1  648 153 DYADIC YOGA PROGRAM FOR PATIENTS UNDERGOING THORACIC RADIOTHERAPY AND THEIR FAMILY CAREGIVERS: RESULTS OF A PILOT RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: THORACIC RADIOTHERAPY (TRT) MAY RESULT IN TOXICITIES THAT ARE ASSOCIATED WITH PERFORMANCE DECLINES AND POOR QUALITY OF LIFE (QOL) FOR PATIENTS AND THEIR FAMILY CAREGIVERS. THE PURPOSE OF THIS RANDOMIZED CONTROLLED TRIAL WAS TO ESTABLISH FEASIBILITY AND PRELIMINARY EFFICACY OF A DYADIC YOGA (DY) INTERVENTION AS A SUPPORTIVE CARE STRATEGY. METHODS: PATIENTS WITH STAGE I TO III NON-SMALL CELL LUNG OR ESOPHAGEAL CANCER UNDERGOING TRT AND THEIR CAREGIVERS (N = 26 DYADS) WERE RANDOMIZED TO A 15-SESSION DY OR A WAITLIST CONTROL (WLC) GROUP. PRIOR TO TRT AND RANDOMIZATION, BOTH GROUPS COMPLETED MEASURES OF QOL (SF-36) AND DEPRESSIVE SYMPTOMS (CES-D). PATIENTS ALSO COMPLETED THE 6-MINUTE WALK TEST (6MWT). DYADS WERE REASSESSED ON THE LAST DAY OF TRT AND 3 MONTHS LATER. RESULTS: A PRIORI FEASIBILITY CRITERIA WERE MET REGARDING CONSENT (68%), ADHERENCE (80%), AND RETENTION (81%) RATES. CONTROLLING FOR RELEVANT COVARIATES, MULTILEVEL MODELING ANALYSES REVEALED SIGNIFICANT CLINICAL IMPROVEMENTS FOR PATIENTS IN THE DY GROUP COMPARED WITH THE WLC GROUP FOR THE 6MWT (MEANS: DY = 473 M VS WLC = 397 M, D = 1.19) AND SF-36 PHYSICAL FUNCTION (MEANS: DY = 38.77 VS WLC = 30.88; D = .66) AND SOCIAL FUNCTION (MEANS: DY = 45.24 VS WLC = 39.09; D = .44) ACROSS THE FOLLOW-UP PERIOD. CAREGIVERS IN THE DY GROUP REPORTED MARGINALLY CLINICALLY SIGNIFICANT IMPROVEMENTS IN SF-36 VITALITY (MEANS: DY = 53.05 VS WLC = 48.84; D = .39) AND ROLE PERFORMANCE (MEANS: DY = 52.78 VS WLC = 48.59; D = .51) RELATIVE TO THOSE IN THE WLC GROUP. CONCLUSIONS: THIS NOVEL SUPPORTIVE CARE PROGRAM APPEARS TO BE FEASIBLE AND BENEFICIAL FOR PATIENTS UNDERGOING TRT AND THEIR CAREGIVERS. A LARGER EFFICACY TRIAL WITH A MORE STRINGENT CONTROL GROUP IS WARRANTED.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
2 2762  56 YOGA PROGRAM FOR HIGH-GRADE GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR FAMILY CAREGIVERS. BACKGROUND: DESPITE THEIR HIGH SYMPTOM BURDEN AND POOR PROGNOSIS, EVIDENCE-BASED SUPPORTIVE CARE INTERVENTIONS FOR ADULTS WITH HIGH-GRADE GLIOMA (HGG) AND THEIR CAREGIVERS ARE LACKING. THUS, WE AIMED TO ESTABLISH FEASIBILITY OF A PATIENT-CAREGIVER DYADIC YOGA PROGRAM (DYP) FOR NEWLY DIAGNOSED HGG PATIENTS AND THEIR FAMILY CAREGIVERS TARGETING QUALITY-OF-LIFE (QOL) OUTCOMES. METHOD: IN THIS SINGLE-ARM PILOT TRIAL, DYADS PARTICIPATED IN A 12-SESSION DYP PROGRAM ACROSS THE COURSE OF PATIENTS' RADIOTHERAPY. THE INTERVENTION FOCUSED ON BREATHING EXERCISES, GENTLE MOVEMENTS, AND GUIDED MEDITATIONS. WE TRACKED FEASIBILITY DATA AND ASSESSED LEVELS OF CANCER-RELATED SYMPTOMS (MD ANDERSON SYMPTOM INVENTORY [MDASI]), DEPRESSIVE SYMPTOMS (CENTERS FOR EPIDEMIOLOGICAL STUDIES-DEPRESSION SCALE), FATIGUE (BRIEF FATIGUE INVENTORY), SLEEP DISTURBANCES (PITTSBURGH SLEEP QUALITY INDEX [PSQI]), AND OVERALL MENTAL AND PHYSICAL QOL (36-ITEM SHORT-FORM SURVEY [SF-36]) AT BASELINE AND POST-DYP, WHICH WAS AT THE END OF RADIOTHERAPY. RESULTS: WE APPROACHED 6 DYADS OF WHICH 5 DYADS (86%) CONSENTED AND COMPLETED ALL 12 SESSIONS AND PRE/POST ASSESSMENTS. ALL PATIENTS (MEAN AGE: 52 YEARS, 80% FEMALE, 80% GRADE IV) AND CAREGIVERS (MEAN AGE: 58 YEARS, 80% FEMALE, 60% SPOUSES) PERCEIVED BENEFIT FROM THE PROGRAM. PAIRED T TESTS REVEALED A MARGINALLY SIGNIFICANT, YET CLINICALLY MEANINGFUL, DECREASE IN PATIENT'S CANCER SYMPTOMS ( T = 2.32, P = .08; MDASI MEAN; PRE = 1.75, POST = 1.04). THERE WERE CLINICALLY SIGNIFICANT REDUCTIONS IN PATIENT SLEEP DISTURBANCES (PSQI MEAN: PRE = 10.75, POST = 8.00) AND IMPROVEMENTS IN PATIENT AND CAREGIVER MENTAL QOL (MCS OF SF-36 MEAN: PRE = 42.35, POST = 52.34, AND PRE = 45.14, POST = 51.43, RESPECTIVELY). CONCLUSIONS: THIS NOVEL SUPPORTIVE CARE PROGRAM APPEARS TO BE SAFE, FEASIBLE, ACCEPTABLE, AND SUBJECTIVELY USEFUL FOR HGG PATIENTS AND THEIR CAREGIVERS. THERE WAS ALSO PRELIMINARY EVIDENCE REGARDING QOL TREATMENT GAINS FOR BOTH PATIENTS AND CAREGIVERS.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
3 2361  54 VIVEKANANDA YOGA PROGRAM FOR PATIENTS WITH ADVANCED LUNG CANCER AND THEIR FAMILY CAREGIVERS. BACKGROUND: THE PRIMARY PURPOSE OF THIS STUDY WAS TO ESTABLISH THE FEASIBILITY OF A COUPLE-BASED VIVEKANANDA YOGA (VKC) INTERVENTION IN LUNG CANCER PATIENTS AND CAREGIVERS. SECONDLY, WE EXAMINED PRELIMINARY EFFICACY REGARDING QUALITY OF LIFE (QOL) OUTCOMES. METHOD: IN THIS SINGLE-ARM FEASIBILITY TRIAL, PATIENTS WITH LUNG CANCER UNDERGOING RADIOTHERAPY AND THEIR CAREGIVERS PARTICIPATED IN A 15-SESSION VKC PROGRAM THAT FOCUSED ON THE INTERCONNECTEDNESS OF THE DYAD. WE ASSESSED PRE-AND POST-INTERVENTION LEVELS OF FATIGUE, SLEEP DISTURBANCES, PSYCHOLOGICAL DISTRESS, OVERALL QOL, SPIRITUALITY, AND RELATIONAL CLOSENESS. WE TRACKED FEASIBILITY DATA, AND PARTICIPANTS COMPLETED PROGRAM EVALUATIONS. RESULTS: WE APPROACHED 28 ELIGIBLE DYADS OF WHICH 15 (53%) CONSENTED AND 9 (60%) COMPLETED THE INTERVENTION. PATIENTS (MEAN AGE = 73 YEARS, 63% FEMALE, ALL STAGE III) AND CAREGIVERS (MEAN AGE = 62 YEARS, 38% FEMALE, 63% SPOUSES) COMPLETED A MEAN OF 10 SESSIONS AND 95.5% OF THEM RATED THE PROGRAM AS VERY USEFUL. PAIRED T TESTS REVEALED A SIGNIFICANT INCREASE IN PATIENTS' MENTAL HEALTH (D = 0.84; P = .04) AND A SIGNIFICANT DECREASE IN CAREGIVERS' SLEEP DISTURBANCES (D = 1.44; P = .02). ALTHOUGH NOT STATISTICALLY SIGNIFICANT, FOR PATIENTS, EFFECT SIZES FOR CHANGE SCORES WERE MEDIUM FOR BENEFIT FINDING AND SMALL FOR DISTRESS (D = 0.65 AND 0.37, RESPECTIVELY). FOR CAREGIVERS, MEDIUM EFFECTS WERE FOUND FOR IMPROVEMENT IN PHYSICAL FUNCTIONING (D = 0.50). CONCLUSION: THIS NOVEL SUPPORTIVE CARE PROGRAM APPEARS TO BE SAFE, FEASIBLE, ACCEPTABLE, AND SUBJECTIVELY USEFUL FOR LUNG CANCER PATIENTS AND THEIR CAREGIVERS AND LENDS SUPPORT FOR FURTHER STUDY.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
4  199  53 A RESEARCH PROTOCOL FOR A PILOT, RANDOMIZED CONTROLLED TRIAL DESIGNED TO EXAMINE THE FEASIBILITY OF A DYADIC VERSUS INDIVIDUAL YOGA PROGRAM FOR FAMILY CAREGIVERS OF GLIOMA PATIENTS UNDERGOING RADIOTHERAPY. BACKGROUND: ALTHOUGH THE DIAGNOSIS AND TREATMENT OF A PRIMARY BRAIN TUMOR PRESENT UNIQUE CHALLENGES TO PATIENTS AND THEIR FAMILY CAREGIVERS, EVIDENCE-BASED SUPPORTIVE CARE INTERVENTIONS ARE GENERALLY LACKING. THE PRIMARY AIM OF THIS RESEARCH PROTOCOL IS TO DETERMINE THE FEASIBILITY OF IMPLEMENTING A DYADIC YOGA (DY) VERSUS A CAREGIVER YOGA (CY) INTERVENTION OR A WAIT-LIST CONTROL (WLC) GROUP USING A RANDOMIZED CONTROLLED TRIAL DESIGN. METHODS: SEVENTY-FIVE GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR FAMILY CAREGIVERS ARE RANDOMIZED TO THE DY, CY, OR A WLC GROUP. PATIENT-CAREGIVER DYADS IN THE DY GROUP AND CAREGIVERS IN THE CY GROUP RECEIVE 15 SESSIONS (45 MIN EACH) OVER THE COURSE OF PATIENTS' STANDARD RADIOTHERAPY (6 WEEKS). PATIENTS AND CAREGIVERS IN ALL GROUPS COMPLETE BASELINE ASSESSMENTS OF SYMPTOMS, QUALITY OF LIFE (QOL), AND HEALTH UTILIZATION OUTCOMES PRIOR TO RANDOMIZATION. FOLLOW-UP ASSESSMENTS ARE PERFORMED 6 WEEKS AND THEN AGAIN 3 MONTHS LATER. THE PRIMARY OUTCOME IS FEASIBILITY (I.E., >/= 50% OF ELIGIBLE DYADS CONSENT, >/= 70% OF ENROLLED DYADS COMPLETE ALL ASSESSMENTS, AND >/= 50% OF ALL PRACTICE SESSIONS ARE ATTENDED). WE WILL ALSO PERFORM PRIMARILY DESCRIPTIVE ANALYSES OF THE SELF-REPORTED OUTCOMES (E.G., FATIGUE, OVERALL QOL) AND EXPLORE POTENTIAL INTERVENTION MODERATORS (E.G., PERFORMANCE STATUS) TO INFORM A LARGER FUTURE TRIAL. CONCLUSION: THIS TRIAL WILL PROVIDE IMPORTANT INFORMATION REGARDING THE FEASIBILITY OF A DYADIC VERSUS A CAREGIVER YOGA INTERVENTION REGARDING SYMPTOM, QOL, AND HEALTH UTILIZATION OUTCOMES IN GLIOMA PATIENTS AND THEIR CAREGIVERS. TRIAL REGISTRATION: CLINICALTRIALS.GOV NCT02481349.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
5 2167  37 THE EFFECTS OF YOGA IN HELPING CANCER PATIENTS AND CAREGIVERS MANAGE THE STRESS OF A NATURAL DISASTER: A BRIEF REPORT ON HURRICANE HARVEY. BACKGROUND: THIS SMALL QUALITATIVE STUDY REPORTS ON THE EXPERIENCES OF PATIENTS AND FAMILY CAREGIVERS WHO PARTICIPATED IN A DYADIC YOGA PILOT TRIAL WHILE UNDERGOING CANCER TREATMENT IN THE MIDST OF HURRICANE HARVEY. OUR PRIMARY PURPOSE WAS TO DETERMINE IF PARTICIPANTS IMPLEMENTED COMPONENTS OF THE PROGRAM TO COPE WITH THE STRESSORS ASSOCIATED WITH HURRICANE HARVEY AND IF THEY PERCEIVED BENEFITS FROM THE YOGA PRACTICES. METHODS: WE ADMINISTERED BRIEF SEMISTRUCTURED INTERVIEWS TO THE DYADS PARTICIPATING IN A DYADIC YOGA PILOT TRIAL. PARTICIPANTS (N = 5 DYADS) WERE ASKED TO DISCUSS THEIR EXPERIENCE WITH HURRICANE HARVEY, INCLUDING FACTORS THAT HELPED THEM COPE WITH THE EVENT WHILE RECEIVING TREATMENT. RESULT: PATIENTS HAD A MEAN AGE OF 55.6 YEARS, WERE MOSTLY NON-HISPANIC WHITE, MALE, AND HAD ADVANCE STAGE HEAD AND NECK CANCER. CAREGIVERS HAD A MEAN AGE OF 58 YEARS AND WERE MAINLY NON-HISPANIC WHITE AND FEMALE. ANALYSES OF THE INTERVIEWS REVEALED 2 OVERARCHING THEMES: (1) THE STORM'S NEGATIVE IMPACT AND (2) THE USE OF YOGA TO COPE WITH THE HURRICANE-RELATED STRESSORS. CONCLUSIONS: PATIENT-CAREGIVER DYADS EXPERIENCED PSYCHOLOGICAL DISTRESS DURING THE STORM AND/OR ITS AFTERMATH. DYADS USED YOGA TECHNIQUES TO COPE WITH THESE PSYCHOLOGICAL STRESSORS. YOGA SERVED AS A MEANS OF SOCIAL SUPPORT AS DYADS EITHER PARTICIPATED IN THESE ACTIVITIES TOGETHER OR WITH OTHER FAMILY MEMBERS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
6   97  30 A NONRANDOMIZED COMPARISON STUDY OF SELF-HYPNOSIS, YOGA, AND COGNITIVE-BEHAVIORAL THERAPY TO REDUCE EMOTIONAL DISTRESS IN BREAST CANCER PATIENTS. THE AUTHORS ASKED BREAST CANCER (BC) PATIENTS TO PARTICIPATE IN 1 OF 3 MIND-BODY INTERVENTIONS (COGNITIVE-BEHAVIORAL THERAPY (CBT), YOGA, OR SELF-HYPNOSIS) TO EXPLORE THEIR FEASIBILITY, EASE OF COMPLIANCE, AND IMPACT ON THE PARTICIPANTS' DISTRESS, QUALITY OF LIFE (QOL), SLEEP, AND MENTAL ADJUSTMENT. NINETY-NINE PATIENTS COMPLETED AN INTERVENTION (CBT: N = 10; YOGA: N = 21; AND SELF-HYPNOSIS: N = 68). RESULTS SHOWED HIGH FEASIBILITY AND HIGH COMPLIANCE. AFTER THE INTERVENTIONS, THERE WAS NO SIGNIFICANT EFFECT IN THE CBT GROUP BUT SIGNIFICANT POSITIVE EFFECTS ON DISTRESS IN THE YOGA AND SELF-HYPNOSIS GROUPS, AND, ALSO, ON QOL, SLEEP, AND MENTAL ADJUSTMENT IN THE SELF-HYPNOSIS GROUP. IN CONCLUSION, MIND-BODY INTERVENTIONS CAN DECREASE DISTRESS IN BC PATIENTS, BUT RCTS ARE NEEDED TO CONFIRM THESE FINDINGS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
7 1748  84 PILOT RANDOMIZED, CONTROLLED TRIAL OF A DYADIC YOGA PROGRAM FOR GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR FAMILY CAREGIVERS. BACKGROUND: WHILE THE USE OF BEHAVIORAL MEDICINE IN MANAGING GLIOMA PATIENTS' SYMPTOMS IS NOT WELL STUDIED, THE HIGH SYMPTOM BURDEN IN PATIENTS AND THEIR FAMILY CAREGIVERS IS WELL ESTABLISHED. WE CONDUCTED A PILOT RANDOMIZED, CONTROLLED TRIAL TO EXAMINE THE FEASIBILITY AND PRELIMINARY EFFICACY OF A DYADIC YOGA (DY) INTERVENTION AS A SUPPORTIVE CARE STRATEGY. METHODS: GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR CAREGIVERS WERE RANDOMIZED TO A 12-SESSION DY OR WAITLIST CONTROL (WLC) GROUP. PRIOR TO RADIOTHERAPY AND RANDOMIZATION, BOTH GROUPS COMPLETED MEASURES OF CANCER-RELATED SYMPTOMS (MD ANDERSON SYMPTOM INVENTORY-BRAIN TUMOR MODULE), DEPRESSIVE SYMPTOMS (CENTER FOR EPIDEMIOLOGICAL STUDIES-DEPRESSION MEASURE), FATIGUE (BRIEF FATIGUE INVENTORY), AND OVERALL QUALITY OF LIFE (QOL; MEDICAL OUTCOMES STUDY 36-ITEM SHORT-FORM SURVEY). DYADS WERE REASSESSED AT THE LAST DAY OF RADIOTHERAPY. RESULTS: TWENTY PATIENTS (MEAN AGE: 46 YEARS, 50% FEMALE, 80% WHO GRADE IV AND CAREGIVERS (MEAN AGE: 50 YEARS, 70% FEMALE, 50% SPOUSES) PARTICIPATED IN THE TRIAL. A PRIORI FEASIBILITY CRITERIA WERE MET REGARDING CONSENT (70%), ADHERENCE (88%), AND RETENTION (95%) RATES. CONTROLLING FOR RELEVANT COVARIATES, CHANGE SCORE ANALYSES REVEALED CLINICALLY SIGNIFICANT IMPROVEMENTS FOR PATIENTS IN THE DY COMPARED WITH THE WLC GROUP FOR OVERALL CANCER SYMPTOM SEVERITY (D = 0.96) AND SYMPTOM INTERFERENCE (D = 0.74), DEPRESSIVE SYMPTOMS (D = 0.71), AND MENTAL QOL (D = 0.69). CAREGIVERS IN THE DY GROUP REPORTED CLINICALLY SIGNIFICANT IMPROVEMENTS IN DEPRESSIVE SYMPTOMS (D = 1.12), FATIGUE (D = 0.89), AND MENTAL QOL (D = 0.49) RELATIVE TO THOSE IN THE WLC GROUP. CONCLUSION: A DY INTERVENTION APPEARS TO BE A FEASIBLE AND BENEFICIAL SYMPTOM AND QOL MANAGEMENT STRATEGY FOR GLIOMA PATIENTS UNDERGOING RADIOTHERAPY AND THEIR CAREGIVERS. AN EFFICACY TRIAL WITH A MORE STRINGENT CONTROL GROUP IS WARRANTED. CLINICAL TRIAL NUMBER: NCT02481349.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
8 2653  46 YOGA IMPROVES OCCUPATIONAL PERFORMANCE, DEPRESSION, AND DAILY ACTIVITIES FOR PEOPLE WITH CHRONIC PAIN. BACKGROUND: CHRONIC PAIN IS A COMPLEX ACCUMULATION OF PHYSICAL, PSYCHOLOGICAL, AND SOCIAL CONDITIONS, THUS INTERVENTIONS THAT ADDRESS PAIN AND PROMOTE OCCUPATIONAL PERFORMANCE ARE NEEDED. A HOLISTIC INTERVENTION, WITH MIND AND BODY COMPONENTS, IS LIKELY NECESSARY TO BEST TREAT THE COMPLEXITIES OF CHRONIC PAIN. THUS, WE DEVELOPED AND TESTED A YOGA INTERVENTION FOR PEOPLE WITH CHRONIC PAIN. OBJECTIVES: IN A RANDOMIZED CONTROL TRIAL (RCT), PARTICIPANTS WITH CHRONIC PAIN WERE RANDOMIZED TO A YOGA INTERVENTION OR USUAL CARE GROUP. BETWEEN AND WITHIN GROUP DIFFERENCES FOR PRE-AND POST-OUTCOME MEASURE SCORES WERE ASSESSED FOR: OCCUPATIONAL PERFORMANCE, COMPLETION OF ACTIVITIES, AND DEPRESSION. METHODS: PILOT RCT WITH PARTICIPANT ALLOCATION TO 8 WEEKS OF YOGA OR USUAL CARE. BOTH GROUPS RECEIVED ONGOING MONTHLY SELF-MANAGEMENT PROGRAMMING. DATA WERE COLLECTED BEFORE AND AFTER THE 8-WEEK INTERVENTION. PARTICIPANTS WERE RANDOMIZED TO YOGA OR USUAL CARE AFTER BASELINE ASSESSMENTS. DEMOGRAPHICS WERE COLLECTED AND MEASURES INCLUDED: CANADIAN OCCUPATIONAL PERFORMANCE MEASURE (COPM) TO ASSESS OCCUPATIONAL PERFORMANCE; THE 15-ITEM FRENCHAY ACTIVITIES INDEX (FAI)(ACTIVITIES); AND THE 9-ITEM PATIENT HEALTH QUESTIONNAIRE (PHQ-9) FOR DEPRESSION. INDEPENDENT T-TESTS WERE USED TO ASSESS DIFFERENCES BETWEEN GROUPS. PAIRED T-TESTS WERE USED TO ASSESS DIFFERENCES BETWEEN PRE- AND POST 8-WEEK INTERVENTION FOR BOTH THE YOGA AND THE USUAL CARE GROUPS. PERCENT CHANGE SCORES AND EFFECT SIZES WERE CALCULATED. RESULTS: 83 PEOPLE WERE RECRUITED FOR THE STUDY AND COMPLETED BASELINE ASSESSMENTS; 44 INDIVIDUALS WERE RANDOMIZED TO YOGA AND 39 TO THE CONTROL GROUP. THE AVERAGE AGE OF ALL PARTICIPANTS WAS 51.4+/-10.5 YEARS, 68% WERE FEMALE; AND 60% HAD AT LEAST SOME COLLEGE EDUCATION. THERE WERE NO SIGNIFICANT DIFFERENCES IN DEMOGRAPHICS OR OUTCOME MEASURES BETWEEN GROUPS AT BASELINE OR 8 WEEKS; HOWEVER, THE STUDY WAS NOT POWERED TO SEE SUCH DIFFERENCES. INDIVIDUALS RANDOMIZED TO THE CONTROL GROUP DID NOT SIGNIFICANTLY IMPROVE IN ANY OUTCOME MEASURE OVER THE 8 WEEKS. THERE WERE SIGNIFICANT IMPROVEMENTS IN COPM PERFORMANCE AND COPM SATISFACTION SCORES FOR INDIVIDUALS RANDOMIZED TO THE YOGA GROUP; BOTH SCORES SIGNIFICANTLY IMPROVED. COPM PERFORMANCE IMPROVED BY 27% WITH A MODERATE TO LARGE EFFECT SIZE (3.66+/-1.85 VS 4.66+/-1.93, P < 0.001, D = 0.76). COPM SATISFACTION SIGNIFICANTLY IMPROVED BY 78% (2.14+/-2.31 VS. 3.80+/-2.50, P < 0.001) AND HAD A LARGE EFFECTS SIZE (D = 1.02). FAI SCORES IMPROVED, INDICATING INCREASED ACTIVITY OR ENGAGEMENT IN DAILY OCCUPATION DURING THE 8-WEEK INTERVENTION. SCORES INCREASED BY 5% (38.13+/-8.48 VS. 39.90+/-8.57, P = 0.024) WITH A SMALL EFFECT SIZE (D = 0.37). DEPRESSION SIGNIFICANTLY DECREASED FROM 13.21+/-5.60 TO 11.41+/-5.82, P = 0.041, WITH A SMALL EFFECT SIZE. CONCLUSION: DATA FROM THIS PILOT RCT INDICATE YOGA MAY BE AN EFFECTIVE THERAPEUTIC INTERVENTION WITH PEOPLE IN CHRONIC PAIN TO IMPROVE OCCUPATIONAL PERFORMANCE, INCREASE ENGAGEMENT IN ACTIVITIES, AND DECREASE DEPRESSION. OCCUPATIONAL THERAPY PRACTITIONERS MAY CONSIDER ADDING YOGA AS A TREATMENT INTERVENTION TO ADDRESS THE NEEDS OF PEOPLE WITH PAIN.	2019	

9 1171  39 EVALUATION OF A SPECIALIZED YOGA PROGRAM FOR PERSONS WITH A SPINAL CORD INJURY: A PILOT RANDOMIZED CONTROLLED TRIAL. OBJECTIVES: THE PURPOSE OF THIS RANDOMIZED CONTROLLED TRIAL WAS TO EVALUATE THE EFFECTS OF A SPECIALIZED YOGA PROGRAM FOR INDIVIDUALS WITH A SPINAL CORD INJURY (SCI) ON PAIN, PSYCHOLOGICAL, AND MINDFULNESS VARIABLES. MATERIALS AND METHODS: PARTICIPANTS WITH SCI (N=23) WERE OUTPATIENTS OR COMMUNITY MEMBERS AFFILIATED WITH A REHABILITATION HOSPITAL. PARTICIPANTS WERE RANDOMIZED TO AN IYENGAR YOGA (IY; N=11) GROUP OR TO A 6-WEEK WAIT-LIST CONTROL (WLC; N=12) GROUP. THE IY GROUP PARTICIPATED IN A TWICE-WEEKLY 6-WEEK SEATED IY PROGRAM; THE WLC GROUP PARTICIPATED IN THE SAME YOGA PROGRAM, AFTER THE IY GROUP'S YOGA PROGRAM HAD ENDED. PAIN, PSYCHOLOGICAL, AND MINDFULNESS MEASURES WERE COLLECTED AT TWO TIME POINTS FOR BOTH GROUPS (WITHIN 1-2 WEEKS BEFORE AND AFTER PROGRAM 1 AND AT A THIRD TIME POINT FOR THE WLC GROUP (WITHIN 1 WEEK AFTER PROGRAM 2). RESULTS: LINEAR MIXED-EFFECT GROWTH MODELS WERE CONDUCTED TO EVALUATE THE MAIN EFFECTS OF GROUP AT T2 (POSTINTERVENTION), CONTROLLING FOR T1 (PREINTERVENTION) SCORES. T2 DEPRESSION SCORES WERE LOWER (F1,18=6.1, P<0.05) AND T2 SELF-COMPASSION SCORES HIGHER (F1,18=6.57, P< 0.05) IN THE IY GROUP COMPARED TO THE WLC GROUP. TO INCREASE SAMPLE SIZE AND POWER, THE TWO GROUPS WERE COMBINED AND ANALYZED ACROSS TIME BY COMPARING PRE- AND POSTINTERVENTION SCORES. MAIN EFFECTS OF TIME WERE FOUND FOR DEPRESSION SCORES, (F1,14.83=6.62, P<0.05), SELF-COMPASSION, (F1,16.6=4.49, P<0.05), MINDFULNESS (F1,16.79=5.42, P<0.05), MINDFUL OBSERVING (F1,19.82=5.06, P<0.05), AND MINDFUL NONREACTIVITY, (F1,16.53=4.92, P<0.05), ALL SHOWING IMPROVEMENT AFTER THE INTERVENTION. DISCUSSION: THE RESULTS INDICATED THAT A SPECIALIZED 6-WEEK YOGA INTERVENTION REDUCED DEPRESSIVE SYMPTOMS AND INCREASED SELF-COMPASSION IN INDIVIDUALS WITH SCI, AND MAY ALSO HAVE FOSTERED GREATER MINDFULNESS.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
10 1232  57 FEASIBILITY AND POTENTIAL BENEFITS OF PARTNER-SUPPORTED YOGA ON PSYCHOSOCIAL AND PHYSICAL FUNCTION AMONG LUNG CANCER PATIENTS. OBJECTIVE: PATIENTS WITH LUNG CANCER EXPERIENCE SIGNIFICANT DECLINES IN PSYCHOSOCIAL AND PHYSICAL FUNCTION DURING AND AFTER TREATMENT THAT IMPACT QUALITY OF LIFE (QOL) AND SURVIVAL. YOGA IS A POTENTIAL STRATEGY TO MITIGATE FUNCTIONAL DECLINE AMONG PATIENTS WITH LUNG CANCER. METHODS: A SINGLE GROUP 12-WEEK PILOT TRIAL OF LOW-MODERATE INTENSITY YOGA AMONG PATIENTS WITH STAGE I-IV LUNG CANCER AND THEIR PARTNERS (N = 46; 23 PATIENT-PARTNER DYADS) DURING CANCER TREATMENT FROM TWO HOSPITAL SYSTEMS. FEASIBILITY, ACCEPTABILITY, DESCRIPTIVE STATISTICS, AND COHEN D EFFECT SIZES WERE CALCULATED AT 6 AND 12-WEEKS FOR PSYCHOSOCIAL AND PHYSICAL OUTCOMES USING VALIDATED QUESTIONNAIRES AND ASSESSMENTS. RESULTS: AT 6 AND 12-WEEKS, RETENTION WAS 65% AND WITHDRAWALS WERE MAINLY DUE TO DISEASE PROGRESSION. AMONG STUDY COMPLETERS (N = 26; 13 DYADS) ADHERENCE WAS 80%. COMPARING BASELINE TO 12-WEEK MEASUREMENTS, FATIGUE, DEPRESSION SYMPTOMS, AND SLEEP DISTURBANCE IMPROVED IN 54% OF PARTICIPANTS FOR ALL THREE MEASURES (COHEN'S D = 0.40-0.53). QOL IMPROVED IN 77% OF PARTICIPANTS (COHEN'S D = 0.34). UPPER AND LOWER BODY FLEXIBILITY, AND LOWER BODY STRENGTH IMPROVED IN 92%, 85% AND 77% OF PARTICIPANTS, RESPECTIVELY (COHEN'S D = 0.39-1.08). SIX-MINUTE WALK TEST IMPROVED IN 62% OF PARTICIPANTS AN AVERAGE OF 32 METERS (SD = 11.3; COHEN'S D = 0.17). NO SERIOUS ADVERSE EVENTS WERE REPORTED. CONCLUSIONS: AMONG PATIENTS WITH STAGE I-IV LUNG CANCER INCLUDING ACTIVE TREATMENT, A 12-WEEK PARTNER-SUPPORTED YOGA PROGRAM IS FEASIBLE, ACCEPTABLE, AND IMPROVED PSYCHOSOCIAL AND PHYSICAL FUNCTION. LOW-INTENSITY YOGA MAY BE A COMPLIMENTARY APPROACH TO REDUCE THE EFFECTS OF CANCER TREATMENT, HOWEVER, MORE RESEARCH IS NEEDED TO DETERMINE THE EFFICACY OF PARTNER-SUPPORTED YOGA TO MITIGATE FUNCTIONAL DECLINE.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
11 1245  46 FEASIBILITY OF IMPLEMENTING A COMMUNITY-BASED RANDOMIZED TRIAL OF YOGA FOR WOMEN UNDERGOING CHEMOTHERAPY FOR BREAST CANCER. BACKGROUND: TREATMENT-RELATED SYMPTOMS AND DECREASED HEALTH-RELATED QUALITY OF LIFE (HRQOL) FREQUENTLY OCCUR DURING CHEMOTHERAPY FOR BREAST CANCER. ALTHOUGH RESEARCH FINDINGS SUGGEST THAT YOGA CAN REDUCE SYMPTOMS AND IMPROVE HRQOL AFTER TREATMENT, POTENTIAL BENEFITS OF YOGA DURING CHEMOTHERAPY HAVE RECEIVED MINIMAL ATTENTION. OBJECTIVE: TO ESTIMATE ACCRUAL, ADHERENCE, STUDY RETENTION, AND PRELIMINARY EFFICACY OF A YOGA INTERVENTION COMPARED WITH AN ACTIVE CONTROL GROUP FOR BREAST CANCER PATIENTS DURING CHEMOTHERAPY. METHODS: WOMEN WITH STAGE I-III BREAST CANCER WERE RECRUITED FROM 3 COMMUNITY CANCER CLINICS AND RANDOMIZED TO 10 WEEKS OF GENTLE YOGA OR WELLNESS EDUCATION. DEPRESSIVE SYMPTOMS, FATIGUE, SLEEP, AND HRQOL WERE ASSESSED AT BASELINE, MID-INTERVENTION (WEEK 5), AND AFTER INTERVENTION (WEEK 10). RESULTS: 40 WOMEN AGED 29-83 YEARS (MEDIAN, 48 YEARS; 88% WHITE) WERE RANDOMIZED TO YOGA (N = 22) OR WELLNESS EDUCATION (N = 18). THE GROUPS DID NOT DIFFER SIGNIFICANTLY ON BASELINE CHARACTERISTICS, ADHERENCE, OR STUDY RETENTION. PARTICIPANT FEEDBACK WAS POSITIVE AND COMPARABLE BETWEEN GROUPS. MEANINGFUL WITHIN-GROUP DIFFERENCES WERE IDENTIFIED FOR SLEEP ADEQUACY AND QUANTITY IN YOGA PARTICIPANTS AND FOR SOMNOLENCE IN WELLNESS-EDUCATION PARTICIPANTS. LIMITATIONS: SMALL SAMPLE SIZE AND LACK OF A USUAL-CARE CONTROL GROUP. CONCLUSIONS: THIS STUDY ESTABLISHED FEASIBILITY OF A COMMUNITY-BASED RANDOMIZED TRIAL OF YOGA AND AN ACTIVE COMPARISON GROUP FOR WOMEN UNDERGOING CHEMOTHERAPY FOR BREAST CANCER. PRELIMINARY EFFICACY ESTIMATES SUGGEST THAT YOGA IMPROVES SLEEP ADEQUACY SYMPTOM SEVERITY AND INTERFERENCE REMAINED STABLE DURING CHEMOTHERAPY FOR THE YOGA GROUP AND SNOWED A TREND TOWARD INCREASING IN THE CONTROL GROUP. THE STUDY HIGHLIGHTED OBSTACLES TO MULTISITE YOGA RESEARCH DURING CANCER TREATMENT. FUNDING/SPONSORSHIP: NATIONAL CANCER INSTITUTE (3U10 CA081851, PI; SHAW; R25 CA122061, PI: AVIS); TRANSLATIONAL SCIENCE INSTITUTE, WAKE FOREST SCHOOL OF MEDICINE.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
12 1868  47 RANDOMIZED, CONTROLLED TRIAL OF YOGA IN WOMEN WITH BREAST CANCER UNDERGOING RADIOTHERAPY. PURPOSE: PREVIOUS RESEARCH INCORPORATING YOGA (YG) INTO RADIOTHERAPY (XRT) FOR WOMEN WITH BREAST CANCER FINDS IMPROVED QUALITY OF LIFE (QOL). HOWEVER, SHORTCOMINGS IN THIS RESEARCH LIMIT THE FINDINGS. PATIENTS AND METHODS: PATIENTS WITH STAGES 0 TO III BREAST CANCER WERE RECRUITED BEFORE STARTING XRT AND WERE RANDOMLY ASSIGNED TO YG (N = 53) OR STRETCHING (ST; N = 56) THREE TIMES A WEEK FOR 6 WEEKS DURING XRT OR WAITLIST (WL; N = 54) CONTROL. SELF-REPORT MEASURES OF QOL (MEDICAL OUTCOMES STUDY 36-ITEM SHORT-FORM SURVEY; PRIMARY OUTCOMES), FATIGUE, DEPRESSION, AND SLEEP QUALITY, AND FIVE SALIVA SAMPLES PER DAY FOR 3 CONSECUTIVE DAYS WERE COLLECTED AT BASELINE, END OF TREATMENT, AND 1, 3, AND 6 MONTHS LATER. RESULTS: THE YG GROUP HAD SIGNIFICANTLY GREATER INCREASES IN PHYSICAL COMPONENT SCALE SCORES COMPARED WITH THE WL GROUP AT 1 AND 3 MONTHS AFTER XRT (P = .01 AND P = .01). AT 1, 3, AND 6 MONTHS, THE YG GROUP HAD GREATER INCREASES IN PHYSICAL FUNCTIONING COMPARED WITH BOTH ST AND WL GROUPS (P < .05), WITH ST AND WL DIFFERENCES AT ONLY 3 MONTHS (P < .02). THE GROUP DIFFERENCES WERE SIMILAR FOR GENERAL HEALTH REPORTS. BY THE END OF XRT, THE YG AND ST GROUPS ALSO HAD A REDUCTION IN FATIGUE (P < .05). THERE WERE NO GROUP DIFFERENCES FOR MENTAL HEALTH AND SLEEP QUALITY. CORTISOL SLOPE WAS STEEPEST FOR THE YG GROUP COMPARED WITH THE ST AND WL GROUPS AT THE END (P = .023 AND P = .008) AND 1 MONTH AFTER XRT (P = .05 AND P = .04). CONCLUSION: YG IMPROVED QOL AND PHYSIOLOGICAL CHANGES ASSOCIATED WITH XRT BEYOND THE BENEFITS OF SIMPLE ST EXERCISES, AND THESE BENEFITS APPEAR TO HAVE LONG-TERM DURABILITY.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
13 2207  39 THE FEASIBILITY AND BENEFITS OF A 12-WEEK YOGA INTERVENTION FOR PEDIATRIC CANCER OUT-PATIENTS. BACKGROUND: INCREASING RATES OF SURVIVAL PRESENT A NEW SET OF PSYCHOSOCIAL AND PHYSICAL CHALLENGES FOR CHILDREN UNDERGOING TREATMENT FOR CANCER. PHYSICAL ACTIVITY (PA) HAS BEEN SHOWN TO BE A SAFE AND EFFECTIVE STRATEGY TO MITIGATE THE SIGNIFICANT BURDEN OF CANCER AND ITS TREATMENTS, WITH YOGA INCREASINGLY GAINING RECOGNITION AS A GENTLE ALTERNATIVE. THE PURPOSE OF THIS STUDY WAS TO DETERMINE THE FEASIBILITY AND BENEFITS OF A 12-WEEK COMMUNITY-BASED YOGA INTERVENTION ON HEALTH-RELATED QUALITY OF LIFE (HRQL), SELECT PHYSICAL FITNESS OUTCOMES AND PA LEVELS (PAL). PROCEDURE: EIGHT PEDIATRIC CANCER OUT-PATIENTS (4 MALE; 4 FEMALE; MAGE = 11.88, SD = 4.26) PARTICIPATED IN THE 12-WEEK INTERVENTION CONSISTING OF SUPERVISED YOGA SESSIONS 2 TIMES/WEEK. PARTICIPANTS (PATIENTS AND PARENT PROXIES) COMPLETED MEASURES ASSESSING HRQL, PHYSICAL FITNESS AND PAL AT BASELINE AND POST-INTERVENTION. RESULTS: RATES OF RECRUITMENT, RETENTION, ATTENDANCE AND ADVERSE EVENTS INDICATED THE PROGRAM WAS FEASIBLE. WILCOXON SIGNED RANK TESTS INDICATED SIGNIFICANT IMPROVEMENTS FOR PATIENT (P = 0.02) AND PARENT REPORTED HRQL (P = 0.03), FUNCTIONAL MOBILITY (P = 0.01), HAMSTRING FLEXIBILITY (LEFT, P = 0.01 AND RIGHT P = 0.02), AND TOTAL PAL (P = 0.02) PRE TO POST INTERVENTION. CONCLUSION: THIS 12-WEEK COMMUNITY-BASED YOGA INTERVENTION WAS FEASIBLE AND PROVIDES PRELIMINARY EVIDENCE FOR THE BENEFITS OF YOGA ON HRQL, PHYSICAL FITNESS AND PAL IN PEDIATRIC CANCER OUT-PATIENTS. IN A POPULATION WHERE SEDENTARY BEHAVIOR AND THE ASSOCIATED CO-MORBIDITIES ARE A GROWING CONCERN, THESE RESULTS PROMOTE THE CONTINUED EXPLORATION OF YOGA PROGRAMMING.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
14  504  38 COMMUNITY-DELIVERED HEATED HATHA YOGA AS A TREATMENT FOR DEPRESSIVE SYMPTOMS: AN UNCONTROLLED PILOT STUDY. OBJECTIVES: THERE ARE NO KNOWN STUDIES OF CONCURRENT EXPOSURE TO HIGH TEMPERATURE AND YOGA FOR THE TREATMENT OF DEPRESSION. THIS STUDY EXPLORED ACCEPTABILITY AND FEASIBILITY OF HEATED (BIKRAM) YOGA AS A TREATMENT FOR INDIVIDUALS WITH DEPRESSIVE SYMPTOMS. DESIGN: AN 8-WEEK, OPEN-LABEL PILOT STUDY OF HEATED YOGA FOR DEPRESSIVE SYMPTOMS. SUBJECTS: 28 MEDICALLY HEALTHY ADULTS (71.4% FEMALE, MEAN AGE 36 [STANDARD DEVIATION 13.57]) WITH AT LEAST MILD DEPRESSIVE SYMPTOMS (HAMILTON RATING SCALE FOR DEPRESSION [HRSD-17] SCORE >/=10) WHO ATTENDED AT LEAST ONE YOGA CLASS AND SUBSEQUENT ASSESSMENT VISIT. INTERVENTION: PARTICIPANTS WERE ASKED TO ATTEND AT LEAST TWICE WEEKLY COMMUNITY HELD BIKRAM YOGA CLASSES. ASSESSMENTS WERE PERFORMED AT SCREENING AND WEEKS 1, 3, 5, AND 8. HYPOTHESES WERE TESTED USING A MODIFIED-INTENT-TO-TREAT APPROACH, INCLUDING PARTICIPANTS WHO ATTENDED AT LEAST ONE YOGA CLASS AND SUBSEQUENT ASSESSMENT VISIT (N = 28). RESULTS: ALMOST HALF OF OUR SUBJECTS COMPLETED THE 8-WEEK INTERVENTION, AND CLOSE TO A THIRD ATTENDED THREE QUARTERS OR MORE OF THE PRESCRIBED 16 CLASSES OVER 8 WEEKS. MULTILEVEL MODELING REVEALED SIGNIFICANT IMPROVEMENTS OVER TIME IN BOTH CLINICIAN-RATED HRSD-17 (P = 0.003; DGLMM = 1.43) AND SELF-REPORTED BECK DEPRESSION INVENTORY (BDI; P < 0.001, DGLMM = 1.31) DEPRESSIVE SYMPTOMS, AS WELL AS THE FOUR SECONDARY OUTCOMES: HOPELESSNESS (P = 0.024, DGLMM = 0.57), ANXIETY (P < 0.001, DGLMM = 0.78), COGNITIVE/PHYSICAL FUNCTIONING (P < 0.001, DGLMM = 1.34), AND QUALITY OF LIFE (P = 0.007, DGLMM = 1.29). OF 23 PARTICIPANTS WITH DATA THROUGH WEEK 3 OR LATER, 12 (52.2%) WERE TREATMENT RESPONDERS (>/=50% REDUCTION IN HRSD-17 SCORE), AND 13 (56.5%) ATTAINED REMISSION (HRSD SCORE </=7). MORE FREQUENT ATTENDANCE WAS SIGNIFICANTLY ASSOCIATED WITH IMPROVEMENT IN SELF-RATED DEPRESSION SYMPTOMS, HOPELESSNESS, AND QUALITY OF LIFE. CONCLUSIONS: THE ACCEPTABILITY AND FEASIBILITY OF HEATED YOGA IN THIS PARTICULAR SAMPLE WITH THIS PROTOCOL WARRANTS FURTHER ATTENTION. THE HEATED YOGA WAS ASSOCIATED WITH REDUCED DEPRESSIVE SYMPTOMS, AND OTHER IMPROVED RELATED MENTAL HEALTH SYMPTOMS, INCLUDING ANXIETY, HOPELESSNESS, AND QUALITY OF LIFE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
15 1292  34 GROUP YOGA EFFECTS ON CANCER PATIENT AND CAREGIVER SYMPTOM DISTRESS: ASSESSMENT OF SELF-REPORTED SYMPTOMS AT A COMPREHENSIVE CANCER CENTER. BACKGROUND: COMPLEMENTARY AND INTEGRATIVE HEALTH APPROACHES SUCH AS YOGA PROVIDE SUPPORT FOR PSYCHOSOCIAL HEALTH. WE EXPLORED THE EFFECTS OF GROUP-BASED YOGA CLASSES OFFERED THROUGH AN INTEGRATIVE MEDICINE CENTER AT A COMPREHENSIVE CANCER CENTER. METHODS: PATIENTS AND CAREGIVERS HAD ACCESS TO TWO YOGA GROUP CLASSES: A LOWER INTENSITY (YLOW) OR HIGHER INTENSITY (YHIGH) CLASS. PARTICIPANTS COMPLETED THE EDMONTON SYMPTOM ASSESSMENT SYSTEM (ESAS; SCALE 0-10, 10 MOST SEVERE) IMMEDIATELY BEFORE AND AFTER THE CLASS. ESAS SUBSCALES ANALYZED INCLUDED GLOBAL (GDS; SCORE 0-90), PHYSICAL (PHS; 0-60), AND PSYCHOLOGICAL DISTRESS (PSS; 0-20). DATA WERE ANALYZED EXAMINING PRE-YOGA AND POST-YOGA SYMPTOM SCORES USING PAIRED T-TESTS AND BETWEEN TYPES OF CLASSES USING ANOVAS. RESULTS: FROM JULY 18, 2016, TO AUGUST 8, 2017, 282 UNIQUE PARTICIPANTS (205 PATIENTS, 77 CAREGIVERS; 85% FEMALE; AGES 20-79 YEARS) ATTENDED ONE OR MORE YOGA GROUPS (MEAN 2.3). FOR ALL PARTICIPANTS, WE OBSERVED CLINICALLY SIGNIFICANT REDUCTION/IMPROVEMENT IN GDS, PHS, AND PSS SCORES AND IN SYMPTOMS (ESAS DECREASE >/=1; MEANS) OF ANXIETY, FATIGUE, WELL-BEING, DEPRESSION, APPETITE, DROWSINESS, AND SLEEP. CLINICALLY SIGNIFICANT IMPROVEMENT FOR BOTH PATIENTS AND CAREGIVERS WAS OBSERVED FOR ANXIETY, DEPRESSION, FATIGUE, WELL-BEING, AND ALL ESAS SUBSCALES. COMPARING YOGA GROUPS, YLOW CONTRIBUTED TO GREATER IMPROVEMENT IN SLEEP VERSUS YHIGH (-1.33 VS -0.50, P = .054). IMPROVEMENT IN FATIGUE FOR YLOW WAS THE GREATEST MEAN CHANGE (YLOW -2.12). CONCLUSION: A SINGLE YOGA GROUP CLASS RESULTED IN CLINICALLY MEANINGFUL IMPROVEMENT OF MULTIPLE SELF-REPORTED SYMPTOMS. FURTHER RESEARCH IS NEEDED TO BETTER UNDERSTAND HOW YOGA CLASS CONTENT, INTENSITY, AND DURATION CAN AFFECT OUTCOMES.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
16 2143  45 THE EFFECTS OF M2M AND ADAPTED YOGA ON PHYSICAL AND PSYCHOSOCIAL OUTCOMES IN PEOPLE WITH MULTIPLE SCLEROSIS. OBJECTIVE: TO INVESTIGATE THE EFFECTS OF TWO 12-WEEK EXERCISE TRAINING INTERVENTIONS, MOVEMENT-TO-MUSIC (M2M) AND ADAPTED YOGA (AY), ON PHYSICAL AND PSYCHOSOCIAL OUTCOMES IN PEOPLE WITH MULTIPLE SCLEROSIS (MS). DESIGN: THREE-ARM RANDOMIZED CONTROLLED PROOF-OF-CONCEPT TRIAL. SETTING: A COMMUNITY-BASED FITNESS FACILITY. PARTICIPANTS: PARTICIPANTS (N=81) WITH MS (PATIENT DETERMINED DISEASE STEPS [PDDS] SELF-REPORTED DISEASE STATUS SCORES: 0-6) BETWEEN AGES OF 18 AND 65 YEARS WERE RANDOMIZED TO M2M (N=27), AY (N=26), OR WAITLIST CONTROL (N=28). INTERVENTIONS: BOTH M2M AND AY COMPLETED THREE 60-MINUTE EXERCISE SESSIONS PER WEEK FOR 12 WEEKS. WAITLIST CONTROLS RECEIVED BIWEEKLY NEWSLETTERS VIA MAIL THAT CONTAINED EDUCATIONAL INFORMATION ON LIVING WITH MS. MAIN OUTCOME MEASURES: PRIMARY MEASURES WERE TIMED UP AND GO (TUG, S) TEST, 6-MINUTE WALK TEST (6MWT, M), AND 5 TIMES SIT-TO-STAND TEST (FTSST, S). SECONDARY MEASURES WERE SELF-REPORTED OUTCOMES ASSESSED USING PATIENT-REPORTED OUTCOMES MEASUREMENT INFORMATION SYSTEM FATIGUE AND PAIN INTERFERENCE SHORT FORM 8A. PARTICIPANTS WERE EVALUATED AT BASELINE AND POSTINTERVENTION. PRIMARY ANALYSES WERE PERFORMED USING AN INTENT-TO-TREAT MIXED MODEL ANALYSIS OF COVARIANCE. RESULTS: COMPARISONS ACROSS ALL 3 GROUPS REVEALED SIGNIFICANT GROUP DIFFERENCES IN TUG AND 6MWT. POST HOC ANALYSES INDICATED SIGNIFICANT IMPROVEMENTS IN TUG (LEAST SQUARE MEAN DIFFERENCE [95% CONFIDENCE INTERVAL] = -1.9S [-3.3 TO -0.5], P=.01, D=0.7) AND 6MWT (41.0M [2.2-80.0], P=.04, D=0.6; CONTROLLED FOR PDDS) IN M2M COMPARED TO CONTROLS, WHILE NO SIGNIFICANT DIFFERENCES WERE OBSERVED WHEN COMPARED AY TO CONTROLS. NO SIGNIFICANT GROUP DIFFERENCES WERE FOUND IN FTSST, FATIGUE, AND PAIN INTERFERENCE. CONCLUSIONS: M2M MAY BE A USEFUL AND ENJOYABLE EXERCISE FORM FOR PEOPLE WITH MS IN IMPROVING MOBILITY AND WALKING ENDURANCE AND MERITS LONG-TERM STUDY IN LARGER STUDY POPULATIONS.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
17  594  29 DEVELOPMENT AND FEASIBILITY OF A GROUP-BASED THERAPEUTIC YOGA PROGRAM FOR WOMEN WITH CHRONIC PELVIC PAIN. OBJECTIVE: TO DEVELOP A GROUP-BASED THERAPEUTIC YOGA PROGRAM FOR WOMEN WITH CHRONIC PELVIC PAIN (CPP) AND EXPLORE THE EFFECTS OF THIS PROGRAM ON PAIN SEVERITY, SEXUAL FUNCTION, AND WELL-BEING. METHODS: A YOGA THERAPY PROGRAM FOR CPP WAS DEVELOPED BY A MULTIDISCIPLINARY PANEL OF CLINICIANS, RESEARCHERS, AND YOGA CONSULTANTS. WOMEN REPORTING MODERATE TO SEVERE PELVIC PAIN FOR AT LEAST SIX MONTHS WERE RECRUITED INTO A SINGLE-ARM TRIAL. PARTICIPANTS ATTENDED TWICE WEEKLY GROUP CLASSES FOCUSING ON IYENGAR-BASED YOGA TECHNIQUES AND WERE INSTRUCTED TO PRACTICE YOGA AT HOME AN HOUR A WEEK FOR SIX WEEKS. PARTICIPANTS SELF-RATED THE SEVERITY OF THEIR PELVIC PAIN USING DAILY LOGS. THE IMPACT OF PARTICIPANTS' PAIN ON EVERYDAY ACTIVITIES, EMOTIONAL WELL-BEING, AND SEXUAL FUNCTION WAS ASSESSED USING AN IMPACT OF PELVIC PAIN (IPP) QUESTIONNAIRE. SEXUAL FUNCTION WAS FURTHER ASSESSED USING THE SEXUAL HEALTH OUTCOMES IN WOMEN QUESTIONNAIRE (SHOW-Q). RESULTS: AMONG THE 16 PARTICIPANTS (AGE RANGE = 31-64 YEARS), AVERAGE RATINGS OF THE SEVERITY OF PAIN "AT ITS WORST," "AT ITS BEST," AND "ON AVERAGE" DECREASED BY 29%, 32%, AND 34%, RESPECTIVELY, FROM START TO SIX WEEKS (P < 0.05 FOR ALL). WOMEN DEMONSTRATED IMPROVEMENTS IN SCORES ON IPP SUBSCALES FOR DAILY ACTIVITIES (1.8 +/- 0.7 TO 0.9 +/- 0.7, P < 0.001), EMOTIONAL WELL-BEING (1.7 +/- 0.9 TO 0.9 +/- 0.7, P = 0.005), AND SEXUAL FUNCTION (1.9 +/- 1.1 TO 1.0 +/- 0.9, P = 0.04). SCORES ON THE SHOW-Q "PELVIC PROBLEM INTERFERENCE" SCALE ALSO IMPROVED OVER SIX WEEKS (53 +/- 23 TO 27 +/- 23, P = 0.002). CONCLUSIONS: FINDINGS PROVIDE PRELIMINARY EVIDENCE OF THE FEASIBILITY OF TEACHING WOMEN WITH CPP TO PRACTICE YOGA TO SELF-MANAGE PAIN AND IMPROVE QUALITY OF LIFE AND SEXUAL FUNCTION.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
18 2812  42 YOGA TO REDUCE TRAUMA-RELATED DISTRESS AND EMOTIONAL AND BEHAVIORAL DIFFICULTIES AMONG CHILDREN LIVING IN ORPHANAGES IN HAITI: A PILOT STUDY. OBJECTIVES: TO MEASURE TRAUMA-RELATED DISTRESS AND EVALUATE THE FEASIBILITY, ACCEPTABILITY, AND PRELIMINARY EFFICACY OF AN 8-WEEK YOGA INTERVENTION (YI) IN REDUCING TRAUMA-RELATED SYMPTOMS AND EMOTIONAL AND BEHAVIORAL DIFFICULTIES (EBD) AMONG CHILDREN LIVING IN ORPHANAGES IN HAITI. DESIGN: CASE COMPARISON WITH RANDOM ASSIGNMENT TO YI OR AEROBIC DANCE CONTROL (DC) PLUS A NONRANDOMIZED WAIT-LIST CONTROL (WLC) GROUP. SETTING: TWO ORPHANAGES FOR CHILDREN IN HAITI. PARTICIPANTS: 76 CHILDREN AGE 7 TO 17 YEARS. INTERVENTION: THE YI INCLUDED YOGA POSTURES, BREATHING EXERCISES, AND MEDITATION. THE DC GROUP LEARNED A SERIES OF DANCE ROUTINES. THE WLC GROUP RECEIVED SERVICES AS USUAL IN THE INSTITUTIONAL SETTING. AFTER COMPLETION OF DATA COLLECTION, THE WLC GROUP RECEIVED BOTH YOGA AND DANCE CLASSES FOR 8 WEEKS. OUTCOME MEASURES: THE UCLA PTSD REACTION INDEX AND THE STRENGTHS AND DIFFICULTIES QUESTIONNAIRE WERE USED TO INDICATE TRAUMA-RELATED SYMPTOMS AND EBD, RESPECTIVELY. A WITHIN-SUBJECT ANALYSIS WAS CONDUCTED TO COMPARE PRE- AND POST-TREATMENT SCORES. A POST-TREATMENT YOGA EXPERIENCE QUESTIONNAIRE EVALUATED ACCEPTABILITY OF THE YI. RESULTS: ANALYSES OF VARIANCE REVEALED A SIGNIFICANT EFFECT (F[2,28]=3.30; P=0.05) OF THE YI ON THE TRAUMA-RELATED SYMPTOM SCORES. REGRESSION ANALYSES SHOWED THAT PARTICIPATION IN EITHER 8 WEEKS OF YOGA OR DANCE CLASSES SUGGESTED A REDUCTION IN TRAUMA-RELATED SYMPTOMS AND EBD, ALTHOUGH THIS FINDING WAS NOT STATISTICALLY SIGNIFICANT (P>0.05). RESPONDENTS REPORTED SATISFACTION WITH THE YOGA PROGRAM AND IMPROVED WELL-BEING. CONCLUSIONS: CHILDREN WITH TRAUMA-RELATED DISTRESS SHOWED IMPROVEMENTS IN SYMPTOMS AFTER PARTICIPATION IN AN 8-WEEK YOGA PROGRAM COMPARED TO CONTROLS. YOGA IS A FEASIBLE AND ACCEPTABLE ACTIVITY WITH SELF-REPORTED BENEFITS TO CHILD MENTAL AND PHYSICAL HEALTH. ADDITIONAL RESEARCH IS NEEDED TO FURTHER EVALUATE THE EFFECT OF YOGA TO RELIEVE TRAUMA-RELATED DISTRESS AND PROMOTE WELL-BEING AMONG CHILDREN.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
19 1085  40 EFFECTS OF YOGA ON STRESS, FATIGUE, MUSCULOSKELETAL PAIN, AND THE QUALITY OF LIFE AMONG EMPLOYEES OF DIAMOND INDUSTRY: A NEW APPROACH IN EMPLOYEE WELLNESS. BACKGROUND: DIAMOND INDUSTRY EMPLOYEES OFTEN EXPERIENCE MUSCULOSKELETAL PAIN, FATIGUE, AND STRESS, CONTRIBUTING TO A LOW QUALITY OF LIFE (QOL). YOGA IS AN ANCIENT DISCIPLINE OF MIND-BODY PRACTICE YOGA HAS NUMEROUS HEALTH BENEFITS. OBJECTIVE: THIS STUDY INVESTIGATED THE EFFICACY OF WORKPLACE YOGA IN IMPROVING STRESS, MUSCULOSKELETAL PAIN, FATIGUE, AND QOL AMONG EMPLOYEES OF THE DIAMOND INDUSTRY. METHODS: ONE-HUNDRED SIXTY-SIX EMPLOYEES OF THE DIAMOND INDUSTRY BETWEEN THE AGES OF 20 AND 60 PARTICIPATED IN THE STUDY. PARTICIPANTS WERE ASSIGNED TO EITHER YOGA (N = 84) OR WAITLIST (N = 82) GROUPS. THE YOGA GROUP RECEIVED ONE HOUR OF YOGA, FOUR DAYS A WEEK FOR THREE CONSECUTIVE MONTHS. PARTICIPANTS IN THE WAITLIST GROUP FOLLOWED THEIR DAILY ROUTINES. MUSCULOSKELETAL PAIN, FATIGUE, STRESS, AND QOL WERE ASSESSED AT BASELINE AND AFTER THREE MONTHS. RESULTS: ONE-HUNDRED FIFTY-FIVE EMPLOYEES COMPLETED THE STUDY. THE YOGA GROUP SHOWED SIGNIFICANT (P < 0.05) IMPROVEMENT IN PAIN, PERCEIVED STRESS, FATIGUE, AND QOL DOMAINS AFTER THREE MONTHS COMPARED TO BASELINE. THE WAITLIST GROUP SHOWED NO SIGNIFICANT IMPROVEMENT IN ANY OF THE MEASURES. IN THE POST SCORES COMPARISON BETWEEN THE GROUPS REVEALED A SIGNIFICANT DIFFERENCE BETWEEN THE GROUPS. CONCLUSION: WORKPLACE YOGA FOUND TO BE A USEFUL, COST-EFFECTIVE AND FEASIBLE INTERVENTION IN IMPROVING STRESS, MUSCULOSKELETAL PAIN, FATIGUES AND QUALITY OF LIFE AMONG EMPLOYEES OF THE DIAMOND INDUSTRY. YOGA MAY BE IMPLEMENTED IN THE WORKPLACE AS A WELLNESS PROGRAM AT THE WORKPLACE.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
20 1034  46 EFFECTS OF YOGA IN DAILY LIFE PROGRAM IN RHEUMATOID ARTHRITIS: A RANDOMIZED CONTROLLED TRIAL. OBJECTIVES: TO EXPLORE THE FEASIBILITY AND EFFECTIVENESS OF A YOGA PROGRAM IN IMPROVING HEALTH-RELATED QUALITY OF LIFE (HQOL), PHYSICAL AND PSYCHOLOGICAL FUNCTIONING IN RHEUMATOID ARTHRITIS (RA) PATIENTS. DESIGN: SINGLE-CENTRE PARALLEL-ARMS RANDOMIZED CONTROLLED TRIAL COMPARING YOGA (N = 30) AND EDUCATION CONTROL GROUP (N = 27). SETTING: TERTIARY CARE UNIVERSITY HOSPITAL. INTERVENTION: A 12-WEEK YOGA PROGRAM, BASED ON THE YOGA IN DAILY LIFE SYSTEM, INCLUDED 2X WEEKLY/90-MINUTE SESSIONS. THE CONTROL GROUP HAD 1XWEEKLY/60-MINUTE EDUCATIONAL LECTURES ON ARTHRITIS-RELATED TOPICS. MAIN OUTCOME MEASURES: ASSESSMENTS WERE PERFORMED AT BASELINE, 12 (POST-INTERVENTION) AND 24 WEEKS (FOLLOW-UP). THE PRIMARY OUTCOME WAS CHANGE IN THE SHORT FORM-36 (SF-36) HQOL AT 12 WEEKS. LINEAR REGRESSION ANALYSIS WAS ADJUSTED FOR BASELINE SCORES. RESULTS: NO SIGNIFICANT BETWEEN-GROUP DIFFERENCES WERE FOUND FOR SF-36 (ALL P > 0.05). AT 12 WEEKS THE ADJUSTED MEAN DIFFERENCE BETWEEN GROUPS FAVOURED YOGA FOR FUNCTIONAL ASSESSMENT OF CHRONIC ILLNESS THERAPY-FATIGUE (5.08 CI 1.29 TO 8.86; P = 0.009) AND HOSPITAL ANXIETY AND DEPRESSION SCALE (HADS)-DEPRESSION (-1.37 CI -2.38 TO -0.36); P = 0.008) AND AT 24 WEEKS FOR HADS-ANXIETY (-1.79 CI -3.34 TO - 0.23; P = 0.025), WHILE THE IMPACT ON FATIGUE WAS SUSTAINED (5.43 CI 1.33 TO 9.54, P = 0.01). THE PROGRAM HAD NO IMPACT ON RA DISEASE ACTIVITY. FEASIBILITY OUTCOMES INCLUDED RECRUITMENT RATE 16 %, RETENTION 80.7 %, AND ADHERENCE TO YOGA 87.5 VS 82.7 % FOR CONTROL. NO SERIOUS ADVERSE EVENTS WERE RECORDED. CONCLUSIONS: YOGA IN DAILY LIFE PROGRAM WAS NOT ASSOCIATED WITH CHANGE IN HEALTH-RELATED QUALITY OF LIFE OF RA PATIENTS. SIGNIFICANT IMPROVEMENTS IN FATIGUE AND MOOD WERE OBSERVED AT POSTINTERVENTION AND FOLLOW-UP. THIS YOGA PROGRAM WAS FOUND FEASIBLE AND SAFE FOR PATIENTS AND MAY COMPLEMENT STANDARD RA TREAT-TO-TARGET STRATEGY.	2021