1 1233 141 FEASIBILITY AND PRELIMINARY EFFICACY OF TAILORED YOGA IN SURVIVORS OF HEAD AND NECK CANCER: A PILOT STUDY. PURPOSE: TREATMENT FOR HEAD AND NECK CANCER (HNC) RESULTS IN LONG-TERM TOXICITIES AND INCREASED PHYSICAL AND PSYCHOSOCIAL SURVIVOR BURDEN. THERE ARE A LIMITED NUMBER OF TREATMENTS FOR THESE LATE EFFECTS. YOGA POSTURES, BREATH WORK, RELAXATION, AND MEDITATION, MAY IMPROVE THESE LATE EFFECTS. THE PURPOSE OF THIS STUDY WAS TO EXAMINE THE FEASIBILITY OF A TAILORED YOGA PROGRAM IN HNC SURVIVORS AND OBTAIN PRELIMINARY EFFICACY DATA. METHODS: THIS WAS A RANDOMIZED WAIT-LIST CONTROL STUDY OF YOGA-NAIVE HNC SURVIVORS WHO WERE >3 MONTHS POST-CANCER TREATMENT. BASELINE DATA WERE COLLECTED. PARTICIPANTS WERE RANDOMIZED TO EITHER AN 8-WEEK HATHA YOGA INTERVENTION GROUP OR A WAIT-LIST GROUP. FEASIBILITY AND EFFICACY DATA WERE COLLECTED. AT 4 AND 8 WEEKS, PATIENTS UNDERWENT A REPEAT ASSESSMENT OF HEALTH. WAIT-LIST CONTROL GROUP PARTICIPANTS WERE OFFERED THE YOGA PROGRAM AFTER DATA COLLECTION. DESCRIPTIVE STATISTICS EVALUATED FEASIBILITY. MIXED EFFECTS GENERAL LINEAR MODELS WERE USED TO GENERATE ESTIMATES OF THE EFFICACY OUTCOMES. RESULTS: SEVENTY-THREE INDIVIDUALS WERE SCREENED AND 40 WERE ELIGIBLE. ALL ELIGIBLE INDIVIDUALS CONSENTED AND ENROLLED. FIVE OF THE INTERVENTION GROUP DISCONTINUED EARLY AND NONE IN THE WAIT-LIST CONTROL GROUP. FEASIBILITY WAS AFFIRMED AS PARTICIPANTS WERE RECRUITED AND RETAINED IN THE STUDY, THERE WERE NO ADVERSE EVENTS, FIDELITY TO PROTOCOL WAS DEMONSTRATED, AND SATISFACTION RATES WERE HIGH. EFFICACY MEASURES INDICATED POTENTIAL BENEFIT FOR SHOULDER RANGE OF MOTION ( D = 0.57-0.86, P < .05), PAIN ( D = 0.67-0.90, P </= .005), AND ANXIETY ( D = 0.59, P = .015). CONCLUSION: A TAILORED HATHA YOGA PROGRAM IS FEASIBLE AND POTENTIALLY EFFICACIOUS FOR HNC SURVIVORS. PRELIMINARY DATA SUPPORTS FURTHER INVESTIGATION OF YOGA IN THIS POPULATION IS NEEDED.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
2 1242  42 FEASIBILITY OF A YOGA INTERVENTION TO DECREASE PAIN IN OLDER WOMEN: A RANDOMIZED CONTROLLED PILOT STUDY. BACKGROUND: A SIGNIFICANT PROPORTION OF OLDER WOMEN SUFFER FROM CHRONIC PAIN, WHICH CAN DECREASE QUALITY OF LIFE. THE OBJECTIVE OF THIS PILOT RANDOMIZED STUDY WAS TO EVALUATE THE FEASIBILITY OF A FLOW-RESTORATIVE YOGA INTERVENTION DESIGNED TO DECREASE PAIN AND RELATED OUTCOMES AMONG WOMEN AGED 60 OR OLDER. METHODS: FLOW-RESTORATIVE YOGA CLASSES WERE HELD TWICE WEEKLY FOR 1 HOUR AND LED BY A CERTIFIED YOGA INSTRUCTOR. PARTICIPANTS RANDOMIZED TO THE INTERVENTION GROUP ATTENDED THE YOGA CLASSES FOR 12 WEEKS AND RECEIVED SUPPLEMENTAL MATERIALS FOR AT-HOME PRACTICE. THOSE RANDOMIZED TO THE CONTROL GROUP WERE ASKED TO MAINTAIN THEIR NORMAL DAILY ROUTINE. FEASIBILITY WAS EVALUATED USING RECRUITMENT AND RETENTION RATES, CLASS AND HOME PRACTICE ADHERENCE RATES, AND PARTICIPANT SATISFACTION SURVEYS. OUTCOME MEASURES (SELF-REPORTED PAIN, INFLAMMATORY MARKERS, FUNCTIONAL FITNESS, QUALITY OF LIFE, RESILIENCE, AND SELF-REPORTED PHYSICAL ACTIVITY) WERE ASSESSED AT BASELINE AND POST-INTERVENTION. PAIRED T-TESTS OR WILCOXON SIGNED-RANK TESTS WERE USED TO EXAMINE CHANGES IN OUTCOME MEASURES WITHIN TREATMENT GROUPS. RESULTS: THIRTY-EIGHT PARTICIPANTS WERE RECRUITED AND RANDOMIZED. PARTICIPANTS WERE PRIMARILY WHITE, COLLEGE-EDUCATED, AND HIGHER FUNCTIONING, DESPITE EXPERIENCING VARIOUS FORMS OF CHRONIC PAIN. ATTENDANCE AND RETENTION RATES WERE HIGH (91 AND 97%, RESPECTIVELY) AND THE MAJORITY OF PARTICIPANTS WERE SATISFIED WITH THE YOGA PROGRAM (89%) AND WOULD RECOMMEND IT TO OTHERS (87%). INTERVENTION PARTICIPANTS ALSO EXPERIENCED REDUCTIONS IN PAIN INTERFERENCE AND IMPROVEMENTS IN ENERGY AND SOCIAL FUNCTIONING. CONCLUSIONS: THIS PILOT STUDY PROVIDES ESSENTIAL DATA TO INFORM A FULL SCALE RANDOMIZED TRIAL OF FLOW-RESTORATIVE YOGA FOR OLDER WOMEN WITH CHRONIC PAIN. FUTURE STUDIES SHOULD EMPHASIZE STRATEGIES TO RECRUIT A MORE DIVERSE STUDY POPULATION, PARTICULARLY OLDER WOMEN AT HIGHER RISK OF DISABILITY AND FUNCTIONAL DECLINE. TRIAL REGISTRATION: CLINICALTRIALS.GOV , NCT03790098 . REGISTERED 31 DECEMBER 2018 - RETROSPECTIVELY REGISTERED.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
3 2605  38 YOGA FOR PERSISTENT FATIGUE IN BREAST CANCER SURVIVORS: RESULTS OF A PILOT STUDY. APPROXIMATELY ONE-THIRD OF BREAST CANCER SURVIVORS EXPERIENCES PERSISTENT FATIGUE FOR MONTHS OR YEARS AFTER SUCCESSFUL TREATMENT COMPLETION. THERE IS A LACK OF EVIDENCE-BASED TREATMENTS FOR CANCER-RELATED FATIGUE, PARTICULARLY AMONG CANCER SURVIVORS. THIS SINGLE-ARM PILOT STUDY EVALUATED THE FEASIBILITY AND PRELIMINARY EFFICACY OF A YOGA INTERVENTION FOR FATIGUED BREAST CANCER SURVIVORS BASED ON THE IYENGAR TRADITION. IYENGAR YOGA PRESCRIBES SPECIFIC POSES FOR INDIVIDUALS WITH SPECIFIC MEDICAL PROBLEMS AND CONDITIONS; THIS TRIAL EMPHASIZED POSTURES BELIEVED TO BE EFFECTIVE FOR REDUCING FATIGUE AMONG BREAST CANCER SURVIVORS, INCLUDING INVERSIONS AND BACKBENDS PERFORMED WITH THE SUPPORT OF PROPS. TWELVE WOMEN WERE ENROLLED IN THE TRIAL, AND 11 COMPLETED THE FULL 12-WEEK COURSE OF TREATMENT. THERE WAS A SIGNIFICANT IMPROVEMENT IN FATIGUE SCORES FROM PRE- TO POST-INTERVENTION THAT WAS MAINTAINED AT THE 3-MONTH POST-INTERVENTION FOLLOWUP. SIGNIFICANT IMPROVEMENTS WERE ALSO OBSERVED IN MEASURES OF PHYSICAL FUNCTION, DEPRESSED MOOD, AND QUALITY OF LIFE. THESE RESULTS SUPPORT THE ACCEPTABILITY OF THIS INTERVENTION AND SUGGEST THAT IT MAY HAVE BENEFICIAL EFFECTS ON PERSISTENT POST-TREATMENT FATIGUE. HOWEVER, RESULTS REQUIRE REPLICATION IN A LARGER RANDOMIZED CONTROLLED TRIAL.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
4  428  38 CAN YOGA HAVE ANY EFFECT ON SHOULDER AND ARM PAIN AND QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER? A RANDOMIZED, CONTROLLED, SINGLE-BLIND TRIAL. OBJECTIVE: TO EXAMINE THE EFFECTS OF YOGA ON SHOULDER AND ARM PAIN, QUALITY OF LIFE (QOL), DEPRESSION, AND PHYSICAL PERFORMANCE IN PATIENTS WITH BREAST CANCER. METHODS: THIS PROSPECTIVE, RANDOMIZED STUDY INCLUDED 42 PATIENTS. THE PATIENTS IN GROUP 1 UNDERWENT A 10-WEEK HATHA YOGA EXERCISE PROGRAM. THE PATIENTS IN GROUP 2 WERE INCLUDED IN A 10-WEEK FOLLOW-UP PROGRAM. OUR PRIMARY ENDPOINT WAS ARM AND SHOULDER PAIN INTENSITY. RESULTS: THE GROUP RECEIVING YOGA SHOWED A SIGNIFICANT IMPROVEMENT IN THEIR PAIN SEVERITY FROM BASELINE TO POST-TREATMENT, AND THESE BENEFITS WERE MAINTAINED AT 2.5 MONTHS POST-TREATMENT. WHEN COMPARED TO THE CONTROL GROUP, THERE WERE NO STATISTICALLY SIGNIFICANT DIFFERENCES BETWEEN THE 2 GROUPS WITH RESPECT TO THE PARAMETERS ASSESSED AT THE END OF WEEK 10. CONCLUSION: YOGA WAS AN EFFECTIVE AND SAFE EXERCISE FOR ALLEVIATING SHOULDER AND ARM PAIN, WHICH IS A COMPLICATION WITH A HIGH PREVALENCE IN PATIENTS WITH BREAST CANCER.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
5 2579  30 YOGA FOR HEALTH-RELATED QUALITY OF LIFE IN ADULT CANCER: A RANDOMIZED CONTROLLED FEASIBILITY STUDY. AN INCREASE IN PATIENT-LED UPTAKE OF COMPLEMENTARY THERAPIES IN ADULT CANCER HAS LED TO A NEED FOR MORE RIGOROUS STUDY OF SUCH INTERVENTIONS AND THEIR OUTCOMES. THIS STUDY THEREFORE AIMED TO EVALUATE THE FEASIBILITY AND ACCEPTABILITY OF A YOGA INTERVENTION IN MEN AND WOMEN RECEIVING CONVENTIONAL TREATMENT FOR A CANCER DIAGNOSIS. PROSPECTIVE, MIXED METHODS FEASIBILITY TRIAL ALLOCATED PARTICIPANTS TO RECEIVE ONE OF THREE YOGA INTERVENTIONS OVER A FOUR-WEEK STUDY PERIOD. DATA COLLECTION WAS COMPLETED THROUGH ONLINE SURVEY OF QOL-CA/CS AND CUSTOMIZED SURVEYS. FIFTEEN PARTICIPANTS WERE INCLUDED (11 FEMALE) UNDERGOING TREATMENT FOR BREAST, PROSTATE, COLORECTAL, BRAIN, AND BLOOD AND LUNG CANCER. TWO PARTICIPANTS DROPPED OUT AND COMPLETE QUALITATIVE AND QUANTITATIVE DATA SETS WERE COLLECTED FROM 12 PARTICIPANTS AND FOUR YOGA INSTRUCTORS. OTHER OUTCOME MEASURES INCLUDED IMPLEMENTATION COSTS PATIENT-REPORTED PREFERENCES FOR YOGA INTERVENTION AND CHANGES IN QOL-CA/CS. THREE TYPES OF YOGA INTERVENTION WERE SAFELY ADMINISTERED IN ADULT CANCER. MIXED METHODS, COST-EFFICIENCY, QOL-CA/CS, AND EVIDENCE-BASED DESIGN OF YOGA INTERVENTION HAVE BEEN USED TO ESTABLISH FEASIBILITY AND PATIENT-PREFERENCES FOR YOGA DELIVERY IN ADULT CANER. RESULTS SUGGEST THAT, WITH SOME METHODOLOGICAL IMPROVEMENTS, A LARGE-SCALE RANDOMIZED CONTROLLED TRIAL IS WARRANTED TO TEST THE EFFICACY OF YOGA FOR MALE AND FEMALE CANCER PATIENTS. THIS TRIAL IS REGISTERED WITH CLINICALTRIALS.GOV NCT02309112.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
6 1243  54 FEASIBILITY OF A YOGA, AEROBIC AND STRETCHING-TONING EXERCISE PROGRAM FOR ADULT CANCER SURVIVORS: THE STAYFIT TRIAL. BACKGROUND: THE USE OF YOGA AS A MIND-BODY PRACTICE HAS BECOME INCREASINGLY POPULAR AMONG CLINICAL POPULATIONS AND OLDER ADULTS WHO USE THIS PRACTICE TO MANAGE AGE AND CHRONIC DISEASE-RELATED SYMPTOMS. ALTHOUGH YOGA CONTINUES TO GAIN POPULARITY AMONG PRACTITIONERS AND RESEARCHERS, PILOT STUDIES THAT EXAMINE ITS FEASIBILITY AND ACCEPTABILITY, ESPECIALLY AMONG CANCER SURVIVORS, ARE LIMITED. FEASIBILITY STUDIES PLAY A CRITICAL ROLE IN DETERMINING WHETHER THE TARGET POPULATION IS LIKELY TO ENGAGE WITH LARGER SCALE EFFICACY AND EFFECTIVENESS TRIALS. IN THIS PAPER WE PRESENT FEASIBILITY AND ACCEPTABILITY DATA FROM A 12-WEEK RANDOMIZED CONTROLLED TRIAL (RCT) CONDUCTED WITH ADULT CANCER SURVIVORS. METHODS: PARTICIPANTS N = 78 (MEAN AGE: 55 YEARS) WERE RANDOMIZED TO ONE OF THREE GROUPS: A HATHA YOGA, AEROBIC EXERCISE, OR STRETCHING-TONING CONTROL GROUP WITH GROUP EXERCISE CLASSES HELD FOR 150 MIN/WEEK FOR 12 WEEKS. HEREIN WE REPORT FEASIBILITY AND ACCEPTABILITY, INCLUDING ENROLLMENT RATES, ATTENDANCE, ATTRITION AND ADVERSE EVENTS, AND PARTICIPANT FEEDBACK AND SATISFACTION DATA. RESULTS: OF THE 233 ADULTS SCREENED, 109 WERE ELIGIBLE AND 78 RANDOMIZED TO ONE OF THE THREE INTERVENTION ARMS. SESSION ATTENDANCE WAS HIGH FOR ALL GROUPS (75.5-89.5%) AND 17 PARTICIPANTS DROPPED OUT DURING THE 12-WEEK INTERVENTION. PROGRAM SATISFACTION WAS HIGH (4.8 OR HIGHER OUT OF 5) AND NO ADVERSE EVENTS WERE REPORTED. ONE COHORT (N = 15) OF THE INTERVENTION TRANSITIONED TO REMOTE INTERVENTION DELIVERY DUE TO THE COVID-19 PANDEMIC. FEASIBILITY DATA FROM THESE PARTICIPANTS SUGGESTED THAT SYNCHRONIZED GROUP EXERCISE CLASSES VIA ZOOM WITH A LIVE INSTRUCTOR WERE ACCEPTABLE AND ENJOYABLE. PARTICIPANT FEEDBACK REGARDING MOST AND LEAST HELPFUL ASPECTS OF THE PROGRAM AS WELL AS SUGGESTIONS FOR FUTURE YOGA INTERVENTIONS ARE SUMMARIZED. CONCLUSIONS: OVERALL, THE YOGA INTERVENTION WAS HIGHLY FEASIBLE AND ACCEPTABLE. THE FEASIBILITY PARAMETERS FROM THIS TRIAL CAN AID RESEARCHERS IN ESTIMATING RECRUITMENT RATES FOR DESIRED SAMPLE SIZES TO SUCCESSFULLY RANDOMIZE AND RETAIN CANCER SURVIVORS IN SHORT- AND LONG-TERM YOGA-BASED EFFICACY AND EFFECTIVENESS TRIALS. THE FINDINGS ALSO PROVIDE EVIDENCE TO CLINICIANS WHO CAN RECOMMEND UP TO 150 MIN OF A COMBINATION OF EXERCISES-AEROBIC, YOGA, OR STRETCHING-TONING TO THEIR CANCER PATIENTS IN ORDER TO IMPROVE HEALTH AND WELLBEING DURING CANCER SURVIVORSHIP.	2021	
                                                                                                                                                       
7 2096  44 THE EFFECT OF YOGA EXERCISE ON IMPROVING DEPRESSION, ANXIETY, AND FATIGUE IN WOMEN WITH BREAST CANCER: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: DEPRESSION, ANXIETY, AND FATIGUE ARE AMONG THE MOST SIGNIFICANT PROBLEMS THAT INFLUENCE THE QUALITY OF LIFE OF PATIENTS WITH BREAST CANCER WHO RECEIVE ADJUVANT CHEMOTHERAPY. ALTHOUGH EVIDENCE HAS SHOWN YOGA TO DECREASE ANXIETY, DEPRESSION, AND FATIGUE IN PATIENTS WITH CANCER, FEW STUDIES ON THE EFFECTS OF YOGA HAVE TARGETED PATIENTS WITH BREAST CANCER. YOGA INTERVENTIONS SHOULD BE TESTED TO PROMOTE THE PSYCHOLOGICAL AND PHYSICAL HEALTH OF WOMEN WITH BREAST CANCER. PURPOSE: THIS STUDY EXAMINES THE EFFECTIVENESS OF AN 8-WEEK YOGA EXERCISE PROGRAM IN PROMOTING THE PSYCHOLOGICAL AND PHYSICAL HEALTH OF WOMEN WITH BREAST CANCER UNDERGOING ADJUVANT CHEMOTHERAPY IN TERMS OF DEPRESSION, ANXIETY, AND FATIGUE. METHODS: A SAMPLE OF 60 WOMEN WITH NONMETASTATIC BREAST CANCER WAS RECRUITED. PARTICIPANTS WERE RANDOMLY ASSIGNED INTO EITHER THE EXPERIMENTAL GROUP (N = 30) OR THE CONTROL GROUP (N = 30). A 60-MINUTE, TWICE-PER-WEEK YOGA EXERCISE WAS IMPLEMENTED FOR 8 WEEKS AS THE INTERVENTION FOR THE PARTICIPANTS IN THE EXPERIMENTAL GROUP. THE CONTROL GROUP RECEIVED STANDARD CARE ONLY. RESULTS: ANALYSIS USING THE JOHNSON-NEYMAN PROCEDURE FOUND THAT THE YOGA EXERCISE REDUCED OVERALL FATIGUE AND THE INTERFERENCE OF FATIGUE IN EVERYDAY LIFE FOR THE EXPERIMENTAL GROUP PARTICIPANTS. SIGNIFICANT REDUCTIONS WERE OBTAINED AFTER 4 WEEKS OF INTERVENTION PARTICIPATION FOR THOSE EXPERIMENTAL GROUP PATIENTS WITH RELATIVELY LOW STARTING BASELINE VALUES (BASELINE ITEM MEAN VALUE < 3.31 AND 3.22, RESPECTIVELY) AND AFTER 8 WEEKS FOR MOST PATIENTS (APPROXIMATELY 75%) WITH MODERATE STARTING BASELINE VALUES (BASELINE ITEM MEAN VALUE < 7.30 AND 5.34, RESPECTIVELY). THE 8-WEEK INTERVENTION DID NOT SIGNIFICANTLY IMPROVE THE LEVELS OF DEPRESSION (F = 1.29, P > .05) OR ANXIETY (F = 2.7, P > .05). CONCLUSIONS/IMPLICATIONS FOR PRACTICE: THE 8-WEEK YOGA EXERCISE PROGRAM DEVELOPED IN THIS STUDY EFFECTIVELY REDUCED FATIGUE IN PATIENTS WITH BREAST CANCER BUT DID NOT REDUCE DEPRESSION OR ANXIETY. ONCOLOGY NURSES SHOULD STRENGTHEN THEIR CLINICAL HEALTH EDUCATION AND APPLY YOGA TO REDUCE THE FATIGUE EXPERIENCED BY PATIENTS WITH BREAST CANCER WHO UNDERGO ADJUVANT CHEMOTHERAPY.	2014	
                                                                                                                                                                                                                                                                                                                                                                 
8 1564  53 LONGITUDINAL IMPACT OF YOGA ON CHEMOTHERAPY-RELATED COGNITIVE IMPAIRMENT AND QUALITY OF LIFE IN WOMEN WITH EARLY STAGE BREAST CANCER: A CASE SERIES. PURPOSE: ADJUVANT CHEMOTHERAPY FOR WOMEN WITH BREAST CANCER HAS SIGNIFICANTLY IMPROVED THE CURE RATE; HOWEVER, IT HAS BEEN ASSOCIATED WITH CHEMOTHERAPY-RELATED COGNITIVE IMPACT (CRCI). THE LITERATURE PROVIDES PRELIMINARY SUPPORT FOR THE FEASIBILITY AND EFFICACY OF YOGA INTERVENTIONS FOR THE GENERAL CANCER POPULATION, HOWEVER, CONTROLLED TRIALS ARE SCARCE AND NO STUDIES HAVE EXAMINED THE EFFECT OF YOGA ON COGNITION FOR WOMEN WITH BREAST CANCER DURING CHEMOTHERAPY. THIS CASE SERIES AIMS TO IDENTIFY THE IMPACT OF YOGA ON MEASURES OF COGNITION, FUNCTIONAL OUTCOMES, AND QUALITY OF LIFE (QOL) FOR BREAST CANCER SURVIVORS (BCS). METHODS: FOUR WOMEN WITH A DIAGNOSIS OF EARLY-STAGE BREAST CANCER PRIOR TO CHEMOTHERAPY TREATMENT WERE ADMINISTERED THE FOLLOWING PHYSIOLOGIC MEASURES AT BASELINE, 6, AND 12 WEEKS DURING CHEMOTHERAPY, AND AT ONE AND THREE MONTHS AFTER THE CONCLUSION OF THE STUDY: FUNCTIONAL REACH TEST (BALANCE) AND SIT AND REACH TEST (FLEXIBILITY), AND QOL, POMS (MOOD) AND FACT-B (QOL), AT BASELINE. PRIMARY OUTCOMES OF COGNITION WERE MEASURED WITH THE PERCEIVED COGNITION QUESTIONNAIRE (PCQ) AND COGSTATE, A COMPUTERIZED MEASUREMENT OF COGNITION. WOMEN ATTENDED AN IYENGAR-INSPIRED YOGA PROGRAM TWICE A WEEK FOR 12 WEEKS. QUALITATIVE QUESTIONNAIRES WERE ADMINISTERED AFTER THE COMPLETION OF THE STUDY TO DETERMINE PERCEIVED BENEFITS AND CHALLENGES OF THE YOGA PROGRAM. RESULTS: FOUR WOMEN WITH STAGE II BREAST CANCER RANGED IN AGE FROM 44-65 YEARS. COGSTATE COMPUTERIZED TESTING SHOWED CHANGES IN VARYING DOMAINS OF COGNITION THROUGH TREATMENT AND FOLLOW-UP. IMPROVED BALANCE, FLEXIBILITY, AND QOL WERE ALSO NOTED OVER TIME. NO ADVERSE EVENTS WERE OBSERVED. ANALYSIS OF QUALITATIVE DATA REVEALED THE YOGA CLASSES WERE HELPFUL AND SUBJECTS CONTINUED THE PRACTICE ELEMENTS OF YOGA INCLUDING RELAXATION, BREATHING, AND STRETCHING. THE MOST CHALLENGING ASPECT OF THE STUDY WAS PHYSICAL LIMITATIONS DUE TO VARIOUS MEDICAL COMPLICATIONS AND INCLUDED FATIGUE, DECREASED RANGE OF MOTION, AND PAIN. CONCLUSION: THIS CASE SERIES SUGGESTS THAT YOGA MAY IMPACT VARIOUS ASPECTS OF COGNITION DURING AND AFTER CHEMOTHERAPY ADMINISTRATION AS NOTED THROUGH QUANTITATIVE MEASURES. WOMEN DESCRIBE YOGA AS IMPROVING VARIOUS DOMAINS OF QOL THROUGH THE TREATMENT TRAJECTORY. THIS MIND-BODY INTERVENTION MAY STAVE OFF CRCI; HOWEVER, FURTHER INVESTIGATION IS NEEDED FOR ADDITIONAL RANDOMIZED CONTROLLED TRIALS ON THE EFFECTS OF YOGA ON COGNITION FOR WOMEN WITH BREAST CANCER UNDERGOING ADJUVANT CHEMOTHERAPY TREATMENT.	2012	

9  115  35 A PILOT STUDY OF A YOGA INTERVENTION FOR THE TREATMENT OF ANXIETY IN YOUNG PEOPLE WITH EARLY PSYCHOSIS. BACKGROUND: ANXIETY IS COMMON IN YOUNG PEOPLE WITH EARLY PSYCHOSIS AND TREATMENT OPTIONS FOR THIS CO-MORBIDITY REMAIN LIMITED. YOGA IS A PROMISING ADJUNCT INTERVENTION THAT HAS BEEN SHOWN TO REDUCE ANXIETY FOR ADULTS WITH SCHIZOPHRENIA, THEREFORE THIS PILOT STUDY EVALUATED THE ACCEPTABILITY AND POTENTIAL EFFECTIVENESS OF YOGA FOR ANXIETY IN EARLY PSYCHOSIS. METHODS: A PROSPECTIVE SINGLE ARM PILOT STUDY OF A YOGA INTERVENTION WAS CONDUCTED WITHIN AN EARLY INTERVENTION FOR PSYCHOSIS SERVICE. RATES OF ATTENDANCE, AS WELL AS SYMPTOMS OF ANXIETY PRE AND POST YOGA SESSION WERE MEASURED. RESULTS: A TOTAL OF 14 YOUNG PEOPLE PARTICIPATED IN THE STUDY AND OVER 70% ATTENDED HALF OR MORE OF THE YOGA SESSIONS OFFERED. SIGNIFICANT TRANSIENT REDUCTION IN STATE ANXIETY AFTER A SINGLE SESSION OF YOGA WAS OBSERVED (P < 0.01). CONCLUSIONS: YOGA WAS FOUND TO BE AN ACCEPTABLE AND POTENTIALLY EFFECTIVE ADJUNCTIVE TREATMENT FOR ANXIETY IN EARLY PSYCHOSIS AND THE RESULTS WARRANT FURTHER CLINICAL TRIALS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
10 2222  54 THE IMPACT OF MODIFIED HATHA YOGA ON CHRONIC LOW BACK PAIN: A PILOT STUDY. PURPOSE: THE PURPOSE OF THIS RANDOMIZED PILOT STUDY WAS TO EVALUATE A POSSIBLE DESIGN FOR A 6-WEEK MODIFIED HATHA YOGA PROTOCOL TO STUDY THE EFFECTS ON PARTICIPANTS WITH CHRONIC LOW BACK PAIN. PARTICIPANTS: TWENTY-TWO PARTICIPANTS (M = 4; F = 17), BETWEEN THE AGES OF 30 AND 65, WITH CHRONIC LOW BACK PAIN (CLBP) WERE RANDOMIZED TO EITHER AN IMMEDIATE YOGA BASED INTERVENTION, OR TO A CONTROL GROUP WITH NO TREATMENT DURING THE OBSERVATION PERIOD BUT RECEIVED LATER YOGA TRAINING. METHODS: A SPECIFIC CLBP YOGA PROTOCOL DESIGNED AND MODIFIED FOR THIS POPULATION BY A CERTIFIED YOGA INSTRUCTOR WAS ADMINISTERED FOR ONE HOUR, TWICE A WEEK FOR 6 WEEKS. PRIMARY FUNCTIONAL OUTCOME MEASURES INCLUDED THE FORWARD REACH (FR) AND SIT AND REACH (SR) TESTS. ALL PARTICIPANTS COMPLETED OSWESTRY DISABILITY INDEX (ODI) AND BECK DEPRESSION INVENTORY (BDI) QUESTIONNAIRES. GUIDING QUESTIONS WERE USED FOR QUALITATIVE DATA ANALYSIS TO ASCERTAIN HOW YOGA PARTICIPANTS PERCEIVED THE INSTRUCTOR, GROUP DYNAMICS, AND THE IMPACT OF YOGA ON THEIR LIFE. ANALYSIS: TO ACCOUNT FOR DROP OUTS, THE DATA WERE DIVIDED INTO BETTER OR NOT CATEGORIES, AND ANALYZED USING CHI-SQUARE TO EXAMINE DIFFERENCES BETWEEN THE GROUPS. QUALITATIVE DATA WERE ANALYZED THROUGH FREQUENCY OF POSITIVE RESPONSES. RESULTS: POTENTIALLY IMPORTANT TRENDS IN THE FUNCTIONAL MEASUREMENT SCORES SHOWED IMPROVED BALANCE AND FLEXIBILITY AND DECREASED DISABILITY AND DEPRESSION FOR THE YOGA GROUP BUT THIS PILOT WAS NOT POWERED TO REACH STATISTICAL SIGNIFICANCE. SIGNIFICANT LIMITATIONS INCLUDED A HIGH DROPOUT RATE IN THE CONTROL GROUP AND LARGE BASELINE DIFFERENCES IN THE SECONDARY MEASURES. IN ADDITION, ANALYSIS OF THE QUALITATIVE DATA REVEALED THE FOLLOWING FREQUENCY OF RESPONSES (1) GROUP INTERVENTION MOTIVATED THE PARTICIPANTS AND (2) YOGA FOSTERED RELAXATION AND NEW AWARENESS/LEARNING. CONCLUSION: A MODIFIED YOGA-BASED INTERVENTION MAY BENEFIT INDIVIDUALS WITH CLB, BUT A LARGER STUDY IS NECESSARY TO PROVIDE DEFINITIVE EVIDENCE. ALSO, THE IMPACT ON DEPRESSION AND DISABILITY COULD BE CONSIDERED AS IMPORTANT OUTCOMES FOR FURTHER STUDY. ADDITIONAL FUNCTIONAL OUTCOME MEASURES SHOULD BE EXPLORED. THIS PILOT STUDY SUPPORTS THE NEED FOR MORE RESEARCH INVESTIGATING THE EFFECT OF YOGA FOR THIS POPULATION.	2004	
                                                                                                                                                                                                                                                                                                                                     
11 1267  39 FOLLOW-UP OF YOGA OF AWARENESS FOR FIBROMYALGIA: RESULTS AT 3 MONTHS AND REPLICATION IN THE WAIT-LIST GROUP. OBJECTIVES: PUBLISHED PRELIMINARY FINDINGS FROM A RANDOMIZED-CONTROLLED TRIAL SUGGEST THAT AN 8-WEEK YOGA OF AWARENESS INTERVENTION MAY BE EFFECTIVE FOR IMPROVING SYMPTOMS, FUNCTIONAL DEFICITS, AND COPING ABILITIES IN FIBROMYALGIA. THE PRIMARY AIMS OF THIS STUDY WERE TO EVALUATE THE SAME INTERVENTION'S POSTTREATMENT EFFECTS IN A WAIT-LIST GROUP AND TO TEST THE INTERVENTION'S EFFECTS AT 3-MONTH FOLLOW-UP IN THE IMMEDIATE TREATMENT GROUP. METHODS: UNPAIRED T TESTS WERE USED TO COMPARE DATA FROM A PER PROTOCOL SAMPLE OF 21 WOMEN IN THE IMMEDIATE TREATMENT GROUP WHO HAD COMPLETED TREATMENT AND 18 WOMEN IN THE WAIT-LIST GROUP WHO HAD COMPLETED TREATMENT. WITHIN-GROUP PAIRED T TESTS WERE PERFORMED TO COMPARE POSTTREATMENT DATA WITH 3-MONTH FOLLOW-UP DATA IN THE IMMEDIATE TREATMENT GROUP. THE PRIMARY OUTCOME MEASURE WAS THE FIBROMYALGIA IMPACT QUESTIONNAIRE REVISED (FIQR). MULTILEVEL RANDOM-EFFECTS MODELS WERE ALSO USED TO EXAMINE ASSOCIATIONS BETWEEN YOGA PRACTICE RATES AND OUTCOMES. RESULTS: POSTTREATMENT RESULTS IN THE WAIT-LIST GROUP LARGELY MIRRORED RESULTS SEEN AT POSTTREATMENT IN THE IMMEDIATE TREATMENT GROUP, WITH THE FIQR TOTAL SCORE IMPROVING BY 31.9% ACROSS THE 2 GROUPS. FOLLOW-UP RESULTS SHOWED THAT PATIENTS SUSTAINED MOST OF THEIR POSTTREATMENT GAINS, WITH THE FIQR TOTAL SCORE REMAINING 21.9% IMPROVED AT 3 MONTHS. YOGA PRACTICE RATES WERE GOOD, AND MORE PRACTICE WAS ASSOCIATED WITH MORE BENEFIT FOR A VARIETY OF OUTCOMES. DISCUSSION: THESE FINDINGS INDICATE THAT THE BENEFITS OF YOGA OF AWARENESS IN FIBROMYALGIA ARE REPLICABLE AND CAN BE MAINTAINED.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
12 1106  41 EFFECTS OF YOGA, AEROBIC, AND STRETCHING AND TONING EXERCISES ON COGNITION IN ADULT CANCER SURVIVORS: PROTOCOL OF THE STAY FIT PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: CANCER SURVIVORS EXPERIENCE COMPROMISED QUALITY OF LIFE DUE TO IMPAIRED COGNITIVE FUNCTION AS A RESULT OF CANCER DIAGNOSIS AND TREATMENT. ALTHOUGH EXERCISE HAS PROVEN TO BE EFFECTIVE IN IMPROVING COGNITIVE FUNCTION ACROSS THE LIFESPAN, INTERVENTIONS COMPREHENSIVELY TESTING THE EFFECTIVENESS FOR CANCER SURVIVORS ARE LIMITED. THE STAY FIT TRIAL IS A THREE-ARMED PILOT RANDOMIZED CONTROLLED TRIAL DESIGNED TO COMPARE THE EFFECTS OF A 12-WEEK YOGA, AEROBIC WALKING, AND STRETCH AND TONE INTERVENTION ON COGNITIVE FUNCTION AMONG ADULT CANCER SURVIVORS. METHODS: THIS PILOT STUDY AIMS TO RECRUIT 75 ADULT CANCER SURVIVORS WHO WILL COMPLETE ASSESSMENTS OF COGNITIVE FUNCTION, CARDIOVASCULAR FITNESS, PHYSICAL ACTIVITY, AND PSYCHOSOCIAL MEASURES AT BASELINE AND AFTER THE 12-WEEK INTERVENTION. THE AIMS OF STAY FIT ARE (1) TO ASSESS THE EFFICACY OF YOGA TO IMPROVE COGNITIVE FUNCTION AMONG CANCER SURVIVORS, COMPARED TO AEROBIC EXERCISE AND AN ACTIVE CONTROL GROUP; (2) TO EXAMINE CHANGES IN CARDIOVASCULAR FITNESS AS A RESULT OF THE INTERVENTIONS; AND (3) TO ASSESS CHANGES IN QUALITY OF LIFE AMONG OUR POPULATION AS A RESULT OF THE EXERCISE INTERVENTIONS. DISCUSSION: THE STAY FIT TRIAL WILL TEST THE EFFECTIVENESS OF YOGA, AEROBIC EXERCISE, AND STRETCHING AND TONING EXERCISES IN IMPROVING COGNITIVE FUNCTION AND FITNESS AMONG ADULT CANCER SURVIVORS. THE RESULTS OF THIS PILOT STUDY WILL ENABLE US TO UNDERSTAND THE MOST EFFECTIVE PHYSICAL ACTIVITY MODALITY TO IMPROVE COGNITIVE FUNCTION IN THIS POPULATION AND POTENTIALLY COMBAT CANCER-RELATED COGNITIVE IMPAIRMENT. TRIAL REGISTRATION: CLINICALTRIALS.GOV NCT03650322 . REGISTERED ON 28 AUGUST 2018.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
13  112  35 A PILOT STUDY OF A MINDFULNESS INFORMED YOGA INTERVENTION IN YOUNG PEOPLE WITH PSYCHOSIS. AIM: TO DETERMINE THE ACCEPTABILITY AND SAFETY OF A MINDFULNESS INFORMED YOGA INTERVENTION AS ADJUNCT TO USUAL CARE FOR YOUNG PEOPLE WITH EARLY PSYCHOSIS. METHODS: PEOPLE AGED 16-25 YEARS ATTENDING A COMMUNITY-BASED SPECIALIST EARLY PSYCHOSIS CLINIC WERE INVITED TO PARTICIPATE IN A 12-WEEK YOGA INTERVENTION. THE INTERVENTION CONSISTED OF 1-H WEEKLY CLASSES OF MINDFULNESS INFORMED YOGA. ACCEPTABILITY WAS MEASURED BY UPTAKE, ATTENDANCE AND PARTICIPANTS' SATISFACTION. SAFETY WAS MEASURED BY INCIDENCE OF PHYSICAL INJURY, PARTICIPANTS' LEVEL OF COMFORT, DISTRESS AND ANXIETY DURING THE SESSIONS, AND THE FOLLOWING MENTAL HEALTH OUTCOMES: POSITIVE AND NEGATIVE PSYCHOTIC, DEPRESSION, ANXIETY AND STRESS SYMPTOMS, SLEEP QUALITY AND FUNCTIONING. RESULTS: OF THOSE WHO CONSENTED TO THE STUDY, 80% (12) PARTICIPATED AND ON AVERAGE ATTENDED 4.4 YOGA CLASSES. THERE WERE NO PHYSICAL INJURIES AND PARTICIPANTS REPORTED MINIMAL DISTRESS AND ANXIETY. POST-INTERVENTION, THERE WAS A SIGNIFICANT REDUCTION IN ANXIETY SYMPTOMS AND AN IMPROVEMENT IN FUNCTION. CONCLUSIONS: MINDFULNESS-BASED YOGA INTERVENTIONS ARE BOTH ACCEPTABLE AND SAFE AS AN INTERVENTION FOR YOUTH WITH EARLY PSYCHOSIS. THOUGH NUMBERS WERE SMALL, THE STUDY SHOWS PROMISE FOR YOGA AS A POTENTIALLY USEFUL INTERVENTION. IMPORTANTLY, THERE WAS NO DETERIORATION IN MENTAL HEALTH OUTCOMES. A LARGER TRIAL EVALUATING CLINICAL EFFECTIVENESS IS NOW TIMELY.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
14 2508  41 YOGA BREATHING FOR CANCER CHEMOTHERAPY-ASSOCIATED SYMPTOMS AND QUALITY OF LIFE: RESULTS OF A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: MANY DEBILITATING SYMPTOMS ARISE FROM CANCER AND ITS TREATMENT THAT ARE OFTEN UNRELIEVED BY ESTABLISHED METHODS. PRANAYAMA, A SERIES OF YOGIC BREATHING TECHNIQUES, MAY IMPROVE CANCER-RELATED SYMPTOMS AND QUALITY OF LIFE, BUT IT HAS NOT BEEN STUDIED FOR THIS PURPOSE. OBJECTIVES: A PILOT STUDY WAS PERFORMED TO EVALUATE FEASIBILITY AND TO TEST THE EFFECTS OF PRANAYAMA ON CANCER-ASSOCIATED SYMPTOMS AND QUALITY OF LIFE. DESIGN: THIS WAS A RANDOMIZED CONTROLLED CLINICAL TRIAL COMPARING PRANAYAMA TO USUAL CARE. SETTING: THE STUDY WAS CONDUCTED AT A UNIVERSITY MEDICAL CENTER. SUBJECTS: PATIENTS RECEIVING CANCER CHEMOTHERAPY WERE RANDOMIZED TO RECEIVE PRANAYAMA IMMEDIATELY OR AFTER A WAITING PERIOD (CONTROL GROUP). INTERVENTIONS: THE PRANAYAMA INTERVENTION CONSISTED OF FOUR BREATHING TECHNIQUES TAUGHT IN WEEKLY CLASSES AND PRACTICED AT HOME. THE TREATMENT GROUP RECEIVED PRANAYAMA DURING TWO CONSECUTIVE CYCLES OF CHEMOTHERAPY. THE CONTROL GROUP RECEIVED USUAL CARE DURING THEIR FIRST CYCLE, AND RECEIVED PRANAYAMA DURING THEIR SECOND CYCLE OF CHEMOTHERAPY. OUTCOME MEASURES: FEASIBILITY, CANCER-ASSOCIATED SYMPTOMS (FATIGUE, SLEEP DISTURBANCE, ANXIETY, DEPRESSION, STRESS), AND QUALITY OF LIFE WERE THE OUTCOMES. RESULTS: CLASS ATTENDANCE WAS NEARLY 100% IN BOTH GROUPS. SIXTEEN (16) PARTICIPANTS WERE INCLUDED IN THE FINAL INTENT-TO-TREAT ANALYSES. THE REPEATED-MEASURES ANALYSES DEMONSTRATED THAT ANY INCREASE IN PRANAYAMA DOSE, WITH DOSE MEASURED IN THE NUMBER OF HOURS PRACTICED IN CLASS OR AT HOME, RESULTED IN IMPROVED SYMPTOM AND QUALITY-OF-LIFE SCORES. SEVERAL OF THESE ASSOCIATIONS--SLEEP DISTURBANCE (P=0.04), ANXIETY (P=0.04), AND MENTAL QUALITY OF LIFE (P=0.05)--REACHED OR APPROACHED STATISTICAL SIGNIFICANCE. CONCLUSIONS: YOGA BREATHING WAS A FEASIBLE INTERVENTION AMONG PATIENTS WITH CANCER RECEIVING CHEMOTHERAPY. PRANAYAMA MAY IMPROVE SLEEP DISTURBANCE, ANXIETY, AND MENTAL QUALITY OF LIFE. A DOSE-RESPONSE RELATIONSHIP WAS FOUND BETWEEN PRANAYAMA USE AND IMPROVEMENTS IN CHEMOTHERAPY-ASSOCIATED SYMPTOMS AND QUALITY OF LIFE. THESE FINDINGS NEED TO BE CONFIRMED IN A LARGER STUDY.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                 
15 2628  46 YOGA FOR THE MANAGEMENT OF PAIN AND SLEEP IN RHEUMATOID ARTHRITIS: A PILOT RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: THE AIM OF THE PRESENT STUDY WAS TO DETERMINE THE FEASIBILITY OF A RELAXATION-BASED YOGA INTERVENTION FOR RHEUMATOID ARTHRITIS, DESIGNED AND REPORTED IN ACCORDANCE WITH DELPHI RECOMMENDATIONS FOR YOGA INTERVENTIONS FOR MUSCULOSKELETAL CONDITIONS. METHODS: PARTICIPANTS WERE RECRUITED FROM A HOSPITAL DATABASE, AND RANDOMIZED TO EITHER EIGHT WEEKLY 75-MIN YOGA CLASSES OR A USUAL CARE CONTROL. FEASIBILITY WAS DETERMINED BY RECRUITMENT RATES, RETENTION, PROTOCOL ADHERENCE, PARTICIPANT SATISFACTION AND ADVERSE EVENTS. SECONDARY PHYSICAL AND PSYCHOSOCIAL OUTCOMES WERE ASSESSED USING SELF-REPORTED QUESTIONNAIRES AT BASELINE (WEEK 0), WEEK 9 (PRIMARY TIME POINT) AND WEEK 12 (FOLLOW-UP). RESULTS: OVER A 3-MONTH PERIOD, 26 PARTICIPANTS WITH MILD PAIN, MILD TO MODERATE FUNCTIONAL DISABILITY AND MODERATE DISEASE ACTIVITY WERE RECRUITED INTO THE STUDY (25% RECRUITMENT RATE). RETENTION RATES WERE 100% FOR YOGA PARTICIPANTS AND 92% FOR USUAL CARE PARTICIPANTS AT BOTH WEEKS 9 AND 12. PROTOCOL ADHERENCE AND PARTICIPANT SATISFACTION WERE HIGH. YOGA PARTICIPANTS ATTENDED A MEDIAN OF SEVEN CLASSES; ADDITIONALLY, SEVEN OF THE YOGA PARTICIPANTS (54%) REPORTED CONTINUING YOGA AT HOME DURING THE FOLLOW-UP PERIOD. NO SERIOUS ADVERSE EVENTS WERE RELATED TO THE STUDY. SECONDARY OUTCOMES SHOWED NO GROUP EFFECTS OF YOGA COMPARED WITH USUAL CARE. CONCLUSIONS: A RELAXATION-BASED YOGA PROGRAMME WAS FOUND TO BE FEASIBLE AND SAFE FOR PARTICIPANTS WITH RHEUMATOID ARTHRITIS-RELATED PAIN AND FUNCTIONAL DISABILITY. ADVERSE EVENTS WERE MINOR, AND NOT UNEXPECTED FROM AN INTERVENTION INCLUDING PHYSICAL COMPONENTS. THIS PILOT PROVIDES A FRAMEWORK FOR LARGER INTERVENTION STUDIES, AND SUPPORTS FURTHER EXPLORATION OF YOGA AS A COMPLEX INTERVENTION TO ASSIST WITH THE MANAGEMENT OF RHEUMATOID ARTHRITIS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
16 1901  40 RESTORATIVE YOGA FOR WOMEN WITH OVARIAN OR BREAST CANCER: FINDINGS FROM A PILOT STUDY. YOGA HAS DEMONSTRATED BENEFIT IN HEALTHY INDIVIDUALS AND THOSE WITH VARIOUS HEALTH CONDITIONS. THERE ARE, HOWEVER, FEW SYSTEMATIC STUDIES TO SUPPORT THE DEVELOPMENT OF YOGA INTERVENTIONS FOR CANCER PATIENTS. RESTORATIVE YOGA (RY) IS A GENTLE TYPE OF YOGA THAT HAS BEEN DESCRIBED AS "ACTIVE RELAXATION." THE SPECIFIC AIMS OF THIS PILOT STUDY WERE TO DETERMINE THE FEASIBILITY OF IMPLEMENTING AN RY INTERVENTION AS A SUPPORTIVE THERAPY FOR WOMEN DIAGNOSED WITH OVARIAN OR BREAST CANCER AND TO MEASURE CHANGES IN SELF-REPORTED FATIGUE, PSYCHOLOGICAL DISTRESS AND WELL-BEING, AND QUALITY OF LIFE. FIFTY-ONE WOMEN WITH OVARIAN (N = 37) OR BREAST CANCER (N = 14) WITH A MEAN AGE OF 58.9 YEARS ENROLLED IN THIS STUDY; THE MAJORITY (61%) WERE ACTIVELY UNDERGOING CANCER TREATMENT AT THE TIME OF ENROLLMENT. ALL STUDY PARTICIPANTS PARTICIPATED IN 10 WEEKLY 75-MINUTE RY CLASSES THAT COMBINED PHYSICAL POSTURES, BREATHING, AND DEEP RELAXATION. STUDY PARTICIPANTS COMPLETED QUESTIONNAIRES AT BASELINE, IMMEDIATELY POSTINTERVENTION, AND 2 MONTHS POSTINTERVENTION. SIGNIFICANT IMPROVEMENTS WERE SEEN FOR DEPRESSION, NEGATIVE AFFECT, STATE ANXIETY, MENTAL HEALTH, AND OVERALL QUALITY OF LIFE. FATIGUE DECREASED BETWEEN BASELINE AND POSTINTERVENTION FOLLOW-UP. HEALTH-RELATED QUALITY OF LIFE IMPROVED BETWEEN BASELINE AND THE 2-MONTH FOLLOW-UP. QUALITATIVE FEEDBACK FROM PARTICIPANTS WAS PREDOMINANTLY POSITIVE; RELAXATION AND SHARED GROUP EXPERIENCE WERE TWO COMMON THEMES.	2008	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
17 2673  31 YOGA IN PRIMARY HEALTH CARE: A QUASI-EXPERIMENTAL STUDY TO ACCESS THE EFFECTS ON QUALITY OF LIFE AND PSYCHOLOGICAL DISTRESS. BACKGROUND: AND PURPOSE: YOGA IS GROWING IN POPULARITY, BUT ITS BENEFITS AND INTEGRATION INTO PRIMARY CARE REMAIN UNCERTAIN. HERE, WE DETERMINE YOGA EFFECTS ON QUALITY OF LIFE AND PSYCHOLOGICAL DISTRESS, AND EVALUATE THE FEASIBILITY OF INTRODUCING YOGA AT PRIMARY CARE LEVEL. MATERIALS AND METHODS: THIS IS A PROSPECTIVE, LONGITUDINAL, QUASI-EXPERIMENTAL STUDY, WITH AN INTERVENTION (N=49) AND A CONTROL GROUP (N=37). YOGA GROUP UNDERWENT 24-WEEKS PROGRAM OF ONE-HOUR SESSIONS. OUR PRIMARY ENDPOINT WAS QUALITY OF LIFE AND PSYCHOLOGICAL DISTRESS, AS WELL AS SATISFACTION LEVEL AND ADHERENCE RATE. RESULTS: PARTICIPANTS REPORTED A SIGNIFICANT IMPROVEMENT IN ALL DOMAINS OF QUALITY OF LIFE AND A REDUCTION OF PSYCHOLOGICAL DISTRESS. LINEAR REGRESSION ANALYSIS SHOWED THAT YOGA SIGNIFICANTLY IMPROVES PSYCHOLOGICAL QUALITY OF LIFE (P=0.046). CONCLUSION: YOGA IN PRIMARY CARE IS FEASIBLE, SAFE AND HAS A SATISFACTORY ADHERENCE, AS WELL AS A POSITIVE EFFECT ON PSYCHOLOGICAL QUALITY OF LIFE OF PARTICIPANTS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
18  719  47 EFFECT OF IYENGAR YOGA ON MENTAL HEALTH OF INCARCERATED WOMEN: A FEASIBILITY STUDY. BACKGROUND: INCARCERATED WOMEN SHARE A DISPROPORTIONATE BURDEN OF MENTAL ILLNESS. ALTHOUGH PSYCHOTROPIC MEDICATIONS ARE AVAILABLE TO WOMEN IN PRISON, ADJUNCTIVE TREATMENT MODALITIES, SUCH AS IYENGAR YOGA, MAY INCREASE PSYCHOLOGICAL WELL-BEING. OBJECTIVES: THE PURPOSES OF THIS STUDY WERE (A) TO ADDRESS THE FEASIBILITY OF PROVIDING A GENDER-RESPONSIVE EXERCISE INTERVENTION WITHIN A CORRECTIONAL INSTITUTION AND (B) TO OBSERVE THE EFFECT OF A GROUP-FORMAT IYENGAR YOGA PROGRAM THAT MET TWO SESSIONS A WEEK FOR 12 WEEKS ON LEVELS OF DEPRESSION SYMPTOMS, ANXIETY SYMPTOMS, AND PERCEIVED STRESS AMONG INCARCERATED WOMEN. METHODS: A REPEATED MEASURES DESIGN, IN WHICH EACH PARTICIPANT SERVED AS HER OWN CONTROL, WAS USED. PARTICIPANTS COMPLETED THREE SELF-ADMINISTERED INSTRUMENTS: THE BECK DEPRESSION INVENTORY, THE BECK ANXIETY INVENTORY, AND THE PERCEIVED STRESS SCALE BEFORE TREATMENT (BASELINE) AND DURING TREATMENT (WEEKS 4, 8, AND 12). LINEAR MIXED EFFECTS MODELS WERE USED TO EXAMINE STATISTICALLY SIGNIFICANT CHANGES IN MENTAL HEALTH MEASURES OVER TIME, TAKING ADVANTAGE OF ALL AVAILABLE DATA. RESULTS: ALTHOUGH 21 WOMEN INITIALLY PARTICIPATED IN THE INTERVENTION, 6 WOMEN COMPLETED THE 12-WEEK INTERVENTION. A SIGNIFICANT LINEAR DECREASE WAS DEMONSTRATED IN SYMPTOMS OF DEPRESSION OVER TIME, WITH MEAN VALUES CHANGING FROM 24.90 AT BASELINE TO 5.67 AT WEEK 12. THERE WAS A MARGINALLY SIGNIFICANT DECREASE IN ANXIETY OVER TIME (12.00 AT BASELINE TO 7.33 AT WEEK 12) AND A NONLINEAR CHANGE IN STRESS OVER TIME, WITH DECREASES FROM BASELINE TO WEEK 4 AND SUBSEQUENT INCREASES TO WEEK 12. DISCUSSION: WOMEN WHO PARTICIPATED IN THIS PROGRAM EXPERIENCED FEWER SYMPTOMS OF DEPRESSION AND ANXIETY OVER TIME. FINDINGS FROM THIS STUDY MAY BE USED TO IMPROVE FUTURE INTERVENTIONS FOCUSING ON THE HEALTH OUTCOMES OF INCARCERATED WOMEN.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
19   70  39 A FEASIBILITY STUDY EXAMINING THE IMPACT OF YOGA ON PSYCHOSOCIAL HEALTH AND SYMPTOMS IN PEDIATRIC OUTPATIENTS RECEIVING CHEMOTHERAPY. PURPOSE: PEDIATRIC CANCER PATIENTS EXPERIENCE SYMPTOMS THAT NEGATIVELY IMPACT QUALITY OF LIFE; YOGA MAY BE AN EFFECTIVE INTERVENTION. THE PRIMARY OBJECTIVE WAS TO DETERMINE THE FEASIBILITY OF A 10-WEEK, WEEKLY INDIVIDUALIZED YOGA INTERVENTION FOR CHILDREN AND ADOLESCENTS RECEIVING OUTPATIENT CANCER THERAPY PRIMARILY DELIVERED REMOTELY USING SKYPE. SECONDARY OBJECTIVES WERE TO DESCRIBE DEPRESSION, ANXIETY, ANGER, FATIGUE, QUALITY OF LIFE, AND SYMPTOMS AT 5 AND 10 WEEKS AFTER ENROLLMENT. METHODS: WE INCLUDED ENGLISH-SPEAKING PATIENTS AGED 10 TO 18 YEARS RECEIVING OUTPATIENT CHEMOTHERAPY FOR CANCER. WEEKLY INDIVIDUALIZED YOGA SESSIONS WERE OFFERED FOR 10 WEEKS. WEEKS 1, 5, AND 10 WERE IN-HOSPITAL WHILE THE REMAINING SESSIONS WERE DELIVERED REMOTELY USING SKYPE. TWICE WEEKLY, HOMEWORK WAS ASSIGNED BETWEEN EACH SESSION. THE PRIMARY OUTCOME WAS FEASIBILITY, DEFINED AS 80% OF PARTICIPANTS COMPLETING AT LEAST 60% OF PLANNED IN-HOSPITAL OR REMOTE YOGA SESSIONS. RESULTS: BETWEEN MARCH AND NOVEMBER 2017, 10 PATIENTS WERE ENROLLED. TWO PATIENTS DISCONTINUED THE STUDY AFTER ONE AND TWO SESSIONS. ONLY SIX PARTICIPANTS ACHIEVED AT LEAST 60% OF PLANNED YOGA SESSIONS AND THUS, THE STUDY DID NOT MEET THE A PRIORI DEFINED FEASIBILITY THRESHOLD. AMONG ALL PARTICIPANTS, ONLY ONE HOMEWORK SESSION WAS PERFORMED. CONCLUSIONS: A 10-WEEK INDIVIDUALIZED IN-PERSON AND REMOTELY CONDUCTED YOGA INTERVENTION WAS NOT FEASIBLE IN CHILDREN RECEIVING CANCER TREATMENTS BECAUSE OF FAILURE TO ACHIEVE THE DESIRED FREQUENCY OF YOGA SESSIONS IN A SUFFICIENT NUMBER OF PARTICIPANTS. FUTURE RESEARCH SHOULD IDENTIFY APPROACHES TO IMPROVE COMPLIANCE WITH REMOTE YOGA SESSIONS AND HOME PRACTICE. TRIAL REGISTRATION: NCT03318068.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
20  345  38 ASSESSING FEASIBILITY AND ACCEPTABILITY OF YOGA AND GROUP CBT FOR ADOLESCENTS WITH DEPRESSION: A PILOT RANDOMIZED CLINICAL TRIAL. PURPOSE: GIVEN INCREASING RATES OF DEPRESSION IN ADOLESCENTS, THERE IS A CLEAR NEED FOR INNOVATIVE TREATMENTS. IN THIS PILOT RANDOMIZED CLINICAL TRIAL, WE ASSESSED ACCEPTABILITY AND FEASIBILITY OF TWO GROUP-BASED INTERVENTIONS: YOGA AND COGNITIVE-BEHAVIORAL THERAPY (CBT). THE GOAL OF THIS WORK IS TO PREPARE FOR A FUTURE FULLY POWERED RANDOMIZED TRIAL TO TEST THE HYPOTHESIS THAT YOGA IS NOT INFERIOR TO AN ESTABLISHED ADOLESCENT DEPRESSION TREATMENT, NAMELY, GROUP CBT. METHODS: WE ENROLLED 42 ADOLESCENTS WITH ELEVATED DEPRESSION SYMPTOMS. PARTICIPANTS WERE RANDOMLY ASSIGNED TO A 12-WEEK GROUP-BASED INTERVENTION, YOGA OR CBT. WE HAD A PRIORI FEASIBILITY AND ACCEPTABILITY TARGETS, INCLUDING FOR RECRUITMENT RATE, RETENTION RATE, EXPECTANCY, CREDIBILITY, PROGRAM SATISFACTION, CLASS ATTENDANCE, ENGAGEMENT IN HOME PRACTICE, AND INSTRUCTOR/LEADER MANUAL ADHERENCE. WE ASSESSED ADVERSE EVENTS, AND WITHIN-SUBJECT CHANGES IN OUTCOMES (DEPRESSION, ANXIETY, IMPAIRMENT, SLEEP DISTURBANCE) AND POSSIBLE MEDIATORS (MINDFULNESS, SELF-COMPASSION). RESULTS: BOTH INTERVENTIONS MET MOST ACCEPTABILITY AND FEASIBILITY TARGETS. THE ONLY TARGET NOT MET RELATED TO LOW ENGAGEMENT IN HOME PRACTICE. PARTICIPANTS WITHIN EACH STUDY ARM SHOWED DECREASED DEPRESSION SYMPTOMS OVER TIME AND INCREASED SELF-COMPASSION. CONCLUSIONS: A YOGA INTERVENTION APPEARS TO BE ACCEPTABLE AND FEASIBLE TO ADOLESCENTS WITH DEPRESSION. HOWEVER, IT MAY BE CHALLENGING FOR THIS GROUP TO ENGAGE IN UNSTRUCTURED HOME PRACTICE.	2022