1 2847 160 YOGA, MEDITATION AND MIND-BODY HEALTH: INCREASED BDNF, CORTISOL AWAKENING RESPONSE, AND ALTERED INFLAMMATORY MARKER EXPRESSION AFTER A 3-MONTH YOGA AND MEDITATION RETREAT. THIRTY-EIGHT INDIVIDUALS (MEAN AGE: 34.8 YEARS OLD) PARTICIPATING IN A 3-MONTH YOGA AND MEDITATION RETREAT WERE ASSESSED BEFORE AND AFTER THE INTERVENTION FOR PSYCHOMETRIC MEASURES, BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF), CIRCADIAN SALIVARY CORTISOL LEVELS, AND PRO- AND ANTI-INFLAMMATORY CYTOKINES. PARTICIPATION IN THE RETREAT WAS FOUND TO BE ASSOCIATED WITH DECREASES IN SELF-REPORTED ANXIETY AND DEPRESSION AS WELL AS INCREASES IN MINDFULNESS. AS HYPOTHESIZED, INCREASES IN THE PLASMA LEVELS OF BDNF AND INCREASES IN THE MAGNITUDE OF THE CORTISOL AWAKENING RESPONSE (CAR) WERE ALSO OBSERVED. THE NORMALIZED CHANGE IN BDNF LEVELS WAS INVERSELY CORRELATED WITH BSI-18 ANXIETY SCORES AT BOTH THE PRE-RETREAT (R = 0.40, P < 0.05) AND POST-RETREAT (R = 0.52, P < 0.005) SUCH THAT THOSE WITH GREATER ANXIETY SCORES TENDED TO EXHIBIT SMALLER PRE- TO POST-RETREAT INCREASES IN PLASMA BDNF LEVELS. IN LINE WITH A HYPOTHESIZED DECREASE IN INFLAMMATORY PROCESSES RESULTING FROM THE YOGA AND MEDITATION PRACTICES, WE FOUND THAT THE PLASMA LEVEL OF THE ANTI-INFLAMMATORY CYTOKINE INTERLEUKIN-10 WAS INCREASED AND THE PRO-INFLAMMATORY CYTOKINE INTERLEUKIN-12 WAS REDUCED AFTER THE RETREAT. CONTRARY TO OUR INITIAL HYPOTHESES, PLASMA LEVELS OF OTHER PRO-INFLAMMATORY CYTOKINES, INCLUDING INTERFERON GAMMA (IFN-GAMMA), TUMOR NECROSIS FACTOR (TNF-ALPHA), INTERLEUKIN-1BETA (IL-1BETA), INTERLEUKIN-6 (IL-6), AND INTERLEUKIN-8 (IL-8) WERE INCREASED AFTER THE RETREAT. GIVEN EVIDENCE FROM PREVIOUS STUDIES OF THE POSITIVE EFFECTS OF MEDITATIVE PRACTICES ON MENTAL FITNESS, AUTONOMIC HOMEOSTASIS AND INFLAMMATORY STATUS, WE HYPOTHESIZE THAT THESE FINDINGS ARE RELATED TO THE MEDITATIVE PRACTICES THROUGHOUT THE RETREAT; HOWEVER, SOME OF THE OBSERVED CHANGES MAY ALSO BE RELATED TO OTHER ASPECTS OF THE RETREAT SUCH AS PHYSICAL EXERCISE-RELATED COMPONENTS OF THE YOGA PRACTICE AND DIET. WE HYPOTHESIZE THAT THE PATTERNS OF CHANGE OBSERVED HERE REFLECT MIND-BODY INTEGRATION AND WELL-BEING. THE INCREASED BDNF LEVELS OBSERVED IS A POTENTIAL MEDIATOR BETWEEN MEDITATIVE PRACTICES AND BRAIN HEALTH, THE INCREASED CAR IS LIKELY A REFLECTION OF INCREASED DYNAMIC PHYSIOLOGICAL AROUSAL, AND THE RELATIONSHIP OF THE DUAL ENHANCEMENT OF PRO- AND ANTI-INFLAMMATORY CYTOKINE CHANGES TO HEALTHY IMMUNOLOGIC FUNCTIONING IS DISCUSSED.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
2 1424  34 IMPROVEMENT IN PHYSIOLOGICAL AND PSYCHOLOGICAL PARAMETERS AFTER 6 MONTHS OF YOGA PRACTICE. YOGA IS BELIEVED TO HAVE BENEFICIAL EFFECTS ON COGNITION, ATTENUATION OF EMOTIONAL INTENSITY AND STRESS REDUCTION. PREVIOUS STUDIES WERE MAINLY PERFORMED ON EASTERN EXPERIENCED PRACTITIONERS OR UNHEALTHY SUBJECTS UNDERGOING CONCOMITANT CONVENTIONAL THERAPIES. FURTHER INVESTIGATION IS NEEDED ON THE EFFECTS OF YOGA PER SE, AS WELL AS ITS POSSIBLE PREVENTIVE BENEFITS ON HEALTHY SUBJECTS. WE INVESTIGATED THE EFFECTS OF YOGA ON MEMORY AND PSYCHOPHYSIOLOGICAL PARAMETERS RELATED TO STRESS, COMPARING YOGA PRACTICE AND CONVENTIONAL PHYSICAL EXERCISES IN HEALTHY MEN (PREVIOUSLY YOGA-NAIVE). MEMORY TESTS, SALIVARY CORTISOL LEVELS AND STRESS, ANXIETY, AND DEPRESSION INVENTORIES WERE ASSESSED BEFORE AND AFTER 6 MONTHS OF PRACTICE. YOGA PRACTITIONERS SHOWED IMPROVEMENT OF THE MEMORY PERFORMANCE, AS WELL AS IMPROVEMENTS IN PSYCHOPHYSIOLOGICAL PARAMETERS. THE PRESENT RESULTS SUGGEST THAT REGULAR YOGA PRACTICE CAN IMPROVE ASPECTS OF COGNITION AND QUALITY OF LIFE FOR HEALTHY INDIVIDUALS. AN INDIRECT INFLUENCE OF EMOTIONAL STATE ON COGNITIVE IMPROVEMENT PROMOTED BY YOGA PRACTICE CAN BE PROPOSED.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
3  392  37 BENEFITS OF YOGA ON IL-6: FINDINGS FROM A RANDOMIZED CONTROLLED TRIAL OF YOGA FOR DEPRESSION. THE PRESENT RESEARCH SOUGHT TO EXAMINE WHETHER HATHA YOGA, IMPLEMENTED AS AN ADJUNCTIVE INTERVENTION FOR MAJOR DEPRESSION, INFLUENCES MARKERS OF INFLAMMATION. A SUBSET OF 84 PARTICIPANTS WHO WERE ENROLLED IN A RANDOMIZED CONTROLLED TRIAL (RCT) OF HATHA YOGA VS. HEALTH EDUCATION CONTROL PROVIDED BLOOD SAMPLES AT BASELINE (PRE-TREATMENT) AND AT 3-(DURING TREATMENT) AND 10-WEEK (END OF TREATMENT) FOLLOW-UP VISITS. TO BE ELIGIBLE FOR THE RCT, PARTICIPANTS MET CRITERIA FOR A CURRENT OR RECENT (PAST TWO YEARS) MAJOR DEPRESSIVE EPISODE, HAD CURRENT ELEVATED DEPRESSION SYMPTOMS, AND CURRENT ANTIDEPRESSANT MEDICATION USE. VENOUS BLOOD WAS DRAWN BETWEEN 2 AND 6 PM AND FOLLOWING AT LEAST ONE HOUR OF FASTING, AND INFLAMMATORY MARKERS (IL-6, CRP, AND TNF-ALPHA) WERE ASSAYED. EFFECTS OF PARTICIPATION IN YOGA RELATIVE TO HEALTH EDUCATION ON INFLAMMATORY MARKERS OVER TIME WERE EXAMINED WITH LATENT GROWTH ANALYSES. WE OBSERVED A SIGNIFICANT REDUCTION IN IL-6 CONCENTRATIONS IN THE YOGA TREATMENT GROUP RELATIVE TO THE HEALTH EDUCATION CONTROL GROUP AS DEMONSTRATED BY A NEGATIVE INTERACTION BETWEEN TREATMENT GROUP AND SLOPE OF IL-6. TNF-ALPHA AND CRP DID NOT EVIDENCE SIGNIFICANT INTERACTIONS OF TREATMENT GROUP BY MEAN SLOPE OR INTERCEPT. IN ADDITION TO THE BENEFITS OF HATHA YOGA AS AN ADJUNCTIVE INTERVENTION FOR INDIVIDUALS WHO HAVE SHOWN INADEQUATE RESPONSE TO ANTIDEPRESSANT MEDICATIONS, OUR FINDINGS POINT TO POSSIBLE BENEFITS OF YOGA ON IL-6 IN DEPRESSED POPULATIONS. FURTHER RESEARCH IS NEEDED TO EXPLORE THE EFFECTS OF HATHA YOGA ON IMMUNE FUNCTION OVER TIME.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
4  859  35 EFFECT OF YOGA PRACTICE ON LEVELS OF INFLAMMATORY MARKERS AFTER MODERATE AND STRENUOUS EXERCISE. BACKGROUND AND OBJECTIVES: TO EVALUATE THE EFFECT OF YOGA PRACTICE AND EXERCISE CHALLENGE ON TUMOUR NECROSIS FACTOR ALPHA (TNF-ALPHA), INTERLEUKIN-6 (IL-6) LEVELS AND LIPID PROFILE. MATERIALS AND METHODS: TWO HUNDRED AND EIGHTEEN SUBJECTS PARTICIPATED IN THE STUDY. ONE HUNDRED AND NINE VOLUNTEERS (51 MALES AND 58 FEMALES) IN THE AGE GROUP OF 20 TO 60 YEARS, WHO PRACTICED YOGA REGULARLY FOR OVER FIVE YEARS FOR A PERIOD OF ONE HOUR DAILY, PERFORMED A BOUT OF MODERATE EXERCISE AND A BOUT OF STRENUOUS EXERCISE AS PER STANDARDIZED SHUTTLE WALK TEST PROTOCOL. ANTHROPOMETRICALLY MATCHED, AGE MATCHED AND GENDER MATCHED SUBJECTS, WHO DID NOT PRACTICE YOGA (NON-YOGA GROUP) WERE CHOSEN AS CONTROLS (NON-YOGA, N=109). THE NON-YOGA GROUP ALSO PERFORMED SIMILAR EXERCISES. THE BLOOD SAMPLES OF BOTH THE GROUPS WERE COLLECTED BEFORE AND AFTER THE EXERCISES. TNF-ALPHA AND IL-6 WAS ANALYSED BEFORE AND AFTER THE EXERCISE BY SANDWICH ELISA (ENZYME LINKED IMMUNOSORBENT ASSAY). RESULTS: RESTING PLASMA TNF-ALPHA CONCENTRATION WAS SIGNIFICANTLY HIGHER IN NON-YOGA GROUP WHEN COMPARED TO YOGA GROUP (P<0.05). THERE WAS AN INCREASE IN TNF-ALPHA LEVELS IN BOTH THE GROUPS IN RESPONSE TO STRENUOUS EXERCISE. THERE WAS NO GENDER DIFFERENCE IN TNF-ALPHA AND IL-6 LEVELS BEFORE AND AFTER EXERCISE IN YOGA AND NON-YOGA GROUPS. CONCLUSION: REGULAR PRACTICE OF YOGA LOWERS BASAL TNF-ALPHA AND IL-6 LEVELS. IT ALSO REDUCES THE EXTENT OF INCREASE OF TNF-ALPHA AND IL-6 TO A PHYSICAL CHALLENGE OF MODERATE EXERCISE AND STRENUOUS EXERCISE. THERE IS NO SIGNIFICANT GENDER DIFFERENCE IN THE TNF-ALPHA AND IL-6 LEVELS. REGULAR PRACTICE OF YOGA CAN PROTECT THE INDIVIDUAL AGAINST INFLAMMATORY DISEASES BY FAVOURABLY ALTERING PRO-INFLAMMATORY CYTOKINE LEVELS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
5 1967  41 SERUM CORTISOL AND BDNF IN PATIENTS WITH MAJOR DEPRESSION-EFFECT OF YOGA. DEPRESSION IS ASSOCIATED WITH LOW SERUM BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) AND ELEVATED LEVELS OF SERUM CORTISOL. YOGA PRACTICES HAVE BEEN ASSOCIATED WITH ANTIDEPRESSANT EFFECTS, INCREASE IN SERUM BDNF, AND REDUCTION IN SERUM CORTISOL. THIS STUDY EXAMINED THE ASSOCIATION BETWEEN SERUM BDNF AND CORTISOL LEVELS IN DRUG-NAIVE PATIENTS WITH DEPRESSION TREATED WITH ANTIDEPRESSANTS, YOGA THERAPY, AND BOTH. FIFTY-FOUR DRUG-NAIVE CONSENTING ADULT OUTPATIENTS WITH MAJOR DEPRESSION (32 MALES) RECEIVED ANTIDEPRESSANTS ONLY (N = 16), YOGA THERAPY ONLY (N = 19), OR YOGA WITH ANTIDEPRESSANTS (N = 19). SERUM BDNF ANDCORTISOL LEVELS WERE OBTAINED BEFORE AND AFTER 3 MONTHS USING A SANDWICH ELISA METHOD. ONE-WAY ANOVA, CHI-SQUARE TEST, AND PEARSON'S CORRELATION TESTS WERE USED FOR ANALYSIS. THE GROUPS WERE COMPARABLE AT BASELINE ON MOST PARAMETERS. SIGNIFICANT IMPROVEMENT IN DEPRESSION SCORES AND SERUM BDNF LEVELS, AND REDUCTION IN SERUM CORTISOL IN THE YOGA GROUPS, HAVE BEEN DESCRIBED IN PREVIOUS REPORTS. A SIGNIFICANT NEGATIVE CORRELATION WAS OBSERVED BETWEEN CHANGE IN BDNF (PRE-POST) AND CORTISOL (PRE-POST) LEVELS IN THE YOGA-ONLY GROUP (R = -0.59, P = 0.008). IN CONCLUSION, YOGA MAY FACILITATE NEUROPLASTICITY THROUGH STRESS REDUCTION IN DEPRESSED PATIENTS. FURTHER STUDIES ARE NEEDED TO CONFIRM THE FINDINGS AND DELINEATE THE PATHWAYS FOR THESE EFFECTS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
6  716  31 EFFECT OF INTEGRATED YOGA PRACTICES ON IMMUNE RESPONSES IN EXAMINATION STRESS - A PRELIMINARY STUDY. BACKGROUND: STRESS IS OFTEN ASSOCIATED WITH AN INCREASED OCCURRENCE OF AUTONOMIC, CARDIOVASCULAR, AND IMMUNE SYSTEM PATHOLOGY. THIS STUDY WAS DONE TO EVALUATE THE IMPACT OF STRESS ON PSYCHOLOGICAL, PHYSIOLOGICAL PARAMETERS, AND IMMUNE SYSTEM DURING MEDICAL TERM -ACADEMIC EXAMINATION AND THE EFFECT OF YOGA PRACTICES ON THE SAME. MATERIALS AND METHODS: THE STUDY WAS CARRIED OUT ON SIXTY FIRST-YEAR MBBS STUDENTS RANDOMLY ASSIGNED TO YOGA GROUP AND CONTROL GROUP (30 EACH). THE YOGA GROUP UNDERWENT INTEGRATED YOGA PRACTICES FOR 35 MINUTES DAILY IN THE PRESENCE OF TRAINED YOGA TEACHER FOR 12 WEEKS. CONTROL GROUP DID NOT UNDERGO ANY KIND OF YOGA PRACTICE OR STRESS MANAGEMENT. PHYSIOLOGICAL PARAMETERS LIKE HEART RATE, RESPIRATORY RATE, AND BLOOD PRESSURE WERE MEASURED. GLOBAL ASSESSMENT OF RECENT STRESS SCALE AND SPIELBERGERS STATE ANXIETY SCORE WERE ASSESSED AT BASELINE AND DURING THE EXAMINATION. SERUM CORTISOL LEVELS, IL-4, AND IFN-GAMMA LEVELS WERE DETERMINED BY ENZYME-LINKED IMMUNOSORBENT ASSAY TECHNIQUE. RESULT: IN THE YOGA GROUP, NO SIGNIFICANT DIFFERENCE WAS OBSERVED IN PHYSIOLOGICAL PARAMETERS DURING THE EXAMINATION STRESS, WHEREAS IN THE CONTROL GROUP, A SIGNIFICANT INCREASE WAS OBSERVED. LIKEWISE, THE INDICATORS OF PSYCHOLOGICAL STRESS SHOWED HIGHLY SIGNIFICANT DIFFERENCE IN CONTROL GROUP COMPARED WITH SIGNIFICANT DIFFERENCE IN YOGA GROUP. DURING THE EXAMINATION, THE INCREASE IN SERUM CORTICAL AND DECREASE IN SERUM IFN-GAMMA IN YOGA GROUP WAS LESS SIGNIFICANT (P<0.01) THAN IN THE CONTROL GROUP (P<0.001). BOTH THE GROUPS DEMONSTRATED AN INCREASE IN SERUM IL-4 LEVELS, THE CHANGES BEING INSIGNIFICANT FOR THE DURATION OF THE STUDY. CONCLUSION: YOGA RESISTS THE AUTONOMIC CHANGES AND IMPAIRMENT OF CELLULAR IMMUNITY SEEN IN EXAMINATION STRESS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
7 1811  40 PROFILE OF MOOD STATES AND STRESS-RELATED BIOCHEMICAL INDICES IN LONG-TERM YOGA PRACTITIONERS. BACKGROUND: PREVIOUS STUDIES HAVE SHOWN THE SHORT-TERM OR INTERMEDIATE-TERM PRACTICE OF YOGA TO BE USEFUL FOR AMELIORATING SEVERAL MENTAL DISORDERS AND PSYCHOSOMATIC DISORDERS. HOWEVER, LITTLE IS KNOWN ABOUT THE LONG-TERM INFLUENCES OF YOGA ON THE MENTAL STATE OR STRESS-RELATED BIOCHEMICAL INDICES. IF YOGA TRAINING HAS A STRESS-REDUCTION EFFECT AND ALSO IMPROVES AN INDIVIDUAL'S MENTAL STATES FOR A LONG TIME, LONG-TERM YOGA PRACTITIONERS MAY HAVE A BETTER MENTAL STATE AND LOWER STRESS-RELATED BIOCHEMICAL INDICES IN COMPARISON TO NON-EXPERIENCED PARTICIPANTS. THIS STUDY SIMULTANEOUSLY EXAMINED THE DIFFERENCES IN MENTAL STATES AND URINARY STRESS-RELATED BIOCHEMICAL INDICES BETWEEN LONG-TERM YOGA PRACTITIONERS AND NON-EXPERIENCED PARTICIPANTS. METHODS: THE PARTICIPANTS WERE 38 HEALTHY FEMALES WITH MORE THAN 2 YEARS OF EXPERIENCE WITH YOGA (LONG-TERM YOGA GROUP) AND 37 AGE-MATCHED HEALTHY FEMALES WHO HAD NOT PARTICIPATED IN YOGA (CONTROL GROUP). THEIR MENTAL STATES WERE ASSESSED USING THE PROFILE OF MOOD STATES (POMS) QUESTIONNAIRE. THE LEVEL OF CORTISOL, 8-HYDROXYDEOXYGUANOSINE (8-OHDG) AND BIOPYRRIN IN URINE WERE USED AS STRESS-RELATED BIOCHEMICAL INDICES. RESULTS: THE AVERAGE SELF-RATED MENTAL DISTURBANCE, TENSION-ANXIETY, ANGER-HOSTILITY, AND FATIGUE SCORES OF THE LONG-TERM YOGA GROUP WERE LOWER THAN THOSE OF THE CONTROL GROUP. THERE WAS A TREND TOWARD A HIGHER VIGOR SCORE IN THE LONG-TERM YOGA GROUP THAN THAT IN THE CONTROL GROUP. THERE WERE NO SIGNIFICANT DIFFERENCES IN THE SCORES FOR DEPRESSION AND CONFUSION IN THE POMS BETWEEN THE TWO GROUPS. THE URINE 8-OHDG CONCENTRATION SHOWED A TREND TOWARD TO BEING LOWER IN THE LONG-TERM YOGA GROUP IN COMPARISON TO THE CONTROL GROUP. THERE WERE NO SIGNIFICANT DIFFERENCES IN THE LEVELS OF URINE BIOPYRRIN OR CORTISOL. CONCLUSIONS: THE PRESENT FINDINGS SUGGEST THAT LONG-TERM YOGA TRAINING CAN REDUCE THE SCORES RELATED TO MENTAL HEALTH INDICATORS SUCH AS SELF-RATED ANXIETY, ANGER, AND FATIGUE.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
8 1105  38 EFFECTS OF YOGA VERSUS WALKING ON MOOD, ANXIETY, AND BRAIN GABA LEVELS: A RANDOMIZED CONTROLLED MRS STUDY. OBJECTIVES: YOGA AND EXERCISE HAVE BENEFICIAL EFFECTS ON MOOD AND ANXIETY. GAMMA-AMINOBUTYRIC ACID (GABA)-ERGIC ACTIVITY IS REDUCED IN MOOD AND ANXIETY DISORDERS. THE PRACTICE OF YOGA POSTURES IS ASSOCIATED WITH INCREASED BRAIN GABA LEVELS. THIS STUDY ADDRESSES THE QUESTION OF WHETHER CHANGES IN MOOD, ANXIETY, AND GABA LEVELS ARE SPECIFIC TO YOGA OR RELATED TO PHYSICAL ACTIVITY. METHODS: HEALTHY SUBJECTS WITH NO SIGNIFICANT MEDICAL/PSYCHIATRIC DISORDERS WERE RANDOMIZED TO YOGA OR A METABOLICALLY MATCHED WALKING INTERVENTION FOR 60 MINUTES 3 TIMES A WEEK FOR 12 WEEKS. MOOD AND ANXIETY SCALES WERE TAKEN AT WEEKS 0, 4, 8, 12, AND BEFORE EACH MAGNETIC RESONANCE SPECTROSCOPY SCAN. SCAN 1 WAS AT BASELINE. SCAN 2, OBTAINED AFTER THE 12-WEEK INTERVENTION, WAS FOLLOWED BY A 60-MINUTE YOGA OR WALKING INTERVENTION, WHICH WAS IMMEDIATELY FOLLOWED BY SCAN 3. RESULTS: THE YOGA SUBJECTS (N = 19) REPORTED GREATER IMPROVEMENT IN MOOD AND GREATER DECREASES IN ANXIETY THAN THE WALKING GROUP (N = 15). THERE WERE POSITIVE CORRELATIONS BETWEEN IMPROVED MOOD AND DECREASED ANXIETY AND THALAMIC GABA LEVELS. THE YOGA GROUP HAD POSITIVE CORRELATIONS BETWEEN CHANGES IN MOOD SCALES AND CHANGES IN GABA LEVELS. CONCLUSIONS: THE 12-WEEK YOGA INTERVENTION WAS ASSOCIATED WITH GREATER IMPROVEMENTS IN MOOD AND ANXIETY THAN A METABOLICALLY MATCHED WALKING EXERCISE. THIS IS THE FIRST STUDY TO DEMONSTRATE THAT INCREASED THALAMIC GABA LEVELS ARE ASSOCIATED WITH IMPROVED MOOD AND DECREASED ANXIETY. IT IS ALSO THE FIRST TIME THAT A BEHAVIORAL INTERVENTION (I.E., YOGA POSTURES) HAS BEEN ASSOCIATED WITH A POSITIVE CORRELATION BETWEEN ACUTE INCREASES IN THALAMIC GABA LEVELS AND IMPROVEMENTS IN MOOD AND ANXIETY SCALES. GIVEN THAT PHARMACOLOGIC AGENTS THAT INCREASE THE ACTIVITY OF THE GABA SYSTEM ARE PRESCRIBED TO IMPROVE MOOD AND DECREASE ANXIETY, THE REPORTED CORRELATIONS ARE IN THE EXPECTED DIRECTION. THE POSSIBLE ROLE OF GABA IN MEDIATING THE BENEFICIAL EFFECTS OF YOGA ON MOOD AND ANXIETY WARRANTS FURTHER STUDY.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
9  569  21 DECREASE IN SERUM CORTISOL DURING YOGA EXERCISE IS CORRELATED WITH ALPHA WAVE ACTIVATION. WE EXAMINED CHANGES IN BRAIN WAVES AND BLOOD LEVELS OF SERUM CORTISOL DURING YOGA EXERCISE IN 7 YOGA INSTRUCTORS AND FOUND THAT ALPHA WAVES INCREASED AND SERUM CORTISOL DECREASED. THESE TWO MEASURES WERE NEGATIVELY CORRELATED (R = -.83). COMPARISON WITH A CONTROL GROUP OF NONPRACTITIONERS IS DESIRABLE.	2000	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
10  835  38 EFFECT OF YOGA ON PAIN, BRAIN-DERIVED NEUROTROPHIC FACTOR, AND SEROTONIN IN PREMENOPAUSAL WOMEN WITH CHRONIC LOW BACK PAIN. BACKGROUND. SEROTONIN AND BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) ARE KNOWN TO BE MODULATORS OF NOCICEPTION. HOWEVER, PAIN-RELATED CONNECTION BETWEEN YOGA AND THOSE NEUROMODULATORS HAS NOT BEEN INVESTIGATED. THEREFORE, WE AIMED TO EVALUATE THE EFFECT OF YOGA ON PAIN, BDNF, AND SEROTONIN. METHODS. PREMENOPAUSAL WOMEN WITH CHRONIC LOW BACK PAIN PRACTICED YOGA THREE TIMES A WEEK FOR 12 WEEKS. AT BASELINE AND AFTER 12 WEEKS, BACK PAIN INTENSITY WAS MEASURED USING VISUAL ANALOGUE SCALE (VAS), AND SERUM BDNF AND SEROTONIN LEVELS WERE EVALUATED. ADDITIONALLY, BACK FLEXIBILITY AND LEVEL OF DEPRESSION WERE ASSESSED. RESULTS. AFTER 12-WEEK YOGA, VAS DECREASED IN THE YOGA GROUP (P < 0.001), WHEREAS IT INCREASED (P < 0.05) IN THE CONTROL GROUP. BACK FLEXIBILITY WAS IMPROVED IN THE YOGA GROUP (P < 0.01). SERUM BDNF INCREASED IN THE YOGA GROUP (P < 0.01), WHEREAS IT TENDED TO DECREASE IN THE CONTROL GROUP (P = 0.05). SERUM SEROTONIN MAINTAINED IN THE YOGA GROUP, WHILE IT REDUCED (P < 0.01) IN THE CONTROL GROUP. THE DEPRESSION LEVEL MAINTAINED IN THE YOGA GROUP, WHEREAS IT TENDED TO INCREASE IN THE CONTROL GROUP (P = 0.07). CONCLUSIONS. WE PROPOSE THAT BDNF MAY BE ONE OF THE KEY FACTORS MEDIATING BENEFICIAL EFFECTS OF YOGA ON CHRONIC LOW BACK PAIN.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
11  209  40 A SINGLE SESSION OF HATHA YOGA IMPROVES STRESS REACTIVITY AND RECOVERY AFTER AN ACUTE PSYCHOLOGICAL STRESS TASK-A COUNTERBALANCED, RANDOMIZED-CROSSOVER TRIAL IN HEALTHY INDIVIDUALS. OBJECTIVES: YOGA IS PROMOTED AS AN ANTI-STRESS ACTIVITY, HOWEVER, LITTLE IS KNOWN ABOUT THE MECHANISMS THROUGH WHICH IT ACTS. THE PRESENT STUDY INVESTIGATED THE ACUTE EFFECTS OF A HATHA YOGA SESSION, DISPLAYED ON A VIDEO, ON THE RESPONSE TO AND RECOVERY FROM AN ACUTE PSYCHOLOGICAL STRESSOR. METHODS: TWENTY-FOUR HEALTHY YOUNG ADULTS TOOK PART IN A COUNTERBALANCED, RANDOMIZED-CROSSOVER TRIAL, WITH A YOGA AND A CONTROL CONDITION (WATCHING TV). PARTICIPANTS ATTENDED THE LABORATORY IN THE AFTERNOON ON TWO DAYS AND EACH SESSION COMPRISED A BASELINE, CONTROL OR YOGA TASK, STRESS TASK AND RECOVERY. BLOOD PRESSURE (BP), HEART RATE (HR) AND SALIVARY CORTISOL RESPONSES WERE MEASURED. STATE COGNITIVE- AND SOMATIC-ANXIETY ALONG WITH SELF-CONFIDENCE WERE ASSESSED BEFORE AND AFTER THE STRESSOR. RESULTS: ALTHOUGH NO DIFFERENCE IN THE BP OR HR RESPONSES TO STRESS WERE FOUND BETWEEN CONDITIONS, SYSTOLIC BP (P=0.047) AND DIASTOLIC BP (P=0.018) RECOVERY FROM STRESS WERE SIGNIFICANTLY ACCELERATED AND SALIVARY CORTISOL REACTIVITY WAS SIGNIFICANTLY LOWER (P=0.01) IN THE YOGA CONDITION. A YOGA SESSION ALSO INCREASED SELF-CONFIDENCE (P=0.006) IN PREPARATION FOR THE TASK AND AFTER COMPLETION. MOREOVER, SELF-CONFIDENCE REPORTED AFTER THE STRESS TASK WAS CONSIDERED DEBILITATIVE TOWARDS PERFORMANCE IN THE CONTROL CONDITION, BUT REMAINED FACILITATIVE IN THE YOGA CONDITION. CONCLUSION: OUR RESULTS SHOW THAT A SINGLE VIDEO-INSTRUCTED SESSION OF HATHA YOGA WAS ABLE TO IMPROVE STRESS REACTIVITY AND RECOVERY FROM AN ACUTE STRESS TASK IN HEALTHY INDIVIDUALS. THESE POSITIVE PRELIMINARY FINDINGS ENCOURAGE FURTHER INVESTIGATION IN AT-RISK POPULATIONS IN WHICH THE MAGNITUDE OF EFFECTS MAY BE GREATER, AND SUPPORT THE USE OF YOGA FOR STRESS REACTIVITY AND RECOVERY.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
12 1707  27 PATTERNS OF YOGA PRACTICE AND PHYSICAL ACTIVITY FOLLOWING A YOGA INTERVENTION FOR ADULTS WITH OR AT RISK FOR TYPE 2 DIABETES. BACKGROUND: THE CURRENT STUDY DESCRIBED PATTERNS OF YOGA PRACTICE AND EXAMINED DIFFERENCES IN PHYSICAL ACTIVITY OVER TIME BETWEEN INDIVIDUALS WITH OR AT RISK FOR TYPE 2 DIABETES WHO COMPLETED AN 8-WEEK YOGA INTERVENTION COMPARED WITH CONTROLS. METHODS: A LONGITUDINAL COMPARATIVE DESIGN MEASURED THE EFFECT OF A YOGA INTERVENTION ON YOGA PRACTICE AND PHYSICAL ACTIVITY, USING DATA AT BASELINE AND POSTINTERVENTION MONTHS 3, 6, AND 15. RESULTS: DISPARATE PATTERNS OF YOGA PRACTICE OCCURRED BETWEEN INTERVENTION AND CONTROL PARTICIPANTS OVER TIME, BUT THE SUBJECTIVE DEFINITION OF YOGA PRACTICE LIMITS INTERPRETATION. MULTILEVEL MODEL ESTIMATES INDICATED THAT TREATMENT GROUP DID NOT HAVE A SIGNIFICANT INFLUENCE IN THE RATE OF CHANGE IN PHYSICAL ACTIVITY OVER THE STUDY PERIOD. WHILE AGE AND EDUCATION WERE NOT SIGNIFICANT INDIVIDUAL PREDICTORS, THE INCLUSION OF THESE VARIABLES IN THE MODEL DID IMPROVE FIT. CONCLUSIONS: FINDINGS INDICATE THAT AN 8-WEEK YOGA INTERVENTION HAD LITTLE EFFECT ON PHYSICAL ACTIVITY OVER TIME. FURTHER RESEARCH IS NECESSARY TO EXPLORE THE INFLUENCE OF YOGA ON BEHAVIORAL HEALTH OUTCOMES AMONG INDIVIDUALS WITH OR AT RISK FOR TYPE 2 DIABETES.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
13  784  29 EFFECT OF YOGA BASED LIFESTYLE INTERVENTION ON SUBJECTIVE WELL-BEING. YOGA IS ASSUMING IMPORTANCE IN IMPROVING MENTAL HEALTH AND QUALITY OF LIFE IN THE TREATMENT OF A NUMBER OF PSYCHIATRIC AND PSYCHOSOMATIC DISORDERS. THE PRESENT STUDY WAS A PROSPECTIVE CONTROLLED STUDY TO EXPLORE THE SHORT-TERM IMPACT OF A COMPREHENSIVE BUT BRIEF LIFESTYLE INTERVENTION, BASED ON YOGA, ON SUBJECTIVE WELL BEING LEVELS IN NORMAL AND DISEASED SUBJECTS. NORMAL HEALTHY INDIVIDUALS AND SUBJECTS HAVING HYPERTENSION, CORONARY ARTERY DISEASE, DIABETES MELLITUS OR A VARIETY OF OTHER ILLNESSES WERE INCLUDED IN THE STUDY. THE OUTCOME MEASURES WERE 'SUBJECTIVE WELL BEING INVENTORY' (SUBI) SCORES, TAKEN ON THE FIRST AND LAST DAY OF THE COURSE. THE INVENTORY CONSISTS OF QUESTIONS RELATED TO ONE'S FEELINGS AND ATTITUDE ABOUT VARIOUS AREAS OF LIFE, SUCH AS HAPPINESS, ACHIEVEMENT AND INTERPERSONAL RELATIONSHIP. THERE WAS SIGNIFICANT IMPROVEMENT IN THE SUBJECTIVE WELL BEING SCORES OF THE 77 SUBJECTS WITHIN A PERIOD OF 10 DAYS AS COMPARED TO CONTROLS. THESE OBSERVATIONS SUGGEST THAT A SHORT LIFESTYLE MODIFICATION AND STRESS MANAGEMENT EDUCATIONAL PROGRAM LEADS TO REMARKABLE IMPROVEMENT IN THE SUBJECTIVE WELL BEING SCORES OF THE SUBJECTS AND CAN THEREFORE MAKE AN APPRECIABLE CONTRIBUTION TO PRIMARY PREVENTION AS WELL AS MANAGEMENT OF LIFESTYLE DISEASES.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
14 2149  26 THE EFFECTS OF POWER AND STRETCH YOGA ON AFFECT AND SALIVARY CORTISOL IN WOMEN. YOGA PRACTICE IS KNOWN TO IMPROVE WELL-BEING AND DECREASE STRESS. HOWEVER, ACUTE YOGA IS UNDERSTUDIED. THIS STUDY INVESTIGATED THE EFFECTS OF TWO DIFFERENT TYPES OF YOGA ON AFFECT AND SALIVARY CORTISOL LEVELS IN COLLEGE WOMEN. THIRTY-THREE WOMEN AGED 18-30 YEARS EACH COMPLETED 1-HOUR SESSIONS OF POWER YOGA AND STRETCH YOGA. MEASURES OF AFFECT AND SALIVARY CORTISOL WERE ASSESSED BEFORE, DURING, AND AFTER EACH SESSION. PARTICIPANTS PERCEIVED POWER YOGA TO BE MORE PLEASURABLE AND ENERGIZING. SALIVARY CORTISOL SIGNIFICANTLY DECREASED AFTER BOTH YOGA SESSIONS. THUS, EVEN ONE SESSION OF YOGA MAY BE EFFECTIVE IN IMPROVING AFFECT AND DECREASING STRESS IN COLLEGE WOMEN.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
15  845  29 EFFECT OF YOGA ON PULSE RATE AND BLOOD PRESSURE AMONG WOMEN. OBJECTIVES: CHANGE IN THE PAST FEW DECADES IN HUMAN LIFE STYLE, NOWADAYS INTERNATIONAL HEALTH ORGANIZATIONS, I.E., WORLD HEALTH ORGANIZATION ARE ALSO FOCUSING ON PREVENTION ALONG WITH TREATMENT ASPECT OF CHRONIC ILLNESS. RESEARCHES FOCUS THAT WOMEN OF AGE GROUP 30-45 YEARS ARE AT INCREASED RISK FOR HYPERTENSION AND HEART DISEASE DUE TO INCREASED WEIGHT. YOGA IS AN EFFECTIVE METHOD TO CONTROL OUR PHYSIOLOGICAL VARIABLES LIKE BLOOD PRESSURE (BP), PULSE, ETC. THE MAIN AIM OF THIS STUDY WAS TO IDENTIFY THE EFFECTS OF YOGA ON PHYSIOLOGICAL VARIABLES. METHODS: THE STUDY WAS AN EXPERIMENTAL STUDY WITH TWO GROUP, PRETEST AND POSTTEST CONTROL GROUP, DESIGN, WHICH WAS CONDUCTED ON 40 FEMALE PARTICIPANTS. PRANAYAMA AND MEDITATION FOR A PERIOD OF 6 WEEKS WAS DONE BY THESE WOMEN. RESULTS: YOGA THERAPY SIGNIFICANTLY REDUCED THE BP (0.000*) AND PULSE RATE (0.000*) OF WOMEN, WHICH WAS ALSO STATISTICALLY PROVED. CONCLUSIONS: YOGA THERAPY CAN BE AN EFFECTIVE METHOD TO CONTROL BP AND PULSE RATE OF PATIENTS WITH CHRONIC DISEASES.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
16 1789  42 PRELIMINARY INDICATIONS OF THE EFFECT OF A BRIEF YOGA INTERVENTION ON MARKERS OF INFLAMMATION AND DNA METHYLATION IN CHRONICALLY STRESSED WOMEN. YOGA IS ASSOCIATED WITH REDUCED STRESS AND INCREASED WELL-BEING, ALTHOUGH THE MOLECULAR BASIS FOR THESE BENEFITS IS NOT CLEAR. MOUNTING EVIDENCE IMPLICATES THE IMMUNE RESPONSE, WITH CURRENT STUDIES FOCUSED ON PROTEIN IMMUNE MARKERS (SUCH AS CYTOKINES) IN CLINICAL POPULATIONS. TO EXPLORE THE MOLECULAR IMPACT, THIS PILOT STUDY USES A SUBSAMPLE (N=28) FROM A RANDOMISED WAITLIST CONTROL TRIAL INVESTIGATING THE IMPACT OF AN 8-WEEK YOGA INTERVENTION IN A COMMUNITY POPULATION OF WOMEN REPORTING PSYCHOLOGICAL DISTRESS (N=116). WE MEASURED INTERLEUKIN-6 (IL-6), TUMOUR NECROSIS FACTOR (TNF) AND C-REACTIVE PROTEIN (CRP) PROTEIN LEVELS, AND THE DNA METHYLATION OF THESE GENES AND THE GLOBAL INDICATOR, LINE-1. CORRELATIONS BETWEEN THESE AND PSYCHOLOGICAL VARIABLES WERE EXPLORED, IDENTIFYING MODERATE CORRELATIONS WITH CRP PROTEIN LEVELS, AND METHYLATION OF IL-6, CRP AND LINE-1. MANY CYTOKINE SAMPLES WERE BELOW DETECTION, HOWEVER A MANN-WHITNEY U DEMONSTRATED A TREND OF MODERATE BETWEEN-GROUP EFFECT FOR ELEVATED IL-6 IN THE YOGA GROUP. METHYLATION ANALYSES APPLIED CROSS-SECTIONAL AND NON-CONTROLLED LONGITUDINAL ANALYSES. WAIST-TO-HEIGHT RATIO AND AGE WERE COVARIED. WE DEMONSTRATED REDUCED METHYLATION OF THE TNF REGION IN THE YOGA GROUP RELATIVE TO THE WAITLIST CONTROL GROUP. NO OTHER GENES DEMONSTRATED A SIGNIFICANT DIFFERENCE. LONGITUDINAL ANALYSIS FURTHER SUPPORTED THESE RESULTS. THIS STUDY IS ONE OF THE FIRST TO EXPLORE YOGA AND IMMUNOLOGICAL MARKERS IN A NON-CLINICAL POPULATION, AND IS THE FIRST STUDY TO EXPLORE DNA METHYLATION. THESE FINDINGS INDICATE THAT FURTHER RESEARCH INTO MOLECULAR IMPACT OF YOGA ON MARKERS OF IMMUNE FUNCTION IS WARRANTED, WITH LARGER STUDIES REQUIRED.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
17 2516  27 YOGA CLINICAL RESEARCH REVIEW. IN THIS PAPER RECENT RESEARCH IS REVIEWED ON THE EFFECTS OF YOGA POSES ON PSYCHOLOGICAL CONDITIONS INCLUDING ANXIETY AND DEPRESSION, ON PAIN SYNDROMES, CARDIOVASCULAR, AUTOIMMUNE AND IMMUNE CONDITIONS AND ON PREGNANCY. FURTHER, THE PHYSIOLOGICAL EFFECTS OF YOGA INCLUDING DECREASED HEARTRATE AND BLOOD PRESSURE AND THE PHYSICAL EFFECTS INCLUDING WEIGHT LOSS AND INCREASED MUSCLE STRENGTH ARE REVIEWED. FINALLY, POTENTIAL UNDERLYING MECHANISMS ARE PROPOSED INCLUDING THE STIMULATION OF PRESSURE RECEPTORS LEADING TO ENHANCED VAGAL ACTIVITY AND REDUCED CORTISOL. THE REDUCTION IN CORTISOL, IN TURN, MAY CONTRIBUTE TO POSITIVE EFFECTS SUCH AS ENHANCED IMMUNE FUNCTION AND A LOWER PREMATURITY RATE.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
18 2000  26 STRESS MANAGEMENT: A RANDOMIZED STUDY OF COGNITIVE BEHAVIOURAL THERAPY AND YOGA. IN THIS STUDY, A STRESS MANAGEMENT PROGRAM BASED ON COGNITIVE BEHAVIOURAL THERAPY PRINCIPLES WAS COMPARED WITH A KUNDALINIYOGA PROGRAM. A STUDY SAMPLE OF 26 WOMEN AND 7 MEN FROM A LARGE SWEDISH COMPANY WERE DIVIDED RANDOMLY INTO 2 GROUPS FOR EACH OF THE DIFFERENT FORMS OF INTERVENTION; A TOTAL OF 4 GROUPS. THE GROUPS WERE INSTRUCTED BY TRAINED GROUP LEADERS AND 10 SESSIONS WERE HELD WITH EACH OF GROUPS, OVER A PERIOD OF 4 MONTHS. PSYCHOLOGICAL (SELF-RATED STRESS AND STRESS BEHAVIOUR, ANGER, EXHAUSTION, QUALITY OF LIFE) AND PHYSIOLOGICAL (BLOOD PRESSURE, HEART RATE, URINARY CATECHOLAMINES, SALIVARY CORTISOL) MEASUREMENTS OBTAINED BEFORE AND AFTER TREATMENT SHOWED SIGNIFICANT IMPROVEMENTS ON MOST OF THE VARIABLES IN BOTH GROUPS AS WELL AS MEDIUM-TO-HIGH EFFECT SIZES. HOWEVER, NO SIGNIFICANT DIFFERENCE WAS FOUND BETWEEN THE 2 PROGRAMS. THE RESULTS INDICATE THAT BOTH COGNITIVE BEHAVIOUR THERAPY AND YOGA ARE PROMISING STRESS MANAGEMENT TECHNIQUES.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
19  341  48 ARTERIAL BLOOD PRESSURE AND CARDIOVASCULAR RESPONSES TO YOGA PRACTICE. CONTEXT: YOGA IS QUALITATIVELY DIFFERENT FROM ANY OTHER MODE OF PHYSICAL ACTIVITY IN THAT IT CONSISTS OF A UNIQUE COMBINATION OF ISOMETRIC MUSCULAR CONTRACTIONS, STRETCHING EXERCISES, RELAXATION TECHNIQUES, AND BREATHING EXERCISES. IN PARTICULAR, YOGA POSTURES CONSIST OF SYSTEMIC ISOMETRIC CONTRACTIONS THAT ARE KNOWN TO ELICIT MARKED INCREASES IN MEAN BLOOD PRESSURE THAT ARE NOT OBSERVED DURING DYNAMIC EXERCISE. STRETCHING CAN ALSO INDUCE INCREASES IN BLOOD PRESSURE AND SYMPATHETIC NERVE ACTIVITY IN THE MUSCLES. CURRENTLY, NOT MUCH IS KNOWN ABOUT CHANGES IN BLOOD PRESSURE AND OTHER CARDIOVASCULAR RESPONSES TO YOGA PRACTICE. OBJECTIVE: THE STUDY INTENDED TO DETERMINE THE ACUTE EFFECTS OF ONE SESSION OF HATHA YOGA PRACTICE ON BLOOD PRESSURE AND OTHER CARDIOVASCULAR RESPONSES. TO GAIN INSIGHT INTO THE LONG-TERM EFFECTS OF YOGA PRACTICE, BOTH NOVICE (N = 19) AND ADVANCED (N = 18) YOGA PRACTITIONERS WERE STUDIED. DESIGN: THE TWO GROUPS WERE MATCHED FOR AGE, GENDER, BMI, AND BLOOD PRESSURE. SETTING: THE SETTING WAS A RESEARCH LABORATORY AT A UNIVERSITY. PARTICIPANTS: THIRTY-SIX APPARENTLY HEALTHY, NONOBESE, SEDENTARY, OR RECREATIONALLY ACTIVE INDIVIDUALS FROM THE COMMUNITY PARTICIPATED IN THE STUDY. INTERVENTION THE INTERVENTION COMPRISED ONE SESSION OF YOGA PRACTICE, IN WHICH PARTICIPANTS FOLLOWED A CUSTOM MADE INSTRUCTIONAL VIDEO PROVIDING A YOGA ROUTINE THAT CONSISTED OF A SERIES OF 23 HATHA-BASED YOGA POSTURES. OUTCOME MEASURES: PRIOR TO ARRIVING AT THE LABORATORY, EACH PARTICIPANT COMPLETED A RESEARCH HEALTH QUESTIONNAIRE, A TRAINING-STATUS QUESTIONNAIRE, AND A YOGA-EXPERIENCE QUESTIONNAIRE. PRIOR TO THE YOGA PRACTICE, EACH PARTICIPANT'S HEIGHT, BODY FAT PERCENTAGE, TRUNK OR LUMBAR FLEXIBILITY, AND ARTERIAL STIFFNESS AS ASSESSED BY CAROTID FEMORAL PULSE WAVE VELOCITY (CFPWV) WERE MEASURED. FOR EACH POSTURE DURING THE YOGA PRACTICE, THE STUDY CONTINUOUSLY MEASURED SYSTOLIC, MEAN, AND DIASTOLIC BLOOD PRESSURES, HEART RATE, STROKE VOLUME, AND CARDIAC OUTPUT. RESULTS: SYSTOLIC, MEAN, AND DIASTOLIC BLOOD PRESSURES INCREASED SIGNIFICANTLY DURING THE YOGA PRACTICE. THE MAGNITUDE OF THESE INCREASES IN BLOOD PRESSURE WAS GREATEST WITH STANDING POSTURES. HEART RATE AND CARDIAC OUTPUT INCREASED SIGNIFICANTLY DURING YOGA PRACTICE, ESPECIALLY WITH STANDING POSTURES. OVERALL, NO DIFFERENCES EXISTED IN CARDIOVASCULAR RESPONSES BETWEEN THE NOVICE AND ADVANCED PRACTITIONERS THROUGHOUT THE YOGA TESTING SESSION; CFPWV VELOCITY WAS SIGNIFICANTLY AND INVERSELY ASSOCIATED WITH LUMBAR FLEXION BUT NOT WITH SIT-AND-REACH TEST SCORES. CONCLUSIONS: THE RESEARCH TEAM CONCLUDED THAT A VARIETY OF HATHA YOGA POSTURES, ESPECIALLY STANDING POSTURES, EVOKED SIGNIFICANT INCREASES IN BLOOD PRESSURE. THE ELEVATION IN BLOOD PRESSURE DUE TO YOGA PRACTICE WAS ASSOCIATED WITH INCREASES IN CARDIAC OUTPUT AND HEART RATE, WHICH ARE RESPONSES SIMILAR TO THOSE OBSERVED IN ISOMETRIC EXERCISE. THE LACK OF OBVIOUS DIFFERENCES IN BLOOD PRESSURE AND OTHER CARDIOVASCULAR RESPONSES BETWEEN NOVICE AND ADVANCED YOGA PRACTITIONERS SUGGESTS THAT LONG-TERM YOGA PRACTICE DOES NOT ATTENUATE ACUTE YOGA RESPONSES.	2013	

20 2001  38 STRESS, INFLAMMATION, AND YOGA PRACTICE. OBJECTIVE: TO ADDRESS THE MECHANISMS UNDERLYING HATHA YOGA'S POTENTIAL STRESS-REDUCTION BENEFITS, WE COMPARED INFLAMMATORY AND ENDOCRINE RESPONSES OF NOVICE AND EXPERT YOGA PRACTITIONERS BEFORE, DURING, AND AFTER A RESTORATIVE HATHA YOGA SESSION, AS WELL AS IN TWO CONTROL CONDITIONS. STRESSORS BEFORE EACH OF THE THREE CONDITIONS PROVIDED DATA ON THE EXTENT TO WHICH YOGA SPEEDED AN INDIVIDUAL'S PHYSIOLOGICAL RECOVERY. METHODS: A TOTAL OF 50 HEALTHY WOMEN (MEAN AGE, 41.32 YEARS; RANGE, 30-65 YEARS), 25 NOVICES AND 25 EXPERTS, WERE EXPOSED TO EACH OF THE CONDITIONS (YOGA, MOVEMENT CONTROL, AND PASSIVE-VIDEO CONTROL) DURING THREE SEPARATE VISITS. RESULTS: THE YOGA SESSION BOOSTED PARTICIPANTS' POSITIVE AFFECT COMPARED WITH THE CONTROL CONDITIONS, BUT NO OVERALL DIFFERENCES IN INFLAMMATORY OR ENDOCRINE RESPONSES WERE UNIQUE TO THE YOGA SESSION. IMPORTANTLY, EVEN THOUGH NOVICES AND EXPERTS DID NOT DIFFER ON KEY DIMENSIONS, INCLUDING AGE, ABDOMINAL ADIPOSITY, AND CARDIORESPIRATORY FITNESS, NOVICES' SERUM INTERLEUKIN (IL)-6 LEVELS WERE 41% HIGHER THAN THOSE OF EXPERTS ACROSS SESSIONS, AND THE ODDS OF A NOVICE HAVING DETECTABLE C-REACTIVE PROTEIN (CRP) WERE 4.75 TIMES AS HIGH AS THAT OF AN EXPERT. DIFFERENCES IN STRESS RESPONSES BETWEEN EXPERTS AND NOVICES PROVIDED ONE PLAUSIBLE MECHANISM FOR THEIR DIVERGENT SERUM IL-6 DATA; EXPERTS PRODUCED LESS LIPOPOLYSACCHARIDE-STIMULATED IL-6 IN RESPONSE TO THE STRESSOR THAN NOVICES, AND IL-6 PROMOTES CRP PRODUCTION. CONCLUSION: THE ABILITY TO MINIMIZE INFLAMMATORY RESPONSES TO STRESSFUL ENCOUNTERS INFLUENCES THE BURDEN THAT STRESSORS PLACE ON AN INDIVIDUAL. IF YOGA DAMPENS OR LIMITS STRESS-RELATED CHANGES, THEN REGULAR PRACTICE COULD HAVE SUBSTANTIAL HEALTH BENEFITS.	2010