRY OF INDIA NO.: REFCTRI-2008 000291.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
20 2153  25 THE EFFECTS OF SUDARSHAN KRIYA YOGA ON SOME PHYSIOLOGICAL AND BIOCHEMICAL PARAMETERS IN MILD HYPERTENSIVE PATIENTS. AN OPEN LABEL INTERVENTION STUDY WAS UNDERTAKEN ON 26 MILD HYPERTENSIVES AND 26 APPARENTLY HEALTHY ADULTS (30-60 Y), FOR THE EFFECT OF SUDARSHAN KRIYA YOGA PRACTICE FOR TWO MONTHS AS COMPLEMENTARY THERAPY. IN THE HYPERTENSIVES, THERE WAS A SIGNIFICANT DECREASE IN DIASTOLIC BLOOD PRESSURE (P < 0.01), SERUM UREA (P < 0.01) AND PLASMA MDA (MALONDIALDEHYDE ADDUCTS) AS OXIDATIVE STRESS MARKER (P < 0.05). OTHER PARAMETERS; VIZ.; PLASMA LEVELS OF CHOLESTEROL, TRIGLYCERIDES, GLUCOSE, DID NOT CHANGE SIGNIFICANTLY (P > 0.1). THE PATTERN OF CHANGE IN MOST OF THE STUDY PARAMETERS WAS SUCH THAT VALUES ABOVE NORMAL RANGE WERE LOWERED BUT VALUES WITHIN NORMAL RANGE WERE UNALTERED. THE ACTION OF YOGA ON DIASTOLIC BLOOD PRESSURE, MALONDIALDEHYDE ADDUCTS AND KIDNEY FUNCTION IN HYPERTENSIVES WAS OF COUNTERACTIVE NATURE AND FELT TO BE DISTINCTLY DIFFERENT THAN THE EFFECT OF DRUGS.	2011