1  109 134 A PILOT STUDY ASSESSING ACCEPTABILITY AND FEASIBILITY OF HATHA YOGA FOR CHRONIC PAIN IN PEOPLE RECEIVING OPIOID AGONIST THERAPY FOR OPIOID USE DISORDER. THE PURPOSE OF THIS PROJECT WAS TO ASSESS THE FEASIBILITY AND ACCEPTABILITY OF A HATHA YOGA PROGRAM DESIGNED TO TARGET CHRONIC PAIN IN PEOPLE RECEIVING OPIOID AGONIST THERAPY FOR OPIOID USE DISORDER. WE CONDUCTED A PILOT RANDOMIZED TRIAL IN WHICH PEOPLE WITH CHRONIC PAIN WHO WERE RECEIVING EITHER METHADONE MAINTENANCE THERAPY (N=20) OR BUPRENORPHINE (N=20) WERE RANDOMLY ASSIGNED TO WEEKLY HATHA YOGA OR HEALTH EDUCATION (HE) CLASSES FOR 3MONTHS. WE DEMONSTRATED FEASIBILITY IN MANY DOMAINS, INCLUDING RECRUITMENT OF PARTICIPANTS (58% FEMALE, MEAN AGE 43), RETENTION FOR FOLLOW-UP ASSESSMENTS, AND ABILITY OF TEACHERS TO PROVIDE INTERVENTIONS WITH HIGH FIDELITY TO THE MANUALS. FIFTY PERCENT OF PARTICIPANTS IN YOGA (95% CI: 0.28-0.72) AND 65% OF PARTICIPANTS IN HE (95% CI: 0.44-0.87) ATTENDED AT LEAST 6 OF 12 POSSIBLE CLASSES (P=0.62). SIXTY-ONE PERCENT IN THE YOGA GROUP REPORTED PRACTICING YOGA AT HOME, WITH A MEAN NUMBER OF TIMES PRACTICING PER WEEK OF 2.67 (SD=2.37). PARTICIPANT MOOD IMPROVED PRE-CLASS TO POST-CLASS, WITH GREATER DECREASES IN ANXIETY AND PAIN FOR THOSE IN THE YOGA GROUP (P<0.05). IN CONCLUSION, YOGA CAN BE DELIVERED ON-SITE AT OPIOID AGONIST TREATMENT PROGRAMS WITH HOME PRACTICE TAKEN UP BY THE MAJORITY OF PARTICIPANTS. FUTURE RESEARCH MAY EXPLORE WAYS OF INCREASING THE YOGA "DOSAGE" RECEIVED. THIS MAY INVOLVE TESTING STRATEGIES FOR INCREASING EITHER CLASS ATTENDANCE OR THE AMOUNT OF HOME PRACTICE OR BOTH.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
2 1242  49 FEASIBILITY OF A YOGA INTERVENTION TO DECREASE PAIN IN OLDER WOMEN: A RANDOMIZED CONTROLLED PILOT STUDY. BACKGROUND: A SIGNIFICANT PROPORTION OF OLDER WOMEN SUFFER FROM CHRONIC PAIN, WHICH CAN DECREASE QUALITY OF LIFE. THE OBJECTIVE OF THIS PILOT RANDOMIZED STUDY WAS TO EVALUATE THE FEASIBILITY OF A FLOW-RESTORATIVE YOGA INTERVENTION DESIGNED TO DECREASE PAIN AND RELATED OUTCOMES AMONG WOMEN AGED 60 OR OLDER. METHODS: FLOW-RESTORATIVE YOGA CLASSES WERE HELD TWICE WEEKLY FOR 1 HOUR AND LED BY A CERTIFIED YOGA INSTRUCTOR. PARTICIPANTS RANDOMIZED TO THE INTERVENTION GROUP ATTENDED THE YOGA CLASSES FOR 12 WEEKS AND RECEIVED SUPPLEMENTAL MATERIALS FOR AT-HOME PRACTICE. THOSE RANDOMIZED TO THE CONTROL GROUP WERE ASKED TO MAINTAIN THEIR NORMAL DAILY ROUTINE. FEASIBILITY WAS EVALUATED USING RECRUITMENT AND RETENTION RATES, CLASS AND HOME PRACTICE ADHERENCE RATES, AND PARTICIPANT SATISFACTION SURVEYS. OUTCOME MEASURES (SELF-REPORTED PAIN, INFLAMMATORY MARKERS, FUNCTIONAL FITNESS, QUALITY OF LIFE, RESILIENCE, AND SELF-REPORTED PHYSICAL ACTIVITY) WERE ASSESSED AT BASELINE AND POST-INTERVENTION. PAIRED T-TESTS OR WILCOXON SIGNED-RANK TESTS WERE USED TO EXAMINE CHANGES IN OUTCOME MEASURES WITHIN TREATMENT GROUPS. RESULTS: THIRTY-EIGHT PARTICIPANTS WERE RECRUITED AND RANDOMIZED. PARTICIPANTS WERE PRIMARILY WHITE, COLLEGE-EDUCATED, AND HIGHER FUNCTIONING, DESPITE EXPERIENCING VARIOUS FORMS OF CHRONIC PAIN. ATTENDANCE AND RETENTION RATES WERE HIGH (91 AND 97%, RESPECTIVELY) AND THE MAJORITY OF PARTICIPANTS WERE SATISFIED WITH THE YOGA PROGRAM (89%) AND WOULD RECOMMEND IT TO OTHERS (87%). INTERVENTION PARTICIPANTS ALSO EXPERIENCED REDUCTIONS IN PAIN INTERFERENCE AND IMPROVEMENTS IN ENERGY AND SOCIAL FUNCTIONING. CONCLUSIONS: THIS PILOT STUDY PROVIDES ESSENTIAL DATA TO INFORM A FULL SCALE RANDOMIZED TRIAL OF FLOW-RESTORATIVE YOGA FOR OLDER WOMEN WITH CHRONIC PAIN. FUTURE STUDIES SHOULD EMPHASIZE STRATEGIES TO RECRUIT A MORE DIVERSE STUDY POPULATION, PARTICULARLY OLDER WOMEN AT HIGHER RISK OF DISABILITY AND FUNCTIONAL DECLINE. TRIAL REGISTRATION: CLINICALTRIALS.GOV , NCT03790098 . REGISTERED 31 DECEMBER 2018 - RETROSPECTIVELY REGISTERED.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
3  622  45 DEVELOPMENT, VALIDATION, AND FEASIBILITY TESTING OF A YOGA MODULE FOR OPIOID USE DISORDER. CONTEXT: OPIOID USE DISORDER (OUD) INVOLVES EXCESSIVE USE OF OPIOIDS-SUCH AS HEROIN, MORPHINE, FENTANYL, CODEINE, OXYCODONE, AND HYDROCODONE-LEADING TO MAJOR HEALTH, SOCIAL, AND ECONOMIC CONSEQUENCES. YOGA LIFESTYLE INTERVENTIONS HAVE BEEN FOUND TO BE USEFUL AS ADJUNCT THERAPIES IN MANAGEMENT OF SUBSTANCE USE DISORDERS AND CHRONIC PAIN CONDITIONS. OBJECTIVE: THE RESEARCH TEAM INTENDED TO DEVELOP, VALIDATE, AND TEST FOR FEASIBILITY A YOGA PROGRAM FOR OUD PATIENTS THAT COULD REDUCE OPIATE WITHDRAWAL SYMPTOMS-SUCH AS PAIN, FATIGUE, LOW MOOD, ANXIETY AND SLEEP DISTURBANCES-AND CRAVINGS ASSOCIATED WITH DRUGS. DESIGN: THE RESEARCH TEAM FIRST PERFORMED A LITERATURE REVIEW OF TRADITIONAL AND CONTEMPORARY YOGA TEXTS, SUCH AS HATHA YOGA PRADIPIKA AND LIGHT ON YOGA, AS WELL AS MODERN SCIENTIFIC LITERATURE IN THE FOLLOWING SEARCH ENGINES-GOOGLE SCHOLAR, PUBMED, AND PSYCHINFO, USING THE KEYWORDS YOGA, PRANAYAMA, HATHA YOGA, RELAXATION. MEDITATION, SUBSTANCE USE, ADDICTION, IMPULSIVITY, CRAVING, SLEEP QUALITY, AND FATIGUE. USING THE INFORMATION OBTAINED, THE TEAM DEVELOPED A YOGA PROGRAM AND DESIGNED A PILOT STUDY THAT USED THE PROGRAM. SETTING: THE STUDY TOOK PLACE IN THE DEPARTMENT OF INTEGRATIVE MEDICINE AT THE NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES (NIMHANS) IN BANGALORE, INDIA. PARTICIPANTS: PARTICIPANTS IN THE PILOT STUDY WERE 8 INPATIENTS, 6 MALES AND 2 FEMALES, WHO WERE ON OPIOID AGONIST TREATMENT (BUPRENORPHINE) FOR OUD. INTERVENTION: THE INTERVENTION WAS THE YOGA PROGRAM PREVIOUSLY VALIDATED BY THE RESEARCH TEAM. IN THE PILOT STUDY, PARTICIPANTS WERE TAUGHT A ONE-HOUR, YOGA-BASED INTERVENTION, WITH SESSIONS OCCURRING ONCE PER DAY, FOR 10 SESSIONS. OUTCOME MEASURES: FOR VALIDATION, 13 EXPERTS SCORED THE YOGA PROGRAM THAT THE RESEARCH TEAM HAD DEVELOPED AND GAVE SUGGESTIONS FOR EACH YOGIC PRACTICE FOR USE DURING THE ACUTE PHASE OF WITHDRAWAL AND THE MAINTENANCE PHASE RESPECTIVELY. A CONTENT VALIDITY RATIO (CVR) WAS CALCULATED FROM THEIR SCORING, AND THE RESEARCH TEAM MADE CHANGES TO THE PROGRAM BASE ON THE SCORING AND SUGGESTIONS. FOR THE PILOT STUDY, ASSESSMENTS OCCURRED AT BASELINE AND POSTINTERVENTION. THE PARTICIPANTS' YOGA PERFORMANCE WAS RATED BY THE YOGA TRAINER ON A YOGA PERFORMANCE ASSESSMENT SCALE (YPA). OTHER MEASUREMENTS INCLUDED: (1) THE CLINICAL OPIATE WITHDRAWAL SCALE (COWS), (2) THE HAMILTON'S ANXIETY RATING SCALE (HAM-A), (3) THE HAMILTON'S DEPRESSION RATING SCALE (HAM-D), (4) BUPRENORPHINE DOSAGE, (5) THE CLINICAL GLOBAL IMPRESSION SEVERITY (CGI-S) SCALE, (6) A VISUAL ANALOG SCALE (VAS) FOR PAIN, (7) SLEEP QUALITY (LATENCY AND DURATION), AND (8) THE MODULE'S SAFETY. RESULTS: FOUR PRACTICES WERE REMOVED FROM THE PROGRAM DUE TO CVR SCORES BELOW THE CUTOFF, AND ONE PRACTICE WAS FOUND NOT TO BE FEASIBLE (KAPALABHATI). TWO CATEGORIES OF YOGA MODULES EMERGED: (1) FOR THE ACUTE SYMPTOMATIC PHASE (40 MINUTES) AND (2) FOR THE MAINTENANCE PHASE (ONE HOUR). PRACTICES WERE ADDED OR EXCLUDED BASED ON THE PHASE. CONCLUSIONS: THE YOGA MODULE THAT WAS DEVELOPED FOR REDUCING WITHDRAWAL SYMPTOMS AND CRAVINGS IN OUD PATIENTS WAS FOUND TO BE SAFE, FEASIBLE, AND POTENTIALLY USEFUL AS AN ADJUNCT THERAPY TO CONVENTIONAL TREATMENT.	2021	

4 2579  24 YOGA FOR HEALTH-RELATED QUALITY OF LIFE IN ADULT CANCER: A RANDOMIZED CONTROLLED FEASIBILITY STUDY. AN INCREASE IN PATIENT-LED UPTAKE OF COMPLEMENTARY THERAPIES IN ADULT CANCER HAS LED TO A NEED FOR MORE RIGOROUS STUDY OF SUCH INTERVENTIONS AND THEIR OUTCOMES. THIS STUDY THEREFORE AIMED TO EVALUATE THE FEASIBILITY AND ACCEPTABILITY OF A YOGA INTERVENTION IN MEN AND WOMEN RECEIVING CONVENTIONAL TREATMENT FOR A CANCER DIAGNOSIS. PROSPECTIVE, MIXED METHODS FEASIBILITY TRIAL ALLOCATED PARTICIPANTS TO RECEIVE ONE OF THREE YOGA INTERVENTIONS OVER A FOUR-WEEK STUDY PERIOD. DATA COLLECTION WAS COMPLETED THROUGH ONLINE SURVEY OF QOL-CA/CS AND CUSTOMIZED SURVEYS. FIFTEEN PARTICIPANTS WERE INCLUDED (11 FEMALE) UNDERGOING TREATMENT FOR BREAST, PROSTATE, COLORECTAL, BRAIN, AND BLOOD AND LUNG CANCER. TWO PARTICIPANTS DROPPED OUT AND COMPLETE QUALITATIVE AND QUANTITATIVE DATA SETS WERE COLLECTED FROM 12 PARTICIPANTS AND FOUR YOGA INSTRUCTORS. OTHER OUTCOME MEASURES INCLUDED IMPLEMENTATION COSTS PATIENT-REPORTED PREFERENCES FOR YOGA INTERVENTION AND CHANGES IN QOL-CA/CS. THREE TYPES OF YOGA INTERVENTION WERE SAFELY ADMINISTERED IN ADULT CANCER. MIXED METHODS, COST-EFFICIENCY, QOL-CA/CS, AND EVIDENCE-BASED DESIGN OF YOGA INTERVENTION HAVE BEEN USED TO ESTABLISH FEASIBILITY AND PATIENT-PREFERENCES FOR YOGA DELIVERY IN ADULT CANER. RESULTS SUGGEST THAT, WITH SOME METHODOLOGICAL IMPROVEMENTS, A LARGE-SCALE RANDOMIZED CONTROLLED TRIAL IS WARRANTED TO TEST THE EFFICACY OF YOGA FOR MALE AND FEMALE CANCER PATIENTS. THIS TRIAL IS REGISTERED WITH CLINICALTRIALS.GOV NCT02309112.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
5 1233  38 FEASIBILITY AND PRELIMINARY EFFICACY OF TAILORED YOGA IN SURVIVORS OF HEAD AND NECK CANCER: A PILOT STUDY. PURPOSE: TREATMENT FOR HEAD AND NECK CANCER (HNC) RESULTS IN LONG-TERM TOXICITIES AND INCREASED PHYSICAL AND PSYCHOSOCIAL SURVIVOR BURDEN. THERE ARE A LIMITED NUMBER OF TREATMENTS FOR THESE LATE EFFECTS. YOGA POSTURES, BREATH WORK, RELAXATION, AND MEDITATION, MAY IMPROVE THESE LATE EFFECTS. THE PURPOSE OF THIS STUDY WAS TO EXAMINE THE FEASIBILITY OF A TAILORED YOGA PROGRAM IN HNC SURVIVORS AND OBTAIN PRELIMINARY EFFICACY DATA. METHODS: THIS WAS A RANDOMIZED WAIT-LIST CONTROL STUDY OF YOGA-NAIVE HNC SURVIVORS WHO WERE >3 MONTHS POST-CANCER TREATMENT. BASELINE DATA WERE COLLECTED. PARTICIPANTS WERE RANDOMIZED TO EITHER AN 8-WEEK HATHA YOGA INTERVENTION GROUP OR A WAIT-LIST GROUP. FEASIBILITY AND EFFICACY DATA WERE COLLECTED. AT 4 AND 8 WEEKS, PATIENTS UNDERWENT A REPEAT ASSESSMENT OF HEALTH. WAIT-LIST CONTROL GROUP PARTICIPANTS WERE OFFERED THE YOGA PROGRAM AFTER DATA COLLECTION. DESCRIPTIVE STATISTICS EVALUATED FEASIBILITY. MIXED EFFECTS GENERAL LINEAR MODELS WERE USED TO GENERATE ESTIMATES OF THE EFFICACY OUTCOMES. RESULTS: SEVENTY-THREE INDIVIDUALS WERE SCREENED AND 40 WERE ELIGIBLE. ALL ELIGIBLE INDIVIDUALS CONSENTED AND ENROLLED. FIVE OF THE INTERVENTION GROUP DISCONTINUED EARLY AND NONE IN THE WAIT-LIST CONTROL GROUP. FEASIBILITY WAS AFFIRMED AS PARTICIPANTS WERE RECRUITED AND RETAINED IN THE STUDY, THERE WERE NO ADVERSE EVENTS, FIDELITY TO PROTOCOL WAS DEMONSTRATED, AND SATISFACTION RATES WERE HIGH. EFFICACY MEASURES INDICATED POTENTIAL BENEFIT FOR SHOULDER RANGE OF MOTION ( D = 0.57-0.86, P < .05), PAIN ( D = 0.67-0.90, P </= .005), AND ANXIETY ( D = 0.59, P = .015). CONCLUSION: A TAILORED HATHA YOGA PROGRAM IS FEASIBLE AND POTENTIALLY EFFICACIOUS FOR HNC SURVIVORS. PRELIMINARY DATA SUPPORTS FURTHER INVESTIGATION OF YOGA IN THIS POPULATION IS NEEDED.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
6 2477  39 YOGA AS AN ADJUNCTIVE INTERVENTION TO MEDICATION-ASSISTED TREATMENT WITH BUPRENORPHINE+NALOXONE. OBJECTIVE: ACCORDING TO THE CDC, 2.6 MILLION PEOPLE IN THE UNITED STATES HAVE AN OPIOID USE DISORDER AND DRUG OVERDOSE IS THE LEADING CAUSE OF ACCIDENTAL DEATH. OPIOIDS ARE INVOLVED IN 63% OF OVERDOSE DEATHS. IT IS IMPERATIVE THAT WE IDENTIFY EVIDENCE BASED TREATMENTS TO STEM THE TIDE OF THIS EPIDEMIC. THIS PILOT STUDY SERVES TO EXPLORE THE FEASIBILITY AND EFFECTIVENESS OF YOGA AS AN ADJUNCTIVE INTERVENTION FOR INDIVIDUALS WITH OPIOID USE DISORDER IN ACTIVE MEDICATION-ASSISTED TREATMENT (MAT). METHODS: PARTICIPANTS (N=26) WERE RECRUITED FROM A BUPRENORPHINE/NALOXONE MAT PROGRAM TO PARTICIPATE IN THIS STUDY. 13 PARTICIPANTS ENGAGED IN A 12 WEEK ADJUNCTIVE YOGA INTERVENTION WHILE REMAINING IN TREATMENT AS USUAL (TAU) MAT. 13 MATCHED CONTROLS WERE RECRUITED AND REMAINED IN TAU MAT. BOTH GROUPS WERE EVALUATED AT BASELINE, 45 DAYS AND 90 DAYS FOR CHANGES IN CRAVING FOR OPIOIDS, TREATMENT RETENTION, RELAPSE RATES, SLEEP, AND SYMPTOMS OF ANXIETY AND PERCEIVED STRESS. RESULTS: A TWO-WAY TREATMENT BY TIME ANALYSIS OF VARIANCE WAS PERFORMED USING A MIXED EFFECTS MODEL. THE TREATMENT BY FOLLOW-UP TIME INTERACTION EFFECT WAS SIGNIFICANT FOR PERCEIVED STRESS (P=0.026) INDICATING THAT THE YOGA INTERVENTION HAD A LARGER EFFECT THAN TAU (MAT). CHANGES IN PERCEIVED STRESS DECREASED SIGNIFICANTLY OVER TIME IN BOTH THE YOGA INTERVENTION GROUP AND THE TAU MAT MATCHED CONTROL GROUP. CONCLUSION: THIS PILOT STUDY INDICATED STRONG EVIDENCE FOR YOGA BEING AN EFFECTIVE ADJUNCTIVE TREATMENT TO MAT TAU IN REDUCING PERCEIVED STRESS. FURTHER RESEARCH WITH A LARGER POPULATION IS NEEDED TO DETERMINE IMPACT ON OTHER MENTAL HEALTH SYMPTOMS AND RELAPSE AND RETENTION RATES.	2018	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
7  719  33 EFFECT OF IYENGAR YOGA ON MENTAL HEALTH OF INCARCERATED WOMEN: A FEASIBILITY STUDY. BACKGROUND: INCARCERATED WOMEN SHARE A DISPROPORTIONATE BURDEN OF MENTAL ILLNESS. ALTHOUGH PSYCHOTROPIC MEDICATIONS ARE AVAILABLE TO WOMEN IN PRISON, ADJUNCTIVE TREATMENT MODALITIES, SUCH AS IYENGAR YOGA, MAY INCREASE PSYCHOLOGICAL WELL-BEING. OBJECTIVES: THE PURPOSES OF THIS STUDY WERE (A) TO ADDRESS THE FEASIBILITY OF PROVIDING A GENDER-RESPONSIVE EXERCISE INTERVENTION WITHIN A CORRECTIONAL INSTITUTION AND (B) TO OBSERVE THE EFFECT OF A GROUP-FORMAT IYENGAR YOGA PROGRAM THAT MET TWO SESSIONS A WEEK FOR 12 WEEKS ON LEVELS OF DEPRESSION SYMPTOMS, ANXIETY SYMPTOMS, AND PERCEIVED STRESS AMONG INCARCERATED WOMEN. METHODS: A REPEATED MEASURES DESIGN, IN WHICH EACH PARTICIPANT SERVED AS HER OWN CONTROL, WAS USED. PARTICIPANTS COMPLETED THREE SELF-ADMINISTERED INSTRUMENTS: THE BECK DEPRESSION INVENTORY, THE BECK ANXIETY INVENTORY, AND THE PERCEIVED STRESS SCALE BEFORE TREATMENT (BASELINE) AND DURING TREATMENT (WEEKS 4, 8, AND 12). LINEAR MIXED EFFECTS MODELS WERE USED TO EXAMINE STATISTICALLY SIGNIFICANT CHANGES IN MENTAL HEALTH MEASURES OVER TIME, TAKING ADVANTAGE OF ALL AVAILABLE DATA. RESULTS: ALTHOUGH 21 WOMEN INITIALLY PARTICIPATED IN THE INTERVENTION, 6 WOMEN COMPLETED THE 12-WEEK INTERVENTION. A SIGNIFICANT LINEAR DECREASE WAS DEMONSTRATED IN SYMPTOMS OF DEPRESSION OVER TIME, WITH MEAN VALUES CHANGING FROM 24.90 AT BASELINE TO 5.67 AT WEEK 12. THERE WAS A MARGINALLY SIGNIFICANT DECREASE IN ANXIETY OVER TIME (12.00 AT BASELINE TO 7.33 AT WEEK 12) AND A NONLINEAR CHANGE IN STRESS OVER TIME, WITH DECREASES FROM BASELINE TO WEEK 4 AND SUBSEQUENT INCREASES TO WEEK 12. DISCUSSION: WOMEN WHO PARTICIPATED IN THIS PROGRAM EXPERIENCED FEWER SYMPTOMS OF DEPRESSION AND ANXIETY OVER TIME. FINDINGS FROM THIS STUDY MAY BE USED TO IMPROVE FUTURE INTERVENTIONS FOCUSING ON THE HEALTH OUTCOMES OF INCARCERATED WOMEN.	2010	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
8 1248  35 FEASIBILITY OF YOGA TO IMPROVE SYMPTOMS IN INDIVIDUALS WITH SEVERE, CHRONIC TRAUMATIC BRAIN INJURY: A MIXED-METHODS CASE SERIES. CONTEXT: PEOPLE WITH SEVERE TRAUMATIC BRAIN INJURY (TBI) EXPERIENCE LIFELONG SEQUELAE THAT AFFECT PHYSICAL, COGNITIVE, AND MENTAL HEALTH. IN OTHER POPULATIONS, YOGA HAS SHOWN POTENTIAL TO ALLEVIATE INSOMNIA, PAIN, AND DEPRESSION AND TO IMPROVE COGNITION. OBJECTIVE: THE STUDY INTENDED TO INVESTIGATE THE FEASIBILITY OF A SIX-WEEK, GROUP-YOGA INTERVENTION FOR ADULTS WITH SEVERE CHRONIC TBI, FOCUSING ON SLEEP, PAIN, MOOD, AND EXECUTIVE FUNCTION. DESIGN: THE RESEARCH TEAM PERFORMED A FEASIBILITY STUDY USING A MIXED-METHODS, CASE-SERIES DESIGN. SETTING: THE STUDY RECRUITED PARTICIPANTS BY DISTRIBUTING FLYERS TO LOCAL COMMUNITIES AND TBI SUPPORT GROUPS. PARTICIPANTS: PARTICIPANTS WERE TWO PEOPLE WITH SEVERE, CHRONIC, TBI. INTERVENTION: THE INTERVENTION WAS A SIX-WEEK COURSE OF GROUP YOGA, WITH 70-MINUTE CLASSES TWICE A WEEK. OUTCOME MEASURES: THE STUDY ASSESSED OUTCOMES AT BASELINE AND POSTINTERVENTION USING VALIDATED MEASURES TO ASSESS EXECUTIVE FUNCTION, MOOD, SLEEP, AND PAIN: THE BEHAVIOR RATING INVENTORY OF EXECUTIVE FUNCTION-ADULT VERSION (BRIEF-A), BECK DEPRESSION INVENTORY (BDI), PITTSBURGH SLEEP QUALITY INDEX (PSQI), AND NEUROPATHIC PAIN SCALE (NPS). A SEMISTRUCTURED INTERVIEW WAS CONDUCTED DURING THE WEEK POSTINTERVENTION TO OBTAIN QUALITATIVE DATA. RESULTS: THE STUDY HAD A 100% RETENTION RATE, A 91.67% ATTENDANCE RATE, AND HIGH SATISFACTION. ONE PARTICIPANT DEMONSTRATED IMPROVEMENT IN ALL OUTCOMES, WHILE THE OTHER SHOWED MIXED RESULTS. DEPRESSION SHOWED THE MOST CONSISTENT IMPROVEMENT, 47.2% ON AVERAGE. FOR INSOMNIA, ONE PARTICIPANT SHOWED IMPROVED SLEEP AT 14.29%. THE QUALITATIVE DATA DEMONSTRATED POSITIVE CHANGES IN COGNITION, MOOD, SLEEP, AND PAIN. CONCLUSIONS: A SIX-WEEK GROUP YOGA INTERVENTION IS FEASIBLE AND APPEARS TO BE BENEFICIAL IN ALLEVIATING SYMPTOMS, ESPECIALLY DEPRESSION AND INSOMNIA, IN PEOPLE WITH SEVERE CHRONIC TBI. A LONGER INTERVENTION PERIOD WAS SUGGESTED BY THE PARTICIPANTS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
9  348  33 ASSESSING THE ACCEPTABILITY OF YOGA AMONG PATIENTS WITH AND WITHOUT CHRONIC PAIN ENROLLED IN A LICENSED OPIOID TREATMENT PROGRAM. THERE IS A PRESSING NEED TO IDENTIFY NON-OPIOID, EVIDENCE-BASED TREATMENTS TO ADDRESS THE HIGH PREVALENCE OF CHRONIC PAIN IN LICENSED OPIOID TREATMENT PROGRAMS (OTP). YOGA IS AN EFFECTIVE PAIN COPING STRATEGY BUT IS NOT WIDELY USED BY OTP PATIENTS. FEW STUDIES HAVE EXAMINED UNDERLYING FACTORS RELATED TO POOR YOGA UTILIZATION IN THIS POPULATION. SEVENTY-ONE PARTICIPANTS WITH AND WITHOUT CHRONIC PAIN ENROLLED IN A HOSPITAL-BASED OTP COMPLETED AN ACCEPTABILITY SURVEY ASSESSING PAIN, CURRENT PAIN COPING STRATEGIES, PRIOR YOGA EXPERIENCE, WILLINGNESS TO TRY YOGA, AND BELIEFS ABOUT YOGA. PARTICIPANTS WITH AND WITHOUT CHRONIC PAIN WERE COMPARED, AS WERE PARTICIPANTS WITH AND WITHOUT PRIOR YOGA EXPERIENCE. THE RELATIONSHIPS BETWEEN PRIMARY STUDY VARIABLES IN THE CHRONIC PAIN GROUP WERE ALSO EXPLORED. PARTICIPANTS REPORTED USING OVER-THE-COUNTER MEDICATIONS, MEDITATION, STRETCHING, AND EXERCISE TO MANAGE CHRONIC PAIN, BUT YOGA WAS NOT COMMONLY USED. PARTICIPANTS WITH PRIOR YOGA EXPERIENCE REPORTED HIGHER WILLINGNESS TO TRY YOGA AND MORE FAVORABLE BELIEFS ABOUT YOGA THAN PARTICIPANTS WITHOUT PRIOR YOGA EXPERIENCE. THERE WERE NO SIGNIFICANT DIFFERENCES IN WILLINGNESS TO TRY YOGA BETWEEN PARTICIPANTS WITH AND WITHOUT CHRONIC PAIN. AMONG PARTICIPANTS WITH CHRONIC PAIN, THERE WAS A POSITIVE ASSOCIATION BETWEEN TOTAL NUMBER OF PAIN COPING STRATEGIES USED AND WILLINGNESS TO TRY YOGA. THIS STUDY ADDS TO THE EXISTING LITERATURE ON THE IMPLEMENTATION OF YOGA PROGRAMS INTO OTPS BY DEMONSTRATING THE ACCEPTABILITY OF YOGA IN PATIENTS WITH OPIOID USE DISORDER, INCLUDING THOSE EXPERIENCING CHRONIC PAIN, AND ENCOURAGES ADDITIONAL RESEARCH EXPLORING IMPLEMENTATION.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
10 1249  40 FEASIBILITY STUDY OF A MODIFIED YOGA PROGRAM FOR CHRONIC PAIN AMONG ELDERLY ADULTS IN ASSISTED AND INDEPENDENT LIVING. CONTEXT: YOGA IMPROVES QUALITY OF LIFE IN ELDERS >/=65 YEARS, BUT STUDIES AMONG ELDERS WITH CHRONIC PAIN ARE LIMITED. OBJECTIVE: CONDUCT A FEASIBILITY STUDY OF GENTLE YOGA AMONG ELDERS IN ASSISTED AND INDEPENDENT LIVING. DESIGN: SINGLE ARM PRE/POST CLINICAL TRIAL. SUBJECTS: ADULTS (>/=65 YEARS OF AGE) WITH SELF-IDENTIFIED CHRONIC PAIN (>/=3 ON A 10-POINT SCALE, LASTING FOR >/=3 MONTHS) AND NO CURRENT YOGA PRACTICE. INTERVENTION: TEN WEEKLY 60-MIN GENTLE YOGA CLASSES TAILORED TO ELDERLY ADULTS. OUTCOME MEASURES: AT BASELINE, WEEKS 5, 10 (END OF INTERVENTION), AND 20 (FOLLOW-UP), WE COLLECTED DATA ON FEASIBILITY (ADHERENCE, RETENTION, SAFETY), PAIN, ANXIETY, DEPRESSION, FATIGUE, SLEEP DISTURBANCE, AND PHYSICAL FUNCTION. RESULTS: TWENTY-SIX PARTICIPANTS ENROLLED (88% WOMEN, 77% WHITE, 58% IN ASSISTED LIVING) WITH AVERAGE AGE OF 86.6 +/- 4.4 (MEAN, STD). TWENTY PARTICIPANTS COMPLETED THE INTERVENTION, WITH 90% ADHERING (COMPLETING >/=6 CLASSES). NINE PARTICIPANTS (45% OF COMPLETERS) EXPERIENCED ADVERSE EVENTS, WHICH WERE NON-SERIOUS AND RELATED TO TRANSIENT MUSCULOSKELETAL PAIN. NO ADVERSE EVENTS RESULTED IN STUDY WITHDRAWAL. PARTICIPANTS REPORTED BEING SOMEWHAT LIKELY TO RECOMMEND YOGA TO A FRIEND, AND QUITE A BIT LIKELY TO DO YOGA AGAIN. AT THE END OF THE INTERVENTION, FOUR OF TWENTY PARTICIPANTS REPORTED PRACTICING YOGA OUTSIDE OF CLASS. ANXIETY SIGNIFICANTLY DECREASED FROM 5.80 (SE=0.90) TO 4.44 (SE=0.74) (P = 0.014), BUT THERE WERE NO CHANGES IN OTHER MEASURES. CONCLUSIONS: OUR PILOT 10-WEEK YOGA STUDY WAS GENERALLY SAFE FOR AND SUITABLE TO ASSISTED AND INDEPENDENT LIVING ELDERLY ADULTS. FUTURE STUDIES ARE NEEDED TO EXAMINE OTHER EFFECTS OF YOGA IN ASSISTED/INDEPENDENT LIVING ADULTS WITH CHRONIC PAIN.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
11 2613  32 YOGA FOR RISK REDUCTION OF METABOLIC SYNDROME: PATIENT-REPORTED OUTCOMES FROM A RANDOMIZED CONTROLLED PILOT STUDY. LIFESTYLE CHANGE IS RECOMMENDED AS TREATMENT FOR ADULTS AT RISK FOR METABOLIC SYNDROME (METS), ALTHOUGH ADOPTION OF NEW BEHAVIORAL PATTERNS IS LIMITED. IN ADDITION, MOST EXISTING LIFESTYLE INTERVENTIONS DO NOT ADDRESS PSYCHOLOGICAL STRESS OR QUALITY OF LIFE, BOTH OF WHICH IMPACT THE BURDEN OF METS. YOGA, A FORM OF PHYSICAL ACTIVITY THAT INCORPORATES PSYCHOLOGICAL COMPONENTS (E.G., MAINTAINING ATTENTION, RELAXATION), IS A PROMISING INTERVENTION FOR IMPROVING THE BURDEN OF METS. THIS RANDOMIZED CONTROLLED TRIAL ASSESSED THE FEASIBILITY AND PRELIMINARY EFFICACY OF A 12-WEEK YOGA PROGRAM COUPLED WITH AN EVIDENCE-BASED HEALTH EDUCATION PROGRAM (HED) COMPARED TO HED ALONE. A SECONDARY, EXPLORATORY AIM EXAMINED PERCEIVED STRESS, QUALITY OF LIFE, AND RELATED PSYCHOLOGICAL OUTCOMES (MINDFULNESS, PERCEIVED HEALTH COMPETENCE, AND MOOD). SIXTY-SEVEN ADULTS AT RISK FOR METS ENROLLED (MEAN AGE [SD]: 58 [10] YEARS; 50% MALE; 79% NON-HISPANIC WHITE). PRELIMINARY RESULTS REVEALED SIGNIFICANTLY LARGER IMPROVEMENTS IN TWO QUALITY OF LIFE DOMAINS (ROLE-PHYSICAL AND GENERAL HEALTH PERCEPTIONS) IN THE HED PLUS YOGA GROUP VERSUS HED ALONE (PS < 0.05). THIS IS THE FIRST STUDY THAT IMPLEMENTED LIFESTYLE EDUCATION ALONG WITH YOGA TO EVALUATE THE POTENTIAL UNIQUE EFFECTS OF YOGA ON PARTICIPANTS AT RISK FOR METS. A LARGER CLINICAL TRIAL IS WARRANTED TO FURTHER INVESTIGATE THESE PROMISING PATIENT-REPORTED OUTCOMES.	2016	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
12 2830  37 YOGA VS STRETCHING IN VETERANS WITH CHRONIC LOWER BACK PAIN AND THE ROLE OF MINDFULNESS: A PILOT RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: THE PURPOSE OF THIS STUDY WAS TO INVESTIGATE THE FEASIBILITY OF RECRUITING, RANDOMIZING, ENROLLING, AND COLLECTING OUTCOME DATA ON VETERAN PATIENTS WITH CHRONIC LOW BACK PAIN (CLBP) WHO UNDERGO AN 8-WEEK, ACTIVE EXERCISE CLASS WITH MINDFULNESS (YOGA CLASS) AND WITHOUT (STRETCHING CLASS). METHODS: UNITED STATES VETERANS WITH CLBP BASED ON INCLUSION/EXCLUSION CRITERIA WERE RANDOMIZED TO 1 OF 2 GROUPS. THE STUDY DESIGN WAS A PILOT RANDOMIZED CONTROLLED TRIAL. TWENTY CLBP PATIENTS ATTENDED A YOGA CLASS OR STRETCHING CLASS ONCE PER WEEK FOR 8 WEEKS AT THE VETERANS AFFAIRS ROCHESTER OUTPATIENT CENTER, ROCHESTER, NEW YORK. THE FOLLOWING MEASUREMENTS WERE OBTAINED: RECRUITMENT OR ENROLLMENT DATA, COMPLIANCE DATA TO INCLUDE CLASS ATTENDANCE AND HOME EXERCISE, AND COMPLIANCE DATA REGARDING ABILITY TO COLLECT OUTCOME MEASURES AT BASELINE AND AT COMPLETION. OUTCOME MEASURES INCLUDED PAIN (PEG), QUALITY OF LIFE (PROMIS GLOBAL HEALTH SURVEY), SELF-EFFICACY (2-ITEM QUESTIONNAIRE), FEAR AVOIDANCE BELIEF, CATASTROPHIZING, AND SOCIAL ENGAGEMENT IN ADDITION TO QUALITATIVE CLINICIAN OPEN-ENDED QUESTIONS POSTINTERVENTION. RESULTS: FORTY-FIVE VETERANS WERE QUERIED REGARDING INTEREST IN PARTICIPATION. OF THESE, 34 (76%) MET THE STUDY'S CRITERIA. TWENTY (44%) AGREED TO PARTICIPATE AND WERE CONSENTED, RANDOMIZED, AND ENROLLED IN THE STUDY. INITIAL AND FINAL OUTCOME MEASURES WERE OBTAINED FOR EACH PARTICIPANT (100%). FORTY PERCENT ATTENDED MORE THAN 80% OF THE SESSIONS FOR BOTH YOGA AND STRETCHING GROUPS. CONCLUSION: THIS PILOT STUDY DEMONSTRATED FEASIBILITY OF RECRUITING, ENROLLING, AND COLLECTING OUTCOME DATA ON CLBP VETERAN PATIENTS PARTICIPATING IN YOGA AND STRETCHING CLASS. THE DATA FROM THIS PILOT WILL INFORM THE DEVELOPMENT OF A RANDOMIZED, COMPARATIVE EFFECTIVENESS STUDY OF YOGA WITH AND WITHOUT MINDFULNESS IN THE MANAGEMENT OF CLBP.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
13  445  24 CHAIR YOGA: FEASIBILITY AND SUSTAINABILITY STUDY WITH OLDER COMMUNITY-DWELLING ADULTS WITH OSTEOARTHRITIS. THIS STUDY MEASURED THE FEASIBILITY OF COMPLETING A RANDOMIZED CONTROL TRIAL ON AN 8-WEEK SEATED YOGA PROGRAM FOR OLDER ADULTS WITH OSTEOARTHRITIS. PART OF THE FEASIBILITY OF THIS PROGRAM WAS TO DETERMINE WHETHER PARTICIPANTS WOULD CONTINUE THE YOGA PRACTICE AT HOME USING A GUIDE BOOK AFTER THE 8-WEEK PROGRAM. FINDINGS DEMONSTRATED THAT ONCE PARTICIPANTS WERE NOT IN A GROUP SETTING FOR THE YOGA, THEY DID NOT CONTINUE WITH YOGA PRACTICE. THIS OUTCOME DEMONSTRATES THE NEED FOR GROUP PROGRAMS FOR OLDER ADULTS TO PROMOTE ADHERENCE TO MOVEMENT-BASED PROGRAMS. (TRIAL REGISTRATION: CLINICALTRIALS.GOV: NCT02113410).	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
14 2367  30 WEEKLY ASSESSMENT OF NUMBER OF YOGA CLASSES AND AMOUNT OF YOGA HOME PRACTICE: AGREEMENT WITH DAILY DIARIES. OBJECTIVE: TO EVALUATE A WEEKLY YOGA PRACTICE ASSESSMENT INSTRUMENT DESIGNED TO ASSESS NUMBER OF CLASSES ATTENDED IN THE PREVIOUS WEEK, NUMBER OF TIMES ENGAGED IN FORMAL HOME YOGA PRACTICE, TOTAL NUMBER OF MINUTES ENGAGED IN FORMAL HOME YOGA PRACTICE IN THE PAST WEEK, AND NUMBER OF TIMES ENGAGED IN INFORMAL HOME YOGA PRACTICE. "INFORMAL" PRACTICE WAS DEFINED AS "IN THE MIDDLE OF OTHER ACTIVITIES, YOU SPENT A FEW MOMENTS ENGAGED IN ASANAS/POSTURES, FOCUS ON BREATH, BODY AWARENESS, OR VERY BRIEF MEDITATION, FOR LESS THAN 5 MIN AT A TIME." WE ASSESSED AGREEMENT BETWEEN THIS WEEKLY ASSESSMENT AND A DAILY HOME PRACTICE LOG. DESIGN AND SETTING: SEVENTY-TWO COMMUNITY YOGA PRACTITIONERS COMPLETED ONLINE DAILY YOGA LOGS FOR 28 DAYS AS WELL AS THE WEEKLY YOGA PRACTICE ASSESSMENT FOUR TIMES OVER THE 28 DAY PERIOD. RESULTS: WE EXAMINED AGREEMENT BETWEEN THE TWO METHODS ON THE FOUR INDICES OF AMOUNT OF WEEKLY YOGA PRACTICE. WE FOUND ACCEPTABLE AGREEMENT BETWEEN THE TWO METHODS FOR NUMBER OF CLASSES, NUMBER OF TIMES ENGAGED IN FORMAL HOME PRACTICE, AND TOTAL NUMBER OF MINUTES ENGAGED IN FORMAL HOME PRACTICE. AGREEMENT WAS LOWER FOR NUMBER OF TIMES ENGAGED IN INFORMAL PRACTICE. CONCLUSIONS: THESE DATA PROVIDE SUPPORT FOR USE OF A WEEKLY YOGA PRACTICE ASSESSMENT TO ASSESS NUMBER OF CLASSES ATTENDED AND AMOUNT OF FORMAL BUT NOT INFORMAL HOME PRACTICE.	2019	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
15 1243  47 FEASIBILITY OF A YOGA, AEROBIC AND STRETCHING-TONING EXERCISE PROGRAM FOR ADULT CANCER SURVIVORS: THE STAYFIT TRIAL. BACKGROUND: THE USE OF YOGA AS A MIND-BODY PRACTICE HAS BECOME INCREASINGLY POPULAR AMONG CLINICAL POPULATIONS AND OLDER ADULTS WHO USE THIS PRACTICE TO MANAGE AGE AND CHRONIC DISEASE-RELATED SYMPTOMS. ALTHOUGH YOGA CONTINUES TO GAIN POPULARITY AMONG PRACTITIONERS AND RESEARCHERS, PILOT STUDIES THAT EXAMINE ITS FEASIBILITY AND ACCEPTABILITY, ESPECIALLY AMONG CANCER SURVIVORS, ARE LIMITED. FEASIBILITY STUDIES PLAY A CRITICAL ROLE IN DETERMINING WHETHER THE TARGET POPULATION IS LIKELY TO ENGAGE WITH LARGER SCALE EFFICACY AND EFFECTIVENESS TRIALS. IN THIS PAPER WE PRESENT FEASIBILITY AND ACCEPTABILITY DATA FROM A 12-WEEK RANDOMIZED CONTROLLED TRIAL (RCT) CONDUCTED WITH ADULT CANCER SURVIVORS. METHODS: PARTICIPANTS N = 78 (MEAN AGE: 55 YEARS) WERE RANDOMIZED TO ONE OF THREE GROUPS: A HATHA YOGA, AEROBIC EXERCISE, OR STRETCHING-TONING CONTROL GROUP WITH GROUP EXERCISE CLASSES HELD FOR 150 MIN/WEEK FOR 12 WEEKS. HEREIN WE REPORT FEASIBILITY AND ACCEPTABILITY, INCLUDING ENROLLMENT RATES, ATTENDANCE, ATTRITION AND ADVERSE EVENTS, AND PARTICIPANT FEEDBACK AND SATISFACTION DATA. RESULTS: OF THE 233 ADULTS SCREENED, 109 WERE ELIGIBLE AND 78 RANDOMIZED TO ONE OF THE THREE INTERVENTION ARMS. SESSION ATTENDANCE WAS HIGH FOR ALL GROUPS (75.5-89.5%) AND 17 PARTICIPANTS DROPPED OUT DURING THE 12-WEEK INTERVENTION. PROGRAM SATISFACTION WAS HIGH (4.8 OR HIGHER OUT OF 5) AND NO ADVERSE EVENTS WERE REPORTED. ONE COHORT (N = 15) OF THE INTERVENTION TRANSITIONED TO REMOTE INTERVENTION DELIVERY DUE TO THE COVID-19 PANDEMIC. FEASIBILITY DATA FROM THESE PARTICIPANTS SUGGESTED THAT SYNCHRONIZED GROUP EXERCISE CLASSES VIA ZOOM WITH A LIVE INSTRUCTOR WERE ACCEPTABLE AND ENJOYABLE. PARTICIPANT FEEDBACK REGARDING MOST AND LEAST HELPFUL ASPECTS OF THE PROGRAM AS WELL AS SUGGESTIONS FOR FUTURE YOGA INTERVENTIONS ARE SUMMARIZED. CONCLUSIONS: OVERALL, THE YOGA INTERVENTION WAS HIGHLY FEASIBLE AND ACCEPTABLE. THE FEASIBILITY PARAMETERS FROM THIS TRIAL CAN AID RESEARCHERS IN ESTIMATING RECRUITMENT RATES FOR DESIRED SAMPLE SIZES TO SUCCESSFULLY RANDOMIZE AND RETAIN CANCER SURVIVORS IN SHORT- AND LONG-TERM YOGA-BASED EFFICACY AND EFFECTIVENESS TRIALS. THE FINDINGS ALSO PROVIDE EVIDENCE TO CLINICIANS WHO CAN RECOMMEND UP TO 150 MIN OF A COMBINATION OF EXERCISES-AEROBIC, YOGA, OR STRETCHING-TONING TO THEIR CANCER PATIENTS IN ORDER TO IMPROVE HEALTH AND WELLBEING DURING CANCER SURVIVORSHIP.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
16 1414  38 IMPLEMENTING YOGA THERAPY ADAPTED FOR OLDER VETERANS WHO ARE CANCER SURVIVORS. OBJECTIVES: THIS GOAL OF THIS PAPER IS TO DESCRIBE THE REACH, APPLICATION, AND EFFECTIVENESS OF AN 8-WEEK YOGA THERAPY PROTOCOL WITH OLDER CANCER SURVIVORS WITHIN A VETERANS HEALTH ADMINISTRATION SETTING. METHODS: TO DOCUMENT THE REACH OF THIS INTERVENTION, RECRUITMENT EFFORTS, ATTENDANCE, AND PRACTICE RATES WERE TRACKED. TO EXPLORE THE APPLICATION OF THE PROTOCOL TO THIS POPULATION, PHYSICAL THERAPY PRE-ASSESSMENT AND OBSERVATIONS BY THE YOGA THERAPIST WERE RECORDED TO ASCERTAIN NECESSARY POSE MODIFICATIONS. EFFECTIVENESS WAS MEASURED THROUGH PRE- AND POST-COURSE STRUCTURED INTERVIEWS, TRACKING SELF-REPORTED SYMPTOMS OF COMBAT-RELATED POSTTRAUMATIC STRESS DISORDER, DEPRESSION, ANXIETY, FATIGUE, INSOMNIA, AND PAIN. RESULTS: REGARDING REACH, 15% OF ELIGIBLE VETERANS (N = 14) ENROLLED, PARTICIPATED IN 3-16 CLASSES (M+/-SD = 11.64+/-3.39), AND PRACTICED AT HOME FOR 0-56 DAYS (M+/-SD = 26.36+/-17.87). PARTICIPANTS WERE PRIMARILY CAUCASIAN (N = 13), MALE (N = 13), RANGED IN AGE FROM 55 TO 78 YEARS (M+/-SD = 65.64+/-5.15), AND HAD MULTIPLE MEDICAL PROBLEMS. DURING APPLICATION, SUBSTANTIAL INDIVIDUALIZED MODIFICATIONS TO THE YOGA THERAPY PROTOCOL WERE NECESSARY. EFFECTIVENESS OF THE INTERVENTION WAS MIXED. DURING POST-COURSE INTERVIEWS, PARTICIPANTS REPORTED A VARIETY OF QUALITATIVE BENEFITS. NOTABLY, THE MAJORITY OF PARTICIPANTS REPORTED THAT BREATHING AND RELAXATION TECHNIQUES WERE THE MOST USEFUL TO LEARN. GROUP COMPARISONS OF MEAN PRE- AND POST-COURSE SCORES ON STANDARDIZED MEASURES SHOWED NO SIGNIFICANT DIFFERENCES. CONCLUSIONS: A MINORITY OF OLDER VETERANS EXPRESS AN INTEREST IN YOGA, BUT THOSE WHO DO HAVE HIGH RATES OF CLASS ATTENDANCE AND HOME PRACTICE. CAREFUL PHYSICAL PRE-ASSESSMENT AND ATTENTIVE THERAPISTS ARE REQUIRED TO UNDERTAKE THE ADAPTATIONS REQUIRED BY PARTICIPANTS WITH MULTIPLE COMORBIDITIES. THE EFFECTIVENESS OF YOGA IN THIS SETTING REQUIRES ADDITIONAL STUDY.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
17 1241  45 FEASIBILITY OF A YOGA INTERVENTION FOR INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: YOGA IS A POTENTIALLY LOW RISK INTERVENTION FOR COGNITIVE IMPAIRMENT THAT COMBINES MENTAL AND PHYSICAL PRACTICE AND INCLUDES INSTRUCTION ON BREATHING, STRESS REDUCTION, AND MINDFULNESS MEDITATION. PREVIOUS RESEARCH DOCUMENTS THAT YOGA CAN TARGET MODIFIABLE RISK FACTORS FOR MILD COGNITIVE IMPAIRMENT (MCI) PROGRESSION. THE AUTHORS DESCRIBE A RANDOMIZED FEASIBILITY TRIAL OF YOGA FOR INDIVIDUALS WITH MCI. METHODS: PARTICIPANTS WERE 37 INDIVIDUALS WITH AMNESTIC MCI WHO WERE RANDOMLY ASSIGNED TO RECEIVE 12 WEEKS OF TWICE-WEEKLY YOGA INTERVENTION (YI) OR HEALTHY LIVING EDUCATION (HLE) CLASSES. ACCEPTABILITY AND FEASIBILITY WERE ASSESSED BY TRACKING ADVERSE EVENTS, CLASS ATTENDANCE, AND PARTICIPANT SATISFACTION. PARTICIPANTS COMPLETED NEUROPSYCHOLOGICAL AND MOOD MEASURES AS WELL AS MEASURES OF POTENTIAL INTERVENTION MECHANISMS AT BASELINE AND IMMEDIATELY POSTINTERVENTION. RESULTS: PARTICIPANTS IN BOTH CONDITIONS REPORTED HIGH LEVELS OF SATISFACTION AND REASONABLE CLASS ATTENDANCE RATES. HOME PRACTICE RATES WERE LOW. THERE WERE NO ADVERSE EVENTS DEEMED RELATED TO THE YI. RESULTS SHOWED A MEDIUM EFFECT SIZE IN FAVOR OF THE YI IN VISUOSPATIAL SKILLS. THE YOGA GROUP ALSO SHOWED A LARGE EFFECT SIZE INDICATING DECLINE IN PERCEIVED STRESS COMPARED WITH THE HLE GROUP, WHEREAS HLE RESULTED IN GREATER REDUCTIONS IN DEPRESSIVE SYMPTOMS AFTER THE INTERVENTION (LARGE EFFECT SIZE). CONCLUSIONS: STUDY FINDINGS INDICATED THAT THE YI WAS SAFE, MODESTLY FEASIBLE, AND ACCEPTABLE TO OLDER ADULTS WITH MCI. THE AUTHORS FOUND PRELIMINARY EVIDENCE THAT YOGA MAY IMPROVE VISUOSPATIAL FUNCTIONING IN INDIVIDUALS WITH MCI. RESULTS SUPPORT STRESS REDUCTION AS A POSSIBLE MECHANISM FOR THE YI. FUTURE STUDIES SHOULD ADDRESS A YI IN A LARGER SAMPLE AND INCLUDE STRATEGIES TO ENHANCE ENGAGEMENT AND HOME PRACTICE.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
18  608  47 DEVELOPMENT OF A FALLS REDUCTION YOGA PROGRAM FOR OLDER ADULTS-A PILOT STUDY. OBJECTIVES: WORK WITH LOCAL RURAL ORGANIZATIONS TO DEVELOP AN EVIDENCE-BASED HATHA YOGA PROGRAM INTENDED TO IMPROVE CORE STRENGTH AND BALANCE TO REDUCE FALLS RISK. FEASIBILITY DETERMINED BY SUCCESSFUL RECRUITING, INTERVENTION AND EVALUATION OF PARTICIPANTS AND ACCEPTABLE FREQUENCY OF ADVERSE EVENTS. DESIGN: SINGLE-ARM PILOT STUDY. SETTING: RURAL WISCONSIN TOWN OF 4200 PEOPLE. INTERVENTION: EIGHT WEEK YOGA PROGRAM WITH WEEKLY GROUP CLASSES AND HOME YOGA PRACTICE THREE TIMES PER WEEK. MAIN OUTCOME MEASURES: THE PRIMARY OUTCOMES WERE (1) ABILITY TO ENROLL AT LEAST 20 PARTICIPANTS, (2) PARTICIPANT COMPLETION OF INTERVENTION AND POST-INTERVENTION EVALUATION, AND (3) ADVERSE EVENT DESCRIPTION AND FREQUENCY. RESULTS: A CONVENIENCE SAMPLE OF 20 ADULTS OVER AGE 59 WAS ENROLLED AND STARTED THE PROGRAM WITH ONE DROP OUT. PARTICIPANTS ATTENDED A MEAN OF 7.1 (SD 1.47) OF THE 8 CLASSES AND A TOTAL OF 141 OUT OF 160 (88.1%) CLASSES. NINETEEN (95%) COMPLETED FOLLOW UP EVALUATION. PARTICIPANTS REPORTED 4 FALLS IN THE MONTH BEFORE THE INTERVENTION AND 1 FALL THE MONTH BEFORE THE POST-INTERVENTION EVALUATION (P=0.34). NO OTHER SERIOUS ADVERSE EVENTS OCCURRED. CONCLUSIONS: THIS PROJECT SUGGESTS AN EVIDENCE-BASED YOGA PROGRAM DESIGNED TO IMPROVE CORE STRENGTH AND BALANCE IS FEASIBLE AND ACCEPTABLE TO PARTICIPANTS. FUTURE RESEARCH WILL INCLUDE A RANDOMIZED TRIAL TO ASSESS IMPACT ON FALLS RISK.	2017	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
19  345  46 ASSESSING FEASIBILITY AND ACCEPTABILITY OF YOGA AND GROUP CBT FOR ADOLESCENTS WITH DEPRESSION: A PILOT RANDOMIZED CLINICAL TRIAL. PURPOSE: GIVEN INCREASING RATES OF DEPRESSION IN ADOLESCENTS, THERE IS A CLEAR NEED FOR INNOVATIVE TREATMENTS. IN THIS PILOT RANDOMIZED CLINICAL TRIAL, WE ASSESSED ACCEPTABILITY AND FEASIBILITY OF TWO GROUP-BASED INTERVENTIONS: YOGA AND COGNITIVE-BEHAVIORAL THERAPY (CBT). THE GOAL OF THIS WORK IS TO PREPARE FOR A FUTURE FULLY POWERED RANDOMIZED TRIAL TO TEST THE HYPOTHESIS THAT YOGA IS NOT INFERIOR TO AN ESTABLISHED ADOLESCENT DEPRESSION TREATMENT, NAMELY, GROUP CBT. METHODS: WE ENROLLED 42 ADOLESCENTS WITH ELEVATED DEPRESSION SYMPTOMS. PARTICIPANTS WERE RANDOMLY ASSIGNED TO A 12-WEEK GROUP-BASED INTERVENTION, YOGA OR CBT. WE HAD A PRIORI FEASIBILITY AND ACCEPTABILITY TARGETS, INCLUDING FOR RECRUITMENT RATE, RETENTION RATE, EXPECTANCY, CREDIBILITY, PROGRAM SATISFACTION, CLASS ATTENDANCE, ENGAGEMENT IN HOME PRACTICE, AND INSTRUCTOR/LEADER MANUAL ADHERENCE. WE ASSESSED ADVERSE EVENTS, AND WITHIN-SUBJECT CHANGES IN OUTCOMES (DEPRESSION, ANXIETY, IMPAIRMENT, SLEEP DISTURBANCE) AND POSSIBLE MEDIATORS (MINDFULNESS, SELF-COMPASSION). RESULTS: BOTH INTERVENTIONS MET MOST ACCEPTABILITY AND FEASIBILITY TARGETS. THE ONLY TARGET NOT MET RELATED TO LOW ENGAGEMENT IN HOME PRACTICE. PARTICIPANTS WITHIN EACH STUDY ARM SHOWED DECREASED DEPRESSION SYMPTOMS OVER TIME AND INCREASED SELF-COMPASSION. CONCLUSIONS: A YOGA INTERVENTION APPEARS TO BE ACCEPTABLE AND FEASIBLE TO ADOLESCENTS WITH DEPRESSION. HOWEVER, IT MAY BE CHALLENGING FOR THIS GROUP TO ENGAGE IN UNSTRUCTURED HOME PRACTICE.	2022	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
20  119  37 A PILOT STUDY OF THE ACCEPTABILITY, FEASIBILITY AND SAFETY OF YOGA FOR CHRONIC PAIN IN SICKLE CELL DISEASE. OBJECTIVES: TO DETERMINE THE ACCEPTABILITY, FEASIBILITY AND SAFETY OF YOGA FOR CHRONIC PAIN IN SICKLE CELL DISEASE. DESIGN AND SETTING: IN PART A OF THIS TWO-PART STUDY, ADOLESCENTS WITH SCD AND CHRONIC PAIN (GROUP 1) AND THEIR PARENT (GROUP 2) COMPLETED A SURVEY DESIGNED TO CAPTURE PAIN CHARACTERISTICS, ATTITUDES AND PRACTICES RELATED TO YOGA, AND POTENTIAL ACCEPTABILITY OF A YOGA PROGRAM. IN PART B, THE STUDY ASSESSED THE FEASIBILITY AND SAFETY OF AN INSTRUCTOR-LED GROUP YOGA PROGRAM. THE STUDY WAS REGISTERED ON CLINICALTRIALS.GOV (NCT03694548). INTERVENTION: EIGHT INSTRUCTOR-LED GROUP YOGA SESSIONS. MAIN OUTCOME MEASURES: FEASIBILITY AND SAFETY OUTCOMES WERE CHOSEN A PRIORI, AS FOLLOWS: 1) PROPORTION OF ADOLESCENT PATIENTS WITH SCD AND CHRONIC PAIN APPROACHED THAT CONSENT TO PARTICIPATE IN PART A, 2) PROPORTION OF ADOLESCENT PARTICIPANTS ENROLLED IN PART A THAT CONSENT TO PARTICIPATE IN PART B, 3) PROPORTION OF PARTICIPANTS ENROLLED IN PART B THAT ATTEND AT LEAST 6 OF 8 YOGA SESSIONS, 4) PROPORTION OF PARTICIPANTS ENROLLED IN PART B WITH AN ED VISIT OR A HOSPITALIZATION FOR PAIN WITHIN 24 H OF COMPLETION OF EACH YOGA SESSION, 5) PROPORTION OF PARTICIPANTS IN PART B WHO COMPLETE ALL STUDY ASSESSMENTS BEFORE, AND AT THE END OF THE YOGA PROGRAM, 6) ADHERENCE TO SUBMISSION OF PAIN DIARY. RESULTS: THE MEDIAN AGE OF 15 PATIENT PARTICIPANTS IN PART A WAS 16 (IQR 14-17), AND 14 PARENTS WAS 43.5 (IQR 42-51). MOST PARTICIPANTS WERE FEMALE. MOST PARTICIPANT RESPONSES INDICATED A POSITIVE OPINION OF YOGA. NINE ADOLESCENTS (60 %) FROM PART A PARTICIPATED IN PART B OF THE STUDY. THE MEDIAN AGE OF 9 PARTICIPANTS IN PART B WAS 17 (IQR 15-18), AND 5 OF THE 9 PARTICIPANTS WERE FEMALE (53.3 %). ONLY ONE PARTICIPANT WAS ABLE TO ATTEND 3 OF THE 8 YOGA SESSIONS OFFERED, AND DID NOT EXPERIENCE ANY ED VISITS OR HOSPITALIZATIONS FOLLOWING THE YOGA SESSIONS. NONE OF THE OTHER FEASIBILITY ENDPOINTS WERE MET IN THIS STUDY. CONCLUSIONS: PATIENTS WITH SCD AND CHRONIC PAIN OVERALL HAVE A POSITIVE OPINION OF YOGA, BUT THERE ARE CHALLENGES WITH RECRUITMENT AND RETENTION OF PARTICIPANTS IN A CLINICAL TRIAL OF YOGA, AND BARRIERS TO FEASIBILITY OF AN IN-PERSON GROUP YOGA INTERVENTION.	2021