1 2761 165 YOGA PREVENTS GRAY MATTER ATROPHY IN WOMEN AT RISK FOR ALZHEIMER'S DISEASE: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: FEMALE SEX, SUBJECTIVE COGNITIVE DECLINE (SCD), AND CARDIOVASCULAR RISK FACTORS (CVRFS) ARE KNOWN RISK FACTORS FOR DEVELOPING ALZHEIMER'S DISEASE (AD). WE PREVIOUSLY DEMONSTRATED THAT YOGA IMPROVED DEPRESSION, RESILIENCE, MEMORY AND EXECUTIVE FUNCTIONS, INCREASED HIPPOCAMPAL CHOLINE CONCENTRATIONS, AND MODULATED BRAIN CONNECTIVITY IN OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENT. OBJECTIVE: IN THIS STUDY (NCT03503669), WE INVESTIGATED BRAIN GRAY MATTER VOLUME (GMV) CHANGES IN OLDER WOMEN WITH SCD AND CVRFS FOLLOWING THREE MONTHS OF YOGA COMPARED TO MEMORY ENHANCEMENT TRAINING (MET). METHODS: ELEVEN WOMEN (MEAN AGE = 61.45, SD = 6.58) WITH CVRF AND SCD COMPLETED TWELVE WEEKS OF KUNDALINI YOGA AND KIRTAN KRIYA (KY + KK) WHILE ELEVEN WOMEN (MEAN AGE = 64.55, SD = 6.41) UNDERWENT MET. ANXIETY, RESILIENCE, STRESS, AND DEPRESSION WERE ASSESSED AT BASELINE AND 12 WEEKS, AS WERE T1-WEIGHTED MRI SCANS (SIEMENS 3T PRISMA SCANNER). WE USED FREESURFER 6.0 AND TESTED GROUP DIFFERENCES IN GMV CHANGE, APPLYING MONTE-CARLO SIMULATIONS WITH ALPHA = 0.05. REGION-OF-INTEREST ANALYSIS WAS PERFORMED FOR HIPPOCAMPUS AND AMYGDALA. RESULTS: COMPARED TO KY + KK, MET SHOWED REDUCTIONS IN GMV IN LEFT PREFRONTAL, PRE- AND POST-CENTRAL, SUPRAMARGINAL, SUPERIOR TEMPORAL AND PERICALCARINE CORTICES, RIGHT PARACENTRAL, POSTCENTRAL, SUPERIOR AND INFERIOR PARIETAL CORTICES, THE BANKS OF THE SUPERIOR TEMPORAL SULCUS, AND THE PARS OPERCULARIS. RIGHT HIPPOCAMPAL VOLUME INCREASED AFTER YOGA BUT DID NOT SURVIVE CORRECTIONS. CONCLUSION: YOGA TRAINING MAY OFFER NEUROPROTECTIVE EFFECTS COMPARED TO MET IN PREVENTING NEURODEGENERATIVE CHANGES AND COGNITIVE DECLINE, EVEN OVER SHORT TIME INTERVALS. FUTURE ANALYSES WILL ADDRESS CHANGES IN FUNCTIONAL CONNECTIVITY IN BOTH GROUPS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
2 1667  53 NEUROCHEMICAL AND NEUROANATOMICAL PLASTICITY FOLLOWING MEMORY TRAINING AND YOGA INTERVENTIONS IN OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENT. BEHAVIORAL INTERVENTIONS ARE BECOMING INCREASINGLY POPULAR APPROACHES TO AMELIORATE AGE-RELATED COGNITIVE DECLINE, BUT THEIR UNDERLYING NEUROBIOLOGICAL MECHANISMS AND CLINICAL EFFICIENCY HAVE NOT BEEN FULLY ELUCIDATED. THE PRESENT STUDY EXPLORED BRAIN PLASTICITY ASSOCIATED WITH TWO BEHAVIORAL INTERVENTIONS, MEMORY ENHANCEMENT TRAINING (MET) AND A MIND-BODY PRACTICE (YOGIC MEDITATION), IN HEALTHY SENIORS WITH MILD COGNITIVE IMPAIRMENT (MCI) USING STRUCTURAL MAGNETIC RESONANCE IMAGING (S-MRI) AND PROTON MAGNETIC RESONANCE SPECTROSCOPY ((1)H-MRS). SENIOR PARTICIPANTS (AGE >/=55 YEARS) WITH MCI WERE RANDOMIZED TO THE MET OR YOGIC MEDITATION INTERVENTIONS. FOR BOTH INTERVENTIONS, PARTICIPANTS COMPLETED EITHER MET TRAINING OR KUNDALINI YOGA (KY) FOR 60-MIN SESSIONS OVER 12 WEEKS, WITH 12-MIN DAILY HOMEWORK ASSIGNMENTS. GRAY MATTER VOLUME AND METABOLITE CONCENTRATIONS IN THE DORSAL ANTERIOR CINGULATE CORTEX (DACC) AND BILATERAL HIPPOCAMPUS WERE MEASURED BY STRUCTURAL MRI AND (1)H-MRS AT BASELINE AND AFTER 12 WEEKS OF TRAINING. METABOLITES MEASURED INCLUDED GLUTAMATE-GLUTAMINE (GLX), CHOLINE-CONTAINING COMPOUNDS (CHO, INCLUDING GLYCEROPHOSPHOCHOLINE AND PHOSPHOCHOLINE), GAMMA-AMINOBUTYRIC ACID (GABA), AND N-ACETYL ASPARTATE AND N-ACETYLASPARTYL-GLUTAMATE (NAA-NAAG). IN TOTAL, 11 PARTICIPANTS COMPLETED MET AND 14 COMPLETED YOGIC MEDITATION FOR THIS STUDY. STRUCTURAL MRI ANALYSIS SHOWED AN INTERACTION BETWEEN TIME AND GROUP IN DACC, INDICATING A TREND TOWARDS INCREASED GRAY MATTER VOLUME AFTER THE MET INTERVENTION. (1)H-MRS ANALYSIS SHOWED AN INTERACTION BETWEEN TIME AND GROUP IN CHOLINE-CONTAINING COMPOUNDS IN BILATERAL HIPPOCAMPUS, INDUCED BY SIGNIFICANT DECREASES AFTER THE MET INTERVENTION. THOUGH PRELIMINARY, OUR RESULTS SUGGEST THAT MEMORY TRAINING INDUCES STRUCTURAL AND NEUROCHEMICAL PLASTICITY IN SENIORS WITH MCI. FURTHER RESEARCH IS NEEDED TO DETERMINE WHETHER MIND-BODY INTERVENTIONS LIKE YOGA YIELD SIMILAR NEUROPLASTIC CHANGES.	2016	
                                                                                                                                                                                                                                                                                                                                               
3  447  20 CHANGED PATTERN OF REGIONAL GLUCOSE METABOLISM DURING YOGA MEDITATIVE RELAXATION. USING POSITRON EMISSION TOMOGRAPHY (PET), MEASUREMENTS OF THE REGIONAL CEREBRAL METABOLIC RATE OF GLUCOSE (RCMRGLC) ARE ABLE TO DELINEATE CEREBRAL METABOLIC RESPONSES TO EXTERNAL OR MENTAL STIMULATION. IN ORDER TO EXAMINE POSSIBLE CHANGES OF BRAIN METABOLISM DUE TO YOGA MEDITATION PET SCANS WERE PERFORMED IN 8 MEMBERS OF A YOGA MEDITATION GROUP DURING THE NORMAL CONTROL STATE (C) AND YOGA MEDITATIVE RELAXATION (YMR). WHEREAS THERE WERE INTRAINDIVIDUAL CHANGES OF THE TOTAL CMRGLC, THE ALTERATIONS WERE NOT SIGNIFICANT FOR INTERGROUP COMPARISON; SPECIFIC FOCAL CHANGES OR CHANGES IN THE INTERHEMISPHERIC DIFFERENCES IN METABOLISM WERE ALSO NOT SEEN; HOWEVER THE RATIOS OF FRONTAL VS. OCCIPITAL RCMRGLC WERE SIGNIFICANTLY ELEVATED (P LESS THAN 0.05) DURING YMR. THESE ALTERED RATIOS WERE CAUSED BY A SLIGHT INCREASE OF FRONTAL RCMRGLC AND A MORE PRONOUNCED REDUCTION IN PRIMARY AND SECONDARY VISUAL CENTERS. THESE DATA INDICATE A HOLISTIC BEHAVIOR OF THE BRAIN METABOLISM DURING THE TIME OF ALTERED STATE OF CONSCIOUSNESS DURING YMR.	1990	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
4 2257  27 THE PHYSIOLOGICAL CORRELATES OF KUNDALINI YOGA MEDITATION: A STUDY OF A YOGA MASTER. THIS STUDY EXPLORES THE PHYSIOLOGICAL CORRELATES OF A HIGHLY PRACTICED KUNDALINI YOGA MEDITATOR. THORACIC AND ABDOMINAL BREATHING PATTERNS, HEART RATE (HR), OCCIPITAL PARIETAL ELECTROENCEPHALOGRAPH (EEG), SKIN CONDUCTANCE LEVEL (SCL), AND BLOOD VOLUME PULSE (BVP) WERE MONITORED DURING PREBASELINE, MEDITATION, AND POSTBASELINE PERIODS. VISUAL ANALYSES OF THE DATA SHOWED A DECREASE IN RESPIRATION RATE DURING THE MEDITATION FROM A MEAN OF 11 BREATHS/MIN FOR THE PRE- AND 13 BREATHS/MIN FOR THE POSTBASELINE TO A MEAN OF 5 BREATHS/MIN DURING THE MEDITATION, WITH A PREDOMINANCE OF ABDOMINAL/DIAPHRAGMATIC BREATHING. THERE WAS ALSO MORE ALPHA EEG ACTIVITY DURING THE MEDITATION (M = 1.71 MICROV) COMPARED TO THE PRE- (M = .47 MICROV) AND POSTBASELINE (M = .78 MICROV) PERIODS, AND AN INCREASE IN THETA EEG ACTIVITY IMMEDIATELY FOLLOWING THE MEDITATION (M = .62 MICROV) COMPARED TO THE PRE-BASELINE AND MEDITATIVE PERIODS (EACH WITH M = .26 MICROV). THESE FINDINGS SUGGEST THAT A SHIFT IN BREATHING PATTERNS MAY CONTRIBUTE TO THE DEVELOPMENT OF ALPHA EEG, AND THOSE PATTERNS NEED TO BE INVESTIGATED FURTHER.	2001	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
5  918  25 EFFECTIVENESS OF TRAINING PROGRAM COMBINING CHAKRAYOGA AND MEDITATION. BACKGROUND THIS STUDY WAS DESIGNED TO EXAMINE THE EFFECTIVENESS OF PROGRAM COMBINING CHAKRAYOGA AND MEDITATION ON THE PHYSICAL HEALTH AND DISEASE-RELATED FACTORS AND PSYCHOLOGICAL FACTORS OF PEOPLE. METHODS NINETY-SEVEN SUBJECTS (32-83 YEARS OLD) WHO HAD FREE FROM PRIOR EXPERIENCES IN MEDITATION PROGRAMS OR CHAKRAYOGA TRAINING COURSES WERE ASSIGNED TO EITHER THE EXPERIMENTAL GROUP (EXP) (45 SUBJECTS; 13 MALE SUBJECTS AND 32 FEMALE SUBJECTS; AVERAGE AGE OF 60.67 YEARS, SD=11.09 YEARS) OR THE CONTROL GROUP (CONT) OF REMAINING SUBJECTS (52 SUBJECTS; 14 MALE SUBJECTS AND 38 FEMALE SUBJECTS; AVERAGE AGE OF 61.58 YEARS, SD=9.70 YEARS). SUBJECTS IN THE EXP PARTICIPATED IN THE CHAKRAYOGA MEDITATION PROGRAM FOR TWICE A WEEK FOR 2 H DURING 6 WEEKS IN EACH SESSION CONSISTED OF 1 H OF CHAKRAYOGA AND 1 H OF MEDITATION. THE MEASUREMENTS IN THIS STUDY INCLUDED THE MINDFULNESS, STRESS RESPONSE, SUBJECTIVE QUALITY OF LIFE, MEDICAL SYMPTOM CHECKLIST, DIFFICULTY IN EMOTIONAL REGULATION AND OBJECTIVE OF LIFE AND SENSE OF CONTROL. RESULTS RESULTS REVEALED THAT PARTICIPANTS IN THE EXP REPORTED SIGNIFICANTLY MORE RELIEF OF MINDFULNESS, STRESS RESPONSE, SUBJECTIVE QUALITY OF LIFE AND MEDICAL SYMPTOM CHECKLIST THAN THOSE IN THE CONT. CONCLUSIONS THESE FINDINGS PROVIDE EVIDENCE THAT THE CHAKRAYOGA MEDITATION PROGRAM CAN HELP RELIEVE THE PHYSICAL HEALTH AND DISEASE-RELATED FACTORS AND PSYCHOLOGICAL FACTORS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
6  712  32 EFFECT OF INTEGRATED YOGA ON ANTI-PSYCHOTIC INDUCED SIDE EFFECTS AND COGNITIVE FUNCTIONS IN PATIENTS SUFFERING FROM SCHIZOPHRENIA. BACKGROUND TWENTY ONE (12 FEMALES) SUBJECTS, DIAGNOSED WITH SCHIZOPHRENIA BY A PSYCHIATRIST USING ICD-10, IN THE AGES 52.87 + 9.5YEARS AND SUFFERING SINCE 24.0 +/- 3.05YEARS WERE RECRUITED INTO THE STUDY FROM A SCHIZOPHRENIA REHABILITATION CENTER IN BENGALURU. METHODS ALL SUBJECTS WERE TAKING ANTI-PSYCHOTIC MEDICATIONS AND WERE IN STABLE STATE FOR MORE THAN A MONTH. PSYCHIATRIC MEDICATIONS WERE KEPT CONSTANT DURING THE STUDY PERIOD. ASSESSMENTS WERE DONE AT THREE POINTS OF TIME: (1) BASELINE, (2) AFTER ONE MONTH OF USUAL ROUTINE (PRE) AND (3) AFTER FIVE MONTHS OF VALIDATED INTEGRATED YOGA (IY) INTERVENTION (POST). VALIDATED 1H YOGA MODULE (CONSISTING OF ASANAS, PRANAYAMA, RELAXATION TECHNIQUES AND CHANTINGS) WAS PRACTICED FOR 5MONTHS, FIVE SESSIONS PER WEEK. ANTIPSYCHOTIC-INDUCED SIDE EFFECTS WERE ASSESSED USING SIMPSON ANGUS SCALE (SAS) AND UDVALG FOR KLINISKE UNDERSOGELSER (UKU) SIDE EFFECT RATING SCALE. COGNITIVE FUNCTIONS (USING TRAIL MAKING TEST A AND B), CLINICAL SYMPTOMS AND ANTHROPOMETRY WERE ASSESSED AS SECONDARY VARIABLES. COMPARISONS BETWEEN "PRE" AND "POST" DATA WAS DONE USING PAIRED SAMPLES T-TESTS AFTER SUBTRACTING BASELINE SCORES FROM THEM RESPECTIVELY. RESULTS AT THE END OF FIVE MONTHS, SIGNIFICANT REDUCTION IN DRUG-INDUCED PARKINSONIAN SYMPTOMS (SAS SCORE; P=0.001) AND 38 ITEMS OF UKU SCALE WAS OBSERVED ALONG WITH SIGNIFICANT IMPROVEMENT IN PROCESSING SPEED, EXECUTIVE FUNCTIONS AND NEGATIVE SYMPTOMS OF SCHIZOPHRENIA PATIENTS. NO SIDE EFFECTS OF YOGA WERE REPORTED. CONCLUSIONS THE PRESENT STUDY PROVIDES PRELIMINARY EVIDENCE FOR USEFULNESS OF INTEGRATED YOGA INTERVENTION IN MANAGING ANTI-PSYCHOTIC-INDUCED SIDE EFFECTS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
7  769  39 EFFECT OF UNILATERAL LEFT NOSTRIL BREATHING (CHANDRA ANGA PRANAYAMA) ON COGNITIVE FUNCTION IN HEALTHY YOGA-NAIVE INDIVIDUALS: A RANDOMIZED, CONTROLLED, PILOT STUDY. INTRODUCTION: BREATHING MODULATES CORTICAL NEURONAL ACTIVITY. VARIOUS BREATHING EXERCISES ARE PURPORTED TO HAVE SPECIFIC EFFECTS ON EMOTIONAL AND COGNITIVE FUNCTIONS. OBJECTIVE: TO DETERMINE THE EFFECT OF UNILATERAL LEFT NOSTRIL BREATHING (ULNB) ON NONLATERALIZED, OVERALL COGNITIVE FUNCTIONS USING COMPUTERIZED PSYCHOMETRIC TESTS. METHODS: A RANDOMIZED, CONTROLLED, PILOT STUDY WAS CONDUCTED AMONG 20 HEALTHY YOGA-NAIVE MEDICAL STUDENTS. ULNB WAS PERFORMED FOR 15 MIN BY THE TEST GROUP (N = 10) AND BREATH AWARENESS BY THE CONTROL GROUP (N = 10). ATTENTION AND PROCESSING SPEED, MEMORY, AND EXECUTIVE FUNCTION WERE ASSESSED USING THE LETTER-DIGIT SUBSTITUTION TEST, STERNBERG MEMORY TASK, AND VICTORIA STROOP TEST, RESPECTIVELY. BASELINE, PRE- AND POSTINTERVENTION SCORES WERE RECORDED. RESULTS: THERE WAS NO SIGNIFICANT DIFFERENCE BETWEEN THE GROUPS IN BASELINE SCORES. IN THE STERNBERG MEMORY TASK, A STATISTICALLY SIGNIFICANT DECREASE IN RESPONSE TIME WAS SEEN IN THE TEST (T(9) = 3.855, P = 0.004) AS WELL AS THE CONTROL GROUP (T(9) = 3.120, P = 0.012); THERE WAS NO SIGNIFICANT DIFFERENCE BETWEEN THE GROUPS. NO SIGNIFICANT EFFECT OF UNLB WAS SEEN IN THE LETTER-DIGIT SUBSTITUTION TEST AND STROOP TEST. CONCLUSIONS: OUR STUDY SHOWED NO DIFFERENCE IN THE EFFECTS OF 15-MIN PRACTICE OF ULNB AND BREATH AWARENESS ON COGNITIVE FUNCTIONS; BOTH IMPROVED MEMORY BUT NOT ATTENTION OR EXECUTIVE FUNCTION.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
8 2396  16 YOGA AND CHEMOREFLEX RESPONSE TO HYPOXIA AND HYPERCAPNIA. WE TESTED WHETHER CHEMOREFLEX SENSITIVITY COULD BE AFFECTED BY THE PRACTICE OF YOGA, AND WHETHER THIS IS SPECIFICALLY BECAUSE OF A SLOW BREATHING RATE OBTAINED DURING YOGA OR AS A GENERAL CONSEQUENCE OF YOGA. WE FOUND THAT SLOW BREATHING RATE PER SE SUBSTANTIALLY REDUCED CHEMOREFLEX SENSITIVITY, BUT LONG-TERM YOGA PRACTICE WAS RESPONSIBLE FOR A GENERALISED REDUCTION IN CHEMOREFLEX.	2000	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
9  441  39 CEREBRAL BLOOD FLOW EFFECTS OF YOGA TRAINING: PRELIMINARY EVALUATION OF 4 CASES. OBJECTIVES: EXPERIENCED PRACTITIONERS OF YOGA HAVE BEEN SHOWN TO ALTER BRAIN FUNCTION, BUT THIS CASE SERIES MEASURED CEREBRAL BLOOD FLOW BEFORE AND AFTER A 12-WEEK TRAINING PROGRAM IN IYENGAR YOGA (IY) FOR NAIVE SUBJECTS. METHODS: ON THE FIRST DAY, EACH OF THE 4 SUBJECTS LISTENED TO THE TEACHER SPEAKING ON THE HISTORY AND BACKGROUND OF THE YOGA PROGRAM WHILE THEY WERE INJECTED WITH 250 MBQ OF (99M)TC-BICISATE AND RECEIVED A SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY SCAN (PRE-PROGRAM BASELINE). SUBJECTS THEN HAD THEIR FIRST IY TRAINING AND WERE INJECTED AND SCANNED WITH 925 MBQ BICISATE WHILE THEY DID THEIR FIRST MEDITATION (PRE-PROGRAM MEDITATION). SUBJECTS THEN UNDERWENT A 12-WEEK TRAINING PROGRAM IN IY AND THEN UNDERWENT THE SAME IMAGING PROTOCOL WITH A POSTPROGRAM BASELINE AND POSTPROGRAM MEDITATION SCAN. BASELINE AND MEDITATION SCANS, BEFORE AND AFTER TRAINING, WERE COMPARED USING PAIRED T TESTS. RESULTS: THERE WERE SIGNIFICANT DECREASES (P < 0.05) BETWEEN THE PRE- AND POSTPROGRAM BASELINE SCANS IN THE RIGHT AMYGDALA, DORSAL MEDIAL CORTEX, AND SENSORIMOTOR AREA. THERE WAS A SIGNIFICANT DIFFERENCE (P < 0.05) IN THE PRE- AND POSTPROGRAM PERCENTAGE CHANGE (I.E., ACTIVATION) IN THE RIGHT DORSAL MEDIAL FRONTAL LOBE, PREFRONTAL CORTEX, AND RIGHT SENSORIMOTOR CORTEX. CONCLUSIONS: THESE INITIAL FINDINGS SUGGEST THE BRAIN EXPERIENCES A "TRAINING EFFECT" AFTER 12 WEEKS OF IY TRAINING.	2009	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
10 2905  37 [LONG-TERM EFFECTS OF BREATHING EXERCISES AND YOGA IN PATIENTS WITH BRONCHIAL ASTHMA]. TO COMPARE THE EFFECTS OF BREATHING EXERCISES (BE) OR YOGA (Y) ON THE COURSE OF BRONCHIAL ASTHMA WE STUDIED 36 SUBJECTS WITH A MILD DISEASE. THE PATIENTS WERE RANDOMLY DIVIDED INTO 3 GROUPS. 2 OF THEM PARTICIPATED IN A 3 WEEKS TRAINING PROGRAM OF BE OR Y WHILE THE THIRD GROUP RESTED WITHOUT ANY ADDITIONAL TREATMENT (CONTROL GROUP, C). AT THE END OF THE TRAINING PERIOD THE PATIENTS WERE ASKED TO PRACTISE BE OR Y ON THEIR OWN. DRUG THERAPY AND LUNG FUNCTION PARAMETERS BEFORE AND AFTER A BETA 2-AGONIST METERED DOSE INHALER (ALBUTEROL, ALB) WERE RECORDED PRIOR TO THE TRAINING PROGRAM AND IN 4 WEEKS INTERVALS FOR 4 MONTHS THEREAFTER. THE RESPONSE TO THE BETA 2-AGONIST WAS DOCUMENTED CONTINUOUSLY IN 28 PATIENTS. THE MENTAL STATE OF THE PATIENTS WAS ELUCIDATED BY QUESTIONNAIRES.--PRIOR TO THE STUDY A SIGNIFICANT EFFECT OF INHALED ALB ON THE FEV1 WAS SHOWN WITHOUT ANY SIGNIFICANT BETWEEN GROUP DIFFERENCES. BOTH, BE AND Y, CAUSED A SIGNIFICANT AMELIORATION OF THE MENTAL STATE BUT ONLY THE BE INDUCED A SIGNIFICANT IMPROVEMENT OF LUNG FUNCTION PARAMETERS COMPARED TO THE INDIVIDUAL BASELINE VALUES. THE FEV1 INCREASED SIGNIFICANTLY BY 356.3 +/- 146.2 ML (P < 0.05) AND THE VC BY 225.0 +/- 65.5 ML (P < 0.01). THESE LONG-TERM CHANGES WERE NOT SIGNIFICANTLY DIFFERENT FROM THE ACTUAL RESPONSE TO ALB. BE DECREASED THE RV SIGNIFICANTLY BY 306.3 +/- 111.6 ML (P < 0.05), AN EFFECT SIGNIFICANTLY HIGHER COMPARED TO THE BETA 2-AGONIST (P < 0.01). BE IN COMBINATION WITH ALB CAUSED AN ADDITIVE EFFECT.(ABSTRACT TRUNCATED AT 250 WORDS)	1994	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
11 2757  26 YOGA PRACTICES AND PSYCHOLOGICAL WELL-BEING OF STUDENT NURSES. YOGA HAS BEEN WITH US SINCE TIME IMMEMORIAL, BUT IT IS ONLY DURING RECENT YEARS THAT IT HAS ASSUMED WORLDWIDE IMPORTANCE. THE AIM OF THE STUDY WAS TO ASSESS THE CT OF SELECTED YOGA PRACTICES ON PSYCHOLOGICAL WELLBEING. IN THIS QUASI-EXPERIMENTAL ONE GROUP PRE-TEST AND POST- TEST STUDY, 83 UNDER GRADUATE STUDENT NURSES. WERE TAUGHT SELECTED YOGA EXERCISES. THE SE- LECTED YOGA EXERCISES WERE SYSTEMATIC RELAXATION, BREATHING, AND STRETCHING THAT WERE PER- FORMED IN THE FORMATIVE MANNER. THE' INTERVENTION WAS CARRIED OUT FOR THE MINIMAL DURATION OF ONE HOUR PER DAY, THREE DAYS A WEEK FOR A PERIOD OF 6 WEEKS. ASSESSMENT WAS- CARRIED OUT ON THE FIRST AND LAST- DAY OF THE INTERVENTION, USING-A MODIFIED HINDI VERSION OF POSITIVE AFFECT AND NEGATIVE AFFECT SCALE, (PANAS-H). IT,HAS 10 QUESTIONS EACH TO MEASURE POSITIVE (PA) AND NEGA- TIVE AFFECT (NA). SINCE THE DATA WAS TESTED AND FORMED A NORMAL DISTRIBUTION, THE PAIRED 'T' TEST WAS USED FOR STATISTICAL ANALYSIS. THE. MEAN PA SCORE OF 42.92 AFTER YOGA PRACTICE WAS STATISTI- CALLY HIGHER THAN THE MEAN PA SCORE OF 32. 50 BEFORE YOGA PRACTICE (P=O. 01). THE MEAN NA SCORE OF 20.75 AFTER YOGA PRACTICE WAS LOWER THAN THE MEAN NA SCORE OF 23.33 BEFORE YOGA PRACTICE (P=0.427). THE YOGA PRACTICE CAN BE TAUGHT TO NORMALPARTICIPANTS AS IT MAY REDUCE NEGATIVE AFFECT AND INCREASE THE POSITIVE AFFECT WITHIN A FEW WEEKS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
12 1629  24 MINDFULNESS-BASED YOGA FOR YOUTH WITH PERSISTENT CONCUSSION: A PILOT STUDY. OBJECTIVE: WE EXPLORED THE POTENTIAL IMPACT OF MINDFULNESS-BASED YOGA (MBY) FOR YOUTH WITH PERSISTENT CONCUSSION BY EXAMINING OCCUPATION-BASED AND NEUROPHYSIOLOGICAL OUTCOMES. METHOD: IN THIS CASE SERIES DESIGN STUDY, 6 YOUTHS AGES 13-17 YR WITH CONCUSSION SYMPTOMS FOR >4 WK PARTICIPATED IN AN 8-WK MBY INTERVENTION, 1X/WK FOR 45 MIN. PARTICIPATION, SELF-EFFICACY, AND HEART RATE VARIABILITY (24 HR) WERE COLLECTED BEFORE, AFTER, AND 3 MO AFTER THE INTERVENTION. HEART RATE VARIABILITY WAS ALSO MEASURED DURING EACH SESSION. RESULTS: TRENDS OF INCREASED SELF-EFFICACY IN ACADEMIC, SOCIAL, AND EMOTIONAL DOMAINS WERE FOUND AFTER MBY AND MAINTAINED AT 3-MO FOLLOW-UP. TRENDS OF INCREASING HEART RATE VARIABILITY WERE ALSO FOUND PRE- TO POSTINTERVENTION AND WITHIN THE EIGHT MBY SESSIONS. CONCLUSION: PRELIMINARY RESULTS REVEAL POSITIVE TRENDS AFTER A NOVEL, SAFE INTERVENTION FOR YOUTH WITH PERSISTENT CONCUSSION SYMPTOMS AND THE VALUE OF EXPLORING BOTH OCCUPATION-BASED AND NEUROPHYSIOLOGICAL MEASURES. FUTURE RESEARCH WITH A LARGER SAMPLE AND CONTROL GROUP IS WARRANTED.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
13 2890  27 YOGA: POTENTIAL BENEFITS FOR PERSONS WHO STUTTER. YOGA HAS BEEN DEMONSTRATED TO MODULATE AUTONOMIC NERVOUS SYSTEM ACTIVITY, DECREASING ANXIETY AND STRESS, AND IMPROVING QUALITY OF LIFE. THIS PRELIMINARY STUDY SOUGHT TO EXAMINE THE USE OF YOGIC TECHNIQUES ON PERSONS WHO STUTTER GIVEN THE INTERACTION BETWEEN PHYSIOLOGICAL AROUSAL/ANXIETY AND STUTTERING THAT CURRENT MULTIFACTORIAL MODELS OF STUTTERING PROPOSE. FOUR PARTICIPANTS (M = 52 YR, SD = 10; 2 FEMALE, 2 MALE), RECRUITED FROM LOCAL STUTTERING SUPPORT GROUPS IN THE GREATER PHILADELPHIA COMMUNITY VOLUNTEERED TO PARTICIPATE. STUTTERING SEVERITY, ANXIETY, AND EXPERIENCES REGARDING STUTTERING AND COMMUNICATION WERE MEASURED AT BASELINE, POST INTERVENTION, AND AT 4 MONTHS FOLLOW-UP. THE PARTICIPANTS ATTENDED GROUP YOGA SESSIONS AND ENGAGED IN HOME PRACTICE. DESCRIPTIVE RESULTS REVEALED THAT PARTICIPANTS SHOWED IMPROVEMENTS ACROSS OUTCOME MEASURES, WITH THE MOST IMPROVEMENT RELATED TO ANXIETY. PARTICIPANTS ALSO REPORTED IMPROVEMENTS IN THEIR PERCEPTIONS ABOUT COMMUNICATION AS PER QUALITATIVE ANALYSIS OF RESPONSES TO THE OPEN-ENDED QUESTIONNAIRES. THE RESULTS SUGGEST THE POTENTIAL BENEFITS OF YOGA FOR PERSONS WHO STUTTER AND WARRANTS FURTHER STUDY USING AN EXPERIMENTAL DESIGN.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
14 1496  35 INTRACEREBRAL PAIN PROCESSING IN A YOGA MASTER WHO CLAIMS NOT TO FEEL PAIN DURING MEDITATION. WE RECORDED MAGNETOENCEPHALOGRAPHY (MEG) AND FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI) FOLLOWING NOXIOUS LASER STIMULATION IN A YOGA MASTER WHO CLAIMS NOT TO FEEL PAIN WHEN MEDITATING. AS FOR BACKGROUND MEG ACTIVITY, THE POWER OF ALPHA FREQUENCY BANDS PEAKING AT AROUND 10 HZ WAS MUCH INCREASED DURING MEDITATION OVER OCCIPITAL, PARIETAL AND TEMPORAL REGIONS, WHEN COMPARED WITH THE NON-MEDITATIVE STATE, WHICH MIGHT MEAN THE SUBJECT WAS VERY RELAXED, THOUGH HE DID NOT FALL ASLEEP, DURING MEDITATION. PRIMARY PAIN-RELATED CORTICAL ACTIVITIES RECORDED FROM PRIMARY (SI) AND SECONDARY SOMATOSENSORY CORTICES (SII) BY MEG WERE VERY WEAK OR ABSENT DURING MEDITATION. AS FOR FMRI RECORDING, THERE WERE REMARKABLE CHANGES IN LEVELS OF ACTIVITY IN THE THALAMUS, SII-INSULA (MAINLY THE INSULA) AND CINGULATE CORTEX BETWEEN MEDITATION AND NON-MEDITATION. ACTIVITIES IN ALL THREE REGIONS WERE INCREASED DURING NON-MEDITATION, SIMILAR TO RESULTS IN NORMAL SUBJECTS. IN CONTRAST, ACTIVITIES IN ALL THREE REGIONS WERE WEAKER DURING MEDITATION, AND THE LEVEL WAS LOWER THAN THE BASELINE IN THE THALAMUS. RECENT NEUROIMAGING AND ELECTROPHYSIOLOGICAL STUDIES HAVE CLARIFIED THAT THE EMOTIONAL ASPECT OF PAIN PERCEPTION MAINLY INVOLVES THE INSULA AND CINGULATE CORTEX. THOUGH WE CANNOT CLEARLY EXPLAIN THIS UNUSUAL CONDITION IN THE YOGA MASTER, A CHANGE OF MULTIPLE REGIONS RELATING TO PAIN PERCEPTION COULD BE RESPONSIBLE, SINCE PAIN IS A COMPLEX SENSORY AND EMOTIONAL EXPERIENCE.	2005	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
15 1932  35 ROLE OF YOGA IN MODIFYING ANXIETY LEVEL IN WOMEN. ANXIETY LEADS TO DERANGEMENT IN PHYSICAL AND MENTAL HEALTH. ANXIETY LEVELS ARE MORE IN FULL TIME HOUSEWIVES THAN WORKING WOMEN. THERE IS A NEED FOR SIMPLE, EASY TREATMENT FOR ANXIETY TO ALLEVIATE THE BURDEN ON HEALTH CAUSED BY ANXIETY. YOGA IS AMONG THE TOP TEN COMPLEMENTARY AND ALTERNATIVE MEDICINE THERAPIES. OUR STUDY AIMED TO DETERMINE THE ANXIETY LEVELS IN APPARENTLY HEALTHY FULL TIME HOUSEWIVES AND TO STUDY THE EFFECTS OF YOGA ON ANXIETY LEVELS AMONG THEM. PRESENT STUDY IS A COMPARATIVE INTERVENTIONAL STUDY. STUDY WAS CONDUCTED ON 50 APPARENTLY HEALTHY FULL TIME HOUSEWIVES (20-50 YEARS) WHO ATTENDED ONE MONTH YOGA CAMP. HAMILTON ANXIETY (HAMA) SCALE WAS USED TO EVALUATE ANXIETY LEVELS BEFORE AND AT THE END OF THE YOGA CAMP. STATISTICAL ANALYSIS WAS DONE BY PAIRED T TEST USING SPSS 9.0. THE BASELINE PULSE RATE, SBP, DBP WERE 82.90 +/- 4.25 BPM, 124.84 +/- 11.022 MM HG, 85.20 +/- 10.81 MM HG RESPECTIVELY. AFTER FOUR WEEKS YOGA CAMP THERE WAS STATISTICALLY SIGNIFICANT LOWERING OF PULSE RATE (77.58 +/- 3.86 BPM), SBP (117.92 +/- 6.76 MM HG), DBP (78.68 +/- 6.62 MM HG). BEFORE YOGA TRAINING, PERCENTAGE DISTRIBUTIONS OF SUBJECTS WITH MILD, MODERATE AND SEVERE ANXIETY WERE 6%, 18% AND 76% RESPECTIVELY. AT THE END OF FOUR WEEK YOGA TRAINING, PERCENTAGE DISTRIBUTIONS OF SUBJECTS WITH MILD, MODERATE AND SEVERE ANXIETY WERE 44.23%, 19.23% AND 36.53% RESPECTIVELY. THERE WAS HIGHLY SIGNIFICANT (P = 0.000) DIFFERENCE IN THE MEAN VALUES OF TOTAL SCORE BEFORE (33.71 +/- 4.90) AND AFTER (26.93 +/- 4.53) YOGA. THESE RESULTS INDICATE THAT THERE WAS A REDUCTION IN THE SEVERITY OF ANXIETY FROM SEVERE TO MODERATE AND MILD INDICATING DECREASE IN ANXIETY FOLLOWING YOGA. BASED ON THE RESULTS OF OUR STUDY, WE CONCLUDE THAT REGULAR YOGIC PRACTICES AND ADAPTING AND IMPLEMENTING THE PRINCIPALS AND PHILOSOPHY OF YOGA IN DAY TO DAY LIFE MAY DECREASE THE ANXIETY LEVEL.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
16 1603  18 MENTAL DEPRESSION AND KUNDALINI YOGA. IN CASES OF MENTAL DEPRESSION, THE PLASMA SEROTONIN, MELATONIN AND GLUTAMATE LEVELS ARE INCREASED ALONG WITH THE LOWERING OF URINARY - 5 - HYDROXYINDOLE ACETIC ACID, PLASMA MONOAMINE OXIDASE AND CORTISOL LEVELS FOLLOWING THREE AND SIX MONTHS PRACTICE OF KUNDALINI YOGA. THE PULSE RATE AND BLOOD PRESSURE IN THESE PATIENTS ARE ALSO LOWERED AFTER KUNDALINI YOGA PRACTICE. THUS, THE PRACTICE OF KUNDALINI YOGA HELPS TO MAINTAIN A PERFECT HOMEOSTASIS BY BRINGING AN EQUILIBRIUM BETWEEN THE SYMPATHETIC AND PARASYMPATHETIC ACTIVITIES AND IT CAN BE USED AS A NON - MEDICAL MEASURE IN TREATING PATIENTS WITH MENTAL DEPRESSION.	1986	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
17 1468  36 INNER ENGINEERING PRACTICES AND ADVANCED 4-DAY ISHA YOGA RETREAT ARE ASSOCIATED WITH CANNABIMIMETIC EFFECTS WITH INCREASED ENDOCANNABINOIDS AND SHORT-TERM AND SUSTAINED IMPROVEMENT IN MENTAL HEALTH: A PROSPECTIVE OBSERVATIONAL STUDY OF MEDITATORS. BACKGROUND: ANXIETY AND DEPRESSION ARE COMMON IN THE MODERN WORLD, AND THERE IS GROWING DEMAND FOR ALTERNATIVE THERAPIES SUCH AS MEDITATION. MEDITATION CAN DECREASE PERCEIVED STRESS AND INCREASE GENERAL WELL-BEING, ALTHOUGH THE PHYSIOLOGICAL MECHANISM IS NOT WELL-CHARACTERIZED. ENDOCANNABINOIDS (ECBS), LIPID MEDIATORS ASSOCIATED WITH ENHANCED MOOD AND REDUCED ANXIETY/DEPRESSION, HAVE NOT BEEN PREVIOUSLY STUDIED AS BIOMARKERS OF MEDITATION EFFECTS. OUR AIM WAS TO ASSESS BIOMARKERS (ECBS AND BRAIN-DERIVED NEUROTROPHIC FACTOR [BDNF]) AND PSYCHOLOGICAL PARAMETERS AFTER A MEDITATION RETREAT. METHODS: THIS WAS AN OBSERVATIONAL PILOT STUDY OF ADULTS BEFORE AND AFTER THE 4-DAY ISHA YOGA BHAVA SPANDANA PROGRAM RETREAT. PARTICIPANTS COMPLETED ONLINE SURVEYS (BEFORE AND AFTER RETREAT, AND 1 MONTH LATER) TO ASSESS ANXIETY, DEPRESSION, FOCUS, WELL-BEING, AND HAPPINESS THROUGH VALIDATED PSYCHOLOGICAL SCALES. VOLUNTARY BLOOD SAMPLING FOR BIOMARKER STUDIES WAS DONE BEFORE AND WITHIN A DAY AFTER THE RETREAT. THE BIOMARKERS ANANDAMIDE, 2-ARACHIDONOYLGLYCEROL (2-AG), 1-ARACHIDONOYLGLYCEROL (1-AG), DOCOSATETRAENOYLETHANOLAMIDE (DEA), OLEOYLETHANOLAMIDE (OLA), AND BDNF WERE EVALUATED. PRIMARY OUTCOMES WERE CHANGES IN PSYCHOLOGICAL SCALES, AS WELL AS CHANGES IN ECBS AND BDNF. RESULTS: DEPRESSION AND ANXIETY SCORES DECREASED WHILE FOCUS, HAPPINESS, AND POSITIVE WELL-BEING SCORES INCREASED IMMEDIATELY AFTER RETREAT FROM THEIR BASELINE VALUES (P < 0.001). ALL IMPROVEMENTS WERE SUSTAINED 1 MONTH AFTER BSP. ALL MAJOR ECBS INCLUDING ANANDAMIDE, 2-AG, 1-AG, DEA, AND BDNF INCREASED AFTER MEDITATION BY > 70% (P < 0.001). INCREASES OF >/=20% IN ANANDAMIDE, 2-AG, 1-AG, AND TOTAL AG LEVELS AFTER MEDITATION FROM THE BASELINE HAD WEAK CORRELATIONS WITH CHANGES IN HAPPINESS AND WELL-BEING. CONCLUSIONS: A SHORT MEDITATION EXPERIENCE IMPROVED FOCUS, HAPPINESS, AND POSITIVE WELL-BEING AND REDUCED DEPRESSION AND ANXIETY IN PARTICIPANTS FOR AT LEAST 1 MONTH. PARTICIPANTS HAD INCREASED BLOOD ECBS AND BDNF, SUGGESTING A ROLE FOR THESE BIOMARKERS IN THE UNDERLYING MECHANISM OF MEDITATION. MEDITATION IS A SIMPLE, ORGANIC, AND EFFECTIVE WAY TO IMPROVE WELL-BEING AND REDUCE DEPRESSION AND ANXIETY.	2020	

18 1131  40 EFFICACY OF YOGA FOR MENTAL PERFORMANCE IN UNIVERSITY STUDENTS. BACKGROUND: WITH GROWING SCIENTIFIC EVIDENCE, YOGA IS EMERGING AS AN IMPORTANT HEALTH BEHAVIOR-LIFESTYLE MODIFYING MODULE TO ACHIEVE HOLISTIC HEALTH AT PHYSICAL, MENTAL, EMOTIONAL, SOCIAL AND SPIRITUAL LEVELS. BRAIN WAVE COHERENCE (BWC) RECORDINGS FROM THE SURFACE OF THE SKULL ARE ASSOCIATED WITH DIFFERENT COGNITIVE PROCESSES AND PLAYS BOTH CRITICAL AND USEFUL ROLES IN YOGA WITH WIDE RANGE OF FUNCTIONAL SIGNIFICANCE. THE PSYCHO-PHYSIOLOGICAL CHANGES THAT CHARACTERIZE THE EFFICACY OF YOGA FOR BETTER MENTAL PERFORMANCE IN UNIVERSITY STUDENTS HAVE NOT BEEN STUDIED ADEQUATELY. OBJECTIVE: THE STUDY WAS DESIGNED TO ASSESS THE MENTAL PERFORMANCE THROUGH BWC ANALYSIS IN UNIVERSITY STUDENTS UNDERGOING INTEGRATED YOGA MODULE (IYM). MATERIALS AND METHODS: THE IYM SUBJECTS (N=30) WITH 25.77+/-4.85 YEARS OF MEAN AGE PARTICIPATED IN THIS SINGLE GROUP PRE-POST STUDY. THE BWC DATA WAS COLLECTED BEFORE (PRE) AND AFTER (POST) THE 21 DAYS IYM USING BRAIN MASTER (MODEL: 2E PART # 390-001), MICHIGAN, USA. STATISTICAL ANALYSIS: MEANS, STANDARD DEVIATIONS, KOLMOGOROV-SMIRNOV TEST AND WILCOXON SIGNED RANK TEST WERE USED FOR ANALYZING DATA WITH THE HELP OF SPSS-16. RESULTS: A COMPLETE STATISTICAL AND SPECTRAL ANALYSIS SHOWED 43.24% INCREASE (P<0.001) IN DELTA, 9.13% INCREASE (P=0.289) IN THETA, 57.85% INCREASE (P<0.001) IN ALPHA, 17.65% DECREASE (P=0.136) IN BETA AND 9.19% INCREASE (P=0.586) IN GAMMA BWC BETWEEN PRE AND POST INTERVENTION MEASUREMENTS. CONCLUSION: BWC STUDY SHOWED SIGNIFICANT INCREASE IN BOTH DELTA AND ALPHA WAVE COHERENCE SUGGESTING THAT IYM CAN RESULT IN IMPROVEMENT OF COHERENT AND INTEGRATED BRAIN FUNCTIONING AMONG STUDENTS, THUS PAVING THE WAY FOR THEIR BETTER MENTAL PERFORMANCE. ALTHOUGH THIS PRELIMINARY RESEARCH IS PROMISING, MORE WELL-DESIGNED STUDIES ARE NEEDED BEFORE A STRONG RECOMMENDATION CAN BE MADE.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
19  830  32 EFFECT OF YOGA ON MENTAL HEALTH: COMPARATIVE STUDY BETWEEN YOUNG AND SENIOR SUBJECTS IN JAPAN. BACKGROUND: JAPAN HAS A LARGE NUMBER OF SENIOR CITIZENS. YOGA CAN BE WISELY APPLIED IN OLD AGE CARE. THERE IS NO ANY AGE RESTRICTION TO PRACTICE YOGA. THE EFFECT MAY DIFFER BY AGE. THERE IS A NEED TO STUDY THE MECHANISM OF ACTION OF YOGA WITH RESPECT TO AGE. AIM: THIS STUDY WAS CONDUCTED IN JAPAN TO FIND THE EFFECT OF YOGA ON MENTAL HEALTH BETWEEN YOUNG AND SENIOR PEOPLE. MATERIALS AND METHODS: TWENTY-FIVE NORMAL HEALTHY VOLUNTEERS OF BOTH SEXES WERE DIVIDED INTO TWO GROUPS ACCORDING TO AGE. FIFTEEN PARTICIPANTS OF THE AGE GROUP BETWEEN 65 TO 75 YEARS AND 10 PARTICIPANTS OF THE AGE GROUP BETWEEN 20 TO 30 YEARS WERE SELECTED. THIS STUDY WAS APPROVED BY THE ETHICAL COMMITTEE OF KAWASAKI UNIVERSITY OF MEDICAL WELFARE. SELECTED INDIVIDUALS WERE SUBJECTED TO 90 MIN OF YOGA CLASSES ONCE OR TWICE A WEEK FOR A MONTH. SALIVARY AMYLASE ACTIVITY WAS ASSESSED BEFORE AND AFTER YOGA PRACTICE. STATE TRAIT ANXIETY INVENTORY (STAI) WAS GIVEN BEFORE YOGA ON THE FIRST DAY AND AFTER ONE MONTH OF PRACTICE TO ASSESS THE CHANGE IN STATE ANXIETY AND TRAIT ANXIETY. RESULTS: SENIOR GROUP - SALIVARY AMYLASE ACTIVITY DECREASED FROM 111.2+/-42.7 TO 83.48+/-39.5 KU/L [AVERAGE+/-STANDARD DEVIATION]. YOUNGER GROUP - SALIVARY AMYLASE ACTIVITY REDUCED FROM 60.74+/-31.8 TO 42.39+/-24 KU/L. SENIOR GROUP - STATE ANXIETY SCORE DECREASED FROM 41.13 +/-8.43 TO 30.8+/-6.49, TRAIT ANXIETY SCORE REDUCED FROM 45.66+/-7.5 TO 40.73+/-8.3. YOUNGER GROUP - STATE ANXIETY SCORE REDUCED FROM 38.7+/-4.8 TO 30.8+/-4.1,TRAIT ANXIETY SCORE REDUCED FROM 46.2+/-7.9 TO 42.9+/-9.1. CHANGES WERE STATISTICALLY SIGNIFICANT WITH P<0.05. CONCLUSION: DECREASE IN SALIVARY AMYLASE ACTIVITY MAY BE DUE TO REDUCTION IN SYMPATHETIC RESPONSE. REDUCTION IN STATE AND TRAIT ANXIETY SCORE SIGNIFIES THAT YOGA HAS BOTH IMMEDIATE AS WELL AS LONG-TERM EFFECT ON ANXIETY REDUCTION. THUS YOGA HELPS TO IMPROVE THE MENTAL HEALTH IN BOTH THE GROUPS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                            
20 2115  26 THE EFFECT OF YOGA ON THE QUALITY OF LIFE IN THE CHILDREN AND ADOLESCENTS WITH HAEMOPHILIA. THE PROBLEMS CAUSED BY HAEMOPHILIA LEAD TO IMPAIRMENTS OF THE QUALITY OF LIFE IN PATIENTS WITH HAEMOPHILIA. THIS STUDY AIMED TO INVESTIGATE THE EFFECTS OF YOGA ON QUALITY OF LIFE IN THE CHILDREN AND ADOLESCENTS WITH HAEMOPHILIA IN SHIRAZ, IRAN. THIS SEMI-EXPERIMENTAL STUDY WITH PRE- AND POST-TEST DESIGN WAS PERFORMED ON 27 BOYS BETWEEN 8 AND 16 YEARS OLD WHO SUFFERED FROM HAEMOPHILIA. THE PATIENTS WERE DIVIDED INTO TWO GROUPS. THE NUMBER OF BLEEDINGS, ABSENCES FROM SCHOOL, AND REFERRALS TO THE CLINIC WAS EVALUATED. THE DEMOGRAPHIC DATA WERE COLLECTED THROUGH INTERVIEWS AND USING THE PATIENTS' RECORDS IN THE HAEMOPHILIA CENTER. BESIDES, THE QUALITY OF LIFE WAS ASSESSED THROUGH THE HAEMO-QOL QUESTIONNAIRE. THEN, THE YOGA INTERVENTION WAS PERFORMED FOR 14 WEEKS AND THE DATA WERE COLLECTED IN THREE STAGES. THE COLLECTED DATA WERE ENTERED INTO THE SPSS STATISTICAL SOFTWARE, VERSION 18 AND WERE ANALYZED USING NON-PARAMETRIC FRIEDMAN TEST. AFTER THE INTERVENTION, SIGNIFICANT DIFFERENCES WERE OBSERVED IN THE MEAN SCORES OF QUALITY OF LIFE DIMENSIONS AND THE NUMBER OF BLEEDINGS, SCHOOL ABSENCES, AND REFERRALS TO THE HAEMOPHILIA CLINIC (P<0.001). THUS, YOGA MAY IMPROVE THE HAEMOPHILIA CHILDREN'S AND ADOLESCENTS' PERCEPTION OF QUALITY OF LIFE WITHOUT THE RISK OF INJURY. THIS INTERVENTION ALSO SEEMED TO BE EFFECTIVE IN REDUCING THE NUMBER OF BLEEDINGS, REFERRALS TO THE HAEMOPHILIA CLINIC, AND ABSENCES FROM SCHOOL.	2015