1 1156 158 ENSURING YOGA INTERVENTION FIDELITY IN A RANDOMIZED PREFERENCE TRIAL FOR THE TREATMENT OF WORRY IN OLDER ADULTS. INTRODUCTION: YOGA FOR TREATMENT OF WORRY IN OLDER ADULTS IS AN INTERVENTION THAT IS ESPECIALLY LIKELY TO TRANSLATE INTO REAL-WORLD PRACTICE. ASSESSING TREATMENT FIDELITY IMPROVES CONFIDENCE THAT EFFECTIVE INTERVENTIONS CAN BE CONSISTENTLY APPLIED AND ALLOWS RESEARCHERS TO EXPLORE IF ANY NULL RESULTS FOR EFFECTIVENESS ARE INDEED THE RESULT OF A LACK OF INTERVENTION EFFICACY OR LACK OF PROPER INTERVENTION IMPLEMENTATION. METHODS: THIS STUDY DESCRIBES TREATMENT FIDELITY OF A YOGA INTERVENTION IN A RANDOMIZED PREFERENCE TRIAL THAT COMPARED COGNITIVE-BEHAVIORAL THERAPY (CBT) AND YOGA FOR THE TREATMENT OF WORRY, ANXIETY, AND SLEEP IN WORRIED OLDER (>/=60 YEARS) ADULTS. ESTABLISHED METHODS FOR ASSESSING TREATMENT FIDELITY OF CBT GUIDED THE PROCEDURE FOR ENSURING THAT THE YOGA INTERVENTION WAS DELIVERED AS INTENDED. THE YOGA INTERVENTION CONSISTED OF 20, 75-MIN, IN-PERSON, GROUP, GENTLE YOGA CLASSES HELD TWICE WEEKLY. RESULTS: SIX FEMALE INSTRUCTORS (MEAN AGE = 64 YEARS) TAUGHT 660 YOGA CLASSES THAT WERE VIDEOTAPED. TEN PERCENT OF THESE CLASSES, STRATIFIED BY INSTRUCTOR, WERE RANDOMLY SELECTED FOR REVIEW. THE AVERAGE ADHERENCE SCORE FOR YOGA INSTRUCTORS WAS 6.84 (RANGE 4-8). THE AVERAGE COMPETENCY SCORES WERE CONSISTENTLY HIGH, WITH AN AVERAGE SCORE OF 7.24 (RANGE 6-8). TEACHING CONTENT NOT INCLUDED IN THE PROTOCOL OCCURRED IN 26 (38.1%) SESSIONS AND DECREASED OVER TIME. OBSERVED RATINGS OF INSTRUCTOR ADHERENCE WERE SIGNIFICANTLY RELATED TO RATINGS OF COMPETENCY. INSTRUCTOR ADHERENCE WAS ALSO SIGNIFICANTLY ASSOCIATED WITH LOWER PARTICIPANT ATTENDANCE, BUT NOT WITH ANY OF THE OTHER PROCESS OR OUTCOME MEASURES. CONCLUSIONS: THE LARGER RANGE FOUND IN ADHERENCE RELATIVE TO COMPETENCE SCORES DEMONSTRATED THAT TEACHING A YOGA CLASS ACCORDING TO A PROTOCOL REQUIRES DIFFERENT SKILLS THAN COMPETENTLY TEACHING A YOGA CLASS IN THE COMMUNITY, AND THESE SKILLS IMPROVED WITH FEEDBACK. THESE RESULTS MAY FOSTER DIALOG BETWEEN THE YOGA RESEARCH AND PRACTICE COMMUNITIES. CLINICAL TRIAL REGISTRATION NO.: NCT02968238.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
2  345  46 ASSESSING FEASIBILITY AND ACCEPTABILITY OF YOGA AND GROUP CBT FOR ADOLESCENTS WITH DEPRESSION: A PILOT RANDOMIZED CLINICAL TRIAL. PURPOSE: GIVEN INCREASING RATES OF DEPRESSION IN ADOLESCENTS, THERE IS A CLEAR NEED FOR INNOVATIVE TREATMENTS. IN THIS PILOT RANDOMIZED CLINICAL TRIAL, WE ASSESSED ACCEPTABILITY AND FEASIBILITY OF TWO GROUP-BASED INTERVENTIONS: YOGA AND COGNITIVE-BEHAVIORAL THERAPY (CBT). THE GOAL OF THIS WORK IS TO PREPARE FOR A FUTURE FULLY POWERED RANDOMIZED TRIAL TO TEST THE HYPOTHESIS THAT YOGA IS NOT INFERIOR TO AN ESTABLISHED ADOLESCENT DEPRESSION TREATMENT, NAMELY, GROUP CBT. METHODS: WE ENROLLED 42 ADOLESCENTS WITH ELEVATED DEPRESSION SYMPTOMS. PARTICIPANTS WERE RANDOMLY ASSIGNED TO A 12-WEEK GROUP-BASED INTERVENTION, YOGA OR CBT. WE HAD A PRIORI FEASIBILITY AND ACCEPTABILITY TARGETS, INCLUDING FOR RECRUITMENT RATE, RETENTION RATE, EXPECTANCY, CREDIBILITY, PROGRAM SATISFACTION, CLASS ATTENDANCE, ENGAGEMENT IN HOME PRACTICE, AND INSTRUCTOR/LEADER MANUAL ADHERENCE. WE ASSESSED ADVERSE EVENTS, AND WITHIN-SUBJECT CHANGES IN OUTCOMES (DEPRESSION, ANXIETY, IMPAIRMENT, SLEEP DISTURBANCE) AND POSSIBLE MEDIATORS (MINDFULNESS, SELF-COMPASSION). RESULTS: BOTH INTERVENTIONS MET MOST ACCEPTABILITY AND FEASIBILITY TARGETS. THE ONLY TARGET NOT MET RELATED TO LOW ENGAGEMENT IN HOME PRACTICE. PARTICIPANTS WITHIN EACH STUDY ARM SHOWED DECREASED DEPRESSION SYMPTOMS OVER TIME AND INCREASED SELF-COMPASSION. CONCLUSIONS: A YOGA INTERVENTION APPEARS TO BE ACCEPTABLE AND FEASIBLE TO ADOLESCENTS WITH DEPRESSION. HOWEVER, IT MAY BE CHALLENGING FOR THIS GROUP TO ENGAGE IN UNSTRUCTURED HOME PRACTICE.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
3 1243  49 FEASIBILITY OF A YOGA, AEROBIC AND STRETCHING-TONING EXERCISE PROGRAM FOR ADULT CANCER SURVIVORS: THE STAYFIT TRIAL. BACKGROUND: THE USE OF YOGA AS A MIND-BODY PRACTICE HAS BECOME INCREASINGLY POPULAR AMONG CLINICAL POPULATIONS AND OLDER ADULTS WHO USE THIS PRACTICE TO MANAGE AGE AND CHRONIC DISEASE-RELATED SYMPTOMS. ALTHOUGH YOGA CONTINUES TO GAIN POPULARITY AMONG PRACTITIONERS AND RESEARCHERS, PILOT STUDIES THAT EXAMINE ITS FEASIBILITY AND ACCEPTABILITY, ESPECIALLY AMONG CANCER SURVIVORS, ARE LIMITED. FEASIBILITY STUDIES PLAY A CRITICAL ROLE IN DETERMINING WHETHER THE TARGET POPULATION IS LIKELY TO ENGAGE WITH LARGER SCALE EFFICACY AND EFFECTIVENESS TRIALS. IN THIS PAPER WE PRESENT FEASIBILITY AND ACCEPTABILITY DATA FROM A 12-WEEK RANDOMIZED CONTROLLED TRIAL (RCT) CONDUCTED WITH ADULT CANCER SURVIVORS. METHODS: PARTICIPANTS N = 78 (MEAN AGE: 55 YEARS) WERE RANDOMIZED TO ONE OF THREE GROUPS: A HATHA YOGA, AEROBIC EXERCISE, OR STRETCHING-TONING CONTROL GROUP WITH GROUP EXERCISE CLASSES HELD FOR 150 MIN/WEEK FOR 12 WEEKS. HEREIN WE REPORT FEASIBILITY AND ACCEPTABILITY, INCLUDING ENROLLMENT RATES, ATTENDANCE, ATTRITION AND ADVERSE EVENTS, AND PARTICIPANT FEEDBACK AND SATISFACTION DATA. RESULTS: OF THE 233 ADULTS SCREENED, 109 WERE ELIGIBLE AND 78 RANDOMIZED TO ONE OF THE THREE INTERVENTION ARMS. SESSION ATTENDANCE WAS HIGH FOR ALL GROUPS (75.5-89.5%) AND 17 PARTICIPANTS DROPPED OUT DURING THE 12-WEEK INTERVENTION. PROGRAM SATISFACTION WAS HIGH (4.8 OR HIGHER OUT OF 5) AND NO ADVERSE EVENTS WERE REPORTED. ONE COHORT (N = 15) OF THE INTERVENTION TRANSITIONED TO REMOTE INTERVENTION DELIVERY DUE TO THE COVID-19 PANDEMIC. FEASIBILITY DATA FROM THESE PARTICIPANTS SUGGESTED THAT SYNCHRONIZED GROUP EXERCISE CLASSES VIA ZOOM WITH A LIVE INSTRUCTOR WERE ACCEPTABLE AND ENJOYABLE. PARTICIPANT FEEDBACK REGARDING MOST AND LEAST HELPFUL ASPECTS OF THE PROGRAM AS WELL AS SUGGESTIONS FOR FUTURE YOGA INTERVENTIONS ARE SUMMARIZED. CONCLUSIONS: OVERALL, THE YOGA INTERVENTION WAS HIGHLY FEASIBLE AND ACCEPTABLE. THE FEASIBILITY PARAMETERS FROM THIS TRIAL CAN AID RESEARCHERS IN ESTIMATING RECRUITMENT RATES FOR DESIRED SAMPLE SIZES TO SUCCESSFULLY RANDOMIZE AND RETAIN CANCER SURVIVORS IN SHORT- AND LONG-TERM YOGA-BASED EFFICACY AND EFFECTIVENESS TRIALS. THE FINDINGS ALSO PROVIDE EVIDENCE TO CLINICIANS WHO CAN RECOMMEND UP TO 150 MIN OF A COMBINATION OF EXERCISES-AEROBIC, YOGA, OR STRETCHING-TONING TO THEIR CANCER PATIENTS IN ORDER TO IMPROVE HEALTH AND WELLBEING DURING CANCER SURVIVORSHIP.	2021	
                                                                                                                                                                                                                                                                 
4 1242  46 FEASIBILITY OF A YOGA INTERVENTION TO DECREASE PAIN IN OLDER WOMEN: A RANDOMIZED CONTROLLED PILOT STUDY. BACKGROUND: A SIGNIFICANT PROPORTION OF OLDER WOMEN SUFFER FROM CHRONIC PAIN, WHICH CAN DECREASE QUALITY OF LIFE. THE OBJECTIVE OF THIS PILOT RANDOMIZED STUDY WAS TO EVALUATE THE FEASIBILITY OF A FLOW-RESTORATIVE YOGA INTERVENTION DESIGNED TO DECREASE PAIN AND RELATED OUTCOMES AMONG WOMEN AGED 60 OR OLDER. METHODS: FLOW-RESTORATIVE YOGA CLASSES WERE HELD TWICE WEEKLY FOR 1 HOUR AND LED BY A CERTIFIED YOGA INSTRUCTOR. PARTICIPANTS RANDOMIZED TO THE INTERVENTION GROUP ATTENDED THE YOGA CLASSES FOR 12 WEEKS AND RECEIVED SUPPLEMENTAL MATERIALS FOR AT-HOME PRACTICE. THOSE RANDOMIZED TO THE CONTROL GROUP WERE ASKED TO MAINTAIN THEIR NORMAL DAILY ROUTINE. FEASIBILITY WAS EVALUATED USING RECRUITMENT AND RETENTION RATES, CLASS AND HOME PRACTICE ADHERENCE RATES, AND PARTICIPANT SATISFACTION SURVEYS. OUTCOME MEASURES (SELF-REPORTED PAIN, INFLAMMATORY MARKERS, FUNCTIONAL FITNESS, QUALITY OF LIFE, RESILIENCE, AND SELF-REPORTED PHYSICAL ACTIVITY) WERE ASSESSED AT BASELINE AND POST-INTERVENTION. PAIRED T-TESTS OR WILCOXON SIGNED-RANK TESTS WERE USED TO EXAMINE CHANGES IN OUTCOME MEASURES WITHIN TREATMENT GROUPS. RESULTS: THIRTY-EIGHT PARTICIPANTS WERE RECRUITED AND RANDOMIZED. PARTICIPANTS WERE PRIMARILY WHITE, COLLEGE-EDUCATED, AND HIGHER FUNCTIONING, DESPITE EXPERIENCING VARIOUS FORMS OF CHRONIC PAIN. ATTENDANCE AND RETENTION RATES WERE HIGH (91 AND 97%, RESPECTIVELY) AND THE MAJORITY OF PARTICIPANTS WERE SATISFIED WITH THE YOGA PROGRAM (89%) AND WOULD RECOMMEND IT TO OTHERS (87%). INTERVENTION PARTICIPANTS ALSO EXPERIENCED REDUCTIONS IN PAIN INTERFERENCE AND IMPROVEMENTS IN ENERGY AND SOCIAL FUNCTIONING. CONCLUSIONS: THIS PILOT STUDY PROVIDES ESSENTIAL DATA TO INFORM A FULL SCALE RANDOMIZED TRIAL OF FLOW-RESTORATIVE YOGA FOR OLDER WOMEN WITH CHRONIC PAIN. FUTURE STUDIES SHOULD EMPHASIZE STRATEGIES TO RECRUIT A MORE DIVERSE STUDY POPULATION, PARTICULARLY OLDER WOMEN AT HIGHER RISK OF DISABILITY AND FUNCTIONAL DECLINE. TRIAL REGISTRATION: CLINICALTRIALS.GOV , NCT03790098 . REGISTERED 31 DECEMBER 2018 - RETROSPECTIVELY REGISTERED.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
5 1684  33 OPEN TRIAL OF VINYASA YOGA FOR PERSISTENTLY DEPRESSED INDIVIDUALS: EVIDENCE OF FEASIBILITY AND ACCEPTABILITY. THE AIM OF THIS STUDY WAS TO ASSESS THE ACCEPTABILITY AND FEASIBILITY OF VINYASA YOGA AS AN ADJUNCTIVE TREATMENT FOR DEPRESSED PATIENTS WHO WERE NOT RESPONDING ADEQUATELY TO ANTIDEPRESSANT MEDICATION. THE AUTHORS ALSO PLANNED TO ASK PARTICIPANTS FOR QUALITATIVE FEEDBACK ON THEIR EXPERIENCE OF THE CLASS AND TO ASSESS CHANGE OVER TIME IN DEPRESSION AND IN POSSIBLE MEDIATING VARIABLES. THE AUTHORS RECRUITED 11 PARTICIPANTS IN 1 MONTH FOR AN 8-WEEK OPEN TRIAL OF YOGA CLASSES. THEY FOUND THAT 10 PARTICIPANTS COMPLETED FOLLOW-UP ASSESSMENTS, 9 OF 10 WERE POSITIVE ABOUT THEIR EXPERIENCE, AND ALL PROVIDED FEEDBACK ABOUT WHAT WAS AND WAS NOT HELPFUL ABOUT YOGA, AS WELL AS BARRIERS TO CLASS ATTENDANCE. OVER THE 2-MONTH PERIOD, PARTICIPANTS EXHIBITED SIGNIFICANT DECREASES IN DEPRESSION SYMPTOMS AND SIGNIFICANT INCREASES IN AN ASPECT OF MINDFULNESS AND IN BEHAVIOR ACTIVATION. THIS PILOT STUDY PROVIDED SUPPORT FOR CONTINUING TO INVESTIGATE VINYASA YOGA AS AN ADJUNCT TREATMENT FOR DEPRESSION. THE NEXT STEP REQUIRED IS A RIGOROUS RANDOMIZED CLINICAL TRIAL.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
6 1997  57 STRATEGIES FOR EVALUATING SELF-EFFICACY AND OBSERVED SUCCESS IN THE PRACTICE OF YOGA POSTURES FOR THERAPEUTIC INDICATIONS: METHODS FROM A YOGA INTERVENTION FOR URINARY INCONTINENCE AMONG MIDDLE-AGED AND OLDER WOMEN. BACKGROUND: MOST CLINICAL INVESTIGATIONS INVOLVING YOGA LACK ADEQUATE DESCRIPTION OF THE SPECIFIC YOGA ELEMENTS, INCLUDING PHYSICAL POSTURES. FEW STUDIES HAVE MEASURED SELF-EFFICACY REGARDING THE PERFORMANCE OF YOGA POSTURES OR ASSESSED OBSERVED SUCCESS IN PERFORMING POSTURES. METHODS: WE DEVELOPED AND PILOTED SEVERAL TOOLS TO EVALUATE SELF-EFFICACY AND OBSERVED SUCCESS IN PRACTICING YOGA IN THE CONTEXT OF A RANDOMIZED FEASIBILITY TRIAL OF AN IYENGAR-BASED YOGA INTERVENTION FOR URINARY INCONTINENCE IN AMBULATORY WOMEN >/=50 YEARS. AT THE END OF THE 12-WEEK YOGA INTERVENTION INVOLVING TWICE WEEKLY GROUP YOGA CLASSES AND ONCE WEEKLY HOME PRACTICE, PARTICIPANTS RATED THEIR SELF-EFFICACY IN PERFORMING EACH OF THE INCLUDED 15 YOGA POSTURES ON A 5-POINT LIKERT SCALE. DURING THE 12TH WEEK, AN EXPERT YOGA CONSULTANT OBSERVED PARTICIPANTS AND RATED THEIR COMPETENCY IN PERFORMING POSTURES ON A 5-POINT SCALE. PARTICIPANTS COMPLETED A QUESTIONNAIRE ABOUT SELF-EFFICACY IN ADHERING TO HOME YOGA PRACTICE. WE EXAMINED THE DISTRIBUTION OF AND CORRELATIONS BETWEEN SCORES ON THE ABOVE MEASURES. RESULTS: AMONG 27 PARTICIPANTS (MEAN AGE 65 YEARS), THE RANGE OF MEANS FOR SELF-EFFICACY RATINGS FOR INDIVIDUAL POSTURES WAS 3.6 TO 4.5. THE RANGE OF MEANS FOR OBSERVED COMPETENCY RATINGS FOR INDIVIDUAL POSTURES WAS 3.3 TO 5.0. MEAN SELF-EFFICACY RATING FOR CONFIDENCE IN ADHERING TO THE ASSIGNED ONCE-WEEKLY HOME YOGA PRACTICE WAS 2.8 (RANGE 1 TO 5). POSTURE SELF-EFFICACY WAS INVERSELY CORRELATED WITH PARTICIPANT AGE (P = 0.01) AND POSITIVELY CORRELATED WITH SELF-REPORTED PHYSICAL FUNCTION (P = 0.03) AND MOBILITY (P = 0.01). NO SIGNIFICANT CORRELATIONS WERE FOUND BETWEEN POSTURE SELF-EFFICACY SCALE SCORES AND EXPERT-OBSERVED YOGA COMPETENCY RATINGS OR PRACTICE ADHERENCE SELF-EFFICACY SCORES. CONCLUSIONS: THESE MEASURES HOLD PROMISE FOR ADVANCING YOGA RESEARCH AND PRACTICE BY DESCRIBING METHODS TO: 1) MEASURE SELF-EFFICACY IN PERFORMING SPECIFIC YOGA POSTURES; 2) USE AN EXPERT OBSERVER TO ASSESS PARTICIPANTS' COMPETENCE IN PERFORMING YOGA POSTURES; AND 3) MEASURE SELF-EFFICACY IN ADHERING TO HOME PRACTICE. THESE PROPOSED MEASURES CAN BE USED TO DESCRIBE SPECIFIC COMPONENTS OF YOGA INTERVENTIONS, TO ASSESS WHETHER STUDY PARTICIPANTS ARE ABLE TO LEARN TO PRACTICE PHYSICAL ASPECTS OF YOGA AND/OR MAINTAIN THIS PRACTICE OVER TIME, AS WELL AS TO INVESTIGATE RELATIONSHIPS BETWEEN SELF-EFFICACY AND COMPETENCY IN PERFORMING YOGA POSTURES TO ACHIEVE SPECIFIC HEALTH OUTCOMES. TRIAL REGISTRATION: CLINICALTRIALS.GOV, NCT02342678, JANUARY 21, 2015.	2020	

7  112  40 A PILOT STUDY OF A MINDFULNESS INFORMED YOGA INTERVENTION IN YOUNG PEOPLE WITH PSYCHOSIS. AIM: TO DETERMINE THE ACCEPTABILITY AND SAFETY OF A MINDFULNESS INFORMED YOGA INTERVENTION AS ADJUNCT TO USUAL CARE FOR YOUNG PEOPLE WITH EARLY PSYCHOSIS. METHODS: PEOPLE AGED 16-25 YEARS ATTENDING A COMMUNITY-BASED SPECIALIST EARLY PSYCHOSIS CLINIC WERE INVITED TO PARTICIPATE IN A 12-WEEK YOGA INTERVENTION. THE INTERVENTION CONSISTED OF 1-H WEEKLY CLASSES OF MINDFULNESS INFORMED YOGA. ACCEPTABILITY WAS MEASURED BY UPTAKE, ATTENDANCE AND PARTICIPANTS' SATISFACTION. SAFETY WAS MEASURED BY INCIDENCE OF PHYSICAL INJURY, PARTICIPANTS' LEVEL OF COMFORT, DISTRESS AND ANXIETY DURING THE SESSIONS, AND THE FOLLOWING MENTAL HEALTH OUTCOMES: POSITIVE AND NEGATIVE PSYCHOTIC, DEPRESSION, ANXIETY AND STRESS SYMPTOMS, SLEEP QUALITY AND FUNCTIONING. RESULTS: OF THOSE WHO CONSENTED TO THE STUDY, 80% (12) PARTICIPATED AND ON AVERAGE ATTENDED 4.4 YOGA CLASSES. THERE WERE NO PHYSICAL INJURIES AND PARTICIPANTS REPORTED MINIMAL DISTRESS AND ANXIETY. POST-INTERVENTION, THERE WAS A SIGNIFICANT REDUCTION IN ANXIETY SYMPTOMS AND AN IMPROVEMENT IN FUNCTION. CONCLUSIONS: MINDFULNESS-BASED YOGA INTERVENTIONS ARE BOTH ACCEPTABLE AND SAFE AS AN INTERVENTION FOR YOUTH WITH EARLY PSYCHOSIS. THOUGH NUMBERS WERE SMALL, THE STUDY SHOWS PROMISE FOR YOGA AS A POTENTIALLY USEFUL INTERVENTION. IMPORTANTLY, THERE WAS NO DETERIORATION IN MENTAL HEALTH OUTCOMES. A LARGER TRIAL EVALUATING CLINICAL EFFECTIVENESS IS NOW TIMELY.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
8  115  36 A PILOT STUDY OF A YOGA INTERVENTION FOR THE TREATMENT OF ANXIETY IN YOUNG PEOPLE WITH EARLY PSYCHOSIS. BACKGROUND: ANXIETY IS COMMON IN YOUNG PEOPLE WITH EARLY PSYCHOSIS AND TREATMENT OPTIONS FOR THIS CO-MORBIDITY REMAIN LIMITED. YOGA IS A PROMISING ADJUNCT INTERVENTION THAT HAS BEEN SHOWN TO REDUCE ANXIETY FOR ADULTS WITH SCHIZOPHRENIA, THEREFORE THIS PILOT STUDY EVALUATED THE ACCEPTABILITY AND POTENTIAL EFFECTIVENESS OF YOGA FOR ANXIETY IN EARLY PSYCHOSIS. METHODS: A PROSPECTIVE SINGLE ARM PILOT STUDY OF A YOGA INTERVENTION WAS CONDUCTED WITHIN AN EARLY INTERVENTION FOR PSYCHOSIS SERVICE. RATES OF ATTENDANCE, AS WELL AS SYMPTOMS OF ANXIETY PRE AND POST YOGA SESSION WERE MEASURED. RESULTS: A TOTAL OF 14 YOUNG PEOPLE PARTICIPATED IN THE STUDY AND OVER 70% ATTENDED HALF OR MORE OF THE YOGA SESSIONS OFFERED. SIGNIFICANT TRANSIENT REDUCTION IN STATE ANXIETY AFTER A SINGLE SESSION OF YOGA WAS OBSERVED (P < 0.01). CONCLUSIONS: YOGA WAS FOUND TO BE AN ACCEPTABLE AND POTENTIALLY EFFECTIVE ADJUNCTIVE TREATMENT FOR ANXIETY IN EARLY PSYCHOSIS AND THE RESULTS WARRANT FURTHER CLINICAL TRIALS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
9 2385  33 YOGA ADHERENCE IN OLDER WOMEN SIX MONTHS POST-OSTEOARTHRITIS INTERVENTION. BACKGROUND/OBJECTIVE: OSTEOARTHRITIS (OA) IS A HIGHLY PREVALENT CONDITION WORLDWIDE. YOGA IS POTENTIALLY A SAFE AND FEASIBLE OPTION FOR MANAGING OA; HOWEVER, THE EXTENT OF LONG-TERM YOGA ADHERENCE IS UNKNOWN. THE PURPOSE OF THIS STUDY WAS TO EXAMINE YOGA ADHERENCE 6 MONTHS AFTER PARTICIPANTS COMPLETED AN OA INTERVENTION PROGRAM. METHODS: THIS FOLLOW-UP STUDY EMPLOYED A CROSS-SECTIONAL DESCRIPTIVE DESIGN USING SURVEY, INTERVIEW, AND VIDEO RECORDINGS TO COLLECT BOTH QUANTITATIVE AND QUALITATIVE DATA. A TOTAL OF 31 PARTICIPANTS COMPLETED AND RETURNED THE SURVEY, AND 10 VIDEOTAPED THEIR YOGA PRACTICE FOR 1 WEEK AND PARTICIPATED IN A FACE-TO-FACE INTERVIEW. RESULTS: A MAJORITY OF PARTICIPANTS (N=19, 61%) REPORTED THAT THEY WERE STILL PRACTICING YOGA 6 MONTHS AFTER THE INTERVENTION PROGRAM. ON AVERAGE, PARTICIPANTS REPORTED PRACTICING 21 TO 30 MINUTES OF YOGA PER DAY (32%) 3 TO 4 DAYS PER WEEK (47%). "FEELING GOOD OR FEELING BETTER AFTER YOGA PRACTICE" (50%) AND "SET ASIDE A TIME" (31%) WERE THE MOST COMMON MOTIVATING FACTORS FOR YOGA ADHERENCE. DEALING WITH HEALTH PROBLEMS (42%), HAVING PAIN (25%), AND BEING TOO BUSY (25%) WERE THE MAJOR BARRIERS. QUALITATIVE DATA REVEALED THAT PARTICIPANTS: (1) USED MINDFUL YOGA MOVEMENT, (2) INCORPORATED OTHER FORMS OF EXERCISE AND RESOURCES DURING YOGA PRACTICE, AND (3) CREATED PERSONALIZED YOGA PROGRAMS. ADDITIONALLY, THE PARTICIPANTS REPORTED LESS OA PAIN, INCREASED PHYSICAL ENDURANCE, AND MORE RELAXATION. CONCLUSION: MANY PARTICIPANTS ADHERED TO YOGA PRACTICE 6 MONTHS POST-INTERVENTION ALTHOUGH NOT AT THE FREQUENCY AND SEQUENCE AS PRESCRIBED. FEELING BETTER AFTER PRACTICE MOTIVATED PARTICIPANTS, BUT OTHER FACTORS REMAINED KEY BARRIERS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
10 2837  41 YOGA'S IMPACT ON RISK AND PROTECTIVE FACTORS FOR DISORDERED EATING: A PILOT PREVENTION TRIAL. YOGA HAS BEEN PROPOSED AS A STRATEGY FOR IMPROVING RISK AND PROTECTIVE FACTORS FOR EATING DISORDERS, BUT FEW PREVENTION TRIALS HAVE BEEN CONDUCTED. THE PURPOSE OF THIS PILOT STUDY WAS TO ASSESS THE FEASIBILITY AND ACCEPTABILITY OF A YOGA SERIES IN FEMALE COLLEGE STUDENTS (N = 52). PARTICIPANTS WERE RANDOMIZED TO A YOGA INTERVENTION (THREE 50-MINUTE YOGA CLASSES/WEEK FOR 10 WEEKS CONDUCTED BY CERTIFIED YOGA TEACHERS WHO RECEIVED A 3-DAY INTENSIVE TRAINING) OR A CONTROL GROUP. RISK AND PROTECTIVE FACTORS, ASSESSED AT BASELINE, 5 AND 10 WEEKS, INCLUDED BODY DISSATISFACTION, NEGATIVE AFFECT, LONELINESS, SELF-COMPASSION, POSITIVE AFFECT, AND MINDFULNESS. MIXED MODELS CONTROLLING FOR BASELINE LEVELS OF OUTCOME VARIABLES WERE RUN. ON AVERAGE, PARTICIPANTS ATTENDED 20 OUT OF 30 YOGA CLASSES, AND THE MAJORITY OF PARTICIPANTS REPORTED HIGH LEVELS OF SATISFACTION WITH THE YOGA SERIES. APPEARANCE ORIENTATION DECREASED AND POSITIVE AFFECT INCREASED IN THE YOGA GROUP RELATIVE TO THE CONTROL GROUP. AFTER CONTROLLING FOR BASELINE LEVELS, THE YOGA GROUP HAD A SIGNIFICANTLY HIGHER POSITIVE AFFECT THAN THE CONTROL GROUP. CHANGES IN OTHER OUTCOMES WERE NOT STATISTICALLY SIGNIFICANT, AS COMPARED TO THE CONTROL CONDITION. FUTURE YOGA RESEARCH DIRECTIONS ARE DISCUSSED INCLUDING EDUCATION ABOUT BODY IMAGE, MEASURE AND SAMPLE SELECTION, AND USE OF AN IMPLEMENTATION SCIENCE FRAMEWORK.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
11  188  51 A RANDOMIZED PREFERENCE TRIAL OF COGNITIVE-BEHAVIORAL THERAPY AND YOGA FOR THE TREATMENT OF WORRY IN ANXIOUS OLDER ADULTS. BACKGROUND: WORRY IS A COMMON PROBLEM AMONG OLDER ADULTS. COGNITIVE-BEHAVIORAL THERAPY IS THE MOST STUDIED NONPHARMACOLOGICAL INTERVENTION AND IT HAS DEMONSTRATED EFFICACY IN REDUCING LATE-LIFE WORRY AND ANXIETY. ALTHOUGH THE EVIDENCE-BASE IS SMALLER, YOGA HAS BEEN SHOWN TO REDUCE ANXIETY AND STRESS. HOWEVER, LITTLE IS KNOWN ABOUT THE RELATIVE EFFECTIVENESS OF THESE TWO NONPHARMACOLOGICAL INTERVENTIONS. FURTHER, THE IMPACT OF PATIENT PREFERENCE ON OUTCOMES IS UNKNOWN.PURPOSE: THE PURPOSE TO THIS STUDY IS TO COMPARE THE EFFECTIVENESS OF COGNITIVE-BEHAVIORAL THERAPY (CBT) WITH YOGA FOR IMPROVING LATE-LIFE WORRY, ANXIETY, AND SLEEP. WE WILL ALSO EXAMINE THE EFFECTS OF PREFERENCE AND SELECTION ON OUTCOMES, ADHERENCE, AND ATTRITION. METHODS: WE ARE CONDUCTING A TWO-STAGE RANDOMIZED PREFERENCE TRIAL COMPARING CBT AND YOGA FOR THE REDUCTION OF WORRY IN A SAMPLE OF ANXIOUS OLDER ADULTS. FIVE HUNDRED PARTICIPANTS WILL BE RANDOMIZED TO EITHER THE PREFERENCE TRIAL (PARTICIPANTS CHOOSE THE INTERVENTION; N=250) OR TO THE RANDOMIZED TRIAL (PARTICIPANTS ARE RANDOMIZED TO ONE OF THE TWO INTERVENTIONS; N=250) WITH EQUAL PROBABILITY. CBT CONSISTS OF 10 TELEPHONE-BASED SESSIONS WITH AN ACCOMPANYING WORKBOOK. YOGA CONSISTS OF 10 WEEKS OF GROUP YOGA CLASSES (TWICE A WEEK) THAT IS MODIFIED FOR USE WITH OLDER ADULTS. CONCLUSIONS: THE STUDY DESIGN IS BASED ON FEEDBACK FROM ANXIOUS OLDER ADULTS WHO WANTED MORE NONPHARMACOLOGICAL OPTIONS FOR INTERVENTION AS WELL AS MORE INPUT INTO THE INTERVENTION THEY RECEIVE. IT IS THE FIRST HEAD-TO-HEAD COMPARISON OF CBT AND YOGA FOR REDUCING LATE-LIFE WORRY AND ANXIETY. IT WILL ALSO PROVIDE INFORMATION ABOUT HOW INTERVENTION PREFERENCE AFFECTS OUTCOMES. TRIAL REGISTRATION: CLINICALTRIALS.GOV NCT02968238.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
12 2367  31 WEEKLY ASSESSMENT OF NUMBER OF YOGA CLASSES AND AMOUNT OF YOGA HOME PRACTICE: AGREEMENT WITH DAILY DIARIES. OBJECTIVE: TO EVALUATE A WEEKLY YOGA PRACTICE ASSESSMENT INSTRUMENT DESIGNED TO ASSESS NUMBER OF CLASSES ATTENDED IN THE PREVIOUS WEEK, NUMBER OF TIMES ENGAGED IN FORMAL HOME YOGA PRACTICE, TOTAL NUMBER OF MINUTES ENGAGED IN FORMAL HOME YOGA PRACTICE IN THE PAST WEEK, AND NUMBER OF TIMES ENGAGED IN INFORMAL HOME YOGA PRACTICE. "INFORMAL" PRACTICE WAS DEFINED AS "IN THE MIDDLE OF OTHER ACTIVITIES, YOU SPENT A FEW MOMENTS ENGAGED IN ASANAS/POSTURES, FOCUS ON BREATH, BODY AWARENESS, OR VERY BRIEF MEDITATION, FOR LESS THAN 5 MIN AT A TIME." WE ASSESSED AGREEMENT BETWEEN THIS WEEKLY ASSESSMENT AND A DAILY HOME PRACTICE LOG. DESIGN AND SETTING: SEVENTY-TWO COMMUNITY YOGA PRACTITIONERS COMPLETED ONLINE DAILY YOGA LOGS FOR 28 DAYS AS WELL AS THE WEEKLY YOGA PRACTICE ASSESSMENT FOUR TIMES OVER THE 28 DAY PERIOD. RESULTS: WE EXAMINED AGREEMENT BETWEEN THE TWO METHODS ON THE FOUR INDICES OF AMOUNT OF WEEKLY YOGA PRACTICE. WE FOUND ACCEPTABLE AGREEMENT BETWEEN THE TWO METHODS FOR NUMBER OF CLASSES, NUMBER OF TIMES ENGAGED IN FORMAL HOME PRACTICE, AND TOTAL NUMBER OF MINUTES ENGAGED IN FORMAL HOME PRACTICE. AGREEMENT WAS LOWER FOR NUMBER OF TIMES ENGAGED IN INFORMAL PRACTICE. CONCLUSIONS: THESE DATA PROVIDE SUPPORT FOR USE OF A WEEKLY YOGA PRACTICE ASSESSMENT TO ASSESS NUMBER OF CLASSES ATTENDED AND AMOUNT OF FORMAL BUT NOT INFORMAL HOME PRACTICE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
13  445  30 CHAIR YOGA: FEASIBILITY AND SUSTAINABILITY STUDY WITH OLDER COMMUNITY-DWELLING ADULTS WITH OSTEOARTHRITIS. THIS STUDY MEASURED THE FEASIBILITY OF COMPLETING A RANDOMIZED CONTROL TRIAL ON AN 8-WEEK SEATED YOGA PROGRAM FOR OLDER ADULTS WITH OSTEOARTHRITIS. PART OF THE FEASIBILITY OF THIS PROGRAM WAS TO DETERMINE WHETHER PARTICIPANTS WOULD CONTINUE THE YOGA PRACTICE AT HOME USING A GUIDE BOOK AFTER THE 8-WEEK PROGRAM. FINDINGS DEMONSTRATED THAT ONCE PARTICIPANTS WERE NOT IN A GROUP SETTING FOR THE YOGA, THEY DID NOT CONTINUE WITH YOGA PRACTICE. THIS OUTCOME DEMONSTRATES THE NEED FOR GROUP PROGRAMS FOR OLDER ADULTS TO PROMOTE ADHERENCE TO MOVEMENT-BASED PROGRAMS. (TRIAL REGISTRATION: CLINICALTRIALS.GOV: NCT02113410).	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
14 1707  38 PATTERNS OF YOGA PRACTICE AND PHYSICAL ACTIVITY FOLLOWING A YOGA INTERVENTION FOR ADULTS WITH OR AT RISK FOR TYPE 2 DIABETES. BACKGROUND: THE CURRENT STUDY DESCRIBED PATTERNS OF YOGA PRACTICE AND EXAMINED DIFFERENCES IN PHYSICAL ACTIVITY OVER TIME BETWEEN INDIVIDUALS WITH OR AT RISK FOR TYPE 2 DIABETES WHO COMPLETED AN 8-WEEK YOGA INTERVENTION COMPARED WITH CONTROLS. METHODS: A LONGITUDINAL COMPARATIVE DESIGN MEASURED THE EFFECT OF A YOGA INTERVENTION ON YOGA PRACTICE AND PHYSICAL ACTIVITY, USING DATA AT BASELINE AND POSTINTERVENTION MONTHS 3, 6, AND 15. RESULTS: DISPARATE PATTERNS OF YOGA PRACTICE OCCURRED BETWEEN INTERVENTION AND CONTROL PARTICIPANTS OVER TIME, BUT THE SUBJECTIVE DEFINITION OF YOGA PRACTICE LIMITS INTERPRETATION. MULTILEVEL MODEL ESTIMATES INDICATED THAT TREATMENT GROUP DID NOT HAVE A SIGNIFICANT INFLUENCE IN THE RATE OF CHANGE IN PHYSICAL ACTIVITY OVER THE STUDY PERIOD. WHILE AGE AND EDUCATION WERE NOT SIGNIFICANT INDIVIDUAL PREDICTORS, THE INCLUSION OF THESE VARIABLES IN THE MODEL DID IMPROVE FIT. CONCLUSIONS: FINDINGS INDICATE THAT AN 8-WEEK YOGA INTERVENTION HAD LITTLE EFFECT ON PHYSICAL ACTIVITY OVER TIME. FURTHER RESEARCH IS NECESSARY TO EXPLORE THE INFLUENCE OF YOGA ON BEHAVIORAL HEALTH OUTCOMES AMONG INDIVIDUALS WITH OR AT RISK FOR TYPE 2 DIABETES.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
15  282  55 ADHERENCE TO YOGA AND EXERCISE INTERVENTIONS IN A 6-MONTH CLINICAL TRIAL. BACKGROUND: TO DETERMINE FACTORS THAT PREDICT ADHERENCE TO A MIND-BODY INTERVENTION IN A RANDOMIZED TRIAL. DESIGN: WE ANALYZED ADHERENCE DATA FROM A 3-ARM TRIAL INVOLVING 135 GENERALLY HEALTHY SENIORS 65-85 YEARS OF AGE RANDOMIZED TO A 6-MONTH INTERVENTION CONSISTING OF: AN IYENGAR YOGA CLASS WITH HOME PRACTICE, AN EXERCISE CLASS WITH HOME PRACTICE, OR A WAIT-LIST CONTROL GROUP. OUTCOME MEASURES INCLUDED COGNITIVE FUNCTION, MOOD, FATIGUE, ANXIETY, HEALTH-RELATED QUALITY OF LIFE, AND PHYSICAL MEASURES. ADHERENCE TO THE INTERVENTION WAS OBTAINED BY CLASS ATTENDANCE AND BIWEEKLY HOME PRACTICE LOGS. RESULTS: THE DROP-OUT RATE WAS 13%. AMONG THE COMPLETERS OF THE TWO ACTIVE INTERVENTIONS, AVERAGE YOGA CLASS ATTENDANCE WAS 77% AND HOME PRACTICE OCCURRED 64% OF ALL DAYS. AVERAGE EXERCISE CLASS ATTENDANCE WAS 69% AND HOME EXERCISE OCCURRED 54% OF ALL DAYS. THERE WERE NO CLEAR EFFECTS OF ADHERENCE ON THE SIGNIFICANT STUDY OUTCOMES (QUALITY OF LIFE AND PHYSICAL MEASURES). CLASS ATTENDANCE WAS SIGNIFICANTLY CORRELATED WITH BASELINE MEASURES OF DEPRESSION, FATIGUE, AND PHYSICAL COMPONENTS OF HEALTH-RELATED QUALITY OF LIFE. SIGNIFICANT DIFFERENCES IN BASELINE MEASURES WERE ALSO FOUND BETWEEN STUDY COMPLETERS AND DROP-OUTS IN THE ACTIVE INTERVENTIONS. ADHERENCE WAS NOT RELATED TO AGE, GENDER, OR EDUCATION LEVEL. CONCLUSION: HEALTHY SENIORS HAVE GOOD ATTENDANCE AT CLASSES WITH A PHYSICALLY ACTIVE INTERVENTION. HOME PRACTICE TAKES PLACE OVER HALF OF THE TIME. DECREASED ADHERENCE TO A POTENTIALLY BENEFICIAL INTERVENTION HAS THE POTENTIAL TO DECREASE THE EFFECT OF THE INTERVENTION IN A CLINICAL TRIAL BECAUSE SUBJECTS WHO MIGHT SUSTAIN THE GREATEST BENEFIT WILL RECEIVE A LOWER DOSE OF THE INTERVENTION AND SUBJECTS WITH HIGHER ADHERENCE RATES MAY BE FUNCTIONING CLOSER TO MAXIMUM ABILITY BEFORE THE INTERVENTION. STRATEGIES TO MAXIMIZE ADHERENCE AMONG SUBJECTS AT GREATER RISK FOR LOW ADHERENCE WILL BE IMPORTANT FOR FUTURE TRIALS, ESPECIALLY COMPLEMENTARY TREATMENTS REQUIRING GREATER EFFORT THAN SIMPLE PILL-TAKING.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
16 2754  47 YOGA PRACTICE PREDICTS IMPROVEMENTS IN DAY-TO-DAY PAIN IN WOMEN WITH METASTATIC BREAST CANCER. CONTEXT: WOMEN WITH METASTATIC BREAST CANCER (MBC) EXPERIENCE A SIGNIFICANT SYMPTOM BURDEN, INCLUDING CANCER PAIN. YOGA IS A MIND-BODY DISCIPLINE THAT HAS SHOWN PROMISE FOR ALLEVIATING CANCER PAIN, BUT FEW STUDIES HAVE INCLUDED PATIENTS WITH METASTATIC DISEASE OR EXAMINED THE ACUTE EFFECTS OF YOGA PRACTICE. OBJECTIVES: TO DETERMINE WHETHER DAILY PAIN CHANGED SIGNIFICANTLY DURING A RANDOMIZED CONTROLLED TRIAL OF THE MINDFUL YOGA PROGRAM AMONG WOMEN WITH MBC AND WHETHER TIME SPENT IN YOGA PRACTICE WAS RELATED TO DAILY PAIN. METHODS: ON ALTERNATE WEEKS DURING THE INTERVENTION PERIOD, WE COLLECTED DAILY MEASURES OF PAIN FROM A SUBSET OF 48 WOMEN RANDOMIZED TO EITHER YOGA (N = 30) OR A SUPPORT GROUP CONDITION (N = 18). WE ALSO ASSESSED DAILY DURATION OF YOGA PRACTICE AMONG PATIENTS RANDOMIZED TO YOGA. RESULTS: PAIN LEVELS WERE LOW FOR WOMEN IN BOTH CONDITIONS, AND NO DIFFERENTIAL TREATMENT EFFECTS WERE FOUND ON DAILY PAIN. HOWEVER, AMONG WOMEN RANDOMIZED TO YOGA, A DOSE/RESPONSE RELATIONSHIP WAS FOUND BETWEEN YOGA PRACTICE DURATION AND DAILY PAIN. WHEN PATIENTS HAD SPENT RELATIVELY MORE TIME PRACTICING YOGA ACROSS TWO CONSECUTIVE DAYS, THEY WERE MORE LIKELY TO EXPERIENCE LOWER PAIN ON THE NEXT DAY. THIS FINDING IS CONSISTENT WITH AN EARLIER MBC STUDY. MEDITATION PRACTICE SHOWED THE STRONGEST ASSOCIATION WITH LOWER DAILY PAIN. CONCLUSION: FINDINGS SUGGEST THAT YOGA PRACTICE (MEDITATION PRACTICE IN PARTICULAR) IS ASSOCIATED WITH ACUTE IMPROVEMENTS IN CANCER PAIN, AND THAT YOGA INTERVENTIONS MAY BE MORE IMPACTFUL IF TESTED IN A SAMPLE OF PATIENTS WITH ADVANCED CANCER IN WHICH PAIN IS RELATIVELY ELEVATED.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
17 1413  31 IMPLEMENTING YOGA INTO THE MANAGEMENT OF PATIENTS WITH REFRACTORY LOW BACK PAIN IN AN OUTPATIENT CLINIC SETTING. PURPOSE: TO EVALUATE THE EFFECTIVENESS OF IMPLEMENTING YOGA INTO THE TREATMENT OF PATIENTS WITH CHRONIC LOW BACK PAIN. DESIGN: QUANTITATIVE ANALYSIS WITH OPPORTUNITY FOR QUALITATIVE FEEDBACK. METHOD: EFFECTIVENESS OF THIS COMPLEMENTARY TREATMENT WAS ASSESSED USING A PRETEST/POSTTEST DESIGN OF PATIENTS WHO VOLUNTEERED TO PARTICIPATE IN YOGA CLASSES AS PART OF THEIR BACK PAIN MANAGEMENT. MEASUREMENTS INCLUDED LOW BACK PAIN RATING, PERCEPTION OF BACK PAIN INTERFERENCE WITH DAILY ACTIVITIES, AND SELF-EFFICACY IN DEALING WITH CHRONIC LOW BACK PAIN. FINDINGS: ALTHOUGH NO STATISTICALLY SIGNIFICANT FINDINGS WERE FOUND DUE TO THE SMALL SAMPLE SIZE, MOST PARTICIPANTS DEMONSTRATED IMPROVED INDIVIDUAL SCORES ON ALL MEASUREMENT SURVEYS INCLUDING QUALITATIVE COMMENTS. CONCLUSION: BASED ON THE FINDINGS OF THIS PILOT STUDY, FURTHER STUDIES ON IMPLEMENTING YOGA INTO THE TREATMENT OF CHRONIC LOW BACK PAIN ARE ENCOURAGED.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
18 2579  36 YOGA FOR HEALTH-RELATED QUALITY OF LIFE IN ADULT CANCER: A RANDOMIZED CONTROLLED FEASIBILITY STUDY. AN INCREASE IN PATIENT-LED UPTAKE OF COMPLEMENTARY THERAPIES IN ADULT CANCER HAS LED TO A NEED FOR MORE RIGOROUS STUDY OF SUCH INTERVENTIONS AND THEIR OUTCOMES. THIS STUDY THEREFORE AIMED TO EVALUATE THE FEASIBILITY AND ACCEPTABILITY OF A YOGA INTERVENTION IN MEN AND WOMEN RECEIVING CONVENTIONAL TREATMENT FOR A CANCER DIAGNOSIS. PROSPECTIVE, MIXED METHODS FEASIBILITY TRIAL ALLOCATED PARTICIPANTS TO RECEIVE ONE OF THREE YOGA INTERVENTIONS OVER A FOUR-WEEK STUDY PERIOD. DATA COLLECTION WAS COMPLETED THROUGH ONLINE SURVEY OF QOL-CA/CS AND CUSTOMIZED SURVEYS. FIFTEEN PARTICIPANTS WERE INCLUDED (11 FEMALE) UNDERGOING TREATMENT FOR BREAST, PROSTATE, COLORECTAL, BRAIN, AND BLOOD AND LUNG CANCER. TWO PARTICIPANTS DROPPED OUT AND COMPLETE QUALITATIVE AND QUANTITATIVE DATA SETS WERE COLLECTED FROM 12 PARTICIPANTS AND FOUR YOGA INSTRUCTORS. OTHER OUTCOME MEASURES INCLUDED IMPLEMENTATION COSTS PATIENT-REPORTED PREFERENCES FOR YOGA INTERVENTION AND CHANGES IN QOL-CA/CS. THREE TYPES OF YOGA INTERVENTION WERE SAFELY ADMINISTERED IN ADULT CANCER. MIXED METHODS, COST-EFFICIENCY, QOL-CA/CS, AND EVIDENCE-BASED DESIGN OF YOGA INTERVENTION HAVE BEEN USED TO ESTABLISH FEASIBILITY AND PATIENT-PREFERENCES FOR YOGA DELIVERY IN ADULT CANER. RESULTS SUGGEST THAT, WITH SOME METHODOLOGICAL IMPROVEMENTS, A LARGE-SCALE RANDOMIZED CONTROLLED TRIAL IS WARRANTED TO TEST THE EFFICACY OF YOGA FOR MALE AND FEMALE CANCER PATIENTS. THIS TRIAL IS REGISTERED WITH CLINICALTRIALS.GOV NCT02309112.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
19 1617  48 MINDFUL YOGA FOR WOMEN WITH METASTATIC BREAST CANCER: DESIGN OF A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: WOMEN WITH METASTATIC BREAST CANCER (MBC) HAVE AVERAGE LIFE EXPECTANCIES OF ABOUT 2 YEARS, AND REPORT HIGH LEVELS OF DISEASE-RELATED SYMPTOMS INCLUDING PAIN, FATIGUE, SLEEP DISTURBANCE, PSYCHOLOGICAL DISTRESS, AND FUNCTIONAL IMPAIRMENT. THERE IS GROWING RECOGNITION OF THE LIMITATIONS OF MEDICAL APPROACHES TO MANAGING SUCH SYMPTOMS. YOGA IS A MIND-BODY DISCIPLINE THAT HAS DEMONSTRATED A POSITIVE IMPACT ON PSYCHOLOGICAL AND FUNCTIONAL HEALTH IN EARLY STAGE BREAST CANCER PATIENTS AND SURVIVORS, BUT HAS NOT BEEN RIGOROUSLY STUDIED IN ADVANCED CANCER SAMPLES. METHODS: THIS RANDOMIZED CONTROLLED TRIAL EXAMINES THE FEASIBILITY AND INITIAL EFFICACY OF A MINDFUL YOGA PROGRAM, COMPARED WITH A SOCIAL SUPPORT CONDITION THAT CONTROLS FOR ATTENTION, ON MEASURES OF DISEASE-RELATED SYMPTOMS SUCH AS PAIN AND FATIGUE. THE STUDY WILL BE COMPLETED BY DECEMBER 2017. SIXTY-FIVE WOMEN WITH MBC AGE >/= 18 ARE BEING IDENTIFIED AND RANDOMIZED WITH A 2:1 ALLOCATION TO MINDFUL YOGA OR A SUPPORT GROUP CONTROL INTERVENTION. THE 120-MIN INTERVENTION SESSIONS TAKE PLACE WEEKLY FOR 8 WEEKS. THE STUDY IS CONDUCTED AT AN URBAN TERTIARY CARE ACADEMIC MEDICAL CENTER LOCATED IN DURHAM, NORTH CAROLINA. THE PRIMARY FEASIBILITY OUTCOME IS ATTENDANCE AT INTERVENTION SESSIONS. EFFICACY OUTCOMES INCLUDE PAIN, FATIGUE, SLEEP QUALITY, PSYCHOLOGICAL DISTRESS, MINDFULNESS AND FUNCTIONAL CAPACITY AT POST-INTERVENTION, 3-MONTH FOLLOW-UP, AND 6-MONTH FOLLOW-UP. DISCUSSION: IN THIS ARTICLE, WE PRESENT THE CHALLENGES OF DESIGNING A RANDOMIZED CONTROLLED TRIAL WITH LONG-TERM FOLLOW-UP AMONG WOMEN WITH MBC. THESE CHALLENGES INCLUDE ENSURING ADEQUATE RECRUITMENT INCLUDING OF MINORITIES, LIMITING AND CONTROLLING FOR SELECTION BIAS, TAILORING OF THE YOGA INTERVENTION TO ADDRESS SPECIAL NEEDS, AND MAXIMIZING ADHERENCE AND RETENTION. THIS PROJECT WILL PROVIDE IMPORTANT INFORMATION REGARDING YOGA AS AN INTERVENTION FOR WOMEN WITH ADVANCED CANCER, INCLUDING PRELIMINARY DATA ON THE PSYCHOLOGICAL AND FUNCTIONAL EFFECTS OF YOGA FOR MBC PATIENTS. THIS INVESTIGATION WILL ALSO ESTABLISH RIGOROUS METHODS FOR FUTURE RESEARCH INTO YOGA AS AN INTERVENTION FOR THIS POPULATION. TRIAL REGISTRATION: CLINICALTRIALS.GOV IDENTIFER: NCT01927081 , REGISTERED AUGUST 16, 2013.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                       
20   87  42 A MIXED METHODS EVALUATION OF AN INDIVIDUALISED YOGA THERAPY INTERVENTION FOR RHEUMATOID ARTHRITIS: PILOT STUDY. OBJECTIVES: TO EXPLORE PATIENTS' EXPERIENCES OF AN INDIVIDUALISED YOGA THERAPY INTERVENTION FOR RHEUMATOID ARTHRITIS (RA), SPECIFICALLY IN TERMS OF ITS ACCEPTABILITY AND IMPACT ON PATIENT-REPORTED OUTCOMES. DESIGN: TEN PATIENTS TOOK PART IN A 16 WEEK YOGA THERAPY INTERVENTION IN A HOSPITAL SETTING, CONSISTING OF 10 ONE-TO-ONE CONSULTATIONS WITH A YOGA THERAPIST FOLLOWED BY TWO GROUP REVIEW SESSIONS. CHANGES IN HEALTH (EQ-5D, HADS) WERE ASSESSED PRE- AND POST-INTERVENTION AND AT 12-MONTH FOLLOW-UP. IN-DEPTH INTERVIEWS WERE CONDUCTED POST-INTERVENTION AND ANALYSED USING THEMATIC ANALYSIS. RESULTS: ATTENDANCE OF THE 1-TO-1 SESSIONS WAS HIGH (98 %) AND ALL PARTICIPANTS REPORTED STRONG COMMITMENT TO THEIR PERSONALISED HOME PRACTICE. THERE WERE SIGNIFICANT IMPROVEMENTS IN MEASURES OF DEPRESSION, ANXIETY, PAIN, QUALITY OF LIFE AND GENERAL HEALTH AT POST-INTERVENTION AND 12-MONTHS (P < 0.05). IN INTERVIEWS, ALL BUT ONE PARTICIPANT REPORTED POSITIVE CHANGES TO THEIR SYMPTOMS AND SEVERAL REPORTED REDUCTIONS IN THEIR MEDICATION AND BROADER BENEFITS SUCH AS IMPROVED SLEEP, MOOD AND ENERGY, ENABLING RE-ENGAGEMENT WITH LIFE. THE PERSONALLY TAILORED NATURE OF THE PRACTICE AND PERCEIVED BENEFITS WERE KEY MOTIVATIONAL FACTORS. PARTICULAR VALUE WAS PLACED ON THE THERAPEUTIC FUNCTION OF THE CONSULTATION AND PROVISION OF TOOLS TO MANAGE STRESS AND BUILD RESILIENCE. CONCLUSION: THIS YOGA THERAPY INTERVENTION WAS POSITIVELY RECEIVED BY PATIENTS WITH RA, WITH HIGH LEVELS OF ADHERENCE TO BOTH THE TREATMENTS AND TAILORED HOME PRACTICE. THE FINDINGS SUGGEST THAT YOGA THERAPY HAS POTENTIAL AS AN ADJUNCT THERAPY TO IMPROVE RA SYMPTOMS, INCREASE SELF-CARE BEHAVIOURS AND MANAGE STRESS AND NEGATIVE AFFECT SUCH AS ANXIETY. A LARGER MULTI-CENTRE STUDY IS THEREFORE WARRANTED.	2020