1 1524 138 ISOMETRIC YOGA-LIKE MANEUVERS IMPROVE ADOLESCENT IDIOPATHIC SCOLIOSIS-A NONRANDOMIZED CONTROL TRIAL. OBJECTIVE: ASSESS THERAPEUTIC VALUE OF SPECIFIC YOGA POSES FOR THORACIC AND LUMBAR ADOLESCENT IDIOPATHIC SCOLIOSIS (AIS) TAUGHT IN OFFICE OR INTERNET. STUDY DESIGN: NONRANDOMIZED CONTROL TRIAL: FIFTY-SIX ADOLESCENTS (MEAN AGE 14.0 YEARS; MEAN RISSER 3.0) WERE RECRUITED FROM OUR CLINIC; 41 DID THE SIDE-PLANK, THE HALF-MOON AND ELEVATED SIDE PLANK POSES AS APPROPRIATE (TREATMENT GROUP) AND 15 DID NOT (CONTROLS). THIRTY CURVES WERE TREATED IN OFFICE, 30 VIA INTERNET. CURVE CHANGE WAS EVALUATED BY BLINDED SERIAL COBB ANGLES, AND ANALYZED USING MANN-WHITNEY U, PAIRED T-TESTS AND CHI(2). RESULTS: MEAN LUMBAR AND THORACOLUMBAR COBB ANGLE CHANGE WAS -9.2 (95% CI = -11.8, -6.6) IN THE TREATMENT GROUP AND 5.4 (95% CI = 1.7, 9.0) IN CONTROLS. BOTH TREATMENT GROUP IMPROVEMENT AND DETERIORATION IN CONTROLS WERE SIGNIFICANT (TREATMENT GROUP: PAIRED T-TEST T = -7.1, DF = 40, P = .000; CONTROLS: T = 3.2, DF = 12, P = .008). MEAN THORACIC COBB ANGLE CHANGE WAS -7.1 (95% CI = -13.1, -1.2) IN THE TREATMENT GROUP AND 9.3 (95% CI = 4.5, 14.6) IN CONTROLS. BOTH CHANGES WERE SIGNIFICANT (PAIRED T-TEST T = -3.3, DF = 21, P = .022 FOR TREATMENT GROUP; T = 4.5, DF = 5, P = .006 FOR CONTROLS). NINE INTERNET PATIENTS WERE NON-COMPLIANT VS. 6 OFFICE PATIENTS. OFFICE PATIENTS IMPROVED 1.6 DEGREES/MONTH OR 5.5%/MONTH; INTERNET PATIENTS IMPROVED .72 DEGREES/MONTH OR 3.3%/MONTH. CONCLUSION: THESE YOGA POSES SHOW PROMISE FOR REVERSING ADOLESCENT IDIOPATHIC SCOLIOSIS. TELEMEDICINE HAD GREATER NON-COMPLIANCE AND LOWER EFFICACY BUT STILL PRODUCED PATIENT IMPROVEMENT.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
2 1089  13 EFFECTS OF YOGA ON THE AUTONOMIC NERVOUS SYSTEM, GAMMA-AMINOBUTYRIC-ACID, AND ALLOSTASIS IN EPILEPSY, DEPRESSION, AND POST-TRAUMATIC STRESS DISORDER. A THEORY IS PROPOSED TO EXPLAIN THE BENEFITS OF YOGA PRACTICES IN DIVERSE, FREQUENTLY COMORBID MEDICAL CONDITIONS BASED ON THE CONCEPT THAT YOGA PRACTICES REDUCE ALLOSTATIC LOAD IN STRESS RESPONSE SYSTEMS SUCH THAT OPTIMAL HOMEOSTASIS IS RESTORED. IT IS HYPOTHESIZED THAT STRESS INDUCES (1) IMBALANCE OF THE AUTONOMIC NERVOUS SYSTEM (ANS) WITH DECREASED PARASYMPATHETIC NERVOUS SYSTEM (PNS) AND INCREASED SYMPATHETIC NERVOUS SYSTEM (SNS) ACTIVITY, (2) UNDERACTIVITY OF THE GAMMA AMINO-BUTYRIC ACID (GABA) SYSTEM, THE PRIMARY INHIBITORY NEUROTRANSMITTER SYSTEM, AND (3) INCREASED ALLOSTATIC LOAD. IT IS FURTHER HYPOTHESIZED THAT YOGA-BASED PRACTICES (4) CORRECT UNDERACTIVITY OF THE PNS AND GABA SYSTEMS IN PART THROUGH STIMULATION OF THE VAGUS NERVES, THE MAIN PERIPHERAL PATHWAY OF THE PNS, AND (5) REDUCE ALLOSTATIC LOAD. DEPRESSION, EPILEPSY, POST TRAUMATIC STRESS DISORDER (PTSD), AND CHRONIC PAIN EXEMPLIFY MEDICAL CONDITIONS THAT ARE EXACERBATED BY STRESS, HAVE LOW HEART RATE VARIABILITY (HRV) AND LOW GABAERGIC ACTIVITY, RESPOND TO PHARMACOLOGIC AGENTS THAT INCREASE ACTIVITY OF THE GABA SYSTEM, AND SHOW SYMPTOM IMPROVEMENT IN RESPONSE TO YOGA-BASED INTERVENTIONS. THE OBSERVATION THAT TREATMENT RESISTANT CASES OF EPILEPSY AND DEPRESSION RESPOND TO VAGAL NERVE STIMULATION CORROBORATES THE NEED TO CORRECT PNS UNDERACTIVITY AS PART OF A SUCCESSFUL TREATMENT PLAN IN SOME CASES. ACCORDING TO THE PROPOSED THEORY, THE DECREASED PNS AND GABAERGIC ACTIVITY THAT UNDERLIES STRESS-RELATED DISORDERS CAN BE CORRECTED BY YOGA PRACTICES RESULTING IN AMELIORATION OF DISEASE SYMPTOMS. THIS HAS FAR-REACHING IMPLICATIONS FOR THE INTEGRATION OF YOGA-BASED PRACTICES IN THE TREATMENT OF A BROAD ARRAY OF DISORDERS EXACERBATED BY STRESS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                             
3 1405  28 IMPACT OF YOGA ON FUNCTIONAL OUTCOMES IN BREAST CANCER SURVIVORS WITH AROMATASE INHIBITOR-ASSOCIATED ARTHRALGIAS. ARTHRALGIA AFFECTS POSTMENOPAUSAL BREAST CANCER SURVIVORS (BCSS) RECEIVING AROMATASE INHIBITORS (AIS). THIS STUDY AIMS TO ESTABLISH THE FEASIBILITY OF STUDYING THE IMPACT OF YOGA ON OBJECTIVE FUNCTIONAL OUTCOMES, PAIN, AND HEALTH-RELATED QUALITY OF LIFE (HR-QOL) FOR AI-ASSOCIATED ARTHRALGIA (AIAA). POSTMENOPAUSAL WOMEN WITH STAGE I TO III BREAST CANCER WHO REPORTED AIAA WERE ENROLLED IN A SINGLE-ARM PILOT TRIAL. A YOGA PROGRAM WAS PROVIDED TWICE A WEEK FOR 8 WEEKS. THE FUNCTIONAL REACH (FR) AND SIT AND REACH (SR) WERE EVALUATED AS PRIMARY OUTCOMES. PAIN, AS MEASURED BY THE BRIEF PAIN INVENTORY (BPI), SELF-REPORTED PATIENT SPECIFIC FUNCTIONAL SCALE (PSFS), AND FUNCTIONAL ASSESSMENT OF CANCER THERAPY-BREAST (FACT-B) WERE SECONDARY OUTCOMES. PAIRED T TESTS WERE USED FOR ANALYSIS, AND 90% PROVIDED DATA FOR ASSESSMENT AT THE END OF THE INTERVENTION. PARTICIPANTS EXPERIENCED SIGNIFICANT IMPROVEMENT IN BALANCE, AS MEASURED BY FR, AND FLEXIBILITY, AS MEASURED BY SR. THE PSFS IMPROVED FROM 4.55 TO 7.21, AND HR-QOL MEASURED BY FACT-B ALSO IMPROVED; BOTH P < .05. THE SCORE FOR THE PAIN SEVERITY SUBSCALE OF THE BPI REDUCED. NO ADVERSE EVENTS NOR DEVELOPMENT OR WORSENING OF LYMPHEDEMA WAS OBSERVED. IN ALL, 80% OF PARTICIPANTS ADHERED TO THE HOME PROGRAM. PRELIMINARY DATA SUGGEST THAT YOGA MAY REDUCE PAIN AND IMPROVE BALANCE AND FLEXIBILITY IN BCSS WITH AIAA. A RANDOMIZED CONTROLLED TRIAL IS NEEDED TO ESTABLISH THE DEFINITIVE EFFICACY OF YOGA FOR OBJECTIVE FUNCTIONAL IMPROVEMENT IN BCSS RELATED TO AIAA.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
4 2727  28 YOGA NIDRA RELAXATION INCREASES HEART RATE VARIABILITY AND IS UNAFFECTED BY A PRIOR BOUT OF HATHA YOGA. OBJECTIVE: THE MEASUREMENT OF HEART RATE VARIABILITY (HRV) IS OFTEN APPLIED AS AN INDEX OF AUTONOMIC NERVOUS SYSTEM (ANS) BALANCE AND, THEREFORE, MYOCARDIAL STABILITY. PREVIOUS STUDIES HAVE SUGGESTED THAT RELAXATION OR MIND-BODY EXERCISE CAN INFLUENCE ANS BALANCE POSITIVELY AS MEASURED BY HRV BUT MAY ACT VIA DIFFERENT MECHANISMS. NO STUDIES, TO THE AUTHORS' KNOWLEDGE, HAVE EXAMINED THE ACUTE RESPONSE IN HRV TO INTERVENTIONS COMBINING RELAXATION AND MIND-BODY EXERCISE. THE OBJECTIVE OF THIS STUDY WAS TO COMPARE THE ACUTE HRV RESPONSES TO YOGA NIDRA RELAXATION ALONE VERSUS YOGA NIDRA RELAXATION PRECEDED BY HATHA YOGA. DESIGN: THIS WAS A RANDOMIZED COUNTER-BALANCED TRIAL. SETTING: THE TRIAL WAS CONDUCTED IN A UNIVERSITY EXERCISE PHYSIOLOGY LABORATORY. SUBJECTS: SUBJECTS INCLUDED 20 WOMEN AND MEN (29.15+/-6.98 YEARS OF AGE, WITH A RANGE OF 18-47 YEARS). INTERVENTIONS: PARTICIPANTS COMPLETED A YOGA PLUS RELAXATION (YR) SESSION AND A RELAXATION ONLY (R) SESSION. RESULTS: THE YR CONDITION PRODUCED SIGNIFICANT CHANGES FROM BASELINE IN HEART RATE (HR; BEATS PER MINUTE [BPM], P<0.001) AND INDICES OF HRV: R-R (MS, P<0.001), PNN50 (%, P=0.009), LOW FREQUENCY (LF; %, P=0.008) AND HIGH FREQUENCY (HF; %, P=0.035). THE R CONDITION PRODUCED SIGNIFICANT CHANGES FROM BASELINE IN HEART RATE (BPM, P<0.001) AS WELL AS INDICES OF HRV: R-R (MS, P<0.001), HF (MS(2), P=0.004), LF (%, P=0.005), HF (%, P=0.008) AND LF:HF RATIO (%, P=0.008). THERE WERE NO SIGNIFICANT DIFFERENCES BETWEEN CONDITIONS AT BASELINE NOR FOR THE CHANGES FROM BASELINE FOR ANY OF THE VARIABLES. CONCLUSIONS: THESE CHANGES DEMONSTRATE A FAVORABLE SHIFT IN AUTONOMIC BALANCE TO THE PARASYMPATHETIC BRANCH OF THE ANS FOR BOTH CONDITIONS, AND THAT YOGA NIDRA RELAXATION PRODUCES FAVORABLE CHANGES IN MEASURES OF HRV WHETHER ALONE OR PRECEDED BY A BOUT OF HATHA YOGA.	2012	
                                                                                                                                                                                                                                                                                                                                                       
5 2826  26 YOGA VERSUS MASSAGE IN THE TREATMENT OF AROMATASE INHIBITOR-ASSOCIATED KNEE JOINT PAIN IN BREAST CANCER SURVIVORS: A RANDOMIZED CONTROLLED TRIAL. AROMATASE INHIBITORS (AIS) ARE STANDARD ADJUVANT THERAPY FOR POSTMENOPAUSAL WOMEN WITH OESTROGEN RECEPTOR-POSITIVE, EARLY-STAGE, AND METASTATIC BREAST CANCER. ALTHOUGH EFFECTIVE, THE RISK OF FALLS DUE TO AI-ASSOCIATED KNEE JOINT PAIN SIGNIFICANTLY INCREASED. THE AIM OF THIS STUDY WAS TO EVALUATE THE THERAPEUTIC EFFECTS OF YOGA AND MASSAGE ON AI-ASSOCIATED KNEE JOINT PAIN. BREAST CANCER SURVIVORS WERE RANDOMLY ASSIGNED TO A 6-WEEK YOGA INTERVENTION-2-WEEK REST-6-WEEK MASSAGE EXPOSURE (YOGA FIRST, N = 30) OR A 6-WEEK MASSAGE INTERVENTION-2-WEEK REST-6-WEEK YOGA EXPOSURE (MASSAGE FIRST, N = 30). EVALUATIONS OF THE TREATMENT EFFICACY WERE MADE AT BASELINE, POST-INTERVENTION, AND POST-EXPOSURE USING THE WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX (WOMAC) SCALE, PLASMA CYTOKINE LEVELS, AND CHANGES IN MERIDIAN ENERGY. THE RESULTS SHOWED THAT YOGA, SUPERIOR TO MASSAGE INTERVENTION, SIGNIFICANTLY REDUCED AI-ASSOCIATED KNEE JOINT PAIN, AS DEMONSTRATED BY THE WOMAC PAIN SCORE. THE YOGA INTERVENTION IMPROVEMENTS WERE ALSO ASSOCIATED WITH CHANGES IN PLASMA CYTOKINE LEVELS AND MERIDIAN ENERGY CHANGES. IN CONCLUSION, THIS STUDY PROVIDES SCIENTIFIC EVIDENCE THAT YOGA WAS MORE EFFECTIVE THAN MASSAGE FOR REDUCING AI-ASSOCIATED KNEE JOINT PAIN. MERIDIAN ENERGY CHANGES MAY PROVIDE ANOTHER SCIENTIFIC, OBJECTIVE, NON-INVASIVE WAY TO MONITOR THE THERAPEUTIC EFFECTS OF YOGA AND INVESTIGATE ANOTHER ALTERNATIVE, COMPLEMENTARY MEDICINE.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
6 1004  19 EFFECTS OF MIND(-)BODY EXERCISES (TAI CHI/YOGA) ON HEART RATE VARIABILITY PARAMETERS AND PERCEIVED STRESS: A SYSTEMATIC REVIEW WITH META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: HEART RATE VARIABILITY (HRV) AS AN ACCURATE, NONINVASIVE MEASURE OF THE AUTONOMOUS NERVOUS SYSTEM (ANS) CAN REFLECT MENTAL HEALTH (E.G., STRESS, DEPRESSION, OR ANXIETY). TAI CHI AND YOGA (TAI CHI/YOGA), AS THE MOST WIDELY PRACTICED MIND(-)BODY EXERCISES, HAVE SHOWN POSITIVE OUTCOMES OF MENTAL HEALTH. TO DATE, NO SYSTEMATIC REVIEW REGARDING THE LONG-LASTING EFFECTS OF TAI CHI/YOGA ON HRV PARAMETERS AND PERCEIVED STRESS HAS BEEN CONDUCTED. OBJECTIVE: TO CRITICALLY EVALUATE THE EXISTING LITERATURE ON THIS TOPIC. METHODS: FIVE ELECTRONIC DATABASES (WEB OF SCIENCE, PUBMED, SCOPUS, SPORTDISCUS AND COCHRANE LIBRARY) WERE SEARCHED FROM THE START OF THE RESEARCH PROJECT TO JULY 2018. STUDY SELECTION, DATA EXTRACTION, AND STUDY QUALITY ASSESSMENT WERE INDEPENDENTLY CARRIED OUT BY TWO REVIEWERS. THE POTENTIALLY IDENTIFIED RANDOMIZED CONTROLLED TRIALS (RCT) REPORTED THE USEFUL QUANTITATIVE DATA THAT WERE INCLUDED ONLY FOR META-ANALYSIS. RESULTS: META-ANALYSIS OF 17 MEDIUM-TO-HIGH QUALITY RCTS SHOWED SIGNIFICANTLY BENEFICIAL EFFECTS ON HRV PARAMETERS (NORMALIZED LOW-FREQUENCY, HEDGE'S G = -0.39, 95% CI -0.39 TO -0.56, P < 0.001, I2 = 11.62%; NORMALIZED HIGH-FREQUENCY, HEDGE'S G = 0.37, 95% CI 0.22 TO -0.52, P < 0.001, I2 = 0%; LOW-FREQUENCY TO HIGH-FREQUENCY RATIO, HEDGE'S G = -0.58, 95% CI -0.81 TO -0.35, P < 0.001, I2 = 53.78%) AND STRESS LEVEL (HEDGE'S G = -0.80, 95% CI -1.17 TO -0.44, P < 0.001, I2 = 68.54%). CONCLUSIONS: STRESS REDUCTION MAY BE ATTRIBUTED TO SYMPATHETIC-VAGAL BALANCE MODULATED BY MIND(-)BODY EXERCISES. TAI CHI/YOGA COULD BE AN ALTERNATIVE METHOD FOR STRESS REDUCTION FOR PEOPLE WHO LIVE UNDER HIGH STRESS OR NEGATIVE EMOTIONS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                            
7  164  30 A RANDOMIZED CONTROL TRIAL OF THE EFFECT OF YOGA ON GUNAS (PERSONALITY) AND SELF ESTEEM IN NORMAL HEALTHY VOLUNTEERS. BACKGROUND/AIMS: TO STUDY THE EFFICACY OF YOGA ON GUNAS (PERSONALITY) AND SELF ESTEEM IN NORMAL ADULTS THROUGH A RANDOMIZED COMPARATIVE STUDY. MATERIALS AND METHODS: OF THE 1228 PERSONS WHO ATTENDED MOTIVATIONAL LECTURES, 226 SUBJECTS AGED 18-71 YEARS, OF BOTH SEXES, WHO SATISFIED THE INCLUSION AND EXCLUSION CRITERIA, AND WHO CONSENTED TO PARTICIPATE IN THE STUDY WERE RANDOMLY ALLOCATED INTO TWO GROUPS. THE YOGA (Y) GROUP PRACTISED AN INTEGRATED YOGA MODULE THAT INCLUDED ASANAS, PRANAYAMA, MEDITATION, NOTIONAL CORRECTION, AND DEVOTIONAL SESSIONS. THE COMPARISON GROUP PRACTISED MILD TO MODERATE PHYSICAL EXERCISES (PE). BOTH GROUPS HAD SUPERVISED PRACTICES FOR ONE HOUR DAILY, SIX DAYS A WEEK, FOR EIGHT WEEKS. GUNA (PERSONALITY) WAS ASSESSED BEFORE AND AFTER EIGHT WEEKS USING THE SELF-ADMINISTERED "THE 'GITA" INVENTORY OF PERSONALITY" (GIN) TO ASSESS SATTVA, RAJAS, AND TAMAS. SELF ESTEEM IN TERMS OF COMPETENCY (COM), GLOBAL SELF ESTEEM (GSE), MORAL AND SELF ESTEEM (MSE), SOCIAL ESTEEM (SET), FAMILY SELF ESTEEM (FSE), BODY AND PHYSICAL APPEARANCE (BPA), AND THE LIE SCALE (LIS) WERE ASSESSED USING THE SELF ESTEEM QUESTIONNAIRE (SEQ). RESULTS: THE BASELINE SCORES FOR ALL DOMAINS FOR BOTH THE GROUPS DID NOT DIFFER SIGNIFICANTLY (P > 0.05 INDEPENDENT SAMPLES T-TEST). THERE WERE SIGNIFICANT PRE-POST IMPROVEMENTS IN ALL DOMAINS IN BOTH GROUPS (P < 0.001 PAIRED T-TEST). THE NUMBER OF PERSONS WHO SHOWED IMPROVEMENT IN SATTVA AND DECREASE IN TAMAS WAS SIGNIFICANT IN THE Y BUT NOT IN THE PE GROUP (MCNEMAR TEST). THE EFFECT SIZE FOR SELF ESTEEM IN THE Y GROUP IS GREATER THAN FOR THE PE GROUP IN THREE OUT OF SEVEN DOMAINS. CONCLUSIONS: THIS RANDOMIZED CONTROLLED STUDY HAS SHOWN THE INFLUENCE OF YOGA ON GUNAS AND SELF ESTEEM IN COMPARISON TO PHYSICAL EXERCISE.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                     
8  163  29 A RANDOMIZED CONTROL TRIAL OF THE EFFECT OF YOGA ON GUNAS (PERSONALITY) AND HEALTH IN NORMAL HEALTHY VOLUNTEERS. OBJECTIVE: TO STUDY THE EFFICACY OF YOGA ON GUNA (YOGIC PERSONALITY MEASURE) AND GENERAL HEALTH IN NORMAL ADULTS. METHODS: OF THE 1228 PERSONS WHO ATTENDED INTRODUCTORY LECTURES, 226 SUBJECTS AGED 18-71 YEARS, OF BOTH SEXES, WHO SATISFIED THE INCLUSION AND EXCLUSION CRITERIA AND WHO CONSENTED TO PARTICIPATE IN THE STUDY WERE RANDOMLY ALLOCATED INTO TWO GROUPS. THE YOGA(Y) GROUP PRACTISED AN INTEGRATED YOGA MODULE THAT INCLUDED ASANAS, PRANAYAMA, MEDITATION, NOTIONAL CORRECTION AND DEVOTIONAL SESSIONS. THE CONTROL GROUP PRACTISED MILD TO MODERATE PHYSICAL EXERCISES (PE). BOTH GROUPS HAD SUPERVISED PRACTICE SESSIONS (BY TRAINED EXPERTS) FOR ONE HOUR DAILY, SIX DAYS A WEEK FOR EIGHT WEEKS. GUNA (YOGIC PERSONALITY) WAS ASSESSED BEFORE AND AFTER EIGHT WEEKS USING THE SELF-ADMINISTERED VEDIC PERSONALITY INVENTORY (VPI) WHICH ASSESSES SATTVA (GENTLE AND CONTROLLED), RAJAS (VIOLENT AND UNCONTROLLED) AND TAMAS (DULL AND UNCONTROLLED). THE GENERAL HEALTH STATUS (TOTAL HEALTH), WHICH INCLUDES FOUR DOMAINS NAMELY SOMATIC SYMPTOMS (SS), ANXIETY AND INSOMNIA (AI), SOCIAL DYSFUNCTION (SF) AND SEVERE DEPRESSION (SP), WAS ASSESSED USING A GENERAL HEALTH QUESTIONNAIRE (GHQ). RESULTS: BASELINE SCORES FOR ALL THE DOMAINS FOR BOTH THE GROUPS DID NOT DIFFER SIGNIFICANTLY (P > 0.05, INDEPENDENT SAMPLES T TEST). SATTVA SHOWED A SIGNIFICANT DIFFERENCE WITHIN THE GROUPS AND THE EFFECT SIZE WAS MORE IN THE Y THAN IN THE PE GROUP. RAJAS SHOWED A SIGNIFICANT DECREASE WITHIN AND BETWEEN THE GROUPS WITH A HIGHER EFFECT SIZE IN THE PE GROUP. TAMAS SHOWED SIGNIFICANT REDUCTION WITHIN THE PE GROUP ONLY. THE GHQ REVEALED THAT THERE WAS SIGNIFICANT DECREASE IN SS, AI, SF AND SP IN BOTH Y AND PE GROUPS (WILCOXCON SINGED RANK T TEST). SS SHOWED A SIGNIFICANT DIFFERENCE BETWEEN THE GROUPS (MANN WHITNEY U TEST). CONCLUSIONS: THERE WAS AN IMPROVEMENT IN SATTVA IN BOTH THE YOGA AND CONTROL GROUPS WITH A TREND OF HIGHER EFFECT SIZE IN YOGA; RAJAS REDUCED IN BOTH BUT SIGNIFICANTLY BETTER IN PE THAN IN YOGA AND TAMAS REDUCED IN PE. THE GENERAL HEALTH STATUS IMPROVED IN BOTH THE YOGA AND CONTROL GROUPS.	2008	
                                                                         
9 1578  24 MEASUREMENT OF THE EFFECT OF ISHA YOGA ON CARDIAC AUTONOMIC NERVOUS SYSTEM USING SHORT-TERM HEART RATE VARIABILITY. BACKGROUND: BENEFICIAL EFFECTS OF YOGA HAVE BEEN POSTULATED TO BE DUE TO MODULATION OF THE AUTONOMIC NERVOUS SYSTEM. OBJECTIVE: TO ASSESS THE EFFECT OF ISHA YOGA PRACTICES ON CARDIOVASCULAR AUTONOMIC NERVOUS SYSTEM THROUGH SHORT-TERM HEART RATE VARIABILITY (HRV). DESIGN OF THE STUDY: SHORT-TERM HRV OF LONG-TERM REGULAR HEALTHY 14 (12 MALES AND 2 FEMALES) ISHA YOGA PRACTITIONERS WAS COMPARED WITH THAT OF AGE- AND GENDER-MATCHED 14 (12 MALES AND 2 FEMALES) NON-YOGA PRACTITIONERS. METHODS AND MATERIALS: ECG LEAD II AND RESPIRATORY MOVEMENTS WERE RECORDED IN BOTH GROUPS USING POLYRITE DURING SUPINE REST FOR 5 MIN AND CONTROLLED DEEP BREATHING FOR 1 MINUTE. FREQUENCY DOMAIN ANALYSIS [RR INTERVAL IS THE MEAN OF DISTANCE BETWEEN SUBSEQUENT R WAVE PEAKS IN ECG], LOW FREQUENCY (LF) POWER, HIGH FREQUENCY (HF) POWER, LF NORMALIZED UNITS (NU), HF NU, LF/HF RATIO] AND TIME DOMAIN ANALYSIS [STANDARD DEVIATION OF NORMAL TO NORMAL INTERVAL (SDNN), SQUARE OF MEAN SQUARED DIFFERENCE OF SUCCESSIVE NORMAL TO NORMAL INTERVALS (RMSSD), NORMAL TO NORMAL INTERVALS WHICH ARE DIFFERING BY 50 MS (NN50), AND PERCENTAGE OF NN50 (PNN50)] OF HRV VARIABLES WERE ANALYZED FOR SUPINE REST. TIME DOMAIN ANALYSIS WAS RECORDED FOR DEEP BREATHING. RESULTS: RESULTS SHOWED STATISTICALLY SIGNIFICANT DIFFERENCES BETWEEN ISHA YOGA PRACTITIONERS AND CONTROLS IN BOTH FREQUENCY AND TIME DOMAIN ANALYSES OF HRV INDICES, WITH NO DIFFERENCE IN RESTING HEART RATE BETWEEN THE GROUPS. CONCLUSIONS: PRACTITIONERS OF ISHA YOGA SHOWED WELL-BALANCED BENEFICIAL ACTIVITY OF VAGAL EFFERENTS, AN OVERALL INCREASED HRV, AND SYMPATHOVAGAL BALANCE, COMPARED TO NON-YOGA PRACTITIONERS DURING SUPINE REST AND DEEP BREATHING.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
10  350  27 ASSESSMENT OF CARDIAC AUTONOMIC TONE FOLLOWING LONG SUDARSHAN KRIYA YOGA IN ART OF LIVING PRACTITIONERS. OBJECTIVE: THE BREATHING PROCESSES ARE KNOWN TO MODULATE CARDIAC AUTONOMIC TONE AND IMPROVE PSYCHOLOGICAL STATUS. WE INVESTIGATED CARDIAC AUTONOMIC TONE FOLLOWING LONG SUDARSHAN KRIYA YOGA (SKY) USING HEART RATE VARIABILITY (HRV) AND SKIN CONDUCTANCE LEVEL (SCL). METHODS: THIRTY HEALTHY VOLUNTEERS (AGE 28.3 +/- 8.4 YEARS; 23 M: 7 F) PARTICIPATED IN THE STUDY. ELECTROCARDIOGRAM (ECG) AND SCL WERE RECORDED FOR 5 MIN EACH, BEFORE AND AFTER LONG SKY. LONG SKY IS A COMBINATION OF PRANAYAMA AND CYCLIC RHYTHMIC BREATHING AND IS PERFORMED BY FOLLOWING THE GUIDED AUDIO INSTRUCTIONS. HRV ANALYSIS WAS USED FOR THE ASSESSMENT OF CARDIAC AUTONOMIC TONE. TIME AND FREQUENCY DOMAIN PARAMETERS OF HRV WERE CALCULATED BY USING RR INTERVAL OF ECG. SCL WAS ACQUIRED USING GALVANIC SKIN RESPONSE (GSR) AMPLIFIER OF POWERLAB IN MICROSEIMENS (MUS). RESULTS: TIME DOMAIN PARAMETERS OF HRV, INCLUDING MEAN RR INTERVAL (P = 0.000), RESPIRATORY SINUS ARRHYTHMIA (RSA) (P = 0.037), STANDARD DEVIATION OF ALL NN INTERVALS (SDNN) (P = 0.013), NN50 COUNT DIVIDED BY THE TOTAL NUMBER OF ALL NN INTERVALS (PNN50) (P = 0.004), AND SQUARE ROOT OF THE MEAN OF THE SUM OF THE SQUARES OF DIFFERENCES BETWEEN ADJACENT NN INTERVALS (RMSSD) (P = 0.002) INCREASED, AND MEAN HEART RATE DECREASED (P = 0.000) FOLLOWING LONG SKY. IN FREQUENCY DOMAIN ANALYSIS, POWER OF LOW-FREQUENCY (LF) COMPONENT (P = 0.010) AND LF/HF RATIO (P = 0.008) DECREASED SIGNIFICANTLY, WHEREAS POWER OF HIGH FREQUENCY (HF) SIGNIFICANTLY INCREASED (P = 0.010). SCL DECREASED FOLLOWING LONG SKY, ALTHOUGH IT DID NOT ATTAIN STATISTICAL SIGNIFICANCE. CONCLUSIONS: THE RESULTS SUGGEST THAT LONG SKY INDUCES SIGNIFICANT OSCILLATIONS IN CARDIAC AUTONOMIC TONE. PARASYMPATHETIC ACTIVITY INCREASES AND SYMPATHETIC ACTIVITY DECREASES AND SYMPATHOVAGAL BALANCE IMPROVES FOLLOWING LONG SKY. DECREASE IN SYMPATHETIC ACTIVITY IS ALSO DEMONSTRATED BY DECREASE IN CONDUCTANCE ALTHOUGH IT DID NOT REACH STATISTICAL SIGNIFICANCE. FROM THIS STUDY IT CAN BE CONCLUDED THAT LONG SKY HAS A BENEFICIAL EFFECT ON CARDIAC AUTONOMIC TONE, AND PSYCHOPHYSIOLOGICAL RELAXATION. IT MAY SERVE AS A TOOL TO IMPROVE HRV, WHICH IS THE MARKER OF CARDIOVASCULAR HEALTH.	2017	

11 1441  19 INCREASED HEART RATE VARIABILITY BUT NO EFFECT ON BLOOD PRESSURE FROM 8 WEEKS OF HATHA YOGA - A PILOT STUDY. BACKGROUND: YOGA EXERCISES ARE KNOWN TO DECREASE STRESS AND RESTORE AUTONOMIC BALANCE. YET KNOWLEDGE ABOUT THE PHYSIOLOGICAL EFFECTS OF INVERSION POSTURES IS LIMITED. THIS STUDY AIMED TO INVESTIGATE THE EFFECTS OF INVERSION POSTURES (HEAD BELOW THE HEART) ON BLOOD PRESSURE (BP) AND HEART RATE VARIABILITY (HRV). METHODS: TWELVE HEALTHY WOMEN AND MEN TOOK PART IN AN 8-WEEK YOGA PROGRAM (60 MIN ONCE A WEEK). BP WAS MEASURED WITH AN AUTOMATIC OMRON MX3 OSCILLOMETRIC MONITORING DEVICE AND HRV WITH A HOLTER 24-HOUR ECG AT BASELINE AND 8 WEEKS AFTER THE INTERVENTION. RESULTS: THERE WAS NO SIGNIFICANT EFFECT OF INVERSION POSTURES ON BP. NINE OUT OF 12 PARTICIPANTS SHOWED A SIGNIFICANT INCREASE IN HRV (P < 0.05) AT NIGHT (2 HOURS) ON PNN50% (12.7 +/- 12.5 TO 18.2 +/- 13.3). THERE WERE NO SIGNIFICANT CHANGES IN OTHER HRV MEASURES SUCH AS NN50, LF, HF, LF/HF RATIO, LF NORMALIZED UNITS (N.U.), HF N.U. AND RMSSD. CONCLUSION: EIGHT WEEKS OF HATHA YOGA IMPROVED HRV SIGNIFICANTLY WHICH SUGGESTS AN INCREASED VAGAL TONE AND REDUCED SYMPATHETIC ACTIVITY.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
12 1318  19 HEART RATE VARIABILITY IN CHRONIC LOW BACK PAIN PATIENTS RANDOMIZED TO YOGA OR STANDARD CARE. BACKGROUND: CHRONIC PAIN CAN ALTER THE AUTONOMIC BALANCE WITH INCREASED SYMPATHETIC ACTIVITY REFLECTED IN ALTERED HEART RATE VARIABILITY (HRV). IT HAS BEEN PROPOSED THAT YOGA CAN BE USEFUL TO CORRECT THE AUTONOMIC IMBALANCE IN PATIENTS WITH CHRONIC PAIN WHO HAVE REDUCED HRV. METHODS AND DESIGNS: IN THE PRESENT RANDOMIZED CONTROLLED TRIAL 62 PATIENTS WITH CHRONIC LOW BACK PAIN ASSOCIATED WITH ALTERED ALIGNMENT OF INTERVERTEBRAL DISCS (AGED BETWEEN 20 AND 45 YEARS, 32 MALES) WERE RANDOMIZED TO 2 GROUPS. ONE GROUP RECEIVED YOGA FOR 3 MONTHS WHILE THE OTHER GROUP CARRIED OUT STANDARD MEDICAL CARE BASED ON THE PHYSICIAN'S ADVICE. THE DURATION WAS THE SAME, I.E., 3 MONTHS. THE HEART RATE VARIABILITY AND RATE OF RESPIRATION WERE ASSESSED AT BASELINE AND AT THE END OF 3 MONTHS. RESULTS: THERE WAS A SIGNIFICANT DIFFERENCE IN THE BASELINE (PRE) VALUES BETWEEN GROUPS (P = 0.008) FOR RESPIRATION RATE WHICH WAS HIGHER IN THE YOGA GROUP. THE CHANGES REPORTED BELOW ARE PRE-POST COMPARISONS WITHIN EACH GROUP. THE YOGA GROUP SHOWED A SIGNIFICANT (P < 0.05; REPEATED MEASURES ANOVA, POST-HOC ANALYSES) DECREASE IN THE LF POWER OF HRV, RATE OF RESPIRATION AND A SIGNIFICANT INCREASE IN THE HF POWER OF HRV AND IN THE PNN50. CONCLUSION: THE RESULTS SUGGEST THAT YOGA PRACTICE CAN SHIFT THE AUTONOMIC BALANCE TOWARDS VAGAL DOMINANCE IN PATIENTS WITH CHRONIC LOW BACK PAIN ASSOCIATED WITH ALTERED ALIGNMENT OF INTERVERTEBRAL DISCS. TRIAL REGISTRATION: THE STUDY IS REGISTERED WITH THE CLINICAL TRIALS REGISTRY OF INDIA ( CTRI/2012/11/003094 ) AND CAN BE ACCESSED AT.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
13  243  28 A YOGA & EXERCISE RANDOMIZED CONTROLLED TRIAL FOR VASOMOTOR SYMPTOMS: EFFECTS ON HEART RATE VARIABILITY. OBJECTIVES: HEART RATE VARIABILITY (HRV) REFLECTS THE INTEGRATION OF THE PARASYMPATHETIC NERVOUS SYSTEM WITH THE REST OF THE BODY. STUDIES ON THE EFFECTS OF YOGA AND EXERCISE ON HRV HAVE BEEN MIXED BUT SUGGEST THAT EXERCISE INCREASES HRV. WE CONDUCTED A SECONDARY ANALYSIS OF THE EFFECT OF YOGA AND EXERCISE ON HRV BASED ON A RANDOMIZED CLINICAL TRIAL OF TREATMENTS FOR VASOMOTOR SYMPTOMS IN PERI/POST-MENOPAUSAL WOMEN. DESIGN: RANDOMIZED CLINICAL TRIAL OF BEHAVIORAL INTERVENTIONS IN WOMEN WITH VASOMOTOR SYMPTOMS (N=335), 40-62 YEARS OLD FROM THREE CLINICAL STUDY SITES. INTERVENTIONS: 12-WEEKS OF A YOGA PROGRAM, DESIGNED SPECIFICALLY FOR MID-LIFE WOMEN, OR A SUPERVISED AEROBIC EXERCISE-TRAINING PROGRAM WITH SPECIFIC INTENSITY AND ENERGY EXPENDITURE GOALS, COMPARED TO A USUAL ACTIVITY GROUP. MAIN OUTCOME MEASURES: TIME AND FREQUENCY DOMAIN HRV MEASURED AT BASELINE AND AT 12 WEEKS FOR 15MIN USING HOLTER MONITORS. RESULTS: WOMEN HAD A MEDIAN OF 7.6 VASOMOTOR SYMPTOMS PER 24H. TIME AND FREQUENCY DOMAIN HRV MEASURES DID NOT CHANGE SIGNIFICANTLY IN EITHER OF THE INTERVENTION GROUPS COMPARED TO THE CHANGE IN THE USUAL ACTIVITY GROUP. HRV RESULTS DID NOT DIFFER WHEN THE ANALYSES WERE RESTRICTED TO POST-MENOPAUSAL WOMEN. CONCLUSIONS: ALTHOUGH YOGA AND EXERCISE HAVE BEEN SHOWN TO INCREASE PARASYMPATHETIC-MEDIATED HRV IN OTHER POPULATIONS, NEITHER INTERVENTION INCREASED HRV IN MIDDLE-AGED WOMEN WITH VASOMOTOR SYMPTOMS. MIXED RESULTS IN PREVIOUS RESEARCH MAY BE DUE TO SAMPLE DIFFERENCES. YOGA AND EXERCISE LIKELY IMPROVE SHORT-TERM HEALTH IN MIDDLE-AGED WOMEN THROUGH MECHANISMS OTHER THAN HRV.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
14  297  21 ALTERNATE NOSTRIL BREATHING AT DIFFERENT RATES AND ITS INFLUENCE ON HEART RATE VARIABILITY IN NON PRACTITIONERS OF YOGA. INTRODUCTION: HEART RATE VARIABILITY IS A MEASURE OF MODULATION IN AUTONOMIC INPUT TO THE HEART AND IS ONE OF THE MARKERS OF AUTONOMIC FUNCTIONS. THOUGH THERE ARE MANY STUDIES ON THE LONG TERM INFLUENCE OF BREATHING ON HRV (HEART RATE VARIABILITY) THERE ARE ONLY A FEW STUDIES ON THE IMMEDIATE EFFECT OF BREATHING ESPECIALLY ALTERNATE NOSTRIL BREATHING ON HRV. THIS STUDY FOCUSES ON THE IMMEDIATE EFFECTS OF ALTERNATE NOSTRIL BREATHING AND THE INFLUENCE OF DIFFERENT BREATHING RATES ON HRV. MATERIALS AND METHODS: THE STUDY WAS DONE ON 25 SUBJECTS IN THE AGE GROUP OF 17-35 YEARS. ECG AND RESPIRATION WERE RECORDED BEFORE INTERVENTION AND IMMEDIATELY AFTER THE SUBJECTS WERE ASKED TO PERFORM ALTERNATE NOSTRIL BREATHING FOR FIVE MINUTES. RESULTS: LOW FREQUENCY (LF) WHICH IS A MARKER OF SYMPATHETIC ACTIVITY INCREASED, HIGH FREQUENCY (HF) WHICH IS A MARKER OF PARASYMPATHETIC ACTIVITY DECREASED AND THEIR RATIO LF/HF WHICH IS A MARKER OF SYMPATHO/VAGAL BALANCE INCREASED IMMEDIATELY AFTER 6 AND 12 MINUTES IN COMPARISON TO BASELINE VALUES WHEREAS THERE WAS NO SIGNIFICANT DIFFERENCE IN THE MEANS OF THESE COMPONENTS WHEN BOTH 6 AND 12 MINUTES WERE COMPARED. CONCLUSION: IMMEDIATE EFFECTS OF ALTERNATE NOSTRIL BREATHING ON HRV IN NON PRACTITIONERS OF YOGIC BREATHING ARE VERY DIFFERENT FROM THE LONG TERM INFLUENCE OF YOGIC BREATHING ON HRV WHICH SHOW A PREDOMINANT PARASYMPATHETIC INFLUENCE ON THE HEART.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
15  452  21 CHANGES IN HEART RATE VARIABILITY AFTER YOGA ARE DEPENDENT ON HEART RATE VARIABILITY AT BASELINE AND DURING YOGA: A STUDY SHOWING AUTONOMIC NORMALIZATION EFFECT IN YOGA-NAIVE AND EXPERIENCED SUBJECTS. BACKGROUND: YOGA THERAPY IS WIDELY APPLIED TO THE MAINTENANCE OF HEALTH AND TO TREATMENT OF VARIOUS ILLNESSES. PREVIOUS RESEARCHES INDICATE THE INVOLVEMENT OF AUTONOMIC CONTROL IN ITS EFFECTS, ALTHOUGH THE GENERAL AGREEMENT HAS NOT BEEN REACHED REGARDING THE ACUTE MODULATION OF AUTONOMIC FUNCTION. AIM: THE PRESENT STUDY AIMED AT REVEALING THE ACUTE EFFECT OF YOGA ON THE AUTONOMIC ACTIVITY USING HEART RATE VARIABILITY (HRV) MEASUREMENT. METHODS: TWENTY-SEVEN HEALTHY CONTROLS PARTICIPATED IN THE PRESENT STUDY. FIFTEEN OF THEM (39.5 +/- 8.5 YEARS OLD) WERE NAIVE AND 12 (45.1 +/- 7.0 YEARS OLD) WERE EXPERIENCED IN YOGA. YOGA SKILLS INCLUDED BREATH AWARENESS, TWO TYPES OF ASANA, AND TWO TYPES OF PRANAYAMA. HRV WAS MEASURED AT THE BASELINE, DURING YOGA, AND AT THE RESTING STATE AFTER YOGA. RESULTS: IN BOTH YOGA-NAIVE AND EXPERIENCED PARTICIPANTS, THE CHANGES IN LOW-FREQUENCY (LF) COMPONENT OF HRV AND ITS RATIO TO HIGH-FREQUENCY (HF) COMPONENT (LF/HF) AFTER YOGA WERE FOUND TO BE CORRELATED NEGATIVELY WITH THE BASELINE DATA. THE CHANGES IN LF AFTER YOGA WERE ALSO CORRELATED WITH LF DURING YOGA. THE CHANGES IN HF AS WELL AS THE RAW HRV DATA AFTER YOGA WERE NOT RELATED TO THE BASELINE HRV OR THE HRV DURING YOGA. CONCLUSION: THE RESULTS INDICATE THAT YOGA LEADS TO AN INCREASE IN LF WHEN LF IS LOW AND LEADS TO A DECREASE IN LF WHEN IT IS HIGH AT THE BASELINE. THIS NORMALIZATION OF LF IS DEPENDENT ON THE AUTONOMIC MODULATION DURING YOGA AND MAY UNDERLIE THE CLINICAL EFFECTIVENESS OF YOGA THERAPY BOTH IN YOGA-NAIVE AND EXPERIENCED SUBJECTS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
16 1530  23 IYENGAR YOGA INCREASES CARDIAC PARASYMPATHETIC NERVOUS MODULATION AMONG HEALTHY YOGA PRACTITIONERS. RELAXATION TECHNIQUES ARE ESTABLISHED IN MANAGING OF CARDIAC PATIENTS DURING REHABILITATION AIMING TO REDUCE FUTURE ADVERSE CARDIAC EVENTS. IT HAS BEEN HYPOTHESIZED THAT RELAXATION-TRAINING PROGRAMS MAY SIGNIFICANTLY IMPROVE CARDIAC AUTONOMIC NERVOUS TONE. HOWEVER, THIS HAS NOT BEEN PROVEN FOR ALL AVAILABLE RELAXATION TECHNIQUES. WE TESTED THIS ASSUMPTION BY INVESTIGATING CARDIAC VAGAL MODULATION DURING YOGA.WE EXAMINED 11 HEALTHY YOGA PRACTITIONERS (7 WOMEN AND 4 MEN, MEAN AGE: 43 +/- 11; RANGE: 26-58 YEARS). EACH INDIVIDUAL WAS SUBJECTED TO TRAINING UNITS OF 90 MIN ONCE A WEEK OVER FIVE SUCCESSIVE WEEKS. DURING TWO SESSIONS, THEY PRACTICED A YOGA PROGRAM DEVELOPED FOR CARDIAC PATIENTS BY B.K.S. IYENGAR. ON THREE SESSIONS, THEY PRACTICED A PLACEBO PROGRAM OF RELAXATION. ON EACH TRAINING DAY THEY UNDERWENT AMBULATORY 24 H HOLTER MONITORING. THE GROUP OF YOGA PRACTITIONERS WAS COMPARED TO A MATCHED GROUP OF HEALTHY INDIVIDUALS NOT PRACTICING ANY RELAXATION TECHNIQUES. PARAMETERS OF HEART RATE VARIABILITY (HRV) WERE DETERMINED HOURLY BY A BLINDED OBSERVER. MEAN RR INTERVAL (INTERVAL BETWEEN TWO R-WAVES OF THE ECG) WAS SIGNIFICANTLY HIGHER DURING THE TIME OF YOGA INTERVENTION COMPARED TO PLACEBO AND TO CONTROL (P < 0.001 FOR BOTH). THE INCREASE IN HRV PARAMETERS WAS SIGNIFICANTLY HIGHER DURING YOGA EXERCISE THAN DURING PLACEBO AND CONTROL ESPECIALLY FOR THE PARAMETERS ASSOCIATED WITH VAGAL TONE, I.E. MEAN STANDARD DEVIATION OF NN (NORMAL BEAT TO NORMAL BEAT OF THE ECG) INTERVALS FOR ALL 5-MIN INTERVALS (SDNNI, P < 0.001 FOR BOTH) AND ROOT MEAN SQUARE SUCCESSIVE DIFFERENCE (RMSSD, P < 0.01 FOR BOTH). IN CONCLUSION, RELAXATION BY YOGA TRAINING IS ASSOCIATED WITH A SIGNIFICANT INCREASE OF CARDIAC VAGAL MODULATION. SINCE THIS METHOD IS EASY TO APPLY WITH NO SIDE EFFECTS, IT COULD BE A SUITABLE INTERVENTION IN CARDIAC REHABILITATION PROGRAMS.	2007	
                                                                                                                                                                                                                                                                                                                         
17  448  28 CHANGES IN AUTONOMIC VARIABLES FOLLOWING TWO MEDITATIVE STATES DESCRIBED IN YOGA TEXTS. OBJECTIVES: IN ANCIENT YOGA TEXTS THERE ARE TWO MEDITATIVE STATES DESCRIBED. ONE IS DHARANA, WHICH REQUIRES FOCUSING, THE SECOND IS DHYANA, DURING WHICH THERE IS NO FOCUSING, BUT AN EXPANSIVE MENTAL STATE IS REACHED. WHILE AN EARLIER STUDY DID SHOW IMPROVED PERFORMANCE IN AN ATTENTION TASK AFTER DHARANA, THE AUTONOMIC CHANGES DURING THESE TWO STATES HAVE NOT BEEN STUDIED. METHODS: AUTONOMIC AND RESPIRATORY VARIABLES WERE ASSESSED IN 30 HEALTHY MALE VOLUNTEERS (GROUP MEAN AGE +/- SD, 29.1 +/- 5.1 YEARS) DURING FOUR MENTAL STATES DESCRIBED IN TRADITIONAL YOGA TEXTS. THESE FOUR MENTAL STATES ARE RANDOM THINKING (CANCALATA), NONMEDITATIVE FOCUSING (EKAGRATA), MEDITATIVE FOCUSING (DHARANA), AND EFFORTLESS MEDITATION (DHYANA). ASSESSMENTS WERE MADE BEFORE (5 MINUTES), DURING (20 MINUTES), AND AFTER (5 MINUTES), EACH OF THE FOUR STATES, ON FOUR SEPARATE DAYS. RESULTS: DURING DHYANA THERE WAS A SIGNIFICANT INCREASE IN THE SKIN RESISTANCE LEVEL (P<0.001; POST HOC ANALYSIS FOLLOWING ANOVA, DURING COMPARED TO PRE) AND PHOTO-PLETHYSMOGRAM AMPLITUDE (P<0.05), WHEREAS THERE WAS A SIGNIFICANT DECREASE IN THE HEART RATE (P<0.001) AND BREATH RATE (P<0.001). THERE WAS A SIGNIFICANT DECREASE IN THE LOW FREQUENCY (LF) POWER (P<0.001) AND INCREASE IN THE HIGH FREQUENCY (HF) POWER (P<0.001) IN THE FREQUENCY DOMAIN ANALYSIS OF THE HEART RATE VARIABILITY (HRV) SPECTRUM, ON WHICH HF POWER IS ASSOCIATED WITH PARASYMPATHETIC ACTIVITY. THERE WAS ALSO A SIGNIFICANT INCREASE IN THE NN50 COUNT (THE NUMBER OF INTERVAL DIFFERENCES OF SUCCESSIVE NN INTERVALS GREATER THAN 50 MS; P<0.001) AND THE PNN50 (THE PROPORTION DERIVED BY DIVIDING NN50 BY THE TOTAL NUMBER OF NN INTERVALS; P<0.001) IN TIME DOMAIN ANALYSIS OF HRV, BOTH INDICATIVE OF PARASYMPATHETIC ACTIVITY. CONCLUSIONS: MAXIMUM CHANGES WERE SEEN IN AUTONOMIC VARIABLES AND BREATH RATE DURING THE STATE OF EFFORTLESS MEDITATION (DHYANA). THE CHANGES WERE ALL SUGGESTIVE OF REDUCED SYMPATHETIC ACTIVITY AND/OR INCREASED VAGAL MODULATION. DURING DHARANA THERE WAS AN INCREASE IN SKIN RESISTANCE. THE CHANGES IN HRV DURING EKAGRATA AND CANCALATA WERE INCONCLUSIVE.	2013	
                                                                                
18  411  24 BLOOD PRESSURE AND HEART RATE VARIABILITY DURING YOGA-BASED ALTERNATE NOSTRIL BREATHING PRACTICE AND BREATH AWARENESS. BACKGROUND: PREVIOUS RESEARCH HAS SHOWN A REDUCTION IN BLOOD PRESSURE (BP) IMMEDIATELY AFTER THE PRACTICE OF ALTERNATE NOSTRIL YOGA BREATHING (ANYB) IN NORMAL HEALTHY MALE VOLUNTEERS AND IN HYPERTENSIVE PATIENTS OF BOTH SEXES. THE BP DURING ANYB HAS NOT BEEN RECORDED. MATERIAL/METHODS: PARTICIPANTS WERE 26 MALE VOLUNTEERS (GROUP MEAN AGE +/-SD, 23.8+/-3.5 YEARS). WE ASSESSED (1) HEART RATE VARIABILITY, (2) NON-INVASIVE ARTERIAL BP, AND (3) RESPIRATION RATE, DURING (A) ANYB AND (B) BREATH AWARENESS (BAW) SESSIONS. EACH SESSION WAS 25 MINUTES. WE PERFORMED ASSESSMENTS AT 3 TIME POINTS: PRE (5 MINUTES), DURING (15 MINUTES; FOR ANYB OR BAW) AND POST (5 MINUTES). A NAIVE-TO-YOGA CONTROL GROUP (N=15 MALES, MEAN AGE +/-SD 26.1+/-4.0 YEARS) WERE ASSESSED WHILE SEATED QUIETLY FOR 25 MINUTES. RESULTS: DURING ANYB THERE WAS A SIGNIFICANT DECREASE (REPEATED MEASURES ANOVA) IN SYSTOLIC BP AND RESPIRATION RATE; WHILE RMSSD (THE SQUARE ROOT OF THE MEAN OF THE SUM OF SQUARES OF DIFFERENCES BETWEEN ADJACENT NN INTERVALS) AND NN50 (THE NUMBER OF INTERVAL DIFFERENCES OF SUCCESSIVE NORMAL TO NORMAL INTERVALS GREATER THAN 50 MS) SIGNIFICANTLY INCREASED. DURING BAW RESPIRATION RATE DECREASED. IN CONTRAST, RESPIRATION RATE INCREASED DURING THE CONTROL STATE. ANYB AND BAW WERE SIGNIFICANTLY DIFFERENT (2-FACTOR ANOVA) IN RMSSD AND RESPIRATION RATE. BAW AND CONTROL WERE DIFFERENT WITH RESPECT TO RESPIRATION RATE. CONCLUSIONS: THE RESULTS SUGGEST THAT VAGAL ACTIVITY INCREASED DURING AND AFTER ANYB, WHICH COULD HAVE CONTRIBUTED TO THE DECREASE IN BP AND CHANGES IN THE HRV.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
19 2731  27 YOGA OFFERS CARDIOVASCULAR PROTECTION IN EARLY POSTMENOPAUSAL WOMEN. CONTEXT: POSTMENOPAUSE, AN ESTROGEN DEFICIENT STATE COMES WITH INCREASED INCIDENCE OF CARDIOVASCULAR DISEASES (CVDS). YOGA HAS BEEN DESCRIBED AS HAVING A BENEFICIAL EFFECT ON HEART RATE VARIABILITY (HRV), A MARKER FOR CARDIAC AUTONOMIC ACTIVITY WHICH CAN ASSESS CARDIOVASCULAR RISK, IN VARIOUS POPULATIONS. AIM: THE AIM OF THE STUDY WAS TO STUDY THE EFFECT OF 3-MONTH LONG YOGA PRACTICE ON HRV IN EARLY POSTMENOPAUSAL WOMEN. SETTINGS AND DESIGN: A PROSPECTIVE LONGITUDINAL STUDY OF 67 WOMEN WITHIN 5 YEARS OF MENOPAUSE BETWEEN 45 AND 60 YEARS OF AGE ATTENDING MENOPAUSE CLINIC OF DEPARTMENT OF GYNAECOLOGY, SUCHETA KRIPLANI HOSPITAL FULFILLING INCLUSION AND EXCLUSION CRITERIA AND CONSENTING WERE ENROLLED FOR THE STUDY. SUBJECTS AND METHODS: HRV OF 37 CASES (YOGA GROUP) AND 30 CONTROLS (NON-YOGA GROUP) WAS RECORDED PRE AND 3-MONTH POSTINTERVENTION. STATISTICAL ANALYSIS USED: GRAPHPAD PRISM VERSION 5 SOFTWARE WAS USED. VALUES ARE A MEAN AND STANDARD ERROR OF MEAN. STATISTICAL SIGNIFICANCE WAS SET UP AT P < 0.05. RESULTS: IN HRV, FREQUENCY DOMAIN ANALYSIS SHOWED A SIGNIFICANT FALL IN LOW FREQUENCY (LF) IN NORMALIZED UNITS (NU) AND LF: HIGH FREQUENCY (HF) RATIO AND SIGNIFICANT RISE IN HF IN NU IN THE YOGA GROUP (DEPICTING PARASYMPATHETIC DOMINANCE) AGAINST A SIGNIFICANT RISE IN LF (NU) AND LF: HF RATIO AND SIGNIFICANT FALL IN HF (NU) IN NON-YOGA GROUP (INDICATING SYMPATHETIC DOMINANCE). TIME DOMAIN ANALYSIS SHOWED A SIGNIFICANT DECREASE IN STANDARD DEVIATION OF NN INTERVALS IN NON-YOGA GROUP AGAINST NONSIGNIFICANT CHANGES IN YOGA GROUP INDICATING DETERIORATION IN PARASYMPATHETIC ACTIVITY IN NON-YOGA GROUP. CONCLUSIONS: THREE-MONTH LONG YOGA PRACTICE IMPROVED HRV IN EARLY POSTMENOPAUSAL WOMEN SIGNIFICANTLY AND HAS THE POTENTIAL TO ATTENUATE THE CVD RISK IN POSTMENOPAUSAL WOMEN.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                               
20  165  31 A RANDOMIZED CONTROL TRIAL OF THE EFFECT OF YOGA ON VERBAL AGGRESSIVENESS IN NORMAL HEALTHY VOLUNTEERS. OBJECTIVE: TO STUDY THE EFFECT OF YOGA ON VERBAL AGGRESSIVENESS IN NORMAL HEALTHY ADULTS. METHODS: OF THE 1228 PERSONS WHO ATTENDED INTRODUCTORY LECTURES, 226 SUBJECTS OF BOTH SEXES WHO SATISFIED THE INCLUSION AND EXCLUSION CRITERIA AND WHO CONSENTED TO PARTICIPATE IN THE STUDY WERE RANDOMLY ALLOCATED INTO TWO GROUPS. THESE 226 SUBJECTS WERE BETWEEN THE AGES OF 17 AND 62 YEARS AND 173/226 COMPLETED THE EIGHT WEEKS OF INTERVENTION. THE YOGA (Y) GROUP PRACTISED AN INTEGRATED YOGA MODULE THAT INCLUDED ASANAS, PRANAYAMA, MEDITATION, NOTIONAL CORRECTION, AND DEVOTIONAL SESSIONS. THE CONTROL GROUP PRACTISED MILD TO MODERATE PHYSICAL EXERCISES (PE). BOTH GROUPS HAD SUPERVISED PRACTICES (BY TRAINED EXPERTS) FOR ONE HOUR DAILY, SIX DAYS A WEEK FOR EIGHT WEEKS. VERBAL AGGRESSIVENESS WAS ASSESSED BEFORE AND AFTER EIGHT WEEKS USING THE SELF-ADMINISTERED VERBAL AGGRESSIVE SCALE. RESULTS: THE BASELINE SCORE OF THE TWO GROUPS DID NOT DIFFER SIGNIFICANTLY (P = 0.66). THERE WAS A SIGNIFICANT DECREASE IN VERBAL AGGRESSIVENESS IN THE YOGA GROUP (P = 0.01 PAIRED SAMPLES T-TEST) WITH A NONSIGNIFICANT INCREASE IN THE PE GROUP. ANCOVA USING PRE- VALUES AS COVARIATES SHOWED A SIGNIFICANT DIFFERENCE BETWEEN THE GROUPS (P = 0.013). RMANOVA FOR INTERACTION BETWEEN THE SEXES OR AGE GROUPS IN CHANGE SCORES WERE NOT SIGNIFICANT. CONCLUSIONS: THIS STUDY HAS DEMONSTRATED THAT AN EIGHT WEEK INTERVENTION OF AN INTEGRATED YOGA MODULE DECREASED VERBAL AGGRESSIVENESS IN THE YOGA GROUP (IN MALES AND THOSE BELOW 25 YEARS OF AGE), WITH A NONSIGNIFICANT INCREASE IN THE PE GROUP.	2008