1 1273 184 FRONTAL HEMODYNAMIC RESPONSES TO HIGH FREQUENCY YOGA BREATHING IN SCHIZOPHRENIA: A FUNCTIONAL NEAR-INFRARED SPECTROSCOPY STUDY. FRONTAL HEMODYNAMIC RESPONSES TO HIGH FREQUENCY YOGA BREATHING TECHNIQUE, KAPALABHATI (KB), WERE COMPARED BETWEEN PATIENTS OF SCHIZOPHRENIA (N = 18; 14 MALES, 4 FEMALES) AND AGE, GENDER, AND EDUCATION MATCHED HEALTHY SUBJECTS (N = 18; 14 MALES, 4 FEMALES) USING FUNCTIONAL NEAR-INFRARED SPECTROSCOPY. THE DIAGNOSIS WAS CONFIRMED BY A PSYCHIATRIST USING DSM-IV. ALL PATIENTS EXCEPT ONE RECEIVED ATYPICAL ANTIPSYCHOTICS (ONE WAS ON TYPICAL). THEY HAD OBTAINED A STABILIZED STATE AS EVIDENCED BY A STEADY UNCHANGED MEDICATION FROM THEIR PSYCHIATRIST FOR THE PAST 3 MONTHS OR LONGER. THEY LEARNED KB, AMONG OTHER YOGA PROCEDURES, IN A YOGA RETREAT. KB WAS PRACTICED AT THE RATE OF 120 TIMES/MIN FOR 1 MIN. HEALTHY SUBJECTS WHO WERE FRESHLY LEARNING YOGA TOO WERE TAUGHT KB. BOTH THE GROUPS HAD NO PREVIOUS EXPOSURE TO KB PRACTICE AND THE TRAINING WAS CARRIED OUT OVER 2 WEEKS. A CHEST PRESSURE TRANSDUCER WAS USED TO MONITOR THE FREQUENCY AND INTENSITY OF THE PRACTICE OBJECTIVELY. THE FRONTAL HEMODYNAMIC RESPONSE IN TERMS OF THE OXYGENATED HEMOGLOBIN (OXYHB), DEOXYGENATED HEMOGLOBIN (DEOXYHB), AND TOTAL HEMOGLOBIN (TOTALHB) OR BLOOD VOLUME CONCENTRATION WAS TAPPED FOR 5 MIN BEFORE, 1 MIN DURING, AND FOR 5 MIN AFTER KB. THIS WAS OBTAINED IN A QUIET ROOM USING A 16-CHANNEL FUNCTIONAL NEAR-INFRARED SYSTEM (FNIR100-ACK-W, BIOPAC SYSTEMS, INC., USA). THE AVERAGE OF THE EIGHT CHANNELS FOR EACH SIDE (RIGHT AND LEFT FRONTALS) WAS OBTAINED FOR THE THREE SESSIONS. THE CHANGES IN THE LEVELS OF OXYHB, DEOXYHB, AND BLOOD VOLUME FOR THE THREE SESSIONS WERE COMPARED BETWEEN THE TWO GROUPS USING INDEPENDENT SAMPLES T-TEST. WITHIN GROUP COMPARISON SHOWED THAT THE INCREASE IN BILATERAL OXYHB AND TOTALHB FROM THE BASELINE WAS HIGHLY SIGNIFICANT IN HEALTHY CONTROLS DURING KB (RIGHT OXYHB, P = 0.00; LEFT OXYHB, P = 0.00 AND RIGHT TOTALHB, P = 0.01; LEFT TOTALHB, P = 0.00), WHEREAS SCHIZOPHRENIA PATIENTS DID NOT SHOW ANY SIGNIFICANT CHANGES IN THE SAME ON BOTH THE SIDES. ON THE OTHER HAND, SCHIZOPHRENIA PATIENTS SHOWED SIGNIFICANT REDUCTION IN DEOXYHB IN THE RIGHT PRE-FRONTAL CORTEX (RIGHT DEOXYHB, P = 0.00). COMPARISON BETWEEN THE GROUPS SHOWED THAT SCHIZOPHRENIA PATIENTS HAVE REDUCED BILATERAL PRE-FRONTAL ACTIVATION (RIGHT OXYHB, P = 0.01; LEFT OXYHB, P = 0.03 AND RIGHT TOTAL HB, P = 0.03; LEFT TOTAL HB, P = 0.04) DURING KB AS COMPARED TO HEALTHY CONTROLS. THIS HYPO-FRONTALITY OF SCHIZOPHRENIA PATIENTS IN RESPONSE TO KB MAY BE USED CLINICALLY TO SUPPORT THE DIAGNOSIS OF SCHIZOPHRENIA IN FUTURE.	2014	

2  770  82 EFFECT OF UNINOSTRIL YOGA BREATHING ON BRAIN HEMODYNAMICS: A FUNCTIONAL NEAR-INFRARED SPECTROSCOPY STUDY. OBJECTIVES: TO MEASURE THE EFFECT OF THE RIGHT AND LEFT NOSTRIL YOGA BREATHING ON FRONTAL HEMODYNAMIC RESPONSES IN 32 RIGHT HANDED HEALTHY MALE SUBJECTS WITHIN THE AGE RANGE OF 18-35 YEARS (23.75 +/- 4.14 YEARS). MATERIALS AND METHODS: EACH SUBJECT PRACTICED RIGHT NOSTRIL YOGA BREATHING (RNYB), LEFT NOSTRIL YOGA BREATHING (LNYB) OR BREATH AWARENESS (BA) (AS CONTROL) FOR 10 MIN AT THE SAME TIME OF THE DAY FOR THREE CONSECUTIVE DAYS, RESPECTIVELY. THE SEQUENCE OF INTERVENTION WAS ASSIGNED RANDOMLY. THE FRONTAL HEMODYNAMIC RESPONSE IN TERMS OF CHANGES IN THE OXYGENATED HEMOGLOBIN (OXYHB), DEOXYGENATED HEMOGLOBIN (DEOXYHB), AND TOTAL HEMOGLOBIN (TOTALHB OR BLOOD VOLUME) CONCENTRATION WAS TAPPED FOR 5 MIN BEFORE (PRE) AND 10 MIN DURING THE BREATHING PRACTICES USING A 16 CHANNEL FUNCTIONAL NEAR-INFRARED SYSTEM (FNIR100-ACK-W, BIOPAC SYSTEMS, INC., U.S.A.). AVERAGE OF THE EIGHT CHANNELS ON EACH SIDE (RIGHT AND LEFT FRONTALS) WAS OBTAINED FOR THE TWO SESSIONS (PRE AND DURING). DATA WAS ANALYZED USING SPSS VERSION 10.0 THROUGH PAIRED AND INDEPENDENT SAMPLES T-TEST. RESULTS: WITHIN GROUP COMPARISON SHOWED THAT DURING RNYB, OXYHB LEVELS INCREASED SIGNIFICANTLY IN THE LEFT PREFRONTAL CORTEX (PFC) AS COMPARED TO THE BASELINE (P = 0.026). LNYB SHOWED A TREND TOWARDS SIGNIFICANCE FOR REDUCTION IN OXYHB IN THE RIGHT HEMISPHERE (P = 0.057). WHEREAS BA CAUSED SIGNIFICANT REDUCTION IN DEOXYHB (P = 0.023) IN THE LEFT HEMISPHERE. BETWEEN GROUPS COMPARISON REVEALED THAT OXYHB AND BLOOD VOLUME IN THE LEFT PFC INCREASED SIGNIFICANTLY DURING RNYB AS COMPARED TO BA (OXYHB: P =0.012; TOTALHB: P =0.017) AND LNYB (OXYHB: P =0.024; TOTALHB: P =0.034). CONCLUSION: RNYB INCREASED OXYGENATION AND BLOOD VOLUME IN THE LEFT PFC AS COMPARED TO BA AND LNYB. THIS SUPPORTS THE RELATIONSHIP BETWEEN NASAL CYCLE AND ULTRADIAN RHYTHM OF CEREBRAL DOMINANCE AND SUGGESTS A POSSIBLE APPLICATION OF UNINOSTRIL YOGA BREATHING IN THE MANAGEMENT OF PSYCHOPATHOLOGICAL STATES WHICH SHOW LATERALIZED CEREBRAL DYSFUNCTIONS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
3 1353  33 IMMEDIATE EFFECT OF SPECIFIC NOSTRIL MANIPULATING YOGA BREATHING PRACTICES ON AUTONOMIC AND RESPIRATORY VARIABLES. THE EFFECT OF RIGHT, LEFT, AND ALTERNATE NOSTRIL YOGA BREATHING (I.E., RNYB, LNYB, AND ANYB, RESPECTIVELY) WERE COMPARED WITH BREATH AWARENESS (BAW) AND NORMAL BREATHING (CTL). AUTONOMIC AND RESPIRATORY VARIABLES WERE STUDIED IN 21 MALE VOLUNTEERS WITH AGES BETWEEN 18 AND 45 YEARS AND EXPERIENCE IN THE YOGA BREATHING PRACTICES BETWEEN 3 AND 48 MONTHS. SUBJECTS WERE ASSESSED IN FIVE EXPERIMENTAL SESSIONS ON FIVE SEPARATE DAYS. THE SESSIONS WERE IN FIXED POSSIBLE SEQUENCES AND SUBJECTS WERE ASSIGNED TO A SEQUENCE RANDOMLY. EACH SESSION WAS FOR 40 MIN; 30 MIN FOR THE BREATHING PRACTICE, PRECEDED AND FOLLOWED BY 5 MIN OF QUIET SITTING. ASSESSMENTS INCLUDED HEART RATE VARIABILITY, SKIN CONDUCTANCE, FINGER PLETHYSMOGRAM AMPLITUDE, BREATH RATE, AND BLOOD PRESSURE. FOLLOWING RNYB THERE WAS A SIGNIFICANT INCREASE IN SYSTOLIC, DIASTOLIC AND MEAN PRESSURE. IN CONTRAST, THE SYSTOLIC AND DIASTOLIC PRESSURE DECREASED AFTER ANYB AND THE SYSTOLIC AND MEAN PRESSURE WERE LOWER AFTER LNYB. HENCE, UNILATERAL NOSTRIL YOGA BREATHING PRACTICES APPEAR TO INFLUENCE THE BLOOD PRESSURE IN DIFFERENT WAYS. THESE EFFECTS SUGGEST POSSIBLE THERAPEUTIC APPLICATIONS.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
4 2863  36 YOGA-BASED GUIDED RELAXATION REDUCES SYMPATHETIC ACTIVITY JUDGED FROM BASELINE LEVELS. 35 MALE VOLUNTEERS WHOSE AGES RANGED FROM 20 TO 46 YEARS WERE STUDIED IN TWO SESSIONS OF YOGA-BASED GUIDED RELAXATION AND SUPINE REST. ASSESSMENTS OF AUTONOMIC VARIABLES WERE MADE FOR 15 SUBJECTS, BEFORE, DURING, AND AFTER THE PRACTICES, WHEREAS OXYGEN CONSUMPTION AND BREATH VOLUME WERE RECORDED FOR 25 SUBJECTS BEFORE AND AFTER BOTH TYPES OF RELAXATION. A SIGNIFICANT DECREASE IN OXYGEN CONSUMPTION AND INCREASE IN BREATH VOLUME WERE RECORDED AFTER GUIDED RELAXATION (PAIRED T TEST). THERE WERE COMPARABLE REDUCTIONS IN HEART RATE AND SKIN CONDUCTANCE DURING BOTH TYPES OF RELAXATION. DURING GUIDED RELAXATION THE POWER OF THE LOW FREQUENCY COMPONENT OF THE HEART-RATE VARIABILITY SPECTRUM REDUCED, WHEREAS THE POWER OF THE HIGH FREQUENCY COMPONENT INCREASED, SUGGESTING REDUCED SYMPATHETIC ACTIVITY. ALSO, SUBJECTS WITH A BASELINE RATIO OF LF/HF > 0.5 SHOWED A SIGNIFICANT DECREASE IN THE RATIO AFTER GUIDED RELAXATION, WHILE SUBJECTS WITH A RATIO < OR = 0.5 AT BASELINE SHOWED NO SUCH CHANGE. THE RESULTS SUGGEST THAT SYMPATHETIC ACTIVITY DECREASED AFTER GUIDED RELAXATION BASED ON YOGA, DEPENDING ON THE BASELINE LEVELS.	2002	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
5  306  44 AN EVALUATION OF THE ABILITY TO VOLUNTARILY REDUCE THE HEART RATE AFTER A MONTH OF YOGA PRACTICE. THE STUDY AIMED AT DETERMINING WHETHER NOVICES TO YOGA WOULD BE ABLE TO REDUCE THEIR HEART RATE VOLUNTARILY AND WHETHER THE MAGNITUDE OF REDUCTION WOULD BE MORE AFTER 30 DAYS OF YOGA TRAINING. TWO GROUPS (YOGA AND CONTROL, N = 12 EACH) WERE ASSESSED ON DAY 1 AND ON DAY 30. DURING THE INTERVENING 30 DAYS, THE YOGA GROUP RECEIVED TRAINING IN YOGA TECHNIQUES WHILE THE CONTROL GROUP CARRIED ON WITH THEIR ROUTINE. AT EACH ASSESSMENT THE BASELINE HEART RATE WAS RECORDED FOR ONE MINUTE, THIS WAS FOLLOWED BY A SIX-MINUTE PERIOD DURING WHICH PARTICIPANTS WERE ASKED TO ATTEMPT TO VOLUNTARILY REDUCE THEIR HEART RATE, USING ANY STRATEGY. BOTH THE BASELINE HEART RATE AND THE LOWEST HEART RATE ACHIEVED VOLUNTARILY DURING THE SIX-MINUTE PERIOD WERE SIGNIFICANTLY LOWER IN THE YOGA GROUP ON DAY 30 COMPARED TO DAY 1 BY A GROUP AVERAGE OF 10.7 BEATS PER MINUTE (I.E., BPM) AND 6.8 BPM, RESPECTIVELY (P < .05, WILCOXON PAIRED SIGNED RANKS TEST). IN CONTRAST, THERE WAS NO SIGNIFICANT CHANGE IN EITHER THE BASELINE HEART RATE OR THE LOWEST HEART RATE ACHIEVED VOLUNTARILY IN THE CONTROL GROUP ON DAY 30 COMPARED TO DAY 1. THE RESULTS SUGGEST THAT YOGA TRAINING CAN ENABLE PRACTITIONERS TO USE THEIR OWN STRATEGIES TO REDUCE THE HEART RATE, WHICH HAS POSSIBLE THERAPEUTIC APPLICATIONS.	2004	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
6 1102  41 EFFECTS OF YOGA TRAINING ON BODY COMPOSITION AND OXIDANT-ANTIOXIDANT STATUS AMONG HEALTHY MALE. BACKGROUND: THE STRESSFUL CONDITION MAY CAUSE OXIDATIVE STRESS, WHICH IS RESPONSIBLE FOR VARIOUS DISEASES. AIMS: THE PRESENT STUDY WAS DESIGNED TO FIND OUT WHETHER YOGA HAS IMPACT ON THE REDUCTION OF OXIDATIVE STRESS. METHODS: FOR THE PRESENT STUDY, 95 (N = 95) HEALTHY MALE VOLUNTEERS WITHIN THE AGE GROUP OF 18-24 YEARS WERE INCLUDED, 35 (N = 35) VOLUNTEERS WERE EXCLUDED. THE REMAINING 60 (N = 60) VOLUNTEERS WERE RANDOMLY DIVIDED INTO TWO GROUPS: (A) YOGA GROUP (N = 30) AND (B) CONTROL GROUP (N = 30). YOGA TRAINING WAS GIVEN FOR 60 MIN PER DAY, 6 DAYS PER WEEK FOR 12 WEEKS IN THE YOGA GROUP, WITH NO YOGA TRAINING IN CONTROL GROUP. ASSESSMENT OF BODY COMPOSITION AND OXIDANT-ANTIOXIDANT STATUS WERE PERFORMED IN BOTH THE GROUPS AT BASELINE, BEFORE YOGA TRAINING (0 WEEK) AND AFTER (12 WEEKS) OF THE TRAINING. RESULTS: SIGNIFICANT REDUCTION (P < 0.001) IN THE PERCENTAGE OF BODY FAT AND MALONDIALDEHYDE; SIGNIFICANT ELEVATION (P < 0.001) IN SUPEROXIDE DISMUTASE, CATALASE, REDUCED GLUTATHIONE AND ASCORBIC ACID LEVELS WERE NOTED IN THE YOGA GROUP AFTER 12 WEEKS WHEN COMPARED TO BASELINE DATA (0 WEEK). HOWEVER, THERE WAS NO SIGNIFICANT DIFFERENCE IN HEIGHT, WEIGHT, BODY MASS INDEX, BODY SURFACE AREA AND LEAN BODY MASS AMONG THE YOGA GROUP AFTER 12 WEEKS WHEN COMPARED TO BASELINE DATA. THESE CHANGES MIGHT BE DUE TO YOGA TRAINING. CONCLUSIONS: REGULAR YOGA PRACTICE REDUCES BODY FAT AND OXIDATIVE STRESS. YOGA TRAINING MAY BE HELPFUL TO REDUCE THE CHANCE OF OCCURRENCE OF VARIOUS DISEASES AND HELPS TO MAINTAIN NORMAL HEALTHY LIFESTYLE.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
7 1835  30 PSYCHOPHYSIOLOGICAL CHANGES AT THE TIME OF EXAMINATION IN MEDICAL STUDENTS BEFORE AND AFTER THE PRACTICE OF YOGA AND RELAXATION. THE EFFECT OF YOGA AND RELAXATION CHANGES IN PSYCHOPHYSIOLOGICAL PARAMETERS IN RESPONSE TO THE STRESS OF EXAMINATION IN 75 MEDICAL STUDENTS WAS STUDIED. INITIALLY FIVE PARAMETERS (ANXIETY LEVEL, HEART RATE, BLOOD PRESSURE, GALVANIC SKIN RESISTANCE AND CHOICE REACTION TIME) WERE RECORDED, A MONTH BEFORE THE EXAMINATION AND ON THE DAY OF EXAMINATION. STUDENTS WERE THEN RANDOMLY DIVIDED INTO 3 GROUP OF 25 EACH. ONE GROUP PRACTICED YOGA (GROUP- Y), AND ANOTHER GROUP PRACTICED RELAXATION (GROUP-R) REGULARLY FOR THREE MONTHS. THE THIRD GROUP WAS CONTROL GROUP (GROUP-C). ALL THE PARAMETERS WERE RECORDED AFTER THE CHANGES IN ANXIETY LEVEL, HEART RATE, BLOOD PRESSURE, AND GALVANIC SKIN RESISTANCE IN RESPONSE TO STRESS OF EXAMINATION WERE SIGNIFICANTLY ATTENUATED AND THERE WAS SIGNIFICANT IMPROVEMENT IN CHOICE REACTION TIME IN GROUP-Y AND GROUP-R AS COMPARED TO GROUP-C AFTER YOGA AND RELAXATION.	1998	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
8  300  29 AN ASSESSMENT OF A SEQUENCE OF YOGA EXERCISES TO PATIENTS WITH ARTERIAL HYPERTENSION. THIS QUASI-EXPERIMENTAL STUDY DESCRIBES THE EFFECTS OF A YOGA SEQUENCE FOLLOWING HEMODYNAMIC AND BIOCHEMICAL PARAMETERS IN PATIENTS WITH HYPERTENSION. THIRTY-THREE VOLUNTEERS PARTICIPATED IN THE STUDY (CONTROL = 16 AND YOGA = 17) FOR FOUR MONTHS. BLOOD PRESSURE MEASUREMENTS, CARDIAC AND RESPIRATORY RATE WERE COLLECTED MONTHLY, WHILE THE BIOCHEMICAL PROFILE WAS TAKEN AT THE BEGINNING AND END OF THE PROGRAM. TO ANALYZE THE DATA, STUDENT'S T TEST AND REPEATED MEASURES ANALYSES WERE PERFORMED. THE YOGA GROUP SHOWED A SIGNIFICANT REDUCTION OF SYSTOLIC BLOOD PRESSURE, HEART AND RESPIRATORY RATE (P < 0.05). AS FOR THE BIOCHEMICAL PROFILE, THE YOGA GROUP SHOWED CORRELATION COEFFICIENTS BETWEEN INITIAL VALUES AND FINAL RESPONSES GREATER THAN THE CONTROL OF FASTING GLUCOSE, TOTAL CHOLESTEROL, LDL-CHOLESTEROL AND TRIGLYCERIDES. THE ELABORATED SEQUENCE PRACTICE PROMOTED SIGNIFICANT CARDIOVASCULAR AND METABOLIC BENEFITS. THE YOGA EXERCISES PERFORMED IN THE PROPOSED SEQUENCE CONSTITUTE COMPLEMENTARY NON-PHARMACOLOGICAL CONTROL OF BLOOD PRESSURE IN PATIENTS WITH HYPERTENSION.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
9  297  35 ALTERNATE NOSTRIL BREATHING AT DIFFERENT RATES AND ITS INFLUENCE ON HEART RATE VARIABILITY IN NON PRACTITIONERS OF YOGA. INTRODUCTION: HEART RATE VARIABILITY IS A MEASURE OF MODULATION IN AUTONOMIC INPUT TO THE HEART AND IS ONE OF THE MARKERS OF AUTONOMIC FUNCTIONS. THOUGH THERE ARE MANY STUDIES ON THE LONG TERM INFLUENCE OF BREATHING ON HRV (HEART RATE VARIABILITY) THERE ARE ONLY A FEW STUDIES ON THE IMMEDIATE EFFECT OF BREATHING ESPECIALLY ALTERNATE NOSTRIL BREATHING ON HRV. THIS STUDY FOCUSES ON THE IMMEDIATE EFFECTS OF ALTERNATE NOSTRIL BREATHING AND THE INFLUENCE OF DIFFERENT BREATHING RATES ON HRV. MATERIALS AND METHODS: THE STUDY WAS DONE ON 25 SUBJECTS IN THE AGE GROUP OF 17-35 YEARS. ECG AND RESPIRATION WERE RECORDED BEFORE INTERVENTION AND IMMEDIATELY AFTER THE SUBJECTS WERE ASKED TO PERFORM ALTERNATE NOSTRIL BREATHING FOR FIVE MINUTES. RESULTS: LOW FREQUENCY (LF) WHICH IS A MARKER OF SYMPATHETIC ACTIVITY INCREASED, HIGH FREQUENCY (HF) WHICH IS A MARKER OF PARASYMPATHETIC ACTIVITY DECREASED AND THEIR RATIO LF/HF WHICH IS A MARKER OF SYMPATHO/VAGAL BALANCE INCREASED IMMEDIATELY AFTER 6 AND 12 MINUTES IN COMPARISON TO BASELINE VALUES WHEREAS THERE WAS NO SIGNIFICANT DIFFERENCE IN THE MEANS OF THESE COMPONENTS WHEN BOTH 6 AND 12 MINUTES WERE COMPARED. CONCLUSION: IMMEDIATE EFFECTS OF ALTERNATE NOSTRIL BREATHING ON HRV IN NON PRACTITIONERS OF YOGIC BREATHING ARE VERY DIFFERENT FROM THE LONG TERM INFLUENCE OF YOGIC BREATHING ON HRV WHICH SHOW A PREDOMINANT PARASYMPATHETIC INFLUENCE ON THE HEART.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
10 1318  45 HEART RATE VARIABILITY IN CHRONIC LOW BACK PAIN PATIENTS RANDOMIZED TO YOGA OR STANDARD CARE. BACKGROUND: CHRONIC PAIN CAN ALTER THE AUTONOMIC BALANCE WITH INCREASED SYMPATHETIC ACTIVITY REFLECTED IN ALTERED HEART RATE VARIABILITY (HRV). IT HAS BEEN PROPOSED THAT YOGA CAN BE USEFUL TO CORRECT THE AUTONOMIC IMBALANCE IN PATIENTS WITH CHRONIC PAIN WHO HAVE REDUCED HRV. METHODS AND DESIGNS: IN THE PRESENT RANDOMIZED CONTROLLED TRIAL 62 PATIENTS WITH CHRONIC LOW BACK PAIN ASSOCIATED WITH ALTERED ALIGNMENT OF INTERVERTEBRAL DISCS (AGED BETWEEN 20 AND 45 YEARS, 32 MALES) WERE RANDOMIZED TO 2 GROUPS. ONE GROUP RECEIVED YOGA FOR 3 MONTHS WHILE THE OTHER GROUP CARRIED OUT STANDARD MEDICAL CARE BASED ON THE PHYSICIAN'S ADVICE. THE DURATION WAS THE SAME, I.E., 3 MONTHS. THE HEART RATE VARIABILITY AND RATE OF RESPIRATION WERE ASSESSED AT BASELINE AND AT THE END OF 3 MONTHS. RESULTS: THERE WAS A SIGNIFICANT DIFFERENCE IN THE BASELINE (PRE) VALUES BETWEEN GROUPS (P = 0.008) FOR RESPIRATION RATE WHICH WAS HIGHER IN THE YOGA GROUP. THE CHANGES REPORTED BELOW ARE PRE-POST COMPARISONS WITHIN EACH GROUP. THE YOGA GROUP SHOWED A SIGNIFICANT (P < 0.05; REPEATED MEASURES ANOVA, POST-HOC ANALYSES) DECREASE IN THE LF POWER OF HRV, RATE OF RESPIRATION AND A SIGNIFICANT INCREASE IN THE HF POWER OF HRV AND IN THE PNN50. CONCLUSION: THE RESULTS SUGGEST THAT YOGA PRACTICE CAN SHIFT THE AUTONOMIC BALANCE TOWARDS VAGAL DOMINANCE IN PATIENTS WITH CHRONIC LOW BACK PAIN ASSOCIATED WITH ALTERED ALIGNMENT OF INTERVERTEBRAL DISCS. TRIAL REGISTRATION: THE STUDY IS REGISTERED WITH THE CLINICAL TRIALS REGISTRY OF INDIA ( CTRI/2012/11/003094 ) AND CAN BE ACCESSED AT.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
11  463  39 CHANGES IN SHAPE AND SIZE DISCRIMINATION AND STATE ANXIETY AFTER ALTERNATE-NOSTRIL YOGA BREATHING AND BREATH AWARENESS IN ONE SESSION EACH. BACKGROUND YOGA BREATHING TECHNIQUES LIKE HIGH-FREQUENCY YOGA BREATHING (HFYB) AND BREATH AWARENESS (BAW) HAVE BEEN ASSOCIATED WITH IMPROVED PERFORMANCE IN THE SHAPE AND SIZE DISCRIMINATION TASK. A PUBMED SEARCH OF THE LITERATURE REVEALED THAT ALTERNATE-NOSTRIL BREATHING HAS BEEN SHOWN TO IMPROVE PERFORMANCE IN ATTENTION TASKS, BUT THE EFFECT ON TACTILE PERCEPTION HAS NOT BEEN STUDIED. HENCE, THE PRESENT STUDY WAS DESIGNED TO ASSESS THE IMMEDIATE EFFECTS OF ALTERNATE-NOSTRIL YOGA BREATHING (ANYB) COMPARED TO BREATH AWARENESS ON SHAPE AND SIZE DISCRIMINATION AND STATE ANXIETY. MATERIAL AND METHODS FIFTY HEALTHY MALE VOLUNTEERS AGES 20-50 YEARS (GROUP MEAN +/-S.D., 28.4+/-8.2 YEARS) WERE RECRUITED. EACH PARTICIPANT WAS ASSESSED IN 3 SESSIONS CONDUCTED ON 3 SEPARATE DAYS AT THE SAME TIME OF DAY. THE 3 SESSIONS WERE (I) ALTERNATE-NOSTRIL YOGA BREATHING (ANYB), (II) BREATH AWARENESS (BAW), AND (III) QUIET SITTING (QS), AND THE SEQUENCE OF THE SESSIONS WAS RANDOMLY ALLOCATED. THE SHAPE AND SIZE DISCRIMINATION TASK AND STATE ANXIETY WERE ASSESSED BEFORE AND AFTER ALL 3 SESSIONS. REPEATED MEASURES ANALYSIS OF VARIANCE (RM-ANOVA) FOLLOWED BY POST HOC TESTS FOR MULTIPLE COMPARISONS, WHICH WERE BONFERRONI-ADJUSTED, WERE PERFORMED TO COMPARE DATA BEFORE AND AFTER ALL 3 SESSIONS USING SPSS VERSION 18.0. RESULTS THE ERRORS SCORES IN THE SHAPE AND SIZE DISCRIMINATION TASK SHOWED A SIGNIFICANT REDUCTION AFTER THE ANYB SESSION (P<0.001). A SIGNIFICANT REDUCTION WAS FOUND IN THE LEVEL OF STATE ANXIETY AFTER BREATH AWARENESS (P<0.05) AND QUIET SITTING SESSIONS (P<0.001). CONCLUSIONS THE PRESENT RESULTS SUGGEST THAT ANYB: (I) IMPROVES PERFORMANCE IN A TASK WHICH REQUIRES PERCEPTUAL SENSITIVITY AND FOCUSED ATTENTION, BUT (II) DOES NOT REDUCE STATE ANXIETY FOLLOWING THIS TASK.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
12 2364  39 VOLUNTARY HEART RATE REDUCTION FOLLOWING YOGA USING DIFFERENT STRATEGIES. BACKGROUND/AIMS: ONE MONTH OF YOGA TRAINING HAS BEEN SHOWN TO REDUCE THE PULSE RATE VOLUNTARILY WITHOUT USING EXTERNAL CUES. HENCE, THE PRESENT STUDY WAS DESIGNED TO UNDERSTAND THE STRATEGIES USED BY YOGA PRACTITIONERS AND AUTONOMIC CHANGES ASSOCIATED WITH VOLUNTARY HEART RATE REDUCTION. MATERIALS AND METHODS: FIFTY VOLUNTEERS (GROUP MEAN AGE +/- S.D., 25.4 +/- 4.8 YEARS; 25 MALES) WERE ASSESSED IN TWO TRIALS ON SEPARATE DAYS. EACH TRIAL WAS FOR 12 MINUTES, WITH A 'PRE' STATE AND 'DURING' STATE OF 6 MINUTES EACH. FOR BOTH TRIALS THE 'PRE' STATE WAS RELAXATION WITH EYES CLOSED. IN THE 'DURING' STATE OF TRIAL I, SUBJECTS WERE ASKED TO VOLUNTARILY REDUCE THEIR HEART RATE USING A STRATEGY OF THEIR CHOICE. FROM THEIR RESPONSES TO SPECIFIC QUESTIONS IT WAS DETERMINED THAT 22 OUT OF 50 PERSONS USED BREATH REGULATION AS A STRATEGY. HENCE, IN THE 'DURING' STATE OF TRIAL II, SUBJECTS WERE ASKED TO VOLUNTARILY REDUCE THEIR HEART RATE BY BREATH REGULATION. RESULTS: IN THE FIRST TRIAL, THE HEART RATE WAS REDUCED BY AN AVERAGE OF 19.6 BEATS PER MINUTE AND IN THE SECOND TRIAL (WITH BREATH REGULATION EXCLUSIVELY) AN AVERAGE DECREASE OF 22.2 BEATS PER MINUTE WAS ACHIEVED. CONCLUSIONS: HENCE, THE STRATEGY USED DID NOT MARKEDLY ALTER THE OUTCOME.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
13  810  51 EFFECT OF YOGA ON BLOOD GLUCOSE LEVELS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. INTRODUCTION: IN VIEW OF PEOPLE EMBRACING SEDENTARY LIFE STYLE, AND THE EFFECTIVENESS OF TREATMENT BECOMING LESS, THE ROLE OF REGULAR EXERCISE ESPECIALLY 'YOGA' SEEMS TO BE A BENEFICIAL AND ECONOMICAL ADJUVANT IN THE MANAGEMENT OF THE TYPE 2 DIABETES MELLITUS (T2DM). OBJECTIVES: TO ASSESS THE BENEFICIAL EFFECTS OF YOGA ON BLOOD GLUCOSE LEVELS IN NORMAL AND T2DM VOLUNTEERS. MATERIALS AND METHODS: A PROSPECTIVE CASE-CONTROL STUDY WAS CONDUCTED IN THE DEPARTMENT OF PHYSIOLOGY AND DIABETIC CLINIC OF A TERTIARY CARE TEACHING HOSPITAL OVER PERIOD OF TWO YEARS. THE STUDY SUBJECTS CONSISTED OF 30 MALE DIABETIC PATIENTS ATTENDING DIABETIC CLINIC AND 30 NON-DIABETIC MALE VOLUNTEERS CONSTITUTED CONTROL GROUP. THE PATIENTS IN THE AGE GROUP OF 36 TO 55 YEARS WITH T2DM OF AT LEAST ONE YEAR DURATION AND THOSE ON DIABETIC DIET AND ORAL HYPOGLYCEMIC AGENTS WERE INCLUDED IN THE STUDY GROUP. THE AGE MATCHED HEALTHY MALE VOLUNTEERS WHO HAD COME TO JOIN YOGA TRAINING AT YOGA CENTRE WERE INCLUDED IN THE CONTROL GROUP. ALL THE PARTICIPANTS WERE TRAINED BY YOGA EXPERTS AND SUBJECTED TO REGULAR PRACTICE UNDER SUPERVISION FOR SIX MONTHS. IN ALL THE PARTICIPANTS FASTING (FBS) AND POST-PRANDIAL BLOOD SUGAR (PPBS) WAS ESTIMATED BEFORE, DURING (AT THREE MONTHS) AND AFTER (SIX MONTHS) YOGA TRAINING. PAIRED STUDENT T-TEST WAS USED TO ESTIMATE DIFFERENCE IN MEANS CALCULATED BEFORE AND AFTER YOGA TRAINING IN A SAME GROUP. A P-VALUE OF <0.05 WAS CONSIDERED AS STATISTICALLY SIGNIFICANT. RESULTS: THE DISTRIBUTION OF AGE, MEAN HEIGHT AND MEAN WEIGHT AMONG BOTH THE GROUPS WERE COMPARABLE. THE REDUCTION IN MEAN VALUES OF FBS AND PPBS AT THE END OF SIX MONTHS WAS HIGHLY SIGNIFICANT (P <0.001) IN BOTH THE GROUPS WHEN COMPARED WITH THE MEAN VALUES BEFORE AND DURING (THREE MONTHS) YOGA PRACTICE. THE REDUCTION IN THESE VALUES AT THREE MONTHS DURING YOGA WAS HIGHLY SIGNIFICANT IN T2DM GROUP WHEN COMPARED WITH MEAN VALUES BEFORE YOGA (P <0.001), BUT IT WAS INSIGNIFICANT (P<0.05) IN CONTROL GROUP. CONCLUSION: THE RESULTS OF THE PRESENT STUDY DEMONSTRATED THAT THE YOGA IS EFFECTIVE IN REDUCING THE BLOOD GLUCOSE LEVELS IN PATIENTS WITH T2DM.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                 
14 1322  34 HEMODYNAMIC AND PRESSOR RESPONSES TO COMBINATION OF YOGA AND BLOOD FLOW RESTRICTION. A COMBINATION OF YOGA AND BLOOD FLOW RESTRICTION, EACH OF WHICH ELICITS MARKED PRESSOR RESPONSES, MAY FURTHER INCREASE BLOOD PRESSURE AND MYOCARDIAL OXYGEN DEMAND. TO DETERMINE THE IMPACT OF A COMBINATION OF YOGA AND BLOOD FLOW RESTRICTION ON HEMODYNAMIC RESPONSES, TWENTY YOUNG HEALTHY PARTICIPANTS PERFORMED 20 YOGA POSES WITH/WITHOUT BLOOD FLOW RESTRICTION BANDS PLACED ON BOTH LEGS. AT BASELINE, THERE WERE NO SIGNIFICANT DIFFERENCES IN ANY OF THE VARIABLES BETWEEN THE BLOOD FLOW RESTRICTION AND NON-BLOOD FLOW RESTRICTION CONDITIONS. BLOOD PRESSURE AND HEART RATE INCREASED IN RESPONSE TO THE VARIOUS YOGA POSES (P<0.01) BUT WERE NOT DIFFERENT BETWEEN THE BLOOD FLOW RESTRICTION AND NON-BLOOD FLOW RESTRICTION CONDITIONS. RATE-PRESSURE PRODUCTS, AN INDEX OF MYOCARDIAL OXYGEN DEMAND, INCREASED SIGNIFICANTLY DURING YOGA EXERCISES WITH NO SIGNIFICANT DIFFERENCES BETWEEN THE TWO CONDITIONS. RATING OF PERCEIVED EXERTION WAS NOT DIFFERENT BETWEEN THE CONDITIONS. BLOOD LACTATE CONCENTRATION WAS SIGNIFICANTLY GREATER AFTER PERFORMING YOGA WITH BLOOD FLOW RESTRICTION BANDS (P=0.007). CARDIO-ANKLE VASCULAR INDEX, AN INDEX OF ARTERIAL STIFFNESS, DECREASED SIMILARLY AFTER YOGA EXERCISE IN BOTH CONDITIONS WHILE FLOW-MEDIATED DILATION REMAINED UNCHANGED. IN CONCLUSION, THE USE OF LOWER BODY BLOOD FLOW RESTRICTION BANDS IN COMBINATION WITH YOGA DID NOT RESULT IN ADDITIVE OR SYNERGISTIC HEMODYNAMIC AND PRESSOR RESPONSES.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
15 1261  36 FINGER DEXTERITY AND VISUAL DISCRIMINATION FOLLOWING TWO YOGA BREATHING PRACTICES. BACKGROUND: PRACTICING YOGA HAS BEEN SHOWN TO IMPROVE MOTOR FUNCTIONS AND ATTENTION. THOUGH ATTENTION IS REQUIRED FOR FINE MOTOR AND DISCRIMINATION TASKS, THE EFFECT OF YOGA BREATHING TECHNIQUES ON FINE MOTOR SKILLS AND VISUAL DISCRIMINATION HAS NOT BEEN ASSESSED. AIM: TO STUDY THE EFFECT OF YOGA BREATHING TECHNIQUES ON FINGER DEXTERITY AND VISUAL DISCRIMINATION. MATERIALS AND METHODS: THE PRESENT STUDY CONSISTED OF ONE HUNDRED AND FORTY SUBJECTS WHO HAD ENROLLED FOR STRESS MANAGEMENT. THEY WERE RANDOMLY DIVIDED INTO TWO GROUPS, ONE GROUP PRACTICED HIGH FREQUENCY YOGA BREATHING WHILE THE OTHER GROUP PRACTICED BREATH AWARENESS. HIGH FREQUENCY YOGA BREATHING (KAPALABHATI, BREATH RATE 1.0 HZ) AND BREATH AWARENESS ARE TWO YOGA PRACTICES WHICH IMPROVE ATTENTION. THE IMMEDIATE EFFECT OF HIGH FREQUENCY YOGA BREATHING AND BREATH AWARENESS (I) WERE ASSESSED ON THE PERFORMANCE ON THE O'CONNOR FINGER DEXTERITY TASK AND (II) (IN) A SHAPE AND SIZE DISCRIMINATION TASK. RESULTS: THERE WAS A SIGNIFICANT IMPROVEMENT IN THE FINGER DEXTERITY TASK BY 19% AFTER KAPALABHATI AND 9% AFTER BREATH AWARENESS (P<0.001 IN BOTH CASES, REPEATED MEASURES ANOVA AND POST-HOC ANALYSES). THERE WAS A SIGNIFICANT REDUCTION (P<0.001) IN ERROR (41% AFTER KAPALABHATI AND 21% AFTER BREATH AWARENESS) AS WELL AS TIME TAKEN TO COMPLETE THE SHAPE AND SIZE DISCRIMINATION TEST (15% AFTER KAPALABHATI AND 15% AFTER BREATH AWARENESS; P<0.001) WAS ALSO OBSERVED. CONCLUSION: BOTH KAPALABAHATI AND BREATH AWARENESS CAN IMPROVE FINE MOTOR SKILLS AND VISUAL DISCRIMINATION, WITH A GREATER MAGNITUDE OF CHANGE AFTER KAPALABHATI.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
16 2510  34 YOGA BREATHING THROUGH A PARTICULAR NOSTRIL INCREASES SPATIAL MEMORY SCORES WITHOUT LATERALIZED EFFECTS. UNINOSTRIL BREATHING FACILITATES THE PERFORMANCE ON SPATIAL AND VERBAL COGNITIVE TASKS, SAID TO BE RIGHT AND LEFT BRAIN FUNCTIONS, RESPECTIVELY. SINCE HEMISPHERIC MEMORY FUNCTIONS ARE ALSO KNOWN TO BE LATERALIZED, THE PRESENT STUDY ASSESSED THE EFFECTS OF UNINOSTRIL BREATHING ON THE PERFORMANCE IN VERBAL AND SPATIAL MEMORY TESTS. SCHOOL CHILDREN (N = 108 WHOSE AGES RANGED FROM 10 TO 17 YEARS) WERE RANDOMLY ASSIGNED TO FOUR GROUPS. EACH GROUP PRACTICED A SPECIFIC YOGA BREATHING TECHNIQUE: (I) RIGHT NOSTRIL BREATHING, (II) LEFT NOSTRIL BREATHING, (III) ALTERNATE NOSTRIL BREATHING, OR (IV) BREATH AWARENESS WITHOUT MANIPULATION OF NOSTRILS. THESE TECHNIQUES WERE PRACTICED FOR 10 DAYS. VERBAL AND SPATIAL MEMORY WAS ASSESSED INITIALLY AND AFTER 10 DAYS. AN AGE-MATCHED CONTROL GROUP OF 27 WERE SIMILARLY ASSESSED. ALL 4 TRAINED GROUPS SHOWED A SIGNIFICANT INCREASE IN SPATIAL TEST SCORES AT RETEST, BUT THE CONTROL GROUP SHOWED NO CHANGE. AVERAGE INCREASE IN SPATIAL MEMORY SCORES FOR THE TRAINED GROUPS WAS 84%. IT APPEARS YOGA BREATHING INCREASES SPATIAL RATHER THAN VERBAL SCORES, WITHOUT A LATERALIZED EFFECT.	1997	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
17  785  44 EFFECT OF YOGA BASED TECHNIQUES ON STRESS AND HEALTH INDICES USING ELECTRO PHOTONIC IMAGING TECHNIQUE IN MANAGERS. BACKGROUND: MEDITATION TECHNIQUES ARE KNOWN TO ELICIT RELAXATION RESPONSE IN WHICH MOVING MEDITATION WHICH COMBINES THE PRACTICE OF YOGA POSTURES AND GUIDED RELAXATION IS KNOWN AS CYCLIC MEDITATION REPORTED HELPFUL IN REDUCING THE SYMPATHETIC AROUSAL AND IMPROVING HEALTH OF PRACTITIONERS. OBJECTIVES: THE OBJECTIVE OF THIS STUDY WAS TO INVESTIGATE THE EFFECT OF CYCLIC MEDITATION ON STRESS AND HEALTH INDICES IN MANAGERS AS MEASURED BY ELECTRO PHOTONIC IMAGING (EPI) TECHNIQUE. MATERIALS AND METHODS: EPI TECHNIQUE WAS USED TO ASSESS PARTICIPANTS BEFORE AND AFTER 35 MIN OF CYCLIC MEDITATION (CM) AND EQUAL DURATION OF SUPINE REST (SR) SESSION. A TOTAL OF SIXTY SIX MALE MANAGERS, AGE RANGES FROM 35 TO 60 YEARS (MEAN +/- SD 53.97 +/- 5.96) WERE INCLUDED IN THE STUDY. EPI PARAMETERS, INCLUDING ACTIVATION COEFFICIENT, INTEGRAL AREA LEFT AND RIGHT AND INTEGRAL ENTROPY, LEFT AND RIGHT WERE TAKEN FOR STATISTICAL ANALYSES. RESULTS: CYCLIC MEDITATION HAS PRODUCED A HIGHLY SIGNIFICANT REDUCTION IN STRESS LEVEL, WHEREAS THIS REDUCTION WAS NOT FOUND SIGNIFICANT WITHIN SR GROUP. THERE WAS A SIGNIFICANT IMPROVEMENT IN HEALTH INDEX 'INTEGRAL AREA' VALUES IN BOTH LEFT AND RIGHT SIDES WITHIN THE CM GROUP WHILE ONLY IA RIGHT SIDE SHOWED A SIGNIFICANT IMPROVEMENT WITHIN THE CM GROUP. THE INTEGRAL ENTROPY VALUE RIGHT SIDE DECREASED SIGNIFICANTLY WITHIN THE CM GROUP, WHEREAS IE LEFT WAS FOUND DETERIORATED WITHIN THE SR GROUP. MOREOVER, ONLY IE LEFT SIDE HAS SHOWN A SIGNIFICANT DIFFERENCE BETWEEN THE GROUPS. CONCLUSION: THE INVESTIGATIONS IN THIS STUDY SUGGEST THAT CYCLIC MEDITATION PRACTICE REDUCES STRESS AND IMPROVES PSYCHOSOMATIC HEALTH INDICES MORE EFFECTIVELY THAN SUPINE REST IN MANAGERS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
18 1423  44 IMPROVEMENT IN NEUROCOGNITIVE FUNCTIONS AND SERUM BRAIN-DERIVED NEUROTROPHIC FACTOR LEVELS IN PATIENTS WITH DEPRESSION TREATED WITH ANTIDEPRESSANTS AND YOGA. CONTEXT AND AIMS: IMPAIRMENT IN COGNITION IS WELL-KNOWN IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER. THIS STUDY EXAMINED THE EFFECT OF YOGA THERAPY WITH OR WITHOUT ANTIDEPRESSANTS AND ANTIDEPRESSANTS ALONE ON CERTAIN NEUROPSYCHOLOGICAL FUNCTIONS IN PATIENTS WITH DEPRESSION. CORRELATION BETWEEN CHANGES IN NEUROPSYCHOLOGICAL TEST PERFORMANCE AND SERUM BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) LEVELS WAS ALSO EXPLORED. MATERIALS AND METHODS: ANTIDEPRESSANT-NAIVE/ANTIDEPRESSANT-FREE OUTPATIENTS WITH DEPRESSION RECEIVED ANTIDEPRESSANT MEDICATION ALONE (N = 23) OR YOGA THERAPY WITH (N = 26) OR WITHOUT (N = 16) ANTIDEPRESSANTS. DEPRESSION WAS ASSESSED USING THE HAMILTON DEPRESSION RATING SCALE. NEUROPSYCHOLOGICAL TESTS INCLUDED DIGIT-SPAN FORWARD AND BACKWARD, REY AUDITORY VERBAL LEARNING TEST, AND TRAIL MAKING TESTS (TMT-A AND B). THESE TESTS WERE ADMINISTERED BEFORE AND 3 MONTHS AFTER THE TREATMENT IN PATIENTS, AND ONCE IN HEALTHY COMPARISON SUBJECTS (N = 19). STATISTICAL ANALYSIS: BASELINE DIFFERENCES WERE ANALYZED USING INDEPENDENT SAMPLE T-TEST, CHI-SQUARE, AND ONE-WAY ANOVA. PAIRED T-TEST WAS USED TO ANALYZE THE CHANGE FROM BASELINE TO FOLLOW-UP. PEARSON'S CORRELATION WAS USED TO EXPLORE THE ASSOCIATION OF CHANGE BETWEEN 2 VARIABLES. RESULTS: PATIENTS HAD IMPAIRED PERFORMANCE ON MOST NEUROPSYCHOLOGICAL TESTS. AFTER 3 MONTHS, THERE WAS SIGNIFICANT IMPROVEMENT - PATIENTS' PERFORMANCE WAS COMPARABLE TO THAT OF HEALTHY CONTROLS ON MAJORITY OF THE TESTS. SIGNIFICANT INVERSE CORRELATION WAS OBSERVED BETWEEN INCREASE IN BDNF LEVELS AND IMPROVEMENT IN TMT "A" DURATION IN YOGA-ALONE GROUP (R = -0.647; P = 0.009). CONCLUSIONS: TO CONCLUDE THAT, YOGA THERAPY, ALONE OR IN COMBINATION WITH MEDICATIONS, IS ASSOCIATED WITH IMPROVED NEUROPSYCHOLOGICAL FUNCTIONS AND NEUROPLASTIC EFFECTS IN PATIENTS WITH DEPRESSION.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
19  716  46 EFFECT OF INTEGRATED YOGA PRACTICES ON IMMUNE RESPONSES IN EXAMINATION STRESS - A PRELIMINARY STUDY. BACKGROUND: STRESS IS OFTEN ASSOCIATED WITH AN INCREASED OCCURRENCE OF AUTONOMIC, CARDIOVASCULAR, AND IMMUNE SYSTEM PATHOLOGY. THIS STUDY WAS DONE TO EVALUATE THE IMPACT OF STRESS ON PSYCHOLOGICAL, PHYSIOLOGICAL PARAMETERS, AND IMMUNE SYSTEM DURING MEDICAL TERM -ACADEMIC EXAMINATION AND THE EFFECT OF YOGA PRACTICES ON THE SAME. MATERIALS AND METHODS: THE STUDY WAS CARRIED OUT ON SIXTY FIRST-YEAR MBBS STUDENTS RANDOMLY ASSIGNED TO YOGA GROUP AND CONTROL GROUP (30 EACH). THE YOGA GROUP UNDERWENT INTEGRATED YOGA PRACTICES FOR 35 MINUTES DAILY IN THE PRESENCE OF TRAINED YOGA TEACHER FOR 12 WEEKS. CONTROL GROUP DID NOT UNDERGO ANY KIND OF YOGA PRACTICE OR STRESS MANAGEMENT. PHYSIOLOGICAL PARAMETERS LIKE HEART RATE, RESPIRATORY RATE, AND BLOOD PRESSURE WERE MEASURED. GLOBAL ASSESSMENT OF RECENT STRESS SCALE AND SPIELBERGERS STATE ANXIETY SCORE WERE ASSESSED AT BASELINE AND DURING THE EXAMINATION. SERUM CORTISOL LEVELS, IL-4, AND IFN-GAMMA LEVELS WERE DETERMINED BY ENZYME-LINKED IMMUNOSORBENT ASSAY TECHNIQUE. RESULT: IN THE YOGA GROUP, NO SIGNIFICANT DIFFERENCE WAS OBSERVED IN PHYSIOLOGICAL PARAMETERS DURING THE EXAMINATION STRESS, WHEREAS IN THE CONTROL GROUP, A SIGNIFICANT INCREASE WAS OBSERVED. LIKEWISE, THE INDICATORS OF PSYCHOLOGICAL STRESS SHOWED HIGHLY SIGNIFICANT DIFFERENCE IN CONTROL GROUP COMPARED WITH SIGNIFICANT DIFFERENCE IN YOGA GROUP. DURING THE EXAMINATION, THE INCREASE IN SERUM CORTICAL AND DECREASE IN SERUM IFN-GAMMA IN YOGA GROUP WAS LESS SIGNIFICANT (P<0.01) THAN IN THE CONTROL GROUP (P<0.001). BOTH THE GROUPS DEMONSTRATED AN INCREASE IN SERUM IL-4 LEVELS, THE CHANGES BEING INSIGNIFICANT FOR THE DURATION OF THE STUDY. CONCLUSION: YOGA RESISTS THE AUTONOMIC CHANGES AND IMPAIRMENT OF CELLULAR IMMUNITY SEEN IN EXAMINATION STRESS.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
20  727  31 EFFECT OF LONG-TERM REGULAR YOGA ON PHYSICAL HEALTH OF YOGA PRACTITIONERS. BACKGROUND: YOGA IS A PHYSICAL, MENTAL, AND SPIRITUAL DISCIPLINE. THE EFFECT OF YOGA ON MENTAL HEALTH HAS BEEN STUDIED EXTENSIVELY IN INDIA BUT LESS IN THE CONTEXT OF PHYSICAL HEALTH. OBJECTIVE: THE OBJECTIVE WAS TO EXPLORE THE EFFECT OF LONG-TERM REGULAR YOGA ON PHYSICAL HEALTH OF YOGA PRACTITIONERS. MATERIALS AND METHODS: IT WAS AN INTERVENTIONAL STUDY. INCLUSION CRITERIA WERE STUDENTS WHO ENROLLED FOR 1-YEAR DIPLOMA COURSE AT THE YOGA CENTER. EXCLUSION CRITERIA WERE NONREGULAR YOGA PRACTITIONERS DURING THE COURSE. PHYSICAL HEALTH PARAMETERS CONSIDERED FOR ASSESSMENT BEFORE AND AFTER THE YOGA COURSE WERE PULMONARY FUNCTION TESTS, MAXIMUM OXYGEN CONSUMPTION (VO2 MAX) USING BRUCE TREADMILL TEST, FLEXIBILITY, BODY COMPOSITION ANALYSIS, AND HEMOGLOBIN LEVEL. PAIRED SAMPLE T-TEST AND CHI-SQUARE TEST WERE USED FOR STATISTICAL ANALYSIS. RESULTS: THE AEROBIC CAPACITY IMPROVED SIGNIFICANTLY IN TERMS OF MEAN (STANDARD DEVIATION [SD]) FORCED VITAL CAPACITY (P < 0.001), FORCED EXPIRATION VOLUME AT THE END OF THE FIRST SECOND (P < 0.001) AS WELL AS PEAK EXPIRATORY FLOW RATE (P = 0.04). THE MEAN (SD) FLEXIBILITY SCORE IMPROVED SIGNIFICANTLY (P < 0.001). SIMILARLY, THE ENDURANCE IMPROVED SIGNIFICANTLY IN TERMS OF MEAN (SD) VO2 MAX (< 0.001) AND TREADMILL TIME (P < 0.001). THERE WAS NO SIGNIFICANT CHANGE IN BODY COMPOSITION AND HEMOGLOBIN LEVEL. CONCLUSIONS: REGULAR YOGA PRACTITIONERS DEMONSTRATED THE IMPROVEMENT IN PULMONARY FUNCTIONS, CARDIORESPIRATORY FITNESS, ENDURANCE, AND FLEXIBILITY.	2021