1 1038 130 EFFECTS OF YOGA IN PATIENTS WITH CHRONIC HEART FAILURE: A META-ANALYSIS. THE USE OF YOGA AS AN EFFECTIVE CARDIAC REHABILITATION IN PATIENTS WITH CHRONIC HEART FAILURE (CHF) REMAINS CONTROVERSIAL. WE PERFORMED A META-ANALYSIS TO EXAMINE THE EFFECTS OF YOGA ON EXERCISE CAPACITY AND HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN PATIENTS WITH CHF. METHODS: WE SEARCHED MEDLINE, COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS, EXCERPTA MEDICA DATABASE, LILACS, PHYSIOTHERAPY EVIDENCE DATABASE, THE SCIENTIFIC ELECTRONIC LIBRARY ONLINE, AND CUMULATIVE INDEX TO NURSING AND ALLIED HEALTH (FROM THE EARLIEST DATE AVAILABLE TO DECEMBER 2013) FOR RANDOMIZED CONTROLLED TRIALS (RCTS) EXAMINING THE EFFECTS OF YOGA VERSUS EXERCISE AND/OR OF YOGA VERSUS CONTROL ON EXERCISE CAPACITY (PEAKVO2) AND QUALITY-OF-LIFE (HRQOL) IN CHF. TWO REVIEWERS SELECTED STUDIES INDEPENDENTLY. WEIGHTED MEAN DIFFERENCES (WMDS) AND 95% CONFIDENCE INTERVALS (CIS) WERE CALCULATED, AND HETEROGENEITY WAS ASSESSED USING THE I2 TEST. TWO STUDIES MET THE SELECTION CRITERIA (TOTAL: 30 YOGA AND 29 CONTROL PATIENTS). THE RESULTS SUGGESTED THAT YOGA COMPARED WITH CONTROL HAD A POSITIVE IMPACT ON PEAK VO2 AND HRQOL. PEAK VO2, WMD (3.87 95% CI: 1.95 TO 5.80), AND GLOBAL HRQOL STANDARDIZED MEAN DIFFERENCES (-12.46 95% CI: -22.49 TO -2.43) IMPROVED IN THE YOGA GROUP COMPARED TO THE CONTROL GROUP. YOGA ENHANCES PEAK VO2 AND HRQOL IN PATIENTS WITH CHF AND COULD BE CONSIDERED FOR INCLUSION IN CARDIAC REHABILITATION PROGRAMS. LARGER RCTS ARE REQUIRED TO FURTHER INVESTIGATE THE EFFECTS OF YOGA IN PATIENTS WITH CHF.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
2 1065  47 EFFECTS OF YOGA ON IMPROVING QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: COMPLICATIONS OF BREAST CANCER TREATMENT CAN CAUSE PHYSICAL AND PSYCHOSOCIAL DISTRESS IN PATIENTS. YOGA DEMONSTRATES SUBSTANTIAL POTENTIAL AS A SUPPORTIVE THERAPY FOR PATIENTS WITH BREAST CANCER. OUR AIM IS TO CONDUCT A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS TO EVALUATE THE EFFECTIVENESS OF YOGA IN ENHANCING THE QUALITY OF LIFE (QOL) OF PATIENTS WITH BREAST CANCER. METHODS: WE SEARCHED FOR STUDIES PUBLISHED BEFORE MARCH 2020 IN THE PUBMED, EMBASE, AND COCHRANE LIBRARY DATABASES. INDIVIDUAL EFFECT SIZES WERE STANDARDIZED, AND THE POOLED EFFECT SIZE WAS CALCULATED USING A RANDOM EFFECT MODEL. MEASURED OUTCOMES INCLUDED QOL, ANXIETY AND DEPRESSION, STRESS, FATIGUE, PAIN SEVERITY, AND SLEEP QUALITY. RESULTS: IN TOTAL, 26 TRIALS INVOLVING 2069 PATIENTS WERE REVIEWED. SIGNIFICANT ENHANCEMENT IN QOL WAS OBSERVED IMMEDIATELY AFTER THE YOGA INTERVENTION. THE POOLED MEAN DIFFERENCES IN SOCIAL (WEIGHTED MEAN DIFFERENCE [WMD]: 1.36, 95% CONFIDENCE INTERVAL [CI] 0.12-2.61), EMOTIONAL (WMD: 1.46, 95% CI 0.26-2.66), AND FUNCTIONAL WELL-BEING (WMD: 2.04, 95% CI 0.21-3.87) WERE SIGNIFICANTLY HIGHER IN THE YOGA GROUP THAN IN THE CONTROL GROUP. PATIENTS PRACTICING YOGA EXHIBITED SIGNIFICANT IMPROVEMENTS IN PHYSICAL WELL-BEING, MENTAL WELL-BEING, AND SLEEP QUALITY AS WELL AS REDUCTIONS IN ANXIETY, DEPRESSION, STRESS, FATIGUE, AND PAIN SEVERITY AFTER THE INTERVENTION. CONCLUSIONS: YOGA MAY ENHANCE QOL IN PATIENTS WITH BREAST CANCER EXPERIENCING POST-TREATMENT COMPLICATIONS. THEREFORE, WE RECOMMEND YOGA AS A SUPPORTIVE THERAPY FOR PATIENTS WITH BREAST CANCER TO RELIEVE POST-TREATMENT DISTRESS.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
3 2859  49 YOGA-BASED EXERCISE IMPROVES BALANCE AND MOBILITY IN PEOPLE AGED 60 AND OVER: A SYSTEMATIC REVIEW AND META-ANALYSIS. OBJECTIVE: ONE-THIRD OF COMMUNITY-DWELLING OLDER ADULTS FALL ANNUALLY. EXERCISE THAT CHALLENGES BALANCE IS PROVEN TO PREVENT FALLS. WE CONDUCTED A SYSTEMATIC REVIEW WITH META-ANALYSIS TO DETERMINE THE IMPACT OF YOGA-BASED EXERCISE ON BALANCE AND PHYSICAL MOBILITY IN PEOPLE AGED 60+ YEARS. METHODS: SEARCHES FOR RELEVANT TRIALS WERE CONDUCTED ON THE FOLLOWING ELECTRONIC DATABASES: MEDLINE, EMBASE, COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS, CINAHL, ALLIED AND COMPLEMENTARY MEDICINE DATABASE AND THE PHYSIOTHERAPY EVIDENCE DATABASE (PEDRO) FROM INCEPTION TO FEBRUARY 2015. TRIALS WERE INCLUDED IF THEY EVALUATED THE EFFECT OF PHYSICAL YOGA (EXCLUDING MEDITATION AND BREATHING EXERCISES ALONE) ON BALANCE IN PEOPLE AGED 60+ YEARS. WE EXTRACTED DATA ON BALANCE AND THE SECONDARY OUTCOME OF PHYSICAL MOBILITY. STANDARDISED MEAN DIFFERENCES AND 95% CONFIDENCE INTERVALS (CI) WERE CALCULATED USING RANDOM-EFFECTS MODELS. METHODOLOGICAL QUALITY OF TRIALS WAS ASSESSED USING THE 10-POINT PHYSIOTHERAPY EVIDENCE DATABASE (PEDRO) SCALE. RESULTS: SIX TRIALS OF RELATIVELY HIGH METHODOLOGICAL QUALITY, TOTALLING 307 PARTICIPANTS, WERE IDENTIFIED AND HAD DATA THAT COULD BE INCLUDED IN A META-ANALYSIS. OVERALL, YOGA INTERVENTIONS HAD A SMALL EFFECT ON BALANCE PERFORMANCE (HEDGES' G = 0.40, 95% CI 0.15-0.65, 6 TRIALS) AND A MEDIUM EFFECT ON PHYSICAL MOBILITY (HEDGES' G = 0.50, 95% CI 0.06-0.95, 3 TRIALS). CONCLUSION: YOGA INTERVENTIONS RESULTED IN SMALL IMPROVEMENTS IN BALANCE AND MEDIUM IMPROVEMENTS IN PHYSICAL MOBILITY IN PEOPLE AGED 60+ YEARS. FURTHER RESEARCH IS REQUIRED TO DETERMINE WHETHER YOGA-RELATED IMPROVEMENTS IN BALANCE AND MOBILITY TRANSLATE TO PREVENTION OF FALLS IN OLDER PEOPLE. PROSPERO REGISTRATION NUMBER CRD42015015872.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
4 2683  48 YOGA IN THE MANAGEMENT OF CHRONIC DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: HEART DISEASE, STROKE, AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) ARE THE LEADING CAUSES OF DEATH AND DISABILITY WORLDWIDE. ALTHOUGH INDIVIDUALS WITH THESE CONDITIONS HAVE BEEN REPORTED TO BENEFIT FROM YOGA, ITS EFFECTIVENESS REMAINS UNCLEAR. OBJECTIVE: TO PERFORM A SYSTEMATIC REVIEW OF THE EFFECTIVENESS OF YOGA ON EXERCISE CAPACITY, HEALTH RELATED QUALITY OF LIFE (HRQL), AND PSYCHOLOGICAL WELL-BEING FOR INDIVIDUALS WITH CHRONIC DISEASE AND DESCRIBE THE STRUCTURE AND DELIVERY OF PROGRAMS. RESEARCH DESIGN: WE PERFORMED A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS EXAMINING YOGA PROGRAMS FOR INDIVIDUALS WITH HEART DISEASE, STROKE, AND COPD COMPARED WITH USUAL CARE. QUALITY WAS ASSESSED USING THE COCHRANE RISK OF BIAS TOOL. META-ANALYSES WERE CONDUCTED USING REVIEW MANAGER 5.3. THE PROTOCOL WAS REGISTERED ON PROSPERO (CRD42014014589). RESULTS: TEN STUDIES (431 INDIVIDUALS, MEAN AGE 56+/-8 Y) WERE INCLUDED AND WERE COMPARABLE IN THEIR DESIGN AND COMPONENTS, IRRESPECTIVE OF THE CHRONIC DISEASE. THE STANDARDIZED MEAN DIFFERENCE FOR THE MEAN CHANGE IN EXERCISE CAPACITY WAS 2.69 (95% CONFIDENCE INTERVAL, 1.39-3.99) AND FOR HRQL IT WAS 1.24 (95% CONFIDENCE INTERVAL, -0.37 TO 2.85). SYMPTOMS OF ANXIETY WERE REDUCED AFTER YOGA IN INDIVIDUALS WITH STROKE, ALTHOUGH THIS WAS NOT OBSERVED IN INDIVIDUALS WITH COPD. THE EFFECT OF YOGA ON SYMPTOMS OF DEPRESSION VARIED ACROSS STUDIES WITH NO SIGNIFICANT EFFECTS COMPARED WITH USUAL CARE. CONCLUSIONS: YOGA PROGRAMS HAVE SIMILAR DESIGNS AND COMPONENTS ACROSS CHRONIC DISEASE POPULATIONS. COMPARED WITH USUAL CARE, YOGA RESULTED IN SIGNIFICANT IMPROVEMENTS IN EXERCISE CAPACITY AND A MEAN IMPROVEMENT IN HRQL. YOGA PROGRAMS MAY BE A USEFUL ADJUNCT TO FORMAL REHABILITATION PROGRAMS.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
5 1043  40 EFFECTS OF YOGA INTERVENTIONS ON FATIGUE: A META-ANALYSIS. BACKGROUND. RESEARCHERS AIMED AT SYSTEMATICALLY REVIEWING AND META-ANALYZING THE EFFECTIVENESS OF YOGA INTERVENTIONS FOR FATIGUE. METHODS. PUBMED/MEDLINE WAS SEARCHED UNTIL JANUARY 2012 FOR CONTROLLED CLINICAL STUDIES. TWO REVIEWERS INDEPENDENTLY EXTRACTED THE DATA. THE METHODOLOGICAL QUALITY OF THE STUDIES WAS ASSESSED. A META-ANALYSIS WAS PERFORMED. RESULTS. NINETEEN CLINICAL STUDIES (TOTAL N = 948) WERE INCLUDED IN THIS REVIEW. INVESTIGATED YOGA STYLES INCLUDED HATHA, IYENGAR, ASANAS, PATANJALI, SAHAJA, AND TIBETAN YOGA. PARTICIPANTS WERE SUFFERING FROM CANCER, MULTIPLE SCLEROSIS, DIALYSIS, CHRONIC PANCREATITIS, FIBROMYALGIA, ASTHMA, OR WERE HEALTHY. YOGA HAD A SMALL POSITIVE EFFECT ON FATIGUE (SMD = 0.27, 59% CI = 0.23-0.31). SEVEN STUDIES RECEIVED 4 POINTS ON THE JADAD SCORE. THERE WERE BASELINE DIFFERENCES IN AT LEAST 5 STUDIES. CONCLUSION. OVERALL, THE EFFECTS OF YOGA INTERVENTIONS ON FATIGUE WERE ONLY SMALL, PARTICULARLY IN CANCER PATIENTS. ALTHOUGH YOGA IS GENERALLY A SAFE THERAPEUTIC INTERVENTION AND EFFECTIVE TO ATTENUATE OTHER HEALTH-RELATED SYMPTOMS, THIS META-ANALYSIS WAS NOT ABLE TO DEFINE THE POWERFUL EFFECT OF YOGA ON PATIENTS SUFFERING FROM FATIGUE. TREATMENT EFFECTS OF YOGA COULD BE IMPROVED IN WELL-DESIGNED FUTURE STUDIES. ACCORDING TO THE GRADE RECOMMENDATIONS ASSESSING THE OVERALL QUALITY OF EVIDENCE, THERE IS A MODERATE EFFECT OF THE CONFIDENCE PLACED IN THE ESTIMATES OF THE EFFECTS DISCUSSED HERE.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
6 2271  48 THE RISKS AND BENEFITS OF YOGA FOR PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS. OBJECTIVES: TO DETERMINE THE EFFECTIVENESS AND SAFETY OF YOGA INTERVENTIONS ON DISEASE SYMPTOMS, QUALITY OF LIFE AND FUNCTION IN PATIENTS DIAGNOSED WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD). DATA SOURCES: MEDLINE/PUBMED, SCOPUS, AND CENTRAL (COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS) WERE SEARCHED THROUGH 6 JUNE 2019. REVIEW METHODS: RANDOMIZED CONTROLLED TRIALS ASSESSING THE EFFECTS OF YOGA ON QUALITY OF LIFE, DYSPNEA, EXERCISE CAPACITY, AND PULMONARY FUNCTION (FEV1) IN PATIENTS WITH COPD WERE INCLUDED. SAFETY WAS DEFINED AS SECONDARY OUTCOME. MEAN DIFFERENCES (MD) AND STANDARDIZED MEAN DIFFERENCES (SMD) WITH 95% CONFIDENCE INTERVALS (CIS) WERE COMPUTED. RISK OF BIAS WAS ASSESSED USING THE COCHRANE TOOL. RESULTS: ELEVEN RANDOMIZED CONTROLLED TRIALS WITH A TOTAL OF 586 PATIENTS WERE INCLUDED. META-ANALYSIS REVEALED EVIDENCE FOR EFFECTS OF YOGA COMPARED TO NO TREATMENT ON QUALITY OF LIFE ON THE COPD ASSESSMENT TEST (MD = 3.81; 95% CI = 0.97 TO 6.65; P = 0.009, I(2) = 70%), EXERCISE CAPACITY ASSESSED BY THE 6-MINUTE WALK TEST (MD = 25.53 M; 95% CI = 12.16 M TO 38.90 M; P = 0.001, I(2) = 0%), AND PULMONARY FUNCTION ASSESSED BY FEV1 PREDICTED (MD = 3.95%; 95% CI = 2.74% TO 5.17%; P < 0.001, I(2) = 0%). ONLY THE EFFECTS ON EXERCISE CAPACITY AND PULMONARY FUNCTION WERE ROBUST AGAINST METHODOLOGICAL BIAS. EFFECTS WERE ONLY PRESENT IN BREATHING-FOCUSED YOGA INTERVENTIONS BUT NOT IN INTERVENTIONS INCLUDING YOGA POSTURES. ADVERSE EVENTS WERE REPORTED INFREQUENTLY. CONCLUSION: THIS META-ANALYSIS FOUND ROBUST EFFECTS OF YOGA ON EXERCISE CAPACITY AND PULMONARY FUNCTION IN PATIENTS WITH COPD. YOGA, SPECIFICALLY YOGA BREATHING TECHNIQUES, CAN BE AN EFFECTIVE ADJUNCT INTERVENTION FOR PATIENTS WITH COPD. YOGA'S SAFETY NEEDS TO BE ASSESSED IN MORE DEPTH IN FUTURE STUDIES.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
7  231  40 A SYSTEMATIC REVIEW OF YOGA FOR HEART DISEASE. BACKGROUND: THIS SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS (RCTS) AIMED TO EVALUATE THE QUALITY OF EVIDENCE AND THE STRENGTH OF RECOMMENDATION FOR YOGA AS AN ANCILLARY INTERVENTION FOR HEART DISEASE. METHODS: MEDLINE/PUBMED, SCOPUS, THE COCHRANE LIBRARY, AND INDMED WERE SEARCHED UP TO OCTOBER 2013. MAIN OUTCOME MEASURES WERE MORTALITY, NONFATAL CARDIAC EVENTS, EXERCISE CAPACITY, HEALTH-RELATED QUALITY OF LIFE, AND MODIFIABLE CARDIAC RISK FACTORS. RISK OF BIAS, QUALITY OF EVIDENCE, AND THE STRENGTH OF THE RECOMMENDATION FOR OR AGAINST YOGA WERE ASSESSED ACCORDING TO THE COCHRANE COLLABORATION AND GRADE RECOMMENDATIONS. RESULTS: SEVEN RCTS WITH 624 PATIENTS COMPARING YOGA TO USUAL CARE WERE INCLUDED. FOR CORONARY HEART DISEASE (FOUR RCTS), THERE WAS VERY LOW EVIDENCE FOR NO EFFECT ON MORTALITY, FOR A REDUCED NUMBER OF ANGINA EPISODES, AND FOR INCREASED EXERCISE CAPACITY, AND LOW EVIDENCE FOR REDUCED MODIFIABLE CARDIAC RISK FACTORS. FOR HEART FAILURE (TWO RCTS), THERE WAS VERY LOW EVIDENCE FOR NO EFFECT ON MORTALITY, AND LOW EVIDENCE FOR INCREASED EXERCISE CAPACITY, AND FOR NO EFFECT ON HEALTH-RELATED QUALITY OF LIFE. FOR CARDIAC DYSRHYTHMIAS TREATED WITH IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR (ONE RCT), THERE WAS VERY LOW EVIDENCE FOR NO EFFECT ON MORTALITY, AND FOR IMPROVED QUALITY, AND LOW EVIDENCE FOR EFFECTS ON NONFATAL DEVICE-TREATED VENTRICULAR EVENTS. THREE RCTS REPORTED SAFETY DATA AND REPORTED THAT NO ADVERSE EVENTS OCCURRED. CONCLUSIONS: BASED ON THE RESULTS OF THIS REVIEW, WEAK RECOMMENDATIONS CAN BE MADE FOR THE ANCILLARY USE OF YOGA FOR PATIENTS WITH CORONARY HEART DISEASE, HEART FAILURE, AND CARDIAC DYSRHYTHMIA AT THIS POINT.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
8 2365  30 WALKING IS MORE EFFECTIVE THAN YOGA AT REDUCING SLEEP DISTURBANCE IN CANCER PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. THIS REVIEW AIMED TO DETERMINE WHETHER WALKING IS MORE EFFECTIVE THAN YOGA AT IMPROVING SLEEP DISTURBANCE IN CANCER PATIENTS. A SYSTEMATIC SEARCH OF RANDOMIZED CONTROLLED TRIALS WAS PERFORMED IN THE PUBMED, EMBASE, CINAHL, COCHRANE LIBRARY, CNKI, AIRITI LIBRARY, AND OTHER HEALTH-RELATED DATABASES. TWENTY-FIVE STUDIES WERE IDENTIFIED WITH A TOTAL OF 1918 PARTICIPANTS. THE PITTSBURGH SLEEP QUALITY INDEX WAS THE MOST COMMONLY USED OUTCOME MEASUREMENT TOOL, AND MODERATE-INTENSITY WALKING WAS THE MOST FREQUENTLY USED INTERVENTION. THE MAJORITY OF THE INCLUDED SUBJECTS WERE BREAST CANCER PATIENTS. OVERALL, WALKING SIGNIFICANTLY IMPROVED SLEEP DISTURBANCE COMPARED TO YOGA (P = 0.01). STATISTICALLY SIGNIFICANT MODERATORS INCLUDED ADHERENCE RATE FOR WALKING (P < 0.001) AND ALLOCATION CONCEALMENT AND OUTCOME MEASUREMENT TOOL FOR YOGA (P = 0.04; P = 0.03). WE CONCLUDED THAT WALKING IS MORE EFFECTIVE THAN YOGA IN IMPROVING SLEEP DISTURBANCE IN CANCER PATIENTS. THUS, MODERATE-INTENSITY WALKING IS RECOMMENDED FOR CANCER PATIENTS WITH SLEEP DISTURBANCE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
9 1077  46 EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION AND QUALITY OF LIFE IN WOMEN WITH BREAST CANCER: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. OBJECTIVE: THE AIM OF THIS META-ANALYSIS WAS TO EVALUATE THE EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION AND QUALITY OF LIFE (QOL) IN WOMEN WITH BREAST CANCER. DESIGN: A SYSTEMATIC SEARCH OF PUBMED, EMBASE, THE COCHRANE LIBRARY, THE CHINESE BIOMEDICAL LITERATURE DATABASE, AND THE CHINESE DIGITAL JOURNALS FULL-TEXT DATABASE WAS CARRIED OUT. RANDOMIZED CONTROL TRIALS (RCTS) EXAMINING THE EFFECTS OF YOGA, VERSUS A CONTROL GROUP RECEIVING NO INTERVENTION, ON PSYCHOLOGIC FUNCTIONING AND QOL IN WOMEN WITH BREAST CANCER WERE INCLUDED. METHODOLOGICAL QUALITY OF INCLUDED RCTS WAS ASSESSED ACCORDING TO THE COCHRANE HANDBOOK FOR SYSTEMATIC REVIEWS OF INTERVENTIONS 5.0.1, AND DATA WERE ANALYZED USING THE COCHRANE COLLABORATION'S REVIEW MANAGER 5.1. RESULTS: SIX (6) STUDIES INVOLVING 382 PATIENTS WERE INCLUDED. THE META-ANALYSIS SHOWED THAT YOGA CAN IMPROVE QOL FOR WOMEN WITH BREAST CANCER. A STATISTICALLY SIGNIFICANT EFFECT FAVORING YOGA FOR THE OUTCOME OF QOL WAS FOUND (STANDARD MEAN DIFFERENCE=0.27, 95% CONFIDENCE INTERVAL [0.02, 0.52], P=0.03). ALTHOUGH THE EFFECTS OF YOGA ON PSYCHOLOGIC FUNCTION OUTCOMES--SUCH AS ANXIETY, DEPRESSION, DISTRESS AND SLEEP--WERE IN THE EXPECTED DIRECTION, THESE EFFECTS WERE NOT STATISTICALLY SIGNIFICANT (P>0.05). FATIGUE SHOWED NO SIGNIFICANT DIFFERENCE (P>0.05). CONCLUSIONS: THE PRESENT DATA PROVIDED LITTLE INDICATION OF HOW EFFECTIVE YOGA MIGHT BE WHEN THEY WERE APPLIED BY WOMEN WITH BREAST CANCER EXCEPT FOR MILDLY EFFECTIVE IN QOL IMPROVEMENT. THE FINDINGS WERE BASED ON A SMALL BODY OF EVIDENCE IN WHICH METHODOLOGICAL QUALITY WAS NOT HIGH. FURTHER WELL-DESIGNED RCTS WITH LARGE SAMPLE SIZE ARE NEEDED TO CLARIFY THE UTILITY OF YOGA PRACTICE FOR THIS POPULATION.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
10 2597  49 YOGA FOR MULTIPLE SCLEROSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. WHILE YOGA SEEMS TO BE EFFECTIVE IN A NUMBER OF NEUROPSYCHIATRIC DISORDERS, THE EVIDENCE OF EFFICACY IN MULTIPLE SCLEROSIS REMAINS UNCLEAR. THE AIM OF THIS REVIEW WAS TO SYSTEMATICALLY ASSESS AND META-ANALYZE THE AVAILABLE DATA ON EFFICACY AND SAFETY OF YOGA IN PATIENTS WITH MULTIPLE SCLEROSIS. MEDLINE/PUBMED, SCOPUS, THE COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS, PSYCINFO, CAM-QUEST, CAMBASE, AND INDMED WERE SEARCHED THROUGH MARCH 2014. RANDOMIZED CONTROLLED TRIALS (RCTS) OF YOGA FOR PATIENTS WITH MULTIPLE SCLEROSIS WERE INCLUDED IF THEY ASSESSED HEALTH-RELATED QUALITY OF LIFE, FATIGUE, AND/OR MOBILITY. MOOD, COGNITIVE FUNCTION, AND SAFETY WERE DEFINED AS SECONDARY OUTCOME MEASURES. RISK OF BIAS WAS ASSESSED USING THE COCHRANE TOOL. SEVEN RCTS WITH A TOTAL OF 670 PATIENTS WERE INCLUDED. EVIDENCE FOR SHORT-TERM EFFECTS OF YOGA COMPARED TO USUAL CARE WERE FOUND FOR FATIGUE (STANDARDIZED MEAN DIFFERENCE [SMD] = -0.52; 95% CONFIDENCE INTERVALS (CI) = -1.02 TO -0.02; P = 0.04; HETEROGENEITY: I2 = 60%; CHI2 = 7.43; P = 0.06) AND MOOD (SMD = -0.55; 95%CI = -0.96 TO -0.13; P = 0.01; HETEROGENEITY: I2 = 0%; CHI2 = 1.25; P = 0.53), BUT NOT FOR HEALTH-RELATED QUALITY OF LIFE, MUSCLE FUNCTION, OR COGNITIVE FUNCTION. THE EFFECTS ON FATIGUE AND MOOD WERE NOT ROBUST AGAINST BIAS. NO SHORT-TERM OR LONGER TERM EFFECTS OF YOGA COMPARED TO EXERCISE WERE FOUND. YOGA WAS NOT ASSOCIATED WITH SERIOUS ADVERSE EVENTS. IN CONCLUSION, SINCE NO METHODOLOGICAL SOUND EVIDENCE WAS FOUND, NO RECOMMENDATION CAN BE MADE REGARDING YOGA AS A ROUTINE INTERVENTION FOR PATIENTS WITH MULTIPLE SCLEROSIS. YOGA MIGHT BE CONSIDERED A TREATMENT OPTION FOR PATIENTS WHO ARE NOT ADHERENT TO RECOMMENDED EXERCISE REGIMENS.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
11 2079  39 THE EFFECT OF EXERCISE, YOGA AND PHYSIOTHERAPY ON THE QUALITY OF LIFE OF PEOPLE WITH MULTIPLE SCLEROSIS: SYSTEMATIC REVIEW AND META-ANALYSIS. INTRODUCTION: MULTIPLE SCLEROSIS (MS) IS A CHRONIC AUTOIMMUNE DISEASE AFFECTING THE MYELINATED AXONS OF THE CENTRAL NERVOUS SYSTEM CAUSING NEUROLOGICAL DETERIORATION. PEOPLE LIVING WITH MS HAVE A POOR QUALITY OF LIFE (QOL) BECAUSE OF THE SYMPTOMS CAUSED BY THE DISEASE AND THERE ARE VARIOUS TYPES OF TREATMENTS TO MANAGE THE SYMPTOMS ASIDE FROM MEDICATION. OBJECTIVE: THIS META-ANALYSIS EXAMINES THE EFFECT OF EXERCISE, YOGA AND PHYSIOTHERAPY ON THE PHYSICAL, MENTAL AND SOCIAL QOL AMONG INDIVIDUALS LIVING WITH MS. SETTING: A SYSTEMATIC REVIEW WITH META-ANALYSIS WAS CONDUCTED USING PUBMED, MEDLINE, AND SCOPUS FROM 1990 TO 2017. THE STANDARD MEAN DIFFERENCE SCORES WERE COMPUTED IN EACH STUDY FOR THE DOMAINS OF PHYSICAL, MENTAL AND SOCIAL FUNCTIONING. RESULTS: EIGHTEEN STUDIES MET THE INCLUSION CRITERIA FOR THIS META-ANALYSIS. AEROBIC EXERCISE WAS EFFECTIVE IN IMPROVING SATISFACTION WITH PHYSICAL FUNCTIONING,D = 0.35 (95% CI = 0.08 TO 0.62), MENTAL FUNCTIONING D = 0.42 (95% CI = 0.11 TO 0.72), AND SOCIAL FUNCTIONING D = 0.42 (95% CI = 0.15 TO 0.69). PHYSIOTHERAPY WAS ALSO FOUND TO BE EFFECTIVE FOR PHYSICAL FUNCTIONING D = 0.50 (95% CI 0.19 TO 0.80), MENTAL FUNCTIONING D = 0.44 (95% CI 0.14 TO 0.75) AND SOCIAL FUNCTIONING D = 0.60 (95% CI 0.21 TO 0.90). HOWEVER YOGA AND COMBINATION OF EXERCISES DID NOT HAVE A SIGNIFICANT EFFECT ON ANY OF THE QOL DOMAINS. CONCLUSION: THESE FINDINGS SUGGEST THAT AEROBIC EXERCISE AND PHYSIOTHERAPY IMPROVES THE SATISFACTION OF MS PATIENTS WITH THEIR PHYSICAL, MENTAL AND SOCIAL FUNCTIONING AND MAY BE INCLUDED AS NORMAL PRACTICE IN THE TREATMENT OF MS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
12 2330  35 TWELVE WEEKS OF YOGA FOR CHRONIC NONSPECIFIC LOWER BACK PAIN: A META-ANALYSIS. OBJECTIVES: TO INVESTIGATE THE OVERALL EFFECTS OF 12 WEEKS OF YOGA PRACTICE ON CHRONIC NONSPECIFIC LOWER BACK PAIN. METHODS: PUBMED, EMBASE, PSYCINFO, WEB OF SCIENCE, AND THE COCHRANE LIBRARY DATABASES WERE SEARCHED FROM INCEPTION TO FEBRUARY 9, 2019, AND SIX RANDOMIZED CONTROLLED TRIALS WERE SELECTED FOR THIS META-ANALYSIS. RESULTS: THE POOLED FIXED-EFFECT SIZE OF SIX TRIALS SHOWED THAT 12 WEEKS OF YOGA PROGRAMS COULD SIGNIFICANTLY REDUCE CHRONIC NONSPECIFIC LOWER BACK PAIN BY 0.41 WITHIN THE TRIALS (STANDARDIZED MEAN DIFFERENCE; 95% CONFIDENCE INTERVAL: -0.58 TO -0.23; P < .0001). SUBGROUP ANALYSES ALSO SHOWED THAT SIGNIFICANT PAIN REDUCTION WAS RELATED TO TYPE OF YOGA, LENGTH OF SESSION, STUDY QUALITY, AND TIMING OF PAIN ASSESSMENT. CONCLUSIONS: THESE FINDINGS REVEAL THAT 12 WEEKS OF YOGA CAN HELP ALLEVIATE PAIN, AND YOGA PROGRAMS SHOULD TAKE INTO ACCOUNT THE SUBGROUP FACTORS TO INCREASE INDIVIDUALS' RELIEF FROM CHRONIC NONSPECIFIC LOWER BACK PAIN.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
13 1055  37 EFFECTS OF YOGA ON CHRONIC NECK PAIN: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS. [PURPOSE] THE AIM OF THIS STUDY WAS TO INVESTIGATE THE EFFECTIVENESS OF YOGA IN THE MANAGEMENT OF CHRONIC NECK PAIN. [SUBJECTS AND METHODS] FIVE ELECTRONIC DATABASES WERE SEARCHED TO IDENTIFY RANDOMIZED CONTROLLED TRIALS (RCTS) OF YOGA INTERVENTION ON CHRONIC NECK PAIN. THE TRIALS WERE PUBLISHED IN THE ENGLISH LANGUAGE BETWEEN JANUARY 1966 AND DECEMBER 2015. THE COCHRANE RISK OF BIAS TOOL WAS USED TO ASSESS THE QUALITY OF THE TRIALS. [RESULTS] THREE TRIALS WERE IDENTIFIED AND INCLUDED IN THIS REVIEW. A CRITICAL APPRAISAL WAS PERFORMED ON THE TRIALS, AND THE RESULT INDICATED A HIGH RISK OF BIAS. A NARRATIVE DESCRIPTION WAS PROCESSED BECAUSE OF THE SMALL NUMBER OF RCTS. NECK PAIN INTENSITY AND FUNCTIONAL DISABILITY WERE SIGNIFICANTLY LOWER IN THE YOGA GROUPS THAN IN THE CONTROL GROUPS. [CONCLUSION] EVIDENCE FROM THE 3 RANDOMLY CONTROLLED TRIALS SHOWS THAT YOGA MAY BE BENEFICIAL FOR CHRONIC NECK PAIN. THE LOW-QUALITY RESULT OF THE CRITICAL APPRAISAL AND THE SMALL NUMBER OF TRIALS SUGGEST THAT HIGH-QUALITY RCTS ARE REQUIRED TO EXAMINE FURTHER THE EFFECTS OF YOGA INTERVENTION ON CHRONIC NECK PAIN RELIEF.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
14 2573  46 YOGA FOR ESSENTIAL HYPERTENSION: A SYSTEMATIC REVIEW. BACKGROUND: YOGA IS THOUGHT TO BE EFFECTIVE FOR HEALTH CONDITIONS. THE ARTICLE AIMS TO ASSESS THE CURRENT CLINICAL EVIDENCE OF YOGA FOR ESSENTIAL HYPERTENSION (EH). STRATEGY: MEDLINE, EMBASE, AND THE COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS (CENTRAL) IN THE COCHRANE LIBRARY WERE SEARCHED UNTIL JUNE, 2013. WE INCLUDED RANDOMIZED CLINICAL TRIALS TESTING YOGA AGAINST CONVENTIONAL THERAPY, YOGA VERSUS NO TREATMENT, YOGA COMBINED WITH CONVENTIONAL THERAPY VERSUS CONVENTIONAL THERAPY OR CONVENTIONAL THERAPY COMBINED WITH BREATH AWARENESS. STUDY SELECTION, DATA EXTRACTION, QUALITY ASSESSMENT, AND DATA ANALYSES WERE CONDUCTED ACCORDING TO THE COCHRANE STANDARDS. RESULTS: A TOTAL OF 6 STUDIES (INVOLVING 386 PATIENTS) WERE INCLUDED. THE METHODOLOGICAL QUALITY OF THE INCLUDED TRIALS WAS EVALUATED AS GENERALLY LOW. A TOTAL OF 6 RCTS MET ALL THE INCLUSION CRITERIA. 4 OF THEM COMPARED YOGA PLUS CONVENTIONAL THERAPY WITH CONVENTIONAL THERAPY. 1 RCT DESCRIBED YOGA COMBINED WITH CONVENTIONAL THERAPY VERSUS CONVENTIONAL THERAPY COMBINED WITH BREATH AWARENESS. 2 RCT TESTED THE EFFECT OF YOGA VERSUS CONVENTIONAL THERAPY ALONE. 1 RCT DESCRIBED YOGA COMPARED TO NO TREATMENT. ONLY ONE TRIAL REPORTED ADVERSE EVENTS WITHOUT DETAILS, THE SAFETY OF YOGA IS STILL UNCERTAIN. CONCLUSIONS: THERE IS SOME ENCOURAGING EVIDENCE OF YOGA FOR LOWERING SBP AND DBP. HOWEVER, DUE TO LOW METHODOLOGICAL QUALITY OF THESE IDENTIFIED TRIALS, A DEFINITE CONCLUSION ABOUT THE EFFICACY AND SAFETY OF YOGA ON EH CANNOT BE DRAWN FROM THIS REVIEW. THEREFORE, FURTHER THOROUGH INVESTIGATION, LARGE-SCALE, PROPER STUDY DESIGNED, RANDOMIZED TRIALS OF YOGA FOR HYPERTENSION WILL BE REQUIRED TO JUSTIFY THE EFFECTS REPORTED HERE.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
15 2144  38 THE EFFECTS OF MEDITATION, YOGA, AND MINDFULNESS ON DEPRESSION, ANXIETY, AND STRESS IN TERTIARY EDUCATION STUDENTS: A META-ANALYSIS. BACKGROUND: MEDITATION, YOGA, AND MINDFULNESS ARE POPULAR INTERVENTIONS AT UNIVERSITIES AND TERTIARY EDUCATION INSTITUTES TO IMPROVE MENTAL HEALTH. HOWEVER, THE EFFECTS ON DEPRESSION, ANXIETY, AND STRESS ARE UNCLEAR. THIS STUDY ASSESSED THE EFFECTIVENESS OF MEDITATION, YOGA, AND MINDFULNESS ON SYMPTOMS OF DEPRESSION, ANXIETY, AND STRESS IN TERTIARY EDUCATION STUDENTS. METHODS: WE SEARCHED COCHRANE CENTRAL REGISTER OF CONTROLLED TRIALS (CENTRAL), PUBMED, PSYCINFO AND IDENTIFIED 11,936 ARTICLES. AFTER RETRIEVING 181 PAPERS FOR FULL-TEXT SCREENING, 24 RANDOMIZED CONTROLLED TRIALS WERE INCLUDED IN THE QUALITATIVE ANALYSIS. WE CONDUCTED A RANDOM-EFFECTS META-ANALYSIS AMONGST 23 STUDIES WITH 1,373 PARTICIPANTS. RESULTS: AT POST-TEST, AFTER EXCLUSION OF OUTLIERS, EFFECT SIZES FOR DEPRESSION, G = 0.42 (95% CI: 0.16-0.69), ANXIETY G = 0.46 (95% CI: 0.34-0.59), STRESS G = 0.42 (95% CI: 0.27-0.57) WERE MODERATE. HETEROGENEITY WAS LOW (I (2) = 6%). WHEN COMPARED TO ACTIVE CONTROL, THE EFFECT DECREASED TO G = 0.13 (95% CI: -0.18-0.43). NO RCT REPORTED ON SAFETY, ONLY TWO STUDIES REPORTED ON ACADEMIC ACHIEVEMENT, MOST STUDIES HAD A HIGH RISK OF BIAS. CONCLUSIONS: MOST STUDIES WERE OF POOR QUALITY AND RESULTS SHOULD BE INTERPRETED WITH CAUTION. OVERALL MODERATE EFFECTS WERE FOUND WHICH DECREASED SUBSTANTIALLY WHEN INTERVENTIONS WERE COMPARED TO ACTIVE CONTROL. IT IS UNCLEAR WHETHER MEDITATION, YOGA OR MINDFULNESS AFFECT ACADEMIC ACHIEVEMENT OR AFFECT HAVE ANY NEGATIVE SIDE EFFECTS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
16 1299  43 HATHA YOGA FOR ACUTE, CHRONIC AND/OR TREATMENT-RESISTANT MOOD AND ANXIETY DISORDERS: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: THE AIM OF THIS STUDY WAS TO SYSTEMATICALLY INVESTIGATE THE EFFECTIVENESS OF HATHA YOGA IN TREATING ACUTE, CHRONIC AND/OR TREATMENT-RESISTANT MOOD AND ANXIETY DISORDERS. METHODS: MEDLINE, COCHRANE LIBRARY, CURRENT CONTROLLED TRIALS, CLINICAL TRIALS.GOV, NHR CENTRE FOR REVIEWS AND DISSEMINATION, PSYCINFO AND CINAHL WERE SEARCHED THROUGH JUNE 2018. RANDOMIZED CONTROLLED TRIALS WITH PATIENTS WITH MOOD AND ANXIETY DISORDERS WERE INCLUDED. MAIN OUTCOMES WERE CONTINUOUS MEASURES OF SEVERITY OF MOOD AND ANXIETY SYMPTOMS. COHEN'S D WAS CALCULATED AS A MEASURE OF EFFECT SIZE. META-ANALYSES USING A RANDOM EFFECTS MODEL WAS APPLIED TO ESTIMATE DIRECT COMPARISONS BETWEEN YOGA AND CONTROL CONDITIONS FOR DEPRESSION AND ANXIETY OUTCOMES. PUBLICATION BIAS WAS VISUALLY INSPECTED USING FUNNEL PLOTS. RESULTS: EIGHTEEN STUDIES WERE FOUND, FOURTEEN IN ACUTE PATIENTS AND FOUR IN CHRONIC PATIENTS. MOST STUDIES WERE OF LOW QUALITY. FOR DEPRESSION OUTCOMES, HATHA YOGA DID NOT SHOW A SIGNIFICANT EFFECT WHEN COMPARED TO TREATMENT AS USUAL, AN OVERALL EFFECT SIZE OF COHEN'S D -0.64 (95% CI = -1.41, 0.13) OR TO ALL ACTIVE CONTROL GROUPS, COHEN'S D -0.13 (95% CI = -0.49, 0.22). A SUB-ANALYSIS SHOWED THAT YOGA HAD A SIGNIFICANT EFFECT ON THE REDUCTION OF DEPRESSION COMPARED TO PSYCHOEDUCATION CONTROL GROUPS, COHEN'S D -0.52 (95% CI = -0.96, -0.08) BUT NOT TO OTHER ACTIVE CONTROL GROUPS, COHEN'S D 0.28 (95% CI = -0.07, 0.63) FOR STUDIES USING A FOLLOW-UP OF SIX MONTHS OR MORE, HATHA YOGA HAD NO EFFECT ON THE REDUCTION OF DEPRESSION COMPARED TO ACTIVE CONTROL GROUPS, COHEN'S D -0.14 (95% CI = -0.60, 0.33). REGARDING ANXIETY, HATHA YOGA HAD NO SIGNIFICANT EFFECT WHEN COMPARED TO ACTIVE CONTROL GROUPS, COHEN'S D -0.09 (95% CI = -0.47, 0.30). THE I2 AND Q-STATISTIC REVEALED HETEROGENEITY AMONGST COMPARISONS. QUALITATIVE ANALYSES SUGGEST SOME PROMISE OF HATHA YOGA FOR CHRONIC POPULATIONS. CONCLUSIONS: THE ABILITY TO DRAW FIRM CONCLUSIONS IS LIMITED BY THE NOTABLE HETEROGENEITY AND LOW QUALITY OF MOST OF THE INCLUDED STUDIES. WITH THIS CAVEAT IN MIND, THE RESULTS OF THE CURRENT META-ANALYSIS SUGGEST THAT HATHA YOGA DOES NOT HAVE EFFECTS ON ACUTE, CHRONIC AND/OR TREATMENT-RESISTANT MOOD AND ANXIETY DISORDERS COMPARED TO TREATMENT AS USUAL OR ACTIVE CONTROL GROUPS. HOWEVER, WHEN COMPARED TO PSYCHOEDUCATION, HATHA YOGA SHOWED MORE REDUCTIONS IN DEPRESSION. IT IS CLEAR THAT MORE HIGH-QUALITY STUDIES ARE NEEDED TO ADVANCE THE FIELD.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                           
17 2165  49 THE EFFECTS OF YOGA COMPARED TO ACTIVE AND INACTIVE CONTROLS ON PHYSICAL FUNCTION AND HEALTH RELATED QUALITY OF LIFE IN OLDER ADULTS- SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED CONTROLLED TRIALS. BACKGROUND: YOGA HAS BEEN RECOMMENDED AS A MUSCLE STRENGTHENING AND BALANCE ACTIVITY IN NATIONAL AND GLOBAL PHYSICAL ACTIVITY GUIDELINES. HOWEVER, THE EVIDENCE BASE ESTABLISHING THE EFFECTIVENESS OF YOGA IN IMPROVING PHYSICAL FUNCTION AND HEALTH RELATED QUALITY OF LIFE (HRQOL) IN AN OLDER ADULT POPULATION NOT RECRUITED ON THE BASIS OF ANY SPECIFIC DISEASE OR CONDITION, HAS NOT BEEN SYSTEMATICALLY REVIEWED. THE OBJECTIVE OF THIS STUDY WAS TO SYNTHESISE EXISTING EVIDENCE ON THE EFFECTS OF YOGA ON PHYSICAL FUNCTION AND HRQOL IN OLDER ADULTS NOT CHARACTERISED BY ANY SPECIFIC CLINICAL CONDITION. METHODS: THE FOLLOWING DATABASES WERE SYSTEMATICALLY SEARCHED IN SEPTEMBER 2017: MEDLINE, PSYCINFO, CINAHL PLUS, SCOPUS, WEB OF SCIENCE, COCHRANE LIBRARY, EMBASE, SPORTDISCUS, AMED AND PROQUEST DISSERTATIONS & THESES GLOBAL. STUDY INCLUSION CRITERIA: OLDER ADULT PARTICIPANTS WITH MEAN AGE OF 60 YEARS AND ABOVE, NOT RECRUITED ON THE BASIS OF ANY SPECIFIC DISEASE OR CONDITION; YOGA INTERVENTION COMPARED WITH INACTIVE CONTROLS (EXAMPLE: WAIT-LIST CONTROL, EDUCATION BOOKLETS) OR ACTIVE CONTROLS (EXAMPLE: WALKING, CHAIR AEROBICS); PHYSICAL FUNCTION AND HRQOL OUTCOMES; AND RANDOMISED/CLUSTER RANDOMISED CONTROLLED TRIALS PUBLISHED IN ENGLISH. A VOTE COUNTING ANALYSIS AND META-ANALYSIS WITH STANDARDISED EFFECT SIZES (HEDGES' G) COMPUTED USING RANDOM EFFECTS MODELS WERE CONDUCTED. RESULTS: A TOTAL OF 27 RECORDS FROM 22 RCTS WERE INCLUDED (17 RCTS ASSESSED PHYSICAL FUNCTION AND 20 ASSESSED HRQOL). THE META-ANALYSIS REVEALED SIGNIFICANT EFFECTS (5% LEVEL OF SIGNIFICANCE) FAVOURING THE YOGA GROUP FOR THE FOLLOWING PHYSICAL FUNCTION OUTCOMES COMPARED WITH INACTIVE CONTROLS: BALANCE (EFFECT SIZE (ES) = 0.7), LOWER BODY FLEXIBILITY (ES = 0.5), LOWER LIMB STRENGTH (ES = 0.45); COMPARED WITH ACTIVE CONTROLS: LOWER LIMB STRENGTH (ES = 0.49), LOWER BODY FLEXIBILITY (ES = 0.28). FOR HRQOL, SIGNIFICANT EFFECTS FAVOURING YOGA WERE FOUND COMPARED TO INACTIVE CONTROLS FOR: DEPRESSION (ES = 0.64), PERCEIVED MENTAL HEALTH (ES = 0.6), PERCEIVED PHYSICAL HEALTH (ES = 0.61), SLEEP QUALITY (ES = 0.65), AND VITALITY (ES = 0.31); COMPARED TO ACTIVE CONTROLS: DEPRESSION (ES = 0.54). CONCLUSION: THIS REVIEW IS THE FIRST TO COMPARE THE EFFECTS OF YOGA WITH ACTIVE AND INACTIVE CONTROLS IN OLDER ADULTS NOT CHARACTERISED BY A SPECIFIC CLINICAL CONDITION. RESULTS INDICATE THAT YOGA INTERVENTIONS IMPROVE MULTIPLE PHYSICAL FUNCTION AND HRQOL OUTCOMES IN THIS POPULATION COMPARED TO BOTH CONTROL CONDITIONS. THIS STUDY PROVIDES ROBUST EVIDENCE FOR PROMOTING YOGA IN PHYSICAL ACTIVITY GUIDELINES FOR OLDER ADULTS AS A MULTIMODAL ACTIVITY THAT IMPROVES ASPECTS OF FITNESS LIKE STRENGTH, BALANCE AND FLEXIBILITY, AS WELL AS MENTAL WELLBEING. TRIAL REGISTRATION: PROSPERO REGISTRATION NUMBER: CRD42016038052 .	2019	

18 2104  50 THE EFFECT OF YOGA ON HEALTH-RELATED FITNESS AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS: A SYSTEMATIC REVIEW AND META-ANALYSIS. BACKGROUND: THERE IS A NEED FOR A TYPE OF PHYSICAL ACTIVITY THAT COULD ADDRESS THE CHALLENGING CYCLE OF PHYSICAL INACTIVITY, IMPAIRED HEALTH-RELATED FITNESS, AND TYPE 2 DIABETES MELLITUS (T2DM) CONDITIONS. YOGA COULD BE ONE TYPE OF EXERCISE TO OVERCOME THE BARRIERS TO ADHERE TO REGULAR PHYSICAL ACTIVITY. THE CURRENT STUDY AIMED TO SYSTEMATICALLY REVIEW THE EFFECT OF YOGA ON HEALTH-RELATED FITNESS, INCLUDING CARDIORESPIRATORY FITNESS, MUSCLE STRENGTH, BODY COMPOSITION, BALANCE, AND FLEXIBILITY, AMONG PATIENTS WITH T2DM. METHODS: WE SYSTEMATICALLY SEARCHED FOUR DATABASES AND TWO REGISTRIES (PUBMED, SCOPUS, COCHRANE, EMBASE, WHO-ITCRP, AND CLINICALTRIALS.GOV) IN SEPTEMBER 2021, FOLLOWING A REGISTERED PROTOCOL ON PROSPERO (CRD42022276225). STUDY INCLUSION CRITERIA WERE T2DM PATIENTS WITH OR WITHOUT COMPLICATION, YOGA INTERVENTION AS A SINGLE COMPONENT OR AS A COMPLEMENT COMPARED TO OTHER KINDS OF EXERCISE OR AN INACTIVE CONTROL, HEALTH-RELATED FITNESS, AND A RANDOMIZED, CONTROLLED TRIAL OR QUASI-EXPERIMENTAL WITH CONTROL GROUP DESIGN. THE ROBINS-I TOOL AND ROB 2.0 TOOL WERE USED TO ASSESS THE RISK OF BIAS IN THE INCLUDED STUDIES. A VOTE-COUNTING ANALYSIS AND META-ANALYSIS COMPUTED USING RANDOM EFFECTS' MODELS WERE CONDUCTED. RESULTS: A TOTAL OF 10 RECORDS FROM 3 QUASI-EXPERIMENTAL AND 7 RANDOMIZED, CONTROLLED TRIALS WITH 815 PARTICIPANTS IN TOTAL WERE INCLUDED. THE META-ANALYSIS FAVORED YOGA GROUPS COMPARED TO INACTIVE CONTROLS IN IMPROVING MUSCLE STRENGTH BY 3.42 (95% CONFIDENCE INTERVAL 2.42 TO 4.43), REPETITIONS OF CHAIR STAND TEST, AND IMPROVING CARDIORESPIRATORY FITNESS BY 6.6% (95% CONFIDENCE INTERVAL 0.4 TO 12.8) IMPROVEMENT OF BASELINE FORCED VITAL CAPACITY. THE QUALITY OF EVIDENCE FOR BOTH OUTCOMES WAS LOW. CONCLUSION: LOW-QUALITY EVIDENCE FAVORED YOGA IN IMPROVING HEALTH-RELATED FITNESS, PARTICULARLY MUSCLE STRENGTH AND CARDIORESPIRATORY FITNESS, AMONG PATIENTS WITH T2DM. FUNDING: ALL AUTHORS IN THIS SYSTEMATIC REVIEW RECEIVED NO SPECIFIC GRANT FROM ANY FUNDING AGENCY IN THE PUBLIC, COMMERCIAL, OR NOT-FOR-PROFIT SECTORS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
19 2612  38 YOGA FOR RHEUMATIC DISEASES: A SYSTEMATIC REVIEW. OBJECTIVE: TO EVALUATE THE QUALITY OF EVIDENCE AND THE STRENGTH OF RECOMMENDATION FOR YOGA AS AN ANCILLARY INTERVENTION IN RHEUMATIC DISEASES. METHODS: MEDLINE/PUBMED, SCOPUS, THE COCHRANE LIBRARY AND INDMED WERE SEARCHED THROUGH FEBRUARY 2013. RANDOMIZED CONTROLLED TRIALS (RCTS) COMPARING YOGA WITH CONTROL INTERVENTIONS IN PATIENTS WITH RHEUMATIC DISEASES WERE INCLUDED. TWO AUTHORS INDEPENDENTLY ASSESSED THE RISK OF BIAS USING THE COCHRANE BACK REVIEW GROUP RISK OF BIAS TOOL. THE QUALITY OF EVIDENCE AND THE STRENGTH OF THE RECOMMENDATION FOR OR AGAINST YOGA WERE GRADED ACCORDING TO THE GRADE RECOMMENDATIONS. RESULTS: EIGHT RCTS WITH A TOTAL OF 559 SUBJECTS WERE INCLUDED; TWO RCTS HAD A LOW RISK OF BIAS. IN TWO RCTS ON FM SYNDROME, THERE WAS VERY LOW EVIDENCE FOR EFFECTS ON PAIN AND LOW EVIDENCE FOR EFFECTS ON DISABILITY. IN THREE RCTS ON OA, THERE WAS VERY LOW EVIDENCE FOR EFFECTS ON PAIN AND DISABILITY. BASED ON TWO RCTS, VERY LOW EVIDENCE WAS FOUND FOR EFFECTS ON PAIN IN RA. NO EVIDENCE FOR EFFECTS ON PAIN WAS FOUND IN ONE RCT ON CTS. NO RCT EXPLICITLY REPORTED SAFETY DATA. CONCLUSION: BASED ON THE RESULTS OF THIS REVIEW, ONLY WEAK RECOMMENDATIONS CAN BE MADE FOR THE ANCILLARY USE OF YOGA IN THE MANAGEMENT OF FM SYNDROME, OA AND RA AT THIS POINT.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
20 2098  39 THE EFFECT OF YOGA INTERVENTIONS ON CANCER-RELATED FATIGUE AND QUALITY OF LIFE FOR WOMEN WITH BREAST CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. BACKGROUND: WOMEN WITH BREAST CANCER (BC) ARE LIVING LONGER WITH DEBILITATING SIDE EFFECTS SUCH AS CANCER-RELATED FATIGUE (CRF) THAT AFFECT OVERALL WELL-BEING. YOGA PROMOTES HEALTH, WELL-BEING AND MAY BE BENEFICIAL IN REDUCING CRF. ALTHOUGH THERE HAVE BEEN PREVIOUS SYSTEMATIC REVIEWS AND META-ANALYSES, THE EFFECTS OF YOGA ON CRF AND QUALITY OF LIFE (QOL) REMAIN UNCLEAR, PARTICULARLY IN COMPARISON WITH OTHER TYPES OF PHYSICAL ACTIVITY (PA). OUR OBJECTIVE IS TO CARRY OUT A SYSTEMATIC REVIEW AND META-ANALYSIS OF THE EFFECTS OF YOGA ON CRF AND QOL IN WOMEN WITH BC. METHODS: ELECTRONIC DATABASES WERE SEARCHED (MEDLINE, EMBASE CLASSIC+EMBASE AND EMB REVIEWS, COCHRANE CENTRAL CT) FROM INCEPTION TO MAY 2018. RANDOMIZED CONTROLLED TRIALS WERE INCLUDED IF THEY WERE FULL TEXT, IN ENGLISH, INCLUDED A YOGA INTERVENTION, A COMPARATOR (INCLUDING NON-PA USUAL CARE OR ALTERNATE PA INTERVENTION), AND REPORTED ON CRF OR QOL. EFFECTS OF YOGA WERE POOLED USING STANDARDIZED MEAN DIFFERENCE (SMD) VIA A RANDOM EFFECTS MODEL. RESULTS: OF THE 2468 RECORDS RETRIEVED, 24 TRIALS WERE INCLUDED; 18 STUDIES COMPARED YOGA TO A NON-PA COMPARATOR AND 6 TO A PA COMPARATOR. YOGA DEMONSTRATED STATISTICALLY SIGNIFICANT IMPROVEMENTS IN CRF OVER NON-PA (SMD -0.30 [-0.51; -0.08]) BUT NOT PA (SMD -0.17 [-0.50; 0.17]) COMPARATORS. ADDITIONALLY, YOGA DEMONSTRATED STATISTICALLY SIGNIFICANT IMPROVEMENTS IN QOL OVER NON-PA (SMD -0.27 [-0.46; -0.07]) BUT NOT PA (SMD 0.04 [-0.22; +0.31]) COMPARATORS. DISCUSSION: THIS META-ANALYSIS FOUND THAT YOGA PROVIDES SMALL TO MEDIUM IMPROVEMENTS IN CRF AND QOL COMPARED TO NON-PA, BUT NOT IN COMPARISON TO OTHER PA INTERVENTIONS.	2020