1 2079 132 THE EFFECT OF EXERCISE, YOGA AND PHYSIOTHERAPY ON THE QUALITY OF LIFE OF PEOPLE WITH MULTIPLE SCLEROSIS: SYSTEMATIC REVIEW AND META-ANALYSIS. INTRODUCTION: MULTIPLE SCLEROSIS (MS) IS A CHRONIC AUTOIMMUNE DISEASE AFFECTING THE MYELINATED AXONS OF THE CENTRAL NERVOUS SYSTEM CAUSING NEUROLOGICAL DETERIORATION. PEOPLE LIVING WITH MS HAVE A POOR QUALITY OF LIFE (QOL) BECAUSE OF THE SYMPTOMS CAUSED BY THE DISEASE AND THERE ARE VARIOUS TYPES OF TREATMENTS TO MANAGE THE SYMPTOMS ASIDE FROM MEDICATION. OBJECTIVE: THIS META-ANALYSIS EXAMINES THE EFFECT OF EXERCISE, YOGA AND PHYSIOTHERAPY ON THE PHYSICAL, MENTAL AND SOCIAL QOL AMONG INDIVIDUALS LIVING WITH MS. SETTING: A SYSTEMATIC REVIEW WITH META-ANALYSIS WAS CONDUCTED USING PUBMED, MEDLINE, AND SCOPUS FROM 1990 TO 2017. THE STANDARD MEAN DIFFERENCE SCORES WERE COMPUTED IN EACH STUDY FOR THE DOMAINS OF PHYSICAL, MENTAL AND SOCIAL FUNCTIONING. RESULTS: EIGHTEEN STUDIES MET THE INCLUSION CRITERIA FOR THIS META-ANALYSIS. AEROBIC EXERCISE WAS EFFECTIVE IN IMPROVING SATISFACTION WITH PHYSICAL FUNCTIONING,D = 0.35 (95% CI = 0.08 TO 0.62), MENTAL FUNCTIONING D = 0.42 (95% CI = 0.11 TO 0.72), AND SOCIAL FUNCTIONING D = 0.42 (95% CI = 0.15 TO 0.69). PHYSIOTHERAPY WAS ALSO FOUND TO BE EFFECTIVE FOR PHYSICAL FUNCTIONING D = 0.50 (95% CI 0.19 TO 0.80), MENTAL FUNCTIONING D = 0.44 (95% CI 0.14 TO 0.75) AND SOCIAL FUNCTIONING D = 0.60 (95% CI 0.21 TO 0.90). HOWEVER YOGA AND COMBINATION OF EXERCISES DID NOT HAVE A SIGNIFICANT EFFECT ON ANY OF THE QOL DOMAINS. CONCLUSION: THESE FINDINGS SUGGEST THAT AEROBIC EXERCISE AND PHYSIOTHERAPY IMPROVES THE SATISFACTION OF MS PATIENTS WITH THEIR PHYSICAL, MENTAL AND SOCIAL FUNCTIONING AND MAY BE INCLUDED AS NORMAL PRACTICE IN THE TREATMENT OF MS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
2 1740  46 PHYSICAL AND PSYCHOSOCIAL BENEFITS OF YOGA IN CANCER PATIENTS AND SURVIVORS, A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: THIS STUDY AIMED TO SYSTEMATICALLY REVIEW THE EVIDENCE FROM RANDOMIZED CONTROLLED TRIALS (RCTS) AND TO CONDUCT A META-ANALYSIS OF THE EFFECTS OF YOGA ON PHYSICAL AND PSYCHOSOCIAL OUTCOMES IN CANCER PATIENTS AND SURVIVORS. METHODS: A SYSTEMATIC LITERATURE SEARCH IN TEN DATABASES WAS CONDUCTED IN NOVEMBER 2011. STUDIES WERE INCLUDED IF THEY HAD AN RCT DESIGN, FOCUSED ON CANCER PATIENTS OR SURVIVORS, INCLUDED PHYSICAL POSTURES IN THE YOGA PROGRAM, COMPARED YOGA WITH A NON-EXERCISE OR WAITLIST CONTROL GROUP, AND EVALUATED PHYSICAL AND/OR PSYCHOSOCIAL OUTCOMES. TWO RESEARCHERS INDEPENDENTLY RATED THE QUALITY OF THE INCLUDED RCTS, AND HIGH QUALITY WAS DEFINED AS >50% OF THE TOTAL POSSIBLE SCORE. EFFECT SIZES (COHEN'S D) WERE CALCULATED FOR OUTCOMES STUDIED IN MORE THAN THREE STUDIES AMONG PATIENTS WITH BREAST CANCER USING MEANS AND STANDARD DEVIATIONS OF POST-TEST SCORES OF THE INTERVENTION AND CONTROL GROUPS. RESULTS: SIXTEEN PUBLICATIONS OF 13 RCTS MET THE INCLUSION CRITERIA, OF WHICH ONE INCLUDED PATIENTS WITH LYMPHOMAS AND THE OTHERS FOCUSED ON PATIENTS WITH BREAST CANCER. THE MEDIAN QUALITY SCORE WAS 67% (RANGE: 22-89%). THE INCLUDED STUDIES EVALUATED 23 PHYSICAL AND 20 PSYCHOSOCIAL OUTCOMES. OF THE OUTCOMES STUDIED IN MORE THAN THREE STUDIES AMONG PATIENTS WITH BREAST CANCER, WE FOUND LARGE REDUCTIONS IN DISTRESS, ANXIETY, AND DEPRESSION (D = -0.69 TO -0.75), MODERATE REDUCTIONS IN FATIGUE (D = -0.51), MODERATE INCREASES IN GENERAL QUALITY OF LIFE, EMOTIONAL FUNCTION AND SOCIAL FUNCTION (D = 0.33 TO 0.49), AND A SMALL INCREASE IN FUNCTIONAL WELL-BEING (D = 0.31). EFFECTS ON PHYSICAL FUNCTION AND SLEEP WERE SMALL AND NOT SIGNIFICANT. CONCLUSION: YOGA APPEARED TO BE A FEASIBLE INTERVENTION AND BENEFICIAL EFFECTS ON SEVERAL PHYSICAL AND PSYCHOSOCIAL SYMPTOMS WERE REPORTED. IN PATIENTS WITH BREAST CANCER, EFFECT SIZE ON FUNCTIONAL WELL-BEING WAS SMALL, AND THEY WERE MODERATE TO LARGE FOR PSYCHOSOCIAL OUTCOMES.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
3 1299  49 HATHA YOGA FOR ACUTE, CHRONIC AND/OR TREATMENT-RESISTANT MOOD AND ANXIETY DISORDERS: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: THE AIM OF THIS STUDY WAS TO SYSTEMATICALLY INVESTIGATE THE EFFECTIVENESS OF HATHA YOGA IN TREATING ACUTE, CHRONIC AND/OR TREATMENT-RESISTANT MOOD AND ANXIETY DISORDERS. METHODS: MEDLINE, COCHRANE LIBRARY, CURRENT CONTROLLED TRIALS, CLINICAL TRIALS.GOV, NHR CENTRE FOR REVIEWS AND DISSEMINATION, PSYCINFO AND CINAHL WERE SEARCHED THROUGH JUNE 2018. RANDOMIZED CONTROLLED TRIALS WITH PATIENTS WITH MOOD AND ANXIETY DISORDERS WERE INCLUDED. MAIN OUTCOMES WERE CONTINUOUS MEASURES OF SEVERITY OF MOOD AND ANXIETY SYMPTOMS. COHEN'S D WAS CALCULATED AS A MEASURE OF EFFECT SIZE. META-ANALYSES USING A RANDOM EFFECTS MODEL WAS APPLIED TO ESTIMATE DIRECT COMPARISONS BETWEEN YOGA AND CONTROL CONDITIONS FOR DEPRESSION AND ANXIETY OUTCOMES. PUBLICATION BIAS WAS VISUALLY INSPECTED USING FUNNEL PLOTS. RESULTS: EIGHTEEN STUDIES WERE FOUND, FOURTEEN IN ACUTE PATIENTS AND FOUR IN CHRONIC PATIENTS. MOST STUDIES WERE OF LOW QUALITY. FOR DEPRESSION OUTCOMES, HATHA YOGA DID NOT SHOW A SIGNIFICANT EFFECT WHEN COMPARED TO TREATMENT AS USUAL, AN OVERALL EFFECT SIZE OF COHEN'S D -0.64 (95% CI = -1.41, 0.13) OR TO ALL ACTIVE CONTROL GROUPS, COHEN'S D -0.13 (95% CI = -0.49, 0.22). A SUB-ANALYSIS SHOWED THAT YOGA HAD A SIGNIFICANT EFFECT ON THE REDUCTION OF DEPRESSION COMPARED TO PSYCHOEDUCATION CONTROL GROUPS, COHEN'S D -0.52 (95% CI = -0.96, -0.08) BUT NOT TO OTHER ACTIVE CONTROL GROUPS, COHEN'S D 0.28 (95% CI = -0.07, 0.63) FOR STUDIES USING A FOLLOW-UP OF SIX MONTHS OR MORE, HATHA YOGA HAD NO EFFECT ON THE REDUCTION OF DEPRESSION COMPARED TO ACTIVE CONTROL GROUPS, COHEN'S D -0.14 (95% CI = -0.60, 0.33). REGARDING ANXIETY, HATHA YOGA HAD NO SIGNIFICANT EFFECT WHEN COMPARED TO ACTIVE CONTROL GROUPS, COHEN'S D -0.09 (95% CI = -0.47, 0.30). THE I2 AND Q-STATISTIC REVEALED HETEROGENEITY AMONGST COMPARISONS. QUALITATIVE ANALYSES SUGGEST SOME PROMISE OF HATHA YOGA FOR CHRONIC POPULATIONS. CONCLUSIONS: THE ABILITY TO DRAW FIRM CONCLUSIONS IS LIMITED BY THE NOTABLE HETEROGENEITY AND LOW QUALITY OF MOST OF THE INCLUDED STUDIES. WITH THIS CAVEAT IN MIND, THE RESULTS OF THE CURRENT META-ANALYSIS SUGGEST THAT HATHA YOGA DOES NOT HAVE EFFECTS ON ACUTE, CHRONIC AND/OR TREATMENT-RESISTANT MOOD AND ANXIETY DISORDERS COMPARED TO TREATMENT AS USUAL OR ACTIVE CONTROL GROUPS. HOWEVER, WHEN COMPARED TO PSYCHOEDUCATION, HATHA YOGA SHOWED MORE REDUCTIONS IN DEPRESSION. IT IS CLEAR THAT MORE HIGH-QUALITY STUDIES ARE NEEDED TO ADVANCE THE FIELD.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                            
4 2683  46 YOGA IN THE MANAGEMENT OF CHRONIC DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: HEART DISEASE, STROKE, AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) ARE THE LEADING CAUSES OF DEATH AND DISABILITY WORLDWIDE. ALTHOUGH INDIVIDUALS WITH THESE CONDITIONS HAVE BEEN REPORTED TO BENEFIT FROM YOGA, ITS EFFECTIVENESS REMAINS UNCLEAR. OBJECTIVE: TO PERFORM A SYSTEMATIC REVIEW OF THE EFFECTIVENESS OF YOGA ON EXERCISE CAPACITY, HEALTH RELATED QUALITY OF LIFE (HRQL), AND PSYCHOLOGICAL WELL-BEING FOR INDIVIDUALS WITH CHRONIC DISEASE AND DESCRIBE THE STRUCTURE AND DELIVERY OF PROGRAMS. RESEARCH DESIGN: WE PERFORMED A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS EXAMINING YOGA PROGRAMS FOR INDIVIDUALS WITH HEART DISEASE, STROKE, AND COPD COMPARED WITH USUAL CARE. QUALITY WAS ASSESSED USING THE COCHRANE RISK OF BIAS TOOL. META-ANALYSES WERE CONDUCTED USING REVIEW MANAGER 5.3. THE PROTOCOL WAS REGISTERED ON PROSPERO (CRD42014014589). RESULTS: TEN STUDIES (431 INDIVIDUALS, MEAN AGE 56+/-8 Y) WERE INCLUDED AND WERE COMPARABLE IN THEIR DESIGN AND COMPONENTS, IRRESPECTIVE OF THE CHRONIC DISEASE. THE STANDARDIZED MEAN DIFFERENCE FOR THE MEAN CHANGE IN EXERCISE CAPACITY WAS 2.69 (95% CONFIDENCE INTERVAL, 1.39-3.99) AND FOR HRQL IT WAS 1.24 (95% CONFIDENCE INTERVAL, -0.37 TO 2.85). SYMPTOMS OF ANXIETY WERE REDUCED AFTER YOGA IN INDIVIDUALS WITH STROKE, ALTHOUGH THIS WAS NOT OBSERVED IN INDIVIDUALS WITH COPD. THE EFFECT OF YOGA ON SYMPTOMS OF DEPRESSION VARIED ACROSS STUDIES WITH NO SIGNIFICANT EFFECTS COMPARED WITH USUAL CARE. CONCLUSIONS: YOGA PROGRAMS HAVE SIMILAR DESIGNS AND COMPONENTS ACROSS CHRONIC DISEASE POPULATIONS. COMPARED WITH USUAL CARE, YOGA RESULTED IN SIGNIFICANT IMPROVEMENTS IN EXERCISE CAPACITY AND A MEAN IMPROVEMENT IN HRQL. YOGA PROGRAMS MAY BE A USEFUL ADJUNCT TO FORMAL REHABILITATION PROGRAMS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
5 1043  36 EFFECTS OF YOGA INTERVENTIONS ON FATIGUE: A META-ANALYSIS. BACKGROUND. RESEARCHERS AIMED AT SYSTEMATICALLY REVIEWING AND META-ANALYZING THE EFFECTIVENESS OF YOGA INTERVENTIONS FOR FATIGUE. METHODS. PUBMED/MEDLINE WAS SEARCHED UNTIL JANUARY 2012 FOR CONTROLLED CLINICAL STUDIES. TWO REVIEWERS INDEPENDENTLY EXTRACTED THE DATA. THE METHODOLOGICAL QUALITY OF THE STUDIES WAS ASSESSED. A META-ANALYSIS WAS PERFORMED. RESULTS. NINETEEN CLINICAL STUDIES (TOTAL N = 948) WERE INCLUDED IN THIS REVIEW. INVESTIGATED YOGA STYLES INCLUDED HATHA, IYENGAR, ASANAS, PATANJALI, SAHAJA, AND TIBETAN YOGA. PARTICIPANTS WERE SUFFERING FROM CANCER, MULTIPLE SCLEROSIS, DIALYSIS, CHRONIC PANCREATITIS, FIBROMYALGIA, ASTHMA, OR WERE HEALTHY. YOGA HAD A SMALL POSITIVE EFFECT ON FATIGUE (SMD = 0.27, 59% CI = 0.23-0.31). SEVEN STUDIES RECEIVED 4 POINTS ON THE JADAD SCORE. THERE WERE BASELINE DIFFERENCES IN AT LEAST 5 STUDIES. CONCLUSION. OVERALL, THE EFFECTS OF YOGA INTERVENTIONS ON FATIGUE WERE ONLY SMALL, PARTICULARLY IN CANCER PATIENTS. ALTHOUGH YOGA IS GENERALLY A SAFE THERAPEUTIC INTERVENTION AND EFFECTIVE TO ATTENUATE OTHER HEALTH-RELATED SYMPTOMS, THIS META-ANALYSIS WAS NOT ABLE TO DEFINE THE POWERFUL EFFECT OF YOGA ON PATIENTS SUFFERING FROM FATIGUE. TREATMENT EFFECTS OF YOGA COULD BE IMPROVED IN WELL-DESIGNED FUTURE STUDIES. ACCORDING TO THE GRADE RECOMMENDATIONS ASSESSING THE OVERALL QUALITY OF EVIDENCE, THERE IS A MODERATE EFFECT OF THE CONFIDENCE PLACED IN THE ESTIMATES OF THE EFFECTS DISCUSSED HERE.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
6 2540  45 YOGA FOR ANXIETY: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. YOGA HAS BECOME A POPULAR APPROACH TO IMPROVE EMOTIONAL HEALTH. THE AIM OF THIS REVIEW WAS TO SYSTEMATICALLY ASSESS AND META-ANALYZE THE EFFECTIVENESS AND SAFETY OF YOGA FOR ANXIETY. MEDLINE/PUBMED, SCOPUS, THE COCHRANE LIBRARY, PSYCINFO, AND INDMED WERE SEARCHED THROUGH OCTOBER 2016 FOR RANDOMIZED CONTROLLED TRIALS (RCTS) OF YOGA FOR INDIVIDUALS WITH ANXIETY DISORDERS OR ELEVATED LEVELS OF ANXIETY. THE PRIMARY OUTCOMES WERE ANXIETY AND REMISSION RATES, AND SECONDARY OUTCOMES WERE DEPRESSION, QUALITY OF LIFE, AND SAFETY. RISK OF BIAS WAS ASSESSED USING THE COCHRANE TOOL. EIGHT RCTS WITH 319 PARTICIPANTS (MEAN AGE: 30.0-38.5 YEARS) WERE INCLUDED. RISK OF SELECTION BIAS WAS UNCLEAR FOR MOST RCTS. META-ANALYSES REVEALED EVIDENCE FOR SMALL SHORT-TERM EFFECTS OF YOGA ON ANXIETY COMPARED TO NO TREATMENT (STANDARDIZED MEAN DIFFERENCE [SMD] = -0.43; 95% CONFIDENCE INTERVAL [CI] = -0.74, -0.11; P = .008), AND LARGE EFFECTS COMPARED TO ACTIVE COMPARATORS (SMD = -0.86; 95% CI = -1.56, -0.15; P = .02). SMALL EFFECTS ON DEPRESSION WERE FOUND COMPARED TO NO TREATMENT (SMD = -0.35; 95% CI = -0.66, -0.04; P = .03). EFFECTS WERE ROBUST AGAINST POTENTIAL METHODOLOGICAL BIAS. NO EFFECTS WERE FOUND FOR PATIENTS WITH ANXIETY DISORDERS DIAGNOSED BY DIAGNOSTIC AND STATISTICAL MANUAL CRITERIA, ONLY FOR PATIENTS DIAGNOSED BY OTHER METHODS, AND FOR INDIVIDUALS WITH ELEVATED LEVELS OF ANXIETY WITHOUT A FORMAL DIAGNOSIS. ONLY THREE RCTS REPORTED SAFETY-RELATED DATA BUT THESE INDICATED THAT YOGA WAS NOT ASSOCIATED WITH INCREASED INJURIES. IN CONCLUSION, YOGA MIGHT BE AN EFFECTIVE AND SAFE INTERVENTION FOR INDIVIDUALS WITH ELEVATED LEVELS OF ANXIETY. THERE WAS INCONCLUSIVE EVIDENCE FOR EFFECTS OF YOGA IN ANXIETY DISORDERS. MORE HIGH-QUALITY STUDIES ARE NEEDED AND ARE WARRANTED GIVEN THESE PRELIMINARY FINDINGS AND PLAUSIBLE MECHANISMS OF ACTION.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
7 2597  40 YOGA FOR MULTIPLE SCLEROSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. WHILE YOGA SEEMS TO BE EFFECTIVE IN A NUMBER OF NEUROPSYCHIATRIC DISORDERS, THE EVIDENCE OF EFFICACY IN MULTIPLE SCLEROSIS REMAINS UNCLEAR. THE AIM OF THIS REVIEW WAS TO SYSTEMATICALLY ASSESS AND META-ANALYZE THE AVAILABLE DATA ON EFFICACY AND SAFETY OF YOGA IN PATIENTS WITH MULTIPLE SCLEROSIS. MEDLINE/PUBMED, SCOPUS, THE COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS, PSYCINFO, CAM-QUEST, CAMBASE, AND INDMED WERE SEARCHED THROUGH MARCH 2014. RANDOMIZED CONTROLLED TRIALS (RCTS) OF YOGA FOR PATIENTS WITH MULTIPLE SCLEROSIS WERE INCLUDED IF THEY ASSESSED HEALTH-RELATED QUALITY OF LIFE, FATIGUE, AND/OR MOBILITY. MOOD, COGNITIVE FUNCTION, AND SAFETY WERE DEFINED AS SECONDARY OUTCOME MEASURES. RISK OF BIAS WAS ASSESSED USING THE COCHRANE TOOL. SEVEN RCTS WITH A TOTAL OF 670 PATIENTS WERE INCLUDED. EVIDENCE FOR SHORT-TERM EFFECTS OF YOGA COMPARED TO USUAL CARE WERE FOUND FOR FATIGUE (STANDARDIZED MEAN DIFFERENCE [SMD] = -0.52; 95% CONFIDENCE INTERVALS (CI) = -1.02 TO -0.02; P = 0.04; HETEROGENEITY: I2 = 60%; CHI2 = 7.43; P = 0.06) AND MOOD (SMD = -0.55; 95%CI = -0.96 TO -0.13; P = 0.01; HETEROGENEITY: I2 = 0%; CHI2 = 1.25; P = 0.53), BUT NOT FOR HEALTH-RELATED QUALITY OF LIFE, MUSCLE FUNCTION, OR COGNITIVE FUNCTION. THE EFFECTS ON FATIGUE AND MOOD WERE NOT ROBUST AGAINST BIAS. NO SHORT-TERM OR LONGER TERM EFFECTS OF YOGA COMPARED TO EXERCISE WERE FOUND. YOGA WAS NOT ASSOCIATED WITH SERIOUS ADVERSE EVENTS. IN CONCLUSION, SINCE NO METHODOLOGICAL SOUND EVIDENCE WAS FOUND, NO RECOMMENDATION CAN BE MADE REGARDING YOGA AS A ROUTINE INTERVENTION FOR PATIENTS WITH MULTIPLE SCLEROSIS. YOGA MIGHT BE CONSIDERED A TREATMENT OPTION FOR PATIENTS WHO ARE NOT ADHERENT TO RECOMMENDED EXERCISE REGIMENS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
8 1077  46 EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION AND QUALITY OF LIFE IN WOMEN WITH BREAST CANCER: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. OBJECTIVE: THE AIM OF THIS META-ANALYSIS WAS TO EVALUATE THE EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION AND QUALITY OF LIFE (QOL) IN WOMEN WITH BREAST CANCER. DESIGN: A SYSTEMATIC SEARCH OF PUBMED, EMBASE, THE COCHRANE LIBRARY, THE CHINESE BIOMEDICAL LITERATURE DATABASE, AND THE CHINESE DIGITAL JOURNALS FULL-TEXT DATABASE WAS CARRIED OUT. RANDOMIZED CONTROL TRIALS (RCTS) EXAMINING THE EFFECTS OF YOGA, VERSUS A CONTROL GROUP RECEIVING NO INTERVENTION, ON PSYCHOLOGIC FUNCTIONING AND QOL IN WOMEN WITH BREAST CANCER WERE INCLUDED. METHODOLOGICAL QUALITY OF INCLUDED RCTS WAS ASSESSED ACCORDING TO THE COCHRANE HANDBOOK FOR SYSTEMATIC REVIEWS OF INTERVENTIONS 5.0.1, AND DATA WERE ANALYZED USING THE COCHRANE COLLABORATION'S REVIEW MANAGER 5.1. RESULTS: SIX (6) STUDIES INVOLVING 382 PATIENTS WERE INCLUDED. THE META-ANALYSIS SHOWED THAT YOGA CAN IMPROVE QOL FOR WOMEN WITH BREAST CANCER. A STATISTICALLY SIGNIFICANT EFFECT FAVORING YOGA FOR THE OUTCOME OF QOL WAS FOUND (STANDARD MEAN DIFFERENCE=0.27, 95% CONFIDENCE INTERVAL [0.02, 0.52], P=0.03). ALTHOUGH THE EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION OUTCOMES--SUCH AS ANXIETY, DEPRESSION, DISTRESS AND SLEEP--WERE IN THE EXPECTED DIRECTION, THESE EFFECTS WERE NOT STATISTICALLY SIGNIFICANT (P>0.05). FATIGUE SHOWED NO SIGNIFICANT DIFFERENCE (P>0.05). CONCLUSIONS: THE PRESENT DATA PROVIDED LITTLE INDICATION OF HOW EFFECTIVE YOGA MIGHT BE WHEN THEY WERE APPLIED BY WOMEN WITH BREAST CANCER EXCEPT FOR MILDLY EFFECTIVE IN QOL IMPROVEMENT. THE FINDINGS WERE BASED ON A SMALL BODY OF EVIDENCE IN WHICH METHODOLOGICAL QUALITY WAS NOT HIGH. FURTHER WELL-DESIGNED RCTS WITH LARGE SAMPLE SIZE ARE NEEDED TO CLARIFY THE UTILITY OF YOGA PRACTICE FOR THIS POPULATION.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
9 2397  41 YOGA AND COGNITION: A META-ANALYSIS OF CHRONIC AND ACUTE EFFECTS. OBJECTIVES: TO REVIEW AND SYNTHESIZE THE EXISTING LITERATURE ON THE EFFECTS OF YOGA ON COGNITIVE FUNCTION BY DETERMINING EFFECT SIZES THAT COULD SERVE AS A PLATFORM TO DESIGN, CALCULATE STATISTICAL POWER, AND IMPLEMENT FUTURE STUDIES. METHODS: THROUGH ELECTRONIC DATABASES, WE IDENTIFIED ACUTE STUDIES AND RANDOMIZED CONTROLLED TRIALS (RCTS) OF YOGA THAT REPORTED COGNITIVE OUTCOMES. INCLUSION CRITERIA INCLUDED THE FOLLOWING: USE OF AN OBJECTIVE MEASURE OF COGNITION AND SUFFICIENT DATA REPORTED TO ESTIMATE AN EFFECT SIZE. THE META-ANALYSIS WAS CONDUCTED USING COMPREHENSIVE META-ANALYSIS SOFTWARE. A RANDOM-EFFECTS MODEL WAS USED TO CALCULATE THE OVERALL WEIGHTED EFFECT SIZES, EXPRESSED AS HEDGE G. RESULTS: FIFTEEN RCTS AND 7 ACUTE EXPOSURE STUDIES EXAMINED THE EFFECTS OF YOGA ON COGNITION. A MODERATE EFFECT (G = 0.33, STANDARD ERROR = 0.08, 95% CONFIDENCE INTERVAL = 0.18-0.48, P < .001) OF YOGA ON COGNITION WAS OBSERVED FOR RCTS, WITH THE STRONGEST EFFECT FOR ATTENTION AND PROCESSING SPEED (G = 0.29, P < .001), FOLLOWED BY EXECUTIVE FUNCTION (G = 0.27, P = .001) AND MEMORY (G = 0.18, P = .051). ACUTE STUDIES SHOWED A STRONGER OVERALL EFFECT OF YOGA ON COGNITION (G = 0.56, STANDARD ERROR = 0.11, 95% CONFIDENCE INTERVAL = 0.33-0.78, P < .001). THE EFFECT WAS STRONGEST FOR MEMORY (G = 0.78, P < .001), FOLLOWED BY ATTENTION AND PROCESSING SPEED MEASURES (G = 0.49, P < .001) AND EXECUTIVE FUNCTIONS (G = 0.39, P < .003). CONCLUSIONS: YOGA PRACTICE SEEMS TO BE ASSOCIATED WITH MODERATE IMPROVEMENTS IN COGNITIVE FUNCTION. ALTHOUGH THE STUDIES ARE LIMITED BY SAMPLE SIZE, HETEROGENEOUS POPULATION CHARACTERISTICS, VARIED DOSES OF YOGA INTERVENTIONS, AND A MYRIAD OF COGNITIVE TESTS, THESE FINDINGS WARRANT RIGOROUS SYSTEMATIC RCTS AND WELL-DESIGNED COUNTERBALANCED ACUTE STUDIES TO COMPREHENSIVELY EXPLORE YOGA AS A MEANS TO IMPROVE OR SUSTAIN COGNITIVE ABILITIES ACROSS THE LIFE SPAN.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
10 2165  51 THE EFFECTS OF YOGA COMPARED TO ACTIVE AND INACTIVE CONTROLS ON PHYSICAL FUNCTION AND HEALTH RELATED QUALITY OF LIFE IN OLDER ADULTS- SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED CONTROLLED TRIALS. BACKGROUND: YOGA HAS BEEN RECOMMENDED AS A MUSCLE STRENGTHENING AND BALANCE ACTIVITY IN NATIONAL AND GLOBAL PHYSICAL ACTIVITY GUIDELINES. HOWEVER, THE EVIDENCE BASE ESTABLISHING THE EFFECTIVENESS OF YOGA IN IMPROVING PHYSICAL FUNCTION AND HEALTH RELATED QUALITY OF LIFE (HRQOL) IN AN OLDER ADULT POPULATION NOT RECRUITED ON THE BASIS OF ANY SPECIFIC DISEASE OR CONDITION, HAS NOT BEEN SYSTEMATICALLY REVIEWED. THE OBJECTIVE OF THIS STUDY WAS TO SYNTHESISE EXISTING EVIDENCE ON THE EFFECTS OF YOGA ON PHYSICAL FUNCTION AND HRQOL IN OLDER ADULTS NOT CHARACTERISED BY ANY SPECIFIC CLINICAL CONDITION. METHODS: THE FOLLOWING DATABASES WERE SYSTEMATICALLY SEARCHED IN SEPTEMBER 2017: MEDLINE, PSYCINFO, CINAHL PLUS, SCOPUS, WEB OF SCIENCE, COCHRANE LIBRARY, EMBASE, SPORTDISCUS, AMED AND PROQUEST DISSERTATIONS & THESES GLOBAL. STUDY INCLUSION CRITERIA: OLDER ADULT PARTICIPANTS WITH MEAN AGE OF 60 YEARS AND ABOVE, NOT RECRUITED ON THE BASIS OF ANY SPECIFIC DISEASE OR CONDITION; YOGA INTERVENTION COMPARED WITH INACTIVE CONTROLS (EXAMPLE: WAIT-LIST CONTROL, EDUCATION BOOKLETS) OR ACTIVE CONTROLS (EXAMPLE: WALKING, CHAIR AEROBICS); PHYSICAL FUNCTION AND HRQOL OUTCOMES; AND RANDOMISED/CLUSTER RANDOMISED CONTROLLED TRIALS PUBLISHED IN ENGLISH. A VOTE COUNTING ANALYSIS AND META-ANALYSIS WITH STANDARDISED EFFECT SIZES (HEDGES' G) COMPUTED USING RANDOM EFFECTS MODELS WERE CONDUCTED. RESULTS: A TOTAL OF 27 RECORDS FROM 22 RCTS WERE INCLUDED (17 RCTS ASSESSED PHYSICAL FUNCTION AND 20 ASSESSED HRQOL). THE META-ANALYSIS REVEALED SIGNIFICANT EFFECTS (5% LEVEL OF SIGNIFICANCE) FAVOURING THE YOGA GROUP FOR THE FOLLOWING PHYSICAL FUNCTION OUTCOMES COMPARED WITH INACTIVE CONTROLS: BALANCE (EFFECT SIZE (ES) = 0.7), LOWER BODY FLEXIBILITY (ES = 0.5), LOWER LIMB STRENGTH (ES = 0.45); COMPARED WITH ACTIVE CONTROLS: LOWER LIMB STRENGTH (ES = 0.49), LOWER BODY FLEXIBILITY (ES = 0.28). FOR HRQOL, SIGNIFICANT EFFECTS FAVOURING YOGA WERE FOUND COMPARED TO INACTIVE CONTROLS FOR: DEPRESSION (ES = 0.64), PERCEIVED MENTAL HEALTH (ES = 0.6), PERCEIVED PHYSICAL HEALTH (ES = 0.61), SLEEP QUALITY (ES = 0.65), AND VITALITY (ES = 0.31); COMPARED TO ACTIVE CONTROLS: DEPRESSION (ES = 0.54). CONCLUSION: THIS REVIEW IS THE FIRST TO COMPARE THE EFFECTS OF YOGA WITH ACTIVE AND INACTIVE CONTROLS IN OLDER ADULTS NOT CHARACTERISED BY A SPECIFIC CLINICAL CONDITION. RESULTS INDICATE THAT YOGA INTERVENTIONS IMPROVE MULTIPLE PHYSICAL FUNCTION AND HRQOL OUTCOMES IN THIS POPULATION COMPARED TO BOTH CONTROL CONDITIONS. THIS STUDY PROVIDES ROBUST EVIDENCE FOR PROMOTING YOGA IN PHYSICAL ACTIVITY GUIDELINES FOR OLDER ADULTS AS A MULTIMODAL ACTIVITY THAT IMPROVES ASPECTS OF FITNESS LIKE STRENGTH, BALANCE AND FLEXIBILITY, AS WELL AS MENTAL WELLBEING. TRIAL REGISTRATION: PROSPERO REGISTRATION NUMBER: CRD42016038052 .	2019	

11 2110  46 THE EFFECT OF YOGA ON SLEEP QUALITY AND INSOMNIA IN WOMEN WITH SLEEP PROBLEMS: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: TO EXAMINE THE EFFECTIVENESS AND SAFETY OF YOGA OF WOMEN WITH SLEEP PROBLEMS BY PERFORMING A SYSTEMATIC REVIEW AND META-ANALYSIS. METHODS: MEDLINE/PUBMED, CLINICALKEY, SCIENCEDIRECT, EMBASE, PSYCINFO, AND THE COCHRANE LIBRARY WERE SEARCHED THROUGHOUT THE MONTH OF JUNE, 2019. RANDOMIZED CONTROLLED TRIALS COMPARING YOGA GROUPS WITH CONTROL GROUPS IN WOMEN WITH SLEEP PROBLEMS WERE INCLUDED. TWO REVIEWERS INDEPENDENTLY EVALUATED RISK OF BIAS BY USING THE RISK OF BIAS TOOL SUGGESTED BY THE COCHRANE COLLABORATION FOR PROGRAMMING AND CONDUCTING SYSTEMATIC REVIEWS AND META-ANALYSES. THE MAIN OUTCOME MEASURE WAS SLEEP QUALITY OR THE SEVERITY OF INSOMNIA, WHICH WAS MEASURED USING SUBJECTIVE INSTRUMENTS, SUCH AS THE PITTSBURGH SLEEP QUALITY INDEX (PSQI), INSOMNIA SEVERITY INDEX (ISI), OR OBJECTIVE INSTRUMENTS SUCH AS POLYSOMNOGRAPHY, ACTIGRAPHY, AND SAFETY OF THE INTERVENTION. FOR EACH OUTCOME, A STANDARDIZED MEAN DIFFERENCE (SMD) AND CONFIDENCE INTERVALS (CIS) OF 95% WERE DETERMINED. RESULTS: NINETEEN STUDIES IN THIS SYSTEMATIC REVIEW INCLUDED 1832 PARTICIPANTS. THE META-ANALYSIS OF THE COMBINED DATA CONDUCTED ACCORDING TO COMPREHENSIVE META-ANALYSIS SHOWED A SIGNIFICANT IMPROVEMENT IN SLEEP (SMD = - 0.327, 95% CI = - 0.506 TO - 0.148, P < 0.001). META-ANALYSES REVEALED POSITIVE EFFECTS OF YOGA USING PSQI SCORES IN 16 RANDOMIZED CONTROL TRIALS (RCTS), COMPARED WITH THE CONTROL GROUP IN IMPROVING SLEEP QUALITY AMONG WOMEN USING PSQI (SMD = - 0.54; 95% CI = - 0.89 TO - 0.19; P = 0.003). HOWEVER, THREE RCTS REVEALED NO EFFECTS OF YOGA COMPARED TO THE CONTROL GROUP IN REDUCING INSOMNIA AMONG WOMEN USING ISI (SMD = - 0.13; 95% CI = - 0.74 TO 0.48; P = 0.69). SEVEN RCTS REVEALED NO EVIDENCE FOR EFFECTS OF YOGA COMPARED WITH THE CONTROL GROUP IN IMPROVING SLEEP QUALITY FOR WOMEN WITH BREAST CANCER USING PSQI (SMD = - 0.15; 95% CI = - 0.31 TO 0.01; P = 0.5). FOUR RCTS REVEALED NO EVIDENCE FOR THE EFFECTS OF YOGA COMPARED WITH THE CONTROL GROUP IN IMPROVING THE SLEEP QUALITY FOR PERI/POSTMENOPAUSAL WOMEN USING PSQI (SMD = - 0.31; 95% CI = - 0.95 TO 0.33; P = 0.34). YOGA WAS NOT ASSOCIATED WITH ANY SERIOUS ADVERSE EVENTS. DISCUSSION: THIS SYSTEMATIC REVIEW AND META-ANALYSIS DEMONSTRATED THAT YOGA INTERVENTION IN WOMEN CAN BE BENEFICIAL WHEN COMPARED TO NON-ACTIVE CONTROL CONDITIONS IN TERM OF MANAGING SLEEP PROBLEMS. THE MODERATOR ANALYSES SUGGEST THAT PARTICIPANTS IN THE NON-BREAST CANCER SUBGROUP AND PARTICIPANTS IN THE NON-PERI/POSTMENOPAUSAL SUBGROUP WERE ASSOCIATED WITH GREATER BENEFITS, WITH A DIRECT CORRELATION OF TOTAL CLASS TIME WITH QUALITY OF SLEEP AMONG OTHER RELATED BENEFITS.	2020	
                                                                                                                                                                                                                                                           
12 1079  34 EFFECTS OF YOGA ON PSYCHOLOGICAL HEALTH, QUALITY OF LIFE, AND PHYSICAL HEALTH OF PATIENTS WITH CANCER: A META-ANALYSIS. YOGA IS ONE OF THE MOST WIDELY USED COMPLEMENTARY AND ALTERNATIVE MEDICINE THERAPIES TO MANAGE ILLNESS. THIS META-ANALYSIS AIMED TO DETERMINE THE EFFECTS OF YOGA ON PSYCHOLOGICAL HEALTH, QUALITY OF LIFE, AND PHYSICAL HEALTH OF PATIENTS WITH CANCER. STUDIES WERE IDENTIFIED THROUGH A SYSTEMATIC SEARCH OF SEVEN ELECTRONIC DATABASES AND WERE SELECTED IF THEY USED A RANDOMIZED CONTROLLED TRIAL DESIGN TO EXAMINE THE EFFECTS OF YOGA IN PATIENTS WITH CANCER. THE QUALITY OF EACH ARTICLE WAS RATED BY TWO OF THE AUTHORS USING THE PEDRO SCALE. TEN ARTICLES WERE SELECTED; THEIR PEDRO SCORES RANGED FROM 4 TO 7. THE YOGA GROUPS COMPARED TO WAITLIST CONTROL GROUPS OR SUPPORTIVE THERAPY GROUPS SHOWED SIGNIFICANTLY GREATER IMPROVEMENTS IN PSYCHOLOGICAL HEALTH: ANXIETY (P = .009), DEPRESSION (P = .002), DISTRESS (P = .003), AND STRESS (P = .006). HOWEVER, DUE TO THE MIXED AND LOW TO FAIR QUALITY AND SMALL NUMBER OF STUDIES CONDUCTED, THE FINDINGS ARE PRELIMINARY AND LIMITED AND SHOULD BE CONFIRMED THROUGH HIGHER-QUALITY, RANDOMIZED CONTROLLED TRIALS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
13  826  42 EFFECT OF YOGA ON HEALTH-RELATED QUALITY OF LIFE IN CENTRAL NERVOUS SYSTEM DISORDERS: A SYSTEMATIC REVIEW. OBJECTIVE: INVESTIGATE THE EFFECT OF YOGA ON HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN PATIENTS WITH CENTRAL NERVOUS SYSTEM DISORDERS. METHODS: A SYSTEMATIC SEARCH WAS CONDUCTED ON THE PUBMED-NCBI, EBSCO HOST, COCHRANE LIBRARY, SCOPUS AND SCIENCEDIRECT DATABASES UNTIL 05 APRIL 2021. ONLY RANDOMIZED CONTROL TRIALS PUBLISHED IN ENGLISH OR FRENCH WERE INCLUDED AND HAD TO COMPARE YOGA TO ANOTHER INTERVENTION GROUP OR A CONTROL GROUP. THEY ALSO HAD TO CLEARLY MEASURE HRQOL. METHODOLOGICAL QUALITY WAS ASSESSED WITH THE REVISED COCHRANE RISK-OF-BIAS TOOL FOR RANDOMIZED TRIALS AND THE QUALITY OF EVIDENCE WAS EVALUATED USING THE GRADING OF RECOMMENDATIONS ASSESSMENT, DEVELOPMENT AND EVALUATION (GRADE) CRITERIA. RESULTS: SIXTEEN STUDIES WERE FOUND, INCLUDING SIX FOR MULTIPLE SCLEROSIS, FIVE FOR PARKINSON'S DISEASE, TWO FOR STROKE, ONE FOR DEMENTIA, ONE FOR EPILEPSY AND ONE FOR BRAIN TUMOUR. ONLY 12 STUDIES PERFORMED BETWEEN-GROUP STATISTICS AND 8 FOUND A SIGNIFICANT DIFFERENCE BETWEEN GROUPS AFTER TREATMENT. WHEN YOGA WAS COMPARED TO NO INTERVENTION, THE RESULTS WERE GENERALLY IN FAVOUR OF THE YOGA GROUP, BUT WHEN YOGA WAS COMPARED TO ANOTHER INTERVENTION PROGRAMME, THERE WAS GENERALLY NO SIGNIFICANT DIFFERENCE BETWEEN GROUPS. THERE WERE MANY DIFFERENT HRQOL QUESTIONNAIRES, EVEN WITHIN THE SAME DISEASE, WHICH REDUCES THE COMPARABILITY OF STUDIES. CONCLUSIONS: WITH LOW TO MODERATE QUALITY OF THE EVIDENCE, YOGA SEEMS EFFECTIVE TO IMPROVE HRQOL IN PEOPLE WITH PARKINSON'S DISEASE. FOR MULTIPLE SCLEROSIS, STROKE, DEMENTIA, EPILEPSY AND BRAIN TUMOUR, THE QUALITY OF THE EVIDENCE IS STILL INSUFFICIENT TO CONCLUDE OF THE EFFECTIVENESS OF YOGA.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
14 2365  25 WALKING IS MORE EFFECTIVE THAN YOGA AT REDUCING SLEEP DISTURBANCE IN CANCER PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. THIS REVIEW AIMED TO DETERMINE WHETHER WALKING IS MORE EFFECTIVE THAN YOGA AT IMPROVING SLEEP DISTURBANCE IN CANCER PATIENTS. A SYSTEMATIC SEARCH OF RANDOMIZED CONTROLLED TRIALS WAS PERFORMED IN THE PUBMED, EMBASE, CINAHL, COCHRANE LIBRARY, CNKI, AIRITI LIBRARY, AND OTHER HEALTH-RELATED DATABASES. TWENTY-FIVE STUDIES WERE IDENTIFIED WITH A TOTAL OF 1918 PARTICIPANTS. THE PITTSBURGH SLEEP QUALITY INDEX WAS THE MOST COMMONLY USED OUTCOME MEASUREMENT TOOL, AND MODERATE-INTENSITY WALKING WAS THE MOST FREQUENTLY USED INTERVENTION. THE MAJORITY OF THE INCLUDED SUBJECTS WERE BREAST CANCER PATIENTS. OVERALL, WALKING SIGNIFICANTLY IMPROVED SLEEP DISTURBANCE COMPARED TO YOGA (P = 0.01). STATISTICALLY SIGNIFICANT MODERATORS INCLUDED ADHERENCE RATE FOR WALKING (P < 0.001) AND ALLOCATION CONCEALMENT AND OUTCOME MEASUREMENT TOOL FOR YOGA (P = 0.04; P = 0.03). WE CONCLUDED THAT WALKING IS MORE EFFECTIVE THAN YOGA IN IMPROVING SLEEP DISTURBANCE IN CANCER PATIENTS. THUS, MODERATE-INTENSITY WALKING IS RECOMMENDED FOR CANCER PATIENTS WITH SLEEP DISTURBANCE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
15 2607  46 YOGA FOR PRENATAL DEPRESSION: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: PRENATAL DEPRESSION CAN NEGATIVELY AFFECT THE PHYSICAL AND MENTAL HEALTH OF BOTH MOTHER AND FETUS. THE AIM OF THIS STUDY WAS TO DETERMINE THE EFFECTIVENESS OF YOGA AS AN INTERVENTION IN THE MANAGEMENT OF PRENATAL DEPRESSION. METHODS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS (RCTS) WAS CONDUCTED BY SEARCHING PUBMED, EMBASE, THE COCHRANE LIBRARY AND PSYCINFO FROM ALL RETRIEVED ARTICLES DESCRIBING SUCH TRIALS UP TO JULY 2014. RESULTS: SIX RCTS WERE IDENTIFIED IN THE SYSTEMATIC SEARCH. THE SAMPLE CONSISTED OF 375 PREGNANT WOMEN, MOST OF WHOM WERE BETWEEN 20 AND 40 YEARS OF AGE. THE DIAGNOSES OF DEPRESSION WERE DETERMINED BY THEIR SCORES ON STRUCTURED CLINICAL INTERVIEW FOR DSM-IV AND THE CENTER FOR EPIDEMIOLOGICAL STUDIES DEPRESSION SCALE. WHEN COMPARED WITH COMPARISON GROUPS (E.G., STANDARD PRENATAL CARE, STANDARD ANTENATAL EXERCISES, SOCIAL SUPPORT, ETC.), THE LEVEL OF DEPRESSION STATISTICALLY SIGNIFICANTLY REDUCED IN YOGA GROUPS (STANDARDIZED MEAN DIFFERENCE [SMD], -0.59; 95% CONFIDENCE INTERVAL [CI], -0.94 TO -0.25; P = 0.0007). ONE SUBGROUP ANALYSIS REVEALED THAT BOTH THE LEVELS OF DEPRESSIVE SYMPTOMS IN PRENATALLY DEPRESSED WOMEN (SMD, -0.46; CI, -0.90 TO -0.03; P = 0.04) AND NON-DEPRESSED WOMEN (SMD, -0.87; CI, -1.22 TO -0.52; P < 0.00001) WERE STATISTICALLY SIGNIFICANTLY LOWER IN YOGA GROUP THAN THAT IN CONTROL GROUP. THERE WERE TWO KINDS OF YOGA: THE PHYSICAL-EXERCISE-BASED YOGA AND INTEGRATED YOGA, WHICH, BESIDES PHYSICAL EXERCISES, INCLUDED PRANAYAMA, MEDITATION OR DEEP RELAXATION. THEREFORE, THE OTHER SUBGROUP ANALYSIS WAS CONDUCTED TO ESTIMATE EFFECTS OF THE TWO KINDS OF YOGA ON PRENATAL DEPRESSION. THE RESULTS SHOWED THAT THE LEVEL OF DEPRESSION WAS SIGNIFICANTLY DECREASED IN THE INTEGRATED YOGA GROUP (SMD, -0.79; CI, -1.07 TO -0.51; P < 0.00001) BUT NOT SIGNIFICANTLY REDUCED IN PHYSICAL-EXERCISE-BASED YOGA GROUP (SMD, -0.41; CI, -1.01 TO -0.18; P = 0.17). CONCLUSIONS: PRENATAL YOGA INTERVENTION IN PREGNANT WOMEN MAY BE EFFECTIVE IN PARTLY REDUCING DEPRESSIVE SYMPTOMS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
16 1044  31 EFFECTS OF YOGA INTERVENTIONS ON PAIN AND PAIN-ASSOCIATED DISABILITY: A META-ANALYSIS. UNLABELLED: WE SEARCHED DATABASES FOR CONTROLLED CLINICAL STUDIES, AND PERFORMED A META-ANALYSIS ON THE EFFECTIVENESS OF YOGA INTERVENTIONS ON PAIN AND ASSOCIATED DISABILITY. FIVE RANDOMIZED STUDIES REPORTED SINGLE-BLINDING AND HAD A HIGHER METHODOLOGICAL QUALITY; 7 STUDIES WERE RANDOMIZED BUT NOT BLINDED AND HAD MODERATE QUALITY; AND 4 NONRANDOMIZED STUDIES HAD LOW QUALITY. IN 6 STUDIES, YOGA WAS USED TO TREAT PATIENTS WITH BACK PAIN; IN 2 STUDIES TO TREAT RHEUMATOID ARTHRITIS; IN 2 STUDIES TO TREAT PATIENTS WITH HEADACHE/MIGRAINE; AND 6 STUDIES ENROLLED INDIVIDUALS FOR OTHER INDICATIONS. ALL STUDIES REPORTED POSITIVE EFFECTS IN FAVOR OF THE YOGA INTERVENTIONS. WITH RESPECT TO PAIN, A RANDOM EFFECT META-ANALYSIS ESTIMATED THE OVERALL TREATMENT EFFECT AT SMD = -.74 (CI: -.97; -.52, P < .0001), AND AN OVERALL TREATMENT EFFECT AT SMD = -.79 (CI: -1.02; -.56, P < .0001) FOR PAIN-RELATED DISABILITY. DESPITE SOME LIMITATIONS, THERE IS EVIDENCE THAT YOGA MAY BE USEFUL FOR SEVERAL PAIN-ASSOCIATED DISORDERS. MOREOVER, THERE ARE HINTS THAT EVEN SHORT-TERM INTERVENTIONS MIGHT BE EFFECTIVE. NEVERTHELESS, LARGE-SCALE FURTHER STUDIES HAVE TO IDENTIFY WHICH PATIENTS MAY BENEFIT FROM THE RESPECTIVE INTERVENTIONS. PERSPECTIVE: THIS META-ANALYSIS SUGGESTS THAT YOGA IS A USEFUL SUPPLEMENTARY APPROACH WITH MODERATE EFFECT SIZES ON PAIN AND ASSOCIATED DISABILITY.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
17  559  44 COULD YOGA PRACTICE IMPROVE TREATMENT-RELATED SIDE EFFECTS AND QUALITY OF LIFE FOR WOMEN WITH BREAST CANCER? A SYSTEMATIC REVIEW AND META-ANALYSIS. AIM: TO DETERMINE IF YOGA AS A COMPLEMENTARY AND ALTERNATIVE THERAPY WAS ASSOCIATED WITH ENHANCED HEALTH AND TREATMENT-RELATED SIDE EFFECTS IN PATIENTS WITH BREAST CANCER. THIS SYSTEMATIC REVIEW EXAMINES WHETHER YOGA PRACTICE PROVIDES ANY MEASURABLE BENEFIT, BOTH PHYSICALLY AND PSYCHOLOGICALLY, FOR WOMEN WITH BREAST CANCER. METHODS: PUBMED, EMBASE AND THE COCHRANE LIBRARY FOR RANDOMIZED CONTROLLED TRIALS (RCTS) THROUGHOUT JUNE 2013. WE EVALUATED THE QUALITY OF THE INCLUDED STUDIES BY THE COCHRANE HANDBOOK 5.2 STANDARDS AND ANALYZED THE DATA USING THE STATA SOFTWARE, VERSION 10.0. META-REGRESSION AND SUBGROUP ANALYSIS WERE ALSO PERFORMED TO IDENTIFY ADDITIONAL PREDICTORS OF OUTCOME AND TO ASSESS HETEROGENEITY. RESULTS: SIXTEEN RCTS WITH A TOTAL OF 930 PARTICIPANTS WERE INCLUDED. COMPARING YOGA GROUPS TO CONTROL GROUPS, THERE WAS A STATISTICALLY SIGNIFICANT DIFFERENCE IN OVERALL HEALTH-RELATED QUALITY OF LIFE, DEPRESSION, ANXIETY AND GASTROINTESTINAL SYMPTOMS. META-REGRESSION ANALYSES REVEALED THAT THE DURATION OF YOGA PRACTICE AND TYPE OF CONTROL GROUP PARTLY EXPLAINED THE HETEROGENEITY. SUBGROUP ANALYSES REVEALED THAT YOGA HAD A POSITIVE EFFECT ON ANXIETY ONLY WHEN IT HAD BEEN PRACTICED FOR LONGER THAN 3 MONTHS. ONLY THE WAIT-LIST CONTROL GROUP SHOWED AN EFFECT OF YOGA ON PHYSICAL WELL-BEING. CONCLUSION: THE CURRENT EVIDENCE DEMONSTRATES THAT YOGA PRACTICE COULD BE EFFECTIVE IN ENHANCING HEALTH AND MANAGING SOME TREATMENT-RELATED SIDE EFFECTS FOR PATIENTS RECOVERING FROM BREAST CANCER. IN FUTURE CLINICAL STUDIES, CLINICIANS SHOULD CONSIDER THE PATIENT'S WISHES ALONG WITH THE CURRENT BEST EVIDENCE OF THE EFFECTS OF YOGA PRACTICE IN THEIR CLINICAL DECISION-MAKING.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
18 2330  32 TWELVE WEEKS OF YOGA FOR CHRONIC NONSPECIFIC LOWER BACK PAIN: A META-ANALYSIS. OBJECTIVES: TO INVESTIGATE THE OVERALL EFFECTS OF 12 WEEKS OF YOGA PRACTICE ON CHRONIC NONSPECIFIC LOWER BACK PAIN. METHODS: PUBMED, EMBASE, PSYCINFO, WEB OF SCIENCE, AND THE COCHRANE LIBRARY DATABASES WERE SEARCHED FROM INCEPTION TO FEBRUARY 9, 2019, AND SIX RANDOMIZED CONTROLLED TRIALS WERE SELECTED FOR THIS META-ANALYSIS. RESULTS: THE POOLED FIXED-EFFECT SIZE OF SIX TRIALS SHOWED THAT 12 WEEKS OF YOGA PROGRAMS COULD SIGNIFICANTLY REDUCE CHRONIC NONSPECIFIC LOWER BACK PAIN BY 0.41 WITHIN THE TRIALS (STANDARDIZED MEAN DIFFERENCE; 95% CONFIDENCE INTERVAL: -0.58 TO -0.23; P < .0001). SUBGROUP ANALYSES ALSO SHOWED THAT SIGNIFICANT PAIN REDUCTION WAS RELATED TO TYPE OF YOGA, LENGTH OF SESSION, STUDY QUALITY, AND TIMING OF PAIN ASSESSMENT. CONCLUSIONS: THESE FINDINGS REVEAL THAT 12 WEEKS OF YOGA CAN HELP ALLEVIATE PAIN, AND YOGA PROGRAMS SHOULD TAKE INTO ACCOUNT THE SUBGROUP FACTORS TO INCREASE INDIVIDUALS' RELIEF FROM CHRONIC NONSPECIFIC LOWER BACK PAIN.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
19 1065  42 EFFECTS OF YOGA ON IMPROVING QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: COMPLICATIONS OF BREAST CANCER TREATMENT CAN CAUSE PHYSICAL AND PSYCHOSOCIAL DISTRESS IN PATIENTS. YOGA DEMONSTRATES SUBSTANTIAL POTENTIAL AS A SUPPORTIVE THERAPY FOR PATIENTS WITH BREAST CANCER. OUR AIM IS TO CONDUCT A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS TO EVALUATE THE EFFECTIVENESS OF YOGA IN ENHANCING THE QUALITY OF LIFE (QOL) OF PATIENTS WITH BREAST CANCER. METHODS: WE SEARCHED FOR STUDIES PUBLISHED BEFORE MARCH 2020 IN THE PUBMED, EMBASE, AND COCHRANE LIBRARY DATABASES. INDIVIDUAL EFFECT SIZES WERE STANDARDIZED, AND THE POOLED EFFECT SIZE WAS CALCULATED USING A RANDOM EFFECT MODEL. MEASURED OUTCOMES INCLUDED QOL, ANXIETY AND DEPRESSION, STRESS, FATIGUE, PAIN SEVERITY, AND SLEEP QUALITY. RESULTS: IN TOTAL, 26 TRIALS INVOLVING 2069 PATIENTS WERE REVIEWED. SIGNIFICANT ENHANCEMENT IN QOL WAS OBSERVED IMMEDIATELY AFTER THE YOGA INTERVENTION. THE POOLED MEAN DIFFERENCES IN SOCIAL (WEIGHTED MEAN DIFFERENCE [WMD]: 1.36, 95% CONFIDENCE INTERVAL [CI] 0.12-2.61), EMOTIONAL (WMD: 1.46, 95% CI 0.26-2.66), AND FUNCTIONAL WELL-BEING (WMD: 2.04, 95% CI 0.21-3.87) WERE SIGNIFICANTLY HIGHER IN THE YOGA GROUP THAN IN THE CONTROL GROUP. PATIENTS PRACTICING YOGA EXHIBITED SIGNIFICANT IMPROVEMENTS IN PHYSICAL WELL-BEING, MENTAL WELL-BEING, AND SLEEP QUALITY AS WELL AS REDUCTIONS IN ANXIETY, DEPRESSION, STRESS, FATIGUE, AND PAIN SEVERITY AFTER THE INTERVENTION. CONCLUSIONS: YOGA MAY ENHANCE QOL IN PATIENTS WITH BREAST CANCER EXPERIENCING POST-TREATMENT COMPLICATIONS. THEREFORE, WE RECOMMEND YOGA AS A SUPPORTIVE THERAPY FOR PATIENTS WITH BREAST CANCER TO RELIEVE POST-TREATMENT DISTRESS.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
20 1124  45 EFFICACY OF PRENATAL YOGA IN THE TREATMENT OF DEPRESSION AND ANXIETY DURING PREGNANCY: A SYSTEMATIC REVIEW AND META-ANALYSIS. WOMEN COMMONLY SUFFER FROM DEPRESSION DURING PREGNANCY. FOR REDUCING DEPRESSION, YOGA SEEMS TO BE MORE SUITABLE FOR PREGNANT WOMEN THAN OTHER PHYSICAL ACTIVITIES BECAUSE OF ITS LOW EXERCISE INTENSITY. THE OBJECTIVE OF THIS STUDY WAS TO ASSESS THE EFFICACY OF PRENATAL YOGA ON THE TREATMENT OF DEPRESSION DURING PREGNANCY. THREE ELECTRONIC DATABASES WERE SEARCHED FOR RELEVANT ARTICLES FROM THEIR INCEPTION TO MAY 2021, INCLUDING PUBMED, COCHRANE LIBRARY, AND SCIENCEDIRECT. PRE- AND POST-TEST OUTCOMES WERE ADOPTED TO ESTIMATE STANDARDIZED MEAN DIFFERENCE WITH A 95% CONFIDENCE INTERVAL FOR ASSESSING THE EFFICACY OF YOGA. HETEROGENEITY AMONG ARTICLES WAS DETECTED USING I(2) VALUE. A TOTAL OF 13 ARTICLES THAT CONTAINED 379 SUBJECTS WERE INCLUDED FOR META-ANALYSIS. NO SIGNIFICANT IMPROVEMENT IN DEPRESSION SCORES AFTER PRACTICING YOGA WAS OBSERVED FOR WOMEN WITHOUT DEPRESSION (P = 0.09) BUT SIGNIFICANT IMPROVEMENT WAS OBSERVED FOR WOMEN WITH DEPRESSION (P = 0.001). ALTHOUGH SIGNIFICANT IMPROVEMENT IN ANXIETY SCORES AFTER YOGA WAS OBSERVED FOR WOMEN WITHOUT DEPRESSION (P = 0.02), THE RESULTS OF THE SENSITIVITY ANALYSIS WERE NOT CONSISTENT, WHILE SIGNIFICANT IMPROVEMENT IN ANXIETY SCORES AFTER YOGA WAS ALSO OBSERVED FOR WOMEN WITH DEPRESSION (P &LT; 0.00001). THE CURRENT EVIDENCE HAS SUGGESTED THAT YOGA HAD SIGNIFICANT IMPROVEMENT IN DEPRESSION AND ANXIETY SCORES IN PREGNANT WOMEN WITH DEPRESSION. HOWEVER, THE LEVEL OF EVIDENCE OF THIS STUDY WAS NOT HIGH. MORE ARTICLES WITH HIGH LEVELS OF EVIDENCE SHOULD BE CONDUCTED TO CONFIRM OUR CONCLUSION IN THE FUTURE.	2022