1  877 106 EFFECT OF YOGA THERAPY ON SYMPTOMS OF ANXIETY IN CANCER PATIENTS. BACKGROUND: MANY CANCER PATIENTS SUFFER FROM SYMPTOMS OF ANXIETY, DEPRESSION, AND FATIGUE. SUPPORTIVE TREATMENTS ARE INCREASINGLY USED TO ALLEVIATE DISTRESS IN CANCER. IN THIS STUDY, THE EFFECTS OF YOGA ON THESE SYMPTOMS ARE EXAMINED. METHODS: WE PERFORMED A RANDOMIZED CONTROLLED STUDY ON CANCER PATIENTS WITH MIXED DIAGNOSES COMPARING YOGA THERAPY WITH A WAITING LIST CONTROL GROUP. WE MEASURED ANXIETY SYMPTOMS WITH THE GENERAL ANXIETY DISORDER (GAD-7) SCALE, DEPRESSIVE SYMPTOMS WITH THE PATIENT HEALTH QUESTIONNAIRE-2 (PHQ-2), AND FATIGUE WITH THE EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER FATIGUE SCALE (EORTC QLQ-FA13). YOGA THERAPY WAS CARRIED OUT IN WEEKLY SESSIONS OF 60 MIN EACH FOR 8 WEEKS. THE PROGRAM PROVIDED RESTRAINED BODY AND BREATHING EXERCISES AS WELL AS MEDITATION. THE CONTROL GROUP DID NOT RECEIVE ANY YOGA THERAPY WHILE ON THE WAITING LIST. RESULTS: A TOTAL OF 70 SUBJECTS PARTICIPATED IN THE STUDY. ANXIETY WAS SIGNIFICANTLY REDUCED BY THE YOGA THERAPY IN THE INTERVENTION GROUP COMPARED TO THE CONTROL GROUP (P = 0.005). HOWEVER, YOGA THERAPY DID NOT SHOW ANY SIGNIFICANT EFFECTS ON DEPRESSION (P = 0.21) AND FATIGUE (P = 0.11) COMPARED TO THE CONTROL GROUP. CONCLUSION: YOGA THERAPY MAY BE USED TO ALLEVIATE ANXIETY SYMPTOMS IN CANCER PATIENTS AND SHOULD BE THE SUBJECT OF FURTHER RESEARCH.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
2 1556  69 LONG-TERM CHANGES OF SYMPTOMS OF ANXIETY, DEPRESSION, AND FATIGUE IN CANCER PATIENTS 6 MONTHS AFTER THE END OF YOGA THERAPY. BACKGROUND: SYMPTOMS OF ANXIETY, DEPRESSION, AND CANCER-RELATED FATIGUE ARE COMMONLY ASSOCIATED WITH CANCER. CANCER PATIENTS INCREASINGLY USE COMPLEMENTARY AND ALTERNATIVE TREATMENTS, SUCH AS YOGA, TO COPE WITH PSYCHOLOGICAL AND PHYSICAL IMPAIRMENTS. IN THE PRESENT ARTICLE, LONG-TERM CHANGES OF ANXIETY, DEPRESSION, AND FATIGUE IN CANCER ARE EXAMINED 6 MONTHS AFTER A YOGA INTERVENTION. METHOD: WE USED AN OBSERVATIONAL DESIGN BASED ON A RANDOMIZED CONTROLLED STUDY IN CANCER PATIENTS WITH MIXED DIAGNOSES TO EVALUATE LONG-TERM CHANGES OF SYMPTOMS OF ANXIETY, DEPRESSION, AND FATIGUE 6 MONTHS AFTER THE END OF YOGA THERAPY. WE MEASURED ANXIETY SYMPTOMS WITH THE GENERALIZED ANXIETY DISORDER SCALE (GAD-7), DEPRESSIVE SYMPTOMS WITH THE PATIENT HEALTH QUESTIONNAIRE-2 (PHQ-2), AND FATIGUE WITH THE EUROPEAN ORGANIZATION FOR RESEARCH AND TREATMENT OF CANCER QUALITY OF LIFE QUESTIONNAIRE-FATIGUE SCALE (EORTC QLQ-FA13). YOGA THERAPY WAS PROVIDED IN YOGA CLASSES OF 60 MINUTES EACH ONCE A WEEK FOR 8 WEEKS IN TOTAL. THE EXERCISES PROVIDED CONTAINED BOTH BODY AND BREATHING ACTIVITIES AS WELL AS MEDITATION. RESULTS: A TOTAL OF 58 PATIENTS PARTICIPATED IN THE STUDY. SIX MONTHS AFTER THE END OF YOGA THERAPY, SYMPTOMS OF ANXIETY, DEPRESSION, AND FATIGUE WERE SIGNIFICANTLY REDUCED COMPARED WITH BASELINE. HOWEVER, SYMPTOMS OF ANXIETY AND FATIGUE SLIGHTLY INCREASED DURING THE FOLLOW-UP PERIOD, WHEREAS SYMPTOMS OF DEPRESSION REMAINED STABLE. CONCLUSION: OUR RESULTS ARE PROMISING AND SUPPORT THE INTEGRATION OF YOGA INTERVENTIONS IN SUPPORTIVE CANCER TREATMENT CONCEPTS BUT SHOULD BE CONFIRMED BY RANDOMIZED CONTROLLED TRIALS. LONG-TERM EFFECTS OF YOGA THERAPY ON CANCER PATIENTS SHOULD BE THE SUBJECT OF FURTHER RESEARCH.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
3  428  32 CAN YOGA HAVE ANY EFFECT ON SHOULDER AND ARM PAIN AND QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER? A RANDOMIZED, CONTROLLED, SINGLE-BLIND TRIAL. OBJECTIVE: TO EXAMINE THE EFFECTS OF YOGA ON SHOULDER AND ARM PAIN, QUALITY OF LIFE (QOL), DEPRESSION, AND PHYSICAL PERFORMANCE IN PATIENTS WITH BREAST CANCER. METHODS: THIS PROSPECTIVE, RANDOMIZED STUDY INCLUDED 42 PATIENTS. THE PATIENTS IN GROUP 1 UNDERWENT A 10-WEEK HATHA YOGA EXERCISE PROGRAM. THE PATIENTS IN GROUP 2 WERE INCLUDED IN A 10-WEEK FOLLOW-UP PROGRAM. OUR PRIMARY ENDPOINT WAS ARM AND SHOULDER PAIN INTENSITY. RESULTS: THE GROUP RECEIVING YOGA SHOWED A SIGNIFICANT IMPROVEMENT IN THEIR PAIN SEVERITY FROM BASELINE TO POST-TREATMENT, AND THESE BENEFITS WERE MAINTAINED AT 2.5 MONTHS POST-TREATMENT. WHEN COMPARED TO THE CONTROL GROUP, THERE WERE NO STATISTICALLY SIGNIFICANT DIFFERENCES BETWEEN THE 2 GROUPS WITH RESPECT TO THE PARAMETERS ASSESSED AT THE END OF WEEK 10. CONCLUSION: YOGA WAS AN EFFECTIVE AND SAFE EXERCISE FOR ALLEVIATING SHOULDER AND ARM PAIN, WHICH IS A COMPLICATION WITH A HIGH PREVALENCE IN PATIENTS WITH BREAST CANCER.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
4 2096  47 THE EFFECT OF YOGA EXERCISE ON IMPROVING DEPRESSION, ANXIETY, AND FATIGUE IN WOMEN WITH BREAST CANCER: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: DEPRESSION, ANXIETY, AND FATIGUE ARE AMONG THE MOST SIGNIFICANT PROBLEMS THAT INFLUENCE THE QUALITY OF LIFE OF PATIENTS WITH BREAST CANCER WHO RECEIVE ADJUVANT CHEMOTHERAPY. ALTHOUGH EVIDENCE HAS SHOWN YOGA TO DECREASE ANXIETY, DEPRESSION, AND FATIGUE IN PATIENTS WITH CANCER, FEW STUDIES ON THE EFFECTS OF YOGA HAVE TARGETED PATIENTS WITH BREAST CANCER. YOGA INTERVENTIONS SHOULD BE TESTED TO PROMOTE THE PSYCHOLOGICAL AND PHYSICAL HEALTH OF WOMEN WITH BREAST CANCER. PURPOSE: THIS STUDY EXAMINES THE EFFECTIVENESS OF AN 8-WEEK YOGA EXERCISE PROGRAM IN PROMOTING THE PSYCHOLOGICAL AND PHYSICAL HEALTH OF WOMEN WITH BREAST CANCER UNDERGOING ADJUVANT CHEMOTHERAPY IN TERMS OF DEPRESSION, ANXIETY, AND FATIGUE. METHODS: A SAMPLE OF 60 WOMEN WITH NONMETASTATIC BREAST CANCER WAS RECRUITED. PARTICIPANTS WERE RANDOMLY ASSIGNED INTO EITHER THE EXPERIMENTAL GROUP (N = 30) OR THE CONTROL GROUP (N = 30). A 60-MINUTE, TWICE-PER-WEEK YOGA EXERCISE WAS IMPLEMENTED FOR 8 WEEKS AS THE INTERVENTION FOR THE PARTICIPANTS IN THE EXPERIMENTAL GROUP. THE CONTROL GROUP RECEIVED STANDARD CARE ONLY. RESULTS: ANALYSIS USING THE JOHNSON-NEYMAN PROCEDURE FOUND THAT THE YOGA EXERCISE REDUCED OVERALL FATIGUE AND THE INTERFERENCE OF FATIGUE IN EVERYDAY LIFE FOR THE EXPERIMENTAL GROUP PARTICIPANTS. SIGNIFICANT REDUCTIONS WERE OBTAINED AFTER 4 WEEKS OF INTERVENTION PARTICIPATION FOR THOSE EXPERIMENTAL GROUP PATIENTS WITH RELATIVELY LOW STARTING BASELINE VALUES (BASELINE ITEM MEAN VALUE < 3.31 AND 3.22, RESPECTIVELY) AND AFTER 8 WEEKS FOR MOST PATIENTS (APPROXIMATELY 75%) WITH MODERATE STARTING BASELINE VALUES (BASELINE ITEM MEAN VALUE < 7.30 AND 5.34, RESPECTIVELY). THE 8-WEEK INTERVENTION DID NOT SIGNIFICANTLY IMPROVE THE LEVELS OF DEPRESSION (F = 1.29, P > .05) OR ANXIETY (F = 2.7, P > .05). CONCLUSIONS/IMPLICATIONS FOR PRACTICE: THE 8-WEEK YOGA EXERCISE PROGRAM DEVELOPED IN THIS STUDY EFFECTIVELY REDUCED FATIGUE IN PATIENTS WITH BREAST CANCER BUT DID NOT REDUCE DEPRESSION OR ANXIETY. ONCOLOGY NURSES SHOULD STRENGTHEN THEIR CLINICAL HEALTH EDUCATION AND APPLY YOGA TO REDUCE THE FATIGUE EXPERIENCED BY PATIENTS WITH BREAST CANCER WHO UNDERGO ADJUVANT CHEMOTHERAPY.	2014	

5 2508  49 YOGA BREATHING FOR CANCER CHEMOTHERAPY-ASSOCIATED SYMPTOMS AND QUALITY OF LIFE: RESULTS OF A PILOT RANDOMIZED CONTROLLED TRIAL. BACKGROUND: MANY DEBILITATING SYMPTOMS ARISE FROM CANCER AND ITS TREATMENT THAT ARE OFTEN UNRELIEVED BY ESTABLISHED METHODS. PRANAYAMA, A SERIES OF YOGIC BREATHING TECHNIQUES, MAY IMPROVE CANCER-RELATED SYMPTOMS AND QUALITY OF LIFE, BUT IT HAS NOT BEEN STUDIED FOR THIS PURPOSE. OBJECTIVES: A PILOT STUDY WAS PERFORMED TO EVALUATE FEASIBILITY AND TO TEST THE EFFECTS OF PRANAYAMA ON CANCER-ASSOCIATED SYMPTOMS AND QUALITY OF LIFE. DESIGN: THIS WAS A RANDOMIZED CONTROLLED CLINICAL TRIAL COMPARING PRANAYAMA TO USUAL CARE. SETTING: THE STUDY WAS CONDUCTED AT A UNIVERSITY MEDICAL CENTER. SUBJECTS: PATIENTS RECEIVING CANCER CHEMOTHERAPY WERE RANDOMIZED TO RECEIVE PRANAYAMA IMMEDIATELY OR AFTER A WAITING PERIOD (CONTROL GROUP). INTERVENTIONS: THE PRANAYAMA INTERVENTION CONSISTED OF FOUR BREATHING TECHNIQUES TAUGHT IN WEEKLY CLASSES AND PRACTICED AT HOME. THE TREATMENT GROUP RECEIVED PRANAYAMA DURING TWO CONSECUTIVE CYCLES OF CHEMOTHERAPY. THE CONTROL GROUP RECEIVED USUAL CARE DURING THEIR FIRST CYCLE, AND RECEIVED PRANAYAMA DURING THEIR SECOND CYCLE OF CHEMOTHERAPY. OUTCOME MEASURES: FEASIBILITY, CANCER-ASSOCIATED SYMPTOMS (FATIGUE, SLEEP DISTURBANCE, ANXIETY, DEPRESSION, STRESS), AND QUALITY OF LIFE WERE THE OUTCOMES. RESULTS: CLASS ATTENDANCE WAS NEARLY 100% IN BOTH GROUPS. SIXTEEN (16) PARTICIPANTS WERE INCLUDED IN THE FINAL INTENT-TO-TREAT ANALYSES. THE REPEATED-MEASURES ANALYSES DEMONSTRATED THAT ANY INCREASE IN PRANAYAMA DOSE, WITH DOSE MEASURED IN THE NUMBER OF HOURS PRACTICED IN CLASS OR AT HOME, RESULTED IN IMPROVED SYMPTOM AND QUALITY-OF-LIFE SCORES. SEVERAL OF THESE ASSOCIATIONS--SLEEP DISTURBANCE (P=0.04), ANXIETY (P=0.04), AND MENTAL QUALITY OF LIFE (P=0.05)--REACHED OR APPROACHED STATISTICAL SIGNIFICANCE. CONCLUSIONS: YOGA BREATHING WAS A FEASIBLE INTERVENTION AMONG PATIENTS WITH CANCER RECEIVING CHEMOTHERAPY. PRANAYAMA MAY IMPROVE SLEEP DISTURBANCE, ANXIETY, AND MENTAL QUALITY OF LIFE. A DOSE-RESPONSE RELATIONSHIP WAS FOUND BETWEEN PRANAYAMA USE AND IMPROVEMENTS IN CHEMOTHERAPY-ASSOCIATED SYMPTOMS AND QUALITY OF LIFE. THESE FINDINGS NEED TO BE CONFIRMED IN A LARGER STUDY.	2012	
                                                                 
6 2080  39 THE EFFECT OF GROUP MINDFULNESS - BASED STRESS REDUCTION PROGRAM AND CONSCIOUS YOGA ON THE FATIGUE SEVERITY AND GLOBAL AND SPECIFIC LIFE QUALITY IN WOMEN WITH BREAST CANCER. BACKGROUND: CANCER IS NOT MERELY AN EVENT WITH A CERTAIN END, BUT IT IS A PERMANENT AND VAGUE SITUATION THAT IS DETERMINED BY DELAYED EFFECTS DUE TO THE DISEASE, ITS TREATMENT AND ITS RELATED PSYCHOLOGICAL ISSUES. THE AIM OF THIS STUDY WAS TO EXAMINE THE EFFECTIVENESS OF THE MINDFULNESS-BASED STRESS REDUCTION PROGRAM AND CONSCIOUS YOGA ON THE MENTAL FATIGUE SEVERITY AND LIFE QUALITY OF WOMEN WITH BREAST CANCER. METHODS: THIS WAS A QUASI-EXPERIMENTAL STUDY WITH A PRE-TEST, POST-TEST AND CONTROL GROUP. IN THIS STUDY, 24 PATIENTS WITH THE DIAGNOSIS OF BREAST CANCER WERE SELECTED AMONG THE PATIENTS WHO REFERRED TO THE DIVISION OF ONCOLOGY AND RADIOTHERAPY OF IMAM HOSSEIN HOSPITAL IN TEHRAN USING AVAILABLE SAMPLING METHOD, AND WERE RANDOMLY ASSIGNED INTO THE EXPERIMENTAL AND CONTROL GROUPS. ALL THE PARTICIPANTS COMPLETED THE FATIGUE SEVERITY SCALE, GLOBAL LIFE QUALITY OF CANCER PATIENT AND SPECIFIC LIFE QUALITY OF CANCER PATIENT QUESTIONNAIRES. DATA WERE ANALYZED BY MULTIVARIATE REPEATED MEASUREMENT VARIANCE ANALYSIS MODEL. RESULTS: FINDINGS REVEALED THAT THE MINDFULNESS-BASED STRESS REDUCTION TREATMENT SIGNIFICANTLY IMPROVED THE OVERALL QUALITY OF LIFE, ROLE, COGNITIVE, EMOTION, SOCIAL FUNCTIONS AND PAIN AND FATIGUE SYMPTOMS IN GLOBAL LIFE QUALITY IN THE EXPERIMENTAL GROUP. IT ALSO SIGNIFICANTLY IMPROVED THE BODY IMAGE, FUTURE FUNCTIONS AND THERAPY SIDE EFFECTS IN SPECIFIC LIFE QUALITY OF THE EXPERIMENTAL GROUP COMPARED TO THE CONTROL GROUP. IN ADDITION, FATIGUE SEVERITY CAUSED BY CANCER WAS REDUCED SIGNIFICANTLY. CONCLUSION: THE RESULTS SHOWED THAT THE MINDFULNESS - BASED STRESS REDUCTION TREATMENT CAN BE EFFECTIVE IN IMPROVING GLOBAL AND SPECIFIC LIFE QUALITY AND FATIGUE SEVERITY IN WOMEN WITH BREAST CANCER.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                             
7 1076  40 EFFECTS OF YOGA ON PHYSIOLOGICAL INDICES, ANXIETY AND SOCIAL FUNCTIONING IN MULTIPLE SCLEROSIS PATIENTS: A RANDOMIZED TRIAL. INTRODUCTION: MULTIPLE SCLEROSIS (MS) AS A CHRONIC DISEASE COULD AFFECT PATIENTS' VARIOUS DOMAINS OF LIFE. AIM: THIS STUDY WAS CONDUCTED TO STUDY THE EFFECT OF YOGA ON THE PHYSIOLOGICAL INDICES, ANXIETY AND SOCIAL FUNCTIONING OF PATIENTS WITH MS IN SOUTHWEST, IRAN. MATERIALS AND METHODS: IN THIS CLINICAL TRIAL STUDY, 60 MS PATIENTS WERE ENROLLED ACCORDING TO INCLUSION CRITERIA AND RANDOMLY ASSIGNED TO TWO GROUPS OF 30 EACH. PRIOR TO AND AFTER INTERVENTION, THE PATIENTS' VITAL SIGNS WERE MEASURED. FOR CASE GROUP YOGA EXERCISES WERE PERFORMED THREE SESSIONS A WEEK FOR 12 WEEKS WHILE CONTROL GROUP PERFORMED NO EXERCISE. THE DATA WERE GATHERED BY QUESTIONNAIRE AND ANALYSED BY DESCRIPTIVE AND ANALYTICAL STATISTICS IN SPSS. RESULTS: PRIOR TO INTERVENTION, THERE WAS NO SIGNIFICANT DIFFERENCE IN FATIGUE SEVERITY AND PAIN BETWEEN THE TWO GROUPS BUT THE MEAN FATIGUE SEVERITY AND PAIN IN CASE GROUP DECREASED COMPARED TO THE CONTROL GROUP AFTER THE INTERVENTION. PRIOR TO INTERVENTION, THERE WAS NO SIGNIFICANT DIFFERENCE IN MEAN PHYSIOLOGICAL INDICES BETWEEN THE TWO GROUPS BUT THE MEAN PHYSIOLOGICAL INDICES IN CASE GROUP DECREASED SIGNIFICANTLY AFTER THE INTERVENTION (P<0.05). CONCLUSION: YOGA IS LIKELY TO INCREASE SELF-EFFICACY OF MS PATIENTS THROUGH ENHANCING PHYSICAL ACTIVITY, INCREASING THE STRENGTH OF LOWER LIMBS AND BALANCE, AND DECREASING FATIGUE AND PAIN, AND FINALLY TO PROMOTE SOCIAL FUNCTIONING AND TO RELIEVE STRESS AND ANXIETY IN THESE PATIENTS.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
8  159  33 A RANDOMISED COMPARATIVE TRIAL OF YOGA AND RELAXATION TO REDUCE STRESS AND ANXIETY. OBJECTIVE: TO COMPARE YOGA AND RELAXATION AS TREATMENT MODALITIES AT 10 AND 16 WEEKS FROM STUDY BASELINE TO DETERMINE IF EITHER OF MODALITY REDUCES SUBJECT STRESS, ANXIETY, BLOOD PRESSURE AND IMPROVE QUALITY OF LIFE. DESIGN: A RANDOMISED COMPARATIVE TRIAL WAS UNDERTAKEN COMPARING YOGA WITH RELAXATION. PARTICIPANTS: ONE HUNDRED AND THIRTY-ONE SUBJECTS WITH MILD TO MODERATE LEVELS OF STRESS WERE RECRUITED FROM THE COMMUNITY IN SOUTH AUSTRALIA. INTERVENTIONS: TEN WEEKLY 1- H SESSIONS OF RELAXATION OR HATHA YOGA. MAIN OUTCOME MEASURES: CHANGES IN THE STATE TRAIT PERSONALITY INVENTORY SUB-SCALE ANXIETY, GENERAL HEALTH QUESTIONNAIRE AND THE SHORT FORM-36. RESULTS: FOLLOWING THE 10 WEEK INTERVENTION STRESS, ANXIETY AND QUALITY OF LIFE SCORES IMPROVED OVER TIME. YOGA WAS FOUND TO BE AS EFFECTIVE AS RELAXATION IN REDUCING STRESS, ANXIETY AND IMPROVING HEALTH STATUS ON SEVEN DOMAINS OF THE SF-36. YOGA WAS MORE EFFECTIVE THAN RELAXATION IN IMPROVING MENTAL HEALTH. AT THE END OF THE 6 WEEK FOLLOW-UP PERIOD THERE WERE NO DIFFERENCES BETWEEN GROUPS IN LEVELS OF STRESS, ANXIETY AND ON FIVE DOMAINS OF THE SF-36. VITALITY, SOCIAL FUNCTION AND MENTAL HEALTH SCORES ON THE SF-36 WERE HIGHER IN THE RELAXATION GROUP DURING THE FOLLOW-UP PERIOD. CONCLUSION: YOGA APPEARS TO PROVIDE A COMPARABLE IMPROVEMENT IN STRESS, ANXIETY AND HEALTH STATUS COMPARED TO RELAXATION.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
9 1075  43 EFFECTS OF YOGA ON PHASE ANGLE AND QUALITY OF LIFE IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, SINGLE-BLIND, CONTROLLED TRIAL. INTRODUCTION: PHASE ANGLE (PA), A PARAMETER THAT IS OBTAINED FROM BODY COMPOSITION ANALYSIS, IS AN INDICATOR OF CELLULAR HEALTH STATUS. A LOWER PA IN CANCER PATIENTS CAN LEAD TO A DECREASE IN FUNCTIONAL STATUS AND QUALITY OF LIFE (QOL) AND INCREASED MORTALITY. STUDIES HAVE SHOWN THAT PHYSICAL ACTIVITY INCREASES PA. IN THIS STUDY, WE AIMED TO EXAMINE THE EFFECTS OF HATHA YOGA ON PA, BODY COMPOSITION, AND QOL IN PATIENTS WITH BREAST CANCER. METHODS: THIRTY-ONE PATIENTS WERE RANDOMIZED INTO THE YOGA (GROUP 1, N = 15) AND THE CONTROL GROUP (GROUP 2, N = 16). HATHA YOGA WAS PRACTICED TWICE A WEEK FOR 10 WEEKS IN THE INTERVENTION GROUP. THE PA OF THE PATIENTS WAS ASSESSED USING A BODY ANALYSIS INSTRUMENT, AND QOL WAS EVALUATED WITH AN EORTC QLQ QUESTIONNAIRE BOTH BEFORE TREATMENT AND AT WEEK 10. RESULTS: GROUP 1 HAD SIGNIFICANT IMPROVEMENTS IN THE POSTTREATMENT EORTC QLQ FUNCTIONAL AND GLOBAL SCORES (P < 0.05). IN GROUP 2, A SIGNIFICANT IMPROVEMENT WAS OBSERVED IN THE EORTC QLQ SYMPTOM SUBSCALE (P = 0.035). PA VALUES DID NOT SHOW ANY IMPROVEMENTS IN BOTH GROUPS (P > 0.05). COMPARISON OF THE 2 GROUPS REVEALED NO DIFFERENCES. CONCLUSION: YOGA MAY HAVE BENEFICIAL EFFECTS ON QOL IN PATIENTS WITH BREAST CANCER BUT DOES NOT HAVE A SIGNIFICANT EFFECT ON PA. THERE IS A NEED FOR FURTHER STUDIES TO MAKE A DEFINITIVE STATEMENT.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
10 2235  34 THE IMPACT OF YOGA UPON FEMALE PATIENTS SUFFERING FROM HYPOTHYROIDISM. OBJECTIVE: TO STUDY THE EFFECT OF YOGA ON THE QUALITY OF LIFE OF FEMALE HYPOTHYROID PATIENTS. DESIGN: THE WHO QUALITY OF LIFE SCALE(22) WAS USED TO ASSESS THE QUALITY OF LIFE OF 20 FEMALE HYPOTHYROID PATIENTS. SUBJECTS ATTENDED ONE HOUR YOGA SESSIONS DAILY FOR A PERIOD OF ONE MONTH. A PRETEST-POST-TEST RESEARCH DESIGN WAS USED FOR DATA ANALYSIS. RESULTS: PATIENTS' QUALITY OF LIFE SCORES FOLLOWING THE YOGA PROGRAM WERE GREATER THAN SCORES OBTAINED PRIOR TO UNDERTAKING YOGA (P < 0.01). PATIENTS ALSO REPORTED SIGNIFICANT IMPROVEMENT IN THEIR PERCEPTION OF THE OVERALL QUALITY OF LIFE AND OF THEIR HEALTH POST YOGA INTERVENTION. CONCLUSIONS: IT CAN BE CONCLUDED THAT YOGA IS VALUABLE IN HELPING THE HYPOTHYROID PATIENTS TO MANAGE THEIR DISEASE-RELATED SYMPTOMS. YOGA MAY BE CONSIDERED AS SUPPORTIVE OR COMPLEMENTARY THERAPY IN CONJUNCTION WITH MEDICAL THERAPY FOR THE TREATMENT OF HYPOTHYROID DISORDER.	2011	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
11 2119  36 THE EFFECT OF YOGA THERAPY ON SELECTED PSYCHOLOGICAL VARIABLES AMONG MALE PATIENTS WITH INSOMNIA. BACKGROUND: AN ESTIMATED 30-50% OF THE GENERAL POPULATION IS AFFECTED BY INSOMNIA AND 10% HAVE CHRONIC INSOMNIA. YOGA THERAPY IS BENEFICIAL IN SUCH DISORDERS AND IT HAS FEWER SIDE EFFECTS. AIM: THE AIM OF THIS STUDY WAS TO FIND OUT THE EFFECT OF YOGA THERAPY ON SELECTED PSYCHOLOGICAL VARIABLES AMONG MEN WITH INSOMNIA. METHODS: FORTY MALES WITH INSOMNIA WERE DIVIDED RANDOMLY INTO 2 GROUPS (THE EXPERIMENTAL AND THE CONTROL GROUPS). THE EXPERIMENTAL GROUP RECEIVED EIGHT WEEKS OF YOGA THERAPY, WHILE THE CONTROL GROUP DID NOT RECEIVE ANY THERAPY. THE PRE AND POST TREATMENT STRESS AND THE SELF CONFIDENCE SCORES WERE TAKEN. RESULTS: THERE WAS A SIGNIFICANT IMPROVEMENT IN THE STRESS SCORES AND THE SELF CONFIDENCE SCORES IN THE EXPERIMENTAL GROUP. THERE WERE NEITHER ANY SIDE EFFECTS NOR ANY DROP OUTS. CONCLUSION: WE CONCLUDE THAT YOGA IS AN EFFECTIVE TREATMENT OPTION FOR THE PATIENTS WITH INSOMNIA. THERE ARE NO MAJOR SIDE EFFECTS.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
12 2156  37 THE EFFECTS OF THE BALI YOGA PROGRAM FOR BREAST CANCER PATIENTS ON CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING: RESULTS OF A PARTIALLY RANDOMIZED AND BLINDED CONTROLLED TRIAL. COMPLEMENTARY AND ALTERNATIVE MEDICINE HAS BEEN SHOWN TO BE BENEFICIAL IN REDUCING CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING. HOWEVER, CONCLUSIVE RESULTS ARE LACKING IN ORDER TO CONFIRM ITS USEFULNESS. THE PURPOSE OF THIS STUDY WAS TO DETERMINE WHETHER A STANDARDIZED YOGA INTERVENTION COULD REDUCE THESE ADVERSE SYMPTOMS. THIS WAS A PARTIALLY RANDOMIZED AND BLINDED CONTROLLED TRIAL COMPARING A STANDARDIZED YOGA INTERVENTION WITH STANDARD CARE. ELIGIBLE PATIENTS WERE ADULTS DIAGNOSED WITH STAGES I TO III BREAST CANCER RECEIVING CHEMOTHERAPY. PATIENTS RANDOMIZED TO THE EXPERIMENTAL GROUP PARTICIPATED IN AN 8-WEEK YOGA PROGRAM. THERE WAS NO SIGNIFICANT DIFFERENCE BETWEEN THE EXPERIMENTAL AND CONTROL GROUPS ON CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING AFTER 8 WEEKS. RESULTS SUGGEST THE YOGA PROGRAM IS NOT BENEFICIAL IN MANAGING THESE ADVERSE SYMPTOMS. HOWEVER, CONSIDERING PRELIMINARY EVIDENCE SUGGESTING YOGA'S BENEFICIAL IMPACT IN CANCER SYMPTOM MANAGEMENT, METHODOLOGICAL LIMITATIONS SHOULD BE EXPLORED AND ADDITIONAL STUDIES SHOULD BE CONDUCTED.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
13 2883  30 YOGA: A TOOL FOR IMPROVING THE QUALITY OF LIFE IN CHRONIC PANCREATITIS. AIM: TO DETERMINE THE EFFECTIVENESS OF YOGA ON IMPROVING THE QUALITY OF LIFE IN PATIENTS OF CHRONIC PANCREATITIS. METHODS: THE PATIENTS WERE RANDOMIZED TO TWO GROUPS. THE CONTROL GROUP CONTINUED THEIR USUAL CARE AS DIRECTED BY THEIR PHYSICIANS. PATIENTS IN THE YOGA GROUP, IN ADDITION, RECEIVED BIWEEKLY YOGA SESSIONS FOR 12 WK. THE PATIENTS' DEMOGRAPHIC AND HEALTH BEHAVIOUR VARIABLES WERE ASSESSED BEFORE AND AFTER THE YOGA PROGRAMME USING MEDICAL OUTCOMES SHORT FORM (SF-36) FOR QUALITY OF LIFE, PROFILE OF MOOD STATES FOR ASSESSING MOOD AND SYMPTOMS OF STRESS INVENTORY FOR MEASURING STRESS. RESULTS: A TOTAL OF 60 PATIENTS WERE ENROLLED, WITH 8 DROP-OUTS. THIRTY PATIENTS WERE RANDOMIZED TO THE YOGA GROUP AND 30 TO THE CONTROL GROUP. SIGNIFICANT IMPROVEMENTS WERE SEEN IN OVERALL QUALITY OF LIFE, SYMPTOMS OF STRESS, MOOD CHANGES, ALCOHOL DEPENDENCE AND APPETITE AFTER THE 12 WK PERIOD APART FROM THE GENERAL FEELING OF WELL-BEING AND DESIRE TO CONTINUE WITH THE PROGRAMME IN FUTURE IN THE YOGA GROUP, WHILE THERE WAS NO DIFFERENCE IN THE CONTROL GROUP. CONCLUSION: YOGA IS EFFECTIVE ON IMPROVING THE QUALITY OF LIFE IN PATIENTS OF CHRONIC PANCREATITIS.	2007	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
14 1585  37 MEDICAL YOGA FOR PATIENTS WITH STRESS-RELATED SYMPTOMS AND DIAGNOSES IN PRIMARY HEALTH CARE: A RANDOMIZED CONTROLLED TRIAL. AN INCREASING NUMBER OF PATIENTS ARE SUFFERING FROM STRESS-RELATED SYMPTOMS AND DIAGNOSES. THE PURPOSE OF THIS STUDY WAS TO EVALUATE THE MEDICAL YOGA TREATMENT IN PATIENTS WITH STRESS-RELATED SYMPTOMS AND DIAGNOSES IN PRIMARY HEALTH CARE. A RANDOMIZED CONTROLLED STUDY WAS PERFORMED AT A PRIMARY HEALTH CARE CENTRE IN SWEDEN FROM MARCH TO JUNE, 2011. PATIENTS WERE RANDOMLY ALLOCATED TO A CONTROL GROUP RECEIVING STANDARD CARE OR A YOGA GROUP TREATED WITH MEDICAL YOGA FOR 1 HOUR, ONCE A WEEK, OVER A 12-WEEK PERIOD IN ADDITION TO THE STANDARD CARE. A TOTAL OF 37 MEN AND WOMEN, MEAN AGE OF 53 +/- 12 YEARS WERE INCLUDED. GENERAL STRESS LEVEL (MEASURED USING PERCEIVED STRESS SCALE (PSS)), BURNOUT (SHIROM-MELAMED BURNOUT QUESTIONNAIRE (SMBQ)), ANXIETY AND DEPRESSION (HOSPITAL ANXIETY AND DEPRESSION SCALE (HADS)), INSOMNIA SEVERITY (INSOMNIA SEVERITY INDEX (ISI)), PAIN (VISUAL ANALOGUE SCALE (VAS)), AND OVERALL HEALTH STATUS (EURO QUALITY OF LIFE VAS (EQ-VAS)) WERE MEASURED BEFORE AND AFTER 12 WEEKS. PATIENTS ASSIGNED TO THE YOGA GROUP SHOWED SIGNIFICANTLY GREATER IMPROVEMENTS ON MEASURES OF GENERAL STRESS LEVEL (P < 0.000), ANXIETY (P < 0.019), AND OVERALL HEALTH STATUS (P < 0.018) COMPARED TO CONTROLS. TREATMENT WITH MEDICAL YOGA IS EFFECTIVE IN REDUCING LEVELS OF STRESS AND ANXIETY IN PATIENTS WITH STRESS-RELATED SYMPTOMS IN PRIMARY HEALTH CARE.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
15 2521  36 YOGA DECREASES INSOMNIA IN POSTMENOPAUSAL WOMEN: A RANDOMIZED CLINICAL TRIAL. OBJECTIVE: THE PRACTICE OF YOGA HAS BEEN PROVEN TO HAVE POSITIVE EFFECTS ON REDUCING INSOMNIA. STUDIES HAVE ALSO SHOWN ITS EFFECTS ON REDUCING CLIMACTERIC SYMPTOMS. TO DATE, HOWEVER, NO STUDIES THAT EVALUATE THE EFFECTS OF YOGA ON POSTMENOPAUSAL WOMEN WITH A DIAGNOSIS OF INSOMNIA IN A RANDOMIZED CLINICAL TRIAL HAVE BEEN CONDUCTED. THE AIM OF THIS STUDY WAS TO EVALUATE THE EFFECT OF YOGA PRACTICE ON THE PHYSICAL AND MENTAL HEALTH AND CLIMACTERIC SYMPTOMS OF POSTMENOPAUSAL WOMEN WITH A DIAGNOSIS OF INSOMNIA. METHODS: POSTMENOPAUSAL WOMEN NOT UNDERGOING HORMONE THERAPY, WHO WERE 50 TO 65 YEARS OLD, WHO HAD AN APNEA-HYPOPNEA INDEX LESS THAN 15, AND WHO HAD A DIAGNOSIS OF INSOMNIA WERE RANDOMLY ASSIGNED TO ONE OF THREE GROUPS, AS FOLLOWS: CONTROL, PASSIVE STRETCHING, AND YOGA. QUESTIONNAIRES WERE ADMINISTERED BEFORE AND 4 MONTHS AFTER THE INTERVENTION TO EVALUATE QUALITY OF LIFE, ANXIETY AND DEPRESSION SYMPTOMS, CLIMACTERIC SYMPTOMS, INSOMNIA SEVERITY, DAYTIME SLEEPINESS, AND STRESS. THE VOLUNTEERS ALSO UNDERWENT POLYSOMNOGRAPHY. THE STUDY LASTED 4 MONTHS. RESULTS: THERE WERE 44 VOLUNTEERS AT THE END OF THE STUDY. WHEN COMPARED WITH THE CONTROL GROUP, THE YOGA GROUP HAD SIGNIFICANTLY LOWER POSTTREATMENT SCORES FOR CLIMACTERIC SYMPTOMS AND INSOMNIA SEVERITY AND HIGHER SCORES FOR QUALITY OF LIFE AND RESISTANCE PHASE OF STRESS. THE REDUCTION IN INSOMNIA SEVERITY IN THE YOGA GROUP WAS SIGNIFICANTLY HIGHER THAN THAT IN THE CONTROL AND PASSIVE-STRETCHING GROUPS. CONCLUSIONS: THIS STUDY SHOWED THAT A SPECIFIC SEQUENCE OF YOGA MIGHT BE EFFECTIVE IN REDUCING INSOMNIA AND MENOPAUSAL SYMPTOMS AS WELL AS IMPROVING QUALITY OF LIFE IN POSTMENOPAUSAL WOMEN WITH INSOMNIA.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
16 2230  40 THE IMPACT OF YOGA ON FATIGUE IN CANCER SURVIVORSHIP: A META-ANALYSIS. BACKGROUND: MIND-BODY APPROACHES, PARTICULARLY YOGA, ARE USED BY CANCER SURVIVORS TO COPE WITH TREATMENT-RELATED SYMPTOMS. CONSISTENCY OF YOGA-RELATED EFFECTS ON TREATMENT-RELATED SYMPTOMS ARE NOT KNOWN. THIS META-ANALYSIS WAS DESIGNED TO EXAMINE EFFECTS OF YOGA ON PRE- TO POSTINTERVENTION IMPROVEMENTS IN FATIGUE AMONG CANCER PATIENTS. METHODS: PUBMED AND PSYCINFO WERE SEARCHED FOR PEER-REVIEWED ARTICLES OF YOGA RANDOMIZED CONTROLLED TRIALS INCLUDING CANCER SURVIVORS AND REPORTING AT LEAST ONE FATIGUE MEASURE. TWENTY-NINE STUDIES MET INCLUSION CRITERIA (N = 1828 PATIENTS). EFFECT SIZES (HEDGE'S G) WERE CALCULATED FOR FATIGUE, DEPRESSION, AND QUALITY OF LIFE. PATIENT-RELATED AND INTERVENTION-RELATED CHARACTERISTICS WERE TESTED AS MODERATORS OF OUTCOMES. ALL STATISTICAL TESTS WERE TWO-SIDED. RESULTS: YOGA PRACTICE WAS ASSOCIATED WITH A SMALL, STATISTICALLY SIGNIFICANT DECREASE IN FATIGUE (G = 0.45, P = .013). YOGA TYPE WAS A STATISTICALLY SIGNIFICANT MODERATOR OF THIS RELATIONSHIP (P = .02). YOGA WAS ASSOCIATED WITH A MODERATE DECREASE IN DEPRESSION (G = 0.72, P = .007) BUT WAS NOT ASSOCIATED WITH STATISTICALLY SIGNIFICANT CHANGES IN QUALITY OF LIFE (P = .48). SESSION LENGTH WAS A STATISTICALLY SIGNIFICANT MODERATOR OF THE RELATIONSHIP BETWEEN YOGA AND DEPRESSION (P = .004). NEITHER TIMING OF TREATMENT (DURING TREATMENT VS POSTTREATMENT) NOR CLINICAL CHARACTERISTICS WERE STATISTICALLY SIGNIFICANT MODERATORS OF THE EFFECTS OF YOGA ON OUTCOMES. THE EFFECT OF YOGA ON FATIGUE AND DEPRESSION WAS LARGER WHEN THE COMPARATOR WAS A "WAITLIST" OR "USUAL CARE" THAN WHEN THE CONTROL GROUP WAS ANOTHER ACTIVE TREATMENT (P = .036). CONCLUSIONS: RESULTS SUGGEST YOGA MAY BE BENEFICIAL AS A COMPONENT OF TREATMENT FOR BOTH FATIGUE AND DEPRESSION IN CANCER SURVIVORS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
17 2864  34 YOGA-BASED INTERVENTION FOR CAREGIVERS OF OUTPATIENTS WITH PSYCHOSIS: A RANDOMIZED CONTROLLED PILOT STUDY. PURPOSE OF THE STUDY: THE USE OF YOGA AS AN INTERVENTION FOR CAREGIVERS OF PATIENTS WITH PSYCHOSIS HAS BEEN POORLY STUDIED. THE CURRENT STUDY AIMED TO TEST THE EFFICACY OF A BRIEF YOGA PROGRAM AS AN INTERVENTION IN CAREGIVERS OF OUTPATIENTS WITH FUNCTIONAL PSYCHOTIC DISORDERS USING A RANDOMIZED CONTROLLED RESEARCH DESIGN. MATERIALS AND METHODS: CAREGIVERS WHO AGREED TO PARTICIPATE IN THE STUDY (N=29) WERE RANDOMIZED INTO YOGA (N=15) OR WAIT-LIST GROUP (N=14). THEY WERE ASSESSED AT BASELINE AND AT THE END OF 3 MONTHS. PATIENTS WHO WERE RANDOMIZED INTO THE YOGA GROUP WERE OFFERED SUPERVISED YOGA TRAINING THRICE A WEEK FOR 4 WEEKS, AFTER WHICH THEY WERE INSTRUCTED TO PRACTICE AT HOME FOR THE NEXT 2 MONTHS. DUE TO THE SMALL SAMPLE SIZE AND SOME VARIABLES NOT BEING NORMALLY DISTRIBUTED, NON-PARAMETRIC STATISTICAL ANALYSIS WAS USED. RESULTS: RESULTS SHOWED SIGNIFICANTLY REDUCED BURDEN SCORES AND IMPROVED QUALITY OF LIFE SCORES IN THE YOGA GROUP AS COMPARED TO THE WAIT-LIST GROUP AT THE END OF 3 MONTHS. THERE WERE NO SIGNIFICANT CHANGES IN ANXIETY AND DEPRESSION SCORES IN CAREGIVERS, OR PSYCHOPATHOLOGY SCORES IN PATIENTS. CONCLUSION: IN CAREGIVERS OF OUTPATIENTS WITH FUNCTIONAL PSYCHOSIS, 4 WEEKS OF TRAINING FOLLOWED BY 3 MONTHS OF HOME PRACTICE OF A YOGA MODULE OFFERED SIGNIFICANT ADVANTAGE OVER WAITLIST. YOGA CAN BE OFFERED AS AN INTERVENTION FOR CAREGIVERS OF PATIENTS WITH SEVERE MENTAL DISORDERS. METHODS OF PROVIDING YOGA INTERVENTION CLOSER TO THE COMMUNITY OR USE OF FLEXIBLE MODULES AT HOSPITALS NEEDS FURTHER STUDY.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
18 2754  37 YOGA PRACTICE PREDICTS IMPROVEMENTS IN DAY-TO-DAY PAIN IN WOMEN WITH METASTATIC BREAST CANCER. CONTEXT: WOMEN WITH METASTATIC BREAST CANCER (MBC) EXPERIENCE A SIGNIFICANT SYMPTOM BURDEN, INCLUDING CANCER PAIN. YOGA IS A MIND-BODY DISCIPLINE THAT HAS SHOWN PROMISE FOR ALLEVIATING CANCER PAIN, BUT FEW STUDIES HAVE INCLUDED PATIENTS WITH METASTATIC DISEASE OR EXAMINED THE ACUTE EFFECTS OF YOGA PRACTICE. OBJECTIVES: TO DETERMINE WHETHER DAILY PAIN CHANGED SIGNIFICANTLY DURING A RANDOMIZED CONTROLLED TRIAL OF THE MINDFUL YOGA PROGRAM AMONG WOMEN WITH MBC AND WHETHER TIME SPENT IN YOGA PRACTICE WAS RELATED TO DAILY PAIN. METHODS: ON ALTERNATE WEEKS DURING THE INTERVENTION PERIOD, WE COLLECTED DAILY MEASURES OF PAIN FROM A SUBSET OF 48 WOMEN RANDOMIZED TO EITHER YOGA (N = 30) OR A SUPPORT GROUP CONDITION (N = 18). WE ALSO ASSESSED DAILY DURATION OF YOGA PRACTICE AMONG PATIENTS RANDOMIZED TO YOGA. RESULTS: PAIN LEVELS WERE LOW FOR WOMEN IN BOTH CONDITIONS, AND NO DIFFERENTIAL TREATMENT EFFECTS WERE FOUND ON DAILY PAIN. HOWEVER, AMONG WOMEN RANDOMIZED TO YOGA, A DOSE/RESPONSE RELATIONSHIP WAS FOUND BETWEEN YOGA PRACTICE DURATION AND DAILY PAIN. WHEN PATIENTS HAD SPENT RELATIVELY MORE TIME PRACTICING YOGA ACROSS TWO CONSECUTIVE DAYS, THEY WERE MORE LIKELY TO EXPERIENCE LOWER PAIN ON THE NEXT DAY. THIS FINDING IS CONSISTENT WITH AN EARLIER MBC STUDY. MEDITATION PRACTICE SHOWED THE STRONGEST ASSOCIATION WITH LOWER DAILY PAIN. CONCLUSION: FINDINGS SUGGEST THAT YOGA PRACTICE (MEDITATION PRACTICE IN PARTICULAR) IS ASSOCIATED WITH ACUTE IMPROVEMENTS IN CANCER PAIN, AND THAT YOGA INTERVENTIONS MAY BE MORE IMPACTFUL IF TESTED IN A SAMPLE OF PATIENTS WITH ADVANCED CANCER IN WHICH PAIN IS RELATIVELY ELEVATED.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
19 1036  35 EFFECTS OF YOGA IN MANAGING FATIGUE IN BREAST CANCER PATIENTS: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: CANCER-RELATED FATIGUE IS WIDELY PREVALENT IN CANCER PATIENTS AND AFFECTS QUALITY OF LIFE IN ADVANCED CANCER PATIENTS. FATIGUE IS CAUSED DUE TO BOTH PSYCHOLOGIC DISTRESS AND PHYSIOLOGICAL SEQUEL FOLLOWING CANCER PROGRESSION AND ITS TREATMENT. IN THIS STUDY, WE EVALUATE THE EFFECTS OF YOGIC INTERVENTION IN MANAGING FATIGUE IN METASTATIC BREAST CANCER PATIENTS. METHODS: NINETY-ONE PATIENTS WITH METASTATIC BREAST CANCER WERE RANDOMIZED TO RECEIVE INTEGRATED YOGA PROGRAM (N = 46) OR SUPPORTIVE THERAPY AND EDUCATION (N = 45) OVER A 3-MONTH PERIOD. ASSESSMENTS SUCH AS PERCEIVED STRESS, FATIGUE SYMPTOM INVENTORY, DIURNAL SALIVARY CORTISOL, AND NATURAL KILLER CELL COUNTS WERE CARRIED OUT BEFORE AND AFTER INTERVENTION. ANALYSIS WAS DONE USING AN INTENTION-TO-TREAT APPROACH. POSTMEASURES FOR THE ABOVE OUTCOMES WERE ASSESSED USING ANCOVA WITH RESPECTIVE BASELINE MEASURE AS A COVARIATE. RESULTS: THE RESULTS SUGGEST THAT YOGA REDUCES PERCEIVED STRESS (P = 0.001), FATIGUE FREQUENCY (P < 0.001), FATIGUE SEVERITY (P < 0.001), INTERFERENCE (P < 0.001), AND DIURNAL VARIATION (P < 0.001) WHEN COMPARED TO SUPPORTIVE THERAPY. THERE WAS A POSITIVE CORRELATION OF CHANGE IN FATIGUE SEVERITY WITH 9 A.M. SALIVARY CORTISOL LEVELS. CONCLUSION: THE RESULTS SUGGEST THAT YOGA REDUCES FATIGUE IN ADVANCED BREAST CANCER PATIENTS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
20 2553  29 YOGA FOR CHILDREN AND ADOLESCENTS AFTER COMPLETING CANCER TREATMENT. SURVIVORS OF CHILDHOOD CANCER MAY EXPERIENCE PERSISTENT SYMPTOMS, INCLUDING FATIGUE, SLEEP DISTURBANCE, AND BALANCE IMPAIRMENT. YOGA IS A COMPLEMENTARY THERAPY THAT IMPROVES FATIGUE, SLEEP, AND QUALITY OF LIFE IN ADULT CANCER SURVIVORS. USING A ONE GROUP, REPEATED MEASURES DESIGN, WE EVALUATED THE FEASIBILITY OF A YOGA PROGRAM AND ASSESSED IF CANCER SURVIVOR PARTICIPANTS AGES 10 TO 17 YEARS (N = 13) HAD SIGNIFICANTLY LESS FATIGUE AND ANXIETY, AND BETTER BALANCE AND SLEEP, AFTER A 6-WEEK YOGA INTERVENTION COMPARED WITH A 6-WEEK PRE-INTERVENTION WAIT PERIOD. STUDY RECRUITMENT WAS CHALLENGING WITH A 32% ENROLLMENT RATE; YOGA ATTENDANCE WAS 90%. NONE OF THE SCORES FOR ANXIETY, FATIGUE, SLEEP, AND BALANCE HAD SIGNIFICANT CHANGES DURING THE WAIT PERIOD. AFTER THE 6-WEEK YOGA PROGRAM, CHILDREN (N = 7) HAD A SIGNIFICANT DECREASE IN ANXIETY SCORE (P = .04) WHILE ADOLESCENT SCORES (N = 7) SHOWED A DECREASING TREND (P = .10). SCORES FOR FATIGUE, SLEEP, AND BALANCE REMAINED STABLE POST-INTERVENTION. FATIGUE AND BALANCE SCORES WERE BELOW NORMS FOR HEALTH CHILDREN/ADOLESCENTS WHILE SLEEP AND ANXIETY SCORES WERE SIMILAR TO HEALTHY PEERS.	2016