1 1783 131 PREDICTORS OF HEALTH-RELATED QUALITY OF LIFE IN INDIANS WITH METABOLIC SYNDROME UNDERGOING RANDOMIZED CONTROLLED TRIAL OF YOGA-BASED LIFESTYLE INTERVENTION VS DIETARY INTERVENTION. THE PRESENT STUDY EXPLORES THE EFFICACY OF 12-WEEK YOGA + DIET-BASED LIFESTYLE INTERVENTION (YBLI) VS DIETARY INTERVENTION (DI) ON HEALTH-RELATED QUALITY OF LIFE (HRQOL) AND IDENTIFIES THE PREDICTORS OF CHANGE IN HRQOL IN INDIANS WITH METABOLIC SYNDROME (MET S). DATA FROM THE HISTORICAL RANDOMIZED CONTROLLED TRIAL WAS USED INCLUDING ADULTS (N = 260, 20-45 YEARS) WITH MET S. FOUR DOMAINS OF HRQOL WERE MEASURED AT BASELINE, 2 AND 12 WEEKS USING WHOQOL-BREF QUESTIONNAIRE. GENERALIZED ESTIMATING EQUATION AND CHI-SQUARE TEST WAS USED TO COMPARE 12-WEEK CHANGES IN HRQOL DOMAINS AND PROPORTION OF SUBJECTS, RESPECTIVELY. CHANGES IN HRQOL WERE PREDICTED USING REGRESSION MODELS CONCERNING CHANGES IN BODY MASS INDEX (BMI), PHYSICAL ACTIVITY, TOTAL CALORIE INTAKE, ADIPONECTIN, AND SUPEROXIDE DISMUTASE (SOD) LEVELS. EXPLORATORY MEDIATION ANALYSIS WAS CARRIED OUT USING BARON & KENNY APPROACH. YBLI RESULTED IN A SIGNIFICANTLY GREATER INCREASE IN THE PHYSICAL DOMAIN SCORE OF HRQOL THAN DI. A SIGNIFICANTLY GREATER PROPORTION OF SUBJECTS IN YBLI GROUP (71%) SHOWED AN INCREASE IN PHYSICAL DOMAIN SCORES COMPARED TO DI (51%). A UNIT CHANGE IN BMI NEGATIVELY PREDICTED A UNIT CHANGE IN PHYSICAL, PSYCHOLOGICAL AND ENVIRONMENTAL HEALTH. WHEREAS, A UNIT CHANGE IN ADIPONECTIN AND SOD LEVELS POSITIVELY PREDICTED A UNIT CHANGE IN PHYSICAL AND ENVIRONMENTAL HEALTH. PARTIAL MEDIATION BETWEEN YBLI INTERVENTION AND PHYSICAL HRQOL DOMAIN WAS OBSERVED VIA ADIPONECTIN. IN CONCLUSION, A 12-WEEK YBLI HAS A POSITIVE AND GREATER EFFECT ON HRQOL PHYSICAL DOMAIN SCORE THAN FOLLOWING DI ALONE. CHANGES IN BMI, ADIPONECTIN, AND SOD LEVELS MAY PREDICT CHANGES IN HRQOL DOMAINS AFTER LIFESTYLE INTERVENTION.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
2 1860  51 RANDOMIZED CONTROLLED TRIAL OF A 12-WEEK YOGA-BASED (INCLUDING DIET) LIFESTYLE VS. DIETARY INTERVENTION ON CARDIO-METABOLIC RISK FACTORS AND CONTINUOUS RISK SCORE IN INDIAN ADULTS WITH METABOLIC SYNDROME. METABOLIC SYNDROME, A PREDIABETIC AND PRECARDIOVASCULAR PATHOLOGIC CONDITION THAT BEGINS EARLY IN LIFE, TRACKS INTO ADULTHOOD AND MAGNIFIES WITH AGE. RANDOMIZED CONTROLLED TRIALS EVALUATING EFFICACY OF YOGA-BASED LIFESTYLE VS. DIETARY INTERVENTION ON METABOLIC SYNDROME ARE LACKING. HERE, THE EFFICACY OF A 12-WEEK YOGA-BASED LIFESTYLE INTERVENTION VS. DIETARY INTERVENTION ON CARDIO-METABOLIC RISK FACTORS AND METABOLIC SYNDROME RISK SCORES HAVE BEEN ASSESSED IN INDIAN ADULTS WITH METABOLIC SYNDROME. IN THIS TWO-ARM, OPEN LABEL, PARALLEL GROUP, RANDOMIZED CONTROLLED TRIAL, 260 ADULTS (20-45 YEARS) DIAGNOSED WITH METABOLIC SYNDROME AS PER JOINT INTERIM STATEMENT, 2009 WERE RANDOMIZED TO YOGA-BASED (INCLUDING DIET) LIFESTYLE OR DIETARY INTERVENTION ALONE (N = 130, EACH) FOR 12 WEEKS. PRIMARY ENDPOINTS WERE THE 12-WEEK CHANGES IN CARDIO-METABOLIC RISK FACTORS AND METABOLIC RISK SCORES. THE SECONDARY ENDPOINTS WERE THE 12-WEEK CHANGES IN THE PROPORTION OF SUBJECTS RECOVERED FROM METABOLIC SYNDROME, DIETARY INTAKE, AND PHYSICAL ACTIVITY. INTENT-TO-TREAT ANALYSIS WAS PERFORMED INCLUDING ALL THE SUBJECTS WITH BASELINE DATA WITH IMPUTED MISSING DATA. TREATMENT X TIME INTERACTION SHOWED YOGA-BASED LIFESTYLE INTERVENTION HAD A GREATER TREATMENT EFFECT OVER DIETARY INTERVENTION BY SIGNIFICANTLY REDUCING WAIST CIRCUMFERENCE, CONTINUOUS METABOLIC SYNDROME Z-SCORE, AND DIETARY INTAKE/DAY WHILE SIGNIFICANTLY INCREASING PHYSICAL ACTIVITY. HIGH-DENSITY LIPOPROTEIN CHOLESTEROL SHOWED A SIGNIFICANTLY GREATER REDUCTION FOLLOWING DIETARY INTERVENTION THAN YOGA-BASED LIFESTYLE INTERVENTION. A SIGNIFICANTLY GREATER PROPORTION OF SUBJECTS RECOVERED FROM METABOLIC SYNDROME IN YOGA-BASED LIFESTYLE (45.4%) VS. DIETARY INTERVENTION GROUP (32.3%). A 12-WEEK YOGA-BASED LIFESTYLE INTERVENTION IS MORE EFFICACIOUS THAN USUAL DIETARY INTERVENTION IN IMPROVING CARDIO-METABOLIC RISK FACTOR AND METABOLIC RISK SCORE IN INDIAN ADULTS WITH METABOLIC SYNDROME.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                              
3 1102  37 EFFECTS OF YOGA TRAINING ON BODY COMPOSITION AND OXIDANT-ANTIOXIDANT STATUS AMONG HEALTHY MALE. BACKGROUND: THE STRESSFUL CONDITION MAY CAUSE OXIDATIVE STRESS, WHICH IS RESPONSIBLE FOR VARIOUS DISEASES. AIMS: THE PRESENT STUDY WAS DESIGNED TO FIND OUT WHETHER YOGA HAS IMPACT ON THE REDUCTION OF OXIDATIVE STRESS. METHODS: FOR THE PRESENT STUDY, 95 (N = 95) HEALTHY MALE VOLUNTEERS WITHIN THE AGE GROUP OF 18-24 YEARS WERE INCLUDED, 35 (N = 35) VOLUNTEERS WERE EXCLUDED. THE REMAINING 60 (N = 60) VOLUNTEERS WERE RANDOMLY DIVIDED INTO TWO GROUPS: (A) YOGA GROUP (N = 30) AND (B) CONTROL GROUP (N = 30). YOGA TRAINING WAS GIVEN FOR 60 MIN PER DAY, 6 DAYS PER WEEK FOR 12 WEEKS IN THE YOGA GROUP, WITH NO YOGA TRAINING IN CONTROL GROUP. ASSESSMENT OF BODY COMPOSITION AND OXIDANT-ANTIOXIDANT STATUS WERE PERFORMED IN BOTH THE GROUPS AT BASELINE, BEFORE YOGA TRAINING (0 WEEK) AND AFTER (12 WEEKS) OF THE TRAINING. RESULTS: SIGNIFICANT REDUCTION (P < 0.001) IN THE PERCENTAGE OF BODY FAT AND MALONDIALDEHYDE; SIGNIFICANT ELEVATION (P < 0.001) IN SUPEROXIDE DISMUTASE, CATALASE, REDUCED GLUTATHIONE AND ASCORBIC ACID LEVELS WERE NOTED IN THE YOGA GROUP AFTER 12 WEEKS WHEN COMPARED TO BASELINE DATA (0 WEEK). HOWEVER, THERE WAS NO SIGNIFICANT DIFFERENCE IN HEIGHT, WEIGHT, BODY MASS INDEX, BODY SURFACE AREA AND LEAN BODY MASS AMONG THE YOGA GROUP AFTER 12 WEEKS WHEN COMPARED TO BASELINE DATA. THESE CHANGES MIGHT BE DUE TO YOGA TRAINING. CONCLUSIONS: REGULAR YOGA PRACTICE REDUCES BODY FAT AND OXIDATIVE STRESS. YOGA TRAINING MAY BE HELPFUL TO REDUCE THE CHANCE OF OCCURRENCE OF VARIOUS DISEASES AND HELPS TO MAINTAIN NORMAL HEALTHY LIFESTYLE.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
4  674  47 EFFECT OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE IN OVERWEIGHT AND OBESE SUBJECTS. OBJECTIVE: TO STUDY THE EFFECT OF A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN OVERWEIGHT AND OBESE PERSONS. DESIGN AND SETTING: NONRANDOMIZED, SINGLE-ARM INTERVENTIONAL STUDY CONDUCTED FROM AUGUST 2012 TO MARCH 2015 AT INTEGRAL HEALTH CLINIC, DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA. PARTICIPANTS: OVERWEIGHT (BODY-MASS INDEX [BMI], 23-24.9 KG/M(2)) AND OBESE (BMI, >/=25 KG/M(2)) PERSONS (N = 279) AGED 20-60 YEARS. INTERVENTION: PRETESTED YOGA-BASED LIFESTYLE INTERVENTION, INCLUDING ASANAS (POSTURES), PRANAYAMA (BREATHING EXERCISES), RELAXATION TECHNIQUES, LECTURES, GROUP SUPPORT, NUTRITION AWARENESS PROGRAM, AND INDIVIDUALIZED ADVICE. OUTCOME MEASURES: PRIMARY OUTCOME MEASURE WAS HRQOL, MEASURED BY USING SHORT VERSION OF WORLD HEALTH ORGANIZATION QUALITY OF LIFE (WHOQOL-BREF) QUESTIONNAIRE. SECONDARY OUTCOME MEASURES WERE ANTHROPOMETRIC VARIABLES, SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, PULSE RATE, LIPID PROFILE, AND FASTING GLUCOSE. A SUBGROUP ANALYSIS ACCORDING TO SEX WAS ALSO PERFORMED. RESULTS: THE OVERALL QUALITY OF LIFE AND HEALTH IMPROVED AFTER SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION IN OVERWEIGHT AND OBESE PERSONS. PHYSICAL, PSYCHOLOGICAL AND ENVIRONMENTAL DOMAIN SCORES SIGNIFICANTLY INCREASED FROM BASELINE TO DAY 10, AND EFFICACY WAS NOTED IN BOTH MALE AND FEMALE SUBGROUPS. AFTER 10 DAYS OF INTERVENTION, THE FOLLOWING ALSO DECREASED SIGNIFICANTLY: BODY WEIGHT, BMI, TOTAL BODY FAT, WAIST AND HIP CIRCUMFERENCE, WAIST-TO-HIP RATIO, SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, TOTAL CHOLESTEROL, LOW-DENSITY LIPOPROTEIN, TRIGLYCERIDES, AND FASTING GLUCOSE. CONCLUSION: A SHORT-TERM YOGA-BASED LIFESTYLE INTERVENTION HAD A POSITIVE EFFECT ON HRQOL IN OVERWEIGHT AND OBESE PERSONS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
5 1902  33 RESTORATIVE YOGA IN ADULTS WITH METABOLIC SYNDROME: A RANDOMIZED, CONTROLLED PILOT TRIAL. BACKGROUND: METABOLIC SYNDROME INCREASES THE RISK OF DIABETES AND CARDIOVASCULAR DISEASE. YOGA IMPROVES SOME METABOLIC PARAMETERS, BUT IT HAS NOT BEEN STUDIED IN PERSONS WITH METABOLIC SYNDROME. WE CONDUCTED A RANDOMIZED CONTROLLED PILOT TRIAL TO DETERMINE WHETHER A RESTORATIVE YOGA INTERVENTION WAS FEASIBLE AND ACCEPTABLE IN UNDERACTIVE, OVERWEIGHT ADULTS WITH METABOLIC SYNDROME. METHODS: TWENTY SIX UNDERACTIVE, OVERWEIGHT ADULT MEN AND WOMEN WITH METABOLIC SYNDROME WERE RANDOMIZED TO ATTEND 15 YOGA SESSIONS OF 90 MINUTES EACH OVER 10 WEEKS OR TO A WAIT-LIST CONTROL GROUP. FEASIBILITY WAS MEASURED BY RECRUITMENT RATES, SUBJECT RETENTION, AND ADHERENCE. ACCEPTABILITY WAS ASSESSED BY INTERVIEW AND QUESTIONNAIRES. CHANGES IN METABOLIC OUTCOMES AND QUESTIONNAIRE MEASURES FROM BASELINE TO WEEK 10 WERE CALCULATED. RESULTS: A TOTAL OF 280 PEOPLE WERE SCREENED BY PHONE, AND 93 WITH HIGH LIKELIHOOD OF METABOLIC SYNDROME WERE INVITED TO A SCREENING VISIT. OF THE 68 WHO ATTENDED SCREENING VISITS, 26 (38%) WERE RANDOMIZED, AND 24 (92%) COMPLETED THE TRIAL. ATTENDANCE AT YOGA CLASSES AND ADHERENCE TO HOME PRACTICE EXCEEDED OUR GOALS. IN THE YOGA GROUP, ALL PARTICIPANTS GAVE THE STUDY THE HIGHEST POSSIBLE SATISFACTION RATING, AND THE MAJORITY (87%) FELT THAT THE YOGA POSES WERE EASY TO PERFORM. THERE WAS TREND TO REDUCED BLOOD PRESSURE (P = 0.07), A SIGNIFICANT INCREASE IN ENERGY LEVEL (P < 0.009), AND TRENDS TO IMPROVEMENT IN WELL-BEING (P < 0.12) AND STRESS (P < 0.22) IN THE YOGA VERSUS CONTROL GROUP. CONCLUSIONS: RESTORATIVE YOGA WAS A FEASIBLE AND ACCEPTABLE INTERVENTION IN OVERWEIGHT ADULTS WITH METABOLIC SYNDROME. THE EFFICACY OF YOGA FOR IMPROVING METABOLIC PARAMETERS IN THIS POPULATION SHOULD BE EXPLORED IN A LARGER RANDOMIZED CONTROLLED TRIAL.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
6 1402  41 IMPACT OF YOGA ON BLOOD PRESSURE AND QUALITY OF LIFE IN PATIENTS WITH HYPERTENSION - A CONTROLLED TRIAL IN PRIMARY CARE, MATCHED FOR SYSTOLIC BLOOD PRESSURE. BACKGROUND: MEDICAL TREATMENT OF HYPERTENSION IS NOT ALWAYS SUFFICIENT TO ACHIEVE BLOOD PRESSURE CONTROL. DESPITE THIS, PREVIOUS STUDIES ON SUPPLEMENTARY THERAPIES, SUCH AS YOGA, ARE RELATIVELY FEW. WE INVESTIGATED THE EFFECTS OF TWO YOGA INTERVENTIONS ON BLOOD PRESSURE AND QUALITY OF LIFE IN PATIENTS IN PRIMARY HEALTH CARE DIAGNOSED WITH HYPERTENSION. METHODS: ADULT PATIENTS (AGE 20-80 YEARS) WITH DIAGNOSED HYPERTENSION WERE IDENTIFIED BY AN ELECTRONIC CHART SEARCH AT A PRIMARY HEALTH CARE CENTER IN SOUTHERN SWEDEN. IN TOTAL, 83 SUBJECTS WITH BLOOD PRESSURE VALUES OF 120-179/</=109 MMHG AT BASELINE WERE ENROLLED. AT BASELINE, THE PATIENTS UNDERWENT STANDARDIZED BLOOD PRESSURE MEASUREMENT AT THE HEALTH CARE CENTER AND THEY COMPLETED A QUESTIONNAIRE ON SELF-RATED QUALITY OF LIFE (WHOQOL-BREF). THERE WERE THREE GROUPS: 1) YOGA CLASS WITH YOGA INSTRUCTOR (N = 28); 2) YOGA AT HOME (N = 28); AND 3) A CONTROL GROUP (N = 27). THE PARTICIPANTS WERE MATCHED AT THE GROUP LEVEL FOR SYSTOLIC BLOOD PRESSURE. AFTER 12 WEEKS OF INTERVENTION, THE ASSESSMENTS WERE PERFORMED AGAIN. AT BASELINE A MAJORITY OF THE PATIENTS (92%) WERE ON ANTIHYPERTENSIVE MEDICATION, AND THE PATIENTS WERE REQUESTED NOT TO CHANGE THEIR MEDICATION DURING THE STUDY. RESULTS: THE YOGA CLASS GROUP SHOWED NO IMPROVEMENT IN BLOOD PRESSURE OR SELF-RATED QUALITY OF LIFE, WHILE IN THE YOGA AT HOME GROUP THERE WAS A DECLINE IN DIASTOLIC BLOOD PRESSURE OF 4.4 MMHG (P < 0.05) COMPARED TO THE CONTROL GROUP. MOREOVER, THE YOGA AT HOME GROUP SHOWED SIGNIFICANT IMPROVEMENT IN SELF-RATED QUALITY OF LIFE COMPARED TO THE CONTROL GROUP (P < 0.05). CONCLUSIONS: A SHORT YOGA PROGRAM FOR THE PATIENT TO PRACTICE AT HOME SEEMS TO HAVE AN ANTIHYPERTENSIVE EFFECT, AS WELL AS A POSITIVE EFFECT ON SELF-RATED QUALITY OF LIFE COMPARED TO CONTROLS. THIS IMPLIES THAT SIMPLE YOGA EXERCISES MAY BE USEFUL AS A SUPPLEMENTARY BLOOD PRESSURE THERAPY IN ADDITION TO MEDICAL TREATMENT WHEN PRESCRIBED BY PRIMARY CARE PHYSICIANS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                               
7 2834  37 YOGA'S EFFECT ON INFLAMMATORY BIOMARKERS AND METABOLIC RISK FACTORS IN A HIGH RISK POPULATION - A CONTROLLED TRIAL IN PRIMARY CARE. BACKGROUND: YOGA CAN REDUCE BLOOD PRESSURE AND HAS ALSO BEEN SUGGESTED TO REDUCE INFLAMMATORY BIOMARKERS AND METABOLIC RISK FACTORS FOR CARDIOVASCULAR DISEASES (CVDS). WE AIMED TO ASSESS THE BENEFIT OF TWO YOGA INTERVENTIONS ON INFLAMMATORY BIOMARKERS AND METABOLIC RISK FACTORS IN A HIGH RISK POPULATION IN PRIMARY CARE. METHODS: ADULT PATIENTS FROM A HEALTH CARE CENTER IN SWEDEN, WITH DIAGNOSED HYPERTENSION, WERE INVITED TO UNDERGO A BASELINE CHECK AT THE HEALTH CARE CENTER. BASELINE CHECK INCLUDED STANDARDIZED BLOOD PRESSURE MEASUREMENT, BMI AND WEIGHT CIRCUMFERENCE MEASUREMENTS, BLOOD SAMPLING (HS-CRP, IL-6, FP-GLUCOSE, HBA1C, CHOLESTEROL, TG, LDL AND HDL) AND A QUESTIONNAIRE ON SELF-RATED QUALITY OF LIFE (WHOQOL-BREF). THERE WERE THREE GROUPS: 1) YOGA CLASS WITH YOGA INSTRUCTOR; 2) YOGA AT HOME; AND 3) A CONTROL GROUP. IN TOTAL, 83 PATIENTS WERE INCLUDED AND MATCHED AT THE GROUP LEVEL FOR SYSTOLIC BLOOD PRESSURE. A MAJORITY OF THE PATIENTS (92 %) WERE ON ANTIHYPERTENSIVE MEDICATION, WHICH THEY WERE REQUESTED NOT TO CHANGE DURING THE STUDY. AFTER 12 WEEKS OF INTERVENTION, THE ASSESSMENTS WERE PERFORMED AGAIN. RESULTS: WE RECORDED NO EVIDENCE THAT YOGA ALTERED INFLAMMATORY BIOMARKERS OR METABOLIC RISK FACTORS IN OUR STUDY POPULATION. A TOTAL OF 49 PARTICIPANTS (59 %) MET THE CRITERIA FOR METABOLIC SYNDROME. CONCLUSION: THE YOGA INTERVENTIONS PERFORMED IN OUR STUDY DID NOT AFFECT INFLAMMATORY BIOMARKERS OR METABOLIC RISK FACTORS ASSOCIATED WITH CVD IN THE STUDY POPULATION OF PRIMARY CARE PATIENTS WITH HYPERTENSION. FURTHER RANDOMIZED TRIALS ARE NEEDED TO ELUCIDATE THE EFFECTS OF YOGA ON CVD RISK FACTORS IN THIS PARTICULAR GROUP. TRAIL REGISTRATION: NCT01302535 , FEBRUARY 22, 2011.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
8  192  47 A RANDOMIZED TRIAL COMPARING EFFECT OF YOGA AND EXERCISES ON QUALITY OF LIFE IN AMONG NURSING POPULATION WITH CHRONIC LOW BACK PAIN. BACKGROUND: CHRONIC LOW BACK PAIN (CLBP) ADVERSELY AFFECTS QUALITY OF LIFE (QOL) IN NURSING PROFESSIONALS. INTEGRATED YOGA HAS A POSITIVE IMPACT ON CLBP. STUDIES ASSESSING THE EFFECTS OF YOGA ON CLBP IN NURSING POPULATION ARE LACKING. AIM: THIS STUDY WAS CONDUCTED TO EVALUATE THE EFFECTS OF INTEGRATED YOGA AND PHYSICAL EXERCISES ON QOL IN NURSES WITH CLBP. METHODS: A TOTAL OF 88 WOMEN NURSES FROM A TERTIARY CARE HOSPITAL OF SOUTH INDIA WERE RANDOMIZED INTO YOGA GROUP (N = 44; AGE - 31.45 +/- 3.47 YEARS) AND PHYSICAL EXERCISE GROUP (N = 44; AGE - 32.75 +/- 3.71 YEARS). YOGA GROUP WAS INTERVENED WITH INTEGRATED YOGA THERAPY MODULE PRACTICES, 1 H/DAY AND 5 DAYS A WEEK FOR 6 WEEKS. PHYSICAL EXERCISE GROUP PRACTICED A SET OF PHYSICAL EXERCISES FOR THE SAME DURATION. ALL PARTICIPANTS WERE ASSESSED AT BASELINE AND AFTER 6 WEEKS WITH THE WORLD HEALTH ORGANIZATION QUALITY OF LIFE-BRIEF (WHOQOL-BREF) QUESTIONNAIRE. RESULTS: DATA WERE ANALYZED BY PAIRED-SAMPLES T-TEST AND INDEPENDENT-SAMPLES T-TEST FOR WITHIN- AND BETWEEN-GROUP COMPARISONS, RESPECTIVELY, USING THE STATISTICAL PACKAGE FOR THE SOCIAL SCIENCES (SPSS). WITHIN-GROUP ANALYSIS FOR QOL REVEALED A SIGNIFICANT IMPROVEMENT IN PHYSICAL, PSYCHOLOGICAL, AND SOCIAL DOMAINS (EXCEPT ENVIRONMENTAL DOMAIN) IN BOTH GROUPS. BETWEEN-GROUP ANALYSIS SHOWED A HIGHER PERCENTAGE OF IMPROVEMENT IN YOGA AS COMPARED TO EXERCISE GROUP EXCEPT ENVIRONMENTAL DOMAIN. CONCLUSIONS: INTEGRATED YOGA WAS SHOWED IMPROVEMENTS IN PHYSICAL, PSYCHOLOGICAL, AND SOCIAL HEALTH DOMAINS OF QOL BETTER THAN PHYSICAL EXERCISES AMONG NURSING PROFESSIONALS WITH CLBP. THERE IS A NEED TO INCORPORATE YOGA AS LIFESTYLE INTERVENTION FOR NURSING PROFESSIONALS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
9  159  36 A RANDOMISED COMPARATIVE TRIAL OF YOGA AND RELAXATION TO REDUCE STRESS AND ANXIETY. OBJECTIVE: TO COMPARE YOGA AND RELAXATION AS TREATMENT MODALITIES AT 10 AND 16 WEEKS FROM STUDY BASELINE TO DETERMINE IF EITHER OF MODALITY REDUCES SUBJECT STRESS, ANXIETY, BLOOD PRESSURE AND IMPROVE QUALITY OF LIFE. DESIGN: A RANDOMISED COMPARATIVE TRIAL WAS UNDERTAKEN COMPARING YOGA WITH RELAXATION. PARTICIPANTS: ONE HUNDRED AND THIRTY-ONE SUBJECTS WITH MILD TO MODERATE LEVELS OF STRESS WERE RECRUITED FROM THE COMMUNITY IN SOUTH AUSTRALIA. INTERVENTIONS: TEN WEEKLY 1- H SESSIONS OF RELAXATION OR HATHA YOGA. MAIN OUTCOME MEASURES: CHANGES IN THE STATE TRAIT PERSONALITY INVENTORY SUB-SCALE ANXIETY, GENERAL HEALTH QUESTIONNAIRE AND THE SHORT FORM-36. RESULTS: FOLLOWING THE 10 WEEK INTERVENTION STRESS, ANXIETY AND QUALITY OF LIFE SCORES IMPROVED OVER TIME. YOGA WAS FOUND TO BE AS EFFECTIVE AS RELAXATION IN REDUCING STRESS, ANXIETY AND IMPROVING HEALTH STATUS ON SEVEN DOMAINS OF THE SF-36. YOGA WAS MORE EFFECTIVE THAN RELAXATION IN IMPROVING MENTAL HEALTH. AT THE END OF THE 6 WEEK FOLLOW-UP PERIOD THERE WERE NO DIFFERENCES BETWEEN GROUPS IN LEVELS OF STRESS, ANXIETY AND ON FIVE DOMAINS OF THE SF-36. VITALITY, SOCIAL FUNCTION AND MENTAL HEALTH SCORES ON THE SF-36 WERE HIGHER IN THE RELAXATION GROUP DURING THE FOLLOW-UP PERIOD. CONCLUSION: YOGA APPEARS TO PROVIDE A COMPARABLE IMPROVEMENT IN STRESS, ANXIETY AND HEALTH STATUS COMPARED TO RELAXATION.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
10  247  46 A YOGA INTERVENTION FOR TYPE 2 DIABETES RISK REDUCTION: A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: TYPE 2 DIABETES IS A MAJOR HEALTH PROBLEM IN MANY COUNTRIES INCLUDING INDIA. YOGA MAY BE AN EFFECTIVE TYPE 2 DIABETES PREVENTION STRATEGY IN INDIA, PARTICULARLY GIVEN ITS CULTURAL FAMILIARITY. METHODS: THIS WAS A PARALLEL, RANDOMIZED CONTROLLED PILOT STUDY TO COLLECT FEASIBILITY AND PRELIMINARY EFFICACY DATA ON YOGA FOR DIABETES RISK FACTORS AMONG PEOPLE AT HIGH RISK OF DIABETES. PRIMARY OUTCOMES INCLUDED: CHANGES IN BMI, WAIST CIRCUMFERENCE, FASTING BLOOD GLUCOSE, POSTPRANDIAL BLOOD GLUCOSE, INSULIN, INSULIN RESISTANCE, BLOOD PRESSURE, AND CHOLESTEROL. WE ALSO LOOKED AT MEASURES OF PSYCHOLOGICAL WELL-BEING INCLUDING CHANGES IN DEPRESSION, ANXIETY, POSITIVE AND NEGATIVE AFFECT AND PERCEIVED STRESS. FORTY-ONE PARTICIPANTS WITH ELEVATED FASTING BLOOD GLUCOSE IN BANGALORE, INDIA WERE RANDOMIZED TO EITHER YOGA (N = 21) OR A WALKING CONTROL (N = 20). PARTICIPANTS WERE ASKED TO EITHER ATTEND YOGA CLASSES OR COMPLETE MONITORED WALKING 3-6 DAYS PER WEEK FOR EIGHT WEEKS. RANDOMIZATION AND ALLOCATION WAS PERFORMED USING COMPUTER-GENERATED RANDOM NUMBERS AND GROUP ASSIGNMENTS DELIVERED IN SEALED, OPAQUE ENVELOPES GENERATED BY OFF-SITE STUDY STAFF. DATA WERE ANALYZED BASED ON INTENTION TO TREAT. RESULTS: THIS STUDY WAS FEASIBLE IN TERMS OF RECRUITMENT, RETENTION AND ADHERENCE. IN ADDITION, YOGA PARTICIPANTS HAD SIGNIFICANTLY GREATER REDUCTIONS IN WEIGHT, WAIST CIRCUMFERENCE AND BMI VERSUS CONTROL (WEIGHT -0.8 +/- 2.1 VS. 1.4 +/- 3.6, P = 0.02; WAIST CIRCUMFERENCE -4.2 +/- 4.8 VS. 0.7 +/- 4.2, P < 0.01; BMI -0.2 +/- 0.8 VS. 0.6 +/- 1.6, P = 0.05). THERE WERE NO BETWEEN GROUP DIFFERENCES IN FASTING BLOOD GLUCOSE, POSTPRANDIAL BLOOD GLUCOSE, INSULIN RESISTANCE OR ANY OTHER FACTORS RELATED TO DIABETES RISK OR PSYCHOLOGICAL WELL-BEING. THERE WERE SIGNIFICANT REDUCTIONS IN SYSTOLIC AND DIASTOLIC BLOOD PRESSURE, TOTAL CHOLESTEROL, ANXIETY, DEPRESSION, NEGATIVE AFFECT AND PERCEIVED STRESS IN BOTH THE YOGA INTERVENTION AND WALKING CONTROL OVER THE COURSE OF THE STUDY. CONCLUSION: AMONG INDIANS WITH ELEVATED FASTING BLOOD GLUCOSE, WE FOUND THAT PARTICIPATION IN AN 8-WEEK YOGA INTERVENTION WAS FEASIBLE AND RESULTED IN GREATER WEIGHT LOSS AND REDUCTION IN WAIST CIRCUMFERENCE WHEN COMPARED TO A WALKING CONTROL. YOGA OFFERS A PROMISING LIFESTYLE INTERVENTION FOR DECREASING WEIGHT-RELATED TYPE 2 DIABETES RISK FACTORS AND POTENTIALLY INCREASING PSYCHOLOGICAL WELL-BEING. TRIAL REGISTRATION: CLINICALTRIALS.GOV IDENTIFIED NCT00090506.	2014	

11 2691  34 YOGA IN WOMEN WITH ABDOMINAL OBESITYA RANDOMIZED CONTROLLED TRIAL. BACKGROUND: ABDOMINAL OBESITY IS A MAJOR RISK FACTOR FOR MORBIDITY AND MORTALITY. THE AIM OF THIS STUDY WAS TO INVESTIGATE THE EFFECT OF YOGA ON WAIST CIRCUMFERENCE AND OTHER ANTHROPOMETRIC AND SELF-REPORTED VARIABLES IN WOMEN WITH ABDOMINAL OBESITY. METHODS: 60 WOMEN WITH ABDOMINAL OBESITY (WAIST CIRCUMFERENCE >/= 88 CM; BODY-MASS INDEX [BMI] >/= 25) WERE RANDOMLY ALLOCATED IN A 2:1 RATIO TO EITHER A 12-WEEK YOGA INTERVENTION (N = 40) OR A WAITING LIST (N = 20). THE WAIST CIRCUMFERENCE WAS THE PRIMARY ENDPOINT. SECONDARY (EXPLORATORY) ENDPOINTS INCLUDED THE WAIST/HIP RATIO, BODY WEIGHT, BMI, BODY FAT PERCENTAGE, BODY MUSCLE MASS PERCENTAGE, BLOOD PRESSURE, HEALTH-RELATED QUALITY OF LIFE, SELF-ESTEEM, SUBJECTIVE STRESS, BODY AWARENESS, AND BODY RESPONSIVENESS, AND THE SAFETY OF THE INTERVENTION. THE PERSONS ASSESSING THE OUTCOMES WERE BLINDED TO THE GROUP TO WHICH THE PATIENTS BELONGED. RESULTS: THE PATIENTS IN THE YOGA GROUP PARTICIPATED IN A MEAN OF 30.2+/-9.2 (MAXIMUM, 42) HOURS OF SUPERVISED YOGA PRACTICE. THEIR ABDOMINAL CIRCUM - FERENCE WAS SIGNIFICANTLY REDUCED IN COMPARISON TO THE PARTICIPANTS ON THE WAITING LIST, WITH AN INTERGROUP DIFFERENCE OF -3.8 CM (95% CONFIDENCE INTERVAL [-6.1; -1,.5]; P = 0.001). THERE WERE FURTHER, MODERATE INTERGROUP DIFFERENCES IN THE WAIST/HIP RATIO, BODY WEIGHT, BMI, BODY FAT PERCENTAGE, BODY MUSCLE MASS PERCENTAGE, MENTAL AND PHYSICAL WELL-BEING, SELF-ESTEEM, SUBJECTIVE STRESS, BODY AWARENESS, AND TRUST IN BODILY SENSATIONS (ALL P<0.05). THERE WERE NO SERIOUS ADVERSE EVENTS. NONE OF THE PARTICIPANTS EMBARKED ON A LOW-CALORIE DIET WHILE PARTICIPATING IN THE STUDY. CONCLUSION: THE 12-WEEK YOGA INTERVENTION HAD MODERATELY STRONG POSITIVE EFFECTS ON ANTHROPOMETRIC AND SELF-REPORTED VARIABLES IN WOMEN WITH ABDOMINAL OBESITY. YOGA IS SAFE IN THIS POPULATION AND CAN BE RECOMMENDED AS A TECHNIQUE FOR COMBATING ABDOMINAL OBESITY IN WOMEN.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
12  428  30 CAN YOGA HAVE ANY EFFECT ON SHOULDER AND ARM PAIN AND QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER? A RANDOMIZED, CONTROLLED, SINGLE-BLIND TRIAL. OBJECTIVE: TO EXAMINE THE EFFECTS OF YOGA ON SHOULDER AND ARM PAIN, QUALITY OF LIFE (QOL), DEPRESSION, AND PHYSICAL PERFORMANCE IN PATIENTS WITH BREAST CANCER. METHODS: THIS PROSPECTIVE, RANDOMIZED STUDY INCLUDED 42 PATIENTS. THE PATIENTS IN GROUP 1 UNDERWENT A 10-WEEK HATHA YOGA EXERCISE PROGRAM. THE PATIENTS IN GROUP 2 WERE INCLUDED IN A 10-WEEK FOLLOW-UP PROGRAM. OUR PRIMARY ENDPOINT WAS ARM AND SHOULDER PAIN INTENSITY. RESULTS: THE GROUP RECEIVING YOGA SHOWED A SIGNIFICANT IMPROVEMENT IN THEIR PAIN SEVERITY FROM BASELINE TO POST-TREATMENT, AND THESE BENEFITS WERE MAINTAINED AT 2.5 MONTHS POST-TREATMENT. WHEN COMPARED TO THE CONTROL GROUP, THERE WERE NO STATISTICALLY SIGNIFICANT DIFFERENCES BETWEEN THE 2 GROUPS WITH RESPECT TO THE PARAMETERS ASSESSED AT THE END OF WEEK 10. CONCLUSION: YOGA WAS AN EFFECTIVE AND SAFE EXERCISE FOR ALLEVIATING SHOULDER AND ARM PAIN, WHICH IS A COMPLICATION WITH A HIGH PREVALENCE IN PATIENTS WITH BREAST CANCER.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
13 1041  39 EFFECTS OF YOGA INTERVENTION ON SLEEP AND QUALITY-OF-LIFE IN ELDERLY: A RANDOMIZED CONTROLLED TRIAL. CONTEXT: YOGA AS A LIFE-STYLE PRACTICE HAS DEMONSTRATED BENEFICIAL EFFECTS. THE ROLE OF YOGA IN THE ELDERLY FOR SUCH BENEFITS MERITS INVESTIGATION. AIMS: THE AIM OF THIS STUDY IS TO EXAMINE THE EFFECTS OF YOGA INTERVENTION ON QUALITY-OF-LIFE (QOL) AND SLEEP QUALITY IN THE ELDERLY LIVING IN OLD AGE HOMES. SETTINGS AND DESIGN: SINGLE BLIND CONTROLLED STUDY WITH BLOCK RANDOMIZATION OF ELDERLY HOMES. MATERIALS AND METHODS: A TOTAL OF 120 SUBJECTS FROM NINE ELDERLY HOMES WERE RANDOMIZED IN TO YOGA GROUP (N=62) AND WAITLIST GROUP (N=58). SUBJECTS IN THE YOGA GROUP WERE GIVEN YOGA INTERVENTION DAILY FOR 1 MONTH AND WEEKLY UNTIL 3 MONTHS AND WERE ENCOURAGED TO PRACTICE YOGA WITHOUT SUPERVISION UNTIL FOR 6 MONTHS. SUBJECTS IN WAITLIST GROUP RECEIVED NO INTERVENTION DURING THIS PERIOD. SUBJECTS WERE EVALUATED WITH WORLD HEALTH ORGANIZATION QUALITY OF LIFE (WHOQOL)-BREF FOR MEASURING QOL AND PITTSBURGH SLEEP QUALITY INDEX FOR SLEEP QUALITY IN THE BASELINE AND AFTER 6 MONTHS. STATISTICAL ANALYSIS: INDEPENDENT T-TEST AND REPEATED MEASURES ANALYSIS OF COVARIANCE RESPECTIVELY WAS USED TO MEASURE THE DIFFERENCE IN OUTCOME MEASURES BETWEEN THE TWO GROUPS AT BASELINE AND AFTER THE STUDY PERIOD. RESULTS: SUBJECTS IN THE YOGA GROUP HAD SIGNIFICANTLY HIGHER NUMBER OF YEARS OF FORMAL EDUCATION. SUBJECTS IN THE YOGA GROUP HAD SIGNIFICANT IMPROVEMENT IN ALL THE DOMAINS OF QOL AND TOTAL SLEEP QUALITY AFTER CONTROLLING FOR THE EFFECT OF BASELINE DIFFERENCE IN EDUCATION BETWEEN THE TWO GROUPS. CONCLUSION: YOGA INTERVENTION APPEARS TO IMPROVE THE QOL AND SLEEP QUALITY OF ELDERLY LIVING IN OLD AGE HOMES. THERE IS A NEED FOR FURTHER STUDIES OVERCOMING THE LIMITATIONS IN THIS STUDY TO CONFIRM THE BENEFITS OF YOGA FOR ELDERLY IN QOL AND SLEEP QUALITY.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
14  772  36 EFFECT OF YOGA AND EXERCISE ON GLYCEMIC CONTROL AND PSYCHOSOCIAL PARAMETERS IN TYPE 2 DIABETES MELLITUS: A RANDOMIZED CONTROLLED STUDY. CONTEXT BACKGROUND: TYPE 2 DIABETES HAS BEEN STRONGLY ASSOCIATED WITH PSYCHOSOCIAL FACTORS SUCH AS STRESS, ANXIETY, DEPRESSION, AND QUALITY OF LIFE (QOL). THERE IS NOT MUCH EVIDENCE WHETHER YOGA CAN IMPROVE THESE FACTORS AND MOTIVATE INDIVIDUALS TO ENGAGE IN ACTIVE LIFESTYLE. AIMS: THIS STUDY AIMS TO EVALUATE THE EFFECT OF YOGA AND EXERCISE OVER GLYCEMIC CONTROL, ANXIETY, DEPRESSION, EXERCISE SELF-EFFICACY (ESE), AND QOL AFTER 3-MONTH PROGRAM. METHODS: TWO HUNDRED AND TWENTY-SEVEN INDIVIDUALS WERE RANDOMLY ALLOCATED TO YOGA GROUP (YG) AND EXERCISE GROUP. YG PRACTICED YOGA FOR 2 WEEKS UNDER SUPERVISION AND THEN CARRIED OUT PRACTICE AT HOME FOR 3 MONTHS. THE EXERCISE GROUP PRACTICED 30 MIN OF BRISK WALKING FOR 5 DAYS A WEEK. RESULTS: ON COMPARISON AMONG THE GROUPS, IN YG, THERE WAS A MEAN CHANGE OF 0.47 IN GLYCATED HEMOGLOBIN WHICH WAS GREATER THAN MEAN REDUCTION OF 0.28 IN THE EXERCISE GROUP WITH P < 0.05. STATE ANXIETY REDUCED BY 7.8 AND TRAIT ANXIETY REDUCED BY 4.4 IN YG (P < 0.05) IN 3 MONTHS AS COMPARED TO NONSIGNIFICANT REDUCTIONS OF 3 AND 1 IN MEAN OF STATE AND TRAIT ANXIETY SCORES IN THE EXERCISE GROUP (P > 0.05). THERE WAS A STATISTICALLY SIGNIFICANT REDUCTION IN DEPRESSION SCORE IN BOTH THE GROUPS, 8.6 IN YOGA AND 4.0 IN EXERCISE, WHICH WAS GREATER IN YG. ESE IMPROVED BY 19.2 IN YG (P < 0.05), WHEREAS IT IMPROVED ONLY 2.2 IN THE EXERCISE GROUP (P > 0.05). QOL IMPROVED BY 23.7 IN YG AND 3.0 IN THE EXERCISE GROUP WHICH WAS NONSIGNIFICANT IN THE EXERCISE GROUP AS COMPARED TO YG. CONCLUSIONS: YOGA IS SUPERIOR TO EXERCISE ALONE AS A LIFESTYLE MODIFICATION PROGRAM IN IMPROVING GLYCEMIC CONTROL, ANXIETY, DEPRESSION, AND QOL AS WELL AS ESE.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
15   60  33 A COMPARISON OF THE EFFECTS OF HATHA YOGA AND RESISTANCE EXERCISE ON MENTAL HEALTH AND WELL-BEING IN SEDENTARY ADULTS: A PILOT STUDY. OBJECTIVES: PHYSICAL ACTIVITY HAS A POSITIVE EFFECT ON PEOPLE'S MENTAL HEALTH AND WELL-BEING. THE AIM OF THIS STUDY WAS TO COMPARE THE EFFECTS OF HATHA YOGA AND RESISTANCE EXERCISES ON MENTAL HEALTH AND WELL-BEING IN SEDENTARY ADULTS. DESIGN: RANDOMIZED CONTROLLED STUDY. METHODS: FIFTY-ONE PARTICIPANTS AGED MEAN (SD) 25.6 (5.7) YEARS WERE RANDOMLY DIVIDED INTO THREE GROUPS: HATHA YOGA GROUP, RESISTANCE EXERCISE GROUP AND CONTROL GROUP. THE HATHA YOGA GROUP AND RESISTANCE EXERCISE GROUP PARTICIPATED IN SESSIONS THREE DAYS PER WEEK FOR 7 WEEKS AND THE CONTROL GROUP DID NOT PARTICIPATE IN ANY SESSIONS. ALL THE SUBJECTS WERE EVALUATED THROUGH THE ROSENBERG SELF-ESTEEM SCALE, BECK DEPRESSION INVENTORY, BODY CATHEXIS SCALE, NOTTINGHAM HEALTH PROFILE AND VISUAL ANALOG SCALE FOR FATIGUE PRE-AND POST-SESSION. RESULTS: SIGNIFICANT IMPROVEMENTS WERE FOUND IN TERMS OF ALL OUTCOME MEASURES IN THE HATHA YOGA GROUP AND THE RESISTANCE EXERCISE GROUP. NO IMPROVEMENTS WERE FOUND IN THE CONTROL GROUP. HATHA YOGA MORE IMPROVED THE DIMENSIONS FATIGUE, SELF-ESTEEM, AND QUALITY OF LIFE, WHILST RESISTANCE EXERCISE TRAINING MORE IMPROVED BODY IMAGE. HATHA YOGA AND RESISTANCE EXERCISE DECREASED DEPRESSION SYMPTOMS AT A SIMILAR LEVEL. CONCLUSION: THE RESULTS INDICATED THAT HATHA YOGA AND RESISTANCE EXERCISE HAD POSITIVE EFFECTS ON MENTAL HEALTH AND WELL-BEING IN SEDENTARY ADULTS. HATHA YOGA AND RESISTANCE EXERCISE MAY AFFECT DIFFERENT ASPECTS OF MENTAL HEALTH AND WELL-BEING.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
16 1859  39 RANDOMIZED CONTROLLED PILOT TRIAL OF YOGA IN OVERWEIGHT AND OBESE BREAST CANCER SURVIVORS: EFFECTS ON QUALITY OF LIFE AND ANTHROPOMETRIC MEASURES. PURPOSE: TO OBTAIN ESTIMATES OF TIME TO RECRUIT THE STUDY SAMPLE, RETENTION, FACILITY-BASED CLASS ATTENDANCE AND HOME PRACTICE FOR A STUDY OF YOGA IN BREAST CANCER SURVIVORS, AND ITS EFFICACY ON FATIGUE, QUALITY OF LIFE (QOL), AND WEIGHT CHANGE. METHODS: SIXTY-THREE POST-TREATMENT STAGES 0-III BORDERLINE OVERWEIGHT AND OBESE (BODY MASS INDEX >/= 24 KG/M(2)) BREAST CANCER SURVIVORS WERE RANDOMLY ASSIGNED TO A 6-MONTH, FACILITY- AND HOME-BASED VINIYOGA INTERVENTION (N = 32) OR A WAITLIST CONTROL GROUP (N = 31). THE YOGA GOAL WAS FIVE PRACTICES PER WEEK. PRIMARY OUTCOME MEASURES WERE CHANGES IN QOL, FATIGUE, AND WEIGHT FROM BASELINE TO 6 MONTHS. SECONDARY OUTCOMES INCLUDED CHANGES IN WAIST AND HIP CIRCUMFERENCE. RESULTS: IT TOOK 12 MONTHS TO COMPLETE RECRUITMENT. PARTICIPANTS ATTENDED A MEAN OF 19.6 CLASSES AND PRACTICED AT HOME A MEAN OF 55.8 TIMES DURING THE 6-MONTH PERIOD. AT FOLLOW-UP, 90% OF PARTICIPANTS COMPLETED QUESTIONNAIRES AND 87% COMPLETED ANTHROPOMETRIC MEASUREMENTS. QOL AND FATIGUE IMPROVED TO A GREATER EXTENT AMONG WOMEN IN THE YOGA GROUP RELATIVE TO WOMEN IN THE CONTROL GROUP, ALTHOUGH NO DIFFERENCES WERE STATISTICALLY SIGNIFICANT. WAIST CIRCUMFERENCE DECREASED 3.1 CM (95% CI, -5.7 AND -0.4) MORE AMONG WOMEN IN THE YOGA COMPARED WITH THE CONTROL GROUP, WITH NO DIFFERENCE IN WEIGHT CHANGE. CONCLUSIONS: THIS STUDY PROVIDES IMPORTANT INFORMATION REGARDING RECRUITMENT, RETENTION, AND PRACTICE LEVELS ACHIEVED DURING A 6-MONTH, INTENSIVE YOGA INTERVENTION IN OVERWEIGHT AND OBESE BREAST CANCER SURVIVORS. YOGA MAY HELP DECREASE WAIST CIRCUMFERENCE AND IMPROVE QUALITY OF LIFE; FUTURE STUDIES ARE NEEDED TO CONFIRM THESE RESULTS.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
17 1869  35 RANDOMIZED, CONTROLLED, SIX-MONTH TRIAL OF YOGA IN HEALTHY SENIORS: EFFECTS ON COGNITION AND QUALITY OF LIFE. CONTEXT: THERE ARE POTENTIAL BENEFITS OF MIND-BODY TECHNIQUES ON COGNITIVE FUNCTION BECAUSE THE TECHNIQUES INVOLVE AN ACTIVE ATTENTIONAL OR MINDFULNESS COMPONENT, BUT THIS HAS NOT BEEN FULLY EXPLORED. OBJECTIVE: TO DETERMINE THE EFFECT OF YOGA ON COGNITIVE FUNCTION, FATIGUE, MOOD, AND QUALITY OF LIFE IN SENIORS. DESIGN: RANDOMIZED, CONTROLLED TRIAL COMPARING YOGA, EXERCISE, AND WAIT-LIST CONTROL GROUPS. PARTICIPANTS: ONE HUNDRED THIRTY-FIVE GENERALLY HEALTHY MEN AND WOMEN AGED 65-85 YEARS. INTERVENTION: PARTICIPANTS WERE RANDOMIZED TO 6 MONTHS OF HATHA YOGA CLASS, WALKING EXERCISE CLASS, OR WAIT-LIST CONTROL. SUBJECTS ASSIGNED TO CLASSES ALSO WERE ASKED TO PRACTICE AT HOME. MAIN OUTCOME MEASURES: OUTCOME ASSESSMENTS PERFORMED AT BASELINE AND AFTER THE 6-MONTH PERIOD INCLUDED A BATTERY OF COGNITIVE MEASURES FOCUSED ON ATTENTION AND ALERTNESS, THE PRIMARY OUTCOME MEASURES BEING PERFORMANCE ON THE STROOP TEST AND A QUANTITATIVE ELECTROENCEPHALOGRAM (EEG) MEASURE OF ALERTNESS; SF-36 HEALTH-RELATED QUALITY OF LIFE; PROFILE OF MOOD STATES; MULTI-DIMENSIONAL FATIGUE INVENTORY; AND PHYSICAL MEASURES RELATED TO THE INTERVENTIONS. RESULTS: ONE HUNDRED THIRTY-FIVE SUBJECTS WERE RECRUITED AND RANDOMIZED. SEVENTEEN SUBJECTS DID NOT FINISH THE 6-MONTH INTERVENTION. THERE WERE NO EFFECTS FROM EITHER OF THE ACTIVE INTERVENTIONS ON ANY OF THE COGNITIVE AND ALERTNESS OUTCOME MEASURES. THE YOGA INTERVENTION PRODUCED IMPROVEMENTS IN PHYSICAL MEASURES (EG, TIMED 1-LEGGED STANDING, FORWARD FLEXIBILITY) AS WELL AS A NUMBER OF QUALITY-OF-LIFE MEASURES RELATED TO SENSE OF WELL-BEING AND ENERGY AND FATIGUE COMPARED TO CONTROLS. CONCLUSIONS: THERE WERE NO RELATIVE IMPROVEMENTS OF COGNITIVE FUNCTION AMONG HEALTHY SENIORS IN THE YOGA OR EXERCISE GROUP COMPARED TO THE WAIT-LIST CONTROL GROUP. THOSE IN THE YOGA GROUP SHOWED SIGNIFICANT IMPROVEMENT IN QUALITY-OF-LIFE AND PHYSICAL MEASURES COMPARED TO EXERCISE AND WAIT-LIST CONTROL GROUPS.	2006	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
18  171  36 A RANDOMIZED CONTROLLED PILOT STUDY OF THE THERAPEUTIC EFFECTS OF YOGA IN PEOPLE WITH PARKINSON'S DISEASE. BACKGROUND: EXERCISE CAN BE BENEFICIAL FOR CARDIOPULMONARY, MUSCULOSKELETAL OR NEUROLOGICAL SYSTEMS, AND OTHER FACTORS INCLUDING MOOD, AND MAY BE BENEFICIAL IN REDUCING FALL RISKS, DEMENTIA AND VARIABLES ASSOCIATED WITH QUALITY OF LIFE (QOL). PARKINSON'S DISEASE (PD) PRODUCES PROGRESSIVE MOTOR AND COGNITIVE DETERIORATION THAT MAY LEAVE THOSE INFLICTED UNABLE TO PARTICIPATE IN STANDARD EXERCISE PROGRAMS. ALTERNATIVE FORMS OF EXERCISE SUCH AS YOGA MAY BE SUCCESSFUL IN IMPROVING PHYSICAL FUNCTION, QOL AND PHYSIOLOGICAL VARIABLES FOR OVERALL WELL-BEING. AIM: THIS RANDOMIZED CONTROLLED PILOT STUDY INVESTIGATED THE EFFECTIVENESS OF YOGA INTERVENTION ON PHYSIOLOGICAL AND HEALTH-RELATED QOL MEASURES IN PEOPLE WITH PD. METHODS AND MATERIALS: THIRTEEN PEOPLE WITH STAGE 1-2 PD WERE RANDOMIZED TO EITHER A YOGA (N = 8) OR A CONTROL GROUP (N = 5). THE YOGA GROUP PARTICIPATED IN TWICE-WEEKLY YOGA SESSIONS FOR 12 WEEKS. PARTICIPANTS WERE TESTED AT BASELINE, AND AT 6 AND 12 WEEKS USING THE UNIFIED PARKINSON'S DISEASE RATING SCALE (UPDRS), CLINICAL MEASURES OF HEALTH-RELATED QOL AND PHYSIOLOGICAL MEASURES. RESULTS: SIGNIFICANT IMPROVEMENT IN UPDRS SCORES (P = .006), DIASTOLIC BLOOD PRESSURE (P = 0.036) AND AVERAGE FORCED VITAL CAPACITY (P = 0.03) WAS NOTED IN THE YOGA GROUP OVER TIME. CHANGES BETWEEN GROUPS WERE ALSO NOTED IN TWO SF-36 SUBSCALES. POSITIVE TRENDS OF IMPROVEMENT WERE NOTED IN DEPRESSION SCORES (P = 0.056), BODY WEIGHT (P = 0.056) AND FORCED EXPIRATORY VOLUME (P = 0.059). YOGA PARTICIPANTS REPORTED MORE POSITIVE SYMPTOM CHANGES INCLUDING IMMEDIATE TREMOR REDUCTION. CONCLUSIONS: THE RESULTS SUGGEST THAT YOGA MAY IMPROVE ASPECTS OF QOL AND PHYSIOLOGICAL FUNCTIONS IN STAGES 1-2 PD. FUTURE LARGER STUDIES ARE NEEDED TO CONFIRM AND EXTEND OUR FINDINGS OF THE EFFECTS OF YOGA IN PD.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
19  944  42 EFFECTS OF A 12-WEEK HATHA YOGA INTERVENTION ON METABOLIC RISK AND QUALITY OF LIFE IN HONG KONG CHINESE ADULTS WITH AND WITHOUT METABOLIC SYNDROME. OBJECTIVE: TO DETERMINE THE EFFICACY OF A 12-WEEK HATHA YOGA INTERVENTION TO IMPROVE METABOLIC RISK PROFILES AND HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN CHINESE ADULTS WITH AND WITHOUT METABOLIC SYNDROME (METS). METHODS: WE CONDUCTED A CONTROLLED TRIAL WITHIN AN UNIVERSITY-AFFILIATED HOSPITAL. 173 CHINESE MEN AND WOMEN AGED 18 OR ABOVE WERE ASSIGNED TO EITHER THE YOGA INTERVENTION GROUP (N = 87) OR THE CONTROL GROUP (N = 86). PRIMARY OUTCOMES INCLUDED 12-WEEK CHANGE IN METABOLIC RISK FACTORS AND METS Z SCORE. SECONDARY OUTCOME WAS HRQOL (MEDICAL OUTCOMES SHORT FORM SURVEY AT 12 WEEKS). RESULTS: THE MEAN AGE OF PARTICIPANTS WAS 52.0 (SD 7.4, RANGE 31-71) YEARS. ANALYSIS INVOLVING THE ENTIRE STUDY POPULATION REVEALED THAT THE YOGA GROUP ACHIEVED GREATER DECLINE IN WAIST CIRCUMFERENCE (P<0.001), FASTING GLUCOSE (P<0.01), TRIGLYCERIDES (P<0.05), AND METS Z SCORE (P<0.01). YOGA TRAINING ALSO IMPROVED GENERAL HEALTH PERCEPTIONS (P<0.01), PHYSICAL COMPONENT SCORE (P<0.01), AND SOCIAL FUNCTIONING (P<0.01) DOMAINS SCORE OF HRQOL. HOWEVER, NO SIGNIFICANT DIFFERENCES BETWEEN GROUPS WERE OBSERVED IN THE MEAN CHANGE OF SYSTOLIC/DIASTOLIC BLOOD PRESSURES OR HIGH-DENSITY LIPID PROTEIN CHOLESTEROL (ALL P>0.05). THERE WERE NO SIGNIFICANT DIFFERENCES IN THE INTERVENTION EFFECTS ON WAIST CIRCUMFERENCE AND METS Z SCORE BETWEEN THE METS SUBGROUPS (BOTH P>0.05). CONCLUSION: A 12-WEEK HATHA YOGA INTERVENTION IMPROVES METABOLIC RISK PROFILES AND HRQOL IN CHINESE ADULTS WITH AND WITHOUT METS. TRIAL REGISTRATION: AUSTRALIAN NEW ZEALAND CLINICAL TRIALS REGISTRY ACTRN12613000816752.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
20   35  49 A 12-WEEK YOGA-BASED LIFESTYLE INTERVENTION MIGHT POSITIVELY MODIFY CELLULAR AGING IN INDIAN OBESE INDIVIDUALS: A RANDOMIZED-CONTROLLED TRIAL. BACKGROUND: TELOMERES AND TELOMERASE ARE CONSIDERED CARDINAL BIOMARKERS OF CELLULAR AGING. SHORTER TELOMERES AND LOW TELOMERASE ACTIVITY HAVE BEEN ASSOCIATED WITH OBESITY AND ACCELERATED AGING. OBJECTIVE: TO COMPARE THE EFFECTS OF A YOGA-BASED LIFESTYLE INTERVENTION (YBLI) WITH THE STANDARD OF CARE (SOC) ON CELLULAR AGING BY ESTIMATING TELOMERE LENGTH (TL) AND TELOMERASE ACTIVITY IN OBESITY. DESIGN AND SETTING: A PARALLEL, TWO-ARM, RANDOMIZED-CONTROLLED TRIAL WAS CONDUCTED AT THE INTEGRAL HEALTH CLINIC, DEPARTMENT OF PHYSIOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, FROM MARCH 2017 TO OCTOBER 2019. PARTICIPANTS: OBESE (N = 72), BODY MASS INDEX (BMI), 25-35 KG/M(2), AGED 20-45 YEARS, MALE (21), AND FEMALE (51). INTERVENTION: SEVENTY-TWO OBESE PARTICIPANTS WERE RANDOMIZED TO RECEIVE EITHER A 12-WEEK SOC (N = 36) OR YBLI (N = 36). SOC INCLUDED MANAGEMENT OF OBESITY AS PER INDIAN GUIDELINES INCLUDING A HYPOCALORIC INDIVIDUALIZED DIET AND PHYSICAL ACTIVITY. THE PRETESTED YBLI INCLUDED ASANA (PHYSICAL POSTURES), PRANAYAMA (BREATHING EXERCISES), AND MEDITATION. METHODS: BLOOD SAMPLES WERE COLLECTED FROM BOTH THE GROUPS AT BASELINE, 2, 4, AND 12 WEEKS. DNA WAS EXTRACTED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS. TL WAS MEASURED BY QUANTITATIVE PCR, AND SERUM TELOMERASE LEVELS BY IMMUNOASSAY. OUTCOME MEASURES: PRIMARY OUTCOME MEASURES WERE THE CHANGES IN THE TL AND TELOMERASE LEVELS BETWEEN THE TWO GROUPS AT WEEK 12. SECONDARY OUTCOME MEASURES WERE THE CHANGES IN TL AND TELOMERASE, AND ANTHROPOMETRIC PARAMETERS (BODY WEIGHT, BMI, WAIST-TO-HIP RATIO) AT 2, 4, AND 12 WEEKS OF INTERVENTION IN BOTH SOC AND YBLI GROUPS. RESULTS: THERE WERE NO SIGNIFICANT CHANGES IN TL AND TELOMERASE LEVELS BETWEEN THE GROUPS AT WEEK 12. THE TL WAS SIGNIFICANTLY GREATER IN THE YBLI GROUP VERSUS THE SOC GROUP (P < 0.0001) AT 2 WEEKS. THE ANTHROPOMETRIC AND PHYSIOLOGICAL PARAMETERS WERE INFLUENCED POSITIVELY BY BOTH SOC AND YBLI. CONCLUSION: THE STUDY DID NOT MEET THE PRIMARY OBJECTIVE, ALTHOUGH THE RESULTS ARE SUGGESTIVE OF A POSITIVE IMPACT OF YBLI ON AGING IN OBESITY AS NOTED WITHIN THE YBLI GROUP. HOWEVER, THE RESULTS SHOULD BE INTERPRETED CAREFULLY, AND IN THE LIGHT OF OTHER PUBLISHED DATA. LARGER STUDIES TO BETTER UNDERSTAND THE POSSIBLE POSITIVE BENEFITS OF YBLI ON CELLULAR AGING ARE RECOMMENDED. CLINICAL TRAIL REGISTRATION NO. CTRI/2016/08/007136.	2022