1 1881 136 REDUCED HYPOXIC VENTILATORY RESPONSE WITH PRESERVED BLOOD OXYGENATION IN YOGA TRAINEES AND HIMALAYAN BUDDHIST MONKS AT ALTITUDE: EVIDENCE OF A DIFFERENT ADAPTIVE STRATEGY? YOGA INDUCES LONG-TERM CHANGES IN RESPIRATORY FUNCTION AND CONTROL. WE TESTED WHETHER IT REPRESENTS A SUCCESSFUL STRATEGY FOR HIGH-ALTITUDE ADAPTATION. WE COMPARED VENTILATORY, CARDIOVASCULAR AND HEMATOLOGICAL PARAMETERS IN: 12 CAUCASIAN YOGA TRAINEES AND 12 CONTROL SEA-LEVEL RESIDENTS, AT BASELINE AND AFTER 2-WEEK EXPOSURE TO HIGH ALTITUDE (PYRAMID LABORATORY, NEPAL, 5,050 M), 38 ACTIVE LIFESTYLE HIGH-ALTITUDE NATIVES (SHERPAS) AND 13 CONTEMPLATIVE LIFESTYLE HIGH-ALTITUDE NATIVES WITH PRACTICE OF YOGA-LIKE RESPIRATORY EXERCISES (BUDDHIST MONKS) STUDIED AT 5,050 M. AT BASELINE, HYPOXIC VENTILATORY RESPONSE (HVR), RED BLOOD CELL COUNT AND HEMATOCRIT WERE LOWER IN CAUCASIAN YOGA TRAINEES THAN IN CONTROLS. AFTER 14 DAYS AT ALTITUDE, YOGA TRAINEES SHOWED SIMILAR OXYGEN SATURATION, BLOOD PRESSURE, RR INTERVAL COMPARED TO CONTROLS, BUT LOWER HVR (-0.44 +/- 0.08 VS. -0.98 +/- 0.21 L/MIN/M/%SAO(2), P < 0.05), MINUTE VENTILATION (8.3 +/- 0.9 VS. 10.8 +/- 1.6 L/MIN, P < 0.05), BREATHING RATE (INDICATING HIGHER VENTILATORY EFFICIENCY), AND LOWER RED BLOOD CELL COUNT, HEMOGLOBIN, HEMATOCRIT, ALBUMIN, ERYTHROPOIETIN AND SOLUBLE TRANSFERRIN RECEPTORS. HYPOXIC VENTILATORY RESPONSE IN MONKS WAS LOWER THAN IN SHERPAS (-0.23 +/- 0.05 VS. -0.63 +/- 0.09 L/MIN/M/%SAO(2), P < 0.05); VALUES WERE SIMILAR TO BASELINE DATA OF YOGA TRAINEES AND CAUCASIAN CONTROLS, RESPECTIVELY. RED BLOOD CELL COUNT AND HEMATOCRIT WERE LOWER IN MONKS AS COMPARED TO SHERPAS. IN CONCLUSION, CAUCASIAN SUBJECTS PRACTICING YOGA MAINTAIN A SATISFACTORY OXYGEN TRANSPORT AT HIGH ALTITUDE, WITH MINIMAL INCREASE IN VENTILATION AND WITH REDUCED HEMATOLOGICAL CHANGES, RESEMBLING HIMALAYAN NATIVES. RESPIRATORY ADAPTATIONS INDUCED BY THE PRACTICE OF YOGA MAY REPRESENT AN EFFICIENT STRATEGY TO COPE WITH ALTITUDE-INDUCED HYPOXIA.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
2 2744  41 YOGA PRACTICE IMPROVES PHYSIOLOGICAL AND BIOCHEMICAL STATUS AT HIGH ALTITUDES: A PROSPECTIVE CASE-CONTROL STUDY. UNLABELLED: CONTEXT * HIGH ALTITUDE (HA) IS A PSYCHOPHYSIOLOGICAL STRESSOR FOR NATIVES OF LOWER ALTITUDES. REDUCING THE MORBIDITY AND OPTIMIZING THE PERFORMANCE OF INDIVIDUALS DEPLOYED IN AN HA REGION HAS BEEN ATTEMPTED AND REPORTED WITH VARIED RESULTS. OBJECTIVE * THE PRESENT STUDY INTENDED TO EXPLORE THE EFFECTS OF COMPREHENSIVE YOGIC PRACTICES ON THE HEALTH AND PERFORMANCE OF INDIAN SOLDIERS DEPLOYED AT HAS. DESIGN * THE RESEARCH TEAM DESIGNED A PROSPECTIVE, RANDOMIZED, CASE-CONTROL STUDY. SETTING: THE STUDY WAS DONE AT KARU, LEH, INDIA, AT AN ALTITUDE OF 3445 M. PARTICIPANTS * FULLY ACCLIMATIZED SOLDIERS IN THE INDIAN ARMY WERE RANDOMLY SELECTED FROM THOSE POSTED TO HA REGIONS (IE, ALTITUDES >3000 M). INTERVENTION * THE SOLDIERS WERE DIVIDED INTO 2 GROUPS OF EQUAL SIZE. THE FIRST GROUP, THE CONTROL GROUP, CARRIED OUT THE ROUTINE ACTIVITIES FOR PHYSICAL TRAINING IN THE INDIAN ARMY. THE SECOND GROUP, THE INTERVENTION GROUP PRACTICED A COMPREHENSIVE YOGA PACKAGE, INCLUDING PHYSICAL ASANAS, PRANAYAMA, AND MEDITATION, AND DID NOT PERFORM THE PHYSICAL TRAINING THAT THE FIRST GROUP DID. BOTH GROUPS WERE MONITORED DURING THEIR ACTIVITIES. OUTCOME MEASURES * A WIDE AND COMPREHENSIVE RANGE OF ANTHROPOMETRICAL, PHYSIOLOGICAL, BIOCHEMICAL, AND PSYCHOLOGICAL PARAMETERS WERE MEASURED: (1) HEIGHT AND WEIGHT; (2) BODY FAT PERCENTAGE (BFP); (3) HEART RATE (HR); (4) RESPIRATORY RATE (RR); (5) SYSTOLIC AND DIASTOLIC BLOOD PRESSURE (DPB); (6) PERIPHERAL SATURATION OF OXYGEN; (7) END TIDAL CO2 (ETCO2); (8) CHEST EXPANSION; (9) PULMONARY FUNCTION; (10) PHYSICAL WORK CAPACITY (VO2MAX); (11) HEMATOLOGICAL VARIABLES; (12) LIPID PROFILE; (13) SERUM UREA; (14) CREATININE; (15) LIVER ENZYMES; (16) BLOOD GLUCOSE; AND (17) ANXIETY SCORES. MEASUREMENTS WERE MADE AT BASELINE AND POSTINTERVENTION. RESULTS * TWO-HUNDRED SOLDIERS TOOK PART IN THE STUDY. THE YOGA GROUP SHOWED A SIGNIFICANT IMPROVEMENT IN HEALTH INDICES AND PERFORMANCE AS COMPARED WITH THE CONTROL GROUP. THEY HAD LOWER WEIGHTS, BFPS, RRS, DBPS, AND ANXIETY SCORES. THEY ALSO HAD A SIGNIFICANTLY HIGHER ETCO2, FORCED VITAL CAPACITY, FORCED EXPIRATORY VOLUME IN THE FIRST SECOND (FEV1), AND VO2MAX. ALSO, THE YOGA GROUP SHOWED A SIGNIFICANT REDUCTION IN SERUM CHOLESTEROL, LOW-DENSITY LIPOPROTEIN, TRIGLYCERIDES, AND BLOOD UREA AS COMPARED WITH THEIR PREYOGA LEVELS AND WITH THE EXERCISE GROUP. CONCLUSIONS * PRACTICE OF YOGA FACILITATES IMPROVEMENTS IN HEALTH AND PERFORMANCE AT HAS AND IS SUPERIOR TO ROUTINE TRAINING WITH PHYSICAL EXERCISES. COMPREHENSIVE YOGIC PRACTICES ARE AN EFFECTIVE MODALITY FOR IMPROVING HEALTH AND PERFORMANCE AT HAS.	2016	

3  438  34 CARDIOVASCULAR AND RESPIRATORY EFFECT OF YOGIC SLOW BREATHING IN THE YOGA BEGINNER: WHAT IS THE BEST APPROACH? SLOW BREATHING INCREASES CARDIAC-VAGAL BAROREFLEX SENSITIVITY (BRS), IMPROVES OXYGEN SATURATION, LOWERS BLOOD PRESSURE, AND REDUCES ANXIETY. WITHIN THE YOGA TRADITION SLOW BREATHING IS OFTEN PAIRED WITH A CONTRACTION OF THE GLOTTIS MUSCLES. THIS RESISTANCE BREATH "UJJAYI" IS PERFORMED AT VARIOUS RATES AND RATIOS OF INSPIRATION/EXPIRATION. TO TEST WHETHER UJJAYI HAD ADDITIONAL POSITIVE EFFECTS TO SLOW BREATHING, WE COMPARED BRS AND VENTILATORY CONTROL UNDER DIFFERENT BREATHING PATTERNS (EQUAL/UNEQUAL INSPIRATION/EXPIRATION AT 6 BREATH/MIN, WITH/WITHOUT UJJAYI), IN 17 YOGA-NAIVE YOUNG HEALTHY PARTICIPANTS. BRS INCREASED WITH SLOW BREATHING TECHNIQUES WITH OR WITHOUT EXPIRATORY UJJAYI (P < 0.05 OR HIGHER) EXCEPT WITH INSPIRATORY + EXPIRATORY UJJAYI. THE MAXIMAL INCREASE IN BRS AND DECREASE IN BLOOD PRESSURE WERE FOUND IN SLOW BREATHING WITH EQUAL INSPIRATION AND EXPIRATION. THIS CORRESPONDED WITH A SIGNIFICANT IMPROVEMENT IN OXYGEN SATURATION WITHOUT INCREASE IN HEART RATE AND VENTILATION. UJJAYI SHOWED SIMILAR INCREASE IN OXYGEN SATURATION BUT SLIGHTLY LESSER IMPROVEMENT IN BAROREFLEX SENSITIVITY WITH NO CHANGE IN BLOOD PRESSURE. THE SLOW BREATHING WITH EQUAL INSPIRATION AND EXPIRATION SEEMS THE BEST TECHNIQUE FOR IMPROVING BAROREFLEX SENSITIVITY IN YOGA-NAIVE SUBJECTS. THE EFFECTS OF UJJAYI SEEMS DEPENDENT ON INCREASED INTRATHORACIC PRESSURE THAT REQUIRES GREATER EFFORT THAN NORMAL SLOW BREATHING.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
4  324  19 ANTHROPOMETRIC, BIOCHEMICAL AND CLINICAL PARAMETERS IN CLIMACTERIC YOGA PRACTITIONERS. OBJECTIVE: THIS STUDY AIMED TO EVALUATE ANTHROPOMETRIC, BIOCHEMICAL AND CLINICAL PARAMETERS IN CLIMACTERIC YOGA PRACTITIONERS. METHODS: THIS STUDY INVESTIGATED 108 CLIMACTERIC WOMEN. WE RECRUITED 28 WOMEN BETWEEN 40 AND 65 YEARS OLD WHO STARTED YOGA PRACTICES IN PREMENOPAUSE AND HAD ALREADY PRACTICED FOR AT LEAST 5 YEARS. AS CONTROLS, WE SELECTED 30 PHYSICAL ACTIVITY (PA) PRACTITIONERS WHO HAD PRACTICED FOR AT LEAST 5 YEARS AND 50 SEDENTARY WOMEN IN THE SAME AGE RANGE. WE CONDUCED ANTHROPOMETRIC, BIOCHEMICAL AND BLOOD PRESSURE MEASUREMENTS. RESULTS: THE YOGA GROUP HAD SIGNIFICANTLY LOWER FASTING BLOOD GLUCOSE THAN THE PA PRACTITIONERS AND SEDENTARY WOMEN. YOGA PRACTITIONERS ALSO HAD LOWER WEIGHT, BODY MASS INDEX, WAIST CIRCUMFERENCE, BODY FAT PERCENTAGE AND WAIST-TO-HEIGHT RATIO; HIGHER LEVELS OF HIGH-DENSITY LIPOPROTEIN CHOLESTEROL; LOWER LEVELS OF TRIGLYCERIDES, INSULIN, HOMEOSTASIS MODEL ASSESSMENT OF INSULIN RESISTANCE, URIC ACID, APOLIPOPROTEIN B AND HIGH-SENSITIVITY C-REACTIVE PROTEIN; AND LOWER FREQUENCY OF METABOLIC SYNDROME, LIPID ACCUMULATION PRODUCT, VISCERAL ADIPOSITY INDEX AND SYSTOLIC BLOOD PRESSURE THAN THE SEDENTARY WOMEN. CONCLUSION: YOGA PRACTITIONERS HAD LOWER GLUCOSE SERUM CONCENTRATIONS THAN THE PA PRACTITIONERS AND SEDENTARY WOMEN. OVERALL, THE YOGA GROUP ALSO HAD BETTER ANTHROPOMETRIC, BIOCHEMICAL AND CLINICAL VARIABLES THAN THE OTHER GROUPS. ALTHOUGH FURTHER INVESTIGATION IS REQUIRED, YOGA PRACTICE IN PREMENOPAUSE SEEMS TO BE BENEFICIAL FOR WOMEN WHEN THEY REACH MENOPAUSE.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
5 2386  32 YOGA AIDS BLOOD PRESSURE RECOVERY AFTER EXPOSURE OF FOREHEAD TO COLD: A PILOT STUDY. CONTEXT: HYPOTENSION THAT OCCURS AFTER A SINGLE BOUT OF AEROBIC EXERCISE ALSO ATTENUATES THE VASCULAR RESPONSE TO DISCRETE STRESSORS, AN EFFECT THAT CAN LAST FOR HOURS. IT IS UNKNOWN WHETHER THE HYPOTENSIVE BENEFITS OF TRADITIONAL EXERCISE EXTEND TO ALTERNATIVE FORMS OF MINDFUL EXERCISE, SUCH AS YOGA, TO CONFER TRANSIENT PROTECTION AGAINST NEUROVASCULAR CHALLENGES THAT INCREASE BLOOD PRESSURE (BP). OBJECTIVES: THE STUDY INTENDED TO EXAMINE THE EFFECTS OF ACUTE EXERCISE ON NEUROVASCULAR RESPONSES TO EXPOSURE OF THE FOREHEAD OF FEMALE YOGA PRACTITIONERS TO VASOCONSTRICTIVE COLD (IE, TO COLD PRESSOR STRESS). DESIGN: THE RESEARCH TEAM DESIGNED A STUDY WITH 3 CONDITIONS (IE, WITH PARTICIPANTS' PARTICIPATION IN 3 ACTIVITIES ON SEPARATE DAYS IN A REPEATED-MEASURES DESIGN). PARTICIPANTS WERE RANDOMLY ASSIGNED TO PERFORM THE ACTIVITIES IN 1 OF 3 ORDERS ACROSS SUCCESSIVE VISITS. PARTICIPANTS: PARTICIPANTS WERE 9 FEMALES, 20 TO 33 Y OLD, WHO HAD REGULARLY PRACTICED HATHA YOGA FROM 6 MO TO 12 Y BEFORE THE START OF THE STUDY. ALL PARTICIPANTS WERE NORMOTENSIVE AT ENTRY TO THE STUDY AND HAD NORMAL BODY WEIGHTS FOR THEIR HEIGHTS. INTERVENTIONS: ALL PARTICIPANTS PERFORMED 3 ACTIVITIES: (1) SELF-DIRECTED YOGA PRACTICE, THE INTERVENTION; (2) CYCLING EXERCISE AT A SELF-SELECTED INTENSITY, A POSITIVE CONTROL; AND (3) QUIET REST, A NEGATIVE CONTROL. OUTCOME MEASURES: POSTINTERVENTION, PARTICIPANTS' FOREHEADS WERE EXPOSED TO COLD. THEIR SYSTOLIC BLOOD PRESSURES (SBPS), DIASTOLIC BLOOD PRESSURES (DBPS), PULSE RATES, AND FOREARM OXYGENATION WERE ASSESSED USING NEAR-INFRARED SPECTROSCOPY. RESULTS: PARTICIPANTS' SBPS AND DBPS INCREASED DURING COLD PRESSOR STRESS UNDER ALL CONDITIONS, CONCURRENT WITH DECREASED FOREARM OXYGENATION. DURING RECOVERY FROM THE COLD, PARTICIPANTS' BPS DECLINED TO NEAR PRECOLD PRESSOR BASELINE LEVELS AFTER YOGA AND CYCLING BUT REMAINED ELEVATED AFTER QUIET REST. CONCLUSIONS: THE ENHANCED RECOVERY OF BP FROM COLD APPLIED TO THE FOREHEAD AFTER YOGA PRACTICE OR CYCLING EXERCISE SUGGESTS THAT BOTH TYPES OF EXERCISE PROMOTE A HYPOTENSIVE RESPONSE, WHICH COULD INDICATE LOWERED CARDIOVASCULAR RISK.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
6 1305  26 HATHA YOGA PRACTICES: ENERGY EXPENDITURE, RESPIRATORY CHANGES AND INTENSITY OF EXERCISE. THE AIM OF THIS STUDY WAS TO CRITICALLY OBSERVE THE ENERGY EXPENDITURE, EXERCISE INTENSITY AND RESPIRATORY CHANGES DURING A FULL YOGA PRACTICE SESSION. OXYGEN CONSUMPTION ([FORMULA: SEE TEXT]), CARBON DIOXIDE OUTPUT ([FORMULA: SEE TEXT]), PULMONARY VENTILATION ([FORMULA: SEE TEXT]E), RESPIRATORY RATE (FR) AND TIDAL VOLUME (VT), WERE MEASURED IN 16 PHYSICAL POSTURE (ASANAS), FIVE YOGA BREATHING MANEUVERS (BM) AND TWO TYPES OF MEDITATION. TWENTY MALE (AGE 27.3 +/- 3.5 YEARS, HEIGHT 166.6 +/- 5.4 CM AND BODY WEIGHT 58.8 +/- 9.6 KG) YOGA INSTRUCTORS WERE STUDIED. THEIR MAXIMAL OXYGEN CONSUMPTION ([FORMULA: SEE TEXT]) WAS RECORDED. THE EXERCISE INTENSITY IN ASANAS WAS EXPRESSED IN PERCENTAGE [FORMULA: SEE TEXT] . IN ASANAS, EXERCISE INTENSITY VARIED FROM 9.9 TO 26.5% OF [FORMULA: SEE TEXT] . HIGHEST ENERGY COST WAS 3.02 KCAL MIN(-1). IN BM HIGHEST [FORMULA: SEE TEXT]E WAS 53.7 +/- 15.5 L MIN(-1). VT WAS 0.97 +/- 0.59, 1.41 +/- 1.27 AND 1.28 +/- L/BREATH WITH CORRESPONDING FR OF 14.0 +/- 5.3, 10.0 +/- 6.35, 10.0 +/- 5.8 BREATHS/MIN. AVERAGE ENERGY EXPENDITURE IN ASANAS, BM AND MEDITATION WERE 2.29, 1.91 AND 1.37 KCAL MIN(-1), RESPECTIVELY. METABOLIC RATE WAS GENERALLY IN THE RANGE OF 1-2 METABOLIC EQUIVALENTS (MET) EXCEPT IN THREE ASANAS WHERE IT WAS >2 MET. [FORMULA: SEE TEXT] WAS 0.27 +/- 0.05 AND 0.24 +/- 0.04 L MIN(-1) IN MEDITATION AND SHAVASANA, RESPECTIVELY. ALTHOUGH YOGIC PRACTICES ARE LOW INTENSITY EXERCISES WITHIN LACTATE THRESHOLD, PHYSICAL PERFORMANCE IMPROVEMENT IS POSSIBLE OWING TO BOTH BETTER ECONOMY OF BREATHING BY BM AND ALSO BY IMPROVEMENT IN CARDIOVASCULAR RESERVE. OTHER FACTORS SUCH AS PSYCHO-PHYSIOLOGICAL AND BETTER RELAXATION MAY CONTRIBUTE TO IT.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
7  758  29 EFFECT OF SLOW BREATHING ON AUTONOMIC TONE & BAROREFLEX SENSITIVITY IN YOGA PRACTITIONERS. BACKGROUND & OBJECTIVES: SLOW BREATHING INCREASES PARASYMPATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY (BRS) IN HEALTHY INDIVIDUALS, ALSO SIMILARLY OBSERVED IN YOGA PRACTITIONERS. PRANAYAMA WHICH IS AN IMPORTANT COMPONENT OF YOGA WHEN PRACTICED AT A SLOW PACE WAS AT A RESPIRATORY FREQUENCY OF AROUND 0.1 HZ (6 BREATHS/MIN). THEREFORE, IT WAS HYPOTHESIZED THAT YOGA PRACTITIONERS MIGHT HAVE ADAPTED TO SLOW BREATHING. THIS STUDY WAS AIMED TO DECIPHER THE ROLE OF YOGA ON CARDIOVASCULAR VARIABILITY DURING SLOW BREATHING (0.1 HZ) IN YOGA PRACTITIONERS. METHODS: A CROSS-SECTIONAL STUDY WAS UNDERTAKEN IN NAIVE-TO-YOGA INDIVIDUALS (N=40) AND YOGA PRACTITIONERS (N=40) WITH AN AVERAGE AGE OF 31.08 +/- 7.31 AND 29.93 +/- 7.57 YR, RESPECTIVELY. THE ANALYSIS OF HEART RATE VARIABILITY, BLOOD PRESSURE VARIABILITY (BPV) AND BRS DURING SPONTANEOUS AND SLOW BREATHING WAS COMPARED BETWEEN THE TWO GROUPS. RESULTS: DURING SLOW BREATHING, THE HEART RATE (P<0.01) WAS LOWER, RESPIRATORY RATE INTERVAL (P<0.05) AND PNN50 PER CENT (P=0.01) WERE HIGHER, MEAN SYSTOLIC BP (SBP) (P<0.05) AND SDSD (STANDARD DEVIATION OF SUCCESSIVE BEAT TO BEAT SYSTOLIC BLOOD PRESSURE DIFFERENCES) (P<0.01) OF SBP VARIABILITY WERE LOWER WITH SEQUENCE BRS (P<0.001) AND ALPHA LOW FREQUENCY (P<0.01) AND ALPHA HIGH FREQUENCY (P<0.001) OF SPECTRAL BRS WERE HIGHER IN YOGA PRACTITIONERS. INTERPRETATION & CONCLUSIONS: THE PRESENT STUDY INDICATED HIGHER PARASYMPATHETIC ACTIVITY AND BRS WITH LOWER SBP VARIABILITY AT REST AND DURING SLOW BREATHING IN YOGA PRACTITIONERS COMPARED TO NAIVE GROUP. FINDINGS INDICATE THAT THE SHORT-TERM PRACTICE OF SLOW BREATHING COMPLEMENTS THE AUGMENTED PARASYMPATHETIC ACTIVITY AND BRS IN THE YOGA GROUP.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
8 1374  26 IMPACT OF AN INTEGRATED YOGA THERAPY PROTOCOL ON INSULIN RESISTANCE AND GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. OBJECTIVE: DIABETES MELLITUS (DM), CHARACTERIZED BY CHRONIC HYPERGLYCEMIA, IS ATTRIBUTED TO RELATIVE INSULIN DEFICIENCY OR RESISTANCE, OR BOTH. STUDIES HAVE SHOWN THAT YOGA CAN MODULATE PARAMETERS OF INSULIN RESISTANCE. THE PRESENT STUDY EXPLORED THE POSSIBLE BENEFICIAL EFFECTS OF INTEGRATED YOGA THERAPY WITH REFERENCE TO GLYCEMIC CONTROL AND INSULIN RESISTANCE (IR) IN INDIVIDUALS WITH DIABETES MAINTAINED ON STANDARD ORAL MEDICAL CARE WITH YOGA THERAPY, COMPARED TO THOSE ON STANDARD ORAL MEDICAL CARE ALONE. METHODS: IN THIS STUDY, THE SUBJECTS ON YOGA INTERVENTION COMPRISED 35 TYPE 2 DIABETICS, AND AN EQUAL NUMBER OF VOLUNTEERS CONSTITUTED THE CONTROL GROUP. SUBJECTS RANGED IN AGE FROM 30 TO 70 YEARS, WITH HEMOGLOBIN A1C (HBA1C) TEST MORE THAN 7%, AND WERE MAINTAINED ON DIABETIC DIET AND ORAL HYPOGLYCEMIC AGENTS. BLOOD SAMPLES WERE DRAWN PRIOR TO AND AFTER 120 DAYS OF INTEGRATED YOGA THERAPY INTERVENTION. FASTING BLOOD GLUCOSE (FBG), POST-PRANDIAL BLOOD GLUCOSE (PPBG), HBA1C, INSULIN, AND LIPID PROFILE WERE ASSESSED IN BOTH THE INTERVENTION AND CONTROL GROUPS. RESULTS: THE INTERVENTION GROUP REVEALED SIGNIFICANT IMPROVEMENTS IN BODY MASS INDEX (BMI) (0.7 KG/M(2) MEDIAN DECREASE; P=0.001), FBG (20 MG/DL MEDIAN DECREASE; P<0.001), PPBG (33 MG/DL MEDIAN DECREASE; P<0.001), HBA1C (0.4% MEDIAN DECREASE; P<0.001), HOMEOSTATIC MODEL ASSESSMENT FOR INSULIN RESISTANCE (HOMA-IR) (1.2 MEDIAN DECREASE; P<0.001), CHOLESTEROL (13 MG/DL MEDIAN DECREASE, P=0.006), TRIACYLGLYCEROL (22 MG/DL MEDIAN DECREASE; P=0.027), LOW-DENSITY LIPOPROTEIN (6 MG/DL MEDIAN DECREASE; P=0.004), AND VERY-LOW-DENSITY LIPOPROTEIN LEVELS (4 MG/DL MEDIAN DECREASE; P=0.032). INCREASES IN HIGH-DENSITY LIPOPROTEIN AFTER 120 DAYS WERE NOT SIGNIFICANT (6 MG/DL MEDIAN INCREASE; P=0.15). HOWEVER, WHEN COMPARED TO CHANGES OBSERVED IN PATIENTS IN THE CONTROL GROUP, ALL THESE IMPROVEMENTS PROVED TO BE SIGNIFICANT. CONCLUSION: ADMINISTRATION OF INTEGRATED YOGA THERAPY TO INDIVIDUALS WITH DIABETES LEADS TO A SIGNIFICANT IMPROVEMENT IN GLYCEMIC CONTROL, INSULIN RESISTANCE, AND KEY BIOCHEMICAL PARAMETERS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
9   90  24 A MODIFIED YOGA-BASED EXERCISE PROGRAM IN HEMODIALYSIS PATIENTS: A RANDOMIZED CONTROLLED STUDY. AIM: TO EVALUATE THE EFFECTS OF A YOGA-BASED EXERCISE PROGRAM ON PAIN, FATIGUE, SLEEP DISTURBANCE, AND BIOCHEMICAL MARKERS IN HEMODIALYSIS PATIENTS. MATERIALS AND METHODS: IN 2004 A RANDOMIZED CONTROLLED TRIAL WAS CARRIED OUT IN THE OUTPATIENT HEMODIALYSIS UNIT OF THE NEPHROLOGY DEPARTMENT, ULUDAG UNIVERSITY FACULTY OF MEDICINE. CLINICALLY STABLE HEMODIALYSIS PATIENTS (N=37) WERE INCLUDED AND FOLLOWED IN TWO GROUPS: THE MODIFIED YOGA-BASED EXERCISE GROUP (N=19) AND THE CONTROL GROUP (N=18). YOGA-BASED EXERCISES WERE DONE IN GROUPS FOR 30 MIN/DAY TWICE A WEEK FOR 3 MONTHS. ALL OF THE PATIENTS IN THE YOGA AND CONTROL GROUPS WERE GIVEN AN ACTIVE RANGE OF MOTION EXERCISES TO DO FOR 10 MIN AT HOME. THE MAIN OUTCOME MEASURES WERE PAIN INTENSITY (MEASURED BY THE VISUAL ANALOGUE SCALE, VAS), FATIGUE (VAS), SLEEP DISTURBANCE (VAS), AND GRIP STRENGTH (MMHG); BIOCHEMICAL VARIABLES-- UREA, CREATININE, CALCIUM, ALKALINE PHOSPHATASE, PHOSPHORUS, CHOLESTEROL, HDL-CHOLESTEROL, TRIGLYCERIDE, ERYTHROCYTE, HEMATOCRIT--WERE EVALUATED. RESULTS: AFTER A 12-WEEK INTERVENTION, SIGNIFICANT IMPROVEMENTS WERE SEEN IN THE VARIABLES: PAIN -37%, FATIGUE -55%, SLEEP DISTURBANCE -25%, GRIP STRENGTH +15%, UREA -29%, CREATININE -14%, ALKALINE PHOSPHATASE -15%, CHOLESTEROL -15%, ERYTHROCYTE +11%, AND HEMATOCRIT COUNT +13%; NO SIDE-EFFECTS WERE SEEN. IMPROVEMENT OF THE VARIABLES IN THE YOGA-BASED EXERCISE PROGRAM WAS FOUND TO BE SUPERIOR TO THAT IN THE CONTROL GROUP FOR ALL THE VARIABLES EXCEPT CALCIUM, PHOSPHORUS, HDL-CHOLESTEROL AND TRIGLYCERIDE LEVELS. CONCLUSION: A SIMPLIFIED YOGA-BASED REHABILITATION PROGRAM IS A COMPLEMENTARY, SAFE AND EFFECTIVE CLINICAL TREATMENT MODALITY IN PATIENTS WITH END-STAGE RENAL DISEASE.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
10  435  27 CARDIOPULMONARY AND METABOLIC EFFECTS OF YOGA IN HEALTHY VOLUNTEERS. BACKGROUND: YOGA THE SPIRITUAL UNION OF MIND WITH THE DIVINE INTELLIGENCE OF THE UNIVERSE AIMS TO LIBERATE A HUMAN BEING FROM CONFLICTS OF BODY-MIND DUALITY. BENEFICIAL CARDIOVASCULAR AND PULMONARY EFFECTS OF YOGA ARE IN PAR WITH AEROBIC EXERCISE, EVEN AMOUNTING TO REPLACE THE EXERCISE MODEL. WE CONDUCTED AN INTERVENTIONAL STUDY IN HEALTHY VOLUNTEERS, TO ANALYZE THE IMPACT OF SHORT-TERM YOGA TRAINING ON CARDIOVASCULAR, PULMONARY, AUTONOMIC FUNCTION TESTS, LIPID PROFILE, AND THYROID FUNCTION TESTS. MATERIALS AND METHODS: A SAMPLE OF FIFTY NEW RECRUITS ATTENDING THE DISTRICT YOGA CENTER WAS SUBJECT TO 75 MIN YOGA PRACTICE A DAY FOR 41 DAYS. BASAL VALUES OF CARDIOVASCULAR, PULMONARY, AUTONOMIC FUNCTION TESTS, LIPID PROFILE, AND THYROID FUNCTION TESTS WERE RECORDED BEFORE YOGA TRAINING AND WERE REASSESSED FOR POSTYOGA CHANGES AFTER 41 DAYS. RESULTS: AFTER YOGA PRACTICE THERE WAS A SIGNIFICANT REDUCTION IN THE RESTING HEART RATE, SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE, AND MEAN BLOOD PRESSURE OF THE PARTICIPANTS. EFFECTS ON AUTONOMIC FUNCTION TESTS WERE VARIABLE AND INCONCLUSIVE. THERE WAS A SIGNIFICANT INCREASE IN FORCED VITAL CAPACITY, FORCED EXPIRATORY VOLUME IN 1 S, AND PEAK EXPIRATORY FLOW RATE AFTER YOGA. A SIGNIFICANT REDUCTION IN BODY MASS INDEX WAS OBSERVED. EFFECTS ON METABOLIC PARAMETERS WERE PROMISING WITH A SIGNIFICANT REDUCTION IN FASTING BLOOD SUGAR LEVEL, SERUM TOTAL CHOLESTEROL, SERUM TRIGLYCERIDES SERUM LOW-DENSITY LIPOPROTEIN LEVELS, AND SIGNIFICANT INCREASE IN HIGH-DENSITY LIPOPROTEIN. THERE WAS NO SIGNIFICANT CHANGE IN THYROID FUNCTION TESTS AFTER YOGA. CONCLUSION: SHORT-TERM YOGA PRACTICE HAS NO EFFECT ON THYROID FUNCTIONS. YOGA PRACTICE WAS FOUND BENEFICIAL IN MAINTAINING PHYSIOLOGICAL MILIEU PERTAINING TO CARDIOVASCULAR AND OTHER METABOLIC PARAMETERS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
11  985  31 EFFECTS OF HATHA YOGA AND OMKAR MEDITATION ON CARDIORESPIRATORY PERFORMANCE, PSYCHOLOGIC PROFILE, AND MELATONIN SECRETION. OBJECTIVES: TO EVALUATE EFFECTS OF HATHA YOGA AND OMKAR MEDITATION ON CARDIORESPIRATORY PERFORMANCE, PSYCHOLOGIC PROFILE, AND MELATONIN SECRETION. SUBJECTS AND METHODS: THIRTY HEALTHY MEN IN THE AGE GROUP OF 25-35 YEARS VOLUNTEERED FOR THE STUDY. THEY WERE RANDOMLY DIVIDED IN TWO GROUPS OF 15 EACH. GROUP 1 SUBJECTS SERVED AS CONTROLS AND PERFORMED BODY FLEXIBILITY EXERCISES FOR 40 MINUTES AND SLOW RUNNING FOR 20 MINUTES DURING MORNING HOURS AND PLAYED GAMES FOR 60 MINUTES DURING EVENING HOURS DAILY FOR 3 MONTHS. GROUP 2 SUBJECTS PRACTICED SELECTED YOGIC ASANAS (POSTURES) FOR 45 MINUTES AND PRANAYAMA FOR 15 MINUTES DURING THE MORNING, WHEREAS DURING THE EVENING HOURS THESE SUBJECTS PERFORMED PREPARATORY YOGIC POSTURES FOR 15 MINUTES, PRANAYAMA FOR 15 MINUTES, AND MEDITATION FOR 30 MINUTES DAILY, FOR 3 MONTHS. ORTHOSTATIC TOLERANCE, HEART RATE, BLOOD PRESSURE, RESPIRATORY RATE, DYNAMIC LUNG FUNCTION (SUCH AS FORCED VITAL CAPACITY, FORCED EXPIRATORY VOLUME IN 1 SECOND, FORCED EXPIRATORY VOLUME PERCENTAGE, PEAK EXPIRATORY FLOW RATE, AND MAXIMUM VOLUNTARY VENTILATION), AND PSYCHOLOGIC PROFILE WERE MEASURED BEFORE AND AFTER 3 MONTHS OF YOGIC PRACTICES. SERIAL BLOOD SAMPLES WERE DRAWN AT VARIOUS TIME INTERVALS TO STUDY EFFECTS OF THESE YOGIC PRACTICES AND OMKAR MEDITATION ON MELATONIN LEVELS. RESULTS: YOGIC PRACTICES FOR 3 MONTHS RESULTED IN AN IMPROVEMENT IN CARDIORESPIRATORY PERFORMANCE AND PSYCHOLOGIC PROFILE. THE PLASMA MELATONIN ALSO SHOWED AN INCREASE AFTER THREE MONTHS OF YOGIC PRACTICES. THE SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE, MEAN ARTERIAL PRESSURE, AND ORTHOSTATIC TOLERANCE DID NOT SHOW ANY SIGNIFICANT CORRELATION WITH PLASMA MELATONIN. HOWEVER, THE MAXIMUM NIGHT TIME MELATONIN LEVELS IN YOGA GROUP SHOWED A SIGNIFICANT CORRELATION (R = 0.71, P < 0.05) WITH WELL-BEING SCORE. CONCLUSION: THESE OBSERVATIONS SUGGEST THAT YOGIC PRACTICES CAN BE USED AS PSYCHOPHYSIOLOGIC STIMULI TO INCREASE ENDOGENOUS SECRETION OF MELATONIN, WHICH, IN TURN, MIGHT BE RESPONSIBLE FOR IMPROVED SENSE OF WELL-BEING.	2004	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
12  865  28 EFFECT OF YOGA PRACTICES ON PULMONARY FUNCTION TESTS INCLUDING TRANSFER FACTOR OF LUNG FOR CARBON MONOXIDE (TLCO) IN ASTHMA PATIENTS. PRANA IS THE ENERGY, WHEN THE SELF-ENERGIZING FORCE EMBRACES THE BODY WITH EXTENSION AND EXPANSION AND CONTROL, IT IS PRANAYAMA. IT MAY AFFECT THE MILIEU AT THE BRONCHIOLES AND THE ALVEOLI PARTICULARLY AT THE ALVEOLO-CAPILLARY MEMBRANE TO FACILITATE DIFFUSION AND TRANSPORT OF GASES. IT MAY ALSO INCREASE OXYGENATION AT TISSUE LEVEL. AIM OF OUR STUDY IS TO COMPARE PULMONARY FUNCTIONS AND DIFFUSION CAPACITY IN PATIENTS OF BRONCHIAL ASTHMA BEFORE AND AFTER YOGIC INTERVENTION OF 2 MONTHS. SIXTY STABLE ASTHMATIC-PATIENTS WERE RANDOMIZED INTO TWO GROUPS I.E GROUP 1 (YOGA TRAINING GROUP) AND GROUP 2 (CONTROL GROUP). EACH GROUP INCLUDED THIRTY PATIENTS. LUNG FUNCTIONS WERE RECORDED ON ALL PATIENTS AT BASELINE, AND THEN AFTER TWO MONTHS. GROUP 1 SUBJECTS SHOWED A STATISTICALLY SIGNIFICANT IMPROVEMENT (P<0.001) IN TRANSFER FACTOR OF THE LUNG FOR CARBON MONOXIDE (TLCO), FORCED VITAL CAPACITY (FVC), FORCED EXPIRATORY VOLUME IN 1ST SEC (FEV1), PEAK EXPIRATORY FLOW RATE (PEFR), MAXIMUM VOLUNTARY VENTILATION (MVV) AND SLOW VITAL CAPACITY (SVC) AFTER YOGA PRACTICE. QUALITY OF LIFE ALSO INCREASED SIGNIFICANTLY. IT WAS CONCLUDED THAT PRANAYAMA & YOGA BREATHING AND STRETCHING POSTURES ARE USED TO INCREASE RESPIRATORY STAMINA, RELAX THE CHEST MUSCLES, EXPAND THE LUNGS, RAISE ENERGY LEVELS, AND CALM THE BODY.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
13  674  21 EFFECT OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE IN OVERWEIGHT AND OBESE SUBJECTS. OBJECTIVE: TO STUDY THE EFFECT OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN OVERWEIGHT AND OBESE PERSONS. DESIGN AND SETTING: NONRANDOMIZED, SINGLE-ARM INTERVENTIONAL STUDY CONDUCTED FROM AUGUST 2012 TO MARCH 2015 AT INTEGRAL HEALTH CLINIC, DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA. PARTICIPANTS: OVERWEIGHT (BODY-MASS INDEX [BMI], 23-24.9 KG/M(2)) AND OBESE (BMI, >/=25 KG/M(2)) PERSONS (N = 279) AGED 20-60 YEARS. INTERVENTION: PRETESTED YOGA-BASED LIFESTYLE INTERVENTION, INCLUDING ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), RELAXATION TECHNIQUES, LECTURES, GROUP SUPPORT, NUTRITION AWARENESS PROGRAM, AND INDIVIDUALIZED ADVICE. OUTCOME MEASURES: PRIMARY OUTCOME MEASURE WAS HRQOL, MEASURED BY USING SHORT VERSION OF WORLD HEALTH ORGANIZATION QUALITY OF LIFE (WHOQOL-BREF) QUESTIONNAIRE. SECONDARY OUTCOME MEASURES WERE ANTHROPOMETRIC VARIABLES, SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, PULSE RATE, LIPID PROFILE, AND FASTING GLUCOSE. A SUBGROUP ANALYSIS ACCORDING TO SEX WAS ALSO PERFORMED. RESULTS: THE OVERALL QUALITY OF LIFE AND HEALTH IMPROVED AFTER SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION IN OVERWEIGHT AND OBESE PERSONS. PHYSICAL, PSYCHOLOGICAL AND ENVIRONMENTAL DOMAIN SCORES SIGNIFICANTLY INCREASED FROM BASELINE TO DAY 10, AND EFFICACY WAS NOTED IN BOTH MALE AND FEMALE SUBGROUPS. AFTER 10 DAYS OF INTERVENTION, THE FOLLOWING ALSO DECREASED SIGNIFICANTLY: BODY WEIGHT, BMI, TOTAL BODY FAT, WAIST AND HIP CIRCUMFERENCE, WAIST-TO-HIP RATIO, SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, TOTAL CHOLESTEROL, LOW-DENSITY LIPOPROTEIN, TRIGLYCERIDES, AND FASTING GLUCOSE. CONCLUSION: A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION HAD A POSITIVE EFFECT ON HRQOL IN OVERWEIGHT AND OBESE PERSONS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
14  370  33 AUTONOMIC TONE AND BAROREFLEX SENSITIVITY DURING 70 DEGREES HEAD-UP TILT IN YOGA PRACTITIONERS. INTRODUCTION: THE INTERVENTION OF YOGA WAS SHOWN TO IMPROVE THE AUTONOMIC CONDITIONING IN HUMANS EVIDENT FROM THE ENHANCEMENT OF PARASYMPATHETIC ACTIVITY AND BAROREFLEX SENSITIVITY (BRS). FROM THE DOCUMENTED HEALTH BENEFITS OF YOGA, WE HYPOTHESIZED THAT THE EXPERIENCE OF YOGA MAY RESULT IN ADAPTATION TO THE ORTHOSTATIC STRESS DUE TO ENHANCED BRS. AIM: TO DECIPHER THE EFFECTS OF YOGA IN THE MODULATION OF AUTONOMIC FUNCTION DURING ORTHOSTATIC CHALLENGE. MATERIALS AND METHODS: THIS WAS A COMPARATIVE STUDY DESIGN CONDUCTED IN AUTONOMIC FUNCTION TEST LAB, OF THE DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA. HEART RATE VARIABILITY (HRV), BLOOD PRESSURE VARIABILITY, AND BRS WERE ANALYZED ON FORTY NAIVE TO YOGA (NY) SUBJECTS AND FORTY YOGA PRACTITIONERS WITH AN AVERAGE AGE OF 31.08 +/- 7.31 YEARS AND 29.93 +/- 7.57 YEARS, RESPECTIVELY. ALL PARTICIPANTS WERE HEALTHY. SEVENTY DEGREES HEAD UP TILT (HUT) WAS USED AS AN INTERVENTION TO EVALUATE THE CARDIOVASCULAR VARIABILITY DURING ORTHOSTATIC CHALLENGE. RESULTS: DURING HUT, THE R-R INTERVAL (P = 0.042), ROOT MEAN SQUARE OF SUCCESIVE R-R INTERVAL DIFFERENCES (RMSSD) (P = 0.039), STANDARD DEVIATION OF INSTANTANEOUS BEAT-TO-BEAT R-R INTERVAL VARIABILITY (SD1) (P = 0.039) OF HRV, AND SEQUENCE BRS (P = 0.017) AND ALPHA LOW FREQUENCY OF SPECTRAL BRS (P = 0.002) WERE HIGHER IN THE YOGA GROUP. THE DELTA DECREASE IN RRI (P = 0.033) AND BRS (P < 0.01) WAS HIGHER IN THE YOGA GROUP THAN THE NY GROUP. CONCLUSION: THE EFFERENT VAGAL ACTIVITY AND BRS WERE HIGHER IN YOGA PRACTITIONERS. THE DELTA CHANGE (DECREASE) IN PARASYMPATHETIC ACTIVITY AND BRS WAS HIGHER, WITH RELATIVELY STABLE SYSTOLIC BLOOD PRESSURE INDICATING AN ADAPTIVE RESPONSE TO ORTHOSTATIC CHALLENGE BY THE YOGA PRACTITIONERS COMPARED TO THE NY GROUP.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
15 2153  23 THE EFFECTS OF SUDARSHAN KRIYA YOGA ON SOME PHYSIOLOGICAL AND BIOCHEMICAL PARAMETERS IN MILD HYPERTENSIVE PATIENTS. AN OPEN LABEL INTERVENTION STUDY WAS UNDERTAKEN ON 26 MILD HYPERTENSIVES AND 26 APPARENTLY HEALTHY ADULTS (30-60 Y), FOR THE EFFECT OF SUDARSHAN KRIYA YOGA PRACTICE FOR TWO MONTHS AS COMPLEMENTARY THERAPY. IN THE HYPERTENSIVES, THERE WAS A SIGNIFICANT DECREASE IN DIASTOLIC BLOOD PRESSURE (P < 0.01), SERUM UREA (P < 0.01) AND PLASMA MDA (MALONDIALDEHYDE ADDUCTS) AS OXIDATIVE STRESS MARKER (P < 0.05). OTHER PARAMETERS; VIZ.; PLASMA LEVELS OF CHOLESTEROL, TRIGLYCERIDES, GLUCOSE, DID NOT CHANGE SIGNIFICANTLY (P > 0.1). THE PATTERN OF CHANGE IN MOST OF THE STUDY PARAMETERS WAS SUCH THAT VALUES ABOVE NORMAL RANGE WERE LOWERED BUT VALUES WITHIN NORMAL RANGE WERE UNALTERED. THE ACTION OF YOGA ON DIASTOLIC BLOOD PRESSURE, MALONDIALDEHYDE ADDUCTS AND KIDNEY FUNCTION IN HYPERTENSIVES WAS OF COUNTERACTIVE NATURE AND FELT TO BE DISTINCTLY DIFFERENT THAN THE EFFECT OF DRUGS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
16  300  30 AN ASSESSMENT OF A SEQUENCE OF YOGA EXERCISES TO PATIENTS WITH ARTERIAL HYPERTENSION. THIS QUASI-EXPERIMENTAL STUDY DESCRIBES THE EFFECTS OF A YOGA SEQUENCE FOLLOWING HEMODYNAMIC AND BIOCHEMICAL PARAMETERS IN PATIENTS WITH HYPERTENSION. THIRTY-THREE VOLUNTEERS PARTICIPATED IN THE STUDY (CONTROL = 16 AND YOGA = 17) FOR FOUR MONTHS. BLOOD PRESSURE MEASUREMENTS, CARDIAC AND RESPIRATORY RATE WERE COLLECTED MONTHLY, WHILE THE BIOCHEMICAL PROFILE WAS TAKEN AT THE BEGINNING AND END OF THE PROGRAM. TO ANALYZE THE DATA, STUDENT'S T TEST AND REPEATED MEASURES ANALYSES WERE PERFORMED. THE YOGA GROUP SHOWED A SIGNIFICANT REDUCTION OF SYSTOLIC BLOOD PRESSURE, HEART AND RESPIRATORY RATE (P < 0.05). AS FOR THE BIOCHEMICAL PROFILE, THE YOGA GROUP SHOWED CORRELATION COEFFICIENTS BETWEEN INITIAL VALUES AND FINAL RESPONSES GREATER THAN THE CONTROL OF FASTING GLUCOSE, TOTAL CHOLESTEROL, LDL-CHOLESTEROL AND TRIGLYCERIDES. THE ELABORATED SEQUENCE PRACTICE PROMOTED SIGNIFICANT CARDIOVASCULAR AND METABOLIC BENEFITS. THE YOGA EXERCISES PERFORMED IN THE PROPOSED SEQUENCE CONSTITUTE COMPLEMENTARY NON-PHARMACOLOGICAL CONTROL OF BLOOD PRESSURE IN PATIENTS WITH HYPERTENSION.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
17 1898  30 RESTORATIVE YOGA AND METABOLIC RISK FACTORS: THE PRACTICING RESTORATIVE YOGA VS. STRETCHING FOR THE METABOLIC SYNDROME (PRYSMS) RANDOMIZED TRIAL. AIMS: INTENSIVE LIFESTYLE CHANGE PREVENTS TYPE 2 DIABETES BUT IS DIFFICULT TO SUSTAIN. PRELIMINARY EVIDENCE SUGGESTS THAT YOGA MAY IMPROVE METABOLIC FACTORS. WE TESTED A RESTORATIVE YOGA INTERVENTION VS. ACTIVE STRETCHING FOR METABOLIC OUTCOMES. METHODS: IN 2009-2012, WE CONDUCTED A 48-WEEK RANDOMIZED TRIAL COMPARING RESTORATIVE YOGA VS. STRETCHING AMONG UNDERACTIVE ADULTS WITH THE METABOLIC SYNDROME AT THE UNIVERSITIES OF CALIFORNIA, SAN FRANCISCO AND SAN DIEGO. WE PROVIDED LIFESTYLE COUNSELING AND A TAPERING SERIES OF 90-MIN GROUP CLASSES IN THE 24-WEEK INTERVENTION PERIOD AND 24-WEEK MAINTENANCE PERIOD. FASTING AND 2-H GLUCOSE, HBA1C, TRIGLYCERIDES, HDL-CHOLESTEROL, INSULIN, SYSTOLIC BLOOD PRESSURE, VISCERAL FAT, AND QUALITY OF LIFE WERE ASSESSED AT BASELINE, 6- AND 12-MONTHS. RESULTS: 180 PARTICIPANTS WERE RANDOMIZED AND 135 (75%) COMPLETED THE TRIAL. AT 12 MONTHS, FASTING GLUCOSE DECREASED MORE IN THE YOGA GROUP THAN IN THE STRETCHING GROUP (-0.35 MMOL/L VS. -0.03 MMOL/L; P=0.002); THERE WERE NO OTHER SIGNIFICANT DIFFERENCES BETWEEN GROUPS. AT 6 MONTHS FAVORABLE CHANGES WITHIN THE YOGA GROUP INCLUDED REDUCTIONS IN FASTING GLUCOSE, INSULIN, AND HBA1C AND AN INCREASE IN HDL-CHOLESTEROL THAT WERE NOT SUSTAINED AT 1 YEAR EXCEPT CHANGES IN FASTING GLUCOSE. THE STRETCHING GROUP HAD A SIGNIFICANT REDUCTION IN TRIGLYCERIDES AT 6 MONTHS WHICH WAS NOT SUSTAINED AT 1 YEAR BUT HAD IMPROVED QUALITY OF LIFE AT BOTH TIME-POINTS. CONCLUSIONS: RESTORATIVE YOGA WAS MARGINALLY BETTER THAN STRETCHING FOR IMPROVING FASTING GLUCOSE BUT NOT OTHER METABOLIC FACTORS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
18  751  18 EFFECT OF SHORT TERM YOGA PRACTICE ON VENTILATORY FUNCTION TESTS. TWENTYFIVE NORMAL MALE VOLUNTEERS UNDERGOING A TEN WEEKS COURSE IN THE PRACTICE OF YOGA HAVE BEEN STUDIED BY SOME PARAMETERS OF VENTILATORY FUNCTIONS TESTS. THE OBSERVATIONS RECORDED AT THE END OF TEN WEEKS OF THE COURSE HAVE SHOWN IMPROVED VENTILATORY FUNCTIONS IN THE FORM OF LOWERED RESPIRATORY RATE, INCREASED FORCED VITAL CAPACITY, FEV1, MAXIMUM BREATHING CAPACITY AND BREATH HOLDING TIME, WHILE TIDAL VOLUME AND %FEV1, DID NOT REVEAL ANY SIGNIFICANT CHANGE. THUS, A COMBINED PRACTICE OF YOGA SEEMS TO BE BENEFICIAL ON RESPIRATORY EFFICIENCY.	1988	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
19  752  31 EFFECT OF SHORT-TERM AND LONG-TERM BRAHMAKUMARIS RAJA YOGA MEDITATION ON PHYSIOLOGICAL VARIABLES. EFFECT OF SHORT-TERM AND LONG-TERM BRAHMAKUMARIS RAJA YOGA MEDITATION ON PHYSIOLOGICAL VARIABLES LIKE HEART RATE (HR), RESPIRATORY RATE (RR), SYSTOLIC BLOOD PRESSURE (SBP) AND DIASTOLIC BLOOD PRESSURE (DBP) WAS EVALUATED IN 100 SUBJECTS PRACTICING RAJA YOGA MEDITATION. ALL 100 SUBJECTS (33 MEN AND 67 WOMEN) WERE AGED 30 YEARS AND ABOVE (MEAN AGE 52.06 +/- 12.76 YEARS). SHORT-TERM MEDITATORS (STM) (N = 27) PRACTICED RAJA YOGA MEDITATION FOR DURATION OF SIX MONTHS TO FIVE YEARS (MEAN DURATION 3.37 +/- 1.67 YEARS) AND LONG-TERM MEDITATORS (LTM) (N = 73) PRACTICED RAJA YOGA MEDITATION FOR MORE THAN FIVE YEARS (MEAN DURATION 11.19 +/- 5.13 YEARS). THE PARTICIPANTS WERE ASKED TO MEDITATE AND THE PHYSIOLOGICAL VARIABLES (HR, RR, SBP AND DBP) WERE RECORDED TWICE (15 MINUTES AND 30 MINUTES) AFTER BEGINNING OF MEDITATION. ALSO, THE FASTING BLOOD SUGAR WAS ESTIMATED BY GLUCOMETER. THE STUDY SUBJECTS DID NOT DIFFER SIGNIFICANTLY IN AGE AND VARIOUS ANTHROPOMETRIC CHARACTERISTICS SUCH AS BODY WEIGHT, BODY MASS INDEX, WAIST-HIP RATIO AND FASTING BLOOD SUGAR. COMPARISON BETWEEN STM AND LTM SHOWED THAT THE CHANGES FROM BASELINE VALUES (FROM PREMEDITATION TO POST-MEDITATION AT 15 AND 30 MINUTES) IN LTM WERE NOT STATISTICALLY SIGNIFICANT WITH THOSE IN STM (P > 0.05). HOWEVER, WITHIN GROUP DIFFERENCES IN LTM REVEALED THAT CHANGES IN THE PHYSIOLOGICAL VARIABLES WERE STATISTICALLY SIGNIFICANT WHEN COMPARED BETWEEN PRE AND POST MEDITATION BOTH AT 15 AND 30 MINUTES. THE STUDY SUGGESTS THAT THE LONG-TERM PRACTICE OF RAJA YOGA MEDITATION IMPROVES BASIC CARDIO-RESPIRATORY FUNCTIONS DUE TO SHIFTING OF THE AUTONOMIC BALANCE IN FAVOR OF PARASYMPATHETIC INSTEAD OF SYMPATHETIC SYSTEM.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
20   39  28 A BRIEF BUT COMPREHENSIVE LIFESTYLE EDUCATION PROGRAM BASED ON YOGA REDUCES RISK FACTORS FOR CARDIOVASCULAR DISEASE AND DIABETES MELLITUS. OBJECTIVES: THE OBJECTIVE OF THE STUDY WAS TO STUDY THE SHORT-TERM IMPACT OF A BRIEF LIFESTYLE INTERVENTION BASED ON YOGA ON SOME OF THE BIOCHEMICAL INDICATORS OF RISK FOR CARDIOVASCULAR DISEASE AND DIABETES MELLITUS. DESIGN: THE VARIABLES OF INTEREST WERE MEASURED AT THE BEGINNING (DAY 1) AND END (DAY 10) OF THE INTERVENTION USING A PRE-POST DESIGN. SETTING: THE STUDY IS THE RESULT OF OPERATIONAL RESEARCH CARRIED OUT IN OUR INTEGRAL HEALTH CLINIC (IHC). THE IHC IS AN OUTPATIENT FACILITY WHICH CONDUCTS 8-DAY LIFESTYLE MODIFICATION PROGRAMS BASED ON YOGA FOR PREVENTION AND MANAGEMENT OF CHRONIC DISEASE. A NEW COURSE BEGINS EVERY ALTERNATE WEEK OF THE YEAR. SUBJECTS: THE STUDY IS BASED ON DATA COLLECTED ON 98 SUBJECTS (67 MALE, 31 FEMALE), AGES 20-74 YEARS, WHO ATTENDED ONE OF OUR PROGRAMS. THE SUBJECTS WERE A HETEROGENEOUS GROUP OF PATIENTS WITH HYPERTENSION, CORONARY ARTERY DISEASE, DIABETES MELLITUS, AND A VARIETY OF OTHER ILLNESSES. INTERVENTION: THE INTERVENTION CONSISTED OF ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), RELAXATION TECHNIQUES, GROUP SUPPORT, INDIVIDUALIZED ADVICE, LECTURES AND FILMS ON THE PHILOSOPHY OF YOGA AND THE PLACE OF YOGA IN DAILY LIFE, MEDITATION, STRESS MANAGEMENT, NUTRITION, AND KNOWLEDGE ABOUT THE ILLNESS. OUTCOME MEASURES: THE OUTCOME MEASURES WERE FASTING PLASMA GLUCOSE AND SERUM LIPOPROTEIN PROFILE. THESE VARIABLES WERE DETERMINED IN FASTING BLOOD SAMPLES, TAKEN ON THE FIRST AND LAST DAY OF THE COURSE. RESULTS: FASTING PLASMA GLUCOSE, SERUM TOTAL CHOLESTEROL, LOW-DENSITY LIPOPROTEIN (LDL) CHOLESTEROL, VERY- LDL CHOLESTEROL, THE RATIO OF TOTAL CHOLESTEROL TO HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL, AND TOTAL TRIGLYCERIDES WERE SIGNIFICANTLY LOWER, AND HDL CHOLESTEROL SIGNIFICANTLY HIGHER, ON THE LAST DAY OF THE COURSE COMPARED TO THE FIRST DAY OF THE COURSE. THE CHANGES WERE MORE MARKED IN SUBJECTS WITH HYPERGLYCEMIA OR HYPERCHOLESTEROLEMIA. CONCLUSIONS: THE OBSERVATIONS SUGGEST THAT A SHORT LIFESTYLE MODIFICATION AND STRESS MANAGEMENT EDUCATION PROGRAM LEADS TO FAVORABLE METABOLIC EFFECTS WITHIN A PERIOD OF 9 DAYS.	2005