1 2877 117 YOGA-SPECIFIC ENHANCEMENT OF QUALITY OF LIFE AMONG WOMEN WITH BREAST CANCER: SYSTEMATIC REVIEW AND EXPLORATORY META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. PHYSICAL ACTIVITIES DURING AND AFTER CANCER TREATMENT HAVE FAVORABLE PSYCHOSOCIAL EFFECTS. INCREASINGLY, YOGA HAS BECOME A POPULAR APPROACH TO IMPROVING THE QUALITY OF LIFE (QOL) OF WOMEN WITH BREAST CANCER. HOWEVER, THE EXTANT SYNTHETIC EVIDENCE ON YOGA HAS NOT USED OTHER EXERCISE COMPARISON CONDITIONS. THIS META-ANALYSIS AIMED TO SYSTEMATICALLY ASSESS YOGA-SPECIFIC EFFECTS RELATIVE TO ANY OTHER PHYSICAL EXERCISE INTERVENTION (EG, AEROBICS) FOR WOMEN WITH BREAST CANCER. QOL WAS THE PRIMARY OUTCOME OF INTEREST. EIGHT RANDOMIZED CONTROLLED TRIALS WITH 545 PARTICIPANTS WERE INCLUDED. THE SAMPLE-WEIGHTED SYNTHESIS AT IMMEDIATE POSTINTERVENTION REVEALED MARGINALLY STATISTICALLY AND MODEST PRACTICALLY SIGNIFICANT DIFFERENCES SUGGESTING YOGA'S POTENTIALLY GREATER EFFECTIVENESS: D = 0.14, P = .10. HOWEVER, AT LONGER TERM FOLLOW-UP, NO STATISTICALLY OR PRACTICALLY SIGNIFICANT BETWEEN-GROUP DIFFERENCE WAS OBSERVED. THIS META-ANALYSIS PRELIMINARILY DEMONSTRATED THAT YOGA IS PROBABLY AS EFFECTIVE AS OTHER EXERCISE MODALITIES IN IMPROVING THE QOL OF WOMEN WITH BREAST CANCER. BOTH INTERVENTIONS WERE ASSOCIATED WITH CLINICALLY SIGNIFICANT IMPROVEMENTS IN QOL. NEARLY ALL OF THE YOGA INTERVENTION PROGRAMS, HOWEVER, WERE VERY POORLY RESOURCED. LARGER AND BETTER CONTROLLED TRIALS OF WELL-ENDOWED YOGA PROGRAMS ARE NEEDED.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
2 1740  37 PHYSICAL AND PSYCHOSOCIAL BENEFITS OF YOGA IN CANCER PATIENTS AND SURVIVORS, A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: THIS STUDY AIMED TO SYSTEMATICALLY REVIEW THE EVIDENCE FROM RANDOMIZED CONTROLLED TRIALS (RCTS) AND TO CONDUCT A META-ANALYSIS OF THE EFFECTS OF YOGA ON PHYSICAL AND PSYCHOSOCIAL OUTCOMES IN CANCER PATIENTS AND SURVIVORS. METHODS: A SYSTEMATIC LITERATURE SEARCH IN TEN DATABASES WAS CONDUCTED IN NOVEMBER 2011. STUDIES WERE INCLUDED IF THEY HAD AN RCT DESIGN, FOCUSED ON CANCER PATIENTS OR SURVIVORS, INCLUDED PHYSICAL POSTURES IN THE YOGA PROGRAM, COMPARED YOGA WITH A NON-EXERCISE OR WAITLIST CONTROL GROUP, AND EVALUATED PHYSICAL AND/OR PSYCHOSOCIAL OUTCOMES. TWO RESEARCHERS INDEPENDENTLY RATED THE QUALITY OF THE INCLUDED RCTS, AND HIGH QUALITY WAS DEFINED AS >50% OF THE TOTAL POSSIBLE SCORE. EFFECT SIZES (COHEN'S D) WERE CALCULATED FOR OUTCOMES STUDIED IN MORE THAN THREE STUDIES AMONG PATIENTS WITH BREAST CANCER USING MEANS AND STANDARD DEVIATIONS OF POST-TEST SCORES OF THE INTERVENTION AND CONTROL GROUPS. RESULTS: SIXTEEN PUBLICATIONS OF 13 RCTS MET THE INCLUSION CRITERIA, OF WHICH ONE INCLUDED PATIENTS WITH LYMPHOMAS AND THE OTHERS FOCUSED ON PATIENTS WITH BREAST CANCER. THE MEDIAN QUALITY SCORE WAS 67% (RANGE: 22-89%). THE INCLUDED STUDIES EVALUATED 23 PHYSICAL AND 20 PSYCHOSOCIAL OUTCOMES. OF THE OUTCOMES STUDIED IN MORE THAN THREE STUDIES AMONG PATIENTS WITH BREAST CANCER, WE FOUND LARGE REDUCTIONS IN DISTRESS, ANXIETY, AND DEPRESSION (D = -0.69 TO -0.75), MODERATE REDUCTIONS IN FATIGUE (D = -0.51), MODERATE INCREASES IN GENERAL QUALITY OF LIFE, EMOTIONAL FUNCTION AND SOCIAL FUNCTION (D = 0.33 TO 0.49), AND A SMALL INCREASE IN FUNCTIONAL WELL-BEING (D = 0.31). EFFECTS ON PHYSICAL FUNCTION AND SLEEP WERE SMALL AND NOT SIGNIFICANT. CONCLUSION: YOGA APPEARED TO BE A FEASIBLE INTERVENTION AND BENEFICIAL EFFECTS ON SEVERAL PHYSICAL AND PSYCHOSOCIAL SYMPTOMS WERE REPORTED. IN PATIENTS WITH BREAST CANCER, EFFECT SIZE ON FUNCTIONAL WELL-BEING WAS SMALL, AND THEY WERE MODERATE TO LARGE FOR PSYCHOSOCIAL OUTCOMES.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
3 2609  53 YOGA FOR QUALITY OF LIFE IN INDIVIDUALS WITH CHRONIC DISEASE: A SYSTEMATIC REVIEW. BACKGROUND: CHRONIC DISEASES, INCLUDING HEART DISEASE, STROKE, CANCER, AND CHRONIC PULMONARY DISEASE ARE THE LEADING CAUSES OF DEATH AND DISABILITY WORLDWIDE. COMPOUNDING SYMPTOMS AND LOSS OF FUNCTION, PEOPLE LIVING WITH CHRONIC DISEASE OFTEN EXPERIENCE REDUCED QUALITY OF LIFE (QOL). VARIOUS PHYSICAL AND MENTAL PRACTICES HAVE BEEN SHOWN TO RELIEVE STRESS AND IMPROVE QOL. YOGA IS A PHYSICAL AND MENTAL PRACTICE THAT MAY BE A VIABLE APPROACH FOR IMPROVING QOL IN PEOPLE WITH CHRONIC DISEASE. OBJECTIVE: THE OBJECTIVE OF THIS STUDY WAS TO EXAMINE AND SUMMARIZE THE EVIDENCE FOR THE EFFECTIVENESS OF YOGA ON QOL IN PATIENTS WITH CHRONIC DISEASE. DESIGN: THE STUDY DESIGN WAS A A SYSTEMATIC REVIEW WITH QUALITATIVE SYNTHESIS. METHODS: WE INCLUDED RANDOMIZED CONTROLLED TRIALS THAT EVALUATED THE EFFECT OF YOGA ON QOL OR HEALTH-RELATED QOL (HRQOL) FOR INDIVIDUALS WITH CHRONIC DISEASE. WE INCLUDED ONLY STUDIES THAT USED AT LEAST 1 PREVIOUSLY VALIDATED MEASURE OF QOL OR HRQOL AND SPECIFIED A MINIMUM DURATION OF FOLLOW-UP OF AT LEAST 1 WK. INTERVENTIONS: WE INCLUDED BOTH MOVEMENT-BASED AND BREATH-BASED YOGA PRACTICES. STUDIES THAT INCLUDED YOGA AS PART OF A LARGER INTERVENTION PROGRAM (EG, MINDFULNESS-BASED STRESS REDUCTION TRAINING) OR STUDIES THAT DID NOT PROVIDE FINDINGS SPECIFIC TO YOGA WERE EXCLUDED. PRIMARY OUTCOME MEASURES: THE PRIMARY OUTCOME ANALYZED WAS IMPROVEMENT IN QOL AS MEASURED BY A VALIDATED QOL OR HRQOL SCALE. RESULTS: AMONG THE 1488 STUDIES THAT WERE IDENTIFIED ON INITIAL SEARCH, 7 ARTICLES MET ALL INCLUSION CRITERIA. FIVE STUDIES REPORTED A STATISTICALLY SIGNIFICANT ADVANTAGE OVER USUAL CARE ALONE FOR IMPROVEMENT OF QOL IN PATIENTS WITH CHRONIC DISEASE, BUT THE CLINICAL SIGNIFICANCE OF THE DIFFERENCES WAS CLEAR IN ONLY 1 TRIAL. WE FOUND CONSIDERABLE HETEROGENEITY AMONG THE INCLUDED STUDIES AND STUDY QUALITY WAS GENERALLY LOW. CONCLUSIONS: MORE HIGH-QUALITY RESEARCH IS NEEDED TO DETERMINE THE VALUE OF YOGA AS AN ADJUNCTIVE APPROACH TO IMPROVING QOL IN PATIENTS WITH CHRONIC DISEASE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
4 1079  33 EFFECTS OF YOGA ON PSYCHOLOGICAL HEALTH, QUALITY OF LIFE, AND PHYSICAL HEALTH OF PATIENTS WITH CANCER: A META-ANALYSIS. YOGA IS ONE OF THE MOST WIDELY USED COMPLEMENTARY AND ALTERNATIVE MEDICINE THERAPIES TO MANAGE ILLNESS. THIS META-ANALYSIS AIMED TO DETERMINE THE EFFECTS OF YOGA ON PSYCHOLOGICAL HEALTH, QUALITY OF LIFE, AND PHYSICAL HEALTH OF PATIENTS WITH CANCER. STUDIES WERE IDENTIFIED THROUGH A SYSTEMATIC SEARCH OF SEVEN ELECTRONIC DATABASES AND WERE SELECTED IF THEY USED A RANDOMIZED CONTROLLED TRIAL DESIGN TO EXAMINE THE EFFECTS OF YOGA IN PATIENTS WITH CANCER. THE QUALITY OF EACH ARTICLE WAS RATED BY TWO OF THE AUTHORS USING THE PEDRO SCALE. TEN ARTICLES WERE SELECTED; THEIR PEDRO SCORES RANGED FROM 4 TO 7. THE YOGA GROUPS COMPARED TO WAITLIST CONTROL GROUPS OR SUPPORTIVE THERAPY GROUPS SHOWED SIGNIFICANTLY GREATER IMPROVEMENTS IN PSYCHOLOGICAL HEALTH: ANXIETY (P = .009), DEPRESSION (P = .002), DISTRESS (P = .003), AND STRESS (P = .006). HOWEVER, DUE TO THE MIXED AND LOW TO FAIR QUALITY AND SMALL NUMBER OF STUDIES CONDUCTED, THE FINDINGS ARE PRELIMINARY AND LIMITED AND SHOULD BE CONFIRMED THROUGH HIGHER-QUALITY, RANDOMIZED CONTROLLED TRIALS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
5  559  48 COULD YOGA PRACTICE IMPROVE TREATMENT-RELATED SIDE EFFECTS AND QUALITY OF LIFE FOR WOMEN WITH BREAST CANCER? A SYSTEMATIC REVIEW AND META-ANALYSIS. AIM: TO DETERMINE IF YOGA AS A COMPLEMENTARY AND ALTERNATIVE THERAPY WAS ASSOCIATED WITH ENHANCED HEALTH AND TREATMENT-RELATED SIDE EFFECTS IN PATIENTS WITH BREAST CANCER. THIS SYSTEMATIC REVIEW EXAMINES WHETHER YOGA PRACTICE PROVIDES ANY MEASURABLE BENEFIT, BOTH PHYSICALLY AND PSYCHOLOGICALLY, FOR WOMEN WITH BREAST CANCER. METHODS: PUBMED, EMBASE AND THE COCHRANE LIBRARY FOR RANDOMIZED CONTROLLED TRIALS (RCTS) THROUGHOUT JUNE 2013. WE EVALUATED THE QUALITY OF THE INCLUDED STUDIES BY THE COCHRANE HANDBOOK 5.2 STANDARDS AND ANALYZED THE DATA USING THE STATA SOFTWARE, VERSION 10.0. META-REGRESSION AND SUBGROUP ANALYSIS WERE ALSO PERFORMED TO IDENTIFY ADDITIONAL PREDICTORS OF OUTCOME AND TO ASSESS HETEROGENEITY. RESULTS: SIXTEEN RCTS WITH A TOTAL OF 930 PARTICIPANTS WERE INCLUDED. COMPARING YOGA GROUPS TO CONTROL GROUPS, THERE WAS A STATISTICALLY SIGNIFICANT DIFFERENCE IN OVERALL HEALTH-RELATED QUALITY OF LIFE, DEPRESSION, ANXIETY AND GASTROINTESTINAL SYMPTOMS. META-REGRESSION ANALYSES REVEALED THAT THE DURATION OF YOGA PRACTICE AND TYPE OF CONTROL GROUP PARTLY EXPLAINED THE HETEROGENEITY. SUBGROUP ANALYSES REVEALED THAT YOGA HAD A POSITIVE EFFECT ON ANXIETY ONLY WHEN IT HAD BEEN PRACTICED FOR LONGER THAN 3 MONTHS. ONLY THE WAIT-LIST CONTROL GROUP SHOWED AN EFFECT OF YOGA ON PHYSICAL WELL-BEING. CONCLUSION: THE CURRENT EVIDENCE DEMONSTRATES THAT YOGA PRACTICE COULD BE EFFECTIVE IN ENHANCING HEALTH AND MANAGING SOME TREATMENT-RELATED SIDE EFFECTS FOR PATIENTS RECOVERING FROM BREAST CANCER. IN FUTURE CLINICAL STUDIES, CLINICIANS SHOULD CONSIDER THE PATIENT'S WISHES ALONG WITH THE CURRENT BEST EVIDENCE OF THE EFFECTS OF YOGA PRACTICE IN THEIR CLINICAL DECISION-MAKING.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
6 2230  44 THE IMPACT OF YOGA ON FATIGUE IN CANCER SURVIVORSHIP: A META-ANALYSIS. BACKGROUND: MIND-BODY APPROACHES, PARTICULARLY YOGA, ARE USED BY CANCER SURVIVORS TO COPE WITH TREATMENT-RELATED SYMPTOMS. CONSISTENCY OF YOGA-RELATED EFFECTS ON TREATMENT-RELATED SYMPTOMS ARE NOT KNOWN. THIS META-ANALYSIS WAS DESIGNED TO EXAMINE EFFECTS OF YOGA ON PRE- TO POSTINTERVENTION IMPROVEMENTS IN FATIGUE AMONG CANCER PATIENTS. METHODS: PUBMED AND PSYCINFO WERE SEARCHED FOR PEER-REVIEWED ARTICLES OF YOGA RANDOMIZED CONTROLLED TRIALS INCLUDING CANCER SURVIVORS AND REPORTING AT LEAST ONE FATIGUE MEASURE. TWENTY-NINE STUDIES MET INCLUSION CRITERIA (N = 1828 PATIENTS). EFFECT SIZES (HEDGE'S G) WERE CALCULATED FOR FATIGUE, DEPRESSION, AND QUALITY OF LIFE. PATIENT-RELATED AND INTERVENTION-RELATED CHARACTERISTICS WERE TESTED AS MODERATORS OF OUTCOMES. ALL STATISTICAL TESTS WERE TWO-SIDED. RESULTS: YOGA PRACTICE WAS ASSOCIATED WITH A SMALL, STATISTICALLY SIGNIFICANT DECREASE IN FATIGUE (G = 0.45, P = .013). YOGA TYPE WAS A STATISTICALLY SIGNIFICANT MODERATOR OF THIS RELATIONSHIP (P = .02). YOGA WAS ASSOCIATED WITH A MODERATE DECREASE IN DEPRESSION (G = 0.72, P = .007) BUT WAS NOT ASSOCIATED WITH STATISTICALLY SIGNIFICANT CHANGES IN QUALITY OF LIFE (P = .48). SESSION LENGTH WAS A STATISTICALLY SIGNIFICANT MODERATOR OF THE RELATIONSHIP BETWEEN YOGA AND DEPRESSION (P = .004). NEITHER TIMING OF TREATMENT (DURING TREATMENT VS POSTTREATMENT) NOR CLINICAL CHARACTERISTICS WERE STATISTICALLY SIGNIFICANT MODERATORS OF THE EFFECTS OF YOGA ON OUTCOMES. THE EFFECT OF YOGA ON FATIGUE AND DEPRESSION WAS LARGER WHEN THE COMPARATOR WAS A "WAITLIST" OR "USUAL CARE" THAN WHEN THE CONTROL GROUP WAS ANOTHER ACTIVE TREATMENT (P = .036). CONCLUSIONS: RESULTS SUGGEST YOGA MAY BE BENEFICIAL AS A COMPONENT OF TREATMENT FOR BOTH FATIGUE AND DEPRESSION IN CANCER SURVIVORS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
7 2623  41 YOGA FOR SYMPTOM MANAGEMENT IN ONCOLOGY: A REVIEW OF THE EVIDENCE BASE AND FUTURE DIRECTIONS FOR RESEARCH. BECAUSE YOGA IS INCREASINGLY RECOGNIZED AS A COMPLEMENTARY APPROACH TO CANCER SYMPTOM MANAGEMENT, PATIENTS/SURVIVORS AND PROVIDERS NEED TO UNDERSTAND ITS POTENTIAL BENEFITS AND LIMITATIONS BOTH DURING AND AFTER TREATMENT. THE AUTHORS REVIEWED RANDOMIZED CONTROLLED TRIALS (RCTS) OF YOGA CONDUCTED AT THESE POINTS IN THE CANCER CONTINUUM (N = 29; N = 13 DURING TREATMENT, N = 12 POST-TREATMENT, AND N = 4 WITH MIXED SAMPLES). FINDINGS BOTH DURING AND AFTER TREATMENT DEMONSTRATED THE EFFICACY OF YOGA TO IMPROVE OVERALL QUALITY OF LIFE (QOL), WITH IMPROVEMENT IN SUBDOMAINS OF QOL VARYING ACROSS STUDIES. FATIGUE WAS THE MOST COMMONLY MEASURED OUTCOME, AND MOST RCTS CONDUCTED DURING OR AFTER CANCER TREATMENT REPORTED IMPROVEMENTS IN FATIGUE. RESULTS ALSO SUGGESTED THAT YOGA CAN IMPROVE STRESS/DISTRESS DURING TREATMENT AND POST-TREATMENT DISTURBANCES IN SLEEP AND COGNITION. SEVERAL RCTS PROVIDED EVIDENCE THAT YOGA MAY IMPROVE BIOMARKERS OF STRESS, INFLAMMATION, AND IMMUNE FUNCTION. OUTCOMES WITH LIMITED OR MIXED FINDINGS (EG, ANXIETY, DEPRESSION, PAIN, CANCER-SPECIFIC SYMPTOMS, SUCH AS LYMPHEDEMA) AND POSITIVE PSYCHOLOGICAL OUTCOMES (SUCH AS BENEFIT-FINDING AND LIFE SATISFACTION) WARRANT FURTHER STUDY. IMPORTANT FUTURE DIRECTIONS FOR YOGA RESEARCH IN ONCOLOGY INCLUDE: ENROLLING PARTICIPANTS WITH CANCER TYPES OTHER THAN BREAST, STANDARDIZING SELF-REPORT ASSESSMENTS, INCREASING THE USE OF ACTIVE CONTROL GROUPS AND OBJECTIVE MEASURES, AND ADDRESSING THE HETEROGENEITY OF YOGA INTERVENTIONS, WHICH VARY IN TYPE, KEY COMPONENTS (MOVEMENT, MEDITATION, BREATHING), DOSE, AND DELIVERY MODE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
8 1042  43 EFFECTS OF YOGA INTERVENTIONS ON FATIGUE IN CANCER PATIENTS AND SURVIVORS: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: FATIGUE IS ONE OF THE MOST FREQUENTLY REPORTED, DISTRESSING SIDE EFFECTS REPORTED BY CANCER SURVIVORS AND OFTEN HAS SIGNIFICANT LONG-TERM CONSEQUENCES. RESEARCH INDICATES THAT YOGA CAN PRODUCE INVIGORATING EFFECTS ON PHYSICAL AND MENTAL ENERGY, AND THEREBY MAY IMPROVE LEVELS OF FATIGUE. THE OBJECTIVE OF THIS SYSTEMATIC REVIEW WAS TO EXAMINE THE LITERATURE THAT REPORTS THE EFFECTS OF RANDOMIZED, CONTROLLED YOGA INTERVENTIONS ON SELF-REPORTED FATIGUE IN CANCER PATIENTS AND SURVIVORS. THE ONLINE ELECTRONIC DATABASES, PUBMED AND PSYCINFO, WERE USED TO SEARCH FOR PEER-REVIEWED RESEARCH ARTICLES STUDYING THE EFFECTS OF YOGA INTERVENTIONS ON FATIGUE IN CANCER SURVIVORS. COMBINATIONS OF YOGA, CANCER, AND FATIGUE-RELATED SEARCH TERMS WERE ENTERED SIMULTANEOUSLY TO OBTAIN ARTICLES THAT INCLUDED ALL THREE ELEMENTS. STUDIES WERE INCLUDED IF THEY MET THE FOLLOWING INCLUSION CRITERIA: PARTICIPANTS WERE MALE OR FEMALE CANCER PATIENTS OR SURVIVORS PARTICIPATING IN RANDOMIZED, CONTROLLED YOGA INTERVENTIONS. THE MAIN OUTCOME OF INTEREST WAS CHANGE IN FATIGUE FROM PRE- TO POST-INTERVENTION. INTERVENTIONS OF ANY LENGTH WERE INCLUDED IN THE ANALYSIS. RISK OF BIAS USING THE FORMAT OF THE COCHRANE COLLABORATION'S TOOL FOR ASSESSING RISK OF BIAS WAS ALSO EXAMINED ACROSS STUDIES. RESULTS: TEN ARTICLES MET INCLUSION CRITERIA AND INVOLVED A TOTAL OF 583 PARTICIPANTS WHO WERE PREDOMINANTLY FEMALE, BREAST CANCER SURVIVORS. FOUR STUDIES INDICATED THAT THE YOGA INTERVENTION RESULTED IN SIGNIFICANT REDUCTIONS IN SELF-REPORTED FATIGUE FROM PRE- TO POST-INTERVENTION. THREE OF THE STUDIES REPORTED THAT THERE WERE SIGNIFICANT REDUCTIONS OF FATIGUE AMONG PARTICIPANTS WHO ATTENDED A GREATER NUMBER OF YOGA CLASSES. RISK OF BIAS WAS HIGH FOR AREAS OF ADEQUATE SELECTION, PERFORMANCE, DETECTION, AND PATIENT-REPORTED BIAS AND MIXED FOR ATTRITION AND REPORTING BIAS. RISK OF BIAS WAS UNIFORMLY LOW FOR OTHER FORMS OF BIAS, INCLUDING FINANCIAL CONFLICTS OF INTEREST. CONCLUSIONS: RESULTS OF THE STUDIES INCLUDED IN THIS REVIEW SUGGEST THAT YOGA INTERVENTIONS MAY BE BENEFICIAL FOR REDUCING CANCER-RELATED FATIGUE IN WOMEN WITH BREAST CANCER; HOWEVER, CONCLUSIONS SHOULD BE INTERPRETED WITH CAUTION AS A RESULT OF LEVELS OF BIAS AND INCONSISTENT METHODS USED ACROSS STUDIES. MORE WELL-CONSTRUCTED RANDOMIZED CONTROLLED TRIALS ARE NEEDED TO DETERMINE THE IMPACT OF YOGA INTERVENTIONS ON FATIGUE IN CANCER PATIENTS AND SURVIVORS.	2013	

9 2383  32 YOGA & CANCER INTERVENTIONS: A REVIEW OF THE CLINICAL SIGNIFICANCE OF PATIENT REPORTED OUTCOMES FOR CANCER SURVIVORS. LIMITED RESEARCH SUGGESTS YOGA MAY BE A VIABLE GENTLE PHYSICAL ACTIVITY OPTION WITH A VARIETY OF HEALTH-RELATED QUALITY OF LIFE, PSYCHOSOCIAL AND SYMPTOM MANAGEMENT BENEFITS. THE PURPOSE OF THIS REVIEW WAS TO DETERMINE THE CLINICAL SIGNIFICANCE OF PATIENT-REPORTED OUTCOMES FROM YOGA INTERVENTIONS CONDUCTED WITH CANCER SURVIVORS. A TOTAL OF 25 PUBLISHED YOGA INTERVENTION STUDIES FOR CANCER SURVIVORS FROM 2004-2011 HAD PATIENT-REPORTED OUTCOMES, INCLUDING QUALITY OF LIFE, PSYCHOSOCIAL OR SYMPTOM MEASURES. THIRTEEN OF THESE STUDIES MET THE NECESSARY CRITERIA TO ASSESS CLINICAL SIGNIFICANCE. CLINICAL SIGNIFICANCE FOR EACH OF THE OUTCOMES OF INTEREST WAS EXAMINED BASED ON 1 STANDARD ERROR OF THE MEASUREMENT, 0.5 STANDARD DEVIATION, AND RELATIVE COMPARATIVE EFFECT SIZES AND THEIR RESPECTIVE CONFIDENCE INTERVALS. THIS REVIEW DESCRIBES IN DETAIL THESE PATIENT-REPORTED OUTCOMES, HOW THEY WERE OBTAINED, THEIR RELATIVE CLINICAL SIGNIFICANCE AND IMPLICATIONS FOR BOTH CLINICAL AND RESEARCH SETTINGS. OVERALL, CLINICALLY SIGNIFICANT CHANGES IN PATIENT-REPORTED OUTCOMES SUGGEST THAT YOGA INTERVENTIONS HOLD PROMISE FOR IMPROVING CANCER SURVIVORS' WELL-BEING. THIS RESEARCH OVERVIEW PROVIDES NEW DIRECTIONS FOR EXAMINING HOW CLINICAL SIGNIFICANCE CAN PROVIDE A UNIQUE CONTEXT FOR DESCRIBING CHANGES IN PATIENT-REPORTED OUTCOMES FROM YOGA INTERVENTIONS. RESEARCHERS ARE ENCOURAGED TO EMPLOY INDICES OF CLINICAL SIGNIFICANCE IN THE INTERPRETATION AND DISCUSSION OF RESULTS FROM YOGA STUDIES.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
10 2354  35 UTILIZING YOGA IN ONCOLOGIC PATIENTS TREATED WITH RADIOTHERAPY: REVIEW. PURPOSE: SEVERAL TRIALS ON NONCANCER POPULATION INDICATE THAT YOGA IS ASSOCIATED WITH MEANINGFUL CLINICAL EFFECTS. THIS STUDY EVALUATED THE PHYSICAL AND PSYCHOSOCIAL OUTCOMES OF YOGA IN ONCOLOGIC PATIENTS TREATED WITH RADIOTHERAPY. METHODS: WE FOCUSED ON A RESEARCH THROUGH COCHRANE REGISTER OF CONTROLLED TRIALS (CENTRAL), BIOMED CENTRAL, AND MEDLINE STUDIES UP TO MAY 2017. RESULTS: YOGA WAS FOUND TO HAVE A SUBSTANTIAL BENEFIT IN CANCER PATIENTS' DISTRESS, ANXIETY, AND DEPRESSION. IT ALSO DEMONSTRATED A MODERATE IMPACT ON FATIGUE AND EMOTIONAL FUNCTION AND A SMALL AND INSIGNIFICANT EFFECT ON FUNCTIONAL WELL-BEING AND SLEEP DISTURBANCES. AS FAR AS THE EFFECTS ON PSYCHOLOGICAL OUTCOMES ARE CONCERNED, THERE WAS INSUFFICIENT EVIDENCE. CONCLUSIONS: THIS SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS SHOWED THAT YOGA HAS STRONG BENEFICIAL EFFECTS ON ONCOLOGIC PATIENTS' QUALITY OF LIFE. RESULTS OF THE CURRENT REVIEW MUST BE INTERPRETED WITH CAUTION DUE TO THE RELATIVE SMALL SAMPLE SIZES OF MOST OF THE INCLUDED STUDIES, WHILE A PROSPECTIVE RANDOMIZED STUDY STANDS IN NEED FOR THE CONFIRMATION OF OUR RESULTS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
11 2365  36 WALKING IS MORE EFFECTIVE THAN YOGA AT REDUCING SLEEP DISTURBANCE IN CANCER PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. THIS REVIEW AIMED TO DETERMINE WHETHER WALKING IS MORE EFFECTIVE THAN YOGA AT IMPROVING SLEEP DISTURBANCE IN CANCER PATIENTS. A SYSTEMATIC SEARCH OF RANDOMIZED CONTROLLED TRIALS WAS PERFORMED IN THE PUBMED, EMBASE, CINAHL, COCHRANE LIBRARY, CNKI, AIRITI LIBRARY, AND OTHER HEALTH-RELATED DATABASES. TWENTY-FIVE STUDIES WERE IDENTIFIED WITH A TOTAL OF 1918 PARTICIPANTS. THE PITTSBURGH SLEEP QUALITY INDEX WAS THE MOST COMMONLY USED OUTCOME MEASUREMENT TOOL, AND MODERATE-INTENSITY WALKING WAS THE MOST FREQUENTLY USED INTERVENTION. THE MAJORITY OF THE INCLUDED SUBJECTS WERE BREAST CANCER PATIENTS. OVERALL, WALKING SIGNIFICANTLY IMPROVED SLEEP DISTURBANCE COMPARED TO YOGA (P = 0.01). STATISTICALLY SIGNIFICANT MODERATORS INCLUDED ADHERENCE RATE FOR WALKING (P < 0.001) AND ALLOCATION CONCEALMENT AND OUTCOME MEASUREMENT TOOL FOR YOGA (P = 0.04; P = 0.03). WE CONCLUDED THAT WALKING IS MORE EFFECTIVE THAN YOGA IN IMPROVING SLEEP DISTURBANCE IN CANCER PATIENTS. THUS, MODERATE-INTENSITY WALKING IS RECOMMENDED FOR CANCER PATIENTS WITH SLEEP DISTURBANCE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
12 2440  39 YOGA AND QUALITY-OF-LIFE IMPROVEMENT IN PATIENTS WITH BREAST CANCER: A LITERATURE REVIEW. OBJECTIVE: WOMEN UNDERGOING TREATMENT FOR BREAST CANCER OFTEN TURN TO COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM), INCLUDING YOGA, FOR IMPROVEMENT OF MOOD, QUALITY OF LIFE (QOL), SLEEP, AND TREATMENT-RELATED SIDE EFFECTS. THE EXTANT LITERATURE WAS REVIEWED TO EXAMINE THE CLINICAL EFFECTS OF YOGA PRACTICE ON QOL FOR PATIENTS WITH BREAST CANCER. QOL WAS DEFINED AS PHYSICAL WELL-BEING, SOCIAL FUNCTIONING, EMOTIONAL HEALTH, AND FUNCTION-AL ADAPTATION. METHODS: SEVEN DATABASES, INCLUDING PUBMED, OVID MEDLINE, CINAHL, EMBASE, PSYCINFO, COCHRANE LIBRARY, AND WEB OF SCIENCE WERE USED TO SEARCH FOR STUDIES OF PATIENTS WITH BREAST CANCER THAT INCLUDED A YOGA INTERVENTION AND QOL ASSESSMENT. ATTENTION WAS PAID TO ASSESSING STUDY POPULATION, OUTCOME VARIABLES, THE TYPE OF YOGA INTERVENTION USED, AND METHODOLOGICAL STRENGTHS AND LIMITATIONS. RESULTS: SEVENTY-ONE ARTICLES WERE IDENTIFIED THAT FIT THE SEARCH CRITERIA. ALTHOUGH THE LITERATURE PROVIDED EVIDENCE OF QOL BENEFITS OF YOGA FOR PATIENTS WITH BREAST CANCER, NO SPECIFIC ASPECT OF YOGA WAS IDENTIFIED AS BEING MOST ADVANTAGEOUS. CONCLUSION: ALTHOUGH PARTICIPATION IN YOGA PROGRAMS APPEARED TO BENEFIT PATIENTS WITH BREAST CANCER, GREATER METHODOLOGICAL RIGOR IS REQUIRED TO UNDERSTAND THE MECHANISMS THAT CONTRIBUTE TO THEIR EFFECTIVENESS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
13 2592  36 YOGA FOR MENOPAUSAL SYMPTOMS: A SYSTEMATIC REVIEW. OBJECTIVE: THE AIM OF THIS STUDY WAS TO ASSESS THE EFFECTIVENESS OF YOGA AS A TREATMENT OPTION FOR MENOPAUSAL SYMPTOMS. METHODS: WE SEARCHED THE LITERATURE USING 14 DATABASES FROM THEIR INCEPTION TO JULY 2008 AND INCLUDED ALL TYPES OF CLINICAL STUDIES REGARDLESS OF THEIR DESIGN. THE METHODOLOGICAL QUALITY OF ALL STUDIES WAS ASSESSED USING A MODIFIED JADAD SCORE. RESULTS: SEVEN STUDIES MET OUR INCLUSION CRITERIA. TWO RANDOMIZED CLINICAL TRIALS COMPARED THE EFFECTS OF YOGA WITH THOSE OF WALKING OR PHYSICAL EXERCISE. THE META-ANALYSIS OF THESE DATA FAILED TO SHOW SPECIFIC EFFECTS OF YOGA ON MENOPAUSAL COMPLAINTS INCLUDING PSYCHOLOGICAL, SOMATIC, AND VASOMOTOR SYMPTOMS. TWO RANDOMIZED CLINICAL TRIALS FOUND NO EFFECTS OF YOGA ON TOTAL MENOPAUSAL SYMPTOMS COMPARED WITH WAIT-LIST CONTROL OR NO TREATMENT. THE REMAINING STUDIES WERE EITHER NON-RANDOMIZED (N = 1) OR UNCONTROLLED CLINICAL TRIALS (N = 3). THEY REPORTED FAVORABLE EFFECTS OF YOGA ON MENOPAUSAL SYMPTOMS. THESE DATA COLLECTIVELY SHOW THAT THE RESULTS OF RIGOROUS STUDIES OF THE EFFECTS OF YOGA FOR MENOPAUSAL SYMPTOMS ARE UNCONVINCING. CONCLUSION: THE EVIDENCE IS INSUFFICIENT TO SUGGEST THAT YOGA IS AN EFFECTIVE INTERVENTION FOR MENOPAUSE. FURTHER RESEARCH IS REQUIRED TO INVESTIGATE WHETHER THERE ARE SPECIFIC BENEFITS OF YOGA FOR TREATING MENOPAUSAL SYMPTOMS.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
14 1124  41 EFFICACY OF PRENATAL YOGA IN THE TREATMENT OF DEPRESSION AND ANXIETY DURING PREGNANCY: A SYSTEMATIC REVIEW AND META-ANALYSIS. WOMEN COMMONLY SUFFER FROM DEPRESSION DURING PREGNANCY. FOR REDUCING DEPRESSION, YOGA SEEMS TO BE MORE SUITABLE FOR PREGNANT WOMEN THAN OTHER PHYSICAL ACTIVITIES BECAUSE OF ITS LOW EXERCISE INTENSITY. THE OBJECTIVE OF THIS STUDY WAS TO ASSESS THE EFFICACY OF PRENATAL YOGA ON THE TREATMENT OF DEPRESSION DURING PREGNANCY. THREE ELECTRONIC DATABASES WERE SEARCHED FOR RELEVANT ARTICLES FROM THEIR INCEPTION TO MAY 2021, INCLUDING PUBMED, COCHRANE LIBRARY, AND SCIENCEDIRECT. PRE- AND POST-TEST OUTCOMES WERE ADOPTED TO ESTIMATE STANDARDIZED MEAN DIFFERENCE WITH A 95% CONFIDENCE INTERVAL FOR ASSESSING THE EFFICACY OF YOGA. HETEROGENEITY AMONG ARTICLES WAS DETECTED USING I(2) VALUE. A TOTAL OF 13 ARTICLES THAT CONTAINED 379 SUBJECTS WERE INCLUDED FOR META-ANALYSIS. NO SIGNIFICANT IMPROVEMENT IN DEPRESSION SCORES AFTER PRACTICING YOGA WAS OBSERVED FOR WOMEN WITHOUT DEPRESSION (P = 0.09) BUT SIGNIFICANT IMPROVEMENT WAS OBSERVED FOR WOMEN WITH DEPRESSION (P = 0.001). ALTHOUGH SIGNIFICANT IMPROVEMENT IN ANXIETY SCORES AFTER YOGA WAS OBSERVED FOR WOMEN WITHOUT DEPRESSION (P = 0.02), THE RESULTS OF THE SENSITIVITY ANALYSIS WERE NOT CONSISTENT, WHILE SIGNIFICANT IMPROVEMENT IN ANXIETY SCORES AFTER YOGA WAS ALSO OBSERVED FOR WOMEN WITH DEPRESSION (P &LT; 0.00001). THE CURRENT EVIDENCE HAS SUGGESTED THAT YOGA HAD SIGNIFICANT IMPROVEMENT IN DEPRESSION AND ANXIETY SCORES IN PREGNANT WOMEN WITH DEPRESSION. HOWEVER, THE LEVEL OF EVIDENCE OF THIS STUDY WAS NOT HIGH. MORE ARTICLES WITH HIGH LEVELS OF EVIDENCE SHOULD BE CONDUCTED TO CONFIRM OUR CONCLUSION IN THE FUTURE.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
15 1077  42 EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION AND QUALITY OF LIFE IN WOMEN WITH BREAST CANCER: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. OBJECTIVE: THE AIM OF THIS META-ANALYSIS WAS TO EVALUATE THE EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION AND QUALITY OF LIFE (QOL) IN WOMEN WITH BREAST CANCER. DESIGN: A SYSTEMATIC SEARCH OF PUBMED, EMBASE, THE COCHRANE LIBRARY, THE CHINESE BIOMEDICAL LITERATURE DATABASE, AND THE CHINESE DIGITAL JOURNALS FULL-TEXT DATABASE WAS CARRIED OUT. RANDOMIZED CONTROL TRIALS (RCTS) EXAMINING THE EFFECTS OF YOGA, VERSUS A CONTROL GROUP RECEIVING NO INTERVENTION, ON PSYCHOLOGIC FUNCTIONING AND QOL IN WOMEN WITH BREAST CANCER WERE INCLUDED. METHODOLOGICAL QUALITY OF INCLUDED RCTS WAS ASSESSED ACCORDING TO THE COCHRANE HANDBOOK FOR SYSTEMATIC REVIEWS OF INTERVENTIONS 5.0.1, AND DATA WERE ANALYZED USING THE COCHRANE COLLABORATION'S REVIEW MANAGER 5.1. RESULTS: SIX (6) STUDIES INVOLVING 382 PATIENTS WERE INCLUDED. THE META-ANALYSIS SHOWED THAT YOGA CAN IMPROVE QOL FOR WOMEN WITH BREAST CANCER. A STATISTICALLY SIGNIFICANT EFFECT FAVORING YOGA FOR THE OUTCOME OF QOL WAS FOUND (STANDARD MEAN DIFFERENCE=0.27, 95% CONFIDENCE INTERVAL [0.02, 0.52], P=0.03). ALTHOUGH THE EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION OUTCOMES--SUCH AS ANXIETY, DEPRESSION, DISTRESS AND SLEEP--WERE IN THE EXPECTED DIRECTION, THESE EFFECTS WERE NOT STATISTICALLY SIGNIFICANT (P>0.05). FATIGUE SHOWED NO SIGNIFICANT DIFFERENCE (P>0.05). CONCLUSIONS: THE PRESENT DATA PROVIDED LITTLE INDICATION OF HOW EFFECTIVE YOGA MIGHT BE WHEN THEY WERE APPLIED BY WOMEN WITH BREAST CANCER EXCEPT FOR MILDLY EFFECTIVE IN QOL IMPROVEMENT. THE FINDINGS WERE BASED ON A SMALL BODY OF EVIDENCE IN WHICH METHODOLOGICAL QUALITY WAS NOT HIGH. FURTHER WELL-DESIGNED RCTS WITH LARGE SAMPLE SIZE ARE NEEDED TO CLARIFY THE UTILITY OF YOGA PRACTICE FOR THIS POPULATION.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
16 1945  37 SALUTE TO THE SUN: A NEW DAWN IN YOGA THERAPY FOR BREAST CANCER. INTRODUCTION: INTEREST IN THE APPLICATION OF YOGA FOR HEALTH BENEFITS IN WESTERN MEDICINE IS GROWING RAPIDLY, WITH A SIGNIFICANT RISE IN PUBLICATIONS. THE PURPOSE OF THIS SYSTEMATIC REVIEW IS TO DETERMINE WHETHER THE INCLUSION OF YOGA THERAPY TO THE TREATMENT OF BREAST CANCER CAN IMPROVE THE PATIENT'S PHYSICAL AND PSYCHOSOCIAL QUALITY OF LIFE (QOL). METHODS: A SEARCH OF PEER REVIEWED JOURNAL ARTICLES PUBLISHED BETWEEN JANUARY 2009 AND JULY 2014 WAS CONDUCTED. STUDIES WERE INCLUDED IF THEY HAD MORE THAN 15 STUDY PARTICIPANTS, INCLUDED INTERVENTIONS SUCH AS MINDFULNESS-BASED STRESS REDUCTION (MBSR) OR YOGA THERAPY WITH OR WITHOUT COMPARISON GROUPS AND HAD STATED PHYSICAL OR PSYCHOLOGICAL OUTCOMES. RESULTS: SCREENING IDENTIFIED 38 APPROPRIATE ARTICLES. THE MOST REPORTED PSYCHOSOCIAL BENEFITS OF YOGA THERAPY WERE ANXIETY, EMOTIONAL AND SOCIAL FUNCTIONING, STRESS, DEPRESSION AND GLOBAL QOL. THE MOST REPORTED PHYSICAL BENEFITS OF YOGA THERAPY WERE IMPROVED SALIVARY CORTISOL READINGS, SLEEP QUALITY AND LYMPHOCYTE APOPTOSIS. BENEFITS IN THESE AREAS WERE LINKED STRONGLY WITH THE YOGA INTERVENTIONS, IN ADDITION TO SIGNIFICANT IMPROVEMENT IN OVERALL QOL. CONCLUSION: THE EVIDENCE SUPPORTS THE USE OF YOGA THERAPY TO IMPROVE THE PHYSICAL AND PSYCHOSOCIAL QOL FOR BREAST CANCER PATIENTS WITH A RANGE OF BENEFITS RELEVANT TO RADIATION THERAPY. FUTURE STUDIES ARE RECOMMENDED TO CONFIRM THESE BENEFITS. EVIDENCE-BASED RECOMMENDATIONS FOR IMPLEMENTATION OF A YOGA THERAPY PROGRAMME HAVE BEEN DERIVED AND INCLUDED WITHIN THIS REVIEW. LONG-TERM FOLLOW-UP IS NECESSARY WITH THESE PROGRAMMES TO ASSESS THE EFFICACY OF THE YOGA INTERVENTION IN TERMS OF SUSTAINABILITY AND PATIENT OUTCOMES.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
17 1907  42 REVIEW OF YOGA THERAPY DURING CANCER TREATMENT. PURPOSE: REVIEWS OF YOGA RESEARCH THAT DISTINGUISH RESULTS OF TRIALS CONDUCTED DURING (VERSUS AFTER) CANCER TREATMENT ARE NEEDED TO GUIDE FUTURE RESEARCH AND CLINICAL PRACTICE. WE THEREFORE CONDUCTED A REVIEW OF NON-RANDOMIZED STUDIES AND RANDOMIZED CONTROLLED TRIALS OF YOGA INTERVENTIONS FOR CHILDREN AND ADULTS UNDERGOING TREATMENT FOR ANY CANCER TYPE. METHODS: STUDIES WERE IDENTIFIED VIA RESEARCH DATABASES AND REFERENCE LISTS. INCLUSION CRITERIA WERE THE FOLLOWING: (1) CHILDREN OR ADULTS UNDERGOING CANCER TREATMENT, (2) INTERVENTION STATED AS YOGA OR COMPONENT OF YOGA, AND (3) PUBLICATION IN ENGLISH IN PEER-REVIEWED JOURNALS THROUGH OCTOBER 2015. EXCLUSION CRITERIA WERE THE FOLLOWING: (1) SAMPLES RECEIVING HORMONE THERAPY ONLY, (2) INTERVENTIONS INVOLVING MEDITATION ONLY, AND (3) YOGA DELIVERED WITHIN BROADER CANCER RECOVERY OR MINDFULNESS-BASED STRESS REDUCTION PROGRAMS. RESULTS: RESULTS OF NON-RANDOMIZED (ADULT N = 8, PEDIATRIC N = 4) AND RANDOMIZED CONTROLLED TRIALS (ADULT N = 13, PEDIATRIC N = 0) CONDUCTED DURING CANCER TREATMENT ARE SUMMARIZED SEPARATELY BY AGE GROUP. FINDINGS MOST CONSISTENTLY SUPPORT IMPROVEMENT IN PSYCHOLOGICAL OUTCOMES (E.G., DEPRESSION, DISTRESS, ANXIETY). SEVERAL STUDIES ALSO FOUND THAT YOGA ENHANCED QUALITY OF LIFE, THOUGH FURTHER INVESTIGATION IS NEEDED TO CLARIFY DOMAIN-SPECIFIC EFFICACY (E.G., PHYSICAL, SOCIAL, CANCER-SPECIFIC). REGARDING PHYSICAL AND BIOMEDICAL OUTCOMES, EVIDENCE INCREASINGLY SUGGESTS THAT YOGA AMELIORATES SLEEP AND FATIGUE; ADDITIONAL RESEARCH IS NEEDED TO ADVANCE PRELIMINARY FINDINGS FOR OTHER TREATMENT SEQUELAE AND STRESS/IMMUNITY BIOMARKERS. CONCLUSIONS: AMONG ADULTS UNDERGOING CANCER TREATMENT, EVIDENCE SUPPORTS RECOMMENDING YOGA FOR IMPROVING PSYCHOLOGICAL OUTCOMES, WITH POTENTIAL FOR ALSO IMPROVING PHYSICAL SYMPTOMS. EVIDENCE IS INSUFFICIENT TO EVALUATE THE EFFICACY OF YOGA IN PEDIATRIC ONCOLOGY. WE DESCRIBE SUGGESTIONS FOR STRENGTHENING YOGA RESEARCH METHODOLOGY TO INFORM CLINICAL PRACTICE GUIDELINES.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
18 2023  39 SYSTEMATIC REVIEW OF YOGA FOR SYMPTOM MANAGEMENT DURING CONVENTIONAL TREATMENT OF BREAST CANCER PATIENTS. INTRODUCTION: BREAST CANCER IS ONE OF THE MOST COMMONLY DIAGNOSED CANCERS IN WOMEN IN THE US, AND ITS TREATMENTS HAVE SIGNIFICANT PHYSICAL AND PSYCHOLOGICAL SIDE EFFECTS AND LONG-TERM COMPLICATIONS CAUSING SIGNIFICANT MORBIDITY AND DECREASED QUALITY OF LIFE. INTEGRATIVE MEDICINE MODALITIES, SUCH AS YOGA, HAVE BEEN FOUND TO REDUCE SIDE EFFECTS OF CONVENTIONAL TREATMENTS WITHOUT INTERFERING WITH THE TREATMENT ITSELF AND IMPROVE QUALITY OF LIFE. IN THIS SYSTEMATIC REVIEW, WE SPECIFICALLY EXPLORED YOGA AS A POTENTIAL OPTION FOR SYMPTOMATIC MANAGEMENT IN PATIENTS UNDERGOING CONVENTIONAL BREAST CANCER TREATMENTS. METHODS: WE PERFORMED A LITERATURE SEARCH THAT WAS CONDUCTED TO INCLUDE THE DATABASES PUBMED, PSYCHINFO, COCHRANE LIBRARY, SCOPUS, AND CINAHL, RESULTING IN 28 RANDOMIZED CONTROLLED TRIAL (RCT) ARTICLES. WE REVIEW THE RESULTS OF THESE TRIALS REGARDING THE IMPACT OF YOGA IN THIS PATIENT POPULATION. RESULTS: OVERALL, THE MAJORITY OF THE RCT ARTICLES SHOWED SIGNIFICANT BENEFITS OF YOGA INTERVENTION IN VARIOUS ASPECTS OF QUALITY OF LIFE, FATIGUE, NAUSEA/VOMITING, SLEEP QUALITY, ANXIETY, DEPRESSION, AND DISTRESS. THERE ARE SEVERAL STUDIES THAT HAVE EXPLORED THE PHYSIOLOGICAL MECHANISM BEHIND THE EFFECTS OF YOGA AND FOUND THAT YOGA AFFECTS BOTH THE IMMUNE RESPONSE AND INFLAMMATION. DISCUSSION: THESE STUDIES REVEALED THAT YOGA HAS A POTENTIAL THERAPEUTIC ROLE IN THE SYMPTOMATIC MANAGEMENT OF BREAST CANCER PATIENTS, ENHANCING QUALITY OF LIFE DURING TREATMENT AS WELL AS IMPROVING ADHERENCE TO TREATMENT. FUTURE STUDIES WITH MORE DEFINED AND CONSISTENT METHODOLOGIES ARE NECESSARY TO FULLY UNDERSTAND THE POTENTIAL USE OF YOGA THERAPY IN PATIENTS WITH BREAST CANCER.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
19 2488  30 YOGA AS AN INTERVENTION FOR THE REDUCTION OF SYMPTOMS OF ANXIETY AND DEPRESSION IN CHILDREN AND ADOLESCENTS: A SYSTEMATIC REVIEW. PURPOSE: THE PURPOSE OF THIS REVIEW IS TO EVALUATE THE IMPLEMENTATION AND EFFECTIVENESS OF YOGA FOR THE REDUCTION OF SYMPTOMS OF ANXIETY AND DEPRESSION IN YOUTH. TO OUR KNOWLEDGE, THERE ARE NO SYSTEMATIC REVIEWS TO DATE LOOKING AT THE REDUCTION OF SYMPTOMS OF BOTH ANXIETY AND DEPRESSION. METHODS: NUMEROUS SCIENTIFIC DATABASES WERE SEARCHED UP TO NOVEMBER 2018 FOR EXPERIMENTAL STUDIES ASSESSING CHANGES IN SYMPTOMS OF ANXIETY AND/OR DEPRESSION IN YOUTHS FOLLOWING YOGA INTERVENTIONS. QUALITY AND LEVEL OF EVIDENCE WERE ASSESSED, AND INFORMATION WAS SYNTHESIZED ACROSS STUDIES. RESULTS: TWENTY-SEVEN STUDIES INVOLVING YOUTH WITH VARYING HEALTH STATUSES WERE REVIEWED. INTERVENTION CHARACTERISTICS VARIED GREATLY ACROSS STUDIES REVEALING MULTIPLE FACTORS THAT MAY IMPACT INTERVENTION EFFICACY, HOWEVER 70% OF THE STUDIES OVERALL SHOWED IMPROVEMENTS. FOR STUDIES ASSESSING ANXIETY AND DEPRESSION, 58% SHOWED REDUCTIONS IN BOTH SYMPTOMS, WHILE 25% SHOWED REDUCTIONS IN ANXIETY ONLY. ADDITIONALLY, 70% OF STUDIES ASSESSING ANXIETY ALONE SHOWED IMPROVEMENTS AND 40% OF STUDIES ONLY ASSESSING DEPRESSION SHOWED IMPROVEMENTS. CONCLUSION: THE STUDIES REVIEWED, WHILE OF WEAK TO MODERATE METHODOLOGICAL QUALITY, SHOWED THAT YOGA, DEFINED BY THE PRACTICE OF POSTURES, GENERALLY LEADS TO SOME REDUCTIONS IN ANXIETY AND DEPRESSION IN YOUTH REGARDLESS OF HEALTH STATUS AND INTERVENTION CHARACTERISTICS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
20  698  35 EFFECT OF HATHA YOGA ON ANXIETY: A META-ANALYSIS. OBJECTIVE: SOME EVIDENCE SUGGESTS THAT HATHA YOGA MIGHT BE AN EFFECTIVE PRACTICE TO REDUCE ANXIETY. TO EXAMINE THE EFFECT OF HATHA YOGA ON ANXIETY, WE CONDUCTED A META-ANALYSIS OF RELEVANT STUDIES EXTRACTED FROM PUBMED, PSYCINFO, THE COCHRANE LIBRARY, AND MANUAL SEARCHES. METHODS: THE SEARCH IDENTIFIED 17 STUDIES (11 WAITLIST CONTROLLED TRIALS) TOTALING 501 PARTICIPANTS WHO RECEIVED HATHA YOGA AND WHO REPORTED THEIR LEVELS OF ANXIETY BEFORE AND AFTER THE PRACTICE. WE ESTIMATED THE CONTROLLED AND WITHIN-GROUP RANDOM EFFECTS OF THE PRACTICE ON ANXIETY. RESULTS: THE PRE-POST WITHIN-GROUP AND CONTROLLED EFFECT SIZES WERE, HEDGES' G = 0.44 AND HEDGES' G = 0.61, RESPECTIVELY. TREATMENT EFFICACY WAS POSITIVELY ASSOCIATED WITH THE TOTAL NUMBER OF HOURS PRACTICED. PEOPLE WITH ELEVATED LEVELS OF ANXIETY BENEFITTED THE MOST. EFFECT SIZES WERE NOT MODERATED BY STUDY YEAR, GENDER, PRESENCE OF A MEDICAL DISORDER, OR AGE. ALTHOUGH THE QUALITY OF THE STUDIES WAS RELATIVELY LOW, THE RISK OF STUDY BIAS DID NOT MODERATE THE EFFECT. CONCLUSIONS: HATHA YOGA IS A PROMISING METHOD FOR TREATING ANXIETY. HOWEVER, MORE WELL-CONTROLLED STUDIES ARE NEEDED TO COMPARE THE EFFICACY OF HATHA YOGA WITH OTHER MORE ESTABLISHED TREATMENTS AND TO UNDERSTAND ITS MECHANISM. THIS ARTICLE IS PROTECTED BY COPYRIGHT. ALL RIGHTS RESERVED.	2016