1 1706 98 PATTERN OF BREATHING AND VENTILATORY RESPONSE TO CO2 IN SUBJECTS PRACTICING HATHA-YOGA. WE STUDIED EIGHT BELGIAN SUBJECTS WELL ADVANCED IN THE PRACTICE OF HATHA-YOGA AND COMPARED THEM WITH EIGHT SEX-, AGE-, AND HEIGHT-MATCHED CONTROL SUBJECTS. PRACTICE OF YOGA (RANGE 4-12 YR) INVOLVES CONTROL OF POSTURE AND MANIPULATION OF BREATHING, INCLUDING SLOW NEAR-VITAL CAPACITY MANEUVERS ACCOMPANIED BY APNEA AT END INSPIRATION AND END EXPIRATION. AVERAGE VALUES FOR THE YOGA AND THE CONTROL GROUP (IN PARENTHESES) ARE AS FOLLOWS: VENTILATION (VE) 5.53 1 X MIN-1 (7.07); TIDAL VOLUME (VT), 1.03 LITERS (0.56); RATE OF BREATHING, 5.5 MIN-1 (13.4); END-TIDAL PCO2, 39.0 TORR (35.3). ALL DIFFERENCES ARE SIGNIFICANT (P LESS THAN 0.05). VENTILATORY RESPONSE TO CO2 (REBREATHING TECHNIQUE) WAS SIGNIFICANTLY LOWER IN THE YOGA GROUP (P LESS THAN 0.01). THE REGRESSION RELATING VE TO VT DURING REBREATHING OF CO2 WAS VE = 8.1 (VT - 0.23) FOR THE YOGA GROUP AND VE = 15.8 (VT - 0.16) FOR THE CONTROL GROUP (P LESS THAN 0.005). WE ATTRIBUTE THESE CHANGES TO CHRONIC MANIPULATION OF RESPIRATION.	1981	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
2 1118 23 EFFICACY OF AN EIGHT-WEEK YOGA INTERVENTION ON SYMPTOMS OF RESTLESS LEGS SYNDROME (RLS): A PILOT STUDY. BACKGROUND: RESTLESS LEGS SYNDROME (RLS) IS A COMMON AND HIGHLY BURDENSOME SLEEP DISORDER. WHILE RELAXATION THERAPIES, INCLUDING YOGA, ARE OFTEN RECOMMENDED FOR RLS MANAGEMENT, RIGOROUS SUPPORTING RESEARCH IS SPARSE. THE GOAL OF THIS PRELIMINARY STUDY WAS TO ASSESS THE EFFECTS OF YOGA ON RLS SYMPTOMS AND RELATED OUTCOMES IN WOMEN WITH RLS. METHODS: PARTICIPANTS WERE 13 NONSMOKING WOMEN WITH MODERATE TO SEVERE RLS, WHO DID NOT HAVE DIABETES, SLEEP APNEA, OR OTHER SERIOUS CONCOMITANT CHRONIC CONDITIONS, AND WHO WERE NOT PREGNANT. THE INTERVENTION WAS A GENTLE, 8-WEEK IYENGAR YOGA PROGRAM. CORE OUTCOMES ASSESSED PRE- AND POST-TREATMENT WERE RLS SYMPTOMS AND SYMPTOM SEVERITY (INTERNATIONAL RLS SCALE [IRLS] AND RLS ORDINAL SCALE), SLEEP QUALITY (MEDICAL OUTCOMES STUDY SLEEP SCALE), MOOD (PROFILE OF MOOD STATES), AND PERCEIVED STRESS (PERCEIVED STRESS SCALE). PARTICIPANTS ALSO COMPLETED YOGA LOGS AND A BRIEF EXIT QUESTIONNAIRE REGARDING THEIR EXPERIENCE WITH THE STUDY. RESULTS: TEN (10) WOMEN, AGED 32-66 YEARS, COMPLETED THE STUDY. PARTICIPANTS ATTENDED AN AVERAGE 13.4+/-0.5 (OF 16 POSSIBLE) CLASSES, AND COMPLETED A MEAN OF 4.1+/-0.3 (OF 5 POSSIBLE) HOMEWORK SESSIONS/WEEK. AT FOLLOW-UP, PARTICIPANTS DEMONSTRATED STRIKING REDUCTIONS IN RLS SYMPTOMS AND SYMPTOM SEVERITY, WITH SYMPTOMS DECREASING TO MINIMAL/MILD IN ALL BUT 1 WOMAN AND NO PARTICIPANT SCORING IN THE SEVERE RANGE BY WEEK 8. EFFECT SIZES (COHEN'S D) WERE LARGE: 1.6 FOR IRLS TOTAL, AND 2.2 FOR RLS ORDINAL SCALE. IRLS SCORES DECLINED SIGNIFICANTLY WITH INCREASING MINUTES OF HOMEWORK PRACTICE PER SESSION (R=0.70, P=0.025) AND TOTAL HOMEWORK MINUTES (R=0.64, P<0.05), SUGGESTING A POSSIBLE DOSE-RESPONSE RELATION. PARTICIPANTS ALSO SHOWED SIGNIFICANT IMPROVEMENTS IN SLEEP, PERCEIVED STRESS, AND MOOD (ALL P'S</=0.02), WITH EFFECT SIZES RANGING FROM 1.0 TO 1.6. CONCLUSIONS: THESE PRELIMINARY FINDINGS SUGGEST THAT YOGA MAY BE EFFECTIVE IN ATTENUATING RLS SYMPTOMS AND SYMPTOM SEVERITY, REDUCING PERCEIVED STRESS, AND IMPROVING SLEEP AND MOOD IN WOMEN WITH RLS.	2013	
                                                                                                                                                                                                                                                                                                                                                                       
3  332 22 APPLICATION OF STANDARDISED YOGA PROTOCOLS AS THE BASIS OF PHYSIOTHERAPY RECOMMENDATION IN TREATMENT OF SLEEP APNEAS: MOVING BEYOND PRANAYAMAS. YOGA IS AN ANCIENT INDIAN PRACTICE OF MENTAL AND PHYSICAL EXERCISES (SYN: ASANAS), POSTURES (SYN: MUDRAS), MOVEMENTS AND BREATHING TECHNIQUES WHICH SUSTAIN HEALTHY LIVING OF THE BODY AND THE MIND. IT INCORPORATES VARIOUS EXERCISES OF BREATHING, OROPHARYNGEAL STRUCTURES AND FACIAL EXPRESSIONS, THE PHYSIOLOGY AND EFFECT OF WHICH ARE COMPARABLE TO INTERNATIONAL PHYSIOTHERAPY RECOMMENDATIONS IN TREATMENT OF OBSTRUCTIVE SLEEP APNEA (OSA) I.E. TO PRESERVE UPPER AIRWAY PATENCY BY MAINTAINING AIRWAY DILATOR MUSCLE TONE. PRELIMINARY RESULTS SHOW THAT YOGA CAN BE AN EFFECTIVE AND CONSTRUCTIVE ALTERNATIVE TO PHYSIOTHERAPY FOR SLEEP APNEA AND SNORING PATIENTS. TO COMPARE THE PHYSIOTHERAPY RECOMMENDATIONS IN SNORING PATIENTS WITH VARIOUS YOGA EXERCISES POSTURES. TO DETERMINE THE EFFICACY OF YOGA IN TREATMENT OF SLEEP APNEA. TO FORMULATE A STANDARDIZED YOGA PROTOCOL FOR UNIVERSAL USAGE IN SLEEP APNEA. WE STUDIED THE AVAILABLE LITERATURE ON PHYSIOTHERAPY RECOMMENDATIONS FOR OSA AND YOGA ASANAS INVOLVING THE NASAL, OROPHARYNX AND FACIAL STRUCTURES AND PERCEIVED A NOTEWORTHY SIMILARITY IN PHYSIOLOGICAL BASIS OF BOTH. A SET OF THESE YOGASANAS WERE PUT TOGETHER AND PATIENTS PRESENTING WITH SNORING AND DIAGNOSED WITH MILD TO MODERATE SLEEP APNEA WERE PRESENTED AND ENCOURAGED TO PERFORM THE STANDARDIZED SET OF YOGA EXERCISES FOR A PERIOD OF 3 MONTHS. A TOTAL OF 23 PATIENTS WERE RECOMMENDED YOGA PROTOCOLS AS INITIAL FORM OF TREATMENT IN SNORING AND MILD TO MODERATE SLEEP APNEA. CLINICAL AND STATISTICALLY SIGNIFICANT IMPROVEMENT GAUZED BY RECOMMENDED SCORE CHART WAS DISCERNED IN MAJORITY OF SUBJECTS. THE RESULTS WERE COMPARABLE TO THE EFFICACY OF EXISTING PHYSIOTHERAPY REGIMEN PUBLISHED IN INTERNATIONAL LITERATURE. THE BENEFITS OF YOGA IN SLEEP DISORDERS GO BEYOND THE SCOPE OF MEASURED OUTCOMES. STANDARDIZING THE PROTOCOLS FOR YOGA IN TREATMENT FOR SNORING AND SLEEP APNEA IS THE NEED OF THE HOUR. FURTHER STUDIES ON EFFICACY OF YOGA NEED TO BE PERFORMED TO UNDERSTAND ITS FULL REALM OF POTENTIAL.	2019	
                                                                                                                                                                                                                                                                                                                                                               
4  663 23 EFFECT OF 6 MONTHS INTENSE YOGA PRACTICE ON LIPID PROFILE, THYROXINE MEDICATION AND SERUM TSH LEVEL IN WOMEN SUFFERING FROM HYPOTHYROIDISM: A PILOT STUDY. BACKGROUND: A SIGNIFICANT NUMBER OF WOMEN IN INDIA ARE SUFFERING FROM HYPOTHYROIDISM. HYPOTHYROIDISM IS CHARACTERIZED BY ELEVATED LIPID PROFILES AND THYROID STIMULATION HORMONE (TSH). IT LEADS MANY COMORBID CONDITIONS SUCH AS CORONARY ARTERY DISEASE, OBESITY, DEPRESSION, OSTEOPOROSIS, SLEEP APNEA, AND ETC. YOGA IS PROVEN TO BE EFFECTIVE IN REDUCING WEIGHT, DYSLIPIDEMIA, DEPRESSION AND IT BRINGS THE BALANCE IN AUTONOMOUS NERVOUS SYSTEM. WE AIMED TO STUDY THE EFFECT OF 6 MONTHS YOGA PRACTICE ON LIPID PROFILE, THYROXINE REQUIREMENT AND SERUM TSH IN WOMEN SUFFERING FROM HYPOTHYROIDISM. METHODS: TWENTY-TWO HOUSEHOLD WOMEN SUFFERING FROM HYPOTHYROIDISM BETWEEN THE AGE RANGE OF 30 AND 40 (MEAN+/-SD; 36.7+/-3.2) YEARS, WITH AVERAGE 4+/-1.12-YEAR HISTORY OF HYPOTHYROIDISM WERE INCLUDED IN THIS STUDY. SUBJECTS WITH KNOWN CARDIAC ISSUES, HYPERTENSION, HISTORY, RECENT SURGERY, SLIP DISC AND LOW BACK PAIN WERE EXCLUDED FROM THIS STUDY. NONE OF THE SUBJECTS WERE ON ANY OTHER MEDICATION EXCEPT THYROXINE WHICH WAS KEPT DURING THE INTERVENTION PHAGE (MEAN 65.78+/-22.74 MCG). ALL THE SUBJECTS UNDERWENT 6 MONTHS OF YOGA PRACTICE 1 H DAILY FOR 4 DAYS A WEEK. LIPID PROFILE, THYROXINE DOSAGE AND SERUM TSH LEVEL WERE ASSESSED BEFORE AND AFTER INTERVENTION. DATA WAS ANALYZED USING PAIRED SAMPLE T TEST & WILCOXON'S SIGNED RANK TEST. RESULTS: THE PAIRED SAMPLE T-TEST SHOWED SIGNIFICANT REDUCTION IN TOTAL CHOLESTEROL (P=0.006; -8.99%), LOW-DENSITY LIPOPROTEIN (LDL) (P=0.002; -9.81%) AND TRIGLYCERIDES (P=0.013; -7.6%), AND THERE WAS A SIGNIFICANT IMPROVEMENT IN HIGH-DENSITY LIPOPROTEIN (HDL) (P=0.02; +9.65%) ALONG WITH NONSIGNIFICANT REDUCTION IN TSH LEVEL (P=0.452; -9.72%). WILCOXON SIGNED-RANK TEST SHOWED SIGNIFICANT REDUCTION IN THYROXINE MEDICATION SCORE (P=0.029; -15.30%) FROM. CONCLUSION: 6 MONTHS PRACTICE OF YOGA MAY HELP IN IMPROVING CHOLESTEROL LEVEL, SERUM TSH, MAY ALSO HELP IN REDUCING THE THYROXINE REQUIREMENT IN FEMALE PATIENTS SUFFERING FROM HYPOTHYROIDISM. HOWEVER, FURTHER RANDOMIZED CONTROLLED STUDIES NEED TO BE CONDUCTED TO CONFIRM THE PRESENT FINDING.	2016	
                                                                                                                                                                                                                                                                             
5  945 19 EFFECTS OF A 12-WEEK YOGA VERSUS A 12-WEEK EDUCATIONAL FILM INTERVENTION ON SYMPTOMS OF RESTLESS LEGS SYNDROME AND RELATED OUTCOMES: AN EXPLORATORY RANDOMIZED CONTROLLED TRIAL. STUDY OBJECTIVES: TO ASSESS THE EFFECTS OF A YOGA VERSUS EDUCATIONAL FILM (EF) PROGRAM ON RESTLESS LEGS SYNDROME (RLS) SYMPTOMS AND RELATED OUTCOMES IN ADULTS WITH RLS. METHODS: FORTY-ONE COMMUNITY-DWELLING, AMBULATORY NONPREGNANT ADULTS WITH MODERATE TO SEVERE RLS WERE RANDOMIZED TO A 12-WEEK YOGA (N = 19) OR EF PROGRAM (N = 22). IN ADDITION TO ATTENDING CLASSES, ALL PARTICIPANTS COMPLETED PRACTICE/TREATMENT LOGS. YOGA GROUP PARTICIPANTS WERE ASKED TO PRACTICE AT HOME 30 MINUTES PER DAY ON NONCLASS DAYS; EF PARTICIPANTS WERE INSTRUCTED TO RECORD ANY RLS TREATMENTS USED ON THEIR DAILY LOGS. CORE OUTCOMES ASSESSED PRETREATMENT AND POSTTREATMENT WERE RLS SYMPTOMS AND SYMPTOM SEVERITY (INTERNATIONAL RLS STUDY GROUP SCALE (IRLS) AND RLS ORDINAL SCALE), SLEEP QUALITY, MOOD, PERCEIVED STRESS, AND QUALITY OF LIFE (QOL). RESULTS: THIRTY ADULTS (13 YOGA, 17 EF), AGED 24 TO 73 (MEAN = 50.4 +/- 2.4 YEARS), COMPLETED THE 12-WEEK STUDY (78% FEMALE, 80.5% WHITE). POST-INTERVENTION, BOTH GROUPS SHOWED SIGNIFICANT IMPROVEMENT IN RLS SYMPTOMS AND SEVERITY, PERCEIVED STRESS, MOOD, AND QOL-MENTAL HEALTH (P </= .04). RELATIVE TO THE EF GROUP, YOGA PARTICIPANTS DEMONSTRATED SIGNIFICANTLY GREATER REDUCTIONS IN RLS SYMPTOMS AND SYMPTOM SEVERITY (P </= .01), AND GREATER IMPROVEMENTS IN PERCEIVED STRESS AND MOOD (P </= .04), AS WELL AS SLEEP QUALITY (P = .09); RLS SYMPTOMS DECREASED TO MINIMAL/MILD IN 77% OF YOGA GROUP PARTICIPANTS, WITH NONE SCORING IN THE SEVERE RANGE BY WEEK 12, VERSUS 24% AND 12%, RESPECTIVELY, IN EF PARTICIPANTS. IN THE YOGA GROUP, IRLS AND RLS SEVERITY SCORES DECLINED WITH INCREASING MINUTES OF HOMEWORK PRACTICE (R = .7, P = .009 AND R = .6, P = .03, RESPECTIVELY), SUGGESTING A POSSIBLE DOSE-RESPONSE RELATIONSHIP. CONCLUSIONS: FINDINGS OF THIS EXPLORATORY RCT SUGGEST THAT YOGA MAY BE EFFECTIVE IN REDUCING RLS SYMPTOMS AND SYMPTOM SEVERITY, DECREASING PERCEIVED STRESS, AND IMPROVING MOOD AND SLEEP IN ADULTS WITH RLS. CLINICAL TRIAL REGISTRATION: REGISTRY: CLINICALTRIALS.GOV; TITLE: YOGA VS. EDUCATION FOR RESTLESS LEGS: A FEASIBILITY STUDY; IDENTIFIER: NCT03570515; URL: HTTPS://CLINICALTRIALS.GOV/CT2/SHOW/NCT03570515.	2020	
                                                                                                                                                                             
6 1374 22 IMPACT OF AN INTEGRATED YOGA THERAPY PROTOCOL ON INSULIN RESISTANCE AND GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. OBJECTIVE: DIABETES MELLITUS (DM), CHARACTERIZED BY CHRONIC HYPERGLYCEMIA, IS ATTRIBUTED TO RELATIVE INSULIN DEFICIENCY OR RESISTANCE, OR BOTH. STUDIES HAVE SHOWN THAT YOGA CAN MODULATE PARAMETERS OF INSULIN RESISTANCE. THE PRESENT STUDY EXPLORED THE POSSIBLE BENEFICIAL EFFECTS OF INTEGRATED YOGA THERAPY WITH REFERENCE TO GLYCEMIC CONTROL AND INSULIN RESISTANCE (IR) IN INDIVIDUALS WITH DIABETES MAINTAINED ON STANDARD ORAL MEDICAL CARE WITH YOGA THERAPY, COMPARED TO THOSE ON STANDARD ORAL MEDICAL CARE ALONE. METHODS: IN THIS STUDY, THE SUBJECTS ON YOGA INTERVENTION COMPRISED 35 TYPE 2 DIABETICS, AND AN EQUAL NUMBER OF VOLUNTEERS CONSTITUTED THE CONTROL GROUP. SUBJECTS RANGED IN AGE FROM 30 TO 70 YEARS, WITH HEMOGLOBIN A1C (HBA1C) TEST MORE THAN 7%, AND WERE MAINTAINED ON DIABETIC DIET AND ORAL HYPOGLYCEMIC AGENTS. BLOOD SAMPLES WERE DRAWN PRIOR TO AND AFTER 120 DAYS OF INTEGRATED YOGA THERAPY INTERVENTION. FASTING BLOOD GLUCOSE (FBG), POST-PRANDIAL BLOOD GLUCOSE (PPBG), HBA1C, INSULIN, AND LIPID PROFILE WERE ASSESSED IN BOTH THE INTERVENTION AND CONTROL GROUPS. RESULTS: THE INTERVENTION GROUP REVEALED SIGNIFICANT IMPROVEMENTS IN BODY MASS INDEX (BMI) (0.7 KG/M(2) MEDIAN DECREASE; P=0.001), FBG (20 MG/DL MEDIAN DECREASE; P<0.001), PPBG (33 MG/DL MEDIAN DECREASE; P<0.001), HBA1C (0.4% MEDIAN DECREASE; P<0.001), HOMEOSTATIC MODEL ASSESSMENT FOR INSULIN RESISTANCE (HOMA-IR) (1.2 MEDIAN DECREASE; P<0.001), CHOLESTEROL (13 MG/DL MEDIAN DECREASE, P=0.006), TRIACYLGLYCEROL (22 MG/DL MEDIAN DECREASE; P=0.027), LOW-DENSITY LIPOPROTEIN (6 MG/DL MEDIAN DECREASE; P=0.004), AND VERY-LOW-DENSITY LIPOPROTEIN LEVELS (4 MG/DL MEDIAN DECREASE; P=0.032). INCREASES IN HIGH-DENSITY LIPOPROTEIN AFTER 120 DAYS WERE NOT SIGNIFICANT (6 MG/DL MEDIAN INCREASE; P=0.15). HOWEVER, WHEN COMPARED TO CHANGES OBSERVED IN PATIENTS IN THE CONTROL GROUP, ALL THESE IMPROVEMENTS PROVED TO BE SIGNIFICANT. CONCLUSION: ADMINISTRATION OF INTEGRATED YOGA THERAPY TO INDIVIDUALS WITH DIABETES LEADS TO A SIGNIFICANT IMPROVEMENT IN GLYCEMIC CONTROL, INSULIN RESISTANCE, AND KEY BIOCHEMICAL PARAMETERS.	2022	
                                                                                                                                                                                                                                                                                          
7 2132 14 THE EFFECTS OF A GENTLE YOGA PROGRAM ON SLEEP, MOOD, AND BLOOD PRESSURE IN OLDER WOMEN WITH RESTLESS LEGS SYNDROME (RLS): A PRELIMINARY RANDOMIZED CONTROLLED TRIAL. OBJECTIVE. TO EXAMINE THE EFFECTS OF YOGA VERSUS AN EDUCATIONAL FILM PROGRAM ON SLEEP, MOOD, PERCEIVED STRESS, AND SYMPATHETIC ACTIVATION IN OLDER WOMEN WITH RLS. METHODS. PARTICIPANTS WERE DRAWN FROM A LARGER TRIAL REGARDING THE EFFECTS OF YOGA ON CARDIOVASCULAR DISEASE RISK PROFILES IN OVERWEIGHT, SEDENTARY POSTMENOPAUSAL WOMEN. SEVENTY-FIVE WOMEN WERE RANDOMIZED TO RECEIVE EITHER AN 8-WEEK YOGA (N = 38) OR EDUCATIONAL FILM (N = 37) PROGRAM. ALL 75 PARTICIPANTS COMPLETED AN RLS SCREENING QUESTIONNAIRE. THE 20 WOMEN WHO MET ALL FOUR DIAGNOSTIC CRITERIA FOR RLS (N = 10 YOGA, 10 FILM GROUP) COMPRISED THE POPULATION FOR THIS NESTED STUDY. MAIN OUTCOMES ASSESSED PRE- AND POST-TREATMENT INCLUDED: SLEEP (PITTSBURGH SLEEP QUALITY INDEX), STRESS (PERCEIVED STRESS SCALE), MOOD (PROFILE OF MOOD STATES, STATE-TRAIT ANXIETY INVENTORY), BLOOD PRESSURE, AND HEART RATE. RESULTS. THE YOGA GROUP DEMONSTRATED SIGNIFICANTLY GREATER IMPROVEMENTS THAN CONTROLS IN MULTIPLE DOMAINS OF SLEEP QUALITY AND MOOD, AND SIGNIFICANTLY GREATER REDUCTIONS IN INSOMNIA PREVALENCE, ANXIETY, PERCEIVED STRESS, AND BLOOD PRESSURE (ALL P'S</=0.05). ADJUSTED INTERGROUP EFFECT SIZES FOR PSYCHOSOCIAL VARIABLES WERE LARGE, RANGING FROM 1.9 FOR STATE ANXIETY TO 2.6 FOR SLEEP QUALITY. CONCLUSIONS. THESE PRELIMINARY FINDINGS SUGGEST YOGA MAY OFFER AN EFFECTIVE INTERVENTION FOR IMPROVING SLEEP, MOOD, PERCEIVED STRESS, AND BLOOD PRESSURE IN OLDER WOMEN WITH RLS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
8  435 19 CARDIOPULMONARY AND METABOLIC EFFECTS OF YOGA IN HEALTHY VOLUNTEERS. BACKGROUND: YOGA THE SPIRITUAL UNION OF MIND WITH THE DIVINE INTELLIGENCE OF THE UNIVERSE AIMS TO LIBERATE A HUMAN BEING FROM CONFLICTS OF BODY-MIND DUALITY. BENEFICIAL CARDIOVASCULAR AND PULMONARY EFFECTS OF YOGA ARE IN PAR WITH AEROBIC EXERCISE, EVEN AMOUNTING TO REPLACE THE EXERCISE MODEL. WE CONDUCTED AN INTERVENTIONAL STUDY IN HEALTHY VOLUNTEERS, TO ANALYZE THE IMPACT OF SHORT-TERM YOGA TRAINING ON CARDIOVASCULAR, PULMONARY, AUTONOMIC FUNCTION TESTS, LIPID PROFILE, AND THYROID FUNCTION TESTS. MATERIALS AND METHODS: A SAMPLE OF FIFTY NEW RECRUITS ATTENDING THE DISTRICT YOGA CENTER WAS SUBJECT TO 75 MIN YOGA PRACTICE A DAY FOR 41 DAYS. BASAL VALUES OF CARDIOVASCULAR, PULMONARY, AUTONOMIC FUNCTION TESTS, LIPID PROFILE, AND THYROID FUNCTION TESTS WERE RECORDED BEFORE YOGA TRAINING AND WERE REASSESSED FOR POSTYOGA CHANGES AFTER 41 DAYS. RESULTS: AFTER YOGA PRACTICE THERE WAS A SIGNIFICANT REDUCTION IN THE RESTING HEART RATE, SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE, AND MEAN BLOOD PRESSURE OF THE PARTICIPANTS. EFFECTS ON AUTONOMIC FUNCTION TESTS WERE VARIABLE AND INCONCLUSIVE. THERE WAS A SIGNIFICANT INCREASE IN FORCED VITAL CAPACITY, FORCED EXPIRATORY VOLUME IN 1 S, AND PEAK EXPIRATORY FLOW RATE AFTER YOGA. A SIGNIFICANT REDUCTION IN BODY MASS INDEX WAS OBSERVED. EFFECTS ON METABOLIC PARAMETERS WERE PROMISING WITH A SIGNIFICANT REDUCTION IN FASTING BLOOD SUGAR LEVEL, SERUM TOTAL CHOLESTEROL, SERUM TRIGLYCERIDES SERUM LOW-DENSITY LIPOPROTEIN LEVELS, AND SIGNIFICANT INCREASE IN HIGH-DENSITY LIPOPROTEIN. THERE WAS NO SIGNIFICANT CHANGE IN THYROID FUNCTION TESTS AFTER YOGA. CONCLUSION: SHORT-TERM YOGA PRACTICE HAS NO EFFECT ON THYROID FUNCTIONS. YOGA PRACTICE WAS FOUND BENEFICIAL IN MAINTAINING PHYSIOLOGICAL MILIEU PERTAINING TO CARDIOVASCULAR AND OTHER METABOLIC PARAMETERS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
9  985 27 EFFECTS OF HATHA YOGA AND OMKAR MEDITATION ON CARDIORESPIRATORY PERFORMANCE, PSYCHOLOGIC PROFILE, AND MELATONIN SECRETION. OBJECTIVES: TO EVALUATE EFFECTS OF HATHA YOGA AND OMKAR MEDITATION ON CARDIORESPIRATORY PERFORMANCE, PSYCHOLOGIC PROFILE, AND MELATONIN SECRETION. SUBJECTS AND METHODS: THIRTY HEALTHY MEN IN THE AGE GROUP OF 25-35 YEARS VOLUNTEERED FOR THE STUDY. THEY WERE RANDOMLY DIVIDED IN TWO GROUPS OF 15 EACH. GROUP 1 SUBJECTS SERVED AS CONTROLS AND PERFORMED BODY FLEXIBILITY EXERCISES FOR 40 MINUTES AND SLOW RUNNING FOR 20 MINUTES DURING MORNING HOURS AND PLAYED GAMES FOR 60 MINUTES DURING EVENING HOURS DAILY FOR 3 MONTHS. GROUP 2 SUBJECTS PRACTICED SELECTED YOGIC ASANAS (POSTURES) FOR 45 MINUTES AND PRANAYAMA FOR 15 MINUTES DURING THE MORNING, WHEREAS DURING THE EVENING HOURS THESE SUBJECTS PERFORMED PREPARATORY YOGIC POSTURES FOR 15 MINUTES, PRANAYAMA FOR 15 MINUTES, AND MEDITATION FOR 30 MINUTES DAILY, FOR 3 MONTHS. ORTHOSTATIC TOLERANCE, HEART RATE, BLOOD PRESSURE, RESPIRATORY RATE, DYNAMIC LUNG FUNCTION (SUCH AS FORCED VITAL CAPACITY, FORCED EXPIRATORY VOLUME IN 1 SECOND, FORCED EXPIRATORY VOLUME PERCENTAGE, PEAK EXPIRATORY FLOW RATE, AND MAXIMUM VOLUNTARY VENTILATION), AND PSYCHOLOGIC PROFILE WERE MEASURED BEFORE AND AFTER 3 MONTHS OF YOGIC PRACTICES. SERIAL BLOOD SAMPLES WERE DRAWN AT VARIOUS TIME INTERVALS TO STUDY EFFECTS OF THESE YOGIC PRACTICES AND OMKAR MEDITATION ON MELATONIN LEVELS. RESULTS: YOGIC PRACTICES FOR 3 MONTHS RESULTED IN AN IMPROVEMENT IN CARDIORESPIRATORY PERFORMANCE AND PSYCHOLOGIC PROFILE. THE PLASMA MELATONIN ALSO SHOWED AN INCREASE AFTER THREE MONTHS OF YOGIC PRACTICES. THE SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE, MEAN ARTERIAL PRESSURE, AND ORTHOSTATIC TOLERANCE DID NOT SHOW ANY SIGNIFICANT CORRELATION WITH PLASMA MELATONIN. HOWEVER, THE MAXIMUM NIGHT TIME MELATONIN LEVELS IN YOGA GROUP SHOWED A SIGNIFICANT CORRELATION (R = 0.71, P < 0.05) WITH WELL-BEING SCORE. CONCLUSION: THESE OBSERVATIONS SUGGEST THAT YOGIC PRACTICES CAN BE USED AS PSYCHOPHYSIOLOGIC STIMULI TO INCREASE ENDOGENOUS SECRETION OF MELATONIN, WHICH, IN TURN, MIGHT BE RESPONSIBLE FOR IMPROVED SENSE OF WELL-BEING.	2004	
                                                                                                                                                                                                                                                                                                                                                 
10  959 16 EFFECTS OF A YOGA INTERVENTION ON LIPID PROFILES OF DIABETES PATIENTS WITH DYSLIPIDEMIA. OBJECTIVE: THE PRESENT STUDY WAS CONDUCTED TO ASSESS THE EFFECTIVENESS OF YOGA IN THE MANAGEMENT OF DYSLIPIDEMIA IN PATIENTS OF TYPE 2 DIABETES MELLITUS. METHODS: THIS RANDOMIZED PARALLEL STUDY WAS CARRIED OUT IN MEDICAL COLLEGE TRIVANDRUM, KERALA, INDIA. HUNDRED TYPE 2 DIABETICS WITH DYSLIPIDEMIA WERE RANDOMIZED INTO CONTROL AND YOGA GROUPS. THE CONTROL GROUP WAS PRESCRIBED ORAL HYPOGLYCEMIC DRUGS. THE YOGA GROUP PRACTICED YOGA DAILY FOR 1 H DURATION ALONG WITH ORAL HYPOGLYCEMIC DRUGS FOR 3 MONTHS. THE LIPID PROFILES OF BOTH THE GROUPS WERE COMPARED AT THE START AND AT THE END OF 3 MONTHS. RESULTS: AFTER INTERVENTION WITH YOGA FOR A PERIOD OF 3 MONTHS THE STUDY GROUP SHOWED A DECREASE IN TOTAL CHOLESTEROL, TRIGLYCERIDES AND LDL, WITH AN IMPROVEMENT IN HDL. CONCLUSION: YOGA, BEING A LIFESTYLE INCORPORATING EXERCISE AND STRESS MANAGEMENT TRAINING, TARGETS THE ELEVATED LIPID LEVELS IN PATIENTS WITH DIABETES THROUGH INTEGRATED APPROACHES.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
11   39 22 A BRIEF BUT COMPREHENSIVE LIFESTYLE EDUCATION PROGRAM BASED ON YOGA REDUCES RISK FACTORS FOR CARDIOVASCULAR DISEASE AND DIABETES MELLITUS. OBJECTIVES: THE OBJECTIVE OF THE STUDY WAS TO STUDY THE SHORT-TERM IMPACT OF A BRIEF LIFESTYLE INTERVENTION BASED ON YOGA ON SOME OF THE BIOCHEMICAL INDICATORS OF RISK FOR CARDIOVASCULAR DISEASE AND DIABETES MELLITUS. DESIGN: THE VARIABLES OF INTEREST WERE MEASURED AT THE BEGINNING (DAY 1) AND END (DAY 10) OF THE INTERVENTION USING A PRE-POST DESIGN. SETTING: THE STUDY IS THE RESULT OF OPERATIONAL RESEARCH CARRIED OUT IN OUR INTEGRAL HEALTH CLINIC (IHC). THE IHC IS AN OUTPATIENT FACILITY WHICH CONDUCTS 8-DAY LIFESTYLE MODIFICATION PROGRAMS BASED ON YOGA FOR PREVENTION AND MANAGEMENT OF CHRONIC DISEASE. A NEW COURSE BEGINS EVERY ALTERNATE WEEK OF THE YEAR. SUBJECTS: THE STUDY IS BASED ON DATA COLLECTED ON 98 SUBJECTS (67 MALE, 31 FEMALE), AGES 20-74 YEARS, WHO ATTENDED ONE OF OUR PROGRAMS. THE SUBJECTS WERE A HETEROGENEOUS GROUP OF PATIENTS WITH HYPERTENSION, CORONARY ARTERY DISEASE, DIABETES MELLITUS, AND A VARIETY OF OTHER ILLNESSES. INTERVENTION: THE INTERVENTION CONSISTED OF ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), RELAXATION TECHNIQUES, GROUP SUPPORT, INDIVIDUALIZED ADVICE, LECTURES AND FILMS ON THE PHILOSOPHY OF YOGA AND THE PLACE OF YOGA IN DAILY LIFE, MEDITATION, STRESS MANAGEMENT, NUTRITION, AND KNOWLEDGE ABOUT THE ILLNESS. OUTCOME MEASURES: THE OUTCOME MEASURES WERE FASTING PLASMA GLUCOSE AND SERUM LIPOPROTEIN PROFILE. THESE VARIABLES WERE DETERMINED IN FASTING BLOOD SAMPLES, TAKEN ON THE FIRST AND LAST DAY OF THE COURSE. RESULTS: FASTING PLASMA GLUCOSE, SERUM TOTAL CHOLESTEROL, LOW-DENSITY LIPOPROTEIN (LDL) CHOLESTEROL, VERY- LDL CHOLESTEROL, THE RATIO OF TOTAL CHOLESTEROL TO HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL, AND TOTAL TRIGLYCERIDES WERE SIGNIFICANTLY LOWER, AND HDL CHOLESTEROL SIGNIFICANTLY HIGHER, ON THE LAST DAY OF THE COURSE COMPARED TO THE FIRST DAY OF THE COURSE. THE CHANGES WERE MORE MARKED IN SUBJECTS WITH HYPERGLYCEMIA OR HYPERCHOLESTEROLEMIA. CONCLUSIONS: THE OBSERVATIONS SUGGEST THAT A SHORT LIFESTYLE MODIFICATION AND STRESS MANAGEMENT EDUCATION PROGRAM LEADS TO FAVORABLE METABOLIC EFFECTS WITHIN A PERIOD OF 9 DAYS.	2005	
                                                                                                                                                                                                                                                                            
12 1453 18 INFLUENCE OF PRANAYAMAS AND YOGA-ASANAS ON SERUM INSULIN, BLOOD GLUCOSE AND LIPID PROFILE IN TYPE 2 DIABETES. A DISTINGUISHABLE FEATURE OF TYPE 2 DIABETES BESIDES HYPERGLYCEMIA AND DERANGED LIPID PROFILE IS AN IMPAIRED INSULIN SECRETION, PERIPHERAL INSULIN RESISTANCE AND OBESITY WHICH HAS BECOME A MAJOR HEALTH CONCERN WORLDWIDE. INDIA WITH AN ESTIMATED 31MILLION DIABETICS IN 2000 AND 79MLLIONS BY THE YR 2030 HAS THE HIGHEST NUMBER OF TYPE 2 DIABETICS IN THE WORLD. IN THIS STUDY, WE AIMED TO SEE IF YOGA-ASANAS AND PRANAYAMAS HAVE ANY INFLUENCE IN MODIFYING CERTAIN BIOCHEMICAL PARAMETERS. SIXTY PATIENTS OF UNCOMPLICATED TYPE 2 DIABETES (AGE 35-60 YRS OF 1-10 YRS DURATION) WERE DIVIDED INTO TWO GROUPS: GROUP 1 (N=30): PERFORMED YOGA ALONG WITH THE CONVENTIONAL HYPOGLYCEMIC MEDICINES AND GROUP 2 (N=30): PATIENTS WHO ONLY RECEIVED CONVENTIONAL MEDICINES. DURATION OF THE STUDY WAS 45 DAYS. BASAL RECORDINGS OF BLOOD GLUCOSE (FASTING AND POST-PRANDIAL), LIPID PROFILE AND SERUM INSULIN WERE TAKEN AT THE TIME OF RECRUITMENT AND THE SECOND READING AFTER FORTY FIVE DAYS. RESULTS SHOWED A SIGNIFICANT IMPROVEMENT IN ALL THE BIOCHEMICAL PARAMETERS IN GROUP 1 WHILE GROUP 2 SHOWED SIGNIFICANT IMPROVEMENT IN ONLY FEW PARAMETERS, THUS SUGGESTING A BENEFICIAL EFFECT OF YOGA REGIMEN ON THESE PARAMETERS IN DIABETIC PATIENTS.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
13 1476 15 INTEGRATED YOGA AND NATUROPATHY MODULE IN MANAGEMENT OF METABOLIC SYNDROME: A CASE REPORT. A 50-YEAR-OLD MALE PARTICIPANT WITH SEDENTARY LIFESTYLE, DIAGNOSED WITH METABOLIC SYNDROME (METS) [OBESITY, TYPE-2 DIABETES MELLITUS, HYPERTENSION] AND HYPOTHYROIDISM SINCE 2013, WAS ADMINISTERED INTEGRATED YOGA AND NATUROPATHY (IYN) FOR 6 WEEKS AS A TAILOR MADE INDIVIDUALIZED PROTOCOL AT THE RESIDENTIAL INTEGRATIVE MEDICAL FACILITY IN BANGALORE BETWEEN OCTOBER AND NOVEMBER 2015. THE RESULTS SHOWED REDUCTION IN WEIGHT (97.9 KG TO 74.6 KG), BODY MASS INDEX (BMI) (35.1 KG/M(2) TO 27.86 KG/M(2)), TOTAL CHOLESTEROL (192 MG% TO 145 MG%), TRIGLYCERIDES (153 MG% TO 90 MG%), LOW DENSITY LIPOPROTEIN (LDL) (124 MG% TO 81 MG%), HIGH DENSITY LIPOPROTEIN (HDL) (40 MG% TO 46 MG%), FASTING BLOOD GLUCOSE (110 MG/DL TO 75 MG/DL), POSTPRANDIAL GLUCOSE (267 MG/DL TO 100 MG/DL), GLYCATED HEMOGLOBIN (HBA1C) (7.8%-7.1%), THYROID STIMULATING HORMONE (TSH) (6.90 MUIU/ML TO 3.052 MUIU/ML). FOLLOWING THE INTERVENTION, THE ANTI-HYPERTENSIVE, ORAL HYPOGLYCEMIC, THYROID RAISING AND ANALGESIC MEDICINES WERE NOT REQUIRED TO BE CONTINUED. HIS KNEE PAIN MINIMIZED ON DISCHARGE AS OBSERVED ON A VISUAL ANALOG SCALE. HE HAD AN IMPROVED FEELING OF WELLNESS AND OVERALL FUNCTIONAL HEALTH. ALL HIS PARAMETERS WERE WITHIN NORMAL RANGE AT THE 12-WEEKS FOLLOW-UP, AS HE HAD INCORPORATED THE LIFESTYLE PROGRAM INTO HIS DAILY ROUTINE. THIS CASE REPORT SUGGESTS THAT LIFESTYLE CHANGE BY INTEGRATION OF SPECIFIC NON-DRUG YOGA AND NATUROPATHIC INTERVENTION IS USEFUL IN THE MANAGEMENT OF METS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
14 1305 28 HATHA YOGA PRACTICES: ENERGY EXPENDITURE, RESPIRATORY CHANGES AND INTENSITY OF EXERCISE. THE AIM OF THIS STUDY WAS TO CRITICALLY OBSERVE THE ENERGY EXPENDITURE, EXERCISE INTENSITY AND RESPIRATORY CHANGES DURING A FULL YOGA PRACTICE SESSION. OXYGEN CONSUMPTION ([FORMULA: SEE TEXT]), CARBON DIOXIDE OUTPUT ([FORMULA: SEE TEXT]), PULMONARY VENTILATION ([FORMULA: SEE TEXT]E), RESPIRATORY RATE (FR) AND TIDAL VOLUME (VT), WERE MEASURED IN 16 PHYSICAL POSTURE (ASANAS), FIVE YOGA BREATHING MANEUVERS (BM) AND TWO TYPES OF MEDITATION. TWENTY MALE (AGE 27.3 +/- 3.5 YEARS, HEIGHT 166.6 +/- 5.4 CM AND BODY WEIGHT 58.8 +/- 9.6 KG) YOGA INSTRUCTORS WERE STUDIED. THEIR MAXIMAL OXYGEN CONSUMPTION ([FORMULA: SEE TEXT]) WAS RECORDED. THE EXERCISE INTENSITY IN ASANAS WAS EXPRESSED IN PERCENTAGE [FORMULA: SEE TEXT] . IN ASANAS, EXERCISE INTENSITY VARIED FROM 9.9 TO 26.5% OF [FORMULA: SEE TEXT] . HIGHEST ENERGY COST WAS 3.02 KCAL MIN(-1). IN BM HIGHEST [FORMULA: SEE TEXT]E WAS 53.7 +/- 15.5 L MIN(-1). VT WAS 0.97 +/- 0.59, 1.41 +/- 1.27 AND 1.28 +/- L/BREATH WITH CORRESPONDING FR OF 14.0 +/- 5.3, 10.0 +/- 6.35, 10.0 +/- 5.8 BREATHS/MIN. AVERAGE ENERGY EXPENDITURE IN ASANAS, BM AND MEDITATION WERE 2.29, 1.91 AND 1.37 KCAL MIN(-1), RESPECTIVELY. METABOLIC RATE WAS GENERALLY IN THE RANGE OF 1-2 METABOLIC EQUIVALENTS (MET) EXCEPT IN THREE ASANAS WHERE IT WAS >2 MET. [FORMULA: SEE TEXT] WAS 0.27 +/- 0.05 AND 0.24 +/- 0.04 L MIN(-1) IN MEDITATION AND SHAVASANA, RESPECTIVELY. ALTHOUGH YOGIC PRACTICES ARE LOW INTENSITY EXERCISES WITHIN LACTATE THRESHOLD, PHYSICAL PERFORMANCE IMPROVEMENT IS POSSIBLE OWING TO BOTH BETTER ECONOMY OF BREATHING BY BM AND ALSO BY IMPROVEMENT IN CARDIOVASCULAR RESERVE. OTHER FACTORS SUCH AS PSYCHO-PHYSIOLOGICAL AND BETTER RELAXATION MAY CONTRIBUTE TO IT.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
15  751 19 EFFECT OF SHORT TERM YOGA PRACTICE ON VENTILATORY FUNCTION TESTS. TWENTYFIVE NORMAL MALE VOLUNTEERS UNDERGOING A TEN WEEKS COURSE IN THE PRACTICE OF YOGA HAVE BEEN STUDIED BY SOME PARAMETERS OF VENTILATORY FUNCTIONS TESTS. THE OBSERVATIONS RECORDED AT THE END OF TEN WEEKS OF THE COURSE HAVE SHOWN IMPROVED VENTILATORY FUNCTIONS IN THE FORM OF LOWERED RESPIRATORY RATE, INCREASED FORCED VITAL CAPACITY, FEV1, MAXIMUM BREATHING CAPACITY AND BREATH HOLDING TIME, WHILE TIDAL VOLUME AND %FEV1, DID NOT REVEAL ANY SIGNIFICANT CHANGE. THUS, A COMBINED PRACTICE OF YOGA SEEMS TO BE BENEFICIAL ON RESPIRATORY EFFICIENCY.	1988	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
16  438 25 CARDIOVASCULAR AND RESPIRATORY EFFECT OF YOGIC SLOW BREATHING IN THE YOGA BEGINNER: WHAT IS THE BEST APPROACH? SLOW BREATHING INCREASES CARDIAC-VAGAL BAROREFLEX SENSITIVITY (BRS), IMPROVES OXYGEN SATURATION, LOWERS BLOOD PRESSURE, AND REDUCES ANXIETY. WITHIN THE YOGA TRADITION SLOW BREATHING IS OFTEN PAIRED WITH A CONTRACTION OF THE GLOTTIS MUSCLES. THIS RESISTANCE BREATH "UJJAYI" IS PERFORMED AT VARIOUS RATES AND RATIOS OF INSPIRATION/EXPIRATION. TO TEST WHETHER UJJAYI HAD ADDITIONAL POSITIVE EFFECTS TO SLOW BREATHING, WE COMPARED BRS AND VENTILATORY CONTROL UNDER DIFFERENT BREATHING PATTERNS (EQUAL/UNEQUAL INSPIRATION/EXPIRATION AT 6 BREATH/MIN, WITH/WITHOUT UJJAYI), IN 17 YOGA-NAIVE YOUNG HEALTHY PARTICIPANTS. BRS INCREASED WITH SLOW BREATHING TECHNIQUES WITH OR WITHOUT EXPIRATORY UJJAYI (P < 0.05 OR HIGHER) EXCEPT WITH INSPIRATORY + EXPIRATORY UJJAYI. THE MAXIMAL INCREASE IN BRS AND DECREASE IN BLOOD PRESSURE WERE FOUND IN SLOW BREATHING WITH EQUAL INSPIRATION AND EXPIRATION. THIS CORRESPONDED WITH A SIGNIFICANT IMPROVEMENT IN OXYGEN SATURATION WITHOUT INCREASE IN HEART RATE AND VENTILATION. UJJAYI SHOWED SIMILAR INCREASE IN OXYGEN SATURATION BUT SLIGHTLY LESSER IMPROVEMENT IN BAROREFLEX SENSITIVITY WITH NO CHANGE IN BLOOD PRESSURE. THE SLOW BREATHING WITH EQUAL INSPIRATION AND EXPIRATION SEEMS THE BEST TECHNIQUE FOR IMPROVING BAROREFLEX SENSITIVITY IN YOGA-NAIVE SUBJECTS. THE EFFECTS OF UJJAYI SEEMS DEPENDENT ON INCREASED INTRATHORACIC PRESSURE THAT REQUIRES GREATER EFFORT THAN NORMAL SLOW BREATHING.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
17 1508 12 IS MAN ABLE TO BREATHE ONCE A MINUTE FOR AN HOUR?: THE EFFECT OF YOGA RESPIRATION ON BLOOD GASES. THE VENTILATORY RESPONSE TO HYPERCAPNIA AND ARTERIAL BLOOD GASES DURING UJJAI RESPIRATION OF ONCE PER MINUTE FOR AN HOUR WERE DETERMINED IN A PROFESSIONAL HATHA YOGI. THE RESULTS SUGGEST THAT LOWER CHEMOSENSITIVITY TO HYPERCAPNIA IN YOGA PRACTITIONERS MAY BE DUE TO AN ADAPTATION TO LOW ARTERIAL PH AND HIGH PACO2 FOR LONG PERIODS.	2002	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
18  867 25 EFFECT OF YOGA REGIMEN ON LUNG FUNCTIONS INCLUDING DIFFUSION CAPACITY IN CORONARY ARTERY DISEASE PATIENTS: A RANDOMIZED CONTROLLED STUDY. BACKGROUND: LUNG FUNCTIONS ARE FOUND TO BE IMPAIRED IN CORONARY ARTERY DISEASE (CAD), CONGESTIVE HEART FAILURE, LEFT VENTRICULAR DYSFUNCTION, AND AFTER CARDIAC SURGERY. DIFFUSION CAPACITY PROGRESSIVELY WORSENS AS THE SEVERITY OF CAD INCREASES DUE TO REDUCTION IN LUNG TISSUE PARTICIPATING IN GAS EXCHANGE. AIMS AND OBJECTIVES: PRANAYAMA BREATHING EXERCISES AND YOGIC POSTURES MAY PLAY AN IMPRESSIVE ROLE IN IMPROVING CARDIO-RESPIRATORY EFFICIENCY AND FACILITATING GAS DIFFUSION AT THE ALVEOLO-CAPILLARY MEMBRANE. THIS STUDY WAS DONE TO SEE THE EFFECT OF YOGA REGIMEN ON LUNG FUNCTIONS PARTICULARLY DIFFUSION CAPACITY IN CAD PATIENTS. MATERIALS AND METHODS: A TOTAL OF 80 STABLE CAD PATIENTS BELOW 65 YEARS OF AGE OF BOTH SEXES WERE SELECTED AND RANDOMIZED INTO TWO GROUPS OF 40 EACH. GROUP I CAD PATIENTS WERE GIVEN YOGA REGIMEN FOR 3 MONTHS WHICH CONSISTED OF YOGIC POSTURES, PRANAYAMA BREATHING EXERCISES, DIETARY MODIFICATION, AND HOLISTIC TEACHING ALONG WITH THEIR CONVENTIONAL MEDICINE WHILE GROUP II CAD PATIENTS WERE PUT ONLY ON CONVENTIONAL MEDICINE. LUNG FUNCTIONS INCLUDING DIFFUSION CAPACITY WERE RECORDED THRICE IN BOTH THE GROUPS: 0 DAY AS BASELINE, 22(ND) DAY AND ON 90(TH) DAY BY USING COMPUTERIZED MS MEDISOFT CARDIO-RESPIRATORY INSTRUMENT, HYP'AIR COMPACT MODEL OF CARDIO-RESPIRATORY TESTING MACHINE WAS MANUFACTURED BY P K MORGAN, INDIA. THE RECORDED PARAMETERS WERE STATISTICALLY ANALYZED BY REPEATED MEASURES ANOVA FOLLOWED BY TUKEY'S TEST IN BOTH THE GROUPS. CARDIOVASCULAR PARAMETERS WERE ALSO COMPARED BEFORE AND AFTER INTERVENTION IN BOTH THE GROUPS. RESULTS: STATISTICALLY SIGNIFICANT IMPROVEMENTS WERE SEEN IN SLOW VITAL CAPACITY, FORCED VITAL CAPACITY, PEAK EXPIRATORY FLOW RATE, MAXIMUM VOLUNTARY VENTILATION, AND DIFFUSION FACTOR/ TRANSFER FACTOR OF LUNG FOR CARBON MONOXIDE AFTER 3 MONTHS OF YOGA REGIMEN IN GROUP I. FORCED EXPIRATORY VOLUME IN 1(ST) SEC (FEV1), AND FEV1 % ALSO SHOWED A TREND TOWARD IMPROVEMENT ALTHOUGH NOT STATISTICALLY SIGNIFICANT. HR, SBP AND DBP ALSO SHOWED SIGNIFICANT IMPROVEMENT IN GROUP-I PATIENTS WHO FOLLOWED YOGA REGIMEN. CONCLUSIONS: YOGA REGIMEN WAS FOUND TO IMPROVE LUNG FUNCTIONS AND DIFFUSION CAPACITY IN CAD PATIENTS BESIDES IMPROVING CARDIOVASCULAR FUNCTIONS. THUS, IT CAN BE USED AS A COMPLIMENTARY OR ADJUNCT THERAPY ALONG WITH THE CONVENTIONAL MEDICINE FOR THEIR TREATMENT AND REHABILITATION.	2015	

19 1904 25 RETARDATION OF CORONARY ATHEROSCLEROSIS WITH YOGA LIFESTYLE INTERVENTION. BACKGROUND: YOGA HAS POTENTIAL FOR BENEFIT FOR PATIENTS WITH CORONARY ARTERY DISEASE THOUGH OBJECTIVE, ANGIOGRAPHIC STUDIES ARE LACKING. MATERIAL AND METHODS: WE EVALUATED POSSIBLE ROLE OF LIFESTYLE MODIFICATION INCORPORATING YOGA, ON RETARDATION OF CORONARY ATHEROSCLEROTIC DISEASE. IN THIS PROSPECTIVE, RANDOMIZED, CONTROLLED TRIAL, 42 MEN WITH ANGIOGRAPHICALLY PROVEN CORONARY ARTERY DISEASE (CAD) WERE RANDOMIZED TO CONTROL (N = 21) AND YOGA INTERVENTION GROUP (N = 21) AND WERE FOLLOWED FOR ONE YEAR. THE ACTIVE GROUP WAS TREATED WITH A USER-FRIENDLY PROGRAM CONSISTING OF YOGA, CONTROL OF RISK FACTORS, DIET CONTROL AND MODERATE AEROBIC EXERCISE. THE CONTROL GROUP WAS MANAGED BY CONVENTIONAL METHODS I.E. RISK FACTOR CONTROL AND AMERICAN HEART ASSOCIATION STEP I DIET. RESULTS: AT ONE YEAR, THE YOGA GROUPS SHOWED SIGNIFICANT REDUCTION IN NUMBER OF ANGINAL EPISODES PER WEEK, IMPROVED EXERCISE CAPACITY AND DECREASE IN BODY WEIGHT. SERUM TOTAL CHOLESTEROL, LDL CHOLESTEROL AND TRIGLYCERIDE LEVELS ALSO SHOWED GREATER REDUCTIONS AS COMPARED WITH CONTROL GROUP. REVASCULARISATION PROCEDURES (CORONARY ANGIOPLASTY OR BYPASS SURGERY) WERE LESS FREQUENTLY REQUIRED IN THE YOGA GROUP (ONE VERSUS EIGHT PATIENTS; RELATIVE RISK = 5.45; P = 0.01). CORONARY ANGIOGRAPHY REPEATED AT ONE YEAR SHOWED THAT SIGNIFICANTLY MORE LESIONS REGRESSED (20% VERSUS 2%) AND LESS LESIONS PROGRESSED (5% VERSUS 37%) IN THE YOGA GROUP (CHI-SQUARE = 24.9; P < 0.0001). THE COMPLIANCE TO THE TOTAL PROGRAM WAS EXCELLENT AND NO SIDE EFFECTS WERE OBSERVED. CONCLUSION: YOGA LIFESTYLE INTERVENTION RETARDS PROGRESSION AND INCREASES REGRESSION OF CORONARY ATHEROSCLEROSIS IN PATIENTS WITH SEVERE CORONARY ARTERY DISEASE. IT ALSO IMPROVES SYMPTOMATIC STATUS, FUNCTIONAL CLASS AND RISK FACTOR PROFILE.	2000	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
20 1376 19 IMPACT OF HATHA YOGA ON THE AIRWAY RESISTANCES IN HEALTHY INDIVIDUALS AND ALLERGIC RHINITIS PATIENTS. THERE HAVE BEEN LIMITED STUDIES ON HATHA YOGA TRAINING AS A COMPLEMENTARY THERAPY TO MANAGE THE SYMPTOMS OF ALLERGIC RHINITIS. THE MAIN AIM OF THE STUDY WAS TO CHECK THE IMPACT OF HATHA YOGASANAS ON THE AIRWAY RESISTANCES IN HEALTHY VOLUNTEERS, A BASELINE DATA CAN BE ESTABLISHED AND ALSO TO STUDY THE IMPACT OF HATHA YOGASANAS ON THE AIRWAY RESISTANCES IN ALLERGIC RHINITIS PATIENTS IN BANGALORE, INDIA. THIS IS A PROSPECTIVE CASE SERIES OF 51 HEALTHY VOLUNTEERS (18 MALES AND 33 FEMALES) GROUP 1 AND 51 ALLERGIC RHINITIS PATIENTS (18 MALES AND 33 FEMALES) GROUP 2. THE OBJECTIVE ANALYSIS OF THE UPPER AIRWAY RESISTANCE WAS MEASURED USING A RHINOMANOMETER AND THE LOWER AIRWAY RESISTANCE WAS MEASURED USING A SPIROMETER. THEN THE SUBJECTS PRACTICED SPECIFIC HATHA YOGASANAS FOR THREE MONTHS. THEN THE AIRWAY RESISTANCE TESTS WERE AGAIN DONE AT 3 MONTHS INTERVAL. THE SUBJECTIVE ANALYSIS WAS DONE PRE YOGA AND POST YOGA USING THE SHORT FORM-12 (SF-12) AND SINO NASAL OUTCOME TEST (SNOT) QUESTIONNAIRES TO ASSESS THE QUALITY OF LIFE. THE DATA WAS ANALYZED BY DOING A PAIRED (2-TAILED) T TEST, USING SPSS (SOFTWARE PACKAGE FOR SOCIAL SCIENCES) VERSION 16. TOTAL NASAL AIRWAY RESISTANCE PRE YOGA AND POST YOGA IN 51 HEALTHY VOLUNTEERS HAD SIGNIFICANTLY REDUCED AT 150 PA AND THE FORCED VITAL CAPACITY(FVC) PRE YOGA AND POST YOGA HAD SIGNIFICANTLY INCREASED,FORCED EXPIRATORY VOLUME (FEV1) & % RESIDUAL STANDARD DEVIATION (%RSD) HAD INCREASED BUT NOT SIGNIFICANT. THE PHYSICAL COMPONENT SCORE (PCS) AND MENTAL COMPONENT SCORE (MCS) OF THE SF-12 HEALTH SURVEY QUESTIONNAIRE HAD SIGNIFICANTLY IMPROVED WITH AND THE SNOT QUESTIONNAIRE SCORE HAD SIGNIFICANTLY REDUCED. THE TOTAL NASAL AIRWAY RESISTANCE IN 51 ALLERGIC RHINITIS HAD SIGNIFICANTLY REDUCED AT 150 PA AND THE FVC PRE YOGA AND POST YOGA SHOWED INCREASE BUT CHANGE WAS NOT SIGNIFICANT, FEV1 PRE YOGA AND POST YOGA HAD SIGNIFICANTLY INCREASED, %RSD PRE YOGA AND POST YOGA HAD SIGNIFICANTLY INCREASED. THE PCS AND MCS OF THE SF-12 HEALTH SURVEY QUESTIONNAIRE HAD SIGNIFICANTLY INCREASED AND THE SNOT QUESTIONNAIRE SCORE HAD SIGNIFICANTLY DECREASED. THE SCIENTIFIC DOCUMENTATION OF THE IMPACT OF HATHA YOGA ON THE AIRWAY RESISTANCES CAN BE AN EYE OPENER IN THE MANAGEMENT OF SEVERAL OTHER DISEASES OF THE AIRWAYS.	2019